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Search of human proteins with 40316918
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40316918 NOL1/NOP2/Sun domain family 4 protein [Homo
sapiens]
(384 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40316918 NOL1/NOP2/Sun domain family 4 protein [Homo sapiens] 780 0.0
gi|11545785 NOL1/NOP2/Sun domain family, member 3 [Homo sapiens] 173 2e-43
gi|76150625 nucleolar protein 1, 120kDa [Homo sapiens] 81 2e-15
gi|76150623 nucleolar protein 1, 120kDa [Homo sapiens] 81 2e-15
gi|32698918 NOL1/NOP2/Sun domain family, member 6 [Homo sapiens] 68 1e-11
gi|39995082 NOL1/NOP2/Sun domain family, member 2 [Homo sapiens] 67 2e-11
gi|23199998 NOL1/NOP2/Sun domain family, member 5 isoform 1 [Hom... 49 1e-05
gi|8922322 NOL1/NOP2/Sun domain family, member 5 isoform 2 [Homo... 49 1e-05
gi|165377209 methyltransferase 5 domain containing 1 isoform 1 [... 32 0.74
gi|165377202 methyltransferase 5 domain containing 1 isoform 2 [... 32 0.74
gi|4502175 apical protein of Xenopus-like [Homo sapiens] 31 2.1
gi|7662236 TSC22 domain family, member 2 [Homo sapiens] 30 3.7
gi|13540600 nudE nuclear distribution gene E homolog (A. nidulan... 29 6.2
gi|187828635 NOL1/NOP2/Sun domain family, member 7 [Homo sapiens] 29 6.2
>gi|40316918 NOL1/NOP2/Sun domain family 4 protein [Homo sapiens]
Length = 384
Score = 780 bits (2014), Expect = 0.0
Identities = 384/384 (100%), Positives = 384/384 (100%)
Query: 1 MAALTLRGVRELLKRVDLATVPRRHRYKKKWAATEPKFPAVRLALQNFDMTYSVQFGDLW 60
MAALTLRGVRELLKRVDLATVPRRHRYKKKWAATEPKFPAVRLALQNFDMTYSVQFGDLW
Sbjct: 1 MAALTLRGVRELLKRVDLATVPRRHRYKKKWAATEPKFPAVRLALQNFDMTYSVQFGDLW 60
Query: 61 PSIRVSLLSEQKYGALVNNFAAWDHVSAKLEQLSAKDFVNEAISHWELQSEGGQSAAPSP 120
PSIRVSLLSEQKYGALVNNFAAWDHVSAKLEQLSAKDFVNEAISHWELQSEGGQSAAPSP
Sbjct: 61 PSIRVSLLSEQKYGALVNNFAAWDHVSAKLEQLSAKDFVNEAISHWELQSEGGQSAAPSP 120
Query: 121 ASWACSPNLRCFTFDRGDISRFPPARPGSLGVMEYYLMDAASLLPVLALGLQPGDIVLDL 180
ASWACSPNLRCFTFDRGDISRFPPARPGSLGVMEYYLMDAASLLPVLALGLQPGDIVLDL
Sbjct: 121 ASWACSPNLRCFTFDRGDISRFPPARPGSLGVMEYYLMDAASLLPVLALGLQPGDIVLDL 180
Query: 181 CAAPGGKTLALLQTGCCRNLAANDLSPSRIARLQKILHSYVPEEIRDGNQVRVTSWDGRK 240
CAAPGGKTLALLQTGCCRNLAANDLSPSRIARLQKILHSYVPEEIRDGNQVRVTSWDGRK
Sbjct: 181 CAAPGGKTLALLQTGCCRNLAANDLSPSRIARLQKILHSYVPEEIRDGNQVRVTSWDGRK 240
Query: 241 WGELEGDTYDRVLVDVPCTTDRHSLHEEENNIFKRSRKKERQILPVLQVQLLAAGLLATK 300
WGELEGDTYDRVLVDVPCTTDRHSLHEEENNIFKRSRKKERQILPVLQVQLLAAGLLATK
Sbjct: 241 WGELEGDTYDRVLVDVPCTTDRHSLHEEENNIFKRSRKKERQILPVLQVQLLAAGLLATK 300
Query: 301 PGGHVVYSTCSLSHLQNEYVVQGAIELLANQYSIQVQVEDLTHFRRVFMDTFCFFSSCQV 360
PGGHVVYSTCSLSHLQNEYVVQGAIELLANQYSIQVQVEDLTHFRRVFMDTFCFFSSCQV
Sbjct: 301 PGGHVVYSTCSLSHLQNEYVVQGAIELLANQYSIQVQVEDLTHFRRVFMDTFCFFSSCQV 360
Query: 361 GELVIPNLMANFGPMYFCKMRRLT 384
GELVIPNLMANFGPMYFCKMRRLT
Sbjct: 361 GELVIPNLMANFGPMYFCKMRRLT 384
>gi|11545785 NOL1/NOP2/Sun domain family, member 3 [Homo sapiens]
Length = 340
Score = 173 bits (439), Expect = 2e-43
Identities = 121/349 (34%), Positives = 191/349 (54%), Gaps = 42/349 (12%)
Query: 42 RLALQNFDMTYSVQFGDLWPSIRVSLLSEQ--KYGALVNNFAAWDHVSAKLEQLSAKDFV 99
++ L +F+ YS + GD W ++R L S +Y L+N F + +LE KD
Sbjct: 19 KVVLDHFEKQYSKELGDAWNTVREILTSPSCWQYAVLLNRF----NYPFELE----KDL- 69
Query: 100 NEAISHWELQSEGGQSAAPSPASWACSPNLRCFTFDRGDISRFP---PARPGSLG-VMEY 155
+ + S+G P +++C+ +SR P P+ +G + +Y
Sbjct: 70 --HLKGYHTLSQGSLPNYPK--------SVKCY------LSRTPGRIPSERHQIGNLKKY 113
Query: 156 YLMDAASLLPVLALGLQPGDIVLDLCAAPGGKTLALLQTGCCRNLAANDLSPSRIARLQK 215
YL++AASLLPVLAL L+ G+ VLDLCAAPGGK++ALLQ C L N+ R+ L++
Sbjct: 114 YLLNAASLLPVLALELRDGEKVLDLCAAPGGKSIALLQCACPGYLHCNEYDSLRLRWLRQ 173
Query: 216 ILHSYVPEEIRDGNQVRVTSWDGRKWGELEGDTYDRVLVDVPCTTDRHSLHEEENNIFKR 275
L S++P+ + N ++V+ DGRK G+ + + +D+VLVD PC+ DR L ++ K
Sbjct: 174 TLESFIPQPLI--NVIKVSELDGRKMGDAQPEMFDKVLVDAPCSNDRSWLFSSDSQ--KA 229
Query: 276 S-RKKERQILPVLQVQLLAAGLLATKPGGHVVYSTCSLSHLQNEYVVQGAIELLANQYSI 334
S R +R+ LP+LQ++LL + + A +PGG +VYSTC+LS +N+ V+ + N
Sbjct: 230 SCRISQRRNLPLLQIELLRSAIKALRPGGILVYSTCTLSKAENQDVISEILNSHGN---- 285
Query: 335 QVQVEDLTHFRRVFMDTFCFFSSCQ-VGELVIPNLMANFGPMYFCKMRR 382
+ D+ R F F + Q G LVIP+ +GPMY K+++
Sbjct: 286 -IMPMDIKGIARTCSHDFTFAPTGQECGLLVIPDKGKAWGPMYVAKLKK 333
>gi|76150625 nucleolar protein 1, 120kDa [Homo sapiens]
Length = 808
Score = 80.9 bits (198), Expect = 2e-15
Identities = 61/182 (33%), Positives = 100/182 (54%), Gaps = 24/182 (13%)
Query: 155 YYLMDAASLLPVLALGLQPGDIVLDLCAAPGGKTLALLQ----TGCCRNLAANDLSPSRI 210
Y L A+S+LPV+AL Q + +LD+C APGGKT + Q TG + AND + R+
Sbjct: 362 YMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYMAQLMKNTGV---ILANDANAERL 418
Query: 211 ARLQKILHSYVPEEIRDGNQVRVTSWDGRKWGELEGDTYDRVLVDVPCTTDRHSLHEEEN 270
+ LH + N + ++ +DGR++ ++ G +DRVL+D PC+
Sbjct: 419 KSVVGNLH-----RLGVTNTI-ISHYDGRQFPKVVGG-FDRVLLDAPCS----GTGVISK 467
Query: 271 NIFKRSRKKERQILPV--LQVQLLAAGL----LATKPGGHVVYSTCSLSHLQNEYVVQGA 324
+ ++ K E+ IL LQ +LL + + +K GG++VY TCS++ +NE+VV A
Sbjct: 468 DPAVKTNKDEKDILRCAHLQKELLLSAIDSVNATSKTGGYLVYCTCSITVEENEWVVDYA 527
Query: 325 IE 326
++
Sbjct: 528 LK 529
>gi|76150623 nucleolar protein 1, 120kDa [Homo sapiens]
Length = 808
Score = 80.9 bits (198), Expect = 2e-15
Identities = 61/182 (33%), Positives = 100/182 (54%), Gaps = 24/182 (13%)
Query: 155 YYLMDAASLLPVLALGLQPGDIVLDLCAAPGGKTLALLQ----TGCCRNLAANDLSPSRI 210
Y L A+S+LPV+AL Q + +LD+C APGGKT + Q TG + AND + R+
Sbjct: 362 YMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYMAQLMKNTGV---ILANDANAERL 418
Query: 211 ARLQKILHSYVPEEIRDGNQVRVTSWDGRKWGELEGDTYDRVLVDVPCTTDRHSLHEEEN 270
+ LH + N + ++ +DGR++ ++ G +DRVL+D PC+
Sbjct: 419 KSVVGNLH-----RLGVTNTI-ISHYDGRQFPKVVGG-FDRVLLDAPCS----GTGVISK 467
Query: 271 NIFKRSRKKERQILPV--LQVQLLAAGL----LATKPGGHVVYSTCSLSHLQNEYVVQGA 324
+ ++ K E+ IL LQ +LL + + +K GG++VY TCS++ +NE+VV A
Sbjct: 468 DPAVKTNKDEKDILRCAHLQKELLLSAIDSVNATSKTGGYLVYCTCSITVEENEWVVDYA 527
Query: 325 IE 326
++
Sbjct: 528 LK 529
>gi|32698918 NOL1/NOP2/Sun domain family, member 6 [Homo sapiens]
Length = 469
Score = 68.2 bits (165), Expect = 1e-11
Identities = 57/188 (30%), Positives = 88/188 (46%), Gaps = 34/188 (18%)
Query: 156 YLMDAASLLPVLALGLQPGDIVLDLCAAPGGKTLALLQTGCCRNLAANDLSPSRIARLQK 215
+L + S L L QPG+ +LDLCAAPGGKT ++AA + L K
Sbjct: 217 FLQNLPSALVSHVLNPQPGEKILDLCAAPGGKT---------THIAALMHDQGEVIALDK 267
Query: 216 ILHSYVPEEIRDG------NQVRVTSWDGRKWGELE------------GDTYDRVLVDVP 257
I + E+I+ N +R +DG K +L+ +++DR+L+D P
Sbjct: 268 IFNKV--EKIKQNALLLGLNSIRAFCFDGTKAVKLDMVEDTEGEPPFLPESFDRILLDAP 325
Query: 258 CTTDRHSLHEEENNIFKRSRKKERQILPVLQVQLLAAGLLATKPGGHVVYSTCSLSHLQN 317
C+ + + N S K+ P LQ +L A + KP G +VYSTC+++ +N
Sbjct: 326 CS----GMGQRPNMACTWSVKEVASYQP-LQRKLFTAAVQLLKPEGVLVYSTCTITLAEN 380
Query: 318 EYVVQGAI 325
E V A+
Sbjct: 381 EEQVAWAL 388
>gi|39995082 NOL1/NOP2/Sun domain family, member 2 [Homo sapiens]
Length = 767
Score = 67.4 bits (163), Expect = 2e-11
Identities = 63/240 (26%), Positives = 105/240 (43%), Gaps = 26/240 (10%)
Query: 107 ELQSEGGQSAAPSPASW-----ACSPNL-RCFTFDRGDISRFPPARPGSLGVMEYYLMDA 160
+L+ +G + P P SW A NL R + +F +A
Sbjct: 104 DLEVDGQKVEVPQPLSWYPEELAWHTNLSRKILRKSPHLEKFHQFLVSETESGNISRQEA 163
Query: 161 ASLLPVLALGLQPGDIVLDLCAAPGGKTLALLQTGCCRN--------LAANDLSPSR--- 209
S++P L L ++P +LD+CAAPG KT L++ + AND+ R
Sbjct: 164 VSMIPPLLLNVRPHHKILDMCAAPGSKTTQLIEMLHADMNVPFPEGFVIANDVDNKRCYL 223
Query: 210 -IARLQKILHSYVPEEIRDGNQVR--VTSWDGRKWGELEGDTYDRVLVDVPCTTDRHSLH 266
+ + +++ + D + + DGRK E YDR+L DVPC+ D
Sbjct: 224 LVHQAKRLSSPCIMVVNHDASSIPRLQIDVDGRK----EILFYDRILCDVPCSGD--GTM 277
Query: 267 EEENNIFKRSRKKERQILPVLQVQLLAAGLLATKPGGHVVYSTCSLSHLQNEYVVQGAIE 326
+ +++K+ L LQ+++ G GG +VYSTCSL+ +++E V+ +E
Sbjct: 278 RKNIDVWKKWTTLNSLQLHGLQLRIATRGAEQLAEGGRMVYSTCSLNPIEDEAVIASLLE 337
>gi|23199998 NOL1/NOP2/Sun domain family, member 5 isoform 1 [Homo
sapiens]
Length = 466
Score = 48.5 bits (114), Expect = 1e-05
Identities = 59/195 (30%), Positives = 84/195 (43%), Gaps = 21/195 (10%)
Query: 138 DISRFPPARPGSLGVMEYYLMDAASLLPVLALGLQPGDIVLDLCAAPGGKT---LALLQT 194
D+ P R G L L D AS LP + L PG V+D CAAPG KT ALL+
Sbjct: 196 DLHEHPLYRAGHL-----ILQDRASCLPAMLLDPPPGSHVIDACAAPGNKTSHLAALLKN 250
Query: 195 GCCRNLAANDLSPSRIARLQKILHSYVPE--EIRDGNQVRVTSWDGRKWGELEGDTYDRV 252
+ A DL R+A + +L E+ + + + V+ D R + E+ +
Sbjct: 251 Q--GKIFAFDLDAKRLASMATLLARAGVSCCELAEEDFLAVSPSDPR-YHEVH-----YI 302
Query: 253 LVDVPCTTDRHSLHEEENNIFKRSRKKERQILPVLQVQLLAAGLLATKPG-GHVVYSTCS 311
L+D C+ + E L Q + L L T P +VYSTCS
Sbjct: 303 LLDPSCSGSGMPSRQLEEPGAGTPSPVRLHALAGFQQRALCHAL--TFPSLQRLVYSTCS 360
Query: 312 LSHLQNEYVVQGAIE 326
L +NE VV+ A++
Sbjct: 361 LCQEENEDVVRDALQ 375
>gi|8922322 NOL1/NOP2/Sun domain family, member 5 isoform 2 [Homo
sapiens]
Length = 429
Score = 48.5 bits (114), Expect = 1e-05
Identities = 59/195 (30%), Positives = 84/195 (43%), Gaps = 21/195 (10%)
Query: 138 DISRFPPARPGSLGVMEYYLMDAASLLPVLALGLQPGDIVLDLCAAPGGKT---LALLQT 194
D+ P R G L L D AS LP + L PG V+D CAAPG KT ALL+
Sbjct: 196 DLHEHPLYRAGHL-----ILQDRASCLPAMLLDPPPGSHVIDACAAPGNKTSHLAALLKN 250
Query: 195 GCCRNLAANDLSPSRIARLQKILHSYVPE--EIRDGNQVRVTSWDGRKWGELEGDTYDRV 252
+ A DL R+A + +L E+ + + + V+ D R + E+ +
Sbjct: 251 Q--GKIFAFDLDAKRLASMATLLARAGVSCCELAEEDFLAVSPSDPR-YHEVH-----YI 302
Query: 253 LVDVPCTTDRHSLHEEENNIFKRSRKKERQILPVLQVQLLAAGLLATKPG-GHVVYSTCS 311
L+D C+ + E L Q + L L T P +VYSTCS
Sbjct: 303 LLDPSCSGSGMPSRQLEEPGAGTPSPVRLHALAGFQQRALCHAL--TFPSLQRLVYSTCS 360
Query: 312 LSHLQNEYVVQGAIE 326
L +NE VV+ A++
Sbjct: 361 LCQEENEDVVRDALQ 375
>gi|165377209 methyltransferase 5 domain containing 1 isoform 1
[Homo sapiens]
Length = 407
Score = 32.3 bits (72), Expect = 0.74
Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Query: 166 VLALGLQPGDIVLDLCAAPGGKTLALLQTGCCRNLAANDLSPSRIARLQKILHSYVPEEI 225
V L Q G I LD+ GG T A+LQ L A D P+ A + + Y P++I
Sbjct: 81 VHCLSPQKGQIFLDMTFGSGGHTKAILQKESDIVLYALDRDPTAYALAEHLSELY-PKQI 139
Query: 226 RDG-NQVRVTSWDGRKWGELEGDTYDRVLVDVPCTT 260
R Q K G G T+D VL+D+ C++
Sbjct: 140 RAMLGQFSQAEALLMKAGVQPG-TFDGVLMDLGCSS 174
>gi|165377202 methyltransferase 5 domain containing 1 isoform 2
[Homo sapiens]
Length = 273
Score = 32.3 bits (72), Expect = 0.74
Identities = 32/96 (33%), Positives = 44/96 (45%), Gaps = 3/96 (3%)
Query: 166 VLALGLQPGDIVLDLCAAPGGKTLALLQTGCCRNLAANDLSPSRIARLQKILHSYVPEEI 225
V L Q G I LD+ GG T A+LQ L A D P+ A + + Y P++I
Sbjct: 81 VHCLSPQKGQIFLDMTFGSGGHTKAILQKESDIVLYALDRDPTAYALAEHLSELY-PKQI 139
Query: 226 RDG-NQVRVTSWDGRKWGELEGDTYDRVLVDVPCTT 260
R Q K G G T+D VL+D+ C++
Sbjct: 140 RAMLGQFSQAEALLMKAGVQPG-TFDGVLMDLGCSS 174
>gi|4502175 apical protein of Xenopus-like [Homo sapiens]
Length = 1616
Score = 30.8 bits (68), Expect = 2.1
Identities = 20/82 (24%), Positives = 33/82 (40%), Gaps = 11/82 (13%)
Query: 70 EQKYGALVNNFAAWDHVSAKLEQLSAKDFVNEAISHWELQSEGGQSAAPSPASWACSPNL 129
+ YG+ + + DH +K + SA++ + + WE +GG+ A + L
Sbjct: 207 DSAYGSFSTSSSTPDHTLSKADTSSAENILY-TVGLWEAPRQGGRQAQAAGDPQGSEEKL 265
Query: 130 RCFTFDRGDISRFPPARPGSLG 151
C FPP PG G
Sbjct: 266 SC----------FPPRVPGDSG 277
>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
Length = 780
Score = 30.0 bits (66), Expect = 3.7
Identities = 20/53 (37%), Positives = 22/53 (41%), Gaps = 3/53 (5%)
Query: 110 SEGGQSAAPSPASWACSPNLRCFTFDRGDISRFPPARPGSLGVMEYYLMDAAS 162
S G +AAPS CS R D G P R G MEYY D+ S
Sbjct: 143 SAGPVTAAPSQPPTTCSSRFRVIKLDHGS---GEPYRRGRWTCMEYYERDSDS 192
>gi|13540600 nudE nuclear distribution gene E homolog (A.
nidulans)-like 1 isoform B [Homo sapiens]
Length = 345
Score = 29.3 bits (64), Expect = 6.2
Identities = 30/119 (25%), Positives = 51/119 (42%), Gaps = 23/119 (19%)
Query: 34 TEPKFPAVRLALQNFDMTYSVQFGDLWPSIRVSLLSE-----QKYGALVNNFAAWDHVSA 88
TE FP+ + F + L PS R+S L+ +K GAL + AA + +
Sbjct: 225 TENTFPSPKAIPNGFGTS------PLTPSARISALNIVGDLLRKVGALESKLAACRNFAK 278
Query: 89 KLEQLSAKDFVNEAISHWELQSEGGQSAAPSPASWACSPNLRCFTFDRGDISRFPPARP 147
+Q S K +++ ++ L G + + S+ FD+G ++ F PA P
Sbjct: 279 --DQASRKSYISGNVNCGVLNGNGTKFSRSGHTSF----------FDKGAVNGFDPAPP 325
>gi|187828635 NOL1/NOP2/Sun domain family, member 7 [Homo sapiens]
Length = 718
Score = 29.3 bits (64), Expect = 6.2
Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 12/102 (11%)
Query: 265 LHEEENNIFKRSRKK------ERQILPVLQVQLLAAGLLATKPGGHVVYSTCSLSHLQNE 318
L+E E+ F + + + +L Q + L + TK VVY TCS+ +NE
Sbjct: 389 LNEHEDTEFLKDHSQGGISVDKLHVLAQQQYEQLTHAMKFTKAQA-VVYCTCSVFPEENE 447
Query: 319 YVVQGAIEL--LANQ---YSIQVQVEDLTHFRRVFMDTFCFF 355
VV+ A+E L N+ Y + V L + + + T FF
Sbjct: 448 AVVKKALEFQDLGNKGQPYRLSPPVLPLCSLKEIQLSTDKFF 489
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,332,042
Number of Sequences: 37866
Number of extensions: 698235
Number of successful extensions: 1648
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1627
Number of HSP's gapped (non-prelim): 17
length of query: 384
length of database: 18,247,518
effective HSP length: 104
effective length of query: 280
effective length of database: 14,309,454
effective search space: 4006647120
effective search space used: 4006647120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.