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Search of human proteins with 40807447
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40807447 papillary renal cell carcinoma
translocation-associated gene product isoform 1 [Homo sapiens]
(491 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40807447 papillary renal cell carcinoma translocation-associa... 1006 0.0
gi|40807450 papillary renal cell carcinoma translocation-associa... 922 0.0
gi|160707881 formin 2 [Homo sapiens] 71 3e-12
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 70 6e-12
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 70 6e-12
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 70 6e-12
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 69 1e-11
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 69 1e-11
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 68 2e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni... 67 5e-11
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 66 8e-11
gi|11386183 WAS protein family, member 2 [Homo sapiens] 65 1e-10
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 65 2e-10
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 65 2e-10
gi|56549694 enabled homolog isoform a [Homo sapiens] 64 4e-10
gi|39930375 enabled homolog isoform b [Homo sapiens] 64 4e-10
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 62 1e-09
gi|150417989 cyclin K isoform 1 [Homo sapiens] 62 2e-09
gi|55749531 splicing factor 3B subunit 2 [Homo sapiens] 62 2e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 61 3e-09
gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] 60 5e-09
gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] 60 5e-09
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 60 5e-09
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 60 5e-09
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 60 5e-09
gi|7706501 WW domain binding protein 11 [Homo sapiens] 60 5e-09
gi|157168329 formin 1 [Homo sapiens] 60 6e-09
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 59 8e-09
gi|210032580 SET domain containing 1B [Homo sapiens] 59 1e-08
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 58 2e-08
>gi|40807447 papillary renal cell carcinoma translocation-associated
gene product isoform 1 [Homo sapiens]
Length = 491
Score = 1006 bits (2600), Expect = 0.0
Identities = 491/491 (100%), Positives = 491/491 (100%)
Query: 1 MSLVAYASSDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAP 60
MSLVAYASSDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAP
Sbjct: 1 MSLVAYASSDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAP 60
Query: 61 AFPPPLLLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGL 120
AFPPPLLLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGL
Sbjct: 61 AFPPPLLLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGL 120
Query: 121 NLPPPIGGAGPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGL 180
NLPPPIGGAGPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGL
Sbjct: 121 NLPPPIGGAGPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGL 180
Query: 181 SALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTP 240
SALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTP
Sbjct: 181 SALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTP 240
Query: 241 SPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPE 300
SPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPE
Sbjct: 241 SPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPE 300
Query: 301 ELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFSTYGDANAAGAYY 360
ELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFSTYGDANAAGAYY
Sbjct: 301 ELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFSTYGDANAAGAYY 360
Query: 361 QDYYSGGYYPAQDPALVPPQEIAPDASFIDDEAFKRLQGKRNRGREEINFVEIKGDDQLS 420
QDYYSGGYYPAQDPALVPPQEIAPDASFIDDEAFKRLQGKRNRGREEINFVEIKGDDQLS
Sbjct: 361 QDYYSGGYYPAQDPALVPPQEIAPDASFIDDEAFKRLQGKRNRGREEINFVEIKGDDQLS 420
Query: 421 GAQQWMTKSLTEEKTMKSFSKKKGEQPTGQQRRKHQITYLIHQAKERELELKNTWSENKL 480
GAQQWMTKSLTEEKTMKSFSKKKGEQPTGQQRRKHQITYLIHQAKERELELKNTWSENKL
Sbjct: 421 GAQQWMTKSLTEEKTMKSFSKKKGEQPTGQQRRKHQITYLIHQAKERELELKNTWSENKL 480
Query: 481 SRRQTQAKYGF 491
SRRQTQAKYGF
Sbjct: 481 SRRQTQAKYGF 491
>gi|40807450 papillary renal cell carcinoma translocation-associated
gene product isoform 2 [Homo sapiens]
Length = 459
Score = 922 bits (2382), Expect = 0.0
Identities = 459/491 (93%), Positives = 459/491 (93%), Gaps = 32/491 (6%)
Query: 1 MSLVAYASSDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAP 60
MSLVAYASSDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAP
Sbjct: 1 MSLVAYASSDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAP 60
Query: 61 AFPPPLLLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGL 120
AFPPPLLLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGL
Sbjct: 61 AFPPPLLLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGL 120
Query: 121 NLPPPIGGAGPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGL 180
NLPPPIGGAGPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGL
Sbjct: 121 NLPPPIGGAGPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGL 180
Query: 181 SALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTP 240
SALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTP
Sbjct: 181 SALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTP 240
Query: 241 SPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPE 300
SPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPE
Sbjct: 241 SPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPE 300
Query: 301 ELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFSTYGDANAAGAYY 360
ELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFSTYGDANAAGAYY
Sbjct: 301 ELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFSTYGDANAAGAYY 360
Query: 361 QDYYSGGYYPAQDPALVPPQEIAPDASFIDDEAFKRLQGKRNRGREEINFVEIKGDDQLS 420
Q FKRLQGKRNRGREEINFVEIKGDDQLS
Sbjct: 361 Q--------------------------------FKRLQGKRNRGREEINFVEIKGDDQLS 388
Query: 421 GAQQWMTKSLTEEKTMKSFSKKKGEQPTGQQRRKHQITYLIHQAKERELELKNTWSENKL 480
GAQQWMTKSLTEEKTMKSFSKKKGEQPTGQQRRKHQITYLIHQAKERELELKNTWSENKL
Sbjct: 389 GAQQWMTKSLTEEKTMKSFSKKKGEQPTGQQRRKHQITYLIHQAKERELELKNTWSENKL 448
Query: 481 SRRQTQAKYGF 491
SRRQTQAKYGF
Sbjct: 449 SRRQTQAKYGF 459
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 70.9 bits (172), Expect = 3e-12
Identities = 52/142 (36%), Positives = 60/142 (42%), Gaps = 19/142 (13%)
Query: 14 PDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLL----- 68
P P P A P L G LP P A +PPPP + PPP L
Sbjct: 938 PGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 997
Query: 69 --PPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSP---RGPGLNLP 123
PPP + PPPPLP G PPPP + A G G+P P G G+ P
Sbjct: 998 PPPPPLPGAGIPPPPPLPG--AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1055
Query: 124 PPIGGAG----PPL---GLPKP 138
PP+ GAG PPL G+P P
Sbjct: 1056 PPLPGAGIPPPPPLPGAGIPPP 1077
Score = 69.3 bits (168), Expect = 7e-12
Identities = 52/136 (38%), Positives = 59/136 (43%), Gaps = 18/136 (13%)
Query: 19 PEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLL------LPPPT 72
P P A P P G LP G + PPPP A PPP L LPPP
Sbjct: 911 PPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPL 970
Query: 73 GDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSP---RGPGLNLPPPIGGA 129
+ PPPPLP G PPPP + A G G+P P G G+ PPP+ GA
Sbjct: 971 PGAGIPPPPPLPG--AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1028
Query: 130 G----PPL---GLPKP 138
G PPL G+P P
Sbjct: 1029 GIPPPPPLPGAGIPPP 1044
Score = 68.9 bits (167), Expect = 1e-11
Identities = 47/133 (35%), Positives = 56/133 (42%), Gaps = 8/133 (6%)
Query: 14 PDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLP---- 69
P P P P L G+ P P A +PPPP + PPP LP
Sbjct: 1081 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1140
Query: 70 -PPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSP---RGPGLNLPPP 125
PP PR+ PPP P G PPPP + A G+G+P P G G+ PPP
Sbjct: 1141 PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP 1200
Query: 126 IGGAGPPLGLPKP 138
+ GAG P P P
Sbjct: 1201 LPGAGIPPPPPLP 1213
Score = 67.0 bits (162), Expect = 4e-11
Identities = 54/156 (34%), Positives = 64/156 (41%), Gaps = 36/156 (23%)
Query: 14 PDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLP---- 69
P P P P L G P P A +PPPP + PPP LP
Sbjct: 993 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1052
Query: 70 ---PPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGV-------GEGL-------GLGL 112
PP + PPPPLP G PPPP P AG+ G G+ G+G+
Sbjct: 1053 PPPPPLPGAGIPPPPPLPGA--GIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGVGI 1107
Query: 113 PSP---RGPGLNLPPPIGGAG----PPL---GLPKP 138
P P G G+ PPP+ GAG PPL G+P P
Sbjct: 1108 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1143
Score = 65.9 bits (159), Expect = 8e-11
Identities = 54/156 (34%), Positives = 63/156 (40%), Gaps = 36/156 (23%)
Query: 14 PDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLP---- 69
P P P P L G P P A +PPPP + PPP LP
Sbjct: 1004 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1063
Query: 70 ---PPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGV-------GEGL-------GLGL 112
PP + PPPPLP G PPPP P AG+ G G+ G G+
Sbjct: 1064 PPPPPLPGAGIPPPPPLPGA--GIPPPP---PLPGAGIPPPPPLPGVGIPPPPPLPGAGI 1118
Query: 113 PSPR---GPGLNLPPPIGGAG----PPL---GLPKP 138
P P G G+ PPP+ GAG PPL G+P P
Sbjct: 1119 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPP 1154
Score = 60.8 bits (146), Expect = 3e-09
Identities = 37/100 (37%), Positives = 46/100 (46%), Gaps = 8/100 (8%)
Query: 47 GPALLPPPPQ----MLAPAFPPPLL-LPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEA 101
G ++PPPP M P P + PPP + PPPP P G PPPP + A
Sbjct: 872 GLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGI 931
Query: 102 AGVGEGLGLGLPSP---RGPGLNLPPPIGGAGPPLGLPKP 138
+ G G+P P G + PPP+ GAG PL P P
Sbjct: 932 LPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLP 971
Score = 54.7 bits (130), Expect = 2e-07
Identities = 45/139 (32%), Positives = 59/139 (42%), Gaps = 6/139 (4%)
Query: 14 PDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPPPTG 73
P P P P L G+ P P +PPPP + PPP LP
Sbjct: 1158 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGI 1217
Query: 74 DPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLG-LPSPRGPGLNLPPPIGGAGPP 132
P P PPLP G PPPP + P + +G LP+P+ G LPPP+
Sbjct: 1218 PP--APAPPLPPPGTGIPPPP-LLPVSGPPLLPQVGSSTLPTPQVCGF-LPPPLPSGLFG 1273
Query: 133 LGLPKPK-KRKEPVKIAAP 150
LG+ + K RK+P++ P
Sbjct: 1274 LGMNQDKGSRKQPIEPCRP 1292
Score = 53.5 bits (127), Expect = 4e-07
Identities = 48/136 (35%), Positives = 59/136 (43%), Gaps = 34/136 (25%)
Query: 27 VAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPPPTGDPRLQPPPPLPF- 85
+ P P L G+ ++P A+ PPP PPP PPP + PPPPL
Sbjct: 875 MVPPPPPPLPGM--TVPTLPSTAIPQPPPLQGTEMLPPP---PPPLPGAGIPPPPPL--P 927
Query: 86 GLG----------GFPPPPGVSPAEAAGVG-----EGLGLGLPSP-RGPGLNLPPPIGGA 129
G G G PPPP P A + G G+ LP P G G+ PPP+ GA
Sbjct: 928 GAGILPLPPLPGAGIPPPP---PLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGA 984
Query: 130 G----PPL---GLPKP 138
G PPL G+P P
Sbjct: 985 GIPPPPPLPGAGIPPP 1000
Score = 36.2 bits (82), Expect = 0.070
Identities = 39/143 (27%), Positives = 44/143 (30%), Gaps = 57/143 (39%)
Query: 53 PPPQMLAPAFPPPLLLPPPTGDPRLQP----------------------------PPPLP 84
P + P PP LL G P QP PPPLP
Sbjct: 803 PTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLP 862
Query: 85 F--------GLGGFPPPPGVSPAEAAGVGEGLGLGLPSP--------------RGPGLNL 122
GLG PPPP P + P P G G+
Sbjct: 863 CTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPP 922
Query: 123 PPPIGGAG----PPL---GLPKP 138
PPP+ GAG PPL G+P P
Sbjct: 923 PPPLPGAGILPLPPLPGAGIPPP 945
Score = 34.3 bits (77), Expect = 0.26
Identities = 46/172 (26%), Positives = 67/172 (38%), Gaps = 25/172 (14%)
Query: 171 LQGSSEGTGL-SALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSL 229
LQG+ E +A+ PQP +R LL + + GSPDT+ + A SL
Sbjct: 226 LQGAEEPAAPPTAVSPQPGAFL--GLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESL 283
Query: 230 APVVGTTTTTPSPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVE 289
A PSP + +++ +L + ++ S F PE PG E
Sbjct: 284 AAEPREPQQPPSPGGL-PVSEAPSLPAAQPAAKDSPSS-------TAFPFPEAG--PGEE 333
Query: 290 PYPYPIPTVPEELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDD 341
P+ + G E AF+D AP GS G W P+ G+D
Sbjct: 334 AAGAPVRGAGDTDEEG--EEDAFED----AP------RGSPGEEWAPEVGED 373
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 69.7 bits (169), Expect = 6e-12
Identities = 96/359 (26%), Positives = 127/359 (35%), Gaps = 74/359 (20%)
Query: 10 DESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLP 69
D SEP P P + AP P L L P P++ PPPP +L PP L
Sbjct: 153 DISEPPGGSPLPSPP-STAPPPPPLL------LEPPPPPSMAPPPPPVLEALSPPHTLSS 205
Query: 70 P--PTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIG 127
P PT + P PPL F PPPP +PA A SP G L PP G
Sbjct: 206 PSIPTPPDFIPPAPPLAFLAP--PPPPVPAPAPPAPA---------SPHTVGTRLFPPGG 254
Query: 128 GAGPPLGLPKPKKRKEPVKIA---APELHKGDSDSEEDEP---------TKKKTILQGSS 175
+ ++ E + + +P KG + EP T ++ SS
Sbjct: 255 VTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSS 314
Query: 176 EGTGLSALLP-QPKNLTVKETNRLLLPHAFSRKP-SDGSPDTKPSRLASKTKTSSLAPVV 233
+ P + + T K +RL LP +F +P S PD P
Sbjct: 315 IPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPE--------------- 359
Query: 234 GTTTTTPSPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPY 293
P +KA A + + ++ Q + +DE PP P P
Sbjct: 360 -----PDCPGELKATAPA-----SPRLGQSQSQADERA-----------GTPPPAPPLPP 398
Query: 294 PIPTVP---EELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFST 349
P P +P LPP P P Q AA+ P F SS PKP N S+
Sbjct: 399 PAPPLPPPAPPLPPAAPPLPCAQ-KAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASS 456
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 69.7 bits (169), Expect = 6e-12
Identities = 96/359 (26%), Positives = 127/359 (35%), Gaps = 74/359 (20%)
Query: 10 DESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLP 69
D SEP P P + AP P L L P P++ PPPP +L PP L
Sbjct: 153 DISEPPGGSPLPSPP-STAPPPPPLL------LEPPPPPSMAPPPPPVLEALSPPHTLSS 205
Query: 70 P--PTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIG 127
P PT + P PPL F PPPP +PA A SP G L PP G
Sbjct: 206 PSIPTPPDFIPPAPPLAFLAP--PPPPVPAPAPPAPA---------SPHTVGTRLFPPGG 254
Query: 128 GAGPPLGLPKPKKRKEPVKIA---APELHKGDSDSEEDEP---------TKKKTILQGSS 175
+ ++ E + + +P KG + EP T ++ SS
Sbjct: 255 VTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSS 314
Query: 176 EGTGLSALLP-QPKNLTVKETNRLLLPHAFSRKP-SDGSPDTKPSRLASKTKTSSLAPVV 233
+ P + + T K +RL LP +F +P S PD P
Sbjct: 315 IPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPE--------------- 359
Query: 234 GTTTTTPSPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPY 293
P +KA A + + ++ Q + +DE PP P P
Sbjct: 360 -----PDCPGELKATAPA-----SPRLGQSQSQADERA-----------GTPPPAPPLPP 398
Query: 294 PIPTVP---EELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFST 349
P P +P LPP P P Q AA+ P F SS PKP N S+
Sbjct: 399 PAPPLPPPAPPLPPAAPPLPCAQ-KAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASS 456
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 69.7 bits (169), Expect = 6e-12
Identities = 96/359 (26%), Positives = 127/359 (35%), Gaps = 74/359 (20%)
Query: 10 DESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLP 69
D SEP P P + AP P L L P P++ PPPP +L PP L
Sbjct: 153 DISEPPGGSPLPSPP-STAPPPPPLL------LEPPPPPSMAPPPPPVLEALSPPHTLSS 205
Query: 70 P--PTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIG 127
P PT + P PPL F PPPP +PA A SP G L PP G
Sbjct: 206 PSIPTPPDFIPPAPPLAFLAP--PPPPVPAPAPPAPA---------SPHTVGTRLFPPGG 254
Query: 128 GAGPPLGLPKPKKRKEPVKIA---APELHKGDSDSEEDEP---------TKKKTILQGSS 175
+ ++ E + + +P KG + EP T ++ SS
Sbjct: 255 VTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSS 314
Query: 176 EGTGLSALLP-QPKNLTVKETNRLLLPHAFSRKP-SDGSPDTKPSRLASKTKTSSLAPVV 233
+ P + + T K +RL LP +F +P S PD P
Sbjct: 315 IPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPE--------------- 359
Query: 234 GTTTTTPSPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPY 293
P +KA A + + ++ Q + +DE PP P P
Sbjct: 360 -----PDCPGELKATAPA-----SPRLGQSQSQADERA-----------GTPPPAPPLPP 398
Query: 294 PIPTVP---EELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFST 349
P P +P LPP P P Q AA+ P F SS PKP N S+
Sbjct: 399 PAPPLPPPAPPLPPAAPPLPCAQ-KAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASS 456
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 68.6 bits (166), Expect = 1e-11
Identities = 49/140 (35%), Positives = 60/140 (42%), Gaps = 11/140 (7%)
Query: 19 PEPEEEEAVAPTSGPALGGLFASLPA--PKGPALLPPPPQMLAPAFPPPLLLPPPTGDPR 76
P P +A P P G+ P+ P G A+ PPPP + PPP PP G
Sbjct: 633 PPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP--PPLPGSAG 690
Query: 77 LQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGG--AGPPLG 134
+ PPPP G G PPPP P G G+ P P GPG+ PPP G PP G
Sbjct: 691 IPPPPPPLPGEAGMPPPPPPLPG-----GPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFG 745
Query: 135 LPKPKKRKEPVKIAAPELHK 154
P P + +L+K
Sbjct: 746 FGVPAAPVLPFGLTPKKLYK 765
Score = 62.4 bits (150), Expect = 9e-10
Identities = 53/151 (35%), Positives = 63/151 (41%), Gaps = 32/151 (21%)
Query: 19 PEPEEEEAVAPTSGPALGGLFASLPAPK--GPALLPPPPQMLA-----PAFPPPLL---- 67
P P E V S +L G A P P G A +PPPP L P PPPL
Sbjct: 644 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG 703
Query: 68 LPPPT----GDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLP 123
+PPP G P + PPPP P G G PPPP G+G+ P P G G+
Sbjct: 704 MPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP------------GMGMPPPPPFGFGVPAA 751
Query: 124 PPIGGAGPPLGLPKPKKRKEPVKIAAPELHK 154
P + P GL K K V++ P K
Sbjct: 752 PVL-----PFGLTPKKLYKPEVQLRRPNWSK 777
Score = 57.4 bits (137), Expect = 3e-08
Identities = 49/150 (32%), Positives = 64/150 (42%), Gaps = 24/150 (16%)
Query: 13 EPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPA----LLPPPPQMLAPAFPPPLLL 68
E ++A+ E A A T P++ PAP P ++PPPP PPP
Sbjct: 545 ELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPP 604
Query: 69 PPPTGDPR-----LQPPPPLPFGLGGFPPPPGVSPA---EAAGVGEGLGLGLPS--PRGP 118
PPP P + PP LP G PPPP A + EG+G+ PS P G
Sbjct: 605 PPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGT 664
Query: 119 GLNLPPPIGGAG------PPL----GLPKP 138
+ PPP+ G+ PPL G+P P
Sbjct: 665 AIPPPPPLPGSARIPPPPPPLPGSAGIPPP 694
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 68.6 bits (166), Expect = 1e-11
Identities = 49/140 (35%), Positives = 60/140 (42%), Gaps = 11/140 (7%)
Query: 19 PEPEEEEAVAPTSGPALGGLFASLPA--PKGPALLPPPPQMLAPAFPPPLLLPPPTGDPR 76
P P +A P P G+ P+ P G A+ PPPP + PPP PP G
Sbjct: 642 PPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP--PPLPGSAG 699
Query: 77 LQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGG--AGPPLG 134
+ PPPP G G PPPP P G G+ P P GPG+ PPP G PP G
Sbjct: 700 IPPPPPPLPGEAGMPPPPPPLPG-----GPGIPPPPPFPGGPGIPPPPPGMGMPPPPPFG 754
Query: 135 LPKPKKRKEPVKIAAPELHK 154
P P + +L+K
Sbjct: 755 FGVPAAPVLPFGLTPKKLYK 774
Score = 62.4 bits (150), Expect = 9e-10
Identities = 53/151 (35%), Positives = 63/151 (41%), Gaps = 32/151 (21%)
Query: 19 PEPEEEEAVAPTSGPALGGLFASLPAPK--GPALLPPPPQMLA-----PAFPPPLL---- 67
P P E V S +L G A P P G A +PPPP L P PPPL
Sbjct: 653 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG 712
Query: 68 LPPPT----GDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLP 123
+PPP G P + PPPP P G G PPPP G+G+ P P G G+
Sbjct: 713 MPPPPPPLPGGPGIPPPPPFPGGPGIPPPPP------------GMGMPPPPPFGFGVPAA 760
Query: 124 PPIGGAGPPLGLPKPKKRKEPVKIAAPELHK 154
P + P GL K K V++ P K
Sbjct: 761 PVL-----PFGLTPKKLYKPEVQLRRPNWSK 786
Score = 57.4 bits (137), Expect = 3e-08
Identities = 49/150 (32%), Positives = 64/150 (42%), Gaps = 24/150 (16%)
Query: 13 EPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPA----LLPPPPQMLAPAFPPPLLL 68
E ++A+ E A A T P++ PAP P ++PPPP PPP
Sbjct: 554 ELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPP 613
Query: 69 PPPTGDPR-----LQPPPPLPFGLGGFPPPPGVSPA---EAAGVGEGLGLGLPS--PRGP 118
PPP P + PP LP G PPPP A + EG+G+ PS P G
Sbjct: 614 PPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGT 673
Query: 119 GLNLPPPIGGAG------PPL----GLPKP 138
+ PPP+ G+ PPL G+P P
Sbjct: 674 AIPPPPPLPGSARIPPPPPPLPGSAGIPPP 703
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 67.8 bits (164), Expect = 2e-11
Identities = 57/166 (34%), Positives = 63/166 (37%), Gaps = 32/166 (19%)
Query: 19 PEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAF----------PPPLLL 68
P P + P GP P P GP PPP Q+L P PPP+L
Sbjct: 229 PFPAGQTPPRPPLGP---------PGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLF 279
Query: 69 P------PPTGDPRLQPPPPLP-FGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLN 121
P PP G PPPP+P +G PPPP P G P P GP L
Sbjct: 280 PGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRP---PGPLGPPLT 336
Query: 122 LPPPIGGAGPPLGLPKPKKRKEPVKIAAPELHKG--DSDSEEDEPT 165
L PP GPP G P P P P + G SDS PT
Sbjct: 337 LAPPPHLPGPPPGAPPPAPHVNPA-FFPPPTNSGMPTSDSRGPPPT 381
Score = 46.6 bits (109), Expect = 5e-05
Identities = 52/160 (32%), Positives = 59/160 (36%), Gaps = 41/160 (25%)
Query: 8 SSDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLL 67
S S +A P A P G G ++P G P P P PPP
Sbjct: 177 SGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVP---GGDRFPGPA---GPGGPPP-- 228
Query: 68 LPPPTGDPRLQPPPPLPFGLGGFPPPPG------VSPAEAAG--------------VGEG 107
P P G Q PP P G G P PPG V P AG G+
Sbjct: 229 -PFPAG----QTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQP 283
Query: 108 LG---LGLPSPRGPGLNLPPPIGGAGPPLGLPKPKKRKEP 144
G LG P P GP PPP+ G GPP G P P++ P
Sbjct: 284 FGQPPLG-PLPPGP----PPPVPGYGPPPGPPPPQQGPPP 318
Score = 34.3 bits (77), Expect = 0.26
Identities = 26/62 (41%), Positives = 27/62 (43%), Gaps = 11/62 (17%)
Query: 43 PAPKGPAL-LPPPPQMLAP---AFPP-----PLLLPPPT--GDPRLQPPPPLPFGLGGFP 91
P P GP L L PPP + P A PP P PPPT G P P P G P
Sbjct: 328 PGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP 387
Query: 92 PP 93
PP
Sbjct: 388 PP 389
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 66.6 bits (161), Expect = 5e-11
Identities = 83/333 (24%), Positives = 105/333 (31%), Gaps = 34/333 (10%)
Query: 14 PDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPPPTG 73
P P P+ A P A A+LP+PKG P P + PP P P G
Sbjct: 1036 PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG---PATPSLKGAPTPPAATPPSPKG 1092
Query: 74 DPRLQPPPPLPFGLGGFPPPP--GVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGGAGP 131
P P P PP P G++ G PSP+G GL PPP G
Sbjct: 1093 GPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG-GLATPPPKGAPTT 1151
Query: 132 PLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEG--TGLSALLPQPKN 189
P P K +A P + P+ K + S +G T +A P PK
Sbjct: 1152 PAATPPSPKG----GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1207
Query: 190 --LTVKETNRLLLPHAFSRKPSDG----SPDTKPSRLASKTKTSSLAPVVGTTTTTPSPS 243
T P A P G SP P+ A+ + P P+P
Sbjct: 1208 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPP 1267
Query: 244 AIKAAAKSAALQVTKQ--------ITQEEDDSDEEVAPENFFSLPEKAEPPGVE-----P 290
A + L +T +P P A PP + P
Sbjct: 1268 AATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP 1327
Query: 291 YPYPIPTVPEELPP---GTEPEPAFQDDAANAP 320
P PT P PP GT PA + P
Sbjct: 1328 PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGP 1360
Score = 62.4 bits (150), Expect = 9e-10
Identities = 84/305 (27%), Positives = 92/305 (30%), Gaps = 37/305 (12%)
Query: 19 PEPEEEEAV-APTSGPALGGLFAS------LPAPKGPALLPPPPQMLAPAFPPPLLLPPP 71
P P+E A AP PAL +S PAPKG +P P PP P P
Sbjct: 894 PFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKG---IPASPSPKGAPTPPAATPPSP 950
Query: 72 TGDPRLQPPPPLPFGLGGFPPPPGVSPAEAA--GVGEGLGLGLPSPRGPGLNLPPPIGGA 129
G P P P PP P PA + G PSP+G G P P G
Sbjct: 951 KGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKG-GPATPSPKGAP 1009
Query: 130 GPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGLSALLPQPKN 189
PP P P + P AA KG S P K G A P PK
Sbjct: 1010 TPPAVTP-PSPKGSP---AATPFPKGASTPPAATPPSPK----------GSPAATPLPKG 1055
Query: 190 LTVKETNRLLLPHAFSRKPS-DGSPD----TKPSRLASKTKTSSLAPVVGTTTTTPSPSA 244
L P PS G+P T PS S + T PSP
Sbjct: 1056 APTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKG 1115
Query: 245 IKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPG-----VEPYPYPIPTVP 299
A T T P A PP P P PT P
Sbjct: 1116 GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175
Query: 300 EELPP 304
PP
Sbjct: 1176 AATPP 1180
Score = 62.0 bits (149), Expect = 1e-09
Identities = 91/348 (26%), Positives = 117/348 (33%), Gaps = 33/348 (9%)
Query: 14 PDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQM-LAPAFPPP-----LL 67
P P P+ A P G A+ P+PKG PPP PA PP L
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPA-ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1187
Query: 68 LPPPTGDPRLQPP-PPLPFGLGGFPPPPGV--SPAEAAGVGEGLGLGLPSPRG----PGL 120
P P G P PP P G P P G +PA +G GL PSP+G P
Sbjct: 1188 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG-GLATPSPKGAPTTPAA 1246
Query: 121 NLPPPIGGAG--PPLGLPKPKKRKEPVK---IAAPELHKGDSDSEEDEPTKKK---TILQ 172
P P GG PP G P P P +A P HKG + P K
Sbjct: 1247 TPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPP-HKGAPNPAVVTPPSPKGGPATSP 1305
Query: 173 GSSEGTGLSALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPS-RLASKTKTSSLAP 231
T +A P PK P P+ P K + L + T +S P
Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPP-----PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGP 1360
Query: 232 VVGTTTTTPSPSAIKAAAKSAALQVT---KQITQEEDDSDEEVAPENFFSLPEKAEPPGV 288
++ P+P A + K K+ + +P P+KA V
Sbjct: 1361 TTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPV 1420
Query: 289 EPYPYPIPTVPEELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMP 336
P+ + PP P + A +AP S G P +P
Sbjct: 1421 TREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLP 1468
Score = 55.8 bits (133), Expect = 8e-08
Identities = 93/343 (27%), Positives = 113/343 (32%), Gaps = 71/343 (20%)
Query: 14 PDEAEPEPEEEEAVAPTSG----PALGGLFASLPAPKGPALLPP--PPQMLAPAFP---- 63
P P P+ P G PA+ + P+PKG LP P P P
Sbjct: 1313 PAATPPSPKGSPGTPPPKGAPTPPAV-----TPPSPKGTPTLPATTPSSKGGPTTPSSKE 1367
Query: 64 ---PPLLLPPPTGDPRLQPP-----PPLPFGLGGFPPPPGVSP-----AEAAGVGEGLGL 110
PP P G P + PP P +P G P P V P A A V G
Sbjct: 1368 GPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGD-PTSPAVIPLSPKKAPATPVTRE-GA 1425
Query: 111 GLPSPRGPGLNLPPPIGGAGPPLGLPKPKKRKEPVKIAAPELHKGD------SDSEEDEP 164
PS +L PP A P+ L K P A KGD + EP
Sbjct: 1426 ATPSKG----DLTPP---AVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP 1478
Query: 165 TKKKTILQGSSEGTGLSALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSR----- 219
K + SS P+ T LP P + P T SR
Sbjct: 1479 PAPKQVATSSS---------PKKAPATPAPMGAPTLPAVIPSSPKE-VPATPSSRRDPIA 1528
Query: 220 ----LASKTKTSSLAP---VVGTTTTTPSPSAIKAAAKSAALQVTKQITQEEDDSDEEVA 272
L SK ++LAP ++ T PSP K A + + +E S V
Sbjct: 1529 PTATLLSKKTPATLAPKEALIPPAMTVPSPK--KTPAIPTPKEAPATPSSKEASSPPAVT 1586
Query: 273 PENFFSLPEKAE---PPGV-EPYPYPIPTVPEELPPGTEPEPA 311
P + P E PP V P P PT P PP E PA
Sbjct: 1587 PSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPA 1629
Score = 39.7 bits (91), Expect = 0.006
Identities = 78/323 (24%), Positives = 106/323 (32%), Gaps = 48/323 (14%)
Query: 14 PDEAEPEPEEEEAVA-PTSG----PALGGL----FASLPAPK-GPALLPPPPQMLAPAFP 63
P +A P E A P+ G PA+ + + APK GPA PA
Sbjct: 1412 PKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471
Query: 64 PPLLLPPP-------TGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGL------GL 110
PP PP + P+ P P P G P SP E
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTA 1531
Query: 111 GLPSPRGPGLNLPPPIGGAGPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTI 170
L S + P L P P + +P PKK A P + + E + +
Sbjct: 1532 TLLSKKTPA-TLAPKEALIPPAMTVPSPKKTP-----AIPTPKEAPATPSSKEASSPPAV 1585
Query: 171 LQGSSEGTGLSALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLA 230
+ +G P PK LL+P A + PS T P+ +
Sbjct: 1586 TPSTYKGA------PSPK--------ELLIPPAVT-SPSPKEAPTPPAVTPPSPEKGPAT 1630
Query: 231 PVVGTTTTTP--SPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGV 288
P T T+P +PS++K + S A K S A + +L E P
Sbjct: 1631 PAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPA- 1689
Query: 289 EPYPYPIPTVPEELPPGTEPEPA 311
P PI T P P T+ A
Sbjct: 1690 -PESTPIITAPTRKGPQTKKSSA 1711
Score = 35.8 bits (81), Expect = 0.091
Identities = 72/321 (22%), Positives = 94/321 (29%), Gaps = 40/321 (12%)
Query: 12 SEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPP---PPQMLAPAFPPP--- 65
S P E E A A + G A P+P G ++ P PP A P
Sbjct: 765 SSPKECPTEDSGASATASSKGTLT--YLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIG 822
Query: 66 -LLLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPP 124
L P + P L F P SP + G + G+ LPP
Sbjct: 823 NLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPP 882
Query: 125 PIGGAGPPLGLPKPKKRKE-PVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGL--- 180
+ LP PK+ P AP L S ++ T + S G
Sbjct: 883 KETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP 942
Query: 181 -SALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTT 239
+A P PK + + + PS PS + T ++ P T
Sbjct: 943 PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPAT 1002
Query: 240 PSPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVP 299
PSP K A A V P P P P+P T P
Sbjct: 1003 PSP---KGAPTPPA-----------------VTP------PSPKGSPAATPFPKGASTPP 1036
Query: 300 EELPPGTEPEPAFQDDAANAP 320
PP + PA AP
Sbjct: 1037 AATPPSPKGSPAATPLPKGAP 1057
Score = 35.8 bits (81), Expect = 0.091
Identities = 46/175 (26%), Positives = 65/175 (37%), Gaps = 50/175 (28%)
Query: 19 PEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFP------PPLLLPPPT 72
P+PE A S P SLP P PP Q P+ P P L P
Sbjct: 1783 PKPESASVSAAPSPPV------SLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPAD 1836
Query: 73 GDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGGAGPP 132
D L PP P GG P + + + +P+P+ G+ +P P
Sbjct: 1837 EDELLPLIPPEPIS-GGVP-------------FQSVLVNMPTPKSAGIPVPTP------- 1875
Query: 133 LGLPKPKKRKEPVKIAAPELHKG---DSDSEEDEPTKKKTILQGSSEGTGLSALL 184
K+PV + +KG +SDS+E P ++ Q S++ T A L
Sbjct: 1876 -------SAKQPV----TKNNKGSGTESDSDESVPELEE---QDSTQATTQQAQL 1916
Score = 34.7 bits (78), Expect = 0.20
Identities = 77/333 (23%), Positives = 117/333 (35%), Gaps = 56/333 (16%)
Query: 19 PEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPP--PPQMLAPAFPPPLLLPPPTGDPR 76
P+P+ E AV P S + A+L P GP L PP P P P P+
Sbjct: 17 PQPQAETAVLPMSSAL--SVTAALGQP-GPTLPPPCSPAPQQCPLSAANQASPFPSPSTI 73
Query: 77 LQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGGAGPPLGLP 136
P +PF P ++G LG +P + PPI A L P
Sbjct: 74 ASTPLEVPF------------PQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASP 121
Query: 137 KPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGL--SALLPQPKNLTVKE 194
+ AP L KG S P + S + + LL P ++ V E
Sbjct: 122 ----------MIAPTL-KGTPSS--SAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAE 168
Query: 195 TNRLLLPHAFSRKPSDGSPDTK----PSRLASKTKTSSLAPVVGTTT----TTPSPS--- 243
+ ++ S + P T PS + K + P + +T TP S
Sbjct: 169 SGSVI---TLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQS 225
Query: 244 ---AIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPE 300
++ + L + ++ S ++P+N SL K V P P + +
Sbjct: 226 GVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGP---VSP-PAALSLSTQ 281
Query: 301 ELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAP 333
LP T + + N P +F ++ GS AP
Sbjct: 282 SLPVVTSSQ---KTAGPNTPPDFPISLGSHLAP 311
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 65.9 bits (159), Expect = 8e-11
Identities = 71/254 (27%), Positives = 91/254 (35%), Gaps = 52/254 (20%)
Query: 19 PEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPPPTGDPRLQ 78
P P P PA G P + P PPPP P P + +PPP +
Sbjct: 289 PPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPP----PPSRPSVAVPPPPPNRMYP 344
Query: 79 PPPP-LPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGGAGPPLGLPK 137
PPPP LP PPPP P GVG P P P PPP G PP GLP
Sbjct: 345 PPPPALPSSAPSGPPPP---PPSVLGVGPVA----PPPPPP----PPPPPGPPPPPGLP- 392
Query: 138 PKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGLSALLPQPKNLTVKETNR 197
SD + PT +ALL Q ++E +
Sbjct: 393 -------------------SDGDHQVPTT----------AGNKAALLDQ-----IREGAQ 418
Query: 198 LLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTPSP-SAIKAAAKSAALQV 256
L SR S D ++ + S+A +T TP+P S I A +
Sbjct: 419 LKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKR 478
Query: 257 TKQITQEEDDSDEE 270
+K I ++D DE+
Sbjct: 479 SKAIHSSDEDEDED 492
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 65.5 bits (158), Expect = 1e-10
Identities = 47/145 (32%), Positives = 51/145 (35%), Gaps = 23/145 (15%)
Query: 14 PDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPPPTG 73
P A P P P P +G P P P PP P AP PPP PP
Sbjct: 318 PPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPP----PPAA 373
Query: 74 DPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGGAGPPL 133
D PPPPL GG PPPP P P GP PPP GA
Sbjct: 374 DYPTLPPPPLSQPTGGAPPPPPP----------------PPPPGPP---PPPFTGADGQP 414
Query: 134 GLPKPKKRKEPVKIAAPELHKGDSD 158
+P P K + P + SD
Sbjct: 415 AIPPPLSDTTKPKSSLPAVSDARSD 439
Score = 47.8 bits (112), Expect = 2e-05
Identities = 44/132 (33%), Positives = 55/132 (41%), Gaps = 24/132 (18%)
Query: 8 SSDESEPDEAE-PEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPL 66
S D P AE P + + + +GP +S+ +P P PP P + +P P P
Sbjct: 263 SEDNLPPPPAEFSYPVDNQRGSGLAGPKR----SSVVSPSHP---PPAPPLGSPPGPKPG 315
Query: 67 LLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPI 126
PPP PPPP P +G PPPP V G G G P P P + PP
Sbjct: 316 FAPPPA------PPPPPPPMIGIPPPPPPV------GFGSP---GTPPPPSPP-SFPPHP 359
Query: 127 GGAGPPLGLPKP 138
A PP P P
Sbjct: 360 DFAAPPPPPPPP 371
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 64.7 bits (156), Expect = 2e-10
Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 49/315 (15%)
Query: 37 GLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPPPTGDPRLQPPPPLPFGLGGFPPPPGV 96
G+ P P P PP P PPP +PPP G P LQ PP +P + PPPPG+
Sbjct: 54 GMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGM 113
Query: 97 SPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGGAGPPLGLPKPK-------------KRKE 143
G+P PG PP P K + +
Sbjct: 114 M----------FPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPD 163
Query: 144 PVK----------------IAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGLSALLPQP 187
VK + A + + ++ + + Q ++ + Q
Sbjct: 164 GVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 223
Query: 188 KNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKT-SSLAPVVGTTTTTPSPSAIK 246
+ + A ++ + + + + T T SS AP V T+T++ +PS+
Sbjct: 224 QAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTT 283
Query: 247 A---AAKSAALQVTKQITQEEDDSD--EEVAPENFFSLP-EKAEPPGVEPYPYP---IPT 297
+ A S A V+ TQ++ S P S P A P P P+P P
Sbjct: 284 STTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPA 343
Query: 298 VPEELPPGTEPEPAF 312
VP +P T PAF
Sbjct: 344 VPHSVPQPTTAIPAF 358
Score = 48.9 bits (115), Expect = 1e-05
Identities = 39/102 (38%), Positives = 46/102 (45%), Gaps = 24/102 (23%)
Query: 46 KGPALLPPPPQMLAPAFPPPLLLPPPT-GDPRLQPPPPL-PFGLGGFPP--PPGVSPAEA 101
+GPA PPP + PPPL+ PPP G R PPPP PFG F P PP P
Sbjct: 30 RGPA---PPPNAVMRG-PPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPG-- 83
Query: 102 AGVGEGLGLGLPSPRGP-----GLNLPPPIGGAGPPLGLPKP 138
G+P P GP +PPP+ PP G+ P
Sbjct: 84 ---------GIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFP 116
Score = 34.7 bits (78), Expect = 0.20
Identities = 29/82 (35%), Positives = 35/82 (42%), Gaps = 15/82 (18%)
Query: 28 APTSGPALGGLFASLPAPKGPALLP------PPPQMLAPAFPPPLLLPPPTGDPRLQPPP 81
APT+ P ++P P L P P P PAFPP ++ PP P P
Sbjct: 323 APTATPV-----QTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMV--PPFRVPLPGMPI 375
Query: 82 PLPFGLGGFPPP--PGVSPAEA 101
PLP L G PP P + P A
Sbjct: 376 PLPGVLPGMAPPIVPMIHPQVA 397
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 64.7 bits (156), Expect = 2e-10
Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 49/315 (15%)
Query: 37 GLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPPPTGDPRLQPPPPLPFGLGGFPPPPGV 96
G+ P P P PP P PPP +PPP G P LQ PP +P + PPPPG+
Sbjct: 54 GMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGM 113
Query: 97 SPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGGAGPPLGLPKPK-------------KRKE 143
G+P PG PP P K + +
Sbjct: 114 M----------FPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPD 163
Query: 144 PVK----------------IAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGLSALLPQP 187
VK + A + + ++ + + Q ++ + Q
Sbjct: 164 GVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQA 223
Query: 188 KNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKT-SSLAPVVGTTTTTPSPSAIK 246
+ + A ++ + + + + T T SS AP V T+T++ +PS+
Sbjct: 224 QAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTT 283
Query: 247 A---AAKSAALQVTKQITQEEDDSD--EEVAPENFFSLP-EKAEPPGVEPYPYP---IPT 297
+ A S A V+ TQ++ S P S P A P P P+P P
Sbjct: 284 STTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPA 343
Query: 298 VPEELPPGTEPEPAF 312
VP +P T PAF
Sbjct: 344 VPHSVPQPTTAIPAF 358
Score = 48.9 bits (115), Expect = 1e-05
Identities = 39/102 (38%), Positives = 46/102 (45%), Gaps = 24/102 (23%)
Query: 46 KGPALLPPPPQMLAPAFPPPLLLPPPT-GDPRLQPPPPL-PFGLGGFPP--PPGVSPAEA 101
+GPA PPP + PPPL+ PPP G R PPPP PFG F P PP P
Sbjct: 30 RGPA---PPPNAVMRG-PPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPG-- 83
Query: 102 AGVGEGLGLGLPSPRGP-----GLNLPPPIGGAGPPLGLPKP 138
G+P P GP +PPP+ PP G+ P
Sbjct: 84 ---------GIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFP 116
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 63.5 bits (153), Expect = 4e-10
Identities = 37/94 (39%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
Query: 15 DEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPPP--- 71
D + EP + A P P+ G+ AP P LPP P + A PPP PPP
Sbjct: 283 DSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPL 342
Query: 72 --TGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAG 103
TG P PPPPLP + PPPP P A+G
Sbjct: 343 PSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASG 376
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 63.5 bits (153), Expect = 4e-10
Identities = 37/94 (39%), Positives = 44/94 (46%), Gaps = 5/94 (5%)
Query: 15 DEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPPP--- 71
D + EP + A P P+ G+ AP P LPP P + A PPP PPP
Sbjct: 283 DSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPL 342
Query: 72 --TGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAG 103
TG P PPPPLP + PPPP P A+G
Sbjct: 343 PSTGPPPPPPPPPLPNQVPPPPPPPPAPPLPASG 376
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 62.0 bits (149), Expect = 1e-09
Identities = 87/349 (24%), Positives = 115/349 (32%), Gaps = 60/349 (17%)
Query: 11 ESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPP 70
E E + E E +EE AVA PA A K A LPPPP PPP L PP
Sbjct: 370 EEEEKDKEGEEKEERAVAEEMMPA---------AEKEEAKLPPPPLTPPAPSPPPPLPPP 420
Query: 71 PTGDPR-LQPPPPLPFG---LGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPI 126
T P L PPPP P L PPPP E + PPP+
Sbjct: 421 STSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEES--------------------PPPV 460
Query: 127 GGA------GPPLGLPKPKKRKEPVKIA-------APELHKGDSDSEEDEPT---KKKTI 170
A G P P + +E + P ED PT K T
Sbjct: 461 VPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTF 520
Query: 171 LQGSSEGTGLSALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLA 230
L+ + + ++ + +K R + + SP +P S A
Sbjct: 521 LKNIRQ--FIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPA 578
Query: 231 PVVGTTTTTPSPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEP 290
P V + P+P + + ++ T E+ P P A PP P
Sbjct: 579 P-VPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPP------PPPAPPPPPAP 631
Query: 291 YPYPIPTVPEELPPGTEPEPAFQDDAANAPL-EFKMAAGSSGAPWMPKP 338
P P P P P F A+ + E + GAP P+P
Sbjct: 632 SPPPAPATSSRRPLLLR-APQFTPSEAHLKIYESVLTPPPLGAPEAPEP 679
Score = 33.5 bits (75), Expect = 0.45
Identities = 34/113 (30%), Positives = 40/113 (35%), Gaps = 27/113 (23%)
Query: 11 ESEPDEAEPEPEEEEAVA---------PTSGPALGGLFASLPAPKGPALLPPPPQMLAPA 61
E EP A+ P E E A P P + + +P G L PQ A
Sbjct: 678 EPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQL 737
Query: 62 FPP---------PLLLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVG 105
P P LPPP P+LQPPP P + A AGVG
Sbjct: 738 LQPLQALQTQLLPQALPPP--QPQLQPPP-------SPQQMPPLEKARIAGVG 781
Score = 32.7 bits (73), Expect = 0.77
Identities = 30/92 (32%), Positives = 32/92 (34%), Gaps = 30/92 (32%)
Query: 43 PAPKGPALLPPPPQ----------MLAPAFPPP---------LLLPPPTGDPRLQPPPPL 83
PAP P PPP + AP F P +L PPP G P P
Sbjct: 623 PAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPE-- 680
Query: 84 PFGLGGFPPPPGVSPA--EAAGVGEGLGLGLP 113
PPP SPA E VG L LP
Sbjct: 681 -------PPPADDSPAEPEPRAVGRTNHLSLP 705
Score = 31.6 bits (70), Expect = 1.7
Identities = 26/82 (31%), Positives = 33/82 (40%), Gaps = 14/82 (17%)
Query: 13 EPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPPPT 72
+PD P P +P + +AS P P L PPP + A L P +
Sbjct: 1903 DPDFPAP-PRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTA------LTPTS 1955
Query: 73 GDPRLQPPPPLPFGLGGFPPPP 94
G+ L PP P P PPPP
Sbjct: 1956 GE--LAPPGPAP-----SPPPP 1970
Score = 31.2 bits (69), Expect = 2.2
Identities = 17/37 (45%), Positives = 19/37 (51%), Gaps = 9/37 (24%)
Query: 26 AVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAF 62
A+ PTSG AP GPA PPPP+ L P F
Sbjct: 1950 ALTPTSGEL---------APPGPAPSPPPPEDLGPDF 1977
Score = 30.8 bits (68), Expect = 2.9
Identities = 31/116 (26%), Positives = 37/116 (31%), Gaps = 23/116 (19%)
Query: 19 PEPEEEEAVAPTSGPALGGLFASL-----PAPKGPALLPPPPQMLAPAFPPPLLLPP--- 70
PEP + LG +F + P P P PP P ++P P LPP
Sbjct: 2181 PEPPKPATSKIILVNKLGQVFVKMAGEGEPVPP-PVKQPPLPPTISPTAPTSWTLPPGPL 2239
Query: 71 -----------PTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSP 115
P P PPPPL L P P V G P+P
Sbjct: 2240 LGVLPVVGVVRPAPPP---PPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAP 2292
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 61.6 bits (148), Expect = 2e-09
Identities = 45/129 (34%), Positives = 55/129 (42%), Gaps = 14/129 (10%)
Query: 25 EAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPPPTGDPRL------- 77
+++ T GP+ G L PA PA LP P + P PPP + PPP P
Sbjct: 448 QSMMKTEGPSYGAL---PPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTP 504
Query: 78 -QPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGGAGPPLGLP 136
PPPP + PPPP + P A GLGLP P +PP G PP+ P
Sbjct: 505 GYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPP---GGQPPVPPP 561
Query: 137 KPKKRKEPV 145
P PV
Sbjct: 562 IPPPGMPPV 570
Score = 46.2 bits (108), Expect = 7e-05
Identities = 36/98 (36%), Positives = 40/98 (40%), Gaps = 22/98 (22%)
Query: 40 ASLPAPKGPALLP---PPPQMLAPAFPPPLLLPPPTGDPRLQPPPPLPFGLGGFPP---P 93
AS P P P P PPP P FPPP PPT PPP L +PP P
Sbjct: 492 ASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVP 551
Query: 94 PGVSPAEAAGVGEGLGLGLPSP-RGPGLNLPPPIGGAG 130
PG P +P P PG+ PP+GG G
Sbjct: 552 PGGQPP------------VPPPIPPPGM---PPVGGLG 574
Score = 43.9 bits (102), Expect = 3e-04
Identities = 47/183 (25%), Positives = 66/183 (36%), Gaps = 60/183 (32%)
Query: 8 SSDESEPDEAEPE-PEEEEAVA---------PTSGPALGGLFASLPAPKGPALLPPPPQM 57
SS+ S+P + +P+ P +++ A P+S + P + A PPPP++
Sbjct: 296 SSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKI 355
Query: 58 ---------LAPAFPPP--------------------------LLLPPPTGDPRLQPPPP 82
L PA PPP + +PPP + PPP
Sbjct: 356 PKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPP 415
Query: 83 LPFGLGGFPPPP-------GVSPAEAAGVGEGLG--LGLPSPRGPGLNLPPPIGGAGPPL 133
LP PPPP G+S + GEG + GP PP GPP
Sbjct: 416 LPHR----PPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPP--AYGPPA 469
Query: 134 GLP 136
LP
Sbjct: 470 HLP 472
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/95 (31%), Positives = 36/95 (37%), Gaps = 16/95 (16%)
Query: 19 PEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQM----LAPAFPPPLL------L 68
P P + P + P + P P PPPP++ P PPP L
Sbjct: 486 PVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASY 545
Query: 69 PPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAG 103
PPP P QPP P P PPPG+ P G
Sbjct: 546 PPPAVPPGGQPPVPPPI------PPPGMPPVGGLG 574
>gi|55749531 splicing factor 3B subunit 2 [Homo sapiens]
Length = 895
Score = 61.6 bits (148), Expect = 2e-09
Identities = 41/122 (33%), Positives = 55/122 (45%), Gaps = 22/122 (18%)
Query: 47 GPALLPPPPQMLAPAFPPPLLLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGE 106
G PPP P P P PPP G P LQPPPP P PPPP
Sbjct: 75 GDKAAPPPMSAQLPGIPMP---PPPLGLPPLQPPPPPP------PPPP------------ 113
Query: 107 GLGLGLPSPRGPGLNLPPPIGGAGPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTK 166
GLGLG P P L PPP+ G P+ L + ++ K + AA + + + ++ + +
Sbjct: 114 GLGLGFPMAHPPNLGPPPPL-RVGEPVALSEEERLKLAQQQAALLMQQEERAKQQGDHSL 172
Query: 167 KK 168
K+
Sbjct: 173 KE 174
Score = 30.0 bits (66), Expect = 5.0
Identities = 53/201 (26%), Positives = 67/201 (33%), Gaps = 62/201 (30%)
Query: 15 DEAEPEPEEEEAVA-PTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFP----PPLLLP 69
D+A P P + P P LG LP + P PPPP L FP P L P
Sbjct: 76 DKAAPPPMSAQLPGIPMPPPPLG-----LPPLQPPPPPPPPPPGLGLGFPMAHPPNLGPP 130
Query: 70 PP--TGDP-------RL------------QPPPPLPFGLGGFPPPPGVSPAEAAGV---- 104
PP G+P RL Q G + + A V
Sbjct: 131 PPLRVGEPVALSEEERLKLAQQQAALLMQQEERAKQQGDHSLKEHELLEQQKRAAVLLEQ 190
Query: 105 ---GEGLGLGLPSPRGP------------GLNLPPPIGGAGP-----PLGLPKPKKRKEP 144
E +G P PR P G + P+G GP P+G P P+ R
Sbjct: 191 ERQQEIAKMGTPVPRPPQDMGQIGVRTPLGPRVAAPVGPVGPTPTVLPMGAPVPRPR--- 247
Query: 145 VKIAAPELHKGDSDSEEDEPT 165
P GD + E D+P+
Sbjct: 248 ----GPPPPPGDENREMDDPS 264
Score = 29.6 bits (65), Expect = 6.5
Identities = 57/272 (20%), Positives = 92/272 (33%), Gaps = 44/272 (16%)
Query: 16 EAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPPPTGDP 75
E E + E + P P + P GP + P + P P P +LP P
Sbjct: 189 EQERQQEIAKMGTPVPRPPQDMGQIGVRTPLGPRVAAP----VGPVGPTPTVLPMGAPVP 244
Query: 76 RLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGGAGPPLGL 135
R + P PPPPG E + P G P L
Sbjct: 245 RPRGP----------PPPPGDENRE---------------------MDDPSVGPKIPQAL 273
Query: 136 PKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSE-GTGLSALLPQPKNLTVKE 194
K + KE + E + EE E + ++ Q +SE ++ + KN +
Sbjct: 274 EKILQLKE----SRQEEMNSQQEEEEMETDARSSLGQSASETEEDTVSVSKKEKNRKRRN 329
Query: 195 TNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPV-VGTTTTTP---SPSAIKAAAK 250
+ P S+ S D + S+ S A V + T P P+ I
Sbjct: 330 RKKKKKPQRVRGVSSESSGDREKDSTRSRGSDSPAADVEIEYVTEEPEIYEPNFIFFKRI 389
Query: 251 SAALQVTKQITQEEDDSDEEVAPENFFSLPEK 282
A ++T + +E++ E++ + P+K
Sbjct: 390 FEAFKLTDDVKKEKEKEPEKLDKLENSAAPKK 421
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 60.8 bits (146), Expect = 3e-09
Identities = 89/354 (25%), Positives = 127/354 (35%), Gaps = 46/354 (12%)
Query: 17 AEPEPEEEEAVAPT--------SGPALGGLFAS---LPAPKGPALLP-PPPQMLAPAFPP 64
++P+P+ +A+ P + PALG L +S P+P G P PPP A P
Sbjct: 270 SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPA 329
Query: 65 PLLLPPPTGDP-RLQPP-PPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNL 122
L PP P L PP P P L P PP P++A PS P +
Sbjct: 330 TLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP----------PSMTTPPMQA 379
Query: 123 PPPIGGAGP---PLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKT--ILQGSSEG 177
PP + P P L P + P +A L + + PT + T L S
Sbjct: 380 PPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSL---QATTSLGSPTLQATHSFLTMSPRQ 436
Query: 178 TGLSALLPQPKNLTVKETNRLLLPHAFSRKP-------SDGSPDTKPSRLASKTKTSSLA 230
T S P T ++ L P + P SP + P + SSLA
Sbjct: 437 TQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLA 496
Query: 231 ---PVVGTTTTTPSPSAIKAAAKSAALQV-TKQITQEEDDSDEEVAPENFFSLPEKAEPP 286
P ++ P +++ +LQ +T ++ +AP + P
Sbjct: 497 SHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTP 556
Query: 287 GVEPYPYPIPTVPEELPPG--TEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKP 338
+E P P P P + PP T P P A P + A S +P P
Sbjct: 557 HLETPPCPAP-CPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP 609
Score = 54.7 bits (130), Expect = 2e-07
Identities = 77/287 (26%), Positives = 102/287 (35%), Gaps = 61/287 (21%)
Query: 8 SSDESEPDEAEPEPEEEEAVAPTSGPALGGLFASL-PAPKGPALLPPPPQMLAPAFP--- 63
S + P +A P P S PA + S P P+ P LL PP + P+ P
Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776
Query: 64 --PPLLLPPPTGDPRLQPPP--PLPFGLGGFP------------------PPPGVSPAEA 101
PL PPP P L PP LP FP PPP P A
Sbjct: 777 PMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 836
Query: 102 AGVGEGLGLGLPSPRGPGLNLP--PPIGG-----AGPPL------GLPKPKKRKEPVKIA 148
A + L + P P L P PP G +GP L G P P R ++
Sbjct: 837 APL---LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 893
Query: 149 APELHKGDSDSEEDEPTKKKTILQGSSEGTGLSALLPQPKNLTVKETNRLLLPHAFSRKP 208
P+L G S S P + L+G G A P + + + P A+SR P
Sbjct: 894 GPDL-AGHSSSATSTPEE----LRGYDSGPEGGAAASPPPDAELAACH----PAAWSRGP 944
Query: 209 --------SDGSPDTKPSRL--ASKTKTSSLAPVVGTTTTTPSPSAI 245
+ G+P P S ++ G + TP+P A+
Sbjct: 945 APPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL 991
Score = 53.1 bits (126), Expect = 6e-07
Identities = 86/362 (23%), Positives = 116/362 (32%), Gaps = 44/362 (12%)
Query: 16 EAEPEPEEEEAVAPT------SGPALGGLFASLPAPKGPA---LLPPPPQMLAPAFPPPL 66
+A P P + A P S P L + P+P P LP PP PP +
Sbjct: 313 KARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSM 372
Query: 67 LLPPPTGDPRLQPPPPL--PFGLGGFPPPPGVSPAEAAGVGEGLGLGLP----------- 113
PP P LQ PP+ P L SP + + LG P
Sbjct: 373 TTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTM 432
Query: 114 SPRGPGLNLPPPIGGA-----GPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKK 168
SPR +L P A PPL P P++ + S P +
Sbjct: 433 SPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL 492
Query: 169 TILQGSSEGTGLSALLPQPKNLTVKETNRLLLPHAFSRKPSDGSP---DTKPSRLASKTK 225
+ L S LS+L+ P ET L P + P+ + + PS +
Sbjct: 493 SSLASHSPQAPLSSLIMPP-----LETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQ 547
Query: 226 TSSLAPVVGTTTTTPSPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEP 285
T+S T P P+ A + L T + AP S P + P
Sbjct: 548 TASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLP 607
Query: 286 -PGVEPYPYPIPTVPEEL-------PPGTEPEPAFQDDAANAP-LEFKMAAGSSGAPWMP 336
P + P P P P L PP P A +P +A AP+ P
Sbjct: 608 SPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 667
Query: 337 KP 338
P
Sbjct: 668 PP 669
Score = 49.7 bits (117), Expect = 6e-06
Identities = 85/342 (24%), Positives = 108/342 (31%), Gaps = 44/342 (12%)
Query: 17 AEPEPEEEEAVA----------PTSGPALGGLFASLPAPKGPALLPP---PPQMLAPAF- 62
A P P+ A+A P S P P P+ PP PP + AP
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 705
Query: 63 --PPPLLLPP--PTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGP 118
P P PP P+ P Q PPPL PP P SP + P PR P
Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPS-------ATPPPRVP 758
Query: 119 GLNLPPPIG-GAGPPLGLPKPKKRKEPVK----IAAPELHKGDSDSEE---DEPTKKKTI 170
L PP+ PP LP K P + +A P L S P
Sbjct: 759 PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 818
Query: 171 LQGSSEGTGLSALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLA 230
L S T P P+ V L +P + P+ +P P+ TS
Sbjct: 819 LPMSPLAT------PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT---PGPDTSVSG 869
Query: 231 PVVGTTTTTPSPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEP 290
P + T P P + + S+ L + + S PE P
Sbjct: 870 PRL-TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 928
Query: 291 YPYPIPTVPEELPPGTEPEPAFQDDAANAPLEFKMAAGSSGA 332
P G P AF+ A APL + A G A
Sbjct: 929 DAELAACHPAAWSRGPAPPLAFR-GAPGAPLPWPPATGPGSA 969
Score = 47.4 bits (111), Expect = 3e-05
Identities = 52/172 (30%), Positives = 60/172 (34%), Gaps = 53/172 (30%)
Query: 19 PEPEEEEAVA---PTSGPALGGL-FASLPAPKGPALLPPPPQMLAPAFPPPLLLPP---- 70
P PE ++A P + PAL LP+P L PPPQ PP L LPP
Sbjct: 579 PPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA-----PPXLALPPLQAP 633
Query: 71 --PTGDPRLQP----------------------PPPLPFGLGGFPPP--PGVSPAEAAGV 104
P P L P PPP P F PP P VSP+
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP-- 691
Query: 105 GEGLGLGLPSPRGPGLNLP----PPIGGAGPPLGLPKPKKRKEPVKIAAPEL 152
PS P L P PP A PP+ + P +AAP L
Sbjct: 692 --------PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 735
Score = 43.9 bits (102), Expect = 3e-04
Identities = 79/328 (24%), Positives = 115/328 (35%), Gaps = 59/328 (17%)
Query: 34 ALGGLFASLPAPKGPALLPPPPQMLAPAFPPP-----LLLPPPTGDPRLQPPPPLPFGLG 88
A G A PA + P LL P P +P PPP L + G +P G+G
Sbjct: 8 AKAGAAARTPAARAPGLLTPRPPG-SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66
Query: 89 GFPPP---PGVSPAEAAGVGEGLGLGLPSPRGPGLNLPP-------PIGGAGPPLGLPKP 138
G P P P +AG P G G PP P+ G G +P
Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126
Query: 139 -KKRKEPVKIAAPE-LHKGDS---------------DSEEDEPTKKKTILQGSSEGTGLS 181
++ ++I+A E + +G + D+ P + S G
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
Query: 182 ALLPQP--------------KNLTVKETNRLLLPH-AFSRKPSDGSPDTKP---SRLASK 223
LP+P K+++ + P A R+PS G +P S +S
Sbjct: 187 VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 246
Query: 224 TKTSSLAPVVGTTTTTPSPSAIKAAAKSAALQVTK--QITQEEDDSDEEVAPENFFSLPE 281
T SS A + TP A + K LQ + Q+T D+ + P + L
Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306
Query: 282 KAEPPGVEPYPYPIP-----TVPEELPP 304
+ P G + P P P +P LPP
Sbjct: 307 PS-PSGTKARPVPPPDNAATPLPATLPP 333
Score = 43.9 bits (102), Expect = 3e-04
Identities = 68/317 (21%), Positives = 98/317 (30%), Gaps = 40/317 (12%)
Query: 26 AVAPTSGPALGGLFASLPAPKGPALLPP---------------PPQMLAPAFPPPLLLPP 70
A P S P G ++ + + PA PP P + +P P
Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 127
Query: 71 PTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGGAG 130
P G L+ G P S A + G P+P P + AG
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG---PTPGTPSPAMARRSRAAG 184
Query: 131 PPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGLSALLPQPKNL 190
+GLP+P P S SE + S G GL +P +
Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ----RPASR 240
Query: 191 TVKETNRLLLPHAFSRKPSDGSP-------DTKPSRLAS----------KTKTSSLAPVV 233
++ + L A S + G+P KP L + K +L P+
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
Query: 234 GTTTTTPSPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPY 293
+ TPSPS KA + S P + P + PP ++ P
Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP-LAPPSPSAPPSLQTLPS 359
Query: 294 PIPTVPEELPPGTEPEP 310
P T P + PP P
Sbjct: 360 PPATPPSQAPPSMTTPP 376
Score = 43.5 bits (101), Expect = 4e-04
Identities = 46/156 (29%), Positives = 53/156 (33%), Gaps = 36/156 (23%)
Query: 14 PDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPPPTG 73
P +A P P T P A+ P PAL PP Q L PL PPP
Sbjct: 568 PLQAPPSP------LTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA 621
Query: 74 DPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPG------LNLP---- 123
P L PP L P PP P L PSP+ P L P
Sbjct: 622 PPXLALPP-----LQAPPSPPASPPLSP--------LATPSPQAPNALAVHLLQAPFSPP 668
Query: 124 --PPIGG-----AGPPLGLPKPKKRKEPVKIAAPEL 152
PP+ A PP+ + P +AAP L
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 704
Score = 35.4 bits (80), Expect = 0.12
Identities = 41/130 (31%), Positives = 47/130 (36%), Gaps = 24/130 (18%)
Query: 3 LVAYASSDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPA--PKGPALLPPPPQMLAP 60
L ++SS S P+E E A S P L A PA +GPA PP
Sbjct: 897 LAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA----PPLAFRG 952
Query: 61 AFPPPLLLPPPTG--------------DPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGE 106
A PL PP TG P P P G P PG S +AA G
Sbjct: 953 APGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG---PSPGTSGGKAA-AGA 1008
Query: 107 GLGLGLPSPR 116
G G SP+
Sbjct: 1009 GAGASSRSPK 1018
>gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]
Length = 1096
Score = 60.1 bits (144), Expect = 5e-09
Identities = 56/164 (34%), Positives = 69/164 (42%), Gaps = 31/164 (18%)
Query: 7 ASSDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPL 66
A ++ + DE E E E T L +S GP PP P + P PPP
Sbjct: 514 AQAELQKRDEKIKELEAEIQQLRTQAQVL----SSSSGIPGPPAAPPLPGVGPP--PPPP 567
Query: 67 LLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPI 126
P P G P PPPPLP G+ G PPPP L G P P PPP+
Sbjct: 568 APPLPGGAPLPPPPPPLP-GMMGIPPPPPPP----------LLFGGPPP-------PPPL 609
Query: 127 GGAGPP----LGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTK 166
GG PP L LP K+K K+ PE+ + + EPT+
Sbjct: 610 GGVPPPPGISLNLPYGMKQK---KMYKPEVSMKRINWSKIEPTE 650
>gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]
Length = 1101
Score = 60.1 bits (144), Expect = 5e-09
Identities = 56/164 (34%), Positives = 69/164 (42%), Gaps = 31/164 (18%)
Query: 7 ASSDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPL 66
A ++ + DE E E E T L +S GP PP P + P PPP
Sbjct: 514 AQAELQKRDEKIKELEAEIQQLRTQAQVL----SSSSGIPGPPAAPPLPGVGPP--PPPP 567
Query: 67 LLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPI 126
P P G P PPPPLP G+ G PPPP L G P P PPP+
Sbjct: 568 APPLPGGAPLPPPPPPLP-GMMGIPPPPPPP----------LLFGGPPP-------PPPL 609
Query: 127 GGAGPP----LGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTK 166
GG PP L LP K+K K+ PE+ + + EPT+
Sbjct: 610 GGVPPPPGISLNLPYGMKQK---KMYKPEVSMKRINWSKIEPTE 650
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
[Homo sapiens]
Length = 1125
Score = 60.1 bits (144), Expect = 5e-09
Identities = 49/137 (35%), Positives = 63/137 (45%), Gaps = 26/137 (18%)
Query: 7 ASSDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLA---PAFP 63
A + +EP P+P V P PA ++P P+ P P PP + A PAF
Sbjct: 647 AETSHTEPVSPIPKPLPVP-VPPIPVPAP----ITVPPPQVPPHQPGPPVVGALQPPAFT 701
Query: 64 PPLLLPPPTGDPRL-QPPPPLPFGLGGFPP---PPGVSPAEAAGVGEGLGLGLPSPRGPG 119
PPL +PPP P + PPPP PF GF P PPG P G P P P
Sbjct: 702 PPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPP-----------GPPPPITPP 750
Query: 120 LNLPPPIGGAGPPLGLP 136
+++PPP PP+ +P
Sbjct: 751 VSIPPP---HTPPISIP 764
Score = 51.6 bits (122), Expect = 2e-06
Identities = 56/192 (29%), Positives = 72/192 (37%), Gaps = 29/192 (15%)
Query: 9 SDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLL 68
SD PD + E VA G P PK P +P PP + P P+ +
Sbjct: 623 SDTLNPDWKGIPKKPENEVAQNGGAETSHTEPVSPIPK-PLPVPVPPIPV----PAPITV 677
Query: 69 PPPTGDPRLQPPPPLPFGL--GGFPPPPGVSPAEAAGVGEGLGLGLPSPRGP-------- 118
PPP P QP PP+ L F PP G+ P G G G+P P P
Sbjct: 678 PPPQVPPH-QPGPPVVGALQPPAFTPPLGIPP-------PGFGPGVPPPPPPPPFLRPGF 729
Query: 119 -GLNLPPPIGGAGPPLGLPKPKKRKEP--VKIAAPELHKGDSDSEEDEPTKKKTILQGSS 175
++LPP GPP + P P I+ P L G + E + K + GS+
Sbjct: 730 NPMHLPPGFLPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVK---MYGSA 786
Query: 176 EGTGLSALLPQP 187
LP P
Sbjct: 787 VPPAAPTNLPTP 798
Score = 40.4 bits (93), Expect = 0.004
Identities = 45/189 (23%), Positives = 60/189 (31%), Gaps = 47/189 (24%)
Query: 14 PDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQ--MLAPAF--------- 62
P + P V PA P GP + PPPP L P F
Sbjct: 679 PPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGF 738
Query: 63 ----PPPLLLPPPTGDPRLQPPPPLPFGLGG-------------------------FPPP 93
PPP + PP + P PP +P + G P P
Sbjct: 739 LPPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTP 798
Query: 94 PGVSPAE---AAGVGEGLGLGLPSPRGPGLNLPPPIGGAGPPLGLPKPKKRKEPVKIAAP 150
P P GV G +GL +P L P + P G+P P ++ P+ P
Sbjct: 799 PVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRP 858
Query: 151 ----ELHKG 155
+H+G
Sbjct: 859 MPPHMMHRG 867
Score = 37.4 bits (85), Expect = 0.031
Identities = 42/159 (26%), Positives = 58/159 (36%), Gaps = 42/159 (26%)
Query: 25 EAVAPTSGPALGGLFASLPAPKGPALLPPP---PQMLAPAFPPPLLLPPPTGDPRLQPPP 81
+ VAP GP +G L AP L P P P PPP L P L PP
Sbjct: 810 QGVAP--GPVIG-----LQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFP-----LMPPR 857
Query: 82 PLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLP-----------PPIGGAG 130
P+P + PPPG G +P P G P P +GG G
Sbjct: 858 PMPPHMMHRGPPPGPG-----------GFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPG 906
Query: 131 PPLGLPKPKKRK-----EPVKIAAPELHKGDSDSEEDEP 164
P G P+ + + +P + P+ + ++ +P
Sbjct: 907 PGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQP 945
Score = 36.2 bits (82), Expect = 0.070
Identities = 38/132 (28%), Positives = 51/132 (38%), Gaps = 12/132 (9%)
Query: 11 ESEPDEAEPEPEEEEAVAPTSGPALG---GLFASLPAPKGPALLPPPPQMLAPAFP-PPL 66
+ EP+ E +E+ T+ PA A++PA PA PPP FP +
Sbjct: 268 DDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGM 327
Query: 67 LLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLP--P 124
P T + P G+ P V P G G GL LP+P P + P P
Sbjct: 328 QQPAYTQHQNMDQFQPRMMGIQQDPMHHQV-PLPPNGQMPGFGL-LPTPPFPPMAQPVIP 385
Query: 125 PIGGAGPPLGLP 136
P PP+ P
Sbjct: 386 PT----PPVQQP 393
>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
[Homo sapiens]
Length = 1132
Score = 60.1 bits (144), Expect = 5e-09
Identities = 49/137 (35%), Positives = 63/137 (45%), Gaps = 26/137 (18%)
Query: 7 ASSDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLA---PAFP 63
A + +EP P+P V P PA ++P P+ P P PP + A PAF
Sbjct: 632 AETSHTEPVSPIPKPLPVP-VPPIPVPAP----ITVPPPQVPPHQPGPPVVGALQPPAFT 686
Query: 64 PPLLLPPPTGDPRL-QPPPPLPFGLGGFPP---PPGVSPAEAAGVGEGLGLGLPSPRGPG 119
PPL +PPP P + PPPP PF GF P PPG P G P P P
Sbjct: 687 PPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPP-----------GPPPPITPP 735
Query: 120 LNLPPPIGGAGPPLGLP 136
+++PPP PP+ +P
Sbjct: 736 VSIPPP---HTPPISIP 749
Score = 37.4 bits (85), Expect = 0.031
Identities = 42/159 (26%), Positives = 58/159 (36%), Gaps = 42/159 (26%)
Query: 25 EAVAPTSGPALGGLFASLPAPKGPALLPPP---PQMLAPAFPPPLLLPPPTGDPRLQPPP 81
+ VAP GP +G L AP L P P P PPP L P L PP
Sbjct: 817 QGVAP--GPVIG-----LQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFP-----LMPPR 864
Query: 82 PLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLP-----------PPIGGAG 130
P+P + PPPG G +P P G P P +GG G
Sbjct: 865 PMPPHMMHRGPPPGPG-----------GFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPG 913
Query: 131 PPLGLPKPKKRK-----EPVKIAAPELHKGDSDSEEDEP 164
P G P+ + + +P + P+ + ++ +P
Sbjct: 914 PGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQP 952
Score = 36.2 bits (82), Expect = 0.070
Identities = 38/132 (28%), Positives = 51/132 (38%), Gaps = 12/132 (9%)
Query: 11 ESEPDEAEPEPEEEEAVAPTSGPALG---GLFASLPAPKGPALLPPPPQMLAPAFP-PPL 66
+ EP+ E +E+ T+ PA A++PA PA PPP FP +
Sbjct: 253 DDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGM 312
Query: 67 LLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLP--P 124
P T + P G+ P V P G G GL LP+P P + P P
Sbjct: 313 QQPAYTQHQNMDQFQPRMMGIQQDPMHHQV-PLPPNGQMPGFGL-LPTPPFPPMAQPVIP 370
Query: 125 PIGGAGPPLGLP 136
P PP+ P
Sbjct: 371 PT----PPVQQP 378
Score = 32.0 bits (71), Expect = 1.3
Identities = 46/211 (21%), Positives = 61/211 (28%), Gaps = 69/211 (32%)
Query: 14 PDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQ--MLAPAF--------- 62
P + P V PA P GP + PPPP L P F
Sbjct: 664 PPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGF 723
Query: 63 ----PPPLLLPPPTGDPRLQPP----------------------PPLPFGLGG------- 89
PPP + PP + P PP P+P + G
Sbjct: 724 LPPGPPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAES 783
Query: 90 ------------------FPPPPGVSPAE---AAGVGEGLGLGLPSPRGPGLNLPPPIGG 128
P PP P GV G +GL +P L P +
Sbjct: 784 GDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIP 843
Query: 129 AGPPLGLPKPKKRKEPVKIAAP----ELHKG 155
P G+P P ++ P+ P +H+G
Sbjct: 844 LQRPPGMPPPHLQRFPLMPPRPMPPHMMHRG 874
>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
[Homo sapiens]
Length = 1147
Score = 60.1 bits (144), Expect = 5e-09
Identities = 49/137 (35%), Positives = 63/137 (45%), Gaps = 26/137 (18%)
Query: 7 ASSDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLA---PAFP 63
A + +EP P+P V P PA ++P P+ P P PP + A PAF
Sbjct: 647 AETSHTEPVSPIPKPLPVP-VPPIPVPAP----ITVPPPQVPPHQPGPPVVGALQPPAFT 701
Query: 64 PPLLLPPPTGDPRL-QPPPPLPFGLGGFPP---PPGVSPAEAAGVGEGLGLGLPSPRGPG 119
PPL +PPP P + PPPP PF GF P PPG P G P P P
Sbjct: 702 PPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPP-----------GPPPPITPP 750
Query: 120 LNLPPPIGGAGPPLGLP 136
+++PPP PP+ +P
Sbjct: 751 VSIPPP---HTPPISIP 764
Score = 37.4 bits (85), Expect = 0.031
Identities = 42/159 (26%), Positives = 58/159 (36%), Gaps = 42/159 (26%)
Query: 25 EAVAPTSGPALGGLFASLPAPKGPALLPPP---PQMLAPAFPPPLLLPPPTGDPRLQPPP 81
+ VAP GP +G L AP L P P P PPP L P L PP
Sbjct: 832 QGVAP--GPVIG-----LQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFP-----LMPPR 879
Query: 82 PLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLP-----------PPIGGAG 130
P+P + PPPG G +P P G P P +GG G
Sbjct: 880 PMPPHMMHRGPPPGPG-----------GFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPG 928
Query: 131 PPLGLPKPKKRK-----EPVKIAAPELHKGDSDSEEDEP 164
P G P+ + + +P + P+ + ++ +P
Sbjct: 929 PGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQP 967
Score = 36.2 bits (82), Expect = 0.070
Identities = 38/132 (28%), Positives = 51/132 (38%), Gaps = 12/132 (9%)
Query: 11 ESEPDEAEPEPEEEEAVAPTSGPALG---GLFASLPAPKGPALLPPPPQMLAPAFP-PPL 66
+ EP+ E +E+ T+ PA A++PA PA PPP FP +
Sbjct: 268 DDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGM 327
Query: 67 LLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLP--P 124
P T + P G+ P V P G G GL LP+P P + P P
Sbjct: 328 QQPAYTQHQNMDQFQPRMMGIQQDPMHHQV-PLPPNGQMPGFGL-LPTPPFPPMAQPVIP 385
Query: 125 PIGGAGPPLGLP 136
P PP+ P
Sbjct: 386 PT----PPVQQP 393
Score = 32.0 bits (71), Expect = 1.3
Identities = 46/211 (21%), Positives = 61/211 (28%), Gaps = 69/211 (32%)
Query: 14 PDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQ--MLAPAF--------- 62
P + P V PA P GP + PPPP L P F
Sbjct: 679 PPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGF 738
Query: 63 ----PPPLLLPPPTGDPRLQPP----------------------PPLPFGLGG------- 89
PPP + PP + P PP P+P + G
Sbjct: 739 LPPGPPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAES 798
Query: 90 ------------------FPPPPGVSPAE---AAGVGEGLGLGLPSPRGPGLNLPPPIGG 128
P PP P GV G +GL +P L P +
Sbjct: 799 GDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIP 858
Query: 129 AGPPLGLPKPKKRKEPVKIAAP----ELHKG 155
P G+P P ++ P+ P +H+G
Sbjct: 859 LQRPPGMPPPHLQRFPLMPPRPMPPHMMHRG 889
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 60.1 bits (144), Expect = 5e-09
Identities = 50/163 (30%), Positives = 61/163 (37%), Gaps = 29/163 (17%)
Query: 8 SSDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFP-PPL 66
S D+ E D + E E++ G + + P PP Q+ AP P PP
Sbjct: 353 SEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPP 412
Query: 67 LLPPPT------------------GDPRLQPPPPLPFGLGGFP------PPPGVSPAEAA 102
L PPP G P PP +P G P PPPG P
Sbjct: 413 LGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPP 472
Query: 103 GVGEGLGLGLPSPRGPGLNLPPPIGGAGPPLGLPKPKKRKEPV 145
G GL G P PRGP LPPP PP P+P + P+
Sbjct: 473 GPPPGLPPG-PPPRGPPPRLPPPAPPGIPP---PRPGMMRPPL 511
Score = 56.6 bits (135), Expect = 5e-08
Identities = 66/220 (30%), Positives = 84/220 (38%), Gaps = 44/220 (20%)
Query: 7 ASSDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPAL-LPPPPQMLAPAF--- 62
ASS + P ++ P P + +A P LG A P GP LPP P AP F
Sbjct: 386 ASSQQQAPPQSVP-PSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRP 444
Query: 63 --------PPPLLLPP----------PTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGV 104
P P LLPP P G P PP P P G PPP + P G+
Sbjct: 445 PGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRG-----PPPRLPPPAPPGI 499
Query: 105 GEGLGLGLPSPRGPGLNLPPPIGGAGP-PLGLPKPKKRKEPVKIAAP----ELHKGDSDS 159
P PR PG+ PP + GP P GL P P ++AP + K D S
Sbjct: 500 --------PPPR-PGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTS 550
Query: 160 EEDEPTKKKTILQGSSEGTGLSALLPQ--PKNLTVKETNR 197
K + + T A + + P L V+ N+
Sbjct: 551 AATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENK 590
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 59.7 bits (143), Expect = 6e-09
Identities = 45/127 (35%), Positives = 52/127 (40%), Gaps = 18/127 (14%)
Query: 12 SEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPK---GPALLPPPPQMLAPAFPPPLLL 68
S +A P P P LG L + P P GP L PPPP PPPL
Sbjct: 639 SNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPP------PPPLPP 692
Query: 69 PPPTGDPRLQPPPPL--------PFGLGGFPPPPGVSPAEAAGVGEGLGLGLPS-PRGPG 119
P G P PPPPL P G PPPPG++P G+ GLG PR P
Sbjct: 693 PSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPA 752
Query: 120 LNLPPPI 126
+ P+
Sbjct: 753 IEPSCPM 759
Score = 53.1 bits (126), Expect = 6e-07
Identities = 36/94 (38%), Positives = 42/94 (44%), Gaps = 9/94 (9%)
Query: 41 SLPAPKGPALLPPPPQM---LAPAFPPPLLLPPPTGDPRLQPPPP----LPFGLGGFPPP 93
+LP P PA +PPPP + L P P + P G P PPPP P G PPP
Sbjct: 644 ALPPP--PASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPP 701
Query: 94 PGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIG 127
P P + G P+P PGL PPP G
Sbjct: 702 PPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPG 735
Score = 52.8 bits (125), Expect = 7e-07
Identities = 41/116 (35%), Positives = 44/116 (37%), Gaps = 10/116 (8%)
Query: 51 LPPPPQMLAPAFPPPLLLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGL 110
LPPPP + P PPPL P+G L P PP+P G P PP P G
Sbjct: 645 LPPPPASIPP--PPPL----PSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGP 698
Query: 111 GLPSPRGPGLNLPPPIGGAGPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTK 166
P P P N P P GPP P P P P L G S P K
Sbjct: 699 PPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPP----PPGLFFGLGSSSSQCPRK 750
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 59.3 bits (142), Expect = 8e-09
Identities = 84/347 (24%), Positives = 123/347 (35%), Gaps = 57/347 (16%)
Query: 14 PDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPPPTG 73
P+E+ P EE+ PTS P P+ L PPP ++ A P L L P
Sbjct: 444 PEESPLSPPPEES--PTS-----------PPPEASRLSPPPEELPASPLPEALHLSRPLE 490
Query: 74 DPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGGAGPPL 133
+ L PPP PPP SP E L P P L P+ + PP
Sbjct: 491 ESPLSPPPE----ESPLSPPPESSPFSPL---EESPLSPPEESPPSPALETPL--SPPPE 541
Query: 134 GLP-KPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGLSALLPQPKNLTV 192
P P + P+ S E+ PT S S + P P+ +
Sbjct: 542 ASPLSPPFEESPL-----------SPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPM 590
Query: 193 K---ETNRLLLPHAFSRKPSDGSPDTKP-------SRLASKTKTSSLAPVVGTTTTTPSP 242
E +RL P F P P+ P SRL+ + S ++P + +P P
Sbjct: 591 SPPPEASRLFPP--FEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPP 648
Query: 243 SAIKAAAKSAALQVTKQITQEEDDSDEEVAPENF-FSLPEKAEPPGVEPYPYPIPTVPEE 301
++ + L V +++ ++S PE S P +A P P PE+
Sbjct: 649 E----VSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPED 704
Query: 302 LPPGTEPE------PAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDY 342
P PE P + P E ++ S G P+P + +
Sbjct: 705 SPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPH 751
Score = 59.3 bits (142), Expect = 8e-09
Identities = 92/370 (24%), Positives = 123/370 (33%), Gaps = 64/370 (17%)
Query: 9 SDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPP--- 65
S E P PEE P L F P L PPP + +P PPP
Sbjct: 573 SPPPEESPMSPPPEESPMSPPPEASRLFPPFEESP------LSPPPEE--SPLSPPPEAS 624
Query: 66 LLLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPP 125
L PPP P PP P PPP VS V L P P L+ PP
Sbjct: 625 RLSPPPEDSPMSPPPEESPMS-----PPPEVSRLSPLPVVSRLS---PPPEESPLSPPPE 676
Query: 126 IGGAGPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDE------------PTKKKTILQG 173
PP + E + P S ED P ++ L
Sbjct: 677 ESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCP 736
Query: 174 SSEGTGLSALLPQPKNLTVKETNRLLLPHA----FSRKPSDG------------------ 211
SEG LS P+ +L+ + L P A S +P +
Sbjct: 737 RSEGPHLSP-RPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGP 795
Query: 212 --SPDTKPSRLASKTKTSSLAPVVGTTTTTPSPSAIKAAAKSAALQVTKQITQEEDDSDE 269
SP + L+ +T+ L+PV +P P + +S ++ + EE
Sbjct: 796 HLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPR--PEESHLSP 853
Query: 270 EVAPENFFSLPEK-AEPPGVEPYPYPIPTVPEELPPGTEP---EPAFQD--DAANAPLEF 323
E+ PEK E PG P P +P P P P EPA + + +PL
Sbjct: 854 ELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPE 913
Query: 324 KMAAGSSGAP 333
++ SG P
Sbjct: 914 ELPLSPSGEP 923
Score = 52.8 bits (125), Expect = 7e-07
Identities = 90/364 (24%), Positives = 126/364 (34%), Gaps = 58/364 (15%)
Query: 12 SEPDEAEPEPEEEEAV-APTSGPALGGLFASLPA-----------PKGPALLPPPPQMLA 59
S P+ + +E +A+ G GG S+ P G A + PQ+ A
Sbjct: 373 SPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEA 432
Query: 60 PAFPPPLLLPPPTGDPRLQPPPPLPFG----LGGFPPPPGVSPAEAAGVGEGLGLGLPSP 115
P LLPPP P PP P PPP P A+ + E L L P
Sbjct: 433 PLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELP--ASPLPEALHLSRPLE 490
Query: 116 RGPGLNLPPPIGGAGPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSS 175
P L+ PP PP P E ++ PE E +T L
Sbjct: 491 ESP-LSPPPEESPLSPP-PESSPFSPLEESPLSPPE--------ESPPSPALETPLSPPP 540
Query: 176 EGTGL------SALLPQPKNLTVK---ETNRLLLP---HAFSRKPSDG--SPDTKPSRLA 221
E + L S L P P+ L E +RL P S P + SP + SRL
Sbjct: 541 EASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLF 600
Query: 222 SKTKTSSLAPVVGTTTTTPSPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPE 281
+ S L+P + +P P A + + ++ + EV+ + +
Sbjct: 601 PPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS 660
Query: 282 KAEPPGVEPYPYPIPTVPEELPPGTEPE-----PAFQDDAANAPLEFKMAAGSSGAPWMP 336
+ PP P P+ PEE P PE P +D + P E +P P
Sbjct: 661 RLSPP---PEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPE--------DSPASP 709
Query: 337 KPGD 340
P D
Sbjct: 710 PPED 713
Score = 51.2 bits (121), Expect = 2e-06
Identities = 76/334 (22%), Positives = 111/334 (33%), Gaps = 43/334 (12%)
Query: 12 SEPDEAEPEPEEEEAVAPT-SGPALGGLFASLPAPKGPALLPP-PPQMLAPAFPPPL--- 66
S P+E+ P P E ++P L F P P LP PP + PPP
Sbjct: 521 SPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESP 580
Query: 67 LLPPPTGDPRLQPPPPL-----PFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLN 121
+ PPP P + PPP PF PPP SP L P P ++
Sbjct: 581 MSPPPEESP-MSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLS---PPPEDSPMS 636
Query: 122 LPPPIGGAGPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGLS 181
PP PP + + +++ P S E+ PT S S
Sbjct: 637 PPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDS 696
Query: 182 ALLPQPK-------------NLTVKETNRLLLPHAFSRKP-SDG---SPDTKPSRLASKT 224
P P+ +L ++E+ L LP P S+G SP + L+ +
Sbjct: 697 PTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRP 756
Query: 225 KTSSLAPVVGTTTTTPSPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAE 284
+ L+P +P P A+ ++ + + PE P+ E
Sbjct: 757 EEPHLSPQAEEPHLSPQPE----EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEE 812
Query: 285 P--------PGVEPYPYPIPTVPEELPPGTEPEP 310
P P + P P P+ P P P
Sbjct: 813 PHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRP 846
Score = 45.8 bits (107), Expect = 9e-05
Identities = 101/402 (25%), Positives = 143/402 (35%), Gaps = 69/402 (17%)
Query: 11 ESEPDEAE--PEPEEEEAVAPTSGPALGGLFA--SLPAPKGPALLPPPPQM--------- 57
E P+E P PEE P P+L L +L P P L P P ++
Sbjct: 865 EKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPS 924
Query: 58 LAPAFPPPLLLPPPTGDPRLQPPPPLPFGLGGFPPP---PGVSPAEAAGVGEGLGLGLPS 114
L+P PP LPPP PP LG P G S E+ L +
Sbjct: 925 LSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISP 984
Query: 115 PRGPGLNLPPPIGGAGPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGS 174
P P P+ PP+ L P PV A+P L E P + +LQ S
Sbjct: 985 PPEANCTDPEPV----PPMIL--PPSPGSPVGPASPIL-------MEPLPPQCSPLLQHS 1031
Query: 175 SEGTGLSALLPQ--PKNLTVKETNRLLLPHAFS--RKPSDGSPDTKPSRLASKTKTSSLA 230
L+PQ P + L +P S K S + + + ++ +
Sbjct: 1032 --------LVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPEC 1083
Query: 231 PVVGTTTTTPSPS-----AIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEP 285
P + + T+P PS + A + + AL + ++ D AP S PE +
Sbjct: 1084 PALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPG---SQPEPGQT 1140
Query: 286 PG---VEPYPYPIPTVPEELPPGTEPE---PAFQDDAANAPLEFKMAAGSSGAPWMPKPG 339
PG E P+ PEEL P T E Q +P E + + AP P
Sbjct: 1141 PGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLI 1200
Query: 340 DDYSYNQFS--TYGDANAAGAYYQDYYSGGYYPAQDPALVPP 379
N+ S + GDA+A+ +P +P L P
Sbjct: 1201 KSDIVNEISNLSQGDASAS------------FPGSEPLLGSP 1230
Score = 43.5 bits (101), Expect = 4e-04
Identities = 31/97 (31%), Positives = 38/97 (39%), Gaps = 13/97 (13%)
Query: 32 GPALGGL--FASLPAPKGPALLPPPPQMLA--PAFPPPLLLPPPTGDPRLQPPPPLPFGL 87
GP G L + P P+GP LP PP L+ P P PPP+ + P LP
Sbjct: 4268 GPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPS 4327
Query: 88 GGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPP 124
P + P G P P+GP L PP
Sbjct: 4328 SQLPTEAQLPPTHP---------GTPKPQGPTLEPPP 4355
Score = 40.8 bits (94), Expect = 0.003
Identities = 103/442 (23%), Positives = 145/442 (32%), Gaps = 100/442 (22%)
Query: 21 PEEEEAVAPTSGPALGGLFASLPA----PKGPALLPPPPQML-APAFPPPL--------- 66
P + A P+ P GL + P P P PP P APA PP L
Sbjct: 2164 PPQVPAQVPSQDPF--GLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAG 2221
Query: 67 ----LLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNL 122
P G PR QP P PF P ++ E+ GVG G L
Sbjct: 2222 QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGG-------KASEPLLS 2274
Query: 123 PPPIGGAGPPLGLPKPKKRKEPVKIAAPELHKGDSDS--------EEDEP-------TKK 167
PPP G + L + K + P L DS S E P T +
Sbjct: 2275 PPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPR 2334
Query: 168 KTILQGSSEGTGL--------SALLPQ-PKNLTVKETNRLLLPHA---FSRKPSDGSPD- 214
+ ++ S G GL AL P P + + P+A + +P P+
Sbjct: 2335 ASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPES 2394
Query: 215 -------TKPSRLASKTKTSSLAPVVGTTTTTPSPSAIKAAAKSAALQVTKQITQEEDDS 267
+ PS S+ S + + TP P + +A S VT + + S
Sbjct: 2395 CCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPS---PVTPRFQSPDPYS 2451
Query: 268 DEEVAPEN---FFSL--PEKAEPP--------------GVEPYPYPIPT---------VP 299
P++ F L P + +PP G +P +P VP
Sbjct: 2452 RPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVP 2511
Query: 300 EELPPGTEPEP---AFQDDAANAPLEFKMAAGS-SGAPWMPKPGDDYSYNQFSTYGDANA 355
PP P AF + F A G S P +P+PG + S +G
Sbjct: 2512 SGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPT 2571
Query: 356 AGAYYQDYY---SGGYYPAQDP 374
G Y +G ++P+ P
Sbjct: 2572 LGKPQSTNYTVATGNFHPSGSP 2593
Score = 36.2 bits (82), Expect = 0.070
Identities = 36/138 (26%), Positives = 50/138 (36%), Gaps = 18/138 (13%)
Query: 9 SDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLL 68
S E + +PEP + P+ G +G P P L+ P P +P L+
Sbjct: 983 SPPPEANCTDPEPVPPMILPPSPGSPVG--------PASPILMEPLPPQCSPLLQHSLV- 1033
Query: 69 PPPTGDPRLQPPPPLPFGLGGFPPPPG--VSPAEAAGVGEGLGLGLPSPRGPGLN----- 121
P P PP LP + P G V ++ A + E + P P L
Sbjct: 1034 -PQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATS 1092
Query: 122 -LPPPIGGAGPPLGLPKP 138
LP P+G P P P
Sbjct: 1093 PLPSPMGDLSCPAPSPAP 1110
Score = 36.2 bits (82), Expect = 0.070
Identities = 85/336 (25%), Positives = 106/336 (31%), Gaps = 73/336 (21%)
Query: 66 LLLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPG---LNL 122
L +PP G PP P G P P A G + +P P PG L L
Sbjct: 2104 LRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKL 2163
Query: 123 PP----------PIGGA-----------GPPLGLPKPKKRKEPVKIAAPELHKGDSDSEE 161
PP P G A PP P P P A P + S
Sbjct: 2164 PPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAP---AQPPMLGASSRPGA 2220
Query: 162 DEPTKKKTILQG------SSEGTGLSALLPQPKNLTV---------KETNRLLLPHAF-- 204
+P + T G S+ L P NL V K + LL P F
Sbjct: 2221 GQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGE 2280
Query: 205 SRKPSD--------GSPDTKPSRLASKTKTSSLAPVVGTTTTTPSPSAIKAAAKSAALQV 256
SRK + SP P L SS + G T P KA A QV
Sbjct: 2281 SRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKT--PDVFKAPLTPRASQV 2338
Query: 257 TKQ-----ITQEEDDSDEEVAPE-----NFFSLPEKAEPPGVEPY-PYPIPTVPEE---L 302
Q + +E + +AP + F +P P P P P PE L
Sbjct: 2339 EPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCAL 2398
Query: 303 PPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKP 338
PP + P F A+ + SS +P P+P
Sbjct: 2399 PPRSLPSDPFSRVPAS-----PQSQSSSQSPLTPRP 2429
Score = 35.0 bits (79), Expect = 0.16
Identities = 30/80 (37%), Positives = 34/80 (42%), Gaps = 8/80 (10%)
Query: 70 PPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPG-LNLPPPIGG 128
PP +P Q P GL G P G P G + LG G P P+GP L PP
Sbjct: 4241 PPYQEPGTQTSPLQ--GLLGCQPQLGGFPGPQTGPLQELGAG-PRPQGPPRLPAPPGALS 4297
Query: 129 AGPPLG----LPKPKKRKEP 144
GP LG P P +EP
Sbjct: 4298 TGPVLGPVHPTPPPSSPQEP 4317
Score = 35.0 bits (79), Expect = 0.16
Identities = 23/64 (35%), Positives = 28/64 (43%), Gaps = 5/64 (7%)
Query: 41 SLPAPKGPALLPPPPQMLAPAFPPPLLLPPPTGDPRLQPPPPLPFGLGGFP----PPPGV 96
S P P+ P+ PP P +PA PP L +P +PP P P L P P P
Sbjct: 4907 SAPPPEEPSP-PPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRA 4965
Query: 97 SPAE 100
P E
Sbjct: 4966 RPPE 4969
Score = 30.8 bits (68), Expect = 2.9
Identities = 19/55 (34%), Positives = 22/55 (40%), Gaps = 1/55 (1%)
Query: 285 PPGVEPYPYPIPTVPEELPPGTEPEPAF-QDDAANAPLEFKMAAGSSGAPWMPKP 338
PP EP P P P P P TEP + A P+ + SS PKP
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKP 4963
Score = 29.3 bits (64), Expect = 8.5
Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 5/58 (8%)
Query: 261 TQEEDDSDEEVAPENFFSLPEKAEPPGVEP---YPYPIPTVPEELPPGTEPEPAFQDD 315
T ++ D ++A E L KA+ PG E P+P+ PE+ PGT E D
Sbjct: 1819 TSQKGDDGPDIADEESRGLEGKADTPGPEDGGVKASPVPSDPEK--PGTPGEGMLSSD 1874
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 58.9 bits (141), Expect = 1e-08
Identities = 43/139 (30%), Positives = 58/139 (41%), Gaps = 15/139 (10%)
Query: 1 MSLVAYASSDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAP 60
+ LV + + DE + E+ ++ P+ S PK + P + AP
Sbjct: 615 LDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAP--ITSADCPKPMVVTPGAAAVAAP 672
Query: 61 A-FPPPLLLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPG 119
+ P L LPPP G P L PPPP P GFP PP + P P P P
Sbjct: 673 SVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPP----------PPPAHPA 722
Query: 120 LNLPPPIGGAGPPLGLPKP 138
+ +PPP A P G+P P
Sbjct: 723 VTVPPPPLPAPP--GVPPP 739
Score = 48.9 bits (115), Expect = 1e-05
Identities = 32/79 (40%), Positives = 36/79 (45%), Gaps = 9/79 (11%)
Query: 28 APTSGPALGGLFASLPAPKG--PALLPPPPQMLAPAFPPPLLLPPPTGDPR------LQP 79
A + P++ LP P G P PPPP P FP P LPPP P P
Sbjct: 667 AAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVP 726
Query: 80 PPPLPFGLGGFPPPPGVSP 98
PPPLP G PPPP + P
Sbjct: 727 PPPLP-APPGVPPPPILPP 744
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/63 (41%), Positives = 30/63 (47%), Gaps = 4/63 (6%)
Query: 48 PALLPPPPQMLAPAFPPPLLLPPPTGDPRLQPPPPLPFGLGGFPP-PPGVSPAEAAGVGE 106
P LPPPP PA P + PPP P PPPP+ L PP PPG+ P +
Sbjct: 706 PPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPI---LPPLPPFPPGLFPVMQVDMSH 762
Query: 107 GLG 109
LG
Sbjct: 763 VLG 765
Score = 40.4 bits (93), Expect = 0.004
Identities = 40/122 (32%), Positives = 47/122 (38%), Gaps = 31/122 (25%)
Query: 43 PAPKGPAL-LPPPPQMLAPAFPPPLLLPP-PTGDPRLQPPP---------------PLPF 85
P P PA+ +PPPP P PPP +LPP P P L P P+ F
Sbjct: 716 PPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSF 775
Query: 86 ------------GLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPG--LNLPPPIGGAGP 131
G G P PP ++ A AA + LP RGP N P G P
Sbjct: 776 QMQTQVLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWP 835
Query: 132 PL 133
PL
Sbjct: 836 PL 837
Score = 37.4 bits (85), Expect = 0.031
Identities = 74/316 (23%), Positives = 98/316 (31%), Gaps = 56/316 (17%)
Query: 19 PEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPPPTGDPRLQ 78
P P EE G G F PAP P L P P PP PP T L
Sbjct: 408 PPPPEEPTATAAFGARDSGEFRRAPAP--PPLPPAEPLAKEKPGTPPGPPPPDTNSMELG 465
Query: 79 PPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGGAGPPLGLPKP 138
P G+ P P SP G SP GP P + +
Sbjct: 466 GRPTF-----GWSPEPCDSP--------GTPTLESSPAGP----EKPHDSLDSRIEMLLK 508
Query: 139 KKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGLSALLPQPKNLTVKETNRL 198
++R + + + P DSD+E ++GS + S L P T +
Sbjct: 509 EQRTKLLFLREP-----DSDTELQ--------MEGSPISSSSSQLSPLAPFGTNSQPGFR 555
Query: 199 LLPHAFSRKPSDGSPDTKPSRLASKTKTS----SLAPVVGTTTTTPSPSAIKAAAKSAAL 254
SR S G D P+ L + L P P P+ + + AL
Sbjct: 556 GPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVAL 615
Query: 255 QVTKQIT---------QEEDDSDEEVAPENFFSLP--------EKAEPPGVEPYPYP--- 294
+ T Q+ D E++ + S P PG P
Sbjct: 616 DLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVL 675
Query: 295 IPTVPEELPPGTEPEP 310
PT+P PPG P P
Sbjct: 676 APTLPLPPPPGFPPLP 691
Score = 37.4 bits (85), Expect = 0.031
Identities = 83/356 (23%), Positives = 111/356 (31%), Gaps = 76/356 (21%)
Query: 8 SSDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLL 67
++D S P PEP E+ T G G L S PA P + + L
Sbjct: 1299 TTDASHPS-VPPEPLAEDHPPHTPG-LCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLS 1356
Query: 68 LPPPTGDPRLQPPPPLPFGLGGFPPPPG----VSPAEAAGVGEGLGLGLPSPRGPGLNLP 123
P G P P P GG P PG +P + G L P P G
Sbjct: 1357 SPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERS 1416
Query: 124 PPIGGAGPPL---GLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGL 180
P+ A P L GLP P P+ +A P + + + + T L
Sbjct: 1417 GPL--ASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAP-----------------TPL 1457
Query: 181 SALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTP 240
LLP P P RKP G P P S+ + G P
Sbjct: 1458 PPLLPAP---------LASCPPPMKRKP--GRPRRSP---------PSMLSLDGPLVRPP 1497
Query: 241 SPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVP- 299
+ +A+ + L Q D +F + A PP + P P P P P
Sbjct: 1498 AGAAL--GRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPP 1555
Query: 300 -----------------EELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKP 338
E +PPG P +D+ +E + G PW P
Sbjct: 1556 VEPTKLPFKELDNQWPSEAIPPG----PRGRDEVTEEYMELAKSRG----PWRRPP 1603
Score = 32.0 bits (71), Expect = 1.3
Identities = 50/186 (26%), Positives = 58/186 (31%), Gaps = 48/186 (25%)
Query: 23 EEEAVAPTSGPALGGLFASLPAPKG---PA------------------LLPPPPQMLAPA 61
E EAVAP P++ P P G PA L P PP A
Sbjct: 1194 ETEAVAPEERPSM---LDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEA 1250
Query: 62 FPPPLLLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLN 121
PP P D ++P PP+ L PP LP PR P
Sbjct: 1251 RPPLSPERAPEHDLEVEPEPPMMLPLPLQPP-------------------LPPPRPPRPP 1291
Query: 122 LPPP---IGGAGPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKK--KTILQGSSE 176
PPP A P P+P P S S E P + L G S
Sbjct: 1292 SPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSS 1351
Query: 177 GTGLSA 182
G LS+
Sbjct: 1352 GLSLSS 1357
Score = 30.8 bits (68), Expect = 2.9
Identities = 25/93 (26%), Positives = 34/93 (36%), Gaps = 12/93 (12%)
Query: 234 GTTTTTPSPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPY 293
G +P P A + A+ + + D EV PE LP +PP P P
Sbjct: 1235 GAMLLSPEPPAKEVEARPPLSP------ERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPP 1288
Query: 294 PIPTVPEE------LPPGTEPEPAFQDDAANAP 320
P+ P E P PEP +D + P
Sbjct: 1289 RPPSPPPEPETTDASHPSVPPEPLAEDHPPHTP 1321
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 58.2 bits (139), Expect = 2e-08
Identities = 78/324 (24%), Positives = 112/324 (34%), Gaps = 36/324 (11%)
Query: 18 EPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPPPTGDPRL 77
EP P + APT+ PAP P P+ AP P P PT P+
Sbjct: 261 EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK---PAPT-TPK- 315
Query: 78 QPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGGAGPPLGLPK 137
+P P P P +P E A P+ + P P P P
Sbjct: 316 EPAPTTP------KEPTPTTPKEPA----------PTTKEPAPTTPKEPAPTAPKK--PA 357
Query: 138 PKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGLSALLPQPKNLTVKETNR 197
P KEP E + ++E PT K +++ + P P T
Sbjct: 358 PTTPKEPAPTTPKE--PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP 415
Query: 198 LLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTPSPSAIKAAAKSAALQVT 257
+++P+ +P K ++ TT P+P+ K A + +
Sbjct: 416 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 475
Query: 258 KQITQEE-DDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPEELPPGTEPEPAFQDDA 316
+E + +++ P + PEK P E P PT PEEL P T EP
Sbjct: 476 PTTPKETAPTTPKKLTP----TTPEKLAPTTPEK---PAPTTPEELAPTTPEEPTPTTPE 528
Query: 317 ANAPLEFKMAAGSS---GAPWMPK 337
AP K AA ++ AP PK
Sbjct: 529 EPAPTTPKAAAPNTPKEPAPTTPK 552
Score = 55.8 bits (133), Expect = 8e-08
Identities = 79/302 (26%), Positives = 95/302 (31%), Gaps = 51/302 (16%)
Query: 18 EPEPEEEEAVAPTSGPALGGLFASLPAPKGPA-LLPPPPQMLAPAFPPPLLLPPPTGDPR 76
EP P + APT+ AP P L P P+ LAP P P PT
Sbjct: 457 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK---PAPTTPEE 513
Query: 77 LQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGGAGPPLGLP 136
L P P P +P E A +P+ N P P P
Sbjct: 514 LAPTTP--------EEPTPTTPEEPAPT---------TPKAAAPNTPKEPAPTTPKEPAP 556
Query: 137 KPKKRKEPV--KIAAPELHKGDSDSEEDEP---TKKKTILQGSSEGTGLSALLPQPKNL- 190
K P K AP KG + + EP T KK P PK L
Sbjct: 557 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK----------------PAPKELA 600
Query: 191 --TVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTT---PSPSAI 245
T KE P +P T + K + GT TT P+P+
Sbjct: 601 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 660
Query: 246 KAAA-KSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPEELPP 304
K A K A TK T D P+ + P + P P PT PE PP
Sbjct: 661 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKE--TAPTTPKEPAPTTPKKPAPTTPETPPP 718
Query: 305 GT 306
T
Sbjct: 719 TT 720
Score = 51.6 bits (122), Expect = 2e-06
Identities = 72/325 (22%), Positives = 103/325 (31%), Gaps = 51/325 (15%)
Query: 17 AEPEPEEEEAVAPTSGPALGGLFASLPAPKGPA-LLPPPPQMLAPAFPPPLLLPPPTGDP 75
A+P P+ E T GPAL PK P P P P P P + P
Sbjct: 195 AKPTPKAETT---TKGPAL-------TTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP 244
Query: 76 RLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGGAGPPLGL 135
+ +P P P P + + P+P P P P
Sbjct: 245 K-EPAPTTTKSAPTTPKEPAPTTTKE-----------PAPTTPKEPAPTTTKEPAPTTTK 292
Query: 136 PKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGLSALLPQPKNLTVKET 195
P KEP AP K + + EP +P T KE
Sbjct: 293 SAPTTPKEP----APTTPKKPAPTTPKEPAPTTP---------------KEPTPTTPKE- 332
Query: 196 NRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTPSPSAIKAAAKSAALQ 255
P +++P+ +P K ++ TT P+P+ K + + +
Sbjct: 333 -----PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 387
Query: 256 VTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPEELPPGTEPEPA---F 312
T+ + +E AP S P + P P PT P+E P T +PA
Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 447
Query: 313 QDDAANAPLEFKMAAGSSGAPWMPK 337
++ A P E AP PK
Sbjct: 448 KEPAPTTPKEPAPTTTKKPAPTTPK 472
Score = 50.8 bits (120), Expect = 3e-06
Identities = 70/298 (23%), Positives = 99/298 (33%), Gaps = 43/298 (14%)
Query: 14 PDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPPPTG 73
P E P +E A T PA PK PA P P+ AP P L PT
Sbjct: 447 PKEPAPTTPKEPAPTTTKKPAP-------TTPKEPA--PTTPKETAPTTPKKLT---PTT 494
Query: 74 DPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGGAGPPL 133
+L P P P +P E A +P P P P
Sbjct: 495 PEKLAPTTP--------EKPAPTTPEELAPT---------TPEEPTPTTPEEPAPTTPKA 537
Query: 134 GLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGLSALLPQPKNLTVK 193
P K P P + +E PT K + +GT + L +P T K
Sbjct: 538 AAPNTPKEPAPTTPKEP----APTTPKEPAPTTPKETAPTTPKGTAPTTL-KEPAPTTPK 592
Query: 194 ETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTPSPSAIKAAAKSAA 253
+ L +++P+ + D T ++ TT P+P+ K A +
Sbjct: 593 KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTL 652
Query: 254 LQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPEELPPGTEPEPA 311
+ T + + +E+AP + P P PT P+E P T EPA
Sbjct: 653 KEPAP--TTPKKPAPKELAPTT-------TKGPTSTTSDKPAPTTPKETAPTTPKEPA 701
Score = 43.5 bits (101), Expect = 4e-04
Identities = 75/324 (23%), Positives = 101/324 (31%), Gaps = 38/324 (11%)
Query: 18 EPEPEEEEAVAPTSGPALGGLFASLPAP----------KGPALLPPPPQMLAPAFPPPLL 67
EP P + APT+ PAP K PA P P P
Sbjct: 363 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 422
Query: 68 LPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPG---LNLPP 124
P +P P P P +P E A +P+ P P
Sbjct: 423 TKEPAPTTPKEPAPTTP------KKPAPTTPKEPAPT---------TPKEPAPTTTKKPA 467
Query: 125 PIGGAGPPLGLPKPKKRKEPVKIAAPELHK-GDSDSEEDEPTKKKTILQGS-SEGTGLSA 182
P P PK P K+ K + E+ PT + + + E T +
Sbjct: 468 PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 527
Query: 183 LLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTT--- 239
P P N P + P + +P T + K ++ GT TT
Sbjct: 528 EEPAPTTPKAAAPNTPKEPAPTT--PKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 585
Query: 240 PSPSAIKAAA-KSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTV 298
P+P+ K A K A TK+ T D P+ + P + P P PT
Sbjct: 586 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG--TAPTTPKEPAPTTPKEPAPTT 643
Query: 299 PEELPPGTEPEPAFQDDAANAPLE 322
P+ P T EPA AP E
Sbjct: 644 PKGTAPTTLKEPAPTTPKKPAPKE 667
Score = 41.6 bits (96), Expect = 0.002
Identities = 63/262 (24%), Positives = 89/262 (33%), Gaps = 24/262 (9%)
Query: 13 EPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGP-ALLPPPPQMLAPAFP--PPLLLP 69
EP P+ + +APT+ PAP P P P+ AP P P P
Sbjct: 585 EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 644
Query: 70 PPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGGA 129
T L+ P P P P ++P G P+P P P
Sbjct: 645 KGTAPTTLKEPAPTT---PKKPAPKELAPTTTKGPTSTTS-DKPAPTTPKETAPTT---- 696
Query: 130 GPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKK---TILQGSSEGTGLSALLPQ 186
P P K+ P P + SE PT K TI + E T + P
Sbjct: 697 -PKEPAPTTPKKPAPTTPETPP----PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPT 751
Query: 187 PKNL--TVKETNRLLLPHAFSRKP---SDGSPDTKPSRLASKTKTSSLAPVVGTTTTTPS 241
PK L + KE + KP + T L + +T++ AP + T T +
Sbjct: 752 PKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTT 811
Query: 242 PSAIKAAAKSAALQVTKQITQE 263
++ + QVT TQ+
Sbjct: 812 EKTTESKITATTTQVTSTTTQD 833
Score = 40.8 bits (94), Expect = 0.003
Identities = 76/355 (21%), Positives = 101/355 (28%), Gaps = 48/355 (13%)
Query: 11 ESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPP----PQMLAPAFPPPL 66
E P EP P + APT+ PAP P P P P P P
Sbjct: 332 EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT 391
Query: 67 LL---------PPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRG 117
P PT P P P P +P E A +P+
Sbjct: 392 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP-TTPKEPAPT---------TPKK 441
Query: 118 PGLNLPPPIGGAGPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEG 177
P P P P K+ P P + +E PT K + + E
Sbjct: 442 PAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP----APTTPKETAPTTPKKLTPTTPEK 497
Query: 178 TG--------------LSALLPQPKNLTVKETNRLLLPHAFS-RKPSDGSPDTKPSRLAS 222
L+ P+ T E P A + P + +P T +
Sbjct: 498 LAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPT 557
Query: 223 KTKTSSLAPVVGTTTTTPSPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEK 282
K + T TTP +A + A K +E + + P
Sbjct: 558 TPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 617
Query: 283 AEPPGVEPYPYPIPTVPEELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPK 337
P G P T P+E P T EPA AP K A ++ PK
Sbjct: 618 TTPKGTAP------TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPK 666
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.131 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,567,582
Number of Sequences: 37866
Number of extensions: 2269500
Number of successful extensions: 27583
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 452
Number of HSP's successfully gapped in prelim test: 1468
Number of HSP's that attempted gapping in prelim test: 11650
Number of HSP's gapped (non-prelim): 8828
length of query: 491
length of database: 18,247,518
effective HSP length: 106
effective length of query: 385
effective length of database: 14,233,722
effective search space: 5479982970
effective search space used: 5479982970
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.