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Search of human proteins with 38788135
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform
2 precursor [Homo sapiens]
(467 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 968 0.0
gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform ... 961 0.0
gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform... 939 0.0
gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precurso... 717 0.0
gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3 ... 656 0.0
gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon p... 409 e-114
gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precurs... 394 e-110
gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor... 384 e-107
gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 373 e-103
gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 373 e-103
gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 373 e-103
gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 373 e-103
gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 373 e-103
gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1 ... 373 e-103
gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 p... 373 e-103
gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precurso... 367 e-102
gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5 pr... 365 e-101
gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo s... 360 2e-99
gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precurs... 360 2e-99
gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1 p... 296 3e-80
gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2 iso... 292 4e-79
gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta pre... 291 9e-79
gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3 is... 285 5e-77
gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3 iso... 285 5e-77
gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2 is... 282 5e-76
gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo... 266 2e-71
gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens] 266 4e-71
gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens] 263 3e-70
gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens] 261 7e-70
gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens] 261 7e-70
>gi|38788135 gamma-aminobutyric acid A receptor, gamma 2 isoform 2
precursor [Homo sapiens]
Length = 467
Score = 968 bits (2503), Expect = 0.0
Identities = 467/467 (100%), Positives = 467/467 (100%)
Query: 1 MSSPNIWSTGSSVYSTPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPK 60
MSSPNIWSTGSSVYSTPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPK
Sbjct: 1 MSSPNIWSTGSSVYSTPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPK 60
Query: 61 VPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQT 120
VPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQT
Sbjct: 61 VPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQT 120
Query: 121 WYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLY 180
WYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLY
Sbjct: 121 WYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLY 180
Query: 181 TLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQF 240
TLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQF
Sbjct: 181 TLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQF 240
Query: 241 SFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDA 300
SFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDA
Sbjct: 241 SFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDA 300
Query: 301 VPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV 360
VPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV
Sbjct: 301 VPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV 360
Query: 361 SNRKPSKDKDKKKKNPAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCC 420
SNRKPSKDKDKKKKNPAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCC
Sbjct: 361 SNRKPSKDKDKKKKNPAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCC 420
Query: 421 FEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL 467
FEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL
Sbjct: 421 FEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL 467
>gi|38788155 gamma-aminobutyric acid A receptor, gamma 2 isoform 1
precursor [Homo sapiens]
Length = 475
Score = 961 bits (2484), Expect = 0.0
Identities = 467/475 (98%), Positives = 467/475 (98%), Gaps = 8/475 (1%)
Query: 1 MSSPNIWSTGSSVYSTPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPK 60
MSSPNIWSTGSSVYSTPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPK
Sbjct: 1 MSSPNIWSTGSSVYSTPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPK 60
Query: 61 VPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQT 120
VPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQT
Sbjct: 61 VPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQT 120
Query: 121 WYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLY 180
WYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLY
Sbjct: 121 WYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLY 180
Query: 181 TLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQF 240
TLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQF
Sbjct: 181 TLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQF 240
Query: 241 SFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDA 300
SFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDA
Sbjct: 241 SFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDA 300
Query: 301 VPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV 360
VPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV
Sbjct: 301 VPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV 360
Query: 361 SNRKPSKDKDKKKKNP--------APTIDIRPRSATIQMNNATHLQERDEEYGYECLDGK 412
SNRKPSKDKDKKKKNP APTIDIRPRSATIQMNNATHLQERDEEYGYECLDGK
Sbjct: 361 SNRKPSKDKDKKKKNPLLRMFSFKAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGK 420
Query: 413 DCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL 467
DCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL
Sbjct: 421 DCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL 475
>gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform 3
precursor [Homo sapiens]
Length = 515
Score = 939 bits (2428), Expect = 0.0
Identities = 466/515 (90%), Positives = 467/515 (90%), Gaps = 48/515 (9%)
Query: 1 MSSPNIWSTGSSVYSTPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPK 60
MSSPNIWSTGSSVYSTPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPK
Sbjct: 1 MSSPNIWSTGSSVYSTPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPK 60
Query: 61 VPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQT 120
VPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQT
Sbjct: 61 VPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQT 120
Query: 121 WYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLY 180
WYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLY
Sbjct: 121 WYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLY 180
Query: 181 TLRLTIDAECQLQLHNFPMDEHSCPLEFSSY----------------------------- 211
TLRLTIDAECQLQLHNFPMDEHSCPLEFSS+
Sbjct: 181 TLRLTIDAECQLQLHNFPMDEHSCPLEFSSWSRSIAQAGMCSGVISAHYSLRFWGSTDPP 240
Query: 212 -----------GYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYV 260
GYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYV
Sbjct: 241 TLASRVAGISDGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYV 300
Query: 261 VMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLST 320
VMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLST
Sbjct: 301 VMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLST 360
Query: 321 IARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNP---- 376
IARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNP
Sbjct: 361 IARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPLLRM 420
Query: 377 ----APTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHG 432
APTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHG
Sbjct: 421 FSFKAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHG 480
Query: 433 RIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL 467
RIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL
Sbjct: 481 RIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL 515
>gi|31742490 gamma-aminobutyric acid A receptor, gamma 1 precursor
[Homo sapiens]
Length = 465
Score = 717 bits (1850), Expect = 0.0
Identities = 346/444 (77%), Positives = 389/444 (87%), Gaps = 5/444 (1%)
Query: 27 ILLLLSLYPGFTSQKSDD-DYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDI 85
+ LLL+L+ G K+DD D ED NKTWVL PK+ EGD+T ILN+LL+GYDNKLRPDI
Sbjct: 24 VFLLLTLHLGNCVDKADDEDDEDLTVNKTWVLAPKIHEGDITQILNSLLQGYDNKLRPDI 83
Query: 86 GVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKI 145
GV+PT+I TD+YVNSIGPV+ INMEYTIDI FAQTW+D RLKFNST+KVL LNSNMVGKI
Sbjct: 84 GVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLKFNSTMKVLMLNSNMVGKI 143
Query: 146 WIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCP 205
WIPDTFFRNS+K+DAHWITTPNR+LRIWNDGRVLYTLRLTI+AEC LQLHNFPMDEHSCP
Sbjct: 144 WIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTINAECYLQLHNFPMDEHSCP 203
Query: 206 LEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVY 265
LEFSSYGYP+ EI Y+WK+ SVEV D + WRLYQF+FVGLRN+TE+ T SGDYV+M+++
Sbjct: 204 LEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLRNSTEITHTISGDYVIMTIF 263
Query: 266 FDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKS 325
FDLSRRMGYFTIQTYIPC L VVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKS
Sbjct: 264 FDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKS 323
Query: 326 LPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRK-PSKDKDKKKKNPAP-TIDIR 383
LPKVSYVTAMDLFVSVCFIFVF+AL+EYGTLHYF SN+K + KD+K KN A T +
Sbjct: 324 LPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSNQKGKTATKDRKLKNKASMTPGLH 383
Query: 384 PRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDS 443
P S I MNN + QE ++YGY+CL+GKDCASFFCCFEDCRTG+WR GRIHIRIAK+DS
Sbjct: 384 PGSTLIPMNNISVPQE--DDYGYQCLEGKDCASFFCCFEDCRTGSWREGRIHIRIAKIDS 441
Query: 444 YARIFFPTAFCLFNLVYWVSYLYL 467
Y+RIFFPTAF LFNLVYWV YLYL
Sbjct: 442 YSRIFFPTAFALFNLVYWVGYLYL 465
>gi|110347416 gamma-aminobutyric acid (GABA) A receptor, gamma 3
[Homo sapiens]
Length = 467
Score = 656 bits (1692), Expect = 0.0
Identities = 314/463 (67%), Positives = 382/463 (82%), Gaps = 22/463 (4%)
Query: 27 ILLLLSLYPGFTSQK---SDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRP 83
+LLLL L+ G ++ +D+YED +SN+ WVL PK + DVT+ILN LL YD KLRP
Sbjct: 5 LLLLLCLFSGLHARSRKVEEDEYEDSSSNQKWVLAPKSQDTDVTLILNKLLREYDKKLRP 64
Query: 84 DIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVG 143
DIG+KPT+I D+YVNSIGPV++INMEY IDIFFAQTW D RL+FNST+K+L LNSNMVG
Sbjct: 65 DIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRFNSTMKILTLNSNMVG 124
Query: 144 KIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHS 203
IWIPDT FRNSK A+AHWITTPN++LRIWNDG++LYTLRLTI+AECQLQLHNFPMDEHS
Sbjct: 125 LIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPMDEHS 184
Query: 204 CPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMS 263
CPL FSSYGYP+EE++Y+W+++SVE D +SWRLYQF F+GLRNTTE+V T++GDYVVM+
Sbjct: 185 CPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDYVVMT 244
Query: 264 VYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIAR 323
+YF+LSRRMGYFTIQTYIPC L VVLSWVSFWI KDA PART+LGITTVLTMTTLSTIAR
Sbjct: 245 IYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTIAR 304
Query: 324 KSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDK--------DKKKKN 375
KSLP+VSYVTAMDLFV+VCF+FVF+AL+EY TL+Y+ S RKP+ K D +
Sbjct: 305 KSLPRVSYVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTTTKKTTSLLHPDSSRWI 364
Query: 376 P------APT----IDIR-PRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDC 424
P AP+ +D+R P +A I +NN+ + QE ++ YECLDGKDC SFFCC+E+C
Sbjct: 365 PERISLQAPSNYSLLDMRPPPTAMITLNNSVYWQEFEDTCVYECLDGKDCQSFFCCYEEC 424
Query: 425 RTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL 467
++G+WR GRIHI I ++DSY+R+FFPT+F LFNLVYWV YLYL
Sbjct: 425 KSGSWRKGRIHIDILELDSYSRVFFPTSFLLFNLVYWVGYLYL 467
>gi|52426761 gamma-aminobutyric acid (GABA) A receptor, epsilon
precursor [Homo sapiens]
Length = 506
Score = 409 bits (1050), Expect = e-114
Identities = 193/445 (43%), Positives = 285/445 (64%), Gaps = 42/445 (9%)
Query: 60 KVPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQ 119
K+PE + ILN +L YD+KLRP IG KPT++ ++ VNS+GP++ ++MEYTIDI F+Q
Sbjct: 67 KLPEA--SRILNTILSNYDHKLRPGIGEKPTVVTVEISVNSLGPLSILDMEYTIDIIFSQ 124
Query: 120 TWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVL 179
TWYD RL +N T + L LN N+V ++WIPDTFFRNSK+ H IT PN+M+RI+ DG+VL
Sbjct: 125 TWYDERLCYNDTFESLVLNGNVVSQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVL 184
Query: 180 YTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQ 239
YT+R+TIDA C L + FPMD HSCPL FSS+ YP E++Y+W+ +E+ + SW+L+Q
Sbjct: 185 YTIRMTIDAGCSLHMLRFPMDSHSCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQ 244
Query: 240 FSFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKD 299
F F G+ N TE++ T GD++VM+++F++SRR GY Q Y+P ++ +LSWVSFWI +
Sbjct: 245 FDFTGVSNKTEIITTPVGDFMVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTE 304
Query: 300 AVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYF 359
+ PARTSLGIT+VLTMTTL T +RK+ P+VSY+TA+D ++++CF+F F AL+E+ L++
Sbjct: 305 SAPARTSLGITSVLTMTTLGTFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFL 364
Query: 360 VSNRKPSKDKDKKKKNPAPTIDIRPRSATIQMNNATHLQERD----EEYGYECLDGKDCA 415
+ N+ + K + P I+ R + T + A Q ++ + E DG++
Sbjct: 365 IYNQTKAHASPKLRH---PRINSRAHARTRARSRACARQHQEAFVCQIVTTEGSDGEERP 421
Query: 416 S---------------------------------FFCCFEDCRTGAWRHGRIHIRIAKMD 442
S +FC DC W+ GR+ I + ++D
Sbjct: 422 SCSAQQPPSPGSPEGPRSLCSKLACCEWCKRFKKYFCMVPDCEGSTWQQGRLCIHVYRLD 481
Query: 443 SYARIFFPTAFCLFNLVYWVSYLYL 467
+Y+R+ FP F FN++YW+ L L
Sbjct: 482 NYSRVVFPVTFFFFNVLYWLVCLNL 506
>gi|157389018 gamma-aminobutyric acid A receptor, alpha 6 precursor
[Homo sapiens]
Length = 453
Score = 394 bits (1012), Expect = e-110
Identities = 206/413 (49%), Positives = 274/413 (66%), Gaps = 14/413 (3%)
Query: 65 DVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDR 124
+V+ IL+NLLEGYDN+LRP G T + TD+YV S GPV+ + MEYT+D+FF QTW D
Sbjct: 31 NVSRILDNLLEGYDNRLRPGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDE 90
Query: 125 RLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRL 184
RLKF ++L LN+ MV KIW PDTFFRN KK+ AH +TTPN++ RI +G +LYT+RL
Sbjct: 91 RLKFGGPTEILSLNNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRL 150
Query: 185 TIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRS---SVEVGDTRSWRLYQFS 241
TI+A+C ++L NFPMD H+CPL+F SY YP+ EI+Y WK+ SVEV + S L Q+
Sbjct: 151 TINADCPMRLVNFPMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESS-SLLQYD 209
Query: 242 FVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAV 301
+G ++E +K+ +G+YV+M+VYF L R+MGYF IQ Y PC + V+LS VSFWINK++V
Sbjct: 210 LIGQTVSSETIKSNTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESV 269
Query: 302 PARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVS 361
PART GITTVLTMTTLS AR SLPKVSY TAMD F++VCF FVFSAL+E+ ++YF +
Sbjct: 270 PARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF-T 328
Query: 362 NRKPSKDKDKKKKNPAPTIDI----RPRSATIQM--NNATHLQERDEEYGYECLDGKDCA 415
N + K K K + PT+ I P A I + ++ HL++R + +
Sbjct: 329 NLQTQKAKRKAQFAAPPTVTISKATEPLEAEIVLHPDSKYHLKKRITSLSLPIVSSSEAN 388
Query: 416 SFFCCFEDCRTGAWRHGRIHIRI---AKMDSYARIFFPTAFCLFNLVYWVSYL 465
++ + +K+D Y+RI FP AF FNLVYWV YL
Sbjct: 389 KVLTRAPILQSTPVTPPPLSPAFGGTSKIDQYSRILFPVAFAGFNLVYWVVYL 441
>gi|4557603 gamma-aminobutyric acid A receptor, alpha 3 precursor
[Homo sapiens]
Length = 492
Score = 384 bits (987), Expect = e-107
Identities = 207/467 (44%), Positives = 290/467 (62%), Gaps = 31/467 (6%)
Query: 27 ILLLLSLYPGFTSQKSDDDYE--DYASNKTWVLTPK----VPEGDV------TVILNNLL 74
IL L+++ PG T Q E D+ L+PK +P+ T IL+ LL
Sbjct: 16 ILFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDSTDNITIFTRILDRLL 75
Query: 75 EGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKV 134
+GYDN+LRP +G T + TD+YV S GPV+ +MEYTID+FF QTW+D RLKF+ +K+
Sbjct: 76 DGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLKFDGPMKI 135
Query: 135 LRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQL 194
L LN+ + KIW PDTFF N KK+ AH +TTPN++LR+ ++G +LYT+RLTI AEC + L
Sbjct: 136 LPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTIHAECPMHL 195
Query: 195 HNFPMDEHSCPLEFSSYGYPREEIVYQW---KRSSVEVGDTRSWRLYQFSFVGLRNTTEV 251
+FPMD H+CPL+F SY Y E+VY W K SVEV S RL Q+ +G TE+
Sbjct: 196 EDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGS-RLNQYDLLGHVVGTEI 254
Query: 252 VKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITT 311
+++++G+YVVM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPART G+TT
Sbjct: 255 IRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTT 314
Query: 312 VLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV------SNRKP 365
VLTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF +K
Sbjct: 315 VLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRSWAWEGKKV 374
Query: 366 SKDKDKKKKNPAPTIDIRPRSATIQMNNATH--LQERDEEYGYECLDGKDCASFFCCFED 423
+ + KKK PA + S T + T+ +D E+ AS
Sbjct: 375 PEALEMKKKTPA--APAKKTSTTFNIVGTTYPINLAKDTEFSTISKGAAPSASSTPTIIA 432
Query: 424 CRTGAW-----RHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 465
+ + + ++K+D +RI FP F +FNLVYW +Y+
Sbjct: 433 SPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYV 479
>gi|189083734 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 373 bits (958), Expect = e-103
Identities = 211/468 (45%), Positives = 284/468 (60%), Gaps = 46/468 (9%)
Query: 16 TPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLE 75
+P S + WILLL +L Q S +D + T V T IL+ LL+
Sbjct: 4 SPGLSDCLWAWILLLSTLTGRSYGQPS---LQDELKDNTTVFTR---------ILDRLLD 51
Query: 76 GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVL 135
GYDN+LRP +G + T + TD++V S GPV+ +MEYTID+FF Q+W D RLKF + VL
Sbjct: 52 GYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVL 111
Query: 136 RLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLH 195
RLN+ M KIW PDTFF N KK+ AH +T PN++LRI DG +LYT+RLT+ AEC + L
Sbjct: 112 RLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLE 171
Query: 196 NFPMDEHSCPLEFSSYGYPREEIVYQWKRS---SVEVGDTRSWRLYQFSFVGLRNTTEVV 252
+FPMD H+CPL+F SY Y R E+VY+W R SV V + S RL Q+ +G + +V
Sbjct: 172 DFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLLGQTVDSGIV 230
Query: 253 KTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTV 312
++++G+YVVM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPART G+TTV
Sbjct: 231 QSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTV 290
Query: 313 LTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYF-----------VS 361
LTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF V
Sbjct: 291 LTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVV 350
Query: 362 NRKPSKDKD---KKKKNPAPT-IDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASF 417
KP K KD KK APT P A AT + ++ K+
Sbjct: 351 PEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKS-------ATIEPKEVKP- 402
Query: 418 FCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 465
T + ++K+D +RI FP F +FNLVYW +YL
Sbjct: 403 -------ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
>gi|189083732 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 373 bits (958), Expect = e-103
Identities = 211/468 (45%), Positives = 284/468 (60%), Gaps = 46/468 (9%)
Query: 16 TPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLE 75
+P S + WILLL +L Q S +D + T V T IL+ LL+
Sbjct: 4 SPGLSDCLWAWILLLSTLTGRSYGQPS---LQDELKDNTTVFTR---------ILDRLLD 51
Query: 76 GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVL 135
GYDN+LRP +G + T + TD++V S GPV+ +MEYTID+FF Q+W D RLKF + VL
Sbjct: 52 GYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVL 111
Query: 136 RLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLH 195
RLN+ M KIW PDTFF N KK+ AH +T PN++LRI DG +LYT+RLT+ AEC + L
Sbjct: 112 RLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLE 171
Query: 196 NFPMDEHSCPLEFSSYGYPREEIVYQWKRS---SVEVGDTRSWRLYQFSFVGLRNTTEVV 252
+FPMD H+CPL+F SY Y R E+VY+W R SV V + S RL Q+ +G + +V
Sbjct: 172 DFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLLGQTVDSGIV 230
Query: 253 KTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTV 312
++++G+YVVM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPART G+TTV
Sbjct: 231 QSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTV 290
Query: 313 LTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYF-----------VS 361
LTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF V
Sbjct: 291 LTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVV 350
Query: 362 NRKPSKDKD---KKKKNPAPT-IDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASF 417
KP K KD KK APT P A AT + ++ K+
Sbjct: 351 PEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKS-------ATIEPKEVKP- 402
Query: 418 FCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 465
T + ++K+D +RI FP F +FNLVYW +YL
Sbjct: 403 -------ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
>gi|189083730 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 373 bits (958), Expect = e-103
Identities = 211/468 (45%), Positives = 284/468 (60%), Gaps = 46/468 (9%)
Query: 16 TPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLE 75
+P S + WILLL +L Q S +D + T V T IL+ LL+
Sbjct: 4 SPGLSDCLWAWILLLSTLTGRSYGQPS---LQDELKDNTTVFTR---------ILDRLLD 51
Query: 76 GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVL 135
GYDN+LRP +G + T + TD++V S GPV+ +MEYTID+FF Q+W D RLKF + VL
Sbjct: 52 GYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVL 111
Query: 136 RLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLH 195
RLN+ M KIW PDTFF N KK+ AH +T PN++LRI DG +LYT+RLT+ AEC + L
Sbjct: 112 RLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLE 171
Query: 196 NFPMDEHSCPLEFSSYGYPREEIVYQWKRS---SVEVGDTRSWRLYQFSFVGLRNTTEVV 252
+FPMD H+CPL+F SY Y R E+VY+W R SV V + S RL Q+ +G + +V
Sbjct: 172 DFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLLGQTVDSGIV 230
Query: 253 KTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTV 312
++++G+YVVM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPART G+TTV
Sbjct: 231 QSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTV 290
Query: 313 LTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYF-----------VS 361
LTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF V
Sbjct: 291 LTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVV 350
Query: 362 NRKPSKDKD---KKKKNPAPT-IDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASF 417
KP K KD KK APT P A AT + ++ K+
Sbjct: 351 PEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKS-------ATIEPKEVKP- 402
Query: 418 FCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 465
T + ++K+D +RI FP F +FNLVYW +YL
Sbjct: 403 -------ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
>gi|189083728 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 373 bits (958), Expect = e-103
Identities = 211/468 (45%), Positives = 284/468 (60%), Gaps = 46/468 (9%)
Query: 16 TPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLE 75
+P S + WILLL +L Q S +D + T V T IL+ LL+
Sbjct: 4 SPGLSDCLWAWILLLSTLTGRSYGQPS---LQDELKDNTTVFTR---------ILDRLLD 51
Query: 76 GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVL 135
GYDN+LRP +G + T + TD++V S GPV+ +MEYTID+FF Q+W D RLKF + VL
Sbjct: 52 GYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVL 111
Query: 136 RLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLH 195
RLN+ M KIW PDTFF N KK+ AH +T PN++LRI DG +LYT+RLT+ AEC + L
Sbjct: 112 RLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLE 171
Query: 196 NFPMDEHSCPLEFSSYGYPREEIVYQWKRS---SVEVGDTRSWRLYQFSFVGLRNTTEVV 252
+FPMD H+CPL+F SY Y R E+VY+W R SV V + S RL Q+ +G + +V
Sbjct: 172 DFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLLGQTVDSGIV 230
Query: 253 KTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTV 312
++++G+YVVM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPART G+TTV
Sbjct: 231 QSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTV 290
Query: 313 LTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYF-----------VS 361
LTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF V
Sbjct: 291 LTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVV 350
Query: 362 NRKPSKDKD---KKKKNPAPT-IDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASF 417
KP K KD KK APT P A AT + ++ K+
Sbjct: 351 PEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKS-------ATIEPKEVKP- 402
Query: 418 FCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 465
T + ++K+D +RI FP F +FNLVYW +YL
Sbjct: 403 -------ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
>gi|189083726 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 373 bits (958), Expect = e-103
Identities = 211/468 (45%), Positives = 284/468 (60%), Gaps = 46/468 (9%)
Query: 16 TPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLE 75
+P S + WILLL +L Q S +D + T V T IL+ LL+
Sbjct: 4 SPGLSDCLWAWILLLSTLTGRSYGQPS---LQDELKDNTTVFTR---------ILDRLLD 51
Query: 76 GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVL 135
GYDN+LRP +G + T + TD++V S GPV+ +MEYTID+FF Q+W D RLKF + VL
Sbjct: 52 GYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVL 111
Query: 136 RLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLH 195
RLN+ M KIW PDTFF N KK+ AH +T PN++LRI DG +LYT+RLT+ AEC + L
Sbjct: 112 RLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLE 171
Query: 196 NFPMDEHSCPLEFSSYGYPREEIVYQWKRS---SVEVGDTRSWRLYQFSFVGLRNTTEVV 252
+FPMD H+CPL+F SY Y R E+VY+W R SV V + S RL Q+ +G + +V
Sbjct: 172 DFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLLGQTVDSGIV 230
Query: 253 KTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTV 312
++++G+YVVM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPART G+TTV
Sbjct: 231 QSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTV 290
Query: 313 LTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYF-----------VS 361
LTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF V
Sbjct: 291 LTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVV 350
Query: 362 NRKPSKDKD---KKKKNPAPT-IDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASF 417
KP K KD KK APT P A AT + ++ K+
Sbjct: 351 PEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKS-------ATIEPKEVKP- 402
Query: 418 FCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 465
T + ++K+D +RI FP F +FNLVYW +YL
Sbjct: 403 -------ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
>gi|189083724 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 373 bits (958), Expect = e-103
Identities = 211/468 (45%), Positives = 284/468 (60%), Gaps = 46/468 (9%)
Query: 16 TPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLE 75
+P S + WILLL +L Q S +D + T V T IL+ LL+
Sbjct: 4 SPGLSDCLWAWILLLSTLTGRSYGQPS---LQDELKDNTTVFTR---------ILDRLLD 51
Query: 76 GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVL 135
GYDN+LRP +G + T + TD++V S GPV+ +MEYTID+FF Q+W D RLKF + VL
Sbjct: 52 GYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVL 111
Query: 136 RLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLH 195
RLN+ M KIW PDTFF N KK+ AH +T PN++LRI DG +LYT+RLT+ AEC + L
Sbjct: 112 RLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLE 171
Query: 196 NFPMDEHSCPLEFSSYGYPREEIVYQWKRS---SVEVGDTRSWRLYQFSFVGLRNTTEVV 252
+FPMD H+CPL+F SY Y R E+VY+W R SV V + S RL Q+ +G + +V
Sbjct: 172 DFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLLGQTVDSGIV 230
Query: 253 KTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTV 312
++++G+YVVM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPART G+TTV
Sbjct: 231 QSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTV 290
Query: 313 LTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYF-----------VS 361
LTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF V
Sbjct: 291 LTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVV 350
Query: 362 NRKPSKDKD---KKKKNPAPT-IDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASF 417
KP K KD KK APT P A AT + ++ K+
Sbjct: 351 PEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKS-------ATIEPKEVKP- 402
Query: 418 FCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 465
T + ++K+D +RI FP F +FNLVYW +YL
Sbjct: 403 -------ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
>gi|38327554 gamma-aminobutyric acid (GABA) A receptor, alpha 1
precursor [Homo sapiens]
Length = 456
Score = 373 bits (958), Expect = e-103
Identities = 211/468 (45%), Positives = 284/468 (60%), Gaps = 46/468 (9%)
Query: 16 TPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLE 75
+P S + WILLL +L Q S +D + T V T IL+ LL+
Sbjct: 4 SPGLSDCLWAWILLLSTLTGRSYGQPS---LQDELKDNTTVFTR---------ILDRLLD 51
Query: 76 GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVL 135
GYDN+LRP +G + T + TD++V S GPV+ +MEYTID+FF Q+W D RLKF + VL
Sbjct: 52 GYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVL 111
Query: 136 RLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLH 195
RLN+ M KIW PDTFF N KK+ AH +T PN++LRI DG +LYT+RLT+ AEC + L
Sbjct: 112 RLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLE 171
Query: 196 NFPMDEHSCPLEFSSYGYPREEIVYQWKRS---SVEVGDTRSWRLYQFSFVGLRNTTEVV 252
+FPMD H+CPL+F SY Y R E+VY+W R SV V + S RL Q+ +G + +V
Sbjct: 172 DFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGS-RLNQYDLLGQTVDSGIV 230
Query: 253 KTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTV 312
++++G+YVVM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPART G+TTV
Sbjct: 231 QSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTV 290
Query: 313 LTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYF-----------VS 361
LTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF V
Sbjct: 291 LTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVV 350
Query: 362 NRKPSKDKD---KKKKNPAPT-IDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASF 417
KP K KD KK APT P A AT + ++ K+
Sbjct: 351 PEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATIAKS-------ATIEPKEVKP- 402
Query: 418 FCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 465
T + ++K+D +RI FP F +FNLVYW +YL
Sbjct: 403 -------ETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL 443
>gi|34452723 gamma-aminobutyric acid A receptor, alpha 4 precursor
[Homo sapiens]
Length = 554
Score = 367 bits (943), Expect = e-102
Identities = 183/336 (54%), Positives = 242/336 (72%), Gaps = 10/336 (2%)
Query: 67 TVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRL 126
T IL++LL+GYDN+LRP G T + TD+YV S GPV+ + MEYT+D+FF QTW D+RL
Sbjct: 49 TRILDSLLDGYDNRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRL 108
Query: 127 KFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTI 186
K++ I++LRLN+ MV K+W PDTFFRN KK+ +H +T PN++ RI +G +LYT+RLTI
Sbjct: 109 KYDGPIEILRLNNMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTI 168
Query: 187 DAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKR---SSVEVGDTRSWRLYQFSFV 243
AEC ++L +FPMD H+CPL+F SY YP+ E++Y W + SVEV S L Q+ +
Sbjct: 169 SAECPMRLVDFPMDGHACPLKFGSYAYPKSEMIYTWTKGPEKSVEV-PKESSSLVQYDLI 227
Query: 244 GLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPA 303
G ++E +K+ +G+Y+VM+VYF L R+MGYF IQTYIPC + V+LS VSFWINK++VPA
Sbjct: 228 GQTVSSETIKSITGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPA 287
Query: 304 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNR 363
RT GITTVLTMTTLS AR SLPKVSY TAMD F++VCF FVFSAL+E+ ++YF +N
Sbjct: 288 RTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF-TNI 346
Query: 364 KPSKDKDKKKKNP-----APTIDIRPRSATIQMNNA 394
+ K K K K P AP + A +Q NA
Sbjct: 347 QMEKAKRKTSKPPQEVPAAPVQREKHPEAPLQNTNA 382
Score = 42.0 bits (97), Expect = 0.001
Identities = 17/27 (62%), Positives = 20/27 (74%)
Query: 439 AKMDSYARIFFPTAFCLFNLVYWVSYL 465
+K+D YARI FP F FN+VYWV YL
Sbjct: 516 SKIDKYARILFPVTFGAFNMVYWVVYL 542
>gi|4503861 gamma-aminobutyric acid (GABA) A receptor, alpha 5
precursor [Homo sapiens]
Length = 462
Score = 365 bits (937), Expect = e-101
Identities = 189/408 (46%), Positives = 263/408 (64%), Gaps = 17/408 (4%)
Query: 67 TVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRL 126
T IL+ LL+GYDN+LRP +G + T + TD+YV S GPV+ MEYTID+FF Q+W D RL
Sbjct: 50 TRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERL 109
Query: 127 KFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTI 186
+F ++ L LN+ + KIW PDTFF N KK+ AH +TTPN++LR+ +DG +LYT+RLTI
Sbjct: 110 RFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTI 169
Query: 187 DAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQW---KRSSVEVGDTRSWRLYQFSFV 243
AEC +QL +FPMD H+CPL+F SY YP E+VY W SV V + S RL Q+ +
Sbjct: 170 SAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGS-RLNQYHLM 228
Query: 244 GLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPA 303
G TE + T++G+Y +M+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPA
Sbjct: 229 GQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 288
Query: 304 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV--- 360
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF
Sbjct: 289 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 348
Query: 361 ---SNRKPSKDKDKKKKNPAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASF 417
+K + KKK T +M++ ++ + G + S
Sbjct: 349 WAWDGKKALEAAKIKKKREVILNKSTNAFTTGKMSHPPNIPKEQTPAG-----TSNTTSV 403
Query: 418 FCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYL 465
+ +T + + + I+K+D +RI FP F FNLVYW +YL
Sbjct: 404 SVKPSEEKTSESK--KTYNSISKIDKMSRIVFPVLFGTFNLVYWATYL 449
>gi|167000817 gamma-aminobutyric acid A receptor, alpha 2 [Homo
sapiens]
Length = 451
Score = 360 bits (923), Expect = 2e-99
Identities = 191/422 (45%), Positives = 260/422 (61%), Gaps = 46/422 (10%)
Query: 67 TVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRL 126
T IL+ LL+GYDN+LRP +G T + T++YV S GPV+ +MEYTID+FF Q W D RL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
Query: 127 KFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTI 186
KF + +LRLN+ M KIW PDTFF N KK+ AH +T PN++LRI +DG +LYT+RLT+
Sbjct: 103 KFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTV 162
Query: 187 DAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQW---KRSSVEVGDTRSWRLYQFSFV 243
AEC + L +FPMD HSCPL+F SY Y E+ Y W SV+V S RL Q+ +
Sbjct: 163 QAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGS-RLNQYDLL 221
Query: 244 GLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPA 303
G E +K+++G+Y VM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPA
Sbjct: 222 GQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 281
Query: 304 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV--- 360
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF
Sbjct: 282 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 341
Query: 361 ---SNRKPSKDKDKKK--------------KNPAPTIDIRPRSATIQMNNATHLQERDEE 403
+ DK K+K N AP + P +TI + T E +++
Sbjct: 342 WAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLSKDPVLSTISKSATT--PEPNKK 399
Query: 404 YGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVS 463
+ + K + ++K+D +RI FP F FNLVYW +
Sbjct: 400 PENKPAEAK--------------------KTFNSVSKIDRMSRIVFPVLFGTFNLVYWAT 439
Query: 464 YL 465
YL
Sbjct: 440 YL 441
>gi|167000751 gamma-aminobutyric acid A receptor, alpha 2 precursor
[Homo sapiens]
Length = 451
Score = 360 bits (923), Expect = 2e-99
Identities = 191/422 (45%), Positives = 260/422 (61%), Gaps = 46/422 (10%)
Query: 67 TVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRL 126
T IL+ LL+GYDN+LRP +G T + T++YV S GPV+ +MEYTID+FF Q W D RL
Sbjct: 43 TRILDRLLDGYDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERL 102
Query: 127 KFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTI 186
KF + +LRLN+ M KIW PDTFF N KK+ AH +T PN++LRI +DG +LYT+RLT+
Sbjct: 103 KFKGPMNILRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTV 162
Query: 187 DAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQW---KRSSVEVGDTRSWRLYQFSFV 243
AEC + L +FPMD HSCPL+F SY Y E+ Y W SV+V S RL Q+ +
Sbjct: 163 QAECPMHLEDFPMDAHSCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGS-RLNQYDLL 221
Query: 244 GLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPA 303
G E +K+++G+Y VM+ +F L R++GYF IQTY+PC + V+LS VSFW+N+++VPA
Sbjct: 222 GQSIGKETIKSSTGEYTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPA 281
Query: 304 RTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFV--- 360
RT G+TTVLTMTTLS AR SLPKV+Y TAMD F++VC+ FVFSAL+E+ T++YF
Sbjct: 282 RTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRG 341
Query: 361 ---SNRKPSKDKDKKK--------------KNPAPTIDIRPRSATIQMNNATHLQERDEE 403
+ DK K+K N AP + P +TI + T E +++
Sbjct: 342 WAWDGKSVVNDKKKEKASVMIQNNAYAVAVANYAPNLSKDPVLSTISKSATT--PEPNKK 399
Query: 404 YGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVS 463
+ + K + ++K+D +RI FP F FNLVYW +
Sbjct: 400 PENKPAEAK--------------------KTFNSVSKIDRMSRIVFPVLFGTFNLVYWAT 439
Query: 464 YL 465
YL
Sbjct: 440 YL 441
>gi|194097327 gamma-aminobutyric acid (GABA) A receptor, beta 1
precursor [Homo sapiens]
Length = 474
Score = 296 bits (758), Expect = 3e-80
Identities = 163/434 (37%), Positives = 243/434 (55%), Gaps = 37/434 (8%)
Query: 70 LNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFN 129
++ LL+GYD +LRPD G P + + V SI V+ +NM+YT+ ++F Q+W D+RL ++
Sbjct: 41 VDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYS 100
Query: 130 STIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAE 189
L L++ + ++W+PDT+F N KK+ H +T NRM+R+ DG VLY LR+T A
Sbjct: 101 GIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 160
Query: 190 CQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTT 249
C + L +P+DE +C LE SYGY ++I + W V L QFS V + +
Sbjct: 161 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVS 220
Query: 250 EVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGI 309
+ V+ T+G Y +S+ F L R +GYF +QTY+P TLI +LSWVSFWIN DA AR +LGI
Sbjct: 221 KKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGI 280
Query: 310 TTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSK-- 367
TTVLTMTT+ST R++LPK+ YV A+D+++ CF+FVF AL+EY ++Y + P K
Sbjct: 281 TTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKG 340
Query: 368 -DKDKKKKNPAPTIDIRPRSATIQMN-NATHLQERDEEYGYECLDG-KDCASFFCCFEDC 424
K + N +++ N + L+ R+E G E L D + ++
Sbjct: 341 ASKQDQSANEKNKLEMNKVQVDAHGNILLSTLEIRNETSGSEVLTSVSDPKATMYSYDSA 400
Query: 425 -------------------RTGAWRHGRIHIRIAKM-------------DSYARIFFPTA 452
R G GRI R +++ D ++R+FFP
Sbjct: 401 SIQYRKPLSSREAYGRALDRHGVPSKGRIRRRASQLKVKIPDLTDVNSIDKWSRMFFPIT 460
Query: 453 FCLFNLVYWVSYLY 466
F LFN+VYW+ Y++
Sbjct: 461 FSLFNVVYWLYYVH 474
>gi|4503865 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 2 [Homo sapiens]
Length = 474
Score = 292 bits (748), Expect = 4e-79
Identities = 159/434 (36%), Positives = 239/434 (55%), Gaps = 38/434 (8%)
Query: 70 LNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFN 129
++ LL+GYD +LRPD G P + ++ + SI V+ +NM+YT+ ++F Q W D+RL +N
Sbjct: 40 VDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYN 99
Query: 130 STIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAE 189
L L++ + ++W+PDT+F N KK+ H +T NRM+R+ DG VLY LR+T A
Sbjct: 100 VIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 159
Query: 190 CQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTT 249
C + L +P+DE +C LE SYGY ++I + W+ V L QFS V + T
Sbjct: 160 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLIT 219
Query: 250 EVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGI 309
+ V ++G Y +S+ F L R +GYF +QTY+P LI +LSWVSFWIN DA AR +LGI
Sbjct: 220 KKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 279
Query: 310 TTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDK 369
TTVLTMTT++T R++LPK+ YV A+D+++ CF+FVF AL+EY ++Y R P + K
Sbjct: 280 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQK 339
Query: 370 DKKKK-----NPAPTIDIRPRS-------ATIQMNNATHLQE--------RDEEYGYECL 409
+K N +D+ +T+++ N E R Y+
Sbjct: 340 KAAEKAASANNEKMRLDVNKMDPHENILLSTLEIKNEMATSEAVMGLGDPRSTMLAYDAS 399
Query: 410 DGKDCASFFCCFEDCRTGAWRH-----GRIHIRIAKM-------------DSYARIFFPT 451
+ + R RH R+ R +++ D ++RIFFP
Sbjct: 400 SIQYRKAGLPRHSFGRNALERHVAQKKSRLRRRASQLKITIPDLTDVNAIDRWSRIFFPV 459
Query: 452 AFCLFNLVYWVSYL 465
F FN+VYW+ Y+
Sbjct: 460 VFSFFNIVYWLYYV 473
>gi|34734071 gamma-aminobutyric acid (GABA) A receptor, delta
precursor [Homo sapiens]
Length = 452
Score = 291 bits (745), Expect = 9e-79
Identities = 160/408 (39%), Positives = 230/408 (56%), Gaps = 14/408 (3%)
Query: 70 LNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFN 129
L+ L+ GY RP IG P + + V SI ++ NMEYT+ +F Q+W D RL +N
Sbjct: 44 LDGLIAGYARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSYN 103
Query: 130 STIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAE 189
T + L L+S V K+W+PDTF N+K A H +T N+++R+ DG +LY++R+T
Sbjct: 104 HTNETLGLDSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVA 163
Query: 190 CQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTT 249
C + L +PMDE C L+ SYGY E+IVY W S + +L QF+ R TT
Sbjct: 164 CDMDLAKYPMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFTT 223
Query: 250 EVVK-TTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLG 308
E++ ++G + +S++F L R G + IQ+Y+P L+V +SWVSFWI++ AVPAR SLG
Sbjct: 224 ELMNFKSAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLG 283
Query: 309 ITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKD 368
ITTVLTMTTL AR SLP+ S + A+D++ +C++FVF+ALVEY H+ RK K
Sbjct: 284 ITTVLTMTTLMVSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYRKKQKA 343
Query: 369 KDKKKKNPAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFC----CFEDC 424
K K + P +D+R ++ A QE + G S+ E
Sbjct: 344 KVKVSR-PRAEMDVRNAIVLFSLSAAGVTQELAISRRQRRVPGNLMGSYRSVGVETGETK 402
Query: 425 RTGAWR---HGRIHIRIAKMDS-----YARIFFPTAFCLFNLVYWVSY 464
+ GA R G I R+ +D+ YAR FP AF N++YW +Y
Sbjct: 403 KEGAARSGGQGGIRARLRPIDADTIDIYARAVFPAAFAAVNVIYWAAY 450
>gi|12548788 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 2 precursor [Homo sapiens]
Length = 473
Score = 285 bits (730), Expect = 5e-77
Identities = 160/433 (36%), Positives = 240/433 (55%), Gaps = 38/433 (8%)
Query: 70 LNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFN 129
++ LL+GYD +LRPD G P + ++ + SI V+ +NM+YT+ ++F Q W D+RL ++
Sbjct: 41 VDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYS 100
Query: 130 STIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAE 189
L L++ + ++W+PDT+F N KK+ H +T NRM+R+ DG VLY LR+T A
Sbjct: 101 GIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 160
Query: 190 CQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTT 249
C + L +P+DE +C LE SYGY ++I + W+ V L QFS V R +
Sbjct: 161 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVS 220
Query: 250 EVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGI 309
V +G Y +S+ F L R +GYF +QTY+P LI +LSWVSFWIN DA AR +LGI
Sbjct: 221 RNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 280
Query: 310 TTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDK 369
TTVLTMTT++T R++LPK+ YV A+D+++ CF+FVF AL+EY ++Y R P + K
Sbjct: 281 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQK 340
Query: 370 DKKKKNPAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGK----DCASFFCCFEDC- 424
+K D R +S + +++ ++ E E + D + F++
Sbjct: 341 KLAEKTAKAKND-RSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSG 399
Query: 425 ---------RTGAWR--------HGRIHIR---------------IAKMDSYARIFFPTA 452
R G R H + H+R + +D ++RI FP
Sbjct: 400 IQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFT 459
Query: 453 FCLFNLVYWVSYL 465
F LFNLVYW+ Y+
Sbjct: 460 FSLFNLVYWLYYV 472
>gi|4503867 gamma-aminobutyric acid (GABA) A receptor, beta 3
isoform 1 precursor [Homo sapiens]
Length = 473
Score = 285 bits (730), Expect = 5e-77
Identities = 160/433 (36%), Positives = 240/433 (55%), Gaps = 38/433 (8%)
Query: 70 LNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFN 129
++ LL+GYD +LRPD G P + ++ + SI V+ +NM+YT+ ++F Q W D+RL ++
Sbjct: 41 VDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYS 100
Query: 130 STIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAE 189
L L++ + ++W+PDT+F N KK+ H +T NRM+R+ DG VLY LR+T A
Sbjct: 101 GIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 160
Query: 190 CQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTT 249
C + L +P+DE +C LE SYGY ++I + W+ V L QFS V R +
Sbjct: 161 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVS 220
Query: 250 EVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGI 309
V +G Y +S+ F L R +GYF +QTY+P LI +LSWVSFWIN DA AR +LGI
Sbjct: 221 RNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 280
Query: 310 TTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDK 369
TTVLTMTT++T R++LPK+ YV A+D+++ CF+FVF AL+EY ++Y R P + K
Sbjct: 281 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQK 340
Query: 370 DKKKKNPAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGK----DCASFFCCFEDC- 424
+K D R +S + +++ ++ E E + D + F++
Sbjct: 341 KLAEKTAKAKND-RSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSG 399
Query: 425 ---------RTGAWR--------HGRIHIR---------------IAKMDSYARIFFPTA 452
R G R H + H+R + +D ++RI FP
Sbjct: 400 IQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFT 459
Query: 453 FCLFNLVYWVSYL 465
F LFNLVYW+ Y+
Sbjct: 460 FSLFNLVYWLYYV 472
>gi|12548785 gamma-aminobutyric acid (GABA) A receptor, beta 2
isoform 1 [Homo sapiens]
Length = 512
Score = 282 bits (721), Expect = 5e-76
Identities = 134/305 (43%), Positives = 196/305 (64%)
Query: 70 LNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFN 129
++ LL+GYD +LRPD G P + ++ + SI V+ +NM+YT+ ++F Q W D+RL +N
Sbjct: 40 VDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLSYN 99
Query: 130 STIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAE 189
L L++ + ++W+PDT+F N KK+ H +T NRM+R+ DG VLY LR+T A
Sbjct: 100 VIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 159
Query: 190 CQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTT 249
C + L +P+DE +C LE SYGY ++I + W+ V L QFS V + T
Sbjct: 160 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLIT 219
Query: 250 EVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGI 309
+ V ++G Y +S+ F L R +GYF +QTY+P LI +LSWVSFWIN DA AR +LGI
Sbjct: 220 KKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 279
Query: 310 TTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDK 369
TTVLTMTT++T R++LPK+ YV A+D+++ CF+FVF AL+EY ++Y R P + K
Sbjct: 280 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYIFFGRGPQRQK 339
Query: 370 DKKKK 374
+K
Sbjct: 340 KAAEK 344
Score = 37.4 bits (85), Expect = 0.029
Identities = 13/25 (52%), Positives = 19/25 (76%)
Query: 441 MDSYARIFFPTAFCLFNLVYWVSYL 465
+D ++RIFFP F FN+VYW+ Y+
Sbjct: 487 IDRWSRIFFPVVFSFFNIVYWLYYV 511
>gi|225903367 glycine receptor, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 457
Score = 266 bits (681), Expect = 2e-71
Identities = 153/404 (37%), Positives = 230/404 (56%), Gaps = 23/404 (5%)
Query: 76 GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNS-TIKV 134
GYD ++RP+ P + ++++NS G + M+Y ++IF Q W D RL +N
Sbjct: 51 GYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPDDS 110
Query: 135 LRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQL 194
L L+ +M+ IW PD FF N K A H ITT N++LRI +G VLY++R+T+ C + L
Sbjct: 111 LDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDL 170
Query: 195 HNFPMDEHSCPLEFSSYGYPREEIVYQWK-RSSVEVGDTRSWRLYQFSFVGLRNTTEVVK 253
NFPMD +C ++ S+GY +++++W+ + +V+V D + L QF ++ K
Sbjct: 171 KNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLT--LPQFILKEEKDLRYCTK 228
Query: 254 T-TSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTV 312
+G + + F L R+MGY+ IQ YIP LIV+LSW+SFWIN DA PAR LGITTV
Sbjct: 229 HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTV 288
Query: 313 LTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKP-SKDKDK 371
LTMTT S+ +R SLPKVSYV A+D++++VC +FVFSAL+EY +++ K + + K
Sbjct: 289 LTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRK 348
Query: 372 KKKNPAPTIDIRPRSATIQMNNATHLQERDEEYGY--ECLDGKDCASFFCCFEDCRT--- 426
++ + +P +++ Q + A + YG CL KD S T
Sbjct: 349 RRHHKSPMLNL------FQEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPP 402
Query: 427 -----GAWRHGRIHI-RIAKMDSYARIFFPTAFCLFNLVYWVSY 464
++ I R K+D +RI FP AF +FN+ YW+ Y
Sbjct: 403 PAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIY 446
>gi|110347441 glycine receptor, alpha 3 isoform a [Homo sapiens]
Length = 464
Score = 266 bits (679), Expect = 4e-71
Identities = 149/409 (36%), Positives = 229/409 (55%), Gaps = 27/409 (6%)
Query: 76 GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNS-TIKV 134
GYD ++RP+ P + ++++NS G + M+Y ++IF Q W D RL ++
Sbjct: 56 GYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDS 115
Query: 135 LRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQL 194
L L+ +M+ IW PD FF N K A+ H +TT N++LRI+ +G VLY++RLT+ C + L
Sbjct: 116 LDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDL 175
Query: 195 HNFPMDEHSCPLEFSSYGYPREEIVYQWK-RSSVEVGDTRSWRLYQFSFVGLRNTTEVVK 253
NFPMD +C ++ S+GY +++++W+ + V+V + + L QF ++ K
Sbjct: 176 KNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLT--LPQFLLKEEKDLRYCTK 233
Query: 254 T-TSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTV 312
+G + + V F L R+MGY+ IQ YIP LIV+LSWVSFWIN DA PAR +LGITTV
Sbjct: 234 HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTV 293
Query: 313 LTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKK 372
LTMTT S+ +R SLPKVSYV A+D++++VC +FVFSAL+EY +++ K +K
Sbjct: 294 LTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRK 353
Query: 373 KKNPAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHG 432
+KN + M++ + R+ + + C +D T +
Sbjct: 354 RKNKTEAFALEKFYRFSDMDD----EVRESRFSFTAYGMGPCLQ----AKDGMTPKGPNH 405
Query: 433 RIHI--------------RIAKMDSYARIFFPTAFCLFNLVYWVSYLYL 467
+ + R K+D+ +R FP AF +FN+ YWV Y L
Sbjct: 406 PVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKIL 454
>gi|110347433 glycine receptor, alpha 3 isoform b [Homo sapiens]
Length = 449
Score = 263 bits (671), Expect = 3e-70
Identities = 155/413 (37%), Positives = 225/413 (54%), Gaps = 50/413 (12%)
Query: 76 GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNS-TIKV 134
GYD ++RP+ P + ++++NS G + M+Y ++IF Q W D RL ++
Sbjct: 56 GYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDS 115
Query: 135 LRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQL 194
L L+ +M+ IW PD FF N K A+ H +TT N++LRI+ +G VLY++RLT+ C + L
Sbjct: 116 LDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDL 175
Query: 195 HNFPMDEHSCPLEFSSYGYPREEIVYQWK-RSSVEVGDTRSWRLYQFSFVGLRNTTEVVK 253
NFPMD +C ++ S+GY +++++W+ + V+V + + L QF ++ K
Sbjct: 176 KNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLT--LPQFLLKEEKDLRYCTK 233
Query: 254 T-TSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTV 312
+G + + V F L R+MGY+ IQ YIP LIV+LSWVSFWIN DA PAR +LGITTV
Sbjct: 234 HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTV 293
Query: 313 LTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKK 372
LTMTT S+ +R SLPKVSYV A+D++++VC +FVFSAL+EY +++ K +K
Sbjct: 294 LTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRK 353
Query: 373 KKNPAPTIDIRPRSATIQMNNATHLQERDEEYGY-ECLDGKDCASFFCCFEDCRTGAWRH 431
+KN + S T YG CL KD G
Sbjct: 354 RKNKDDEVRESRFSFT--------------AYGMGPCLQAKD-------------GMTPK 386
Query: 432 GRIH-----------------IRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL 467
G H R K+D+ +R FP AF +FN+ YWV Y L
Sbjct: 387 GPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKIL 439
>gi|169646723 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 261 bits (668), Expect = 7e-70
Identities = 149/399 (37%), Positives = 221/399 (55%), Gaps = 24/399 (6%)
Query: 76 GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNS-TIKV 134
GYD ++RP+ P + ++++NS G V M+Y ++IF Q W D RL ++
Sbjct: 57 GYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDS 116
Query: 135 LRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQL 194
L L+ +M+ IW PD FF N K A+ H +TT N++LRI +G+VLY++RLT+ C + L
Sbjct: 117 LDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDL 176
Query: 195 HNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKT 254
NFPMD +C ++ S+GY +++++W S V L QF + K
Sbjct: 177 KNFPMDVQTCTMQLESFGYTMNDLIFEWL-SDGPVQVAEGLTLPQFILKEEKELGYCTKH 235
Query: 255 -TSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVL 313
+G + + V F L R+MGY+ IQ YIP LIV+LSWVSFWIN DA PAR +LGITTVL
Sbjct: 236 YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVL 295
Query: 314 TMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKK 373
TMTT S+ +R SLPKVSYV A+D++++VC +FVF+AL+EY +++ K +++
Sbjct: 296 TMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQ 355
Query: 374 KNPAPTIDIRPRSATIQMNNATHLQERDEEYGY---ECLDGKDCASFFC-----CFEDCR 425
K D+ S R GY CL KD + + +
Sbjct: 356 KRQNKEEDVTRES-------------RFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPK 402
Query: 426 TGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSY 464
G + R ++D+ +R FP AF +FN+ YW++Y
Sbjct: 403 DGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
>gi|4504021 glycine receptor, alpha 2 isoform A [Homo sapiens]
Length = 452
Score = 261 bits (668), Expect = 7e-70
Identities = 149/399 (37%), Positives = 221/399 (55%), Gaps = 24/399 (6%)
Query: 76 GYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNS-TIKV 134
GYD ++RP+ P + ++++NS G V M+Y ++IF Q W D RL ++
Sbjct: 57 GYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDS 116
Query: 135 LRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQL 194
L L+ +M+ IW PD FF N K A+ H +TT N++LRI +G+VLY++RLT+ C + L
Sbjct: 117 LDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDL 176
Query: 195 HNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKT 254
NFPMD +C ++ S+GY +++++W S V L QF + K
Sbjct: 177 KNFPMDVQTCTMQLESFGYTMNDLIFEWL-SDGPVQVAEGLTLPQFILKEEKELGYCTKH 235
Query: 255 -TSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVL 313
+G + + V F L R+MGY+ IQ YIP LIV+LSWVSFWIN DA PAR +LGITTVL
Sbjct: 236 YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVL 295
Query: 314 TMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKK 373
TMTT S+ +R SLPKVSYV A+D++++VC +FVF+AL+EY +++ K +++
Sbjct: 296 TMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQ 355
Query: 374 KNPAPTIDIRPRSATIQMNNATHLQERDEEYGY---ECLDGKDCASFFC-----CFEDCR 425
K D+ S R GY CL KD + + +
Sbjct: 356 KRQNKEEDVTRES-------------RFNFSGYGMGHCLQVKDGTAVKATPANPLPQPPK 402
Query: 426 TGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSY 464
G + R ++D+ +R FP AF +FN+ YW++Y
Sbjct: 403 DGDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWITY 441
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.137 0.434
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,660,504
Number of Sequences: 37866
Number of extensions: 763232
Number of successful extensions: 2249
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2090
Number of HSP's gapped (non-prelim): 100
length of query: 467
length of database: 18,247,518
effective HSP length: 106
effective length of query: 361
effective length of database: 14,233,722
effective search space: 5138373642
effective search space used: 5138373642
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.