Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 40806181
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40806181 receptor interacting protein kinase 5 isoform 2
[Homo sapiens]
(884 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40806181 receptor interacting protein kinase 5 isoform 2 [Hom... 1785 0.0
gi|40806179 receptor interacting protein kinase 5 isoform 1 [Hom... 1763 0.0
gi|85838511 mitogen-activated protein kinase kinase kinase 2 [Ho... 74 5e-13
gi|42794767 mitogen-activated protein kinase kinase kinase 3 iso... 70 7e-12
gi|42794765 mitogen-activated protein kinase kinase kinase 3 iso... 70 7e-12
gi|62422554 p21-activated kinase 4 isoform 1 [Homo sapiens] 70 7e-12
gi|62422561 p21-activated kinase 4 isoform 2 [Homo sapiens] 70 7e-12
gi|62422563 p21-activated kinase 4 isoform 2 [Homo sapiens] 70 7e-12
gi|62422557 p21-activated kinase 4 isoform 1 [Homo sapiens] 70 7e-12
gi|5031975 p21-activated kinase 4 isoform 1 [Homo sapiens] 70 7e-12
gi|18250298 src-related kinase lacking C-terminal regulatory tyr... 70 1e-11
gi|5453976 protein kinase C, theta [Homo sapiens] 69 2e-11
gi|29826329 p21-activated kinase 7 [Homo sapiens] 68 3e-11
gi|24308191 p21-activated kinase 7 [Homo sapiens] 68 3e-11
gi|148746218 TAO kinase 3 [Homo sapiens] 67 6e-11
gi|223671888 interleukin-1 receptor-associated kinase 4 isoform ... 67 7e-11
gi|223671885 interleukin-1 receptor-associated kinase 4 isoform ... 67 7e-11
gi|223671883 interleukin-1 receptor-associated kinase 4 isoform ... 67 7e-11
gi|166795293 interleukin-1 receptor-associated kinase 4 isoform ... 67 7e-11
gi|166795295 interleukin-1 receptor-associated kinase 4 isoform ... 67 7e-11
gi|47157325 protein kinase C, delta [Homo sapiens] 65 3e-10
gi|31377782 protein kinase C, delta [Homo sapiens] 65 3e-10
gi|134288915 myosin IIIB isoform 1 [Homo sapiens] 64 8e-10
gi|134288892 myosin IIIB isoform 2 [Homo sapiens] 64 8e-10
gi|4506067 protein kinase C, alpha [Homo sapiens] 63 1e-09
gi|47132591 protein kinase N1 isoform 1 [Homo sapiens] 63 1e-09
gi|47132589 protein kinase N1 isoform 2 [Homo sapiens] 63 1e-09
gi|133908623 protein kinase C, iota [Homo sapiens] 62 2e-09
gi|45439370 TAO kinase 1 [Homo sapiens] 62 2e-09
gi|191252782 p21-activated kinase 6 [Homo sapiens] 62 2e-09
>gi|40806181 receptor interacting protein kinase 5 isoform 2 [Homo
sapiens]
Length = 884
Score = 1785 bits (4623), Expect = 0.0
Identities = 884/884 (100%), Positives = 884/884 (100%)
Query: 1 MEGDGVPWGSEPVSGPGPGGGGMIRELCRGFGRYRRYLGRLRQNLRETQKFFRDIKCSHN 60
MEGDGVPWGSEPVSGPGPGGGGMIRELCRGFGRYRRYLGRLRQNLRETQKFFRDIKCSHN
Sbjct: 1 MEGDGVPWGSEPVSGPGPGGGGMIRELCRGFGRYRRYLGRLRQNLRETQKFFRDIKCSHN 60
Query: 61 HTCLSSLTGGGGAERGPAGDVAETGLQAGQLSCISFPPKEEKYLQQIVDCLPCILILGQD 120
HTCLSSLTGGGGAERGPAGDVAETGLQAGQLSCISFPPKEEKYLQQIVDCLPCILILGQD
Sbjct: 61 HTCLSSLTGGGGAERGPAGDVAETGLQAGQLSCISFPPKEEKYLQQIVDCLPCILILGQD 120
Query: 121 CNVKCQLLNLLLGVQVLPTTKLGSEESCKLRRLRFTYGTQTRVSLALPGQYELVHTLVAH 180
CNVKCQLLNLLLGVQVLPTTKLGSEESCKLRRLRFTYGTQTRVSLALPGQYELVHTLVAH
Sbjct: 121 CNVKCQLLNLLLGVQVLPTTKLGSEESCKLRRLRFTYGTQTRVSLALPGQYELVHTLVAH 180
Query: 181 QGNWETIPEEDLEVQENNEDAAHVLAELEVTMHHALLQEVDVVVAPCQGLRPTVDVLGDL 240
QGNWETIPEEDLEVQENNEDAAHVLAELEVTMHHALLQEVDVVVAPCQGLRPTVDVLGDL
Sbjct: 181 QGNWETIPEEDLEVQENNEDAAHVLAELEVTMHHALLQEVDVVVAPCQGLRPTVDVLGDL 240
Query: 241 VNDFLPVITYALHKDELSERDEQELQEIRKYFSFPVFFFKVPKLGSEIIDSSTRRMESER 300
VNDFLPVITYALHKDELSERDEQELQEIRKYFSFPVFFFKVPKLGSEIIDSSTRRMESER
Sbjct: 241 VNDFLPVITYALHKDELSERDEQELQEIRKYFSFPVFFFKVPKLGSEIIDSSTRRMESER 300
Query: 301 SPLYRQLIDLGYLSSSHWNCGAPGQDTKAQSMLVEQSEKLRHLSTFSHQVLQTRLVDAAK 360
SPLYRQLIDLGYLSSSHWNCGAPGQDTKAQSMLVEQSEKLRHLSTFSHQVLQTRLVDAAK
Sbjct: 301 SPLYRQLIDLGYLSSSHWNCGAPGQDTKAQSMLVEQSEKLRHLSTFSHQVLQTRLVDAAK 360
Query: 361 ALNLVHCHCLDIFINQAFDMQRDLQITPKRLEYTRKKENELYESLMNIANRKQEEMKDMI 420
ALNLVHCHCLDIFINQAFDMQRDLQITPKRLEYTRKKENELYESLMNIANRKQEEMKDMI
Sbjct: 361 ALNLVHCHCLDIFINQAFDMQRDLQITPKRLEYTRKKENELYESLMNIANRKQEEMKDMI 420
Query: 421 VETLNTMKEELLDDATNMEFKDVIVPENGEPVGTREIKCCIRQIQELIISRLNQAVANKL 480
VETLNTMKEELLDDATNMEFKDVIVPENGEPVGTREIKCCIRQIQELIISRLNQAVANKL
Sbjct: 421 VETLNTMKEELLDDATNMEFKDVIVPENGEPVGTREIKCCIRQIQELIISRLNQAVANKL 480
Query: 481 ISSVDYLRESFVGTLERCLQSLEKSQDVSVHITSNYLKQILNAAYHVEVTFHSGSSVTRM 540
ISSVDYLRESFVGTLERCLQSLEKSQDVSVHITSNYLKQILNAAYHVEVTFHSGSSVTRM
Sbjct: 481 ISSVDYLRESFVGTLERCLQSLEKSQDVSVHITSNYLKQILNAAYHVEVTFHSGSSVTRM 540
Query: 541 LWEQIKQIIQRITWVSPPAITLEWKRKVAQEAIESLSASKLAKSICSQFRTRLNSSHEAF 600
LWEQIKQIIQRITWVSPPAITLEWKRKVAQEAIESLSASKLAKSICSQFRTRLNSSHEAF
Sbjct: 541 LWEQIKQIIQRITWVSPPAITLEWKRKVAQEAIESLSASKLAKSICSQFRTRLNSSHEAF 600
Query: 601 AASLRQLEAGHSGRLEKTEDLWLRVRKDHAPRLARLSLESCSLQDVLLHRKPKLGQELGR 660
AASLRQLEAGHSGRLEKTEDLWLRVRKDHAPRLARLSLESCSLQDVLLHRKPKLGQELGR
Sbjct: 601 AASLRQLEAGHSGRLEKTEDLWLRVRKDHAPRLARLSLESCSLQDVLLHRKPKLGQELGR 660
Query: 661 GQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDY 720
GQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDY
Sbjct: 661 GQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDY 720
Query: 721 NYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIALDVVEGIRFLHSQGLVHRDIKL 780
NYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIALDVVEGIRFLHSQGLVHRDIKL
Sbjct: 721 NYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIALDVVEGIRFLHSQGLVHRDIKL 780
Query: 781 KNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGARPERLPVFDEECWQLM 840
KNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGARPERLPVFDEECWQLM
Sbjct: 781 KNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGARPERLPVFDEECWQLM 840
Query: 841 EACWDGDPLKRPLLGIVQPMLQGIMNRLCKSNSEQPNRGLDDST 884
EACWDGDPLKRPLLGIVQPMLQGIMNRLCKSNSEQPNRGLDDST
Sbjct: 841 EACWDGDPLKRPLLGIVQPMLQGIMNRLCKSNSEQPNRGLDDST 884
>gi|40806179 receptor interacting protein kinase 5 isoform 1 [Homo
sapiens]
Length = 929
Score = 1763 bits (4567), Expect = 0.0
Identities = 884/929 (95%), Positives = 884/929 (95%), Gaps = 45/929 (4%)
Query: 1 MEGDGVPWGSEPVSGPGPGGGGMIRELCRGFGRYRRYLGRLRQNLRETQKFFRDIKCSHN 60
MEGDGVPWGSEPVSGPGPGGGGMIRELCRGFGRYRRYLGRLRQNLRETQKFFRDIKCSHN
Sbjct: 1 MEGDGVPWGSEPVSGPGPGGGGMIRELCRGFGRYRRYLGRLRQNLRETQKFFRDIKCSHN 60
Query: 61 HTCLSSLTGGGGAERGPAGDVAETGLQAGQLSCISFPPKEEKYLQQIVDCLPCILILGQD 120
HTCLSSLTGGGGAERGPAGDVAETGLQAGQLSCISFPPKEEKYLQQIVDCLPCILILGQD
Sbjct: 61 HTCLSSLTGGGGAERGPAGDVAETGLQAGQLSCISFPPKEEKYLQQIVDCLPCILILGQD 120
Query: 121 CNVKCQLLNLLLGVQVLPTTKLGSEESCKLRRLRFTYGTQTRVSLALPGQYELVHTLVAH 180
CNVKCQLLNLLLGVQVLPTTKLGSEESCKLRRLRFTYGTQTRVSLALPGQYELVHTLVAH
Sbjct: 121 CNVKCQLLNLLLGVQVLPTTKLGSEESCKLRRLRFTYGTQTRVSLALPGQYELVHTLVAH 180
Query: 181 QGNWETIPEEDLEVQENNEDAAHVLAELEVTMHHALLQEVDVVVAPCQGLRPTVDVLGDL 240
QGNWETIPEEDLEVQENNEDAAHVLAELEVTMHHALLQEVDVVVAPCQGLRPTVDVLGDL
Sbjct: 181 QGNWETIPEEDLEVQENNEDAAHVLAELEVTMHHALLQEVDVVVAPCQGLRPTVDVLGDL 240
Query: 241 VNDFLPVITYALHKDELSERDEQELQEIRKYFSFPVFFFKVPKLGSEIIDSSTRRMESER 300
VNDFLPVITYALHKDELSERDEQELQEIRKYFSFPVFFFKVPKLGSEIIDSSTRRMESER
Sbjct: 241 VNDFLPVITYALHKDELSERDEQELQEIRKYFSFPVFFFKVPKLGSEIIDSSTRRMESER 300
Query: 301 SPLYRQLIDLGYLSSSHWNCGAPGQDTKAQSMLVEQSEKLRHLSTFSHQVLQTRLVDAAK 360
SPLYRQLIDLGYLSSSHWNCGAPGQDTKAQSMLVEQSEKLRHLSTFSHQVLQTRLVDAAK
Sbjct: 301 SPLYRQLIDLGYLSSSHWNCGAPGQDTKAQSMLVEQSEKLRHLSTFSHQVLQTRLVDAAK 360
Query: 361 ALNLVHCHCLDIFINQAFDMQRDLQITPKRLEYTRKKENELYESLMNIANRKQEEMKDMI 420
ALNLVHCHCLDIFINQAFDMQRDLQITPKRLEYTRKKENELYESLMNIANRKQEEMKDMI
Sbjct: 361 ALNLVHCHCLDIFINQAFDMQRDLQITPKRLEYTRKKENELYESLMNIANRKQEEMKDMI 420
Query: 421 VETLNTMKEELLDDATNMEFKDVIVPENGEPVGTREIKCCIRQIQELIISRLNQAVANKL 480
VETLNTMKEELLDDATNMEFKDVIVPENGEPVGTREIKCCIRQIQELIISRLNQAVANKL
Sbjct: 421 VETLNTMKEELLDDATNMEFKDVIVPENGEPVGTREIKCCIRQIQELIISRLNQAVANKL 480
Query: 481 ISSVDYLRESFVGTLERCLQSLEKSQDVSVHITSNYLKQILNAAYHVEVTFHSGSSVTRM 540
ISSVDYLRESFVGTLERCLQSLEKSQDVSVHITSNYLKQILNAAYHVEVTFHSGSSVTRM
Sbjct: 481 ISSVDYLRESFVGTLERCLQSLEKSQDVSVHITSNYLKQILNAAYHVEVTFHSGSSVTRM 540
Query: 541 LWEQIKQIIQRITWVSPPAITLEWKRKVAQEAIESLSASKLAKSICSQFRTRLNSSHEAF 600
LWEQIKQIIQRITWVSPPAITLEWKRKVAQEAIESLSASKLAKSICSQFRTRLNSSHEAF
Sbjct: 541 LWEQIKQIIQRITWVSPPAITLEWKRKVAQEAIESLSASKLAKSICSQFRTRLNSSHEAF 600
Query: 601 AASLRQLEAGHSGRLEKTEDLWLRVRKDHAPRLARLSLESCSLQDVLLHRKPKLGQELGR 660
AASLRQLEAGHSGRLEKTEDLWLRVRKDHAPRLARLSLESCSLQDVLLHRKPKLGQELGR
Sbjct: 601 AASLRQLEAGHSGRLEKTEDLWLRVRKDHAPRLARLSLESCSLQDVLLHRKPKLGQELGR 660
Query: 661 GQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDY 720
GQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDY
Sbjct: 661 GQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGSVIDY 720
Query: 721 NYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIALDVVEGIRFLHSQGLVHRDIKL 780
NYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIALDVVEGIRFLHSQGLVHRDIKL
Sbjct: 721 NYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIALDVVEGIRFLHSQGLVHRDIKL 780
Query: 781 KNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFT------------------ 822
KNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFT
Sbjct: 781 KNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGKYDNSVDVYAFGILFWY 840
Query: 823 ---------------------------GARPERLPVFDEECWQLMEACWDGDPLKRPLLG 855
GARPERLPVFDEECWQLMEACWDGDPLKRPLLG
Sbjct: 841 ICSGSVKLPEAFERCASKDHLWNNVRRGARPERLPVFDEECWQLMEACWDGDPLKRPLLG 900
Query: 856 IVQPMLQGIMNRLCKSNSEQPNRGLDDST 884
IVQPMLQGIMNRLCKSNSEQPNRGLDDST
Sbjct: 901 IVQPMLQGIMNRLCKSNSEQPNRGLDDST 929
>gi|85838511 mitogen-activated protein kinase kinase kinase 2 [Homo
sapiens]
Length = 619
Score = 74.3 bits (181), Expect = 5e-13
Identities = 60/185 (32%), Positives = 89/185 (48%), Gaps = 20/185 (10%)
Query: 653 KLGQELGRGQYGVVYLCDNWGGHFPCALKSVV-----PPDEKHWNDLALEFHYMRSLPKH 707
+LG+ LG+G +G VYLC + A+K V P K N L E +++L H
Sbjct: 357 RLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNL-LH 415
Query: 708 ERLVDLHGSVIDYNYGGGSSIAVLLIMERLHR-DLYTGLKA--GLTLETRLQIALDVVEG 764
ER+V +G + D + + ME + + LKA LT + ++EG
Sbjct: 416 ERIVQYYGCLRD-----PQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEG 470
Query: 765 IRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCK--PEAMMSG----SIVGTPIHMAP 818
+ +LHS +VHRDIK N+L D K+ D G K +SG S+ GTP M+P
Sbjct: 471 VHYLHSNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSP 530
Query: 819 ELFTG 823
E+ +G
Sbjct: 531 EVISG 535
>gi|42794767 mitogen-activated protein kinase kinase kinase 3
isoform 1 [Homo sapiens]
Length = 657
Score = 70.5 bits (171), Expect = 7e-12
Identities = 59/183 (32%), Positives = 88/183 (48%), Gaps = 20/183 (10%)
Query: 655 GQELGRGQYGVVYLCDNWGGHFPCALKSVV-----PPDEKHWNDLALEFHYMRSLPKHER 709
G+ LG+G +G VYLC + A K V P K + L E +++L +HER
Sbjct: 396 GKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNL-QHER 454
Query: 710 LVDLHGSVIDYNYGGGSSIAVLLIMERLHR-DLYTGLKA--GLTLETRLQIALDVVEGIR 766
+V +G + D + + + ME + + LKA LT + ++EG+
Sbjct: 455 IVQYYGCLRDR-----AEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMS 509
Query: 767 FLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCK--PEAMMSG----SIVGTPIHMAPEL 820
+LHS +VHRDIK N+L D K+ D G K MSG S+ GTP M+PE+
Sbjct: 510 YLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEV 569
Query: 821 FTG 823
+G
Sbjct: 570 ISG 572
>gi|42794765 mitogen-activated protein kinase kinase kinase 3
isoform 2 [Homo sapiens]
Length = 626
Score = 70.5 bits (171), Expect = 7e-12
Identities = 59/183 (32%), Positives = 88/183 (48%), Gaps = 20/183 (10%)
Query: 655 GQELGRGQYGVVYLCDNWGGHFPCALKSVV-----PPDEKHWNDLALEFHYMRSLPKHER 709
G+ LG+G +G VYLC + A K V P K + L E +++L +HER
Sbjct: 365 GKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALECEIQLLKNL-QHER 423
Query: 710 LVDLHGSVIDYNYGGGSSIAVLLIMERLHR-DLYTGLKA--GLTLETRLQIALDVVEGIR 766
+V +G + D + + + ME + + LKA LT + ++EG+
Sbjct: 424 IVQYYGCLRDR-----AEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMS 478
Query: 767 FLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCK--PEAMMSG----SIVGTPIHMAPEL 820
+LHS +VHRDIK N+L D K+ D G K MSG S+ GTP M+PE+
Sbjct: 479 YLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTPYWMSPEV 538
Query: 821 FTG 823
+G
Sbjct: 539 ISG 541
>gi|62422554 p21-activated kinase 4 isoform 1 [Homo sapiens]
Length = 591
Score = 70.5 bits (171), Expect = 7e-12
Identities = 67/235 (28%), Positives = 104/235 (44%), Gaps = 31/235 (13%)
Query: 657 ELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGS 716
++G G G+V + A+K + ++ L E MR +HE +V+++ S
Sbjct: 326 KIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDY-QHENVVEMYNS 384
Query: 717 VIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLTL--ETRLQIALDVVEGIRFLHSQGLV 774
Y G + V +ME L T + + E + L V++ + LH+QG++
Sbjct: 385 -----YLVGDELWV--VMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVI 437
Query: 775 HRDIKLKNVLLDKQNRAKITDLGFC---KPEAMMSGSIVGTPIHMAPELFTGA--RPE-- 827
HRDIK ++LL R K++D GFC E S+VGTP MAPEL + PE
Sbjct: 438 HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVD 497
Query: 828 --------------RLPVFDEECWQLMEACWDGDPLKRPLLGIVQPMLQGIMNRL 868
P F+E + M+ D P + L V P L+G ++RL
Sbjct: 498 IWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRL 552
>gi|62422561 p21-activated kinase 4 isoform 2 [Homo sapiens]
Length = 438
Score = 70.5 bits (171), Expect = 7e-12
Identities = 67/235 (28%), Positives = 104/235 (44%), Gaps = 31/235 (13%)
Query: 657 ELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGS 716
++G G G+V + A+K + ++ L E MR +HE +V+++ S
Sbjct: 173 KIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDY-QHENVVEMYNS 231
Query: 717 VIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLTL--ETRLQIALDVVEGIRFLHSQGLV 774
Y G + V +ME L T + + E + L V++ + LH+QG++
Sbjct: 232 -----YLVGDELWV--VMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVI 284
Query: 775 HRDIKLKNVLLDKQNRAKITDLGFC---KPEAMMSGSIVGTPIHMAPELFTGA--RPE-- 827
HRDIK ++LL R K++D GFC E S+VGTP MAPEL + PE
Sbjct: 285 HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVD 344
Query: 828 --------------RLPVFDEECWQLMEACWDGDPLKRPLLGIVQPMLQGIMNRL 868
P F+E + M+ D P + L V P L+G ++RL
Sbjct: 345 IWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRL 399
>gi|62422563 p21-activated kinase 4 isoform 2 [Homo sapiens]
Length = 438
Score = 70.5 bits (171), Expect = 7e-12
Identities = 67/235 (28%), Positives = 104/235 (44%), Gaps = 31/235 (13%)
Query: 657 ELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGS 716
++G G G+V + A+K + ++ L E MR +HE +V+++ S
Sbjct: 173 KIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDY-QHENVVEMYNS 231
Query: 717 VIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLTL--ETRLQIALDVVEGIRFLHSQGLV 774
Y G + V +ME L T + + E + L V++ + LH+QG++
Sbjct: 232 -----YLVGDELWV--VMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVI 284
Query: 775 HRDIKLKNVLLDKQNRAKITDLGFC---KPEAMMSGSIVGTPIHMAPELFTGA--RPE-- 827
HRDIK ++LL R K++D GFC E S+VGTP MAPEL + PE
Sbjct: 285 HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVD 344
Query: 828 --------------RLPVFDEECWQLMEACWDGDPLKRPLLGIVQPMLQGIMNRL 868
P F+E + M+ D P + L V P L+G ++RL
Sbjct: 345 IWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRL 399
>gi|62422557 p21-activated kinase 4 isoform 1 [Homo sapiens]
Length = 591
Score = 70.5 bits (171), Expect = 7e-12
Identities = 67/235 (28%), Positives = 104/235 (44%), Gaps = 31/235 (13%)
Query: 657 ELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGS 716
++G G G+V + A+K + ++ L E MR +HE +V+++ S
Sbjct: 326 KIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDY-QHENVVEMYNS 384
Query: 717 VIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLTL--ETRLQIALDVVEGIRFLHSQGLV 774
Y G + V +ME L T + + E + L V++ + LH+QG++
Sbjct: 385 -----YLVGDELWV--VMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVI 437
Query: 775 HRDIKLKNVLLDKQNRAKITDLGFC---KPEAMMSGSIVGTPIHMAPELFTGA--RPE-- 827
HRDIK ++LL R K++D GFC E S+VGTP MAPEL + PE
Sbjct: 438 HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVD 497
Query: 828 --------------RLPVFDEECWQLMEACWDGDPLKRPLLGIVQPMLQGIMNRL 868
P F+E + M+ D P + L V P L+G ++RL
Sbjct: 498 IWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRL 552
>gi|5031975 p21-activated kinase 4 isoform 1 [Homo sapiens]
Length = 591
Score = 70.5 bits (171), Expect = 7e-12
Identities = 67/235 (28%), Positives = 104/235 (44%), Gaps = 31/235 (13%)
Query: 657 ELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGS 716
++G G G+V + A+K + ++ L E MR +HE +V+++ S
Sbjct: 326 KIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDY-QHENVVEMYNS 384
Query: 717 VIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLTL--ETRLQIALDVVEGIRFLHSQGLV 774
Y G + V +ME L T + + E + L V++ + LH+QG++
Sbjct: 385 -----YLVGDELWV--VMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVI 437
Query: 775 HRDIKLKNVLLDKQNRAKITDLGFC---KPEAMMSGSIVGTPIHMAPELFTGA--RPE-- 827
HRDIK ++LL R K++D GFC E S+VGTP MAPEL + PE
Sbjct: 438 HRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVD 497
Query: 828 --------------RLPVFDEECWQLMEACWDGDPLKRPLLGIVQPMLQGIMNRL 868
P F+E + M+ D P + L V P L+G ++RL
Sbjct: 498 IWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRL 552
>gi|18250298 src-related kinase lacking C-terminal regulatory
tyrosine and N-terminal myristylation sites [Homo
sapiens]
Length = 488
Score = 69.7 bits (169), Expect = 1e-11
Identities = 51/154 (33%), Positives = 75/154 (48%), Gaps = 9/154 (5%)
Query: 649 HRKPKLGQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHE 708
H + LG++LG G +G V+ W G P A+K + + K DLA E ++ L +HE
Sbjct: 227 HSEFALGRKLGEGYFGEVWE-GLWLGSLPVAIKVIKSANMK-LTDLAKEIQTLKGL-RHE 283
Query: 709 RLVDLHGSVIDYNYGGGSSIAVLLIMERLHRDLYTGLKAG--LTLETRLQIALDVVEGIR 766
RL+ LH GG V +M + + + G G L L L A V EG+
Sbjct: 284 RLIRLHAVCS----GGEPVYIVTELMRKGNLQAFLGTPEGRALRLPPLLGFACQVAEGMS 339
Query: 767 FLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCK 800
+L Q +VHRD+ +NVL+D K+ D G +
Sbjct: 340 YLEEQRVVHRDLAARNVLVDDGLACKVADFGLAR 373
>gi|5453976 protein kinase C, theta [Homo sapiens]
Length = 706
Score = 68.9 bits (167), Expect = 2e-11
Identities = 55/198 (27%), Positives = 92/198 (46%), Gaps = 34/198 (17%)
Query: 643 LQDVLLHRKPKLGQELGRGQYGVVYLCD----NWGGHFPCALKSVVPPD--------EKH 690
++D +LH+ LG+G +G V+L + N K VV D EK
Sbjct: 377 IEDFILHKM------LGKGSFGKVFLAEFKKTNQFFAIKALKKDVVLMDDDVECTMVEKR 430
Query: 691 WNDLALEFHYMRSLPKHERLVDLHGSVIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLT 750
LA E ++ + + + V++Y GG ++ ++ H+
Sbjct: 431 VLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGD----LMYHIQSCHK---------FD 477
Query: 751 LETRLQIALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAM---MSG 807
L A +++ G++FLHS+G+V+RD+KL N+LLDK KI D G CK + +
Sbjct: 478 LSRATFYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTN 537
Query: 808 SIVGTPIHMAPELFTGAR 825
+ GTP ++APE+ G +
Sbjct: 538 TFCGTPDYIAPEILLGQK 555
>gi|29826329 p21-activated kinase 7 [Homo sapiens]
Length = 719
Score = 68.2 bits (165), Expect = 3e-11
Identities = 57/189 (30%), Positives = 88/189 (46%), Gaps = 19/189 (10%)
Query: 657 ELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGS 716
++G G G+V + A+K + ++ L E MR H+ +VD++ S
Sbjct: 454 KIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDY-HHDNVVDMYSS 512
Query: 717 VIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLTL--ETRLQIALDVVEGIRFLHSQGLV 774
Y G + V +ME L T + + E + L V+ + +LH+QG++
Sbjct: 513 -----YLVGDELWV--VMEFLEGGALTDIVTHTRMNEEQIATVCLSVLRALSYLHNQGVI 565
Query: 775 HRDIKLKNVLLDKQNRAKITDLGFC---KPEAMMSGSIVGTPIHMAPELFTGARPERLPV 831
HRDIK ++LL R K++D GFC E S+VGTP MAPE+ + RLP
Sbjct: 566 HRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVIS-----RLPY 620
Query: 832 FDE-ECWQL 839
E + W L
Sbjct: 621 GTEVDIWSL 629
>gi|24308191 p21-activated kinase 7 [Homo sapiens]
Length = 719
Score = 68.2 bits (165), Expect = 3e-11
Identities = 57/189 (30%), Positives = 88/189 (46%), Gaps = 19/189 (10%)
Query: 657 ELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGS 716
++G G G+V + A+K + ++ L E MR H+ +VD++ S
Sbjct: 454 KIGEGSTGIVCIATEKHTGKQVAVKKMDLRKQQRRELLFNEVVIMRDY-HHDNVVDMYSS 512
Query: 717 VIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLTL--ETRLQIALDVVEGIRFLHSQGLV 774
Y G + V +ME L T + + E + L V+ + +LH+QG++
Sbjct: 513 -----YLVGDELWV--VMEFLEGGALTDIVTHTRMNEEQIATVCLSVLRALSYLHNQGVI 565
Query: 775 HRDIKLKNVLLDKQNRAKITDLGFC---KPEAMMSGSIVGTPIHMAPELFTGARPERLPV 831
HRDIK ++LL R K++D GFC E S+VGTP MAPE+ + RLP
Sbjct: 566 HRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRKSLVGTPYWMAPEVIS-----RLPY 620
Query: 832 FDE-ECWQL 839
E + W L
Sbjct: 621 GTEVDIWSL 629
>gi|148746218 TAO kinase 3 [Homo sapiens]
Length = 898
Score = 67.4 bits (163), Expect = 6e-11
Identities = 59/206 (28%), Positives = 85/206 (41%), Gaps = 16/206 (7%)
Query: 657 ELGRGQYGVVYLCDNWGGHFPCALKSVV---PPDEKHWNDLALEFHYMRSLPKHERLVDL 713
E+G G +G VY N A+K + + W D+ E ++R L KH ++
Sbjct: 29 EIGHGSFGAVYFATNAHTSEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQL-KHPNTIEY 87
Query: 714 HGSVIDYNYGGGSSIAVLLIMERL---HRDLYTGLKAGLTLETRLQIALDVVEGIRFLHS 770
G + + L+ME DL K L I + G+ +LHS
Sbjct: 88 KGCYLKEH-------TAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALHGLAYLHS 140
Query: 771 QGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGARPERLP 830
L+HRDIK N+LL + + K+ D G A + S VGTP MAPE+ A E
Sbjct: 141 HALIHRDIKAGNILLTEPGQVKLADFGSAS-MASPANSFVGTPYWMAPEVIL-AMDEGQY 198
Query: 831 VFDEECWQLMEACWDGDPLKRPLLGI 856
+ W L C + K PL +
Sbjct: 199 DGKVDIWSLGITCIELAERKPPLFNM 224
>gi|223671888 interleukin-1 receptor-associated kinase 4 isoform b
[Homo sapiens]
Length = 336
Score = 67.0 bits (162), Expect = 7e-11
Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 17/180 (9%)
Query: 655 GQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHY---MRSLPKHERLV 711
G ++G G +GVVY + + A+K + + +L +F + + +HE LV
Sbjct: 65 GNKMGEGGFGVVY--KGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLV 122
Query: 712 DLHGSVIDYNYGGGSSIAVLLIMER---LHRDLYTGLKAGLTLETRLQIALDVVEGIRFL 768
+L G ++ G V + M L R L+ R +IA GI FL
Sbjct: 123 ELLG----FSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFL 178
Query: 769 HSQGLVHRDIKLKNVLLDKQNRAKITDLGFCK-----PEAMMSGSIVGTPIHMAPELFTG 823
H +HRDIK N+LLD+ AKI+D G + + +M+ IVGT +MAPE G
Sbjct: 179 HENHHIHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRG 238
>gi|223671885 interleukin-1 receptor-associated kinase 4 isoform b
[Homo sapiens]
Length = 336
Score = 67.0 bits (162), Expect = 7e-11
Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 17/180 (9%)
Query: 655 GQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHY---MRSLPKHERLV 711
G ++G G +GVVY + + A+K + + +L +F + + +HE LV
Sbjct: 65 GNKMGEGGFGVVY--KGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLV 122
Query: 712 DLHGSVIDYNYGGGSSIAVLLIMER---LHRDLYTGLKAGLTLETRLQIALDVVEGIRFL 768
+L G ++ G V + M L R L+ R +IA GI FL
Sbjct: 123 ELLG----FSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFL 178
Query: 769 HSQGLVHRDIKLKNVLLDKQNRAKITDLGFCK-----PEAMMSGSIVGTPIHMAPELFTG 823
H +HRDIK N+LLD+ AKI+D G + + +M+ IVGT +MAPE G
Sbjct: 179 HENHHIHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRG 238
>gi|223671883 interleukin-1 receptor-associated kinase 4 isoform b
[Homo sapiens]
Length = 336
Score = 67.0 bits (162), Expect = 7e-11
Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 17/180 (9%)
Query: 655 GQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHY---MRSLPKHERLV 711
G ++G G +GVVY + + A+K + + +L +F + + +HE LV
Sbjct: 65 GNKMGEGGFGVVY--KGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLV 122
Query: 712 DLHGSVIDYNYGGGSSIAVLLIMER---LHRDLYTGLKAGLTLETRLQIALDVVEGIRFL 768
+L G ++ G V + M L R L+ R +IA GI FL
Sbjct: 123 ELLG----FSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFL 178
Query: 769 HSQGLVHRDIKLKNVLLDKQNRAKITDLGFCK-----PEAMMSGSIVGTPIHMAPELFTG 823
H +HRDIK N+LLD+ AKI+D G + + +M+ IVGT +MAPE G
Sbjct: 179 HENHHIHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRG 238
>gi|166795293 interleukin-1 receptor-associated kinase 4 isoform a
[Homo sapiens]
Length = 460
Score = 67.0 bits (162), Expect = 7e-11
Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 17/180 (9%)
Query: 655 GQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHY---MRSLPKHERLV 711
G ++G G +GVVY + + A+K + + +L +F + + +HE LV
Sbjct: 189 GNKMGEGGFGVVY--KGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLV 246
Query: 712 DLHGSVIDYNYGGGSSIAVLLIMER---LHRDLYTGLKAGLTLETRLQIALDVVEGIRFL 768
+L G ++ G V + M L R L+ R +IA GI FL
Sbjct: 247 ELLG----FSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFL 302
Query: 769 HSQGLVHRDIKLKNVLLDKQNRAKITDLGFCK-----PEAMMSGSIVGTPIHMAPELFTG 823
H +HRDIK N+LLD+ AKI+D G + + +M+ IVGT +MAPE G
Sbjct: 303 HENHHIHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRG 362
>gi|166795295 interleukin-1 receptor-associated kinase 4 isoform a
[Homo sapiens]
Length = 460
Score = 67.0 bits (162), Expect = 7e-11
Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 17/180 (9%)
Query: 655 GQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHY---MRSLPKHERLV 711
G ++G G +GVVY + + A+K + + +L +F + + +HE LV
Sbjct: 189 GNKMGEGGFGVVY--KGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAKCQHENLV 246
Query: 712 DLHGSVIDYNYGGGSSIAVLLIMER---LHRDLYTGLKAGLTLETRLQIALDVVEGIRFL 768
+L G ++ G V + M L R L+ R +IA GI FL
Sbjct: 247 ELLG----FSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGINFL 302
Query: 769 HSQGLVHRDIKLKNVLLDKQNRAKITDLGFCK-----PEAMMSGSIVGTPIHMAPELFTG 823
H +HRDIK N+LLD+ AKI+D G + + +M+ IVGT +MAPE G
Sbjct: 303 HENHHIHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEALRG 362
>gi|47157325 protein kinase C, delta [Homo sapiens]
Length = 676
Score = 65.1 bits (157), Expect = 3e-10
Identities = 29/71 (40%), Positives = 46/71 (64%), Gaps = 3/71 (4%)
Query: 758 ALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAM---MSGSIVGTPI 814
A +++ G++FLHS+G+++RD+KL NVLLD+ KI D G CK + + GTP
Sbjct: 454 AAEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPD 513
Query: 815 HMAPELFTGAR 825
++APE+ G +
Sbjct: 514 YIAPEILQGLK 524
>gi|31377782 protein kinase C, delta [Homo sapiens]
Length = 676
Score = 65.1 bits (157), Expect = 3e-10
Identities = 29/71 (40%), Positives = 46/71 (64%), Gaps = 3/71 (4%)
Query: 758 ALDVVEGIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAM---MSGSIVGTPI 814
A +++ G++FLHS+G+++RD+KL NVLLD+ KI D G CK + + GTP
Sbjct: 454 AAEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPD 513
Query: 815 HMAPELFTGAR 825
++APE+ G +
Sbjct: 514 YIAPEILQGLK 524
>gi|134288915 myosin IIIB isoform 1 [Homo sapiens]
Length = 1314
Score = 63.5 bits (153), Expect = 8e-10
Identities = 55/206 (26%), Positives = 91/206 (44%), Gaps = 15/206 (7%)
Query: 656 QELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHG 715
+ +G+G YG VY N A+K + P + ++ E++ ++ LP H +V +G
Sbjct: 31 ETIGKGTYGKVYKVTNKRDGSLAAVKILDPVSDMD-EEIEAEYNILQFLPNHPNVVKFYG 89
Query: 716 SVI--DYNYGGGSSIAVLLIMERLHRDLYTGL-KAGLTLETRL--QIALDVVEGIRFLHS 770
D+ GG + + L +L GL + G L+ + I + G++ LH+
Sbjct: 90 MFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMISYILYGALLGLQHLHN 149
Query: 771 QGLVHRDIKLKNVLLDKQNRAKITDLGF---CKPEAMMSGSIVGTPIHMAPELFTGARPE 827
++HRD+K N+LL + K+ D G + + VGTP MAPE+ +
Sbjct: 150 NRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVI-ACEQQ 208
Query: 828 RLPVFDEEC--WQL---MEACWDGDP 848
+D C W L DGDP
Sbjct: 209 YDSSYDARCDVWSLGITAIELGDGDP 234
>gi|134288892 myosin IIIB isoform 2 [Homo sapiens]
Length = 1341
Score = 63.5 bits (153), Expect = 8e-10
Identities = 55/206 (26%), Positives = 91/206 (44%), Gaps = 15/206 (7%)
Query: 656 QELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHG 715
+ +G+G YG VY N A+K + P + ++ E++ ++ LP H +V +G
Sbjct: 31 ETIGKGTYGKVYKVTNKRDGSLAAVKILDPVSDMD-EEIEAEYNILQFLPNHPNVVKFYG 89
Query: 716 SVI--DYNYGGGSSIAVLLIMERLHRDLYTGL-KAGLTLETRL--QIALDVVEGIRFLHS 770
D+ GG + + L +L GL + G L+ + I + G++ LH+
Sbjct: 90 MFYKADHCVGGQLWLVLELCNGGSVTELVKGLLRCGQRLDEAMISYILYGALLGLQHLHN 149
Query: 771 QGLVHRDIKLKNVLLDKQNRAKITDLGF---CKPEAMMSGSIVGTPIHMAPELFTGARPE 827
++HRD+K N+LL + K+ D G + + VGTP MAPE+ +
Sbjct: 150 NRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVI-ACEQQ 208
Query: 828 RLPVFDEEC--WQL---MEACWDGDP 848
+D C W L DGDP
Sbjct: 209 YDSSYDARCDVWSLGITAIELGDGDP 234
>gi|4506067 protein kinase C, alpha [Homo sapiens]
Length = 672
Score = 63.2 bits (152), Expect = 1e-09
Identities = 55/177 (31%), Positives = 83/177 (46%), Gaps = 26/177 (14%)
Query: 658 LGRGQYGVVYLCDNWGGHFPCALKS-----VVPPDEKHWNDLALEFHYMRSLPKHERLVD 712
LG+G +G V L D G A+K V+ D+ +E + L K L
Sbjct: 345 LGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECT--MVEKRVLALLDKPPFLTQ 402
Query: 713 LHG--SVIDYNYGGGSSIAVLLIMERLHRD--LYTGLKAGLTLETRLQI-ALDVVEGIRF 767
LH +D Y +ME ++ +Y + G E + A ++ G+ F
Sbjct: 403 LHSCFQTVDRLY---------FVMEYVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFF 453
Query: 768 LHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSG----SIVGTPIHMAPEL 820
LH +G+++RD+KL NV+LD + KI D G CK E MM G + GTP ++APE+
Sbjct: 454 LHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCK-EHMMDGVTTRTFCGTPDYIAPEI 509
>gi|47132591 protein kinase N1 isoform 1 [Homo sapiens]
Length = 948
Score = 62.8 bits (151), Expect = 1e-09
Identities = 56/183 (30%), Positives = 86/183 (46%), Gaps = 33/183 (18%)
Query: 658 LGRGQYGVVYLCDNWGGHFPCALKSVVPPD---EKHWNDLALEFHYMRSLPK--HERLVD 712
LGRG +G V L + A+K++ D L E + ++ H LV+
Sbjct: 627 LGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTSAGHPFLVN 686
Query: 713 LHGS---------VIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIALDVVE 763
L G V++Y+ GG +M +H D+++ +A + + VV
Sbjct: 687 LFGCFQTPEHVCFVMEYSAGGD-------LMLHIHSDVFSEPRA-------IFYSACVVL 732
Query: 764 GIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSG----SIVGTPIHMAPE 819
G++FLH +V+RD+KL N+LLD + KI D G CK E M G + GTP +APE
Sbjct: 733 GLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCK-EGMGYGDRTSTFCGTPEFLAPE 791
Query: 820 LFT 822
+ T
Sbjct: 792 VLT 794
>gi|47132589 protein kinase N1 isoform 2 [Homo sapiens]
Length = 942
Score = 62.8 bits (151), Expect = 1e-09
Identities = 56/183 (30%), Positives = 86/183 (46%), Gaps = 33/183 (18%)
Query: 658 LGRGQYGVVYLCDNWGGHFPCALKSVVPPD---EKHWNDLALEFHYMRSLPK--HERLVD 712
LGRG +G V L + A+K++ D L E + ++ H LV+
Sbjct: 621 LGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTSAGHPFLVN 680
Query: 713 LHGS---------VIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIALDVVE 763
L G V++Y+ GG +M +H D+++ +A + + VV
Sbjct: 681 LFGCFQTPEHVCFVMEYSAGGD-------LMLHIHSDVFSEPRA-------IFYSACVVL 726
Query: 764 GIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSG----SIVGTPIHMAPE 819
G++FLH +V+RD+KL N+LLD + KI D G CK E M G + GTP +APE
Sbjct: 727 GLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCK-EGMGYGDRTSTFCGTPEFLAPE 785
Query: 820 LFT 822
+ T
Sbjct: 786 VLT 788
>gi|133908623 protein kinase C, iota [Homo sapiens]
Length = 596
Score = 62.4 bits (150), Expect = 2e-09
Identities = 53/182 (29%), Positives = 82/182 (45%), Gaps = 30/182 (16%)
Query: 658 LGRGQYGVVYLCDNWGGHFPCALKSV---VPPDEKHWNDLALEFHYMRSLPKHERLVDLH 714
+GRG Y V L A+K V + D++ + + E H H LV LH
Sbjct: 260 IGRGSYAKVLLVRLKKTDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFLVGLH 319
Query: 715 GS---------VIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIALDVVEGI 765
VI+Y GG ++ M+R + L E + ++ +
Sbjct: 320 SCFQTESRLFFVIEYVNGGD----LMFHMQRQRK---------LPEEHARFYSAEISLAL 366
Query: 766 RFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSG----SIVGTPIHMAPELF 821
+LH +G+++RD+KL NVLLD + K+TD G CK E + G + GTP ++APE+
Sbjct: 367 NYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCK-EGLRPGDTTSTFCGTPNYIAPEIL 425
Query: 822 TG 823
G
Sbjct: 426 RG 427
>gi|45439370 TAO kinase 1 [Homo sapiens]
Length = 1001
Score = 62.4 bits (150), Expect = 2e-09
Identities = 56/213 (26%), Positives = 88/213 (41%), Gaps = 28/213 (13%)
Query: 656 QELGRGQYGVVYLCDNWGGHFPCALKSVV---PPDEKHWNDLALEFHYMRSLPKHERLVD 712
+E+G G +G VY + + A+K + + W D+ E +++ + KH ++
Sbjct: 32 REIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRI-KHPNSIE 90
Query: 713 LHGS---------VIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLTLETRLQIALDVVE 763
G V++Y G S DL K L I ++
Sbjct: 91 YKGCYLREHTAWLVMEYCLGSAS-------------DLLEVHKKPLQEVEIAAITHGALQ 137
Query: 764 GIRFLHSQGLVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTG 823
G+ +LHS ++HRDIK N+LL + + K+ D G A + S VGTP MAPE+
Sbjct: 138 GLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSAS-MASPANSFVGTPYWMAPEVIL- 195
Query: 824 ARPERLPVFDEECWQLMEACWDGDPLKRPLLGI 856
A E + W L C + K PL +
Sbjct: 196 AMDEGQYDGKVDVWSLGITCIELAERKPPLFNM 228
>gi|191252782 p21-activated kinase 6 [Homo sapiens]
Length = 681
Score = 62.4 bits (150), Expect = 2e-09
Identities = 62/235 (26%), Positives = 101/235 (42%), Gaps = 31/235 (13%)
Query: 657 ELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMRSLPKHERLVDLHGS 716
++G G G+V L A+K + ++ L E MR +H +V+++ S
Sbjct: 412 KIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDY-QHFNVVEMYKS 470
Query: 717 VIDYNYGGGSSIAVLLIMERLHRDLYTGLKAGLTL--ETRLQIALDVVEGIRFLHSQGLV 774
Y G + VL ME L T + + + L E + V++ + +LH+QG++
Sbjct: 471 -----YLVGEELWVL--MEFLQGGALTDIVSQVRLNEEQIATVCEAVLQALAYLHAQGVI 523
Query: 775 HRDIKLKNVLLDKQNRAKITDLGFC---KPEAMMSGSIVGTPIHMAPELFTGAR------ 825
HRDIK ++LL R K++D GFC + S+VGTP MAPE+ + +
Sbjct: 524 HRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVD 583
Query: 826 ------------PERLPVFDEECWQLMEACWDGDPLKRPLLGIVQPMLQGIMNRL 868
P F + Q M+ D P K V P+L+ + R+
Sbjct: 584 IWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSHKVSPVLRDFLERM 638
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,517,156
Number of Sequences: 37866
Number of extensions: 1592937
Number of successful extensions: 6371
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 667
Number of HSP's successfully gapped in prelim test: 138
Number of HSP's that attempted gapping in prelim test: 4974
Number of HSP's gapped (non-prelim): 1215
length of query: 884
length of database: 18,247,518
effective HSP length: 111
effective length of query: 773
effective length of database: 14,044,392
effective search space: 10856315016
effective search space used: 10856315016
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.