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Search of human proteins with 40786408
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40786408 SFT2 domain containing 2 [Homo sapiens]
(160 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40786408 SFT2 domain containing 2 [Homo sapiens] 324 2e-89
gi|21553317 SFT2 domain containing 1 [Homo sapiens] 213 6e-56
gi|15723380 transmembrane protein 54 [Homo sapiens] 32 0.23
gi|61635915 membrane-associated transporter protein isoform a [H... 29 1.5
gi|61636000 membrane-associated transporter protein isoform b [H... 29 1.5
gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo ... 28 2.6
gi|41327156 solute carrier family 16 (monocarboxylic acid transp... 28 3.4
gi|12965174 taste receptor, type 2, member 8 [Homo sapiens] 28 3.4
gi|31543076 transmembrane protein 217 isoform 1 [Homo sapiens] 28 4.4
gi|242332514 transmembrane protein 217 isoform 2 [Homo sapiens] 28 4.4
gi|4506163 presenilin 1 isoform I-467 [Homo sapiens] 28 4.4
gi|195947397 presenilin 1 isoform I-463 [Homo sapiens] 28 4.4
gi|57165359 WD repeat domain 89 [Homo sapiens] 28 4.4
gi|18087841 WD repeat domain 89 [Homo sapiens] 28 4.4
gi|6912500 phosphatidylinositol glycan anchor biosynthesis, clas... 27 5.7
gi|29029537 phosphatidylinositol glycan anchor biosynthesis, cla... 27 5.7
gi|4557759 myeloperoxidase [Homo sapiens] 27 7.5
gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens] 27 7.5
gi|115270970 Mid-1-related chloride channel 1 isoform 1 [Homo sa... 27 9.8
gi|13194195 Mid-1-related chloride channel 1 isoform 2 [Homo sap... 27 9.8
>gi|40786408 SFT2 domain containing 2 [Homo sapiens]
Length = 160
Score = 324 bits (830), Expect = 2e-89
Identities = 160/160 (100%), Positives = 160/160 (100%)
Query: 1 MDKLKKVLSGQDTEDRSGLSEVVEASSLSWSTRIKGFIACFAIGILCSLLGTVLLWVPRK 60
MDKLKKVLSGQDTEDRSGLSEVVEASSLSWSTRIKGFIACFAIGILCSLLGTVLLWVPRK
Sbjct: 1 MDKLKKVLSGQDTEDRSGLSEVVEASSLSWSTRIKGFIACFAIGILCSLLGTVLLWVPRK 60
Query: 61 GLHLFAVFYTFGNIASIGSTIFLMGPVKQLKRMFEPTRLIATIMVLLCFALTLCSAFWWH 120
GLHLFAVFYTFGNIASIGSTIFLMGPVKQLKRMFEPTRLIATIMVLLCFALTLCSAFWWH
Sbjct: 61 GLHLFAVFYTFGNIASIGSTIFLMGPVKQLKRMFEPTRLIATIMVLLCFALTLCSAFWWH 120
Query: 121 NKGLALIFCILQSLALTWYSLSFIPFARDAVKKCFAVCLA 160
NKGLALIFCILQSLALTWYSLSFIPFARDAVKKCFAVCLA
Sbjct: 121 NKGLALIFCILQSLALTWYSLSFIPFARDAVKKCFAVCLA 160
>gi|21553317 SFT2 domain containing 1 [Homo sapiens]
Length = 159
Score = 213 bits (542), Expect = 6e-56
Identities = 100/160 (62%), Positives = 132/160 (82%), Gaps = 1/160 (0%)
Query: 1 MDKLKKVLSGQDTEDRSGLSEVVEASSLSWSTRIKGFIACFAIGILCSLLGTVLLWVPRK 60
M+KL++VLSGQD E++ ++V++ASSLS++TR+K F CF G+ S+LGT LLW+P
Sbjct: 1 MEKLRRVLSGQDDEEQGLTAQVLDASSLSFNTRLKWFAICFVCGVFFSILGTGLLWLPG- 59
Query: 61 GLHLFAVFYTFGNIASIGSTIFLMGPVKQLKRMFEPTRLIATIMVLLCFALTLCSAFWWH 120
G+ LFAVFYT GN+A++ ST FLMGPVKQLK+MFE TRL+ATI++LLCF TLC+A WWH
Sbjct: 60 GIKLFAVFYTLGNLAALASTCFLMGPVKQLKKMFEATRLLATIVMLLCFIFTLCAALWWH 119
Query: 121 NKGLALIFCILQSLALTWYSLSFIPFARDAVKKCFAVCLA 160
KGLA++FCILQ L++TWYSLS+IP+ARDAV KC + L+
Sbjct: 120 KKGLAVLFCILQFLSMTWYSLSYIPYARDAVIKCCSSLLS 159
>gi|15723380 transmembrane protein 54 [Homo sapiens]
Length = 222
Score = 32.0 bits (71), Expect = 0.23
Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 13/100 (13%)
Query: 19 LSEVVEASSLSWSTRIKGFIACFAIGILCSL--LGTVLLWVPRKGLHLFAVFYTFGNIAS 76
LS + ++ L W T +AC + + C+L L ++ + +G L A TFG+
Sbjct: 81 LSRYLPSTPLRW-TVFSSSVACALLSLTCALGLLASIAMTFATQGKALLAAC-TFGS--- 135
Query: 77 IGSTIFLMGPVKQLKRMFEPTRLIATIMVLLCFALTLCSA 116
S + + P F+PTR+ ++ + L AL LC A
Sbjct: 136 --SELLALAP----DCPFDPTRIYSSSLCLWGIALVLCVA 169
>gi|61635915 membrane-associated transporter protein isoform a [Homo
sapiens]
Length = 530
Score = 29.3 bits (64), Expect = 1.5
Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 13/64 (20%)
Query: 60 KGLHLFAVFYTFGNIASIGSTIFLMGPVK----QLKRM----FEPTRLIATIMVLLCFAL 111
KGLH A+F FG G+ +L+G + +L R+ F+ + +++ LCF +
Sbjct: 178 KGLHYHALFTGFG-----GALGYLLGAIDWAHLELGRLLGTEFQVMFFFSALVLTLCFTV 232
Query: 112 TLCS 115
LCS
Sbjct: 233 HLCS 236
>gi|61636000 membrane-associated transporter protein isoform b [Homo
sapiens]
Length = 460
Score = 29.3 bits (64), Expect = 1.5
Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 13/64 (20%)
Query: 60 KGLHLFAVFYTFGNIASIGSTIFLMGPVK----QLKRM----FEPTRLIATIMVLLCFAL 111
KGLH A+F FG G+ +L+G + +L R+ F+ + +++ LCF +
Sbjct: 178 KGLHYHALFTGFG-----GALGYLLGAIDWAHLELGRLLGTEFQVMFFFSALVLTLCFTV 232
Query: 112 TLCS 115
LCS
Sbjct: 233 HLCS 236
>gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo
sapiens]
Length = 97
Score = 28.5 bits (62), Expect = 2.6
Identities = 11/51 (21%), Positives = 25/51 (49%)
Query: 90 LKRMFEPTRLIATIMVLLCFALTLCSAFWWHNKGLALIFCILQSLALTWYS 140
+ + F L++ I++ L + WW +G+ + C + + L+WY+
Sbjct: 1 MAKSFPVFSLLSFILIHLVLSSVSGPRHWWPPRGIIKVKCPYEKVNLSWYN 51
>gi|41327156 solute carrier family 16 (monocarboxylic acid
transporters), member 14 [Homo sapiens]
Length = 510
Score = 28.1 bits (61), Expect = 3.4
Identities = 30/124 (24%), Positives = 49/124 (39%), Gaps = 23/124 (18%)
Query: 18 GLSEVVEASSLSWSTRIKGFIACFA----------IGILCSLLGTVLLWVPRKGLHLFAV 67
GL+ V + S+ + + FI F IG L + LG VL ++ +
Sbjct: 70 GLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVL---SAYAANVHYL 126
Query: 68 FYTFGNIASIGSTIFLMGPVKQLKRMFEPTRLIAT----------IMVLLCFALTLCSAF 117
F TFG A +GS + + V + R F+ R +A ++ LC+ +
Sbjct: 127 FITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEY 186
Query: 118 WWHN 121
W N
Sbjct: 187 GWRN 190
>gi|12965174 taste receptor, type 2, member 8 [Homo sapiens]
Length = 309
Score = 28.1 bits (61), Expect = 3.4
Identities = 27/94 (28%), Positives = 38/94 (40%), Gaps = 16/94 (17%)
Query: 38 IACFAIGILCSLLGTVLLWVPRKGLHLFAVFYTFGNIASIGSTIFLMGPVKQLKRMFEPT 97
+ CFAI +L SL+ ++L + Y F IA I M V ++ FEP
Sbjct: 135 LGCFAISLLVSLIAAIVL----------SCDYRFHAIAKHKRNITEMFHVSKIP-YFEPL 183
Query: 98 RL-----IATIMVLLCFALTLCSAFWWHNKGLAL 126
L I +V L L + W H K + L
Sbjct: 184 TLFNLFAIVPFIVSLISFFLLVRSLWRHTKQIKL 217
>gi|31543076 transmembrane protein 217 isoform 1 [Homo sapiens]
Length = 229
Score = 27.7 bits (60), Expect = 4.4
Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Query: 18 GLSEVVEASSLSWSTRIKGFIACFAIGILCSLLGTVLLWVPRKGLHLFAVFYTFGNIASI 77
G S ++ + WS +I F++ I I C LL +V + R GL ++ V+ F A++
Sbjct: 51 GASNIINNFIICWSFKIVLFLSFITILISCFLLYSVYAQIFR-GLVIYIVWIFFYETANV 109
>gi|242332514 transmembrane protein 217 isoform 2 [Homo sapiens]
Length = 202
Score = 27.7 bits (60), Expect = 4.4
Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Query: 18 GLSEVVEASSLSWSTRIKGFIACFAIGILCSLLGTVLLWVPRKGLHLFAVFYTFGNIASI 77
G S ++ + WS +I F++ I I C LL +V + R GL ++ V+ F A++
Sbjct: 51 GASNIINNFIICWSFKIVLFLSFITILISCFLLYSVYAQIFR-GLVIYIVWIFFYETANV 109
>gi|4506163 presenilin 1 isoform I-467 [Homo sapiens]
Length = 467
Score = 27.7 bits (60), Expect = 4.4
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 17/79 (21%)
Query: 7 VLSGQDTEDRS---GLSEVVEASSL----------SWSTRIKGFIACFAIGILCSLLGTV 53
+L+G+D E+R GL + + S L W+T I ACF ++ L +
Sbjct: 368 ILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTI----ACFVAILIGLCLTLL 423
Query: 54 LLWVPRKGLHLFAVFYTFG 72
LL + +K L + TFG
Sbjct: 424 LLAIFKKALPALPISITFG 442
>gi|195947397 presenilin 1 isoform I-463 [Homo sapiens]
Length = 463
Score = 27.7 bits (60), Expect = 4.4
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 17/79 (21%)
Query: 7 VLSGQDTEDRS---GLSEVVEASSL----------SWSTRIKGFIACFAIGILCSLLGTV 53
+L+G+D E+R GL + + S L W+T I ACF ++ L +
Sbjct: 364 ILAGEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTI----ACFVAILIGLCLTLL 419
Query: 54 LLWVPRKGLHLFAVFYTFG 72
LL + +K L + TFG
Sbjct: 420 LLAIFKKALPALPISITFG 438
>gi|57165359 WD repeat domain 89 [Homo sapiens]
Length = 387
Score = 27.7 bits (60), Expect = 4.4
Identities = 10/41 (24%), Positives = 19/41 (46%)
Query: 104 MVLLCFALTLCSAFWWHNKGLALIFCILQSLALTWYSLSFI 144
+V C +++ S W KG I+C+ W+ L+ +
Sbjct: 209 LVTTCNSISSVSCIGWSGKGYKQIYCMTHDEGFYWWDLNHL 249
>gi|18087841 WD repeat domain 89 [Homo sapiens]
Length = 387
Score = 27.7 bits (60), Expect = 4.4
Identities = 10/41 (24%), Positives = 19/41 (46%)
Query: 104 MVLLCFALTLCSAFWWHNKGLALIFCILQSLALTWYSLSFI 144
+V C +++ S W KG I+C+ W+ L+ +
Sbjct: 209 LVTTCNSISSVSCIGWSGKGYKQIYCMTHDEGFYWWDLNHL 249
>gi|6912500 phosphatidylinositol glycan anchor biosynthesis, class N
[Homo sapiens]
Length = 931
Score = 27.3 bits (59), Expect = 5.7
Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
Query: 64 LFAVFYTFGNIASIGSTIFLMGPVKQLKRMFEPTRLIATIM--VLLCFALTLCS 115
L F+ GNIASI S F + V +F P + A +M +L+ F L +C+
Sbjct: 794 LVTAFFGTGNIASINS--FDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCA 845
>gi|29029537 phosphatidylinositol glycan anchor biosynthesis, class
N [Homo sapiens]
Length = 931
Score = 27.3 bits (59), Expect = 5.7
Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
Query: 64 LFAVFYTFGNIASIGSTIFLMGPVKQLKRMFEPTRLIATIM--VLLCFALTLCS 115
L F+ GNIASI S F + V +F P + A +M +L+ F L +C+
Sbjct: 794 LVTAFFGTGNIASINS--FDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCA 845
>gi|4557759 myeloperoxidase [Homo sapiens]
Length = 745
Score = 26.9 bits (58), Expect = 7.5
Identities = 32/94 (34%), Positives = 42/94 (44%), Gaps = 13/94 (13%)
Query: 50 LGTVL--LWVPRKGLHLFAVFYTFGNIASIGSTIFLMGPVKQLKRMFEPTRLIATIMVLL 107
LGTVL L + RK L + T NI I++ G + LKR L+A I+
Sbjct: 617 LGTVLRNLKLARK---LMEQYGTPNNI-----DIWMGGVSEPLKRKGRVGPLLACIIGTQ 668
Query: 108 CFALTLCSAFWWHNKGLALIFCILQSLALTWYSL 141
L FWW N+G +F + Q AL SL
Sbjct: 669 FRKLRDGDRFWWENEG---VFSMQQRQALAQISL 699
>gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens]
Length = 2459
Score = 26.9 bits (58), Expect = 7.5
Identities = 19/73 (26%), Positives = 41/73 (56%), Gaps = 7/73 (9%)
Query: 32 TRIKGFIACFAIGILCSLLGTVLLW-VPR----KGLHLFAVFYTFGNIASIGSTIFLMGP 86
TR++ CF++ +LC++L +++ W VP+ + + L + +T+ + + LM P
Sbjct: 1548 TRVQRVSCCFSL-LLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFP 1606
Query: 87 VKQL-KRMFEPTR 98
+ L ++F+ TR
Sbjct: 1607 INLLIVQIFQNTR 1619
>gi|115270970 Mid-1-related chloride channel 1 isoform 1 [Homo
sapiens]
Length = 551
Score = 26.6 bits (57), Expect = 9.8
Identities = 15/59 (25%), Positives = 27/59 (45%), Gaps = 5/59 (8%)
Query: 95 EPTRLIATIMVLLCFALTLCSAFW----WHNK-GLALIFCILQSLALTWYSLSFIPFAR 148
+P ++ ++ LLC + + + W W+ + LI L SL W L + FA+
Sbjct: 181 DPYNVLMVLLCLLCIVVLVATELWTYVRWYTQLRRVLIISFLFSLGWNWMYLYKLAFAQ 239
>gi|13194195 Mid-1-related chloride channel 1 isoform 2 [Homo
sapiens]
Length = 501
Score = 26.6 bits (57), Expect = 9.8
Identities = 15/59 (25%), Positives = 27/59 (45%), Gaps = 5/59 (8%)
Query: 95 EPTRLIATIMVLLCFALTLCSAFW----WHNK-GLALIFCILQSLALTWYSLSFIPFAR 148
+P ++ ++ LLC + + + W W+ + LI L SL W L + FA+
Sbjct: 131 DPYNVLMVLLCLLCIVVLVATELWTYVRWYTQLRRVLIISFLFSLGWNWMYLYKLAFAQ 189
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.331 0.141 0.457
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,329,569
Number of Sequences: 37866
Number of extensions: 188099
Number of successful extensions: 591
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 583
Number of HSP's gapped (non-prelim): 21
length of query: 160
length of database: 18,247,518
effective HSP length: 94
effective length of query: 66
effective length of database: 14,688,114
effective search space: 969415524
effective search space used: 969415524
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.