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Search of human proteins with 38570149
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38570149 WWC family member 3 [Homo sapiens]
(1092 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38570149 WWC family member 3 [Homo sapiens] 2147 0.0
gi|156546890 WW and C2 domain containing 2 [Homo sapiens] 763 0.0
gi|29789058 WW and C2 domain containing 1 isoform 3 [Homo sapiens] 707 0.0
gi|242247257 WW and C2 domain containing 1 isoform 2 [Homo sapiens] 706 0.0
gi|242247251 WW and C2 domain containing 1 isoform 1 [Homo sapiens] 705 0.0
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 57 7e-08
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 57 7e-08
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 57 7e-08
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 57 7e-08
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 57 7e-08
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 57 7e-08
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 57 7e-08
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 57 7e-08
gi|56550043 sarcolemma associated protein [Homo sapiens] 56 2e-07
gi|34577114 cytomatrix protein p110 [Homo sapiens] 53 2e-06
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 52 3e-06
gi|169208042 PREDICTED: similar to Golgin subfamily A member 8-l... 49 2e-05
gi|169208038 PREDICTED: similar to Golgin subfamily A member 8-l... 49 2e-05
gi|16262452 cingulin [Homo sapiens] 49 2e-05
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 49 3e-05
gi|169208018 PREDICTED: similar to Golgin subfamily A member 8-l... 49 3e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 49 3e-05
gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 49 3e-05
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 49 3e-05
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 49 3e-05
gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-l... 48 4e-05
gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-l... 48 4e-05
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 48 4e-05
gi|156104908 myosin heavy chain 6 [Homo sapiens] 48 6e-05
gi|113425121 PREDICTED: similar to Golgin subfamily A member 8-l... 47 8e-05
>gi|38570149 WWC family member 3 [Homo sapiens]
Length = 1092
Score = 2147 bits (5564), Expect = 0.0
Identities = 1092/1092 (100%), Positives = 1092/1092 (100%)
Query: 1 MDHINKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQL 60
MDHINKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQL
Sbjct: 1 MDHINKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQL 60
Query: 61 HKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKG 120
HKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKG
Sbjct: 61 HKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKG 120
Query: 121 VETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKN 180
VETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKN
Sbjct: 121 VETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKN 180
Query: 181 SCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEE 240
SCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEE
Sbjct: 181 SCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEE 240
Query: 241 ARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARL 300
ARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARL
Sbjct: 241 ARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARL 300
Query: 301 EEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSLCAST 360
EEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSLCAST
Sbjct: 301 EEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSLCAST 360
Query: 361 LTVSSGSSRGSLASSRGSLASSRGSLSSVSFTDIYGLPQYEKPDAEGSQLLRFDLIPFDS 420
LTVSSGSSRGSLASSRGSLASSRGSLSSVSFTDIYGLPQYEKPDAEGSQLLRFDLIPFDS
Sbjct: 361 LTVSSGSSRGSLASSRGSLASSRGSLSSVSFTDIYGLPQYEKPDAEGSQLLRFDLIPFDS 420
Query: 421 LGRDAPFSEPPGPSGFHKQRRSLDTPQSLASLSSRSSLSSLSPPSSPLDTPFLPASRDSP 480
LGRDAPFSEPPGPSGFHKQRRSLDTPQSLASLSSRSSLSSLSPPSSPLDTPFLPASRDSP
Sbjct: 421 LGRDAPFSEPPGPSGFHKQRRSLDTPQSLASLSSRSSLSSLSPPSSPLDTPFLPASRDSP 480
Query: 481 LAQLADSCEGPGLGALDRLRAHASAMGDEDLPGMAALQPHGVPGDGEGPHERGPPPASAP 540
LAQLADSCEGPGLGALDRLRAHASAMGDEDLPGMAALQPHGVPGDGEGPHERGPPPASAP
Sbjct: 481 LAQLADSCEGPGLGALDRLRAHASAMGDEDLPGMAALQPHGVPGDGEGPHERGPPPASAP 540
Query: 541 VGGTVTLREDSAKRLERRARRISACLSDYSLASDSGVFEPLTKRNEDAEEPAYGDTASNG 600
VGGTVTLREDSAKRLERRARRISACLSDYSLASDSGVFEPLTKRNEDAEEPAYGDTASNG
Sbjct: 541 VGGTVTLREDSAKRLERRARRISACLSDYSLASDSGVFEPLTKRNEDAEEPAYGDTASNG 600
Query: 601 DPQIHVGLLRDSGSECLLVHVLQLKNPAGLAVKEDCKVHIRVYLPPLDSGTPNTYCSKAL 660
DPQIHVGLLRDSGSECLLVHVLQLKNPAGLAVKEDCKVHIRVYLPPLDSGTPNTYCSKAL
Sbjct: 601 DPQIHVGLLRDSGSECLLVHVLQLKNPAGLAVKEDCKVHIRVYLPPLDSGTPNTYCSKAL 660
Query: 661 EFQVPLVFNEVFRIPVHSSALTLKSLQLYVCSVTPQLQEELLGIAQINLADYDSLSEMQL 720
EFQVPLVFNEVFRIPVHSSALTLKSLQLYVCSVTPQLQEELLGIAQINLADYDSLSEMQL
Sbjct: 661 EFQVPLVFNEVFRIPVHSSALTLKSLQLYVCSVTPQLQEELLGIAQINLADYDSLSEMQL 720
Query: 721 RWHSVQVFTSSEPSRTREAGCAGESSARDPAHTISISGKTDAVTVLLARTTAQLQAVERE 780
RWHSVQVFTSSEPSRTREAGCAGESSARDPAHTISISGKTDAVTVLLARTTAQLQAVERE
Sbjct: 721 RWHSVQVFTSSEPSRTREAGCAGESSARDPAHTISISGKTDAVTVLLARTTAQLQAVERE 780
Query: 781 LAEERAKLEYTEEEVLEMERKEEQAEAISERSWQADSVDSGCSNCTQTSPPYPEPCCMGI 840
LAEERAKLEYTEEEVLEMERKEEQAEAISERSWQADSVDSGCSNCTQTSPPYPEPCCMGI
Sbjct: 781 LAEERAKLEYTEEEVLEMERKEEQAEAISERSWQADSVDSGCSNCTQTSPPYPEPCCMGI 840
Query: 841 DSILGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASLVKERPSRRARGSPFVR 900
DSILGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASLVKERPSRRARGSPFVR
Sbjct: 841 DSILGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASLVKERPSRRARGSPFVR 900
Query: 901 SGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVRNTLERRTLRYKQSCRSSLAE 960
SGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVRNTLERRTLRYKQSCRSSLAE
Sbjct: 901 SGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVRNTLERRTLRYKQSCRSSLAE 960
Query: 961 LMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQLRGQTDLPPWVLRDERLRG 1020
LMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQLRGQTDLPPWVLRDERLRG
Sbjct: 961 LMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQLRGQTDLPPWVLRDERLRG 1020
Query: 1021 LLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRGQSHKEPIQVQTFREKIAFFTRP 1080
LLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRGQSHKEPIQVQTFREKIAFFTRP
Sbjct: 1021 LLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRGQSHKEPIQVQTFREKIAFFTRP 1080
Query: 1081 RINIPPLPADDV 1092
RINIPPLPADDV
Sbjct: 1081 RINIPPLPADDV 1092
>gi|156546890 WW and C2 domain containing 2 [Homo sapiens]
Length = 1192
Score = 763 bits (1969), Expect = 0.0
Identities = 491/1136 (43%), Positives = 690/1136 (60%), Gaps = 63/1136 (5%)
Query: 1 MDHINKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQL 60
+DHINK TQIEDPR+QWR EQE+MLK+YL VAQ+AL +KE+Y +K+QR LA +EY +L
Sbjct: 76 IDHINKTTQIEDPRKQWRGEQEKMLKDYLSVAQDALRTQKELYHVKEQRLALALDEYVRL 135
Query: 61 HKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKG 120
+ ++ S S+ S FSG S++TKYDP +KAEI++ R R+ +LKREL+QMKQEL YKE+G
Sbjct: 136 NDAYKEKSSSHTSLFSGSSSSTKYDPDILKAEISTTRLRVKKLKRELSQMKQELLYKEQG 195
Query: 121 VETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKN 180
ETLQ+ID+KMS + Y+L EA+AI++EL++I+KAI +GEKE++DLM SLAKL + F
Sbjct: 196 FETLQQIDKKMSGGQSGYELSEAKAILTELKSIRKAISSGEKEKQDLMQSLAKLQERFHL 255
Query: 181 SCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEE 240
++ S D V + +Q DAGSQT I G+ ++ L ++VRL+ QYEE
Sbjct: 256 DQNIGRSEPDL-RCSPVNSHLCLSRQTLDAGSQTSISGDIGVRSRSNLAEKVRLSLQYEE 314
Query: 241 ARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARL 300
A++ +AN++ +L++LD+E+WP + ++++L LI EKE LL+ELQ + Q+R+ ++ RL
Sbjct: 315 AKRSMANLKIELSKLDSEAWPGALDIEKEKLMLINEKEELLKELQFVTPQKRTQDELERL 374
Query: 301 EEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSLCAST 360
E ER+RLEEEL R T ++ ER+ L+E+R LL +LEE T+LT+YL SQLKSL AST
Sbjct: 375 EAERQRLEEELLSVRGTPSRALAERLRLEERRKELLQKLEETTKLTTYLHSQLKSLSAST 434
Query: 361 LTVSSGSSRGSLASSRGSL-ASSRGSLSSVSFTDIYGLPQYEKPDAEGSQLLRFDLI--- 416
L++SSGSS GSLASSRGSL SSRGSL+S+S T++Y Q ++ D + L F L
Sbjct: 435 LSMSSGSSLGSLASSRGSLNTSSRGSLNSLSSTELYYSSQSDQIDVDYQYKLDFLLQEKS 494
Query: 417 ------PFDSLGRDAPFSEP--PGPSGFHKQRRS--------LDTPQSLASLSSRSSLSS 460
P ++ + P PG SG + + P+S+ASLSSRSSLSS
Sbjct: 495 GYIPSGPITTIHENEVVKSPSQPGQSGLCGVAAAATGHTPPLAEAPKSVASLSSRSSLSS 554
Query: 461 LSPPSSPL---DTPFLPASRDSPLAQLADSCEGPGLGA--LDRLRAHASAMGDEDLPGMA 515
LSPP SPL T + +S D+ L Q E L + D + D D G +
Sbjct: 555 LSPPGSPLVLEGTFPMSSSHDASLHQFTADFEDCELSSHFADISLIENQILLDSDSGGAS 614
Query: 516 ALQPHGVPGDGEGPHERGPPPASAPVGGTVTLREDSAKR-----LERRARRISACLSDYS 570
+ + +E P GT + + KR L + +SA +SD S
Sbjct: 615 QSL-----SEDKDLNECAREPL---YEGTADVEKSLPKRRVIHLLGEKTTCVSAAVSDES 666
Query: 571 LASDSGVFEPLTKRNEDAEEPAYG--DTASNGDPQIHVGLLRDSGSECLLVHVLQLKNPA 628
+A DSGV+E K+ + E+ Y D A Q+ +GL ++ S +V + QL+N
Sbjct: 667 VAGDSGVYEAFVKQPSEMEDVTYSEEDVAIVETAQVQIGLRYNAKSSSFMVIIAQLRNLH 726
Query: 629 GLAVKEDCKVHIRVYLPPLDSGTPNTYCSKALEFQVPLVFNEVFRIPVHSSALTLKSLQL 688
+ KV+ RV + P + + +K ++FN+VFR+ + +AL K+L++
Sbjct: 727 AFLIPHTSKVYFRVAVLPSSTDVSCLFRTKVHPPTESILFNDVFRVAISQTALQQKTLRV 786
Query: 689 YVCSVTPQLQEELLGIAQINLADYDSLSEMQLRWHSVQVFTSSEPSRTREAGCAGESSAR 748
+CSV+ +EE L QI+LAD SE+ W+++ + + P + E E S
Sbjct: 787 DLCSVSKHRREECLAGTQISLADLPFSSEVFTLWYNL-LPSKQMPCKKNE---ENEDSVF 842
Query: 749 DPAHTISISGKTDAVTVLLARTTAQLQAVERELAEERAKLEYTEE------EVLEMERKE 802
P + S DAV+ LLART+A+L AVE+ELA+E + EE + L M R E
Sbjct: 843 QPNQPLVDSIDLDAVSALLARTSAELLAVEQELAQEEEEESGQEEPRGPDGDWLTMLR-E 901
Query: 803 EQAEAISERSWQAD-SVDSGCSNCTQTSPPYPEPCCMGIDSILGHPFAAQAGPYSPEKFQ 861
E ++E+ + DS C+ + PE M D A+ P
Sbjct: 902 ASDEIVAEKEAEVKLPEDSSCTEDLSSCTSVPE---MNEDGNRKESNCAKDLRSQPP--T 956
Query: 862 PSPLKVDKETNTEDLFLEEAASLVKERPSRRARGSPFVRSGTIVRSQTFSPGARSQYVCR 921
P VDKETNT++ + A KER S +R PFVRS IVRSQTFSPG R+QY+CR
Sbjct: 957 RIPTLVDKETNTDEAANDNMAVRPKERSSLSSRQHPFVRSSVIVRSQTFSPGERNQYICR 1016
Query: 922 LYRSDSDSSTLPRKSPFVRNTLERRTLRYKQS-CRSSL----AELMARTSLDLELDLQAS 976
L RSDSDSSTL +KS FVRN+ ERR+LR K++ C+S L E RTSLDLELDLQAS
Sbjct: 1017 LNRSDSDSSTLAKKSLFVRNSTERRSLRVKRTVCQSVLRRTTQECPVRTSLDLELDLQAS 1076
Query: 977 RTRQRQLNEELCALRELRQRLEDAQLRGQTDLPPWVLRDERLRGLLREAERQTRQTKLDY 1036
TRQ +LN+EL ALR+LRQ+LE+ + +G+TDLPP VL DER + LL++AE+Q Q+K +
Sbjct: 1077 LTRQSRLNDELQALRDLRQKLEELKAQGETDLPPGVLEDERFQRLLKQAEKQAEQSKEEQ 1136
Query: 1037 RHEQAAEKMLKKASKEIYQLRGQSHKEPIQVQTFREKIAFFTRPRINIPPLPADDV 1092
+ AEK++++ SK++ +LR QS K P QVQ+FREKIA+FTR +I+IP LPADDV
Sbjct: 1137 KQGLNAEKLMRQVSKDVCRLREQSQKVPRQVQSFREKIAYFTRAKISIPSLPADDV 1192
>gi|29789058 WW and C2 domain containing 1 isoform 3 [Homo sapiens]
Length = 1113
Score = 707 bits (1826), Expect = 0.0
Identities = 467/1114 (41%), Positives = 654/1114 (58%), Gaps = 94/1114 (8%)
Query: 1 MDHINKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQL 60
+DH K TQIEDPR QWRREQE MLK+YL+VAQEAL+A+KEIYQ+KQQR ELAQ+EYQQL
Sbjct: 72 IDHNTKTTQIEDPRVQWRREQEHMLKDYLVVAQEALSAQKEIYQVKQQRLELAQQEYQQL 131
Query: 61 HKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKG 120
H + E S S SG S+++KYDP +KAEIA+ + R+++LKRE+ ++ ELQ+KE+G
Sbjct: 132 HAVWEHKLGSQVSLVSGSSSSSKYDPEILKAEIATAKSRVNKLKREMVHLQHELQFKERG 191
Query: 121 VETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKN 180
+TL++ID+KMS SYKLDEAQA++ E + IKKAI GEKE++DL+ SLA L D F+
Sbjct: 192 FQTLKKIDKKMSDAQGSYKLDEAQAVLRETKAIKKAITCGEKEKQDLIKSLAMLKDGFRT 251
Query: 181 SCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEE 240
L + +P+Q+ D SQTDI G F + +L ++VRL +YEE
Sbjct: 252 DRGSHSDLWSSSSSL-ESSSFPLPKQYLDVSSQTDISGSFGINSNNQLAEKVRLRLRYEE 310
Query: 241 ARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARL 300
A++R+AN++ QLA+LD+E+WP +++RDRL LI EKE LL+E++ I ++ + G+V +L
Sbjct: 311 AKRRIANLKIQLAKLDSEAWPGVLDSERDRLILINEKEELLKEMRFISPRKWTQGEVEQL 370
Query: 301 EEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSLCAST 360
E R+RLE++L+ AR T ++ TER+ L KRN L+ +LEEATR + L SQLKSL +S
Sbjct: 371 EMARKRLEKDLQAARDTQSKALTERLKLNSKRNQLVRELEEATRQVATLHSQLKSLSSSM 430
Query: 361 LTVSSGSSRGSLASSRGSL-ASSRGSLSSVSFTDIYGLPQYEKPDAEGSQLLRFDLIP-- 417
++SSGSS GSL SSRGSL ASS S +S SFTD+Y P +E+ D+E + F L+
Sbjct: 431 QSLSSGSSPGSLTSSRGSLVASSLDSSTSASFTDLYYDP-FEQLDSELQSKVEFLLLEGA 489
Query: 418 --------FDSLGRD--APFSEPPGPSGFHKQRRSLDTPQSLASLSSRSSLSSLSPPSSP 467
++ D A + G R TP+S+ SLS RSSLSS SPP SP
Sbjct: 490 TGFRPSGCITTIHEDEVAKTQKAEGGGRLQALRSLSGTPKSMTSLSPRSSLSSPSPPCSP 549
Query: 468 LDTPFLPASRDSPLAQLADSCEGPGLGALDRLRAHASAMGDEDLPGMAALQPHGVPGDGE 527
L L A D+ L L E P L A + + L G
Sbjct: 550 LMADPLLAG-DAFLNSL--EFEDPELSA---------TLCELSL--------------GN 583
Query: 528 GPHERGPPPASAPVGGTVTLREDSAKRLERRARRISACLSDYSLASDSGVFEPLTKRNED 587
ER G + ++A+ + +SA +SD S+A DSGV+E +R
Sbjct: 584 SAQERYRLEEPGTEGKQLGQAVNTAQGCGLKVACVSAAVSDESVAGDSGVYEASVQRLGA 643
Query: 588 AEEPAYGDTASN--GDPQIHVGLLRDSGSECLLVHVLQLKNPAGLAVKEDCKVHIRVYLP 645
+E A+ S G +I + L D ++ + ++QL N + L ++D KV+IRV +
Sbjct: 644 SEAAAFDSDESEAVGATRIQIALKYDEKNKQFAILIIQLSNLSALLQQQDQKVNIRVAVL 703
Query: 646 PLDSGTPNTYCSKALEFQVPLVFNEVFRIPVHSSALTLKSLQLYVCSVTPQLQEELLGIA 705
P T + ++ L+ LVFNEVF + + AL K+L++ VC+ EE LG A
Sbjct: 704 PCSESTTCLFRTRPLDASDTLVFNEVFWVSMSYPALHQKTLRVDVCTTDRSHLEECLGGA 763
Query: 706 QINLADYDSLSEMQLRWHSVQVFTSSEPSRTREAGCAG-ESSARDPAHTISISGKTDAVT 764
QI+LA+ E RW+++ + + ++RE G + A PA TDAV+
Sbjct: 764 QISLAEVCRSGERSTRWYNLLSYKYLK-KQSRELKPVGVMAPASGPA-------STDAVS 815
Query: 765 VLLARTTAQLQAVERELAEERAKLEYTEEEVLEMERKEEQAEAISERSWQADSVDSGCSN 824
LL +T AVE E +E T E+ E E EA++E + + G +
Sbjct: 816 ALLEQT-----AVELEKRQEGRSSTQTLEDSWRYEETSEN-EAVAEEEEEEVEEEEGEED 869
Query: 825 CTQTSPPYPEPCCMGIDSILGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASL 884
F +A SP+ LKVDKETNTE A S
Sbjct: 870 V----------------------FTEKA---SPDMDGYPALKVDKETNTE----TPAPSP 900
Query: 885 VKERPSRRARGS----PFVRSGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVR 940
RP R G+ PF+R TI+RS+TFSPG +SQYVCRL RSDSDSSTL +K PFVR
Sbjct: 901 TVVRPKDRRVGTPSQGPFLRGSTIIRSKTFSPGPQSQYVCRLNRSDSDSSTLSKKPPFVR 960
Query: 941 NTLERRTLRYKQ--SCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLE 998
N+LERR++R K+ S +S +E + RTSLDLELDLQA+RT QL +E+ L+EL+++LE
Sbjct: 961 NSLERRSVRMKRPSSVKSLRSERLIRTSLDLELDLQATRTWHSQLTQEISVLKELKEQLE 1020
Query: 999 DAQLRGQTDLPPWVLRDERLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRG 1058
A+ G+ +LP W+ DER R LLR E++ + + +++ E +KM++ A+K++++LRG
Sbjct: 1021 QAKSHGEKELPQWLREDERFRLLLRMLEKR-QMDRAEHKGELQTDKMMRAAAKDVHRLRG 1079
Query: 1059 QSHKEPIQVQTFREKIAFFTRPRINIPPLPADDV 1092
QS KEP +VQ+FREK+AFFTRPR+NIP L ADDV
Sbjct: 1080 QSCKEPPEVQSFREKMAFFTRPRMNIPALSADDV 1113
>gi|242247257 WW and C2 domain containing 1 isoform 2 [Homo sapiens]
Length = 1118
Score = 706 bits (1822), Expect = 0.0
Identities = 468/1120 (41%), Positives = 653/1120 (58%), Gaps = 101/1120 (9%)
Query: 1 MDHINKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQL 60
+DH K TQIEDPR QWRREQE MLK+YL+VAQEAL+A+KEIYQ+KQQR ELAQ+EYQQL
Sbjct: 72 IDHNTKTTQIEDPRVQWRREQEHMLKDYLVVAQEALSAQKEIYQVKQQRLELAQQEYQQL 131
Query: 61 HKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKG 120
H + E S S SG S+++KYDP +KAEIA+ + R+++LKRE+ ++ ELQ+KE+G
Sbjct: 132 HAVWEHKLGSQVSLVSGSSSSSKYDPEILKAEIATAKSRVNKLKREMVHLQHELQFKERG 191
Query: 121 VETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKN 180
+TL++ID+KMS SYKLDEAQA++ E + IKKAI GEKE++DL+ SLA L D F+
Sbjct: 192 FQTLKKIDKKMSDAQGSYKLDEAQAVLRETKAIKKAITCGEKEKQDLIKSLAMLKDGFRT 251
Query: 181 SCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEE 240
L + +P+Q+ D SQTDI G F + +L ++VRL +YEE
Sbjct: 252 DRGSHSDLWSSSSSL-ESSSFPLPKQYLDVSSQTDISGSFGINSNNQLAEKVRLRLRYEE 310
Query: 241 ARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARL 300
A++R+AN++ QLA+LD+E+WP +++RDRL LI EKE LL+E++ I ++ + G+V +L
Sbjct: 311 AKRRIANLKIQLAKLDSEAWPGVLDSERDRLILINEKEELLKEMRFISPRKWTQGEVEQL 370
Query: 301 EEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSLCAST 360
E R+RLE++L+ AR T ++ TER+ L KRN L+ +LEEATR + L SQLKSL +S
Sbjct: 371 EMARKRLEKDLQAARDTQSKALTERLKLNSKRNQLVRELEEATRQVATLHSQLKSLSSSM 430
Query: 361 LTVSSGSSRGSLASSRGSL-ASSRGSLSSVSFTDIYGLPQYEKPDAEGSQLLRFDLIP-- 417
++SSGSS GSL SSRGSL ASS S +S SFTD+Y P +E+ D+E + F L+
Sbjct: 431 QSLSSGSSPGSLTSSRGSLVASSLDSSTSASFTDLYYDP-FEQLDSELQSKVEFLLLEGA 489
Query: 418 --------FDSLGRD--APFSEPPGPSGFHKQRRSLDTPQSLASLSSRSSLSSLSPPSSP 467
++ D A + G R TP+S+ SLS RSSLSS SPP SP
Sbjct: 490 TGFRPSGCITTIHEDEVAKTQKAEGGGRLQALRSLSGTPKSMTSLSPRSSLSSPSPPCSP 549
Query: 468 LDTPFLPASRDSPLAQLADSCEGPGLGALDRLRAHASAMGDEDLPGMAALQPHGVPGDGE 527
L L A D+ L L E P L A + + L G
Sbjct: 550 LMADPLLAG-DAFLNSL--EFEDPELSA---------TLCELSL--------------GN 583
Query: 528 GPHERGPPPASAPVGGTVTLREDSAKRLERRARRISACLSDYSLASDSGVFEPLTKRNED 587
ER G + ++A+ + +SA +SD S+A DSGV+E +R
Sbjct: 584 SAQERYRLEEPGTEGKQLGQAVNTAQGCGLKVACVSAAVSDESVAGDSGVYEASVQRLGA 643
Query: 588 AEEPAYGDTASN--GDPQIHVGLLRDSGSECLLVHVLQLKNPAGLAVKEDCKVHIRVYLP 645
+E A+ S G +I + L D ++ + ++QL N + L ++D KV+IRV +
Sbjct: 644 SEAAAFDSDESEAVGATRIQIALKYDEKNKQFAILIIQLSNLSALLQQQDQKVNIRVAVL 703
Query: 646 PLDSGTPNTYCSKALEFQVPLVFNEVFRIPVHSSALTLKSLQLYVCSVTPQLQEELLGIA 705
P T + ++ L+ LVFNEVF + + AL K+L++ VC+ EE LG A
Sbjct: 704 PCSESTTCLFRTRPLDASDTLVFNEVFWVSMSYPALHQKTLRVDVCTTDRSHLEECLGGA 763
Query: 706 QINLADYDSLSEMQLRWHSVQVFTSSEPSRTREAGCAG-ESSARDPAHTISISGKTDAVT 764
QI+LA+ E RW+++ + + ++RE G + A PA TDAV+
Sbjct: 764 QISLAEVCRSGERSTRWYNLLSYKYLK-KQSRELKPVGVMAPASGPA-------STDAVS 815
Query: 765 VLLARTTAQLQAVERELAEERAKLEYTEEEVLEMERKEEQAEAISERSWQADSVDSGCSN 824
LL +T AVE E +E T E+ E E EA++E + + G +
Sbjct: 816 ALLEQT-----AVELEKRQEGRSSTQTLEDSWRYEETSEN-EAVAEEEEEEVEEEEGEED 869
Query: 825 CTQTSPPYPEPCCMGIDSILGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASL 884
F +A SP+ LKVDKETNTE A S
Sbjct: 870 V----------------------FTEKA---SPDMDGYPALKVDKETNTE----TPAPSP 900
Query: 885 VKERPSRRARGS----PFVRSGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVR 940
RP R G+ PF+R TI+RS+TFSPG +SQYVCRL RSDSDSSTL +K PFVR
Sbjct: 901 TVVRPKDRRVGTPSQGPFLRGSTIIRSKTFSPGPQSQYVCRLNRSDSDSSTLSKKPPFVR 960
Query: 941 NTLERRTLRYKQ--------SCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRE 992
N+LERR++R K+ S +S +E + RTSLDLELDLQA+RT QL +E+ L+E
Sbjct: 961 NSLERRSVRMKRPSPPPQPSSVKSLRSERLIRTSLDLELDLQATRTWHSQLTQEISVLKE 1020
Query: 993 LRQRLEDAQLRGQTDLPPWVLRDERLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKE 1052
L+++LE A+ G+ +LP W+ DER R LLR E+ R + +++ E +KM++ A+K+
Sbjct: 1021 LKEQLEQAKSHGEKELPQWLREDERFRLLLRMLEK--RMDRAEHKGELQTDKMMRAAAKD 1078
Query: 1053 IYQLRGQSHKEPIQVQTFREKIAFFTRPRINIPPLPADDV 1092
+++LRGQS KEP +VQ+FREK+AFFTRPR+NIP L ADDV
Sbjct: 1079 VHRLRGQSCKEPPEVQSFREKMAFFTRPRMNIPALSADDV 1118
>gi|242247251 WW and C2 domain containing 1 isoform 1 [Homo sapiens]
Length = 1119
Score = 705 bits (1820), Expect = 0.0
Identities = 467/1120 (41%), Positives = 654/1120 (58%), Gaps = 100/1120 (8%)
Query: 1 MDHINKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQL 60
+DH K TQIEDPR QWRREQE MLK+YL+VAQEAL+A+KEIYQ+KQQR ELAQ+EYQQL
Sbjct: 72 IDHNTKTTQIEDPRVQWRREQEHMLKDYLVVAQEALSAQKEIYQVKQQRLELAQQEYQQL 131
Query: 61 HKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKG 120
H + E S S SG S+++KYDP +KAEIA+ + R+++LKRE+ ++ ELQ+KE+G
Sbjct: 132 HAVWEHKLGSQVSLVSGSSSSSKYDPEILKAEIATAKSRVNKLKREMVHLQHELQFKERG 191
Query: 121 VETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKN 180
+TL++ID+KMS SYKLDEAQA++ E + IKKAI GEKE++DL+ SLA L D F+
Sbjct: 192 FQTLKKIDKKMSDAQGSYKLDEAQAVLRETKAIKKAITCGEKEKQDLIKSLAMLKDGFRT 251
Query: 181 SCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEE 240
L + +P+Q+ D SQTDI G F + +L ++VRL +YEE
Sbjct: 252 DRGSHSDLWSSSSSL-ESSSFPLPKQYLDVSSQTDISGSFGINSNNQLAEKVRLRLRYEE 310
Query: 241 ARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARL 300
A++R+AN++ QLA+LD+E+WP +++RDRL LI EKE LL+E++ I ++ + G+V +L
Sbjct: 311 AKRRIANLKIQLAKLDSEAWPGVLDSERDRLILINEKEELLKEMRFISPRKWTQGEVEQL 370
Query: 301 EEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSLCAST 360
E R+RLE++L+ AR T ++ TER+ L KRN L+ +LEEATR + L SQLKSL +S
Sbjct: 371 EMARKRLEKDLQAARDTQSKALTERLKLNSKRNQLVRELEEATRQVATLHSQLKSLSSSM 430
Query: 361 LTVSSGSSRGSLASSRGSL-ASSRGSLSSVSFTDIYGLPQYEKPDAEGSQLLRFDLIP-- 417
++SSGSS GSL SSRGSL ASS S +S SFTD+Y P +E+ D+E + F L+
Sbjct: 431 QSLSSGSSPGSLTSSRGSLVASSLDSSTSASFTDLYYDP-FEQLDSELQSKVEFLLLEGA 489
Query: 418 --------FDSLGRD--APFSEPPGPSGFHKQRRSLDTPQSLASLSSRSSLSSLSPPSSP 467
++ D A + G R TP+S+ SLS RSSLSS SPP SP
Sbjct: 490 TGFRPSGCITTIHEDEVAKTQKAEGGGRLQALRSLSGTPKSMTSLSPRSSLSSPSPPCSP 549
Query: 468 LDTPFLPASRDSPLAQLADSCEGPGLGALDRLRAHASAMGDEDLPGMAALQPHGVPGDGE 527
L L A D+ L L E P L A + + L G
Sbjct: 550 LMADPLLAG-DAFLNSL--EFEDPELSA---------TLCELSL--------------GN 583
Query: 528 GPHERGPPPASAPVGGTVTLREDSAKRLERRARRISACLSDYSLASDSGVFEPLTKRNED 587
ER G + ++A+ + +SA +SD S+A DSGV+E +R
Sbjct: 584 SAQERYRLEEPGTEGKQLGQAVNTAQGCGLKVACVSAAVSDESVAGDSGVYEASVQRLGA 643
Query: 588 AEEPAYGDTASN--GDPQIHVGLLRDSGSECLLVHVLQLKNPAGLAVKEDCKVHIRVYLP 645
+E A+ S G +I + L D ++ + ++QL N + L ++D KV+IRV +
Sbjct: 644 SEAAAFDSDESEAVGATRIQIALKYDEKNKQFAILIIQLSNLSALLQQQDQKVNIRVAVL 703
Query: 646 PLDSGTPNTYCSKALEFQVPLVFNEVFRIPVHSSALTLKSLQLYVCSVTPQLQEELLGIA 705
P T + ++ L+ LVFNEVF + + AL K+L++ VC+ EE LG A
Sbjct: 704 PCSESTTCLFRTRPLDASDTLVFNEVFWVSMSYPALHQKTLRVDVCTTDRSHLEECLGGA 763
Query: 706 QINLADYDSLSEMQLRWHSVQVFTSSEPSRTREAGCAG-ESSARDPAHTISISGKTDAVT 764
QI+LA+ E RW+++ + + ++RE G + A PA TDAV+
Sbjct: 764 QISLAEVCRSGERSTRWYNLLSYKYLK-KQSRELKPVGVMAPASGPA-------STDAVS 815
Query: 765 VLLARTTAQLQAVERELAEERAKLEYTEEEVLEMERKEEQAEAISERSWQADSVDSGCSN 824
LL +T AVE E +E T E+ E E EA++E + + G +
Sbjct: 816 ALLEQT-----AVELEKRQEGRSSTQTLEDSWRYEETSEN-EAVAEEEEEEVEEEEGEED 869
Query: 825 CTQTSPPYPEPCCMGIDSILGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASL 884
F +A SP+ LKVDKETNTE A S
Sbjct: 870 V----------------------FTEKA---SPDMDGYPALKVDKETNTE----TPAPSP 900
Query: 885 VKERPSRRARGS----PFVRSGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVR 940
RP R G+ PF+R TI+RS+TFSPG +SQYVCRL RSDSDSSTL +K PFVR
Sbjct: 901 TVVRPKDRRVGTPSQGPFLRGSTIIRSKTFSPGPQSQYVCRLNRSDSDSSTLSKKPPFVR 960
Query: 941 NTLERRTLRYKQ--------SCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRE 992
N+LERR++R K+ S +S +E + RTSLDLELDLQA+RT QL +E+ L+E
Sbjct: 961 NSLERRSVRMKRPSPPPQPSSVKSLRSERLIRTSLDLELDLQATRTWHSQLTQEISVLKE 1020
Query: 993 LRQRLEDAQLRGQTDLPPWVLRDERLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKE 1052
L+++LE A+ G+ +LP W+ DER R LLR E++ + + +++ E +KM++ A+K+
Sbjct: 1021 LKEQLEQAKSHGEKELPQWLREDERFRLLLRMLEKR-QMDRAEHKGELQTDKMMRAAAKD 1079
Query: 1053 IYQLRGQSHKEPIQVQTFREKIAFFTRPRINIPPLPADDV 1092
+++LRGQS KEP +VQ+FREK+AFFTRPR+NIP L ADDV
Sbjct: 1080 VHRLRGQSCKEPPEVQSFREKMAFFTRPRMNIPALSADDV 1119
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 57.4 bits (137), Expect = 7e-08
Identities = 78/346 (22%), Positives = 142/346 (41%), Gaps = 40/346 (11%)
Query: 11 EDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRS 70
E+ Q R E+MLKE + QEA K E ++QQ+ ELAQE+ ++L + E ++
Sbjct: 2298 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQK-ELAQEQARRLQEDKEQMAQQ 2356
Query: 71 YASSFSGYSTNTKYDPH---QIKAEIASRRDRLSRLKRELTQMKQELQ-YKEKGVETLQE 126
A G+ + + ++ AE + R++ + R + +++ Q ++++ E ++
Sbjct: 2357 LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2416
Query: 127 IDRKMSSTHTSYKLDEAQAIMSE-----LRTIKKAICTGEKERRDLMHSLAKLTDSFKNS 181
+ R +T L + I + +++AI E+E+ L L +
Sbjct: 2417 LHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2476
Query: 182 CSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLV----DRVRLNWQ 237
+V + + + Q F F+ +K +L D V Q
Sbjct: 2477 QTVQQEQL-------LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ 2529
Query: 238 YEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDV 297
E ++R QQQ+ + S EA R + + + +ELQ + QRR ++
Sbjct: 2530 LREEQQRQ---QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEEL 2586
Query: 298 ARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEAT 343
L EE +RL E+L+ LL+E+ L EE T
Sbjct: 2587 --LAEENQRLREQLQ--------------LLEEQHRAALAHSEEVT 2616
Score = 52.8 bits (125), Expect = 2e-06
Identities = 79/363 (21%), Positives = 152/363 (41%), Gaps = 55/363 (15%)
Query: 34 EALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEI 93
+AL A+ E + ++++ AQEE ++L + +D+S+ Q + E+
Sbjct: 1476 QALRARAEEAEAQKRQ---AQEEAERLRRQVQDESQR---------------KRQAEVEL 1517
Query: 94 ASRRDRLSRLKRELTQMKQELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTI 153
ASR + RE + Q L+ E E +R++ +++ A+ + L T
Sbjct: 1518 ASRVKAEAEAAREKQRALQALEELRLQAE---EAERRLRQA----EVERARQVQVALETA 1570
Query: 154 KKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQ 213
+++ E E + S A+ T + S HV V ++ + +Q
Sbjct: 1571 QRS---AEAELQSKRASFAEKTAQLERSLQ--------EEHVAV----AQLREEAERRAQ 1615
Query: 214 TDIIGEFVFDDKTRLVDR--------VRLNWQYEEARKRVANIQQQLARLDNESWPSTAE 265
E ++ R ++R +RL Q EE ++ + Q + + E+
Sbjct: 1616 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARR 1675
Query: 266 ADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEERERLEEELRRARATSAQGATER 325
+ Q ++++E QEL+ QR+ A A ++R E+EL R RA + QG +R
Sbjct: 1676 RGKAEEQAVRQRELAEQELE---KQRQLAEGTA---QQRLAAEQELIRLRAETEQGEQQR 1729
Query: 326 ILLQEKRNCLLMQLEEATRLTSYLQSQLKSLCASTLTVSSGSSRGSLASSRGSLASSRGS 385
LL+E+ L + AT+ L+++L + A + + +R SR + S+
Sbjct: 1730 QLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAE-EESRSTSEKSKQR 1788
Query: 386 LSS 388
L +
Sbjct: 1789 LEA 1791
Score = 42.4 bits (98), Expect = 0.002
Identities = 72/388 (18%), Positives = 154/388 (39%), Gaps = 37/388 (9%)
Query: 2 DHINKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLH 61
+ + Q + E+ R E ER L+ + + A EAL + + ++ QQ+ LAQ E ++
Sbjct: 1608 EEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQK-SLAQAEAEKQK 1666
Query: 62 KMCEDDSRSYASSFSGYSTNTKYDPHQIKAE------IASRR----DRLSRLKRELTQMK 111
+ E ++R + + +++ + A +R L RL+ E Q +
Sbjct: 1667 EEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE 1726
Query: 112 QELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSL 171
Q+ Q E+ + LQ + + K E +A ++++R E L+ S
Sbjct: 1727 QQRQLLEEELARLQR-----EAAAATQKRQELEAELAKVRA----------EMEVLLASK 1771
Query: 172 AKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVD- 230
A+ + +++ + ++ +AG ++ + ++ + E + +
Sbjct: 1772 ARAEEESRSTSEKSKQRLE--------AEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1823
Query: 231 --RVRLNWQYEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLII 288
R R + A K A + + + E EA+ +RL+ + E EA +
Sbjct: 1824 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1883
Query: 289 AQRRSAGDVARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSY 348
A + A RL + R+ + EL R + +R ++E+ L E+A +
Sbjct: 1884 AAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAE 1943
Query: 349 LQSQLKSLCASTLTVSSGSSRGSLASSR 376
L+ +L + ++ + L ++R
Sbjct: 1944 LELELGRIRSNAEDTLRSKEQAELEAAR 1971
Score = 42.0 bits (97), Expect = 0.003
Identities = 67/353 (18%), Positives = 142/353 (40%), Gaps = 77/353 (21%)
Query: 9 QIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDS 68
Q+ E+ RRE E +++ L +EA +K + + +R + EE ++L + E +S
Sbjct: 1974 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQES 2032
Query: 69 RSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKG-VETLQEI 127
Q+ E A +R LQ +EK +Q+
Sbjct: 2033 ARQL---------------QLAQEAAQKR----------------LQAEEKAHAFAVQQK 2061
Query: 128 DRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDS 187
++++ T L + Q+++ +LR +A +E + + + +
Sbjct: 2062 EQELQQT-----LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2116
Query: 188 LVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEEARK---- 243
L ++ A +Q E ++R + E AR+
Sbjct: 2117 LKQSA------------EEQAQARAQAQAAAE-----------KLRKEAEQEAARRAQAE 2153
Query: 244 RVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEE 303
+ A Q+Q A + E AE Q +++K + QEL + Q + + +
Sbjct: 2154 QAALRQKQAADAEMEKHKKFAE------QTLRQKAQVEQELTTLRLQ------LEETDHQ 2201
Query: 304 RERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSL 356
+ L+EEL+R +A + + A +R ++E+ + +Q+EE ++L + ++++ ++L
Sbjct: 2202 KNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRAL 2254
Score = 37.7 bits (86), Expect = 0.060
Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 8/132 (6%)
Query: 942 TLERRTLRYKQSCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQ 1001
T +R QS R+S AE A+ LE LQ QL EE + + E A+
Sbjct: 1569 TAQRSAEAELQSKRASFAEKTAQ----LERSLQEEHVAVAQLREEAERRAQQQAEAERAR 1624
Query: 1002 LRGQTDLPPWVLRDERLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRGQSH 1061
+ +L W L+ L +AE +Q L + AEK ++A +E + RG++
Sbjct: 1625 EEAERELERWQLKANEALRLRLQAEEVAQQKSL---AQAEAEKQKEEAEREA-RRRGKAE 1680
Query: 1062 KEPIQVQTFREK 1073
++ ++ + E+
Sbjct: 1681 EQAVRQRELAEQ 1692
Score = 36.2 bits (82), Expect = 0.17
Identities = 84/369 (22%), Positives = 147/369 (39%), Gaps = 51/369 (13%)
Query: 732 EPSRTREAGCAGESSARDPAHTI--SISGKTDAVTVLLARTTAQLQAVER---ELAEERA 786
E +R R+ E R+ + S++ + +A + A L+ VER ++ E R
Sbjct: 1968 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR----QRKAALEEVERLKAKVEEARR 2023
Query: 787 KLEYTEEEV---LEMERKEEQAEAISERSWQADSVDSGCSNCTQTSPPYPEPCCMGIDSI 843
E E+E L++ ++ Q +E A +V QT +D +
Sbjct: 2024 LRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQL 2079
Query: 844 LGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASL---VKERPSRRARGSPFVR 900
G A+A + E+ + + ++ ++E +EEA L +E+ RA+
Sbjct: 2080 RGE---AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2136
Query: 901 SGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVRNTLERRTLRYKQSCRSSLAE 960
Q + A+++ + +D+ K +TLR K L
Sbjct: 2137 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK------FAEQTLRQKAQVEQELTT 2190
Query: 961 LMARTS--------LDLELD-LQASRT---RQR-QLNEELCALRELRQRLEDAQLRGQTD 1007
L + LD EL L+A T RQR Q+ EEL ++R + L + R + +
Sbjct: 2191 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2250
Query: 1008 LPPWVLRDE--RLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRGQSHKEPI 1065
+LRD+ R L EAE K+ E+AA L A++E +LR + ++
Sbjct: 2251 NRALILRDKDNTQRFLQEEAE------KMKQVAEEAAR--LSVAAQEAARLRQLAEEDLA 2302
Query: 1066 QVQTFREKI 1074
Q + EK+
Sbjct: 2303 QQRALAEKM 2311
Score = 33.1 bits (74), Expect = 1.5
Identities = 68/357 (19%), Positives = 139/357 (38%), Gaps = 30/357 (8%)
Query: 717 EMQLRWHSVQVFTSSEPSRTREAGCAGESSARD----PAHTISISGKTDAVTVLLARTTA 772
E+QL + Q+ + P++ + ES ++ H ++ T ++ T
Sbjct: 1283 ELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLR 1342
Query: 773 QLQAVERELAEERAK-LEYTEEEVLEMERKEEQAEAISERSWQADSVDSGCSNCTQTSPP 831
+++ ER ++RA+ E E +E++ + AEA ++ QA+ Q
Sbjct: 1343 RMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ---- 1398
Query: 832 YPEPCCMGIDSILGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASLVKERPSR 891
+ ++ AA Q L+ ++++ ++ + + ER
Sbjct: 1399 ---------EEVVRREEAAVDAQQQKRSIQEE-LQQLRQSSEAEIQAKARQAEAAERSRL 1448
Query: 892 RARGSPFVRSGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVRNTLERRTLRYK 951
R V + ++ GA + R++ ++ R++ L R+
Sbjct: 1449 RIEEEIRVVRLQLEATERQRGGAEGELQALRARAE-EAEAQKRQAQEEAERLRRQVQDES 1507
Query: 952 QSCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQLR-GQTDLPP 1010
Q R + EL +R + E A+R +QR L AL ELR + E+A+ R Q ++
Sbjct: 1508 QRKRQAEVELASRVKAEAE----AAREKQRALQ----ALEELRLQAEEAERRLRQAEVER 1559
Query: 1011 WVLRDERLRGLLREAERQTRQTKLDYRHEQA-AEKMLKKASKEIYQLRGQSHKEPIQ 1066
L R AE + + + + + A E+ L++ + QLR ++ + Q
Sbjct: 1560 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1616
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 57.4 bits (137), Expect = 7e-08
Identities = 78/346 (22%), Positives = 142/346 (41%), Gaps = 40/346 (11%)
Query: 11 EDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRS 70
E+ Q R E+MLKE + QEA K E ++QQ+ ELAQE+ ++L + E ++
Sbjct: 2302 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQK-ELAQEQARRLQEDKEQMAQQ 2360
Query: 71 YASSFSGYSTNTKYDPH---QIKAEIASRRDRLSRLKRELTQMKQELQ-YKEKGVETLQE 126
A G+ + + ++ AE + R++ + R + +++ Q ++++ E ++
Sbjct: 2361 LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2420
Query: 127 IDRKMSSTHTSYKLDEAQAIMSE-----LRTIKKAICTGEKERRDLMHSLAKLTDSFKNS 181
+ R +T L + I + +++AI E+E+ L L +
Sbjct: 2421 LHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2480
Query: 182 CSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLV----DRVRLNWQ 237
+V + + + Q F F+ +K +L D V Q
Sbjct: 2481 QTVQQEQL-------LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ 2533
Query: 238 YEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDV 297
E ++R QQQ+ + S EA R + + + +ELQ + QRR ++
Sbjct: 2534 LREEQQRQ---QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEEL 2590
Query: 298 ARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEAT 343
L EE +RL E+L+ LL+E+ L EE T
Sbjct: 2591 --LAEENQRLREQLQ--------------LLEEQHRAALAHSEEVT 2620
Score = 52.8 bits (125), Expect = 2e-06
Identities = 79/363 (21%), Positives = 152/363 (41%), Gaps = 55/363 (15%)
Query: 34 EALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEI 93
+AL A+ E + ++++ AQEE ++L + +D+S+ Q + E+
Sbjct: 1480 QALRARAEEAEAQKRQ---AQEEAERLRRQVQDESQR---------------KRQAEVEL 1521
Query: 94 ASRRDRLSRLKRELTQMKQELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTI 153
ASR + RE + Q L+ E E +R++ +++ A+ + L T
Sbjct: 1522 ASRVKAEAEAAREKQRALQALEELRLQAE---EAERRLRQA----EVERARQVQVALETA 1574
Query: 154 KKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQ 213
+++ E E + S A+ T + S HV V ++ + +Q
Sbjct: 1575 QRS---AEAELQSKRASFAEKTAQLERSLQ--------EEHVAV----AQLREEAERRAQ 1619
Query: 214 TDIIGEFVFDDKTRLVDR--------VRLNWQYEEARKRVANIQQQLARLDNESWPSTAE 265
E ++ R ++R +RL Q EE ++ + Q + + E+
Sbjct: 1620 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARR 1679
Query: 266 ADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEERERLEEELRRARATSAQGATER 325
+ Q ++++E QEL+ QR+ A A ++R E+EL R RA + QG +R
Sbjct: 1680 RGKAEEQAVRQRELAEQELE---KQRQLAEGTA---QQRLAAEQELIRLRAETEQGEQQR 1733
Query: 326 ILLQEKRNCLLMQLEEATRLTSYLQSQLKSLCASTLTVSSGSSRGSLASSRGSLASSRGS 385
LL+E+ L + AT+ L+++L + A + + +R SR + S+
Sbjct: 1734 QLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAE-EESRSTSEKSKQR 1792
Query: 386 LSS 388
L +
Sbjct: 1793 LEA 1795
Score = 42.4 bits (98), Expect = 0.002
Identities = 72/388 (18%), Positives = 154/388 (39%), Gaps = 37/388 (9%)
Query: 2 DHINKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLH 61
+ + Q + E+ R E ER L+ + + A EAL + + ++ QQ+ LAQ E ++
Sbjct: 1612 EEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQK-SLAQAEAEKQK 1670
Query: 62 KMCEDDSRSYASSFSGYSTNTKYDPHQIKAE------IASRR----DRLSRLKRELTQMK 111
+ E ++R + + +++ + A +R L RL+ E Q +
Sbjct: 1671 EEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE 1730
Query: 112 QELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSL 171
Q+ Q E+ + LQ + + K E +A ++++R E L+ S
Sbjct: 1731 QQRQLLEEELARLQR-----EAAAATQKRQELEAELAKVRA----------EMEVLLASK 1775
Query: 172 AKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVD- 230
A+ + +++ + ++ +AG ++ + ++ + E + +
Sbjct: 1776 ARAEEESRSTSEKSKQRLE--------AEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1827
Query: 231 --RVRLNWQYEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLII 288
R R + A K A + + + E EA+ +RL+ + E EA +
Sbjct: 1828 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1887
Query: 289 AQRRSAGDVARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSY 348
A + A RL + R+ + EL R + +R ++E+ L E+A +
Sbjct: 1888 AAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAE 1947
Query: 349 LQSQLKSLCASTLTVSSGSSRGSLASSR 376
L+ +L + ++ + L ++R
Sbjct: 1948 LELELGRIRSNAEDTLRSKEQAELEAAR 1975
Score = 42.0 bits (97), Expect = 0.003
Identities = 67/353 (18%), Positives = 142/353 (40%), Gaps = 77/353 (21%)
Query: 9 QIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDS 68
Q+ E+ RRE E +++ L +EA +K + + +R + EE ++L + E +S
Sbjct: 1978 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQES 2036
Query: 69 RSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKG-VETLQEI 127
Q+ E A +R LQ +EK +Q+
Sbjct: 2037 ARQL---------------QLAQEAAQKR----------------LQAEEKAHAFAVQQK 2065
Query: 128 DRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDS 187
++++ T L + Q+++ +LR +A +E + + + +
Sbjct: 2066 EQELQQT-----LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2120
Query: 188 LVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEEARK---- 243
L ++ A +Q E ++R + E AR+
Sbjct: 2121 LKQSA------------EEQAQARAQAQAAAE-----------KLRKEAEQEAARRAQAE 2157
Query: 244 RVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEE 303
+ A Q+Q A + E AE Q +++K + QEL + Q + + +
Sbjct: 2158 QAALRQKQAADAEMEKHKKFAE------QTLRQKAQVEQELTTLRLQ------LEETDHQ 2205
Query: 304 RERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSL 356
+ L+EEL+R +A + + A +R ++E+ + +Q+EE ++L + ++++ ++L
Sbjct: 2206 KNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRAL 2258
Score = 37.7 bits (86), Expect = 0.060
Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 8/132 (6%)
Query: 942 TLERRTLRYKQSCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQ 1001
T +R QS R+S AE A+ LE LQ QL EE + + E A+
Sbjct: 1573 TAQRSAEAELQSKRASFAEKTAQ----LERSLQEEHVAVAQLREEAERRAQQQAEAERAR 1628
Query: 1002 LRGQTDLPPWVLRDERLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRGQSH 1061
+ +L W L+ L +AE +Q L + AEK ++A +E + RG++
Sbjct: 1629 EEAERELERWQLKANEALRLRLQAEEVAQQKSL---AQAEAEKQKEEAEREA-RRRGKAE 1684
Query: 1062 KEPIQVQTFREK 1073
++ ++ + E+
Sbjct: 1685 EQAVRQRELAEQ 1696
Score = 36.2 bits (82), Expect = 0.17
Identities = 84/369 (22%), Positives = 147/369 (39%), Gaps = 51/369 (13%)
Query: 732 EPSRTREAGCAGESSARDPAHTI--SISGKTDAVTVLLARTTAQLQAVER---ELAEERA 786
E +R R+ E R+ + S++ + +A + A L+ VER ++ E R
Sbjct: 1972 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR----QRKAALEEVERLKAKVEEARR 2027
Query: 787 KLEYTEEEV---LEMERKEEQAEAISERSWQADSVDSGCSNCTQTSPPYPEPCCMGIDSI 843
E E+E L++ ++ Q +E A +V QT +D +
Sbjct: 2028 LRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQL 2083
Query: 844 LGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASL---VKERPSRRARGSPFVR 900
G A+A + E+ + + ++ ++E +EEA L +E+ RA+
Sbjct: 2084 RGE---AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2140
Query: 901 SGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVRNTLERRTLRYKQSCRSSLAE 960
Q + A+++ + +D+ K +TLR K L
Sbjct: 2141 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK------FAEQTLRQKAQVEQELTT 2194
Query: 961 LMARTS--------LDLELD-LQASRT---RQR-QLNEELCALRELRQRLEDAQLRGQTD 1007
L + LD EL L+A T RQR Q+ EEL ++R + L + R + +
Sbjct: 2195 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2254
Query: 1008 LPPWVLRDE--RLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRGQSHKEPI 1065
+LRD+ R L EAE K+ E+AA L A++E +LR + ++
Sbjct: 2255 NRALILRDKDNTQRFLQEEAE------KMKQVAEEAAR--LSVAAQEAARLRQLAEEDLA 2306
Query: 1066 QVQTFREKI 1074
Q + EK+
Sbjct: 2307 QQRALAEKM 2315
Score = 33.1 bits (74), Expect = 1.5
Identities = 68/357 (19%), Positives = 139/357 (38%), Gaps = 30/357 (8%)
Query: 717 EMQLRWHSVQVFTSSEPSRTREAGCAGESSARD----PAHTISISGKTDAVTVLLARTTA 772
E+QL + Q+ + P++ + ES ++ H ++ T ++ T
Sbjct: 1287 ELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLR 1346
Query: 773 QLQAVERELAEERAK-LEYTEEEVLEMERKEEQAEAISERSWQADSVDSGCSNCTQTSPP 831
+++ ER ++RA+ E E +E++ + AEA ++ QA+ Q
Sbjct: 1347 RMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ---- 1402
Query: 832 YPEPCCMGIDSILGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASLVKERPSR 891
+ ++ AA Q L+ ++++ ++ + + ER
Sbjct: 1403 ---------EEVVRREEAAVDAQQQKRSIQEE-LQQLRQSSEAEIQAKARQAEAAERSRL 1452
Query: 892 RARGSPFVRSGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVRNTLERRTLRYK 951
R V + ++ GA + R++ ++ R++ L R+
Sbjct: 1453 RIEEEIRVVRLQLEATERQRGGAEGELQALRARAE-EAEAQKRQAQEEAERLRRQVQDES 1511
Query: 952 QSCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQLR-GQTDLPP 1010
Q R + EL +R + E A+R +QR L AL ELR + E+A+ R Q ++
Sbjct: 1512 QRKRQAEVELASRVKAEAE----AAREKQRALQ----ALEELRLQAEEAERRLRQAEVER 1563
Query: 1011 WVLRDERLRGLLREAERQTRQTKLDYRHEQA-AEKMLKKASKEIYQLRGQSHKEPIQ 1066
L R AE + + + + + A E+ L++ + QLR ++ + Q
Sbjct: 1564 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1620
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 57.4 bits (137), Expect = 7e-08
Identities = 78/346 (22%), Positives = 142/346 (41%), Gaps = 40/346 (11%)
Query: 11 EDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRS 70
E+ Q R E+MLKE + QEA K E ++QQ+ ELAQE+ ++L + E ++
Sbjct: 2298 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQK-ELAQEQARRLQEDKEQMAQQ 2356
Query: 71 YASSFSGYSTNTKYDPH---QIKAEIASRRDRLSRLKRELTQMKQELQ-YKEKGVETLQE 126
A G+ + + ++ AE + R++ + R + +++ Q ++++ E ++
Sbjct: 2357 LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2416
Query: 127 IDRKMSSTHTSYKLDEAQAIMSE-----LRTIKKAICTGEKERRDLMHSLAKLTDSFKNS 181
+ R +T L + I + +++AI E+E+ L L +
Sbjct: 2417 LHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2476
Query: 182 CSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLV----DRVRLNWQ 237
+V + + + Q F F+ +K +L D V Q
Sbjct: 2477 QTVQQEQL-------LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ 2529
Query: 238 YEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDV 297
E ++R QQQ+ + S EA R + + + +ELQ + QRR ++
Sbjct: 2530 LREEQQRQ---QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEEL 2586
Query: 298 ARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEAT 343
L EE +RL E+L+ LL+E+ L EE T
Sbjct: 2587 --LAEENQRLREQLQ--------------LLEEQHRAALAHSEEVT 2616
Score = 52.8 bits (125), Expect = 2e-06
Identities = 79/363 (21%), Positives = 152/363 (41%), Gaps = 55/363 (15%)
Query: 34 EALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEI 93
+AL A+ E + ++++ AQEE ++L + +D+S+ Q + E+
Sbjct: 1476 QALRARAEEAEAQKRQ---AQEEAERLRRQVQDESQR---------------KRQAEVEL 1517
Query: 94 ASRRDRLSRLKRELTQMKQELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTI 153
ASR + RE + Q L+ E E +R++ +++ A+ + L T
Sbjct: 1518 ASRVKAEAEAAREKQRALQALEELRLQAE---EAERRLRQA----EVERARQVQVALETA 1570
Query: 154 KKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQ 213
+++ E E + S A+ T + S HV V ++ + +Q
Sbjct: 1571 QRS---AEAELQSKRASFAEKTAQLERSLQ--------EEHVAV----AQLREEAERRAQ 1615
Query: 214 TDIIGEFVFDDKTRLVDR--------VRLNWQYEEARKRVANIQQQLARLDNESWPSTAE 265
E ++ R ++R +RL Q EE ++ + Q + + E+
Sbjct: 1616 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARR 1675
Query: 266 ADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEERERLEEELRRARATSAQGATER 325
+ Q ++++E QEL+ QR+ A A ++R E+EL R RA + QG +R
Sbjct: 1676 RGKAEEQAVRQRELAEQELE---KQRQLAEGTA---QQRLAAEQELIRLRAETEQGEQQR 1729
Query: 326 ILLQEKRNCLLMQLEEATRLTSYLQSQLKSLCASTLTVSSGSSRGSLASSRGSLASSRGS 385
LL+E+ L + AT+ L+++L + A + + +R SR + S+
Sbjct: 1730 QLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAE-EESRSTSEKSKQR 1788
Query: 386 LSS 388
L +
Sbjct: 1789 LEA 1791
Score = 42.4 bits (98), Expect = 0.002
Identities = 72/388 (18%), Positives = 154/388 (39%), Gaps = 37/388 (9%)
Query: 2 DHINKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLH 61
+ + Q + E+ R E ER L+ + + A EAL + + ++ QQ+ LAQ E ++
Sbjct: 1608 EEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQK-SLAQAEAEKQK 1666
Query: 62 KMCEDDSRSYASSFSGYSTNTKYDPHQIKAE------IASRR----DRLSRLKRELTQMK 111
+ E ++R + + +++ + A +R L RL+ E Q +
Sbjct: 1667 EEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE 1726
Query: 112 QELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSL 171
Q+ Q E+ + LQ + + K E +A ++++R E L+ S
Sbjct: 1727 QQRQLLEEELARLQR-----EAAAATQKRQELEAELAKVRA----------EMEVLLASK 1771
Query: 172 AKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVD- 230
A+ + +++ + ++ +AG ++ + ++ + E + +
Sbjct: 1772 ARAEEESRSTSEKSKQRLE--------AEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1823
Query: 231 --RVRLNWQYEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLII 288
R R + A K A + + + E EA+ +RL+ + E EA +
Sbjct: 1824 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1883
Query: 289 AQRRSAGDVARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSY 348
A + A RL + R+ + EL R + +R ++E+ L E+A +
Sbjct: 1884 AAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAE 1943
Query: 349 LQSQLKSLCASTLTVSSGSSRGSLASSR 376
L+ +L + ++ + L ++R
Sbjct: 1944 LELELGRIRSNAEDTLRSKEQAELEAAR 1971
Score = 42.0 bits (97), Expect = 0.003
Identities = 67/353 (18%), Positives = 142/353 (40%), Gaps = 77/353 (21%)
Query: 9 QIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDS 68
Q+ E+ RRE E +++ L +EA +K + + +R + EE ++L + E +S
Sbjct: 1974 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQES 2032
Query: 69 RSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKG-VETLQEI 127
Q+ E A +R LQ +EK +Q+
Sbjct: 2033 ARQL---------------QLAQEAAQKR----------------LQAEEKAHAFAVQQK 2061
Query: 128 DRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDS 187
++++ T L + Q+++ +LR +A +E + + + +
Sbjct: 2062 EQELQQT-----LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2116
Query: 188 LVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEEARK---- 243
L ++ A +Q E ++R + E AR+
Sbjct: 2117 LKQSA------------EEQAQARAQAQAAAE-----------KLRKEAEQEAARRAQAE 2153
Query: 244 RVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEE 303
+ A Q+Q A + E AE Q +++K + QEL + Q + + +
Sbjct: 2154 QAALRQKQAADAEMEKHKKFAE------QTLRQKAQVEQELTTLRLQ------LEETDHQ 2201
Query: 304 RERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSL 356
+ L+EEL+R +A + + A +R ++E+ + +Q+EE ++L + ++++ ++L
Sbjct: 2202 KNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRAL 2254
Score = 37.7 bits (86), Expect = 0.060
Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 8/132 (6%)
Query: 942 TLERRTLRYKQSCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQ 1001
T +R QS R+S AE A+ LE LQ QL EE + + E A+
Sbjct: 1569 TAQRSAEAELQSKRASFAEKTAQ----LERSLQEEHVAVAQLREEAERRAQQQAEAERAR 1624
Query: 1002 LRGQTDLPPWVLRDERLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRGQSH 1061
+ +L W L+ L +AE +Q L + AEK ++A +E + RG++
Sbjct: 1625 EEAERELERWQLKANEALRLRLQAEEVAQQKSL---AQAEAEKQKEEAEREA-RRRGKAE 1680
Query: 1062 KEPIQVQTFREK 1073
++ ++ + E+
Sbjct: 1681 EQAVRQRELAEQ 1692
Score = 36.2 bits (82), Expect = 0.17
Identities = 84/369 (22%), Positives = 147/369 (39%), Gaps = 51/369 (13%)
Query: 732 EPSRTREAGCAGESSARDPAHTI--SISGKTDAVTVLLARTTAQLQAVER---ELAEERA 786
E +R R+ E R+ + S++ + +A + A L+ VER ++ E R
Sbjct: 1968 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR----QRKAALEEVERLKAKVEEARR 2023
Query: 787 KLEYTEEEV---LEMERKEEQAEAISERSWQADSVDSGCSNCTQTSPPYPEPCCMGIDSI 843
E E+E L++ ++ Q +E A +V QT +D +
Sbjct: 2024 LRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQL 2079
Query: 844 LGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASL---VKERPSRRARGSPFVR 900
G A+A + E+ + + ++ ++E +EEA L +E+ RA+
Sbjct: 2080 RGE---AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2136
Query: 901 SGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVRNTLERRTLRYKQSCRSSLAE 960
Q + A+++ + +D+ K +TLR K L
Sbjct: 2137 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK------FAEQTLRQKAQVEQELTT 2190
Query: 961 LMARTS--------LDLELD-LQASRT---RQR-QLNEELCALRELRQRLEDAQLRGQTD 1007
L + LD EL L+A T RQR Q+ EEL ++R + L + R + +
Sbjct: 2191 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2250
Query: 1008 LPPWVLRDE--RLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRGQSHKEPI 1065
+LRD+ R L EAE K+ E+AA L A++E +LR + ++
Sbjct: 2251 NRALILRDKDNTQRFLQEEAE------KMKQVAEEAAR--LSVAAQEAARLRQLAEEDLA 2302
Query: 1066 QVQTFREKI 1074
Q + EK+
Sbjct: 2303 QQRALAEKM 2311
Score = 33.1 bits (74), Expect = 1.5
Identities = 68/357 (19%), Positives = 139/357 (38%), Gaps = 30/357 (8%)
Query: 717 EMQLRWHSVQVFTSSEPSRTREAGCAGESSARD----PAHTISISGKTDAVTVLLARTTA 772
E+QL + Q+ + P++ + ES ++ H ++ T ++ T
Sbjct: 1283 ELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLR 1342
Query: 773 QLQAVERELAEERAK-LEYTEEEVLEMERKEEQAEAISERSWQADSVDSGCSNCTQTSPP 831
+++ ER ++RA+ E E +E++ + AEA ++ QA+ Q
Sbjct: 1343 RMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ---- 1398
Query: 832 YPEPCCMGIDSILGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASLVKERPSR 891
+ ++ AA Q L+ ++++ ++ + + ER
Sbjct: 1399 ---------EEVVRREEAAVDAQQQKRSIQEE-LQQLRQSSEAEIQAKARQAEAAERSRL 1448
Query: 892 RARGSPFVRSGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVRNTLERRTLRYK 951
R V + ++ GA + R++ ++ R++ L R+
Sbjct: 1449 RIEEEIRVVRLQLEATERQRGGAEGELQALRARAE-EAEAQKRQAQEEAERLRRQVQDES 1507
Query: 952 QSCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQLR-GQTDLPP 1010
Q R + EL +R + E A+R +QR L AL ELR + E+A+ R Q ++
Sbjct: 1508 QRKRQAEVELASRVKAEAE----AAREKQRALQ----ALEELRLQAEEAERRLRQAEVER 1559
Query: 1011 WVLRDERLRGLLREAERQTRQTKLDYRHEQA-AEKMLKKASKEIYQLRGQSHKEPIQ 1066
L R AE + + + + + A E+ L++ + QLR ++ + Q
Sbjct: 1560 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1616
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 57.4 bits (137), Expect = 7e-08
Identities = 78/346 (22%), Positives = 142/346 (41%), Gaps = 40/346 (11%)
Query: 11 EDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRS 70
E+ Q R E+MLKE + QEA K E ++QQ+ ELAQE+ ++L + E ++
Sbjct: 2266 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQK-ELAQEQARRLQEDKEQMAQQ 2324
Query: 71 YASSFSGYSTNTKYDPH---QIKAEIASRRDRLSRLKRELTQMKQELQ-YKEKGVETLQE 126
A G+ + + ++ AE + R++ + R + +++ Q ++++ E ++
Sbjct: 2325 LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2384
Query: 127 IDRKMSSTHTSYKLDEAQAIMSE-----LRTIKKAICTGEKERRDLMHSLAKLTDSFKNS 181
+ R +T L + I + +++AI E+E+ L L +
Sbjct: 2385 LHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2444
Query: 182 CSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLV----DRVRLNWQ 237
+V + + + Q F F+ +K +L D V Q
Sbjct: 2445 QTVQQEQL-------LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ 2497
Query: 238 YEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDV 297
E ++R QQQ+ + S EA R + + + +ELQ + QRR ++
Sbjct: 2498 LREEQQRQ---QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEEL 2554
Query: 298 ARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEAT 343
L EE +RL E+L+ LL+E+ L EE T
Sbjct: 2555 --LAEENQRLREQLQ--------------LLEEQHRAALAHSEEVT 2584
Score = 52.8 bits (125), Expect = 2e-06
Identities = 79/363 (21%), Positives = 152/363 (41%), Gaps = 55/363 (15%)
Query: 34 EALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEI 93
+AL A+ E + ++++ AQEE ++L + +D+S+ Q + E+
Sbjct: 1444 QALRARAEEAEAQKRQ---AQEEAERLRRQVQDESQR---------------KRQAEVEL 1485
Query: 94 ASRRDRLSRLKRELTQMKQELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTI 153
ASR + RE + Q L+ E E +R++ +++ A+ + L T
Sbjct: 1486 ASRVKAEAEAAREKQRALQALEELRLQAE---EAERRLRQA----EVERARQVQVALETA 1538
Query: 154 KKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQ 213
+++ E E + S A+ T + S HV V ++ + +Q
Sbjct: 1539 QRS---AEAELQSKRASFAEKTAQLERSLQ--------EEHVAV----AQLREEAERRAQ 1583
Query: 214 TDIIGEFVFDDKTRLVDR--------VRLNWQYEEARKRVANIQQQLARLDNESWPSTAE 265
E ++ R ++R +RL Q EE ++ + Q + + E+
Sbjct: 1584 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARR 1643
Query: 266 ADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEERERLEEELRRARATSAQGATER 325
+ Q ++++E QEL+ QR+ A A ++R E+EL R RA + QG +R
Sbjct: 1644 RGKAEEQAVRQRELAEQELE---KQRQLAEGTA---QQRLAAEQELIRLRAETEQGEQQR 1697
Query: 326 ILLQEKRNCLLMQLEEATRLTSYLQSQLKSLCASTLTVSSGSSRGSLASSRGSLASSRGS 385
LL+E+ L + AT+ L+++L + A + + +R SR + S+
Sbjct: 1698 QLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAE-EESRSTSEKSKQR 1756
Query: 386 LSS 388
L +
Sbjct: 1757 LEA 1759
Score = 42.4 bits (98), Expect = 0.002
Identities = 72/388 (18%), Positives = 154/388 (39%), Gaps = 37/388 (9%)
Query: 2 DHINKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLH 61
+ + Q + E+ R E ER L+ + + A EAL + + ++ QQ+ LAQ E ++
Sbjct: 1576 EEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQK-SLAQAEAEKQK 1634
Query: 62 KMCEDDSRSYASSFSGYSTNTKYDPHQIKAE------IASRR----DRLSRLKRELTQMK 111
+ E ++R + + +++ + A +R L RL+ E Q +
Sbjct: 1635 EEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE 1694
Query: 112 QELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSL 171
Q+ Q E+ + LQ + + K E +A ++++R E L+ S
Sbjct: 1695 QQRQLLEEELARLQR-----EAAAATQKRQELEAELAKVRA----------EMEVLLASK 1739
Query: 172 AKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVD- 230
A+ + +++ + ++ +AG ++ + ++ + E + +
Sbjct: 1740 ARAEEESRSTSEKSKQRLE--------AEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1791
Query: 231 --RVRLNWQYEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLII 288
R R + A K A + + + E EA+ +RL+ + E EA +
Sbjct: 1792 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1851
Query: 289 AQRRSAGDVARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSY 348
A + A RL + R+ + EL R + +R ++E+ L E+A +
Sbjct: 1852 AAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAE 1911
Query: 349 LQSQLKSLCASTLTVSSGSSRGSLASSR 376
L+ +L + ++ + L ++R
Sbjct: 1912 LELELGRIRSNAEDTLRSKEQAELEAAR 1939
Score = 42.0 bits (97), Expect = 0.003
Identities = 67/353 (18%), Positives = 142/353 (40%), Gaps = 77/353 (21%)
Query: 9 QIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDS 68
Q+ E+ RRE E +++ L +EA +K + + +R + EE ++L + E +S
Sbjct: 1942 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQES 2000
Query: 69 RSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKG-VETLQEI 127
Q+ E A +R LQ +EK +Q+
Sbjct: 2001 ARQL---------------QLAQEAAQKR----------------LQAEEKAHAFAVQQK 2029
Query: 128 DRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDS 187
++++ T L + Q+++ +LR +A +E + + + +
Sbjct: 2030 EQELQQT-----LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2084
Query: 188 LVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEEARK---- 243
L ++ A +Q E ++R + E AR+
Sbjct: 2085 LKQSA------------EEQAQARAQAQAAAE-----------KLRKEAEQEAARRAQAE 2121
Query: 244 RVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEE 303
+ A Q+Q A + E AE Q +++K + QEL + Q + + +
Sbjct: 2122 QAALRQKQAADAEMEKHKKFAE------QTLRQKAQVEQELTTLRLQ------LEETDHQ 2169
Query: 304 RERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSL 356
+ L+EEL+R +A + + A +R ++E+ + +Q+EE ++L + ++++ ++L
Sbjct: 2170 KNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRAL 2222
Score = 37.7 bits (86), Expect = 0.060
Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 8/132 (6%)
Query: 942 TLERRTLRYKQSCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQ 1001
T +R QS R+S AE A+ LE LQ QL EE + + E A+
Sbjct: 1537 TAQRSAEAELQSKRASFAEKTAQ----LERSLQEEHVAVAQLREEAERRAQQQAEAERAR 1592
Query: 1002 LRGQTDLPPWVLRDERLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRGQSH 1061
+ +L W L+ L +AE +Q L + AEK ++A +E + RG++
Sbjct: 1593 EEAERELERWQLKANEALRLRLQAEEVAQQKSL---AQAEAEKQKEEAEREA-RRRGKAE 1648
Query: 1062 KEPIQVQTFREK 1073
++ ++ + E+
Sbjct: 1649 EQAVRQRELAEQ 1660
Score = 36.2 bits (82), Expect = 0.17
Identities = 84/369 (22%), Positives = 147/369 (39%), Gaps = 51/369 (13%)
Query: 732 EPSRTREAGCAGESSARDPAHTI--SISGKTDAVTVLLARTTAQLQAVER---ELAEERA 786
E +R R+ E R+ + S++ + +A + A L+ VER ++ E R
Sbjct: 1936 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR----QRKAALEEVERLKAKVEEARR 1991
Query: 787 KLEYTEEEV---LEMERKEEQAEAISERSWQADSVDSGCSNCTQTSPPYPEPCCMGIDSI 843
E E+E L++ ++ Q +E A +V QT +D +
Sbjct: 1992 LRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQL 2047
Query: 844 LGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASL---VKERPSRRARGSPFVR 900
G A+A + E+ + + ++ ++E +EEA L +E+ RA+
Sbjct: 2048 RGE---AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2104
Query: 901 SGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVRNTLERRTLRYKQSCRSSLAE 960
Q + A+++ + +D+ K +TLR K L
Sbjct: 2105 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK------FAEQTLRQKAQVEQELTT 2158
Query: 961 LMARTS--------LDLELD-LQASRT---RQR-QLNEELCALRELRQRLEDAQLRGQTD 1007
L + LD EL L+A T RQR Q+ EEL ++R + L + R + +
Sbjct: 2159 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2218
Query: 1008 LPPWVLRDE--RLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRGQSHKEPI 1065
+LRD+ R L EAE K+ E+AA L A++E +LR + ++
Sbjct: 2219 NRALILRDKDNTQRFLQEEAE------KMKQVAEEAAR--LSVAAQEAARLRQLAEEDLA 2270
Query: 1066 QVQTFREKI 1074
Q + EK+
Sbjct: 2271 QQRALAEKM 2279
Score = 33.1 bits (74), Expect = 1.5
Identities = 68/357 (19%), Positives = 139/357 (38%), Gaps = 30/357 (8%)
Query: 717 EMQLRWHSVQVFTSSEPSRTREAGCAGESSARD----PAHTISISGKTDAVTVLLARTTA 772
E+QL + Q+ + P++ + ES ++ H ++ T ++ T
Sbjct: 1251 ELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLR 1310
Query: 773 QLQAVERELAEERAK-LEYTEEEVLEMERKEEQAEAISERSWQADSVDSGCSNCTQTSPP 831
+++ ER ++RA+ E E +E++ + AEA ++ QA+ Q
Sbjct: 1311 RMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ---- 1366
Query: 832 YPEPCCMGIDSILGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASLVKERPSR 891
+ ++ AA Q L+ ++++ ++ + + ER
Sbjct: 1367 ---------EEVVRREEAAVDAQQQKRSIQEE-LQQLRQSSEAEIQAKARQAEAAERSRL 1416
Query: 892 RARGSPFVRSGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVRNTLERRTLRYK 951
R V + ++ GA + R++ ++ R++ L R+
Sbjct: 1417 RIEEEIRVVRLQLEATERQRGGAEGELQALRARAE-EAEAQKRQAQEEAERLRRQVQDES 1475
Query: 952 QSCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQLR-GQTDLPP 1010
Q R + EL +R + E A+R +QR L AL ELR + E+A+ R Q ++
Sbjct: 1476 QRKRQAEVELASRVKAEAE----AAREKQRALQ----ALEELRLQAEEAERRLRQAEVER 1527
Query: 1011 WVLRDERLRGLLREAERQTRQTKLDYRHEQA-AEKMLKKASKEIYQLRGQSHKEPIQ 1066
L R AE + + + + + A E+ L++ + QLR ++ + Q
Sbjct: 1528 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1584
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 57.4 bits (137), Expect = 7e-08
Identities = 78/346 (22%), Positives = 142/346 (41%), Gaps = 40/346 (11%)
Query: 11 EDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRS 70
E+ Q R E+MLKE + QEA K E ++QQ+ ELAQE+ ++L + E ++
Sbjct: 2435 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQK-ELAQEQARRLQEDKEQMAQQ 2493
Query: 71 YASSFSGYSTNTKYDPH---QIKAEIASRRDRLSRLKRELTQMKQELQ-YKEKGVETLQE 126
A G+ + + ++ AE + R++ + R + +++ Q ++++ E ++
Sbjct: 2494 LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2553
Query: 127 IDRKMSSTHTSYKLDEAQAIMSE-----LRTIKKAICTGEKERRDLMHSLAKLTDSFKNS 181
+ R +T L + I + +++AI E+E+ L L +
Sbjct: 2554 LHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2613
Query: 182 CSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLV----DRVRLNWQ 237
+V + + + Q F F+ +K +L D V Q
Sbjct: 2614 QTVQQEQL-------LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ 2666
Query: 238 YEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDV 297
E ++R QQQ+ + S EA R + + + +ELQ + QRR ++
Sbjct: 2667 LREEQQRQ---QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEEL 2723
Query: 298 ARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEAT 343
L EE +RL E+L+ LL+E+ L EE T
Sbjct: 2724 --LAEENQRLREQLQ--------------LLEEQHRAALAHSEEVT 2753
Score = 52.8 bits (125), Expect = 2e-06
Identities = 79/363 (21%), Positives = 152/363 (41%), Gaps = 55/363 (15%)
Query: 34 EALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEI 93
+AL A+ E + ++++ AQEE ++L + +D+S+ Q + E+
Sbjct: 1613 QALRARAEEAEAQKRQ---AQEEAERLRRQVQDESQR---------------KRQAEVEL 1654
Query: 94 ASRRDRLSRLKRELTQMKQELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTI 153
ASR + RE + Q L+ E E +R++ +++ A+ + L T
Sbjct: 1655 ASRVKAEAEAAREKQRALQALEELRLQAE---EAERRLRQA----EVERARQVQVALETA 1707
Query: 154 KKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQ 213
+++ E E + S A+ T + S HV V ++ + +Q
Sbjct: 1708 QRS---AEAELQSKRASFAEKTAQLERSLQ--------EEHVAV----AQLREEAERRAQ 1752
Query: 214 TDIIGEFVFDDKTRLVDR--------VRLNWQYEEARKRVANIQQQLARLDNESWPSTAE 265
E ++ R ++R +RL Q EE ++ + Q + + E+
Sbjct: 1753 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARR 1812
Query: 266 ADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEERERLEEELRRARATSAQGATER 325
+ Q ++++E QEL+ QR+ A A ++R E+EL R RA + QG +R
Sbjct: 1813 RGKAEEQAVRQRELAEQELE---KQRQLAEGTA---QQRLAAEQELIRLRAETEQGEQQR 1866
Query: 326 ILLQEKRNCLLMQLEEATRLTSYLQSQLKSLCASTLTVSSGSSRGSLASSRGSLASSRGS 385
LL+E+ L + AT+ L+++L + A + + +R SR + S+
Sbjct: 1867 QLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAE-EESRSTSEKSKQR 1925
Query: 386 LSS 388
L +
Sbjct: 1926 LEA 1928
Score = 42.4 bits (98), Expect = 0.002
Identities = 72/388 (18%), Positives = 154/388 (39%), Gaps = 37/388 (9%)
Query: 2 DHINKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLH 61
+ + Q + E+ R E ER L+ + + A EAL + + ++ QQ+ LAQ E ++
Sbjct: 1745 EEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQK-SLAQAEAEKQK 1803
Query: 62 KMCEDDSRSYASSFSGYSTNTKYDPHQIKAE------IASRR----DRLSRLKRELTQMK 111
+ E ++R + + +++ + A +R L RL+ E Q +
Sbjct: 1804 EEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE 1863
Query: 112 QELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSL 171
Q+ Q E+ + LQ + + K E +A ++++R E L+ S
Sbjct: 1864 QQRQLLEEELARLQR-----EAAAATQKRQELEAELAKVRA----------EMEVLLASK 1908
Query: 172 AKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVD- 230
A+ + +++ + ++ +AG ++ + ++ + E + +
Sbjct: 1909 ARAEEESRSTSEKSKQRLE--------AEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1960
Query: 231 --RVRLNWQYEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLII 288
R R + A K A + + + E EA+ +RL+ + E EA +
Sbjct: 1961 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 2020
Query: 289 AQRRSAGDVARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSY 348
A + A RL + R+ + EL R + +R ++E+ L E+A +
Sbjct: 2021 AAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAE 2080
Query: 349 LQSQLKSLCASTLTVSSGSSRGSLASSR 376
L+ +L + ++ + L ++R
Sbjct: 2081 LELELGRIRSNAEDTLRSKEQAELEAAR 2108
Score = 42.0 bits (97), Expect = 0.003
Identities = 67/353 (18%), Positives = 142/353 (40%), Gaps = 77/353 (21%)
Query: 9 QIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDS 68
Q+ E+ RRE E +++ L +EA +K + + +R + EE ++L + E +S
Sbjct: 2111 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQES 2169
Query: 69 RSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKG-VETLQEI 127
Q+ E A +R LQ +EK +Q+
Sbjct: 2170 ARQL---------------QLAQEAAQKR----------------LQAEEKAHAFAVQQK 2198
Query: 128 DRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDS 187
++++ T L + Q+++ +LR +A +E + + + +
Sbjct: 2199 EQELQQT-----LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2253
Query: 188 LVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEEARK---- 243
L ++ A +Q E ++R + E AR+
Sbjct: 2254 LKQSA------------EEQAQARAQAQAAAE-----------KLRKEAEQEAARRAQAE 2290
Query: 244 RVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEE 303
+ A Q+Q A + E AE Q +++K + QEL + Q + + +
Sbjct: 2291 QAALRQKQAADAEMEKHKKFAE------QTLRQKAQVEQELTTLRLQ------LEETDHQ 2338
Query: 304 RERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSL 356
+ L+EEL+R +A + + A +R ++E+ + +Q+EE ++L + ++++ ++L
Sbjct: 2339 KNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRAL 2391
Score = 37.7 bits (86), Expect = 0.060
Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 8/132 (6%)
Query: 942 TLERRTLRYKQSCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQ 1001
T +R QS R+S AE A+ LE LQ QL EE + + E A+
Sbjct: 1706 TAQRSAEAELQSKRASFAEKTAQ----LERSLQEEHVAVAQLREEAERRAQQQAEAERAR 1761
Query: 1002 LRGQTDLPPWVLRDERLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRGQSH 1061
+ +L W L+ L +AE +Q L + AEK ++A +E + RG++
Sbjct: 1762 EEAERELERWQLKANEALRLRLQAEEVAQQKSL---AQAEAEKQKEEAEREA-RRRGKAE 1817
Query: 1062 KEPIQVQTFREK 1073
++ ++ + E+
Sbjct: 1818 EQAVRQRELAEQ 1829
Score = 36.2 bits (82), Expect = 0.17
Identities = 84/369 (22%), Positives = 147/369 (39%), Gaps = 51/369 (13%)
Query: 732 EPSRTREAGCAGESSARDPAHTI--SISGKTDAVTVLLARTTAQLQAVER---ELAEERA 786
E +R R+ E R+ + S++ + +A + A L+ VER ++ E R
Sbjct: 2105 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR----QRKAALEEVERLKAKVEEARR 2160
Query: 787 KLEYTEEEV---LEMERKEEQAEAISERSWQADSVDSGCSNCTQTSPPYPEPCCMGIDSI 843
E E+E L++ ++ Q +E A +V QT +D +
Sbjct: 2161 LRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQL 2216
Query: 844 LGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASL---VKERPSRRARGSPFVR 900
G A+A + E+ + + ++ ++E +EEA L +E+ RA+
Sbjct: 2217 RGE---AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2273
Query: 901 SGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVRNTLERRTLRYKQSCRSSLAE 960
Q + A+++ + +D+ K +TLR K L
Sbjct: 2274 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK------FAEQTLRQKAQVEQELTT 2327
Query: 961 LMARTS--------LDLELD-LQASRT---RQR-QLNEELCALRELRQRLEDAQLRGQTD 1007
L + LD EL L+A T RQR Q+ EEL ++R + L + R + +
Sbjct: 2328 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2387
Query: 1008 LPPWVLRDE--RLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRGQSHKEPI 1065
+LRD+ R L EAE K+ E+AA L A++E +LR + ++
Sbjct: 2388 NRALILRDKDNTQRFLQEEAE------KMKQVAEEAAR--LSVAAQEAARLRQLAEEDLA 2439
Query: 1066 QVQTFREKI 1074
Q + EK+
Sbjct: 2440 QQRALAEKM 2448
Score = 33.1 bits (74), Expect = 1.5
Identities = 68/357 (19%), Positives = 139/357 (38%), Gaps = 30/357 (8%)
Query: 717 EMQLRWHSVQVFTSSEPSRTREAGCAGESSARD----PAHTISISGKTDAVTVLLARTTA 772
E+QL + Q+ + P++ + ES ++ H ++ T ++ T
Sbjct: 1420 ELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLR 1479
Query: 773 QLQAVERELAEERAK-LEYTEEEVLEMERKEEQAEAISERSWQADSVDSGCSNCTQTSPP 831
+++ ER ++RA+ E E +E++ + AEA ++ QA+ Q
Sbjct: 1480 RMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ---- 1535
Query: 832 YPEPCCMGIDSILGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASLVKERPSR 891
+ ++ AA Q L+ ++++ ++ + + ER
Sbjct: 1536 ---------EEVVRREEAAVDAQQQKRSIQEE-LQQLRQSSEAEIQAKARQAEAAERSRL 1585
Query: 892 RARGSPFVRSGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVRNTLERRTLRYK 951
R V + ++ GA + R++ ++ R++ L R+
Sbjct: 1586 RIEEEIRVVRLQLEATERQRGGAEGELQALRARAE-EAEAQKRQAQEEAERLRRQVQDES 1644
Query: 952 QSCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQLR-GQTDLPP 1010
Q R + EL +R + E A+R +QR L AL ELR + E+A+ R Q ++
Sbjct: 1645 QRKRQAEVELASRVKAEAE----AAREKQRALQ----ALEELRLQAEEAERRLRQAEVER 1696
Query: 1011 WVLRDERLRGLLREAERQTRQTKLDYRHEQA-AEKMLKKASKEIYQLRGQSHKEPIQ 1066
L R AE + + + + + A E+ L++ + QLR ++ + Q
Sbjct: 1697 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1753
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 57.4 bits (137), Expect = 7e-08
Identities = 78/346 (22%), Positives = 142/346 (41%), Gaps = 40/346 (11%)
Query: 11 EDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRS 70
E+ Q R E+MLKE + QEA K E ++QQ+ ELAQE+ ++L + E ++
Sbjct: 2276 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQK-ELAQEQARRLQEDKEQMAQQ 2334
Query: 71 YASSFSGYSTNTKYDPH---QIKAEIASRRDRLSRLKRELTQMKQELQ-YKEKGVETLQE 126
A G+ + + ++ AE + R++ + R + +++ Q ++++ E ++
Sbjct: 2335 LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2394
Query: 127 IDRKMSSTHTSYKLDEAQAIMSE-----LRTIKKAICTGEKERRDLMHSLAKLTDSFKNS 181
+ R +T L + I + +++AI E+E+ L L +
Sbjct: 2395 LHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2454
Query: 182 CSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLV----DRVRLNWQ 237
+V + + + Q F F+ +K +L D V Q
Sbjct: 2455 QTVQQEQL-------LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ 2507
Query: 238 YEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDV 297
E ++R QQQ+ + S EA R + + + +ELQ + QRR ++
Sbjct: 2508 LREEQQRQ---QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEEL 2564
Query: 298 ARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEAT 343
L EE +RL E+L+ LL+E+ L EE T
Sbjct: 2565 --LAEENQRLREQLQ--------------LLEEQHRAALAHSEEVT 2594
Score = 52.8 bits (125), Expect = 2e-06
Identities = 79/363 (21%), Positives = 152/363 (41%), Gaps = 55/363 (15%)
Query: 34 EALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEI 93
+AL A+ E + ++++ AQEE ++L + +D+S+ Q + E+
Sbjct: 1454 QALRARAEEAEAQKRQ---AQEEAERLRRQVQDESQR---------------KRQAEVEL 1495
Query: 94 ASRRDRLSRLKRELTQMKQELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTI 153
ASR + RE + Q L+ E E +R++ +++ A+ + L T
Sbjct: 1496 ASRVKAEAEAAREKQRALQALEELRLQAE---EAERRLRQA----EVERARQVQVALETA 1548
Query: 154 KKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQ 213
+++ E E + S A+ T + S HV V ++ + +Q
Sbjct: 1549 QRS---AEAELQSKRASFAEKTAQLERSLQ--------EEHVAV----AQLREEAERRAQ 1593
Query: 214 TDIIGEFVFDDKTRLVDR--------VRLNWQYEEARKRVANIQQQLARLDNESWPSTAE 265
E ++ R ++R +RL Q EE ++ + Q + + E+
Sbjct: 1594 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARR 1653
Query: 266 ADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEERERLEEELRRARATSAQGATER 325
+ Q ++++E QEL+ QR+ A A ++R E+EL R RA + QG +R
Sbjct: 1654 RGKAEEQAVRQRELAEQELE---KQRQLAEGTA---QQRLAAEQELIRLRAETEQGEQQR 1707
Query: 326 ILLQEKRNCLLMQLEEATRLTSYLQSQLKSLCASTLTVSSGSSRGSLASSRGSLASSRGS 385
LL+E+ L + AT+ L+++L + A + + +R SR + S+
Sbjct: 1708 QLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAE-EESRSTSEKSKQR 1766
Query: 386 LSS 388
L +
Sbjct: 1767 LEA 1769
Score = 42.4 bits (98), Expect = 0.002
Identities = 72/388 (18%), Positives = 154/388 (39%), Gaps = 37/388 (9%)
Query: 2 DHINKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLH 61
+ + Q + E+ R E ER L+ + + A EAL + + ++ QQ+ LAQ E ++
Sbjct: 1586 EEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQK-SLAQAEAEKQK 1644
Query: 62 KMCEDDSRSYASSFSGYSTNTKYDPHQIKAE------IASRR----DRLSRLKRELTQMK 111
+ E ++R + + +++ + A +R L RL+ E Q +
Sbjct: 1645 EEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE 1704
Query: 112 QELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSL 171
Q+ Q E+ + LQ + + K E +A ++++R E L+ S
Sbjct: 1705 QQRQLLEEELARLQR-----EAAAATQKRQELEAELAKVRA----------EMEVLLASK 1749
Query: 172 AKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVD- 230
A+ + +++ + ++ +AG ++ + ++ + E + +
Sbjct: 1750 ARAEEESRSTSEKSKQRLE--------AEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1801
Query: 231 --RVRLNWQYEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLII 288
R R + A K A + + + E EA+ +RL+ + E EA +
Sbjct: 1802 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1861
Query: 289 AQRRSAGDVARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSY 348
A + A RL + R+ + EL R + +R ++E+ L E+A +
Sbjct: 1862 AAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAE 1921
Query: 349 LQSQLKSLCASTLTVSSGSSRGSLASSR 376
L+ +L + ++ + L ++R
Sbjct: 1922 LELELGRIRSNAEDTLRSKEQAELEAAR 1949
Score = 42.0 bits (97), Expect = 0.003
Identities = 67/353 (18%), Positives = 142/353 (40%), Gaps = 77/353 (21%)
Query: 9 QIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDS 68
Q+ E+ RRE E +++ L +EA +K + + +R + EE ++L + E +S
Sbjct: 1952 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQES 2010
Query: 69 RSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKG-VETLQEI 127
Q+ E A +R LQ +EK +Q+
Sbjct: 2011 ARQL---------------QLAQEAAQKR----------------LQAEEKAHAFAVQQK 2039
Query: 128 DRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDS 187
++++ T L + Q+++ +LR +A +E + + + +
Sbjct: 2040 EQELQQT-----LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2094
Query: 188 LVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEEARK---- 243
L ++ A +Q E ++R + E AR+
Sbjct: 2095 LKQSA------------EEQAQARAQAQAAAE-----------KLRKEAEQEAARRAQAE 2131
Query: 244 RVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEE 303
+ A Q+Q A + E AE Q +++K + QEL + Q + + +
Sbjct: 2132 QAALRQKQAADAEMEKHKKFAE------QTLRQKAQVEQELTTLRLQ------LEETDHQ 2179
Query: 304 RERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSL 356
+ L+EEL+R +A + + A +R ++E+ + +Q+EE ++L + ++++ ++L
Sbjct: 2180 KNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRAL 2232
Score = 37.7 bits (86), Expect = 0.060
Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 8/132 (6%)
Query: 942 TLERRTLRYKQSCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQ 1001
T +R QS R+S AE A+ LE LQ QL EE + + E A+
Sbjct: 1547 TAQRSAEAELQSKRASFAEKTAQ----LERSLQEEHVAVAQLREEAERRAQQQAEAERAR 1602
Query: 1002 LRGQTDLPPWVLRDERLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRGQSH 1061
+ +L W L+ L +AE +Q L + AEK ++A +E + RG++
Sbjct: 1603 EEAERELERWQLKANEALRLRLQAEEVAQQKSL---AQAEAEKQKEEAEREA-RRRGKAE 1658
Query: 1062 KEPIQVQTFREK 1073
++ ++ + E+
Sbjct: 1659 EQAVRQRELAEQ 1670
Score = 36.2 bits (82), Expect = 0.17
Identities = 84/369 (22%), Positives = 147/369 (39%), Gaps = 51/369 (13%)
Query: 732 EPSRTREAGCAGESSARDPAHTI--SISGKTDAVTVLLARTTAQLQAVER---ELAEERA 786
E +R R+ E R+ + S++ + +A + A L+ VER ++ E R
Sbjct: 1946 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR----QRKAALEEVERLKAKVEEARR 2001
Query: 787 KLEYTEEEV---LEMERKEEQAEAISERSWQADSVDSGCSNCTQTSPPYPEPCCMGIDSI 843
E E+E L++ ++ Q +E A +V QT +D +
Sbjct: 2002 LRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQL 2057
Query: 844 LGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASL---VKERPSRRARGSPFVR 900
G A+A + E+ + + ++ ++E +EEA L +E+ RA+
Sbjct: 2058 RGE---AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2114
Query: 901 SGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVRNTLERRTLRYKQSCRSSLAE 960
Q + A+++ + +D+ K +TLR K L
Sbjct: 2115 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK------FAEQTLRQKAQVEQELTT 2168
Query: 961 LMARTS--------LDLELD-LQASRT---RQR-QLNEELCALRELRQRLEDAQLRGQTD 1007
L + LD EL L+A T RQR Q+ EEL ++R + L + R + +
Sbjct: 2169 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2228
Query: 1008 LPPWVLRDE--RLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRGQSHKEPI 1065
+LRD+ R L EAE K+ E+AA L A++E +LR + ++
Sbjct: 2229 NRALILRDKDNTQRFLQEEAE------KMKQVAEEAAR--LSVAAQEAARLRQLAEEDLA 2280
Query: 1066 QVQTFREKI 1074
Q + EK+
Sbjct: 2281 QQRALAEKM 2289
Score = 33.1 bits (74), Expect = 1.5
Identities = 68/357 (19%), Positives = 139/357 (38%), Gaps = 30/357 (8%)
Query: 717 EMQLRWHSVQVFTSSEPSRTREAGCAGESSARD----PAHTISISGKTDAVTVLLARTTA 772
E+QL + Q+ + P++ + ES ++ H ++ T ++ T
Sbjct: 1261 ELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLR 1320
Query: 773 QLQAVERELAEERAK-LEYTEEEVLEMERKEEQAEAISERSWQADSVDSGCSNCTQTSPP 831
+++ ER ++RA+ E E +E++ + AEA ++ QA+ Q
Sbjct: 1321 RMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ---- 1376
Query: 832 YPEPCCMGIDSILGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASLVKERPSR 891
+ ++ AA Q L+ ++++ ++ + + ER
Sbjct: 1377 ---------EEVVRREEAAVDAQQQKRSIQEE-LQQLRQSSEAEIQAKARQAEAAERSRL 1426
Query: 892 RARGSPFVRSGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVRNTLERRTLRYK 951
R V + ++ GA + R++ ++ R++ L R+
Sbjct: 1427 RIEEEIRVVRLQLEATERQRGGAEGELQALRARAE-EAEAQKRQAQEEAERLRRQVQDES 1485
Query: 952 QSCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQLR-GQTDLPP 1010
Q R + EL +R + E A+R +QR L AL ELR + E+A+ R Q ++
Sbjct: 1486 QRKRQAEVELASRVKAEAE----AAREKQRALQ----ALEELRLQAEEAERRLRQAEVER 1537
Query: 1011 WVLRDERLRGLLREAERQTRQTKLDYRHEQA-AEKMLKKASKEIYQLRGQSHKEPIQ 1066
L R AE + + + + + A E+ L++ + QLR ++ + Q
Sbjct: 1538 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1594
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 57.4 bits (137), Expect = 7e-08
Identities = 78/346 (22%), Positives = 142/346 (41%), Gaps = 40/346 (11%)
Query: 11 EDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRS 70
E+ Q R E+MLKE + QEA K E ++QQ+ ELAQE+ ++L + E ++
Sbjct: 2284 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQK-ELAQEQARRLQEDKEQMAQQ 2342
Query: 71 YASSFSGYSTNTKYDPH---QIKAEIASRRDRLSRLKRELTQMKQELQ-YKEKGVETLQE 126
A G+ + + ++ AE + R++ + R + +++ Q ++++ E ++
Sbjct: 2343 LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2402
Query: 127 IDRKMSSTHTSYKLDEAQAIMSE-----LRTIKKAICTGEKERRDLMHSLAKLTDSFKNS 181
+ R +T L + I + +++AI E+E+ L L +
Sbjct: 2403 LHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2462
Query: 182 CSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLV----DRVRLNWQ 237
+V + + + Q F F+ +K +L D V Q
Sbjct: 2463 QTVQQEQL-------LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ 2515
Query: 238 YEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDV 297
E ++R QQQ+ + S EA R + + + +ELQ + QRR ++
Sbjct: 2516 LREEQQRQ---QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEEL 2572
Query: 298 ARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEAT 343
L EE +RL E+L+ LL+E+ L EE T
Sbjct: 2573 --LAEENQRLREQLQ--------------LLEEQHRAALAHSEEVT 2602
Score = 52.8 bits (125), Expect = 2e-06
Identities = 79/363 (21%), Positives = 152/363 (41%), Gaps = 55/363 (15%)
Query: 34 EALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEI 93
+AL A+ E + ++++ AQEE ++L + +D+S+ Q + E+
Sbjct: 1462 QALRARAEEAEAQKRQ---AQEEAERLRRQVQDESQR---------------KRQAEVEL 1503
Query: 94 ASRRDRLSRLKRELTQMKQELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTI 153
ASR + RE + Q L+ E E +R++ +++ A+ + L T
Sbjct: 1504 ASRVKAEAEAAREKQRALQALEELRLQAE---EAERRLRQA----EVERARQVQVALETA 1556
Query: 154 KKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQ 213
+++ E E + S A+ T + S HV V ++ + +Q
Sbjct: 1557 QRS---AEAELQSKRASFAEKTAQLERSLQ--------EEHVAV----AQLREEAERRAQ 1601
Query: 214 TDIIGEFVFDDKTRLVDR--------VRLNWQYEEARKRVANIQQQLARLDNESWPSTAE 265
E ++ R ++R +RL Q EE ++ + Q + + E+
Sbjct: 1602 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARR 1661
Query: 266 ADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEERERLEEELRRARATSAQGATER 325
+ Q ++++E QEL+ QR+ A A ++R E+EL R RA + QG +R
Sbjct: 1662 RGKAEEQAVRQRELAEQELE---KQRQLAEGTA---QQRLAAEQELIRLRAETEQGEQQR 1715
Query: 326 ILLQEKRNCLLMQLEEATRLTSYLQSQLKSLCASTLTVSSGSSRGSLASSRGSLASSRGS 385
LL+E+ L + AT+ L+++L + A + + +R SR + S+
Sbjct: 1716 QLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAE-EESRSTSEKSKQR 1774
Query: 386 LSS 388
L +
Sbjct: 1775 LEA 1777
Score = 42.4 bits (98), Expect = 0.002
Identities = 72/388 (18%), Positives = 154/388 (39%), Gaps = 37/388 (9%)
Query: 2 DHINKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLH 61
+ + Q + E+ R E ER L+ + + A EAL + + ++ QQ+ LAQ E ++
Sbjct: 1594 EEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQK-SLAQAEAEKQK 1652
Query: 62 KMCEDDSRSYASSFSGYSTNTKYDPHQIKAE------IASRR----DRLSRLKRELTQMK 111
+ E ++R + + +++ + A +R L RL+ E Q +
Sbjct: 1653 EEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE 1712
Query: 112 QELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSL 171
Q+ Q E+ + LQ + + K E +A ++++R E L+ S
Sbjct: 1713 QQRQLLEEELARLQR-----EAAAATQKRQELEAELAKVRA----------EMEVLLASK 1757
Query: 172 AKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVD- 230
A+ + +++ + ++ +AG ++ + ++ + E + +
Sbjct: 1758 ARAEEESRSTSEKSKQRLE--------AEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1809
Query: 231 --RVRLNWQYEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLII 288
R R + A K A + + + E EA+ +RL+ + E EA +
Sbjct: 1810 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1869
Query: 289 AQRRSAGDVARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSY 348
A + A RL + R+ + EL R + +R ++E+ L E+A +
Sbjct: 1870 AAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAE 1929
Query: 349 LQSQLKSLCASTLTVSSGSSRGSLASSR 376
L+ +L + ++ + L ++R
Sbjct: 1930 LELELGRIRSNAEDTLRSKEQAELEAAR 1957
Score = 42.0 bits (97), Expect = 0.003
Identities = 67/353 (18%), Positives = 142/353 (40%), Gaps = 77/353 (21%)
Query: 9 QIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDS 68
Q+ E+ RRE E +++ L +EA +K + + +R + EE ++L + E +S
Sbjct: 1960 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQES 2018
Query: 69 RSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKG-VETLQEI 127
Q+ E A +R LQ +EK +Q+
Sbjct: 2019 ARQL---------------QLAQEAAQKR----------------LQAEEKAHAFAVQQK 2047
Query: 128 DRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDS 187
++++ T L + Q+++ +LR +A +E + + + +
Sbjct: 2048 EQELQQT-----LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2102
Query: 188 LVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEEARK---- 243
L ++ A +Q E ++R + E AR+
Sbjct: 2103 LKQSA------------EEQAQARAQAQAAAE-----------KLRKEAEQEAARRAQAE 2139
Query: 244 RVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEE 303
+ A Q+Q A + E AE Q +++K + QEL + Q + + +
Sbjct: 2140 QAALRQKQAADAEMEKHKKFAE------QTLRQKAQVEQELTTLRLQ------LEETDHQ 2187
Query: 304 RERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSL 356
+ L+EEL+R +A + + A +R ++E+ + +Q+EE ++L + ++++ ++L
Sbjct: 2188 KNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRAL 2240
Score = 37.7 bits (86), Expect = 0.060
Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 8/132 (6%)
Query: 942 TLERRTLRYKQSCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQ 1001
T +R QS R+S AE A+ LE LQ QL EE + + E A+
Sbjct: 1555 TAQRSAEAELQSKRASFAEKTAQ----LERSLQEEHVAVAQLREEAERRAQQQAEAERAR 1610
Query: 1002 LRGQTDLPPWVLRDERLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRGQSH 1061
+ +L W L+ L +AE +Q L + AEK ++A +E + RG++
Sbjct: 1611 EEAERELERWQLKANEALRLRLQAEEVAQQKSL---AQAEAEKQKEEAEREA-RRRGKAE 1666
Query: 1062 KEPIQVQTFREK 1073
++ ++ + E+
Sbjct: 1667 EQAVRQRELAEQ 1678
Score = 36.2 bits (82), Expect = 0.17
Identities = 84/369 (22%), Positives = 147/369 (39%), Gaps = 51/369 (13%)
Query: 732 EPSRTREAGCAGESSARDPAHTI--SISGKTDAVTVLLARTTAQLQAVER---ELAEERA 786
E +R R+ E R+ + S++ + +A + A L+ VER ++ E R
Sbjct: 1954 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR----QRKAALEEVERLKAKVEEARR 2009
Query: 787 KLEYTEEEV---LEMERKEEQAEAISERSWQADSVDSGCSNCTQTSPPYPEPCCMGIDSI 843
E E+E L++ ++ Q +E A +V QT +D +
Sbjct: 2010 LRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQL 2065
Query: 844 LGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASL---VKERPSRRARGSPFVR 900
G A+A + E+ + + ++ ++E +EEA L +E+ RA+
Sbjct: 2066 RGE---AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2122
Query: 901 SGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVRNTLERRTLRYKQSCRSSLAE 960
Q + A+++ + +D+ K +TLR K L
Sbjct: 2123 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK------FAEQTLRQKAQVEQELTT 2176
Query: 961 LMARTS--------LDLELD-LQASRT---RQR-QLNEELCALRELRQRLEDAQLRGQTD 1007
L + LD EL L+A T RQR Q+ EEL ++R + L + R + +
Sbjct: 2177 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2236
Query: 1008 LPPWVLRDE--RLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRGQSHKEPI 1065
+LRD+ R L EAE K+ E+AA L A++E +LR + ++
Sbjct: 2237 NRALILRDKDNTQRFLQEEAE------KMKQVAEEAAR--LSVAAQEAARLRQLAEEDLA 2288
Query: 1066 QVQTFREKI 1074
Q + EK+
Sbjct: 2289 QQRALAEKM 2297
Score = 33.1 bits (74), Expect = 1.5
Identities = 68/357 (19%), Positives = 139/357 (38%), Gaps = 30/357 (8%)
Query: 717 EMQLRWHSVQVFTSSEPSRTREAGCAGESSARD----PAHTISISGKTDAVTVLLARTTA 772
E+QL + Q+ + P++ + ES ++ H ++ T ++ T
Sbjct: 1269 ELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLR 1328
Query: 773 QLQAVERELAEERAK-LEYTEEEVLEMERKEEQAEAISERSWQADSVDSGCSNCTQTSPP 831
+++ ER ++RA+ E E +E++ + AEA ++ QA+ Q
Sbjct: 1329 RMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ---- 1384
Query: 832 YPEPCCMGIDSILGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASLVKERPSR 891
+ ++ AA Q L+ ++++ ++ + + ER
Sbjct: 1385 ---------EEVVRREEAAVDAQQQKRSIQEE-LQQLRQSSEAEIQAKARQAEAAERSRL 1434
Query: 892 RARGSPFVRSGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVRNTLERRTLRYK 951
R V + ++ GA + R++ ++ R++ L R+
Sbjct: 1435 RIEEEIRVVRLQLEATERQRGGAEGELQALRARAE-EAEAQKRQAQEEAERLRRQVQDES 1493
Query: 952 QSCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQLR-GQTDLPP 1010
Q R + EL +R + E A+R +QR L AL ELR + E+A+ R Q ++
Sbjct: 1494 QRKRQAEVELASRVKAEAE----AAREKQRALQ----ALEELRLQAEEAERRLRQAEVER 1545
Query: 1011 WVLRDERLRGLLREAERQTRQTKLDYRHEQA-AEKMLKKASKEIYQLRGQSHKEPIQ 1066
L R AE + + + + + A E+ L++ + QLR ++ + Q
Sbjct: 1546 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1602
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 57.4 bits (137), Expect = 7e-08
Identities = 78/346 (22%), Positives = 142/346 (41%), Gaps = 40/346 (11%)
Query: 11 EDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRS 70
E+ Q R E+MLKE + QEA K E ++QQ+ ELAQE+ ++L + E ++
Sbjct: 2325 EEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQK-ELAQEQARRLQEDKEQMAQQ 2383
Query: 71 YASSFSGYSTNTKYDPH---QIKAEIASRRDRLSRLKRELTQMKQELQ-YKEKGVETLQE 126
A G+ + + ++ AE + R++ + R + +++ Q ++++ E ++
Sbjct: 2384 LAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEK 2443
Query: 127 IDRKMSSTHTSYKLDEAQAIMSE-----LRTIKKAICTGEKERRDLMHSLAKLTDSFKNS 181
+ R +T L + I + +++AI E+E+ L L +
Sbjct: 2444 LHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM 2503
Query: 182 CSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLV----DRVRLNWQ 237
+V + + + Q F F+ +K +L D V Q
Sbjct: 2504 QTVQQEQL-------LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQ 2556
Query: 238 YEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDV 297
E ++R QQQ+ + S EA R + + + +ELQ + QRR ++
Sbjct: 2557 LREEQQRQ---QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEEL 2613
Query: 298 ARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEAT 343
L EE +RL E+L+ LL+E+ L EE T
Sbjct: 2614 --LAEENQRLREQLQ--------------LLEEQHRAALAHSEEVT 2643
Score = 52.8 bits (125), Expect = 2e-06
Identities = 79/363 (21%), Positives = 152/363 (41%), Gaps = 55/363 (15%)
Query: 34 EALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEI 93
+AL A+ E + ++++ AQEE ++L + +D+S+ Q + E+
Sbjct: 1503 QALRARAEEAEAQKRQ---AQEEAERLRRQVQDESQR---------------KRQAEVEL 1544
Query: 94 ASRRDRLSRLKRELTQMKQELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTI 153
ASR + RE + Q L+ E E +R++ +++ A+ + L T
Sbjct: 1545 ASRVKAEAEAAREKQRALQALEELRLQAE---EAERRLRQA----EVERARQVQVALETA 1597
Query: 154 KKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQ 213
+++ E E + S A+ T + S HV V ++ + +Q
Sbjct: 1598 QRS---AEAELQSKRASFAEKTAQLERSLQ--------EEHVAV----AQLREEAERRAQ 1642
Query: 214 TDIIGEFVFDDKTRLVDR--------VRLNWQYEEARKRVANIQQQLARLDNESWPSTAE 265
E ++ R ++R +RL Q EE ++ + Q + + E+
Sbjct: 1643 QQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARR 1702
Query: 266 ADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEERERLEEELRRARATSAQGATER 325
+ Q ++++E QEL+ QR+ A A ++R E+EL R RA + QG +R
Sbjct: 1703 RGKAEEQAVRQRELAEQELE---KQRQLAEGTA---QQRLAAEQELIRLRAETEQGEQQR 1756
Query: 326 ILLQEKRNCLLMQLEEATRLTSYLQSQLKSLCASTLTVSSGSSRGSLASSRGSLASSRGS 385
LL+E+ L + AT+ L+++L + A + + +R SR + S+
Sbjct: 1757 QLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAE-EESRSTSEKSKQR 1815
Query: 386 LSS 388
L +
Sbjct: 1816 LEA 1818
Score = 42.4 bits (98), Expect = 0.002
Identities = 72/388 (18%), Positives = 154/388 (39%), Gaps = 37/388 (9%)
Query: 2 DHINKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLH 61
+ + Q + E+ R E ER L+ + + A EAL + + ++ QQ+ LAQ E ++
Sbjct: 1635 EEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQK-SLAQAEAEKQK 1693
Query: 62 KMCEDDSRSYASSFSGYSTNTKYDPHQIKAE------IASRR----DRLSRLKRELTQMK 111
+ E ++R + + +++ + A +R L RL+ E Q +
Sbjct: 1694 EEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGE 1753
Query: 112 QELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSL 171
Q+ Q E+ + LQ + + K E +A ++++R E L+ S
Sbjct: 1754 QQRQLLEEELARLQR-----EAAAATQKRQELEAELAKVRA----------EMEVLLASK 1798
Query: 172 AKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVD- 230
A+ + +++ + ++ +AG ++ + ++ + E + +
Sbjct: 1799 ARAEEESRSTSEKSKQRLE--------AEAGRFRELAEEAARLRALAEEAKRQRQLAEED 1850
Query: 231 --RVRLNWQYEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLII 288
R R + A K A + + + E EA+ +RL+ + E EA +
Sbjct: 1851 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQ 1910
Query: 289 AQRRSAGDVARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSY 348
A + A RL + R+ + EL R + +R ++E+ L E+A +
Sbjct: 1911 AAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAE 1970
Query: 349 LQSQLKSLCASTLTVSSGSSRGSLASSR 376
L+ +L + ++ + L ++R
Sbjct: 1971 LELELGRIRSNAEDTLRSKEQAELEAAR 1998
Score = 42.0 bits (97), Expect = 0.003
Identities = 67/353 (18%), Positives = 142/353 (40%), Gaps = 77/353 (21%)
Query: 9 QIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDS 68
Q+ E+ RRE E +++ L +EA +K + + +R + EE ++L + E +S
Sbjct: 2001 QLAAEEERRRREAEERVQKSLAAEEEAARQRKAALE-EVERLKAKVEEARRLRERAEQES 2059
Query: 69 RSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKG-VETLQEI 127
Q+ E A +R LQ +EK +Q+
Sbjct: 2060 ARQL---------------QLAQEAAQKR----------------LQAEEKAHAFAVQQK 2088
Query: 128 DRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDS 187
++++ T L + Q+++ +LR +A +E + + + +
Sbjct: 2089 EQELQQT-----LQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER 2143
Query: 188 LVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEEARK---- 243
L ++ A +Q E ++R + E AR+
Sbjct: 2144 LKQSA------------EEQAQARAQAQAAAE-----------KLRKEAEQEAARRAQAE 2180
Query: 244 RVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEE 303
+ A Q+Q A + E AE Q +++K + QEL + Q + + +
Sbjct: 2181 QAALRQKQAADAEMEKHKKFAE------QTLRQKAQVEQELTTLRLQ------LEETDHQ 2228
Query: 304 RERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSL 356
+ L+EEL+R +A + + A +R ++E+ + +Q+EE ++L + ++++ ++L
Sbjct: 2229 KNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRAL 2281
Score = 37.7 bits (86), Expect = 0.060
Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 8/132 (6%)
Query: 942 TLERRTLRYKQSCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQ 1001
T +R QS R+S AE A+ LE LQ QL EE + + E A+
Sbjct: 1596 TAQRSAEAELQSKRASFAEKTAQ----LERSLQEEHVAVAQLREEAERRAQQQAEAERAR 1651
Query: 1002 LRGQTDLPPWVLRDERLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRGQSH 1061
+ +L W L+ L +AE +Q L + AEK ++A +E + RG++
Sbjct: 1652 EEAERELERWQLKANEALRLRLQAEEVAQQKSL---AQAEAEKQKEEAEREA-RRRGKAE 1707
Query: 1062 KEPIQVQTFREK 1073
++ ++ + E+
Sbjct: 1708 EQAVRQRELAEQ 1719
Score = 36.2 bits (82), Expect = 0.17
Identities = 84/369 (22%), Positives = 147/369 (39%), Gaps = 51/369 (13%)
Query: 732 EPSRTREAGCAGESSARDPAHTI--SISGKTDAVTVLLARTTAQLQAVER---ELAEERA 786
E +R R+ E R+ + S++ + +A + A L+ VER ++ E R
Sbjct: 1995 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAAR----QRKAALEEVERLKAKVEEARR 2050
Query: 787 KLEYTEEEV---LEMERKEEQAEAISERSWQADSVDSGCSNCTQTSPPYPEPCCMGIDSI 843
E E+E L++ ++ Q +E A +V QT +D +
Sbjct: 2051 LRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSV----LDQL 2106
Query: 844 LGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASL---VKERPSRRARGSPFVR 900
G A+A + E+ + + ++ ++E +EEA L +E+ RA+
Sbjct: 2107 RGE---AEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAE 2163
Query: 901 SGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVRNTLERRTLRYKQSCRSSLAE 960
Q + A+++ + +D+ K +TLR K L
Sbjct: 2164 KLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK------FAEQTLRQKAQVEQELTT 2217
Query: 961 LMARTS--------LDLELD-LQASRT---RQR-QLNEELCALRELRQRLEDAQLRGQTD 1007
L + LD EL L+A T RQR Q+ EEL ++R + L + R + +
Sbjct: 2218 LRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAE 2277
Query: 1008 LPPWVLRDE--RLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKEIYQLRGQSHKEPI 1065
+LRD+ R L EAE K+ E+AA L A++E +LR + ++
Sbjct: 2278 NRALILRDKDNTQRFLQEEAE------KMKQVAEEAAR--LSVAAQEAARLRQLAEEDLA 2329
Query: 1066 QVQTFREKI 1074
Q + EK+
Sbjct: 2330 QQRALAEKM 2338
Score = 33.1 bits (74), Expect = 1.5
Identities = 68/357 (19%), Positives = 139/357 (38%), Gaps = 30/357 (8%)
Query: 717 EMQLRWHSVQVFTSSEPSRTREAGCAGESSARD----PAHTISISGKTDAVTVLLARTTA 772
E+QL + Q+ + P++ + ES ++ H ++ T ++ T
Sbjct: 1310 ELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLR 1369
Query: 773 QLQAVERELAEERAK-LEYTEEEVLEMERKEEQAEAISERSWQADSVDSGCSNCTQTSPP 831
+++ ER ++RA+ E E +E++ + AEA ++ QA+ Q
Sbjct: 1370 RMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQ---- 1425
Query: 832 YPEPCCMGIDSILGHPFAAQAGPYSPEKFQPSPLKVDKETNTEDLFLEEAASLVKERPSR 891
+ ++ AA Q L+ ++++ ++ + + ER
Sbjct: 1426 ---------EEVVRREEAAVDAQQQKRSIQEE-LQQLRQSSEAEIQAKARQAEAAERSRL 1475
Query: 892 RARGSPFVRSGTIVRSQTFSPGARSQYVCRLYRSDSDSSTLPRKSPFVRNTLERRTLRYK 951
R V + ++ GA + R++ ++ R++ L R+
Sbjct: 1476 RIEEEIRVVRLQLEATERQRGGAEGELQALRARAE-EAEAQKRQAQEEAERLRRQVQDES 1534
Query: 952 QSCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQLR-GQTDLPP 1010
Q R + EL +R + E A+R +QR L AL ELR + E+A+ R Q ++
Sbjct: 1535 QRKRQAEVELASRVKAEAE----AAREKQRALQ----ALEELRLQAEEAERRLRQAEVER 1586
Query: 1011 WVLRDERLRGLLREAERQTRQTKLDYRHEQA-AEKMLKKASKEIYQLRGQSHKEPIQ 1066
L R AE + + + + + A E+ L++ + QLR ++ + Q
Sbjct: 1587 ARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQ 1643
>gi|56550043 sarcolemma associated protein [Homo sapiens]
Length = 811
Score = 55.8 bits (133), Expect = 2e-07
Identities = 86/407 (21%), Positives = 164/407 (40%), Gaps = 51/407 (12%)
Query: 14 REQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQ---RFELAQEEYQQLHKMCEDDSR- 69
REQ ++ L+ L + QEA + + + + R E+ + Q K +DS
Sbjct: 178 REQMLEQKLATLQRLLAITQEASDTSWQALIDEDRLLSRLEVMGNQLQACSKNQTEDSLR 237
Query: 70 ----SYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKGVETLQ 125
+ Y T K ++ E +LS ++R L+ + E + ++ E Q
Sbjct: 238 KELIALQEDKHNYETTAKESLRRVLQEKIEVVRKLSEVERSLSNTEDECTHLKEMNERTQ 297
Query: 126 EIDRKMSSTHT---------SYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSL----- 171
E R++++ + S KL A+ E++ G+ E+++L H +
Sbjct: 298 EELRELANKYNGAVNEIKDLSDKLKVAEGKQEEIQQ------KGQAEKKELQHKIDEMEE 351
Query: 172 ------AKLTDSFKNSCSVTDSLVDFPHHV--GVPGDAGVPQQFCDAGSQTDIIGEFVFD 223
AK+ ++ + L H+ GD QF + + + G
Sbjct: 352 KEQELQAKIEALQADNDFTNERLTALQEHLLSKSGGDCTFIHQFIECQKKLIVEGHL--- 408
Query: 224 DKTRLVDRVRLNWQYEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQE 283
T+ V+ +L+ + + R + ++ L+ +S T +A D L + L +
Sbjct: 409 --TKAVEETKLSKE-NQTRAKESDFSDTLSPSKEKSSDDTTDAQMDEQDLNEP----LAK 461
Query: 284 LQLIIAQRRSAGDVARLEEERERLEEELRRARA---TSAQGATE-RILLQEKRNCLLMQL 339
+ L+ + A ++E + L +EL A+ TS Q E + LL+E+R Q+
Sbjct: 462 VSLLKDDLQGAQSEIEAKQEIQHLRKELIEAQELARTSKQKCFELQALLEEERKAYRNQV 521
Query: 340 EEATRLTSYLQSQLKSLCASTLTVSSGSSRGSLASSRGSLASSRGSL 386
EE+T+ LQ+QL+ L T + + S+R L S+R +
Sbjct: 522 EESTKQIQVLQAQLQRLHIDTENLRE-EKDSEITSTRDELLSARDEI 567
Score = 48.5 bits (114), Expect = 3e-05
Identities = 40/129 (31%), Positives = 60/129 (46%), Gaps = 12/129 (9%)
Query: 237 QYEEARKRVANIQQQLARLD------NESWPSTAEADRDRLQLIKEKEALLQELQLIIAQ 290
Q EE+ K++ +Q QL RL E S + RD L +++ LL + +A
Sbjct: 520 QVEESTKQIQVLQAQLQRLHIDTENLREEKDSEITSTRDELLSARDEILLLHQAAAKVAS 579
Query: 291 RRSAGDVARLEEERERLEEELRRARATSAQGATERILLQEK-----RNCLLMQLEEATRL 345
R D+A L+EE +++ EL R R +++ E LQ + C Q EEATRL
Sbjct: 580 ERDT-DIASLQEELKKVRAELERWRKAASEYEKEITSLQNSFQLRCQQCEDQQREEATRL 638
Query: 346 TSYLQSQLK 354
L+ K
Sbjct: 639 QGELEKLRK 647
Score = 30.8 bits (68), Expect = 7.3
Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 7/80 (8%)
Query: 54 QEEYQQLHKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQE 113
Q +Q + CED R A+ G + + + ++ E S LKRE + E
Sbjct: 617 QNSFQLRCQQCEDQQREEATRLQGELEKLRKEWNALETECHS-------LKRENVLLSSE 669
Query: 114 LQYKEKGVETLQEIDRKMSS 133
LQ +EK + Q+ +++S
Sbjct: 670 LQRQEKELHNSQKQSLELTS 689
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 52.8 bits (125), Expect = 2e-06
Identities = 62/338 (18%), Positives = 151/338 (44%), Gaps = 24/338 (7%)
Query: 40 KEIYQIKQQRFELAQEEYQQLHKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDR 99
K++ ++K+++ + Q++ + L + D + ++ + + D +A+ +
Sbjct: 531 KDMLEVKERKINVLQKKIENLQEQLRDKDKQL-TNLKDRVKSLQTDSSNTDTALATLEEA 589
Query: 100 LSRLKRELTQMKQELQYKEKGVETLQEI--------DRKMSSTHTSYKLDEAQAIMSELR 151
LS +R + ++K++ + ++ E L+EI D K +L E ++ + +L+
Sbjct: 590 LSEKERIIERLKEQRERDDR--ERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLK 647
Query: 152 TIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAG 211
++ + +R + SL + K CS ++ + H+ + D+ + +F D
Sbjct: 648 EHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHN--IEDDSRMNPEFADQI 705
Query: 212 SQTDIIGEFVFDDKTRL---VDRV-----RLNWQYEEARKRVANIQQQLARLDNESWPST 263
Q D + D+ + VDR+ + + + K++A ++ R +
Sbjct: 706 KQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKV 765
Query: 264 AEADRDRLQLIKEKEA-LLQELQLIIAQRRSAGDVARLEEERERLEEELRRARATSAQ-G 321
A ++ QL K+K A LL+E++ ++EE LE+ + AT A+
Sbjct: 766 ANLKHNQ-QLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLA 824
Query: 322 ATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSLCAS 359
+T++ L +++ + +++E +L L+ + ++L A+
Sbjct: 825 STQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAA 862
Score = 38.5 bits (88), Expect = 0.035
Identities = 68/285 (23%), Positives = 122/285 (42%), Gaps = 37/285 (12%)
Query: 81 NTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKGVETLQEIDRKMSSTHTSYKL 140
NT+ +IK +I + +K ++ Q+KQEL KE + LQ +S+ ++ K
Sbjct: 411 NTEDREEEIK-QIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDCK- 468
Query: 141 DEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGD 200
+ ++ E T K+ + D + + +SF N T L D G
Sbjct: 469 -QHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLN--KKTKQLQDLTEEKGTL-- 523
Query: 201 AGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVR-----LNWQYEEARKRVANIQQQLARL 255
AG D+ + + + K R ++ ++ L Q + K++ N++ ++ L
Sbjct: 524 ---------AGEIRDM--KDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSL 572
Query: 256 DNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEE-ERERLEEELRRA 314
+S +T A + + EKE +++ L+ ++R D RLEE E R E + +
Sbjct: 573 QTDS-SNTDTALATLEEALSEKERIIERLK----EQRERDDRERLEEIESFRKENKDLKE 627
Query: 315 RATSAQGATERILLQEKRNCLLMQLEEATRLTS---YLQSQLKSL 356
+ + Q L EK + L+ E A+ L S S+LKSL
Sbjct: 628 KVNALQAE-----LTEKESSLIDLKEHASSLASAGLKRDSKLKSL 667
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 52.0 bits (123), Expect = 3e-06
Identities = 77/364 (21%), Positives = 155/364 (42%), Gaps = 48/364 (13%)
Query: 8 TQIEDPREQWRREQERMLKEYLIVA--QEALNAKKEIYQIKQQRFELAQEEYQ-QLHKMC 64
T+++ + R+E+E M KE +V ++ L A+ + +++ + +L E+ Q Q
Sbjct: 832 TKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQA 891
Query: 65 EDDSRSYASSFSGYSTNTKYDP----HQIKAEIASRRDRLSRLKRELTQMKQELQYKEKG 120
E + + A T K + H ++A + +R L+ E +M+Q +Q E+
Sbjct: 892 ETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQ 951
Query: 121 VETLQEIDRKMSSTHTSY-----KLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLT 175
+E + +K+ + KL+E Q I+ + C KE++ L +A+ T
Sbjct: 952 LEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQN------CKLAKEKKLLEDRIAEFT 1005
Query: 176 DSFKNSCSVTDSLVDFPH-HVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLV---DR 231
+ + SL + H + D + ++ Q + +KTR D
Sbjct: 1006 TNLTEEEEKSKSLAKLKNKHEAMITD--LEERLRREEKQRQEL------EKTRRKLEGDS 1057
Query: 232 VRLNWQYEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQR 291
L+ Q E + ++A ++ QLA+ + E + A + + Q K L++++
Sbjct: 1058 TDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQ----KNMALKKIR------ 1107
Query: 292 RSAGDVARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQS 351
LE + L+E+L RA+ + ++ L E+ L +LE+ T+ Q
Sbjct: 1108 -------ELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA-AQQ 1159
Query: 352 QLKS 355
+L+S
Sbjct: 1160 ELRS 1163
Score = 35.0 bits (79), Expect = 0.39
Identities = 61/307 (19%), Positives = 125/307 (40%), Gaps = 36/307 (11%)
Query: 47 QQRFELAQEEYQQLH------KMCEDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRL 100
Q EL QEE +Q K ED+ S+ + H ++ +IA+
Sbjct: 1311 QDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLE----EEEEAKHNLEKQIAT----- 1361
Query: 101 SRLKRELTQMKQELQYKEKGVETLQEIDRKMSS--THTSYKLDEAQAIMSELRTIKKAIC 158
L ++ MK++++ +ET +E+ RK+ S + +E A +L K +
Sbjct: 1362 --LHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRL- 1418
Query: 159 TGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIG 218
++E DL L L +++C++ F + + + ++ + + +
Sbjct: 1419 --QQELDDL---LVDLDHQRQSACNLEKKQKKFDQLLA--EEKTISAKYAEERDRAEAEA 1471
Query: 219 EFVFDDKTRLVDRVRLNWQYEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKE 278
+ +T+ + R + E + + + +Q + S + + +L K K
Sbjct: 1472 R---EKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKR 1528
Query: 279 ALLQELQLIIAQRRSAGD-VARLEEERERLEEELRRARA---TSAQGATERILLQEKRNC 334
AL Q+++ + Q D + E+ + RLE L+ +A QG E+ +EK+
Sbjct: 1529 ALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQ--SEEKKKQ 1586
Query: 335 LLMQLEE 341
L+ Q+ E
Sbjct: 1587 LVRQVRE 1593
Score = 31.6 bits (70), Expect = 4.3
Identities = 67/363 (18%), Positives = 144/363 (39%), Gaps = 36/363 (9%)
Query: 9 QIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFE-LAQEEYQQLHKMCEDD 67
++E + + ++E + +L + Q A N +K KQ++F+ L EE K E+
Sbjct: 1410 KLEKTKTRLQQELDDLLVDLDHQRQSACNLEK-----KQKKFDQLLAEEKTISAKYAEER 1464
Query: 68 SRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKREL-TQMKQELQYKEKGVETLQE 126
R+ A + + E ++ L RL ++ T+M+ + K+ +++ E
Sbjct: 1465 DRAEAEARE--KETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHE 1522
Query: 127 IDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTD 186
+++ + + + + ++L ++ + E + L +L + F+ D
Sbjct: 1523 LEKSKRALE-----QQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRD 1577
Query: 187 SLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIG------EFVFDDKTRLVDRVRLNWQYEE 240
+ V + + D Q + E D +D N +E
Sbjct: 1578 EQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKN--RDE 1635
Query: 241 ARKRVANIQQQL---------ARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQR 291
A K++ +Q Q+ R E + A+ + +L+ ++ + LQE +L A+R
Sbjct: 1636 AIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQE-ELAAAER 1694
Query: 292 RSAGDVARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQS 351
+ ++ER+ L +E+ + A E+ L+ + L +LEE T +
Sbjct: 1695 AKR----QAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELIND 1750
Query: 352 QLK 354
+LK
Sbjct: 1751 RLK 1753
>gi|169208042 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 2 [Homo sapiens]
Length = 595
Score = 49.3 bits (116), Expect = 2e-05
Identities = 70/329 (21%), Positives = 136/329 (41%), Gaps = 30/329 (9%)
Query: 87 HQIKAEIASRRDRLSRLKRELTQMKQELQYKEKGVET-LQEIDRKM-----SSTHTSYKL 140
HQ++ E + +R + +REL Q L +++ + T L ++R + S + +L
Sbjct: 104 HQLEEEKKANNER-QKAERELEVQIQTLIIQKEELNTDLYHMERSLRYFEEESKDLAVRL 162
Query: 141 DEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGD 200
+ EL + A+ EK++ + + S +K ++ S+ D + +
Sbjct: 163 QHSLQCKGELESALSAVIATEKKKANQLSSCSKAHTEWELEQSLQDQALLKAQLTQLK-- 220
Query: 201 AGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVR--------LNWQYEEARKRVANIQQQL 252
+ F + D E + ++ R R+ L + ++ +RV +++ L
Sbjct: 221 ----ESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKEKQQDMRRVEELERSL 276
Query: 253 ARLDNESW------PSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEERER 306
++L N+ P ++ + L KE E + ELQ + + + R +EER R
Sbjct: 277 SKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQHISLLNRRQEERIR 336
Query: 307 LEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSLCASTLTV--S 364
+EE R + Q E++ K + +L + T L+ Q+K L V +
Sbjct: 337 EQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEVKET 396
Query: 365 SGSSRGSLASSRGSLASSRGSLSSVSFTD 393
S++ ++RG A G SS SF D
Sbjct: 397 ETSAQKEPEAARGPGAPGPGGESS-SFMD 424
>gi|169208038 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 2 [Homo sapiens]
Length = 595
Score = 49.3 bits (116), Expect = 2e-05
Identities = 70/329 (21%), Positives = 136/329 (41%), Gaps = 30/329 (9%)
Query: 87 HQIKAEIASRRDRLSRLKRELTQMKQELQYKEKGVET-LQEIDRKM-----SSTHTSYKL 140
HQ++ E + +R + +REL Q L +++ + T L ++R + S + +L
Sbjct: 104 HQLEEEKKANNER-QKAERELEVQIQTLIIQKEELNTDLYHMERSLRYFEEESKDLAVRL 162
Query: 141 DEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGD 200
+ EL + A+ EK++ + + S +K ++ S+ D + +
Sbjct: 163 QHSLQCKGELESALSAVIATEKKKANQLSSCSKAHTEWELEQSLQDQALLKAQLTQLK-- 220
Query: 201 AGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVR--------LNWQYEEARKRVANIQQQL 252
+ F + D E + ++ R R+ L + ++ +RV +++ L
Sbjct: 221 ----ESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKEKQQDMRRVEELERSL 276
Query: 253 ARLDNESW------PSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEERER 306
++L N+ P ++ + L KE E + ELQ + + + R +EER R
Sbjct: 277 SKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQHISLLNRRQEERIR 336
Query: 307 LEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSLCASTLTV--S 364
+EE R + Q E++ K + +L + T L+ Q+K L V +
Sbjct: 337 EQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEVKET 396
Query: 365 SGSSRGSLASSRGSLASSRGSLSSVSFTD 393
S++ ++RG A G SS SF D
Sbjct: 397 ETSAQKEPEAARGPGAPGPGGESS-SFMD 424
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 49.3 bits (116), Expect = 2e-05
Identities = 69/368 (18%), Positives = 157/368 (42%), Gaps = 52/368 (14%)
Query: 2 DHINKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLH 61
+ + +L +E R ++R L++ L V + + +E+ ++Q +L Q+ QQL
Sbjct: 639 EELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGREL---EEQNLQL-QKTLQQLR 694
Query: 62 KMCEDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKGV 121
+ CE+ S++ + +T ++ + ++ +R + ++Q+L+ V
Sbjct: 695 QDCEEASKAKMVA-EAEATVLGQRRAAVETTLRETQEENDEFRRRILGLEQQLKETRGLV 753
Query: 122 ETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNS 181
+ + ++ ++ D+ Q + +E + +++A+ ++E L + L + +
Sbjct: 754 DGGEAVEARLR--------DKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEA 805
Query: 182 CSVTDSLVDFPHHVGVPGDAGVPQQFC-----DAGSQTDII--GEFVFDDKTRLVDRV-- 232
L G QQ + G Q +++ G+ +++ RL+DR
Sbjct: 806 QRGLARL-------------GQEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVD 852
Query: 233 RLNWQYE----EARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLII 288
RLN + E ++++ + +Q QL ++ A+A R E E
Sbjct: 853 RLNKELEKIGEDSKQALQQLQAQLEDYKEKARREVADAQRQAKDWASEAE---------- 902
Query: 289 AQRRSAGDVARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSY 348
+++G ++RL++E +RL + L+ ++A ++ LL ++ L + E R
Sbjct: 903 ---KTSGGLSRLQDEIQRLRQALQASQAERDTARLDKELLAQRLQGLEQEAENKKRSQDD 959
Query: 349 LQSQLKSL 356
QLK L
Sbjct: 960 RARQLKGL 967
Score = 33.5 bits (75), Expect = 1.1
Identities = 71/395 (17%), Positives = 159/395 (40%), Gaps = 53/395 (13%)
Query: 14 REQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRSYAS 73
RE RR + + ++ ++ + KE+ +I + + Q+ QL E R A
Sbjct: 830 REVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDSKQALQQLQAQLEDYKEKARREVAD 889
Query: 74 SFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKGVETLQEIDRKMSS 133
+ + +E LSRL+ E+ +++Q LQ + +T + +D+++ +
Sbjct: 890 A--------QRQAKDWASEAEKTSGGLSRLQDEIQRLRQALQASQAERDTAR-LDKELLA 940
Query: 134 THTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPH 193
Q + E K++ ++ + L +++L + + L D +
Sbjct: 941 -------QRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETELDEEKNTVELLTDRVN 993
Query: 194 HVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEEARKRVANIQ---- 249
D + + ++ D+ D++ L Q ++ + R+A+ +
Sbjct: 994 RGRDQVDQLRTELMQERSARQDLE-----------CDKISLERQNKDLKTRLASSEGFQK 1042
Query: 250 --QQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEERERL 307
L++L++++ + ++RLQ + ++ +LQ + ++ + ++E+ER+ +
Sbjct: 1043 PSASLSQLESQN-----QLLQERLQAEEREKTVLQSTNRKLERKVKELSI-QIEDERQHV 1096
Query: 308 EEE-----LR-RARATSAQGATERI-LLQEKRNCLLMQLEEATRLTSYLQSQLKSLCAST 360
++ LR +A A E I L R ++EE + LQ+++KSL
Sbjct: 1097 NDQKDQLSLRVKALKRQVDEAEEEIERLDGLRKKAQREVEEQHEVNEQLQARIKSL---- 1152
Query: 361 LTVSSGSSRGSLASSRGSLASSRGSLSSVSFTDIY 395
S R + S+ S + G S F +Y
Sbjct: 1153 ---EKDSWRKASRSAAESALKNEGLSSDEEFDSVY 1184
Score = 30.8 bits (68), Expect = 7.3
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 4/104 (3%)
Query: 950 YKQSCRSSLAELMARTSLDLELDLQASRTRQRQLNEELCALRELRQRLEDAQLRGQTDLP 1009
YK+ R +A+ R + D + + + +L +E+ + LRQ L+ +Q T
Sbjct: 879 YKEKARREVADAQ-RQAKDWASEAEKTSGGLSRLQDEI---QRLRQALQASQAERDTARL 934
Query: 1010 PWVLRDERLRGLLREAERQTRQTKLDYRHEQAAEKMLKKASKEI 1053
L +RL+GL +EAE + R R + E+ + + E+
Sbjct: 935 DKELLAQRLQGLEQEAENKKRSQDDRARQLKGLEEKVSRLETEL 978
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 48.9 bits (115), Expect = 3e-05
Identities = 75/363 (20%), Positives = 157/363 (43%), Gaps = 49/363 (13%)
Query: 29 LIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRSYASSFSGYSTNTKYDPHQ 88
L + ++ + K E+ Q + +L E L + + ++ S + ++
Sbjct: 801 LSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRH---- 856
Query: 89 IKAEIASRRDRLSRLKRELTQMKQELQYKEKGVETLQEI--DRKMSSTHTSYKLDEAQAI 146
I +++ LS+ + E+T+M Q L K++ VETLQ+ ++ T S+ + E
Sbjct: 857 ISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEK--- 913
Query: 147 MSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQ 206
M +L K ++ K ++ ++ L++ ++ K + + +G+ Q
Sbjct: 914 MVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEV-----------SSGLKQN 962
Query: 207 FCDAG-----SQTDIIGEFVF-----DDKTRLVDRVRLNWQYEEARKRVANIQQQLARLD 256
+ + S+ ++ EF + + R + +N +E +RV+ ++++LA L
Sbjct: 963 YDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALIN--RKELLQRVSRLEEELANLK 1020
Query: 257 NESWPSTAEADRDRLQLIKEKE----------ALLQELQLIIAQRRSAGDVARLEEERER 306
+ES ++ +R ++ ++KE + QE+++ + Q S +V L+ R+
Sbjct: 1021 DESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEV-ELQHIRKD 1079
Query: 307 LEEELRRARATSAQGATERILLQEKRNCL-LMQLEEATRLTSYLQSQLKSLCASTLTVSS 365
LEE+L A LQ+K N + L+Q E S Q+ ++ L S S
Sbjct: 1080 LEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAE-----ISENQAIIQKLITSNTDASD 1134
Query: 366 GSS 368
G S
Sbjct: 1135 GDS 1137
Score = 48.5 bits (114), Expect = 3e-05
Identities = 75/374 (20%), Positives = 156/374 (41%), Gaps = 74/374 (19%)
Query: 6 KLTQIEDPREQWRREQERMLKEYLIVAQEALNA-KKEIYQIKQQRFELAQEEYQQLHKMC 64
+L Q ++ ++ R+ + +K+ + A+ L + K I ++K Q + E Q ++
Sbjct: 74 QLQQKDEALQEERKAADNKIKKLKLHAKAKLTSLNKYIEEMKAQGGTVLPTEPQSEEQLS 133
Query: 65 EDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQ--------------- 109
+ D S T + + +IK ++ + + +S L+ +LTQ
Sbjct: 134 KHDKSS---------TEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEE 184
Query: 110 ---MKQELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRD 166
MKQ+LQ KE+ + TLQ +L + QA + + +++ E + R
Sbjct: 185 FVMMKQQLQEKEEFISTLQA------------QLSQTQAEQAAQQVVREKDARFETQVRL 232
Query: 167 LMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKT 226
L +L + L V Q+ + ++ ++G +
Sbjct: 233 HEDELLQLVTQADVETEMQQKL-------------RVLQRKLEEHEES-LVG------RA 272
Query: 227 RLVDRVRLNWQYEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQL 286
++VD ++ E R ++ + Q Q ++ + +T E +R+ E + LL++++L
Sbjct: 273 QVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETERE------ESKILLEKMEL 326
Query: 287 IIAQRRSAGDVARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLT 346
+A+R+ + L+EE L E+ +A A+ + L++K ++EE T
Sbjct: 327 EVAERKLS--FHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKA---EMEEKTSHI 381
Query: 347 SYLQ---SQLKSLC 357
LQ +L+S C
Sbjct: 382 LSLQKTGQELQSAC 395
Score = 40.0 bits (92), Expect = 0.012
Identities = 59/278 (21%), Positives = 119/278 (42%), Gaps = 27/278 (9%)
Query: 89 IKAEIASRRDRLSRLKRELTQMKQELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMS 148
++ E ++ L+ E + ++ K+ ++ LQE KM+ + Q I
Sbjct: 1852 LEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLN--------QQIQE 1903
Query: 149 ELRTIKKAICTGEKERRDL----MHSLAKLTDSFKNSCS-VTDSLVDFPHHVGVPGDAGV 203
EL + K T E+E+ DL M+ LA+L S N C VTD+ +
Sbjct: 1904 ELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELL------ESE 1957
Query: 204 PQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNW--QYEEARKRVANIQ--QQLARLDNES 259
+ S+ + + + +KT++ +R + + + A+K N ++L L E
Sbjct: 1958 MKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEK 2017
Query: 260 WPSTAEADRDRLQLIKEKEALLQELQLI-IAQRRSAGDVARLEEERERLEEELRRARATS 318
+ +D ++ ++ AL + ++ + Q S D LE +E L + + +
Sbjct: 2018 QQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKD---LEITKENLAQAVEHRKKAQ 2074
Query: 319 AQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSL 356
A+ A+ ++LL + ++ L + +L LQS +S+
Sbjct: 2075 AELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESV 2112
Score = 40.0 bits (92), Expect = 0.012
Identities = 69/366 (18%), Positives = 147/366 (40%), Gaps = 50/366 (13%)
Query: 7 LTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQ--EEYQQLHKMC 64
L+Q+E+ R + Q + K + E+ +K Q +L+ E+ ++
Sbjct: 2290 LSQLEETRHLYHSSQNELAK-----------LESELKSLKDQLTDLSNSLEKCKEQKGNL 2338
Query: 65 EDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQE----LQYKEKG 120
E R + N+K+ Q++ ++ + R+ SRL E+ +Q+ L KE+
Sbjct: 2339 EGIIRQQEADIQ----NSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEA 2394
Query: 121 V-----ETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLT 175
+ E Q+ D+++ +E + I+ E KKA+ + LM +L +
Sbjct: 2395 IQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEEN-KKAV----DKTNQLMETLKTIK 2449
Query: 176 DSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLN 235
+ DS V + + I+G++ ++ L + +
Sbjct: 2450 KENIQQKAQLDSFVKSMSSL--------------QNDRDRIVGDYQQLEERHLSIILEKD 2495
Query: 236 WQYEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAG 295
+EA +++++ L + +E + +LI+ +E L Q + + +Q++
Sbjct: 2496 QLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLL 2555
Query: 296 DV-----ARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQ 350
+V LE + +LEE+L+ + + LQE++ L ++E S L
Sbjct: 2556 EVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLT 2615
Query: 351 SQLKSL 356
Q+ +L
Sbjct: 2616 RQVTAL 2621
Score = 38.1 bits (87), Expect = 0.046
Identities = 69/348 (19%), Positives = 138/348 (39%), Gaps = 54/348 (15%)
Query: 23 RMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRSYASSFSGYSTNT 82
+ LKE L + A AKKE + + ++ Y ++ + F
Sbjct: 929 KTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKEN 988
Query: 83 KYDPHQIKAEIASRRDRL---SRLKRELTQMKQE------LQYKEKGVETLQEIDRKMSS 133
+ +++A + +R++ L SRL+ EL +K E L E+G + +++ S
Sbjct: 989 EQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSE 1048
Query: 134 THTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPH 193
+ K E + + + TI + + R+DL LA + F+ +LV
Sbjct: 1049 KCVTSKCQEIEIYLKQ--TISEKEVELQHIRKDLEEKLA-AEEQFQ-------ALV---- 1094
Query: 194 HVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEEARKRVANIQQQL- 252
+ Q D +Q D++ + +++ + + N + VA +++ +
Sbjct: 1095 -------KQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDG-DSVALVKETVV 1146
Query: 253 ----ARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEERERLE 308
+E W E + L L KEKE L ++LQ + R++ + + +E+ L
Sbjct: 1147 ISPPCTGSSEHW--KPELEEKILALEKEKEQLQKKLQEALTSRKAI--LKKAQEKERHLR 1202
Query: 309 EELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSL 356
EEL++ + + N L Q +E ++ + QL+ L
Sbjct: 1203 EELKQQK--------------DDYNRLQEQFDEQSKENENIGDQLRQL 1236
Score = 37.7 bits (86), Expect = 0.060
Identities = 63/339 (18%), Positives = 128/339 (37%), Gaps = 46/339 (13%)
Query: 29 LIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRSYASSFSGYSTNTKYDPHQ 88
L V +E ++ ++ Q+R +EE + K + +D
Sbjct: 2634 LKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGI 2693
Query: 89 IKAEIASRRDRLSRLKRELTQMKQEL---QYKEKGVET-LQEIDRKMSS-----THTSYK 139
++ E + +R++ L R+L +M+Q+L + KG+ +Q R MSS H + +
Sbjct: 2694 MRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEE 2753
Query: 140 LDEAQ----AIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHV 195
LDE + A + EL +K+ + L + + + +NS S + L
Sbjct: 2754 LDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKL------- 2806
Query: 196 GVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEEARKRVANIQQQLARL 255
QQ Q + L+ Q E++ +V + + +A L
Sbjct: 2807 --------NQQLLSKDEQL-----------------LHLSSQLEDSYNQVQSFSKAMASL 2841
Query: 256 DNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEERERLEEELRRAR 315
NE E ++ R ++ + Q + ++ L+ +R+RL +EL+ +
Sbjct: 2842 QNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQ 2901
Query: 316 ATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLK 354
Q + I L + ++ T+ +Q +L+
Sbjct: 2902 QQYLQ-INQEITELHPLKAQLQEYQDKTKAFQIMQEELR 2939
Score = 36.2 bits (82), Expect = 0.17
Identities = 64/318 (20%), Positives = 123/318 (38%), Gaps = 64/318 (20%)
Query: 88 QIKAEIASRRDRLSRLKRELTQMKQELQYKEKGVETLQEIDRKMSSTHTSYK--LDEAQA 145
Q++ + +R+ +L+ EL +MKQ+ + + Q+I RK+ + S K L E ++
Sbjct: 1442 QLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKS 1501
Query: 146 IMSE--------------LRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTD-SLVD 190
+ E L ++ + KE+ ++ LA L + + D SL++
Sbjct: 1502 LQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLE 1561
Query: 191 FPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVR----------LNWQ--Y 238
Q + + E + +DK +LV + WQ +
Sbjct: 1562 -------------NQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKH 1608
Query: 239 EEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSA---- 294
+E +K + Q + NE+ +R+Q + EA+ QE Q + + RS
Sbjct: 1609 KELQKEYEILLQSYENVSNEA---------ERIQHV--VEAVRQEKQELYGKLRSTEANK 1657
Query: 295 GDVARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLK 354
+ + +E E+ EE++ A+ ++IL E+ N + R +
Sbjct: 1658 KETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEEN-------DRLRAEVHPAGDTA 1710
Query: 355 SLCASTLTVSSGSSRGSL 372
C TL S+ S + L
Sbjct: 1711 KECMETLLSSNASMKEEL 1728
Score = 33.9 bits (76), Expect = 0.86
Identities = 69/383 (18%), Positives = 148/383 (38%), Gaps = 56/383 (14%)
Query: 4 INKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQE-------- 55
+ +L +++ R++ E +R L E ++ + K + + + + +L +E
Sbjct: 1538 LGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSK 1597
Query: 56 -----EYQQLHKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQM 110
E+Q+ HK + + S+ S + H ++A +++ +L+
Sbjct: 1598 IAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANK 1657
Query: 111 KQ---ELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRT-IKKAICTGEKERRD 166
K+ +LQ E+ +E ++E RK + + K+ E + LR + A T ++
Sbjct: 1658 KETEKQLQEAEQEMEEMKEKMRKFAKS-KQQKILELEEENDRLRAEVHPAGDTAKECMET 1716
Query: 167 LMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKT 226
L+ S A + + + ++L ++F S+ D + E V D K
Sbjct: 1717 LLSSNASMKEELERVKMEYETL---------------SKKFQSLMSEKDSLSEEVQDLKH 1761
Query: 227 RLVDRVRLNWQYEEARKRVANIQQQLARLDNESWPSTAEADRDRLQL-----IKEKEALL 281
++ V E K + Q + +S P E ++D L + E
Sbjct: 1762 QIEGNVSKQANLEATEKH--DNQTNVTEEGTQSIPGETE-EQDSLSMSTRPTCSESVPSA 1818
Query: 282 QELQLIIAQRRSAGD--------VARLEEERERLEEELRRARATSAQGATERILLQEKRN 333
+ +++ S+ D + +L+E LEEE ++ + S L+ ++N
Sbjct: 1819 KSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQ-------TLENEKN 1871
Query: 334 CLLMQLEEATRLTSYLQSQLKSL 356
LL Q+ LQ ++ +
Sbjct: 1872 TLLSQISTKDGELKMLQEEVTKM 1894
Score = 32.0 bits (71), Expect = 3.3
Identities = 75/365 (20%), Positives = 138/365 (37%), Gaps = 61/365 (16%)
Query: 7 LTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCED 66
L+QI + + QE + K L+ Q ++E+ ++ + + E A+EE L + +
Sbjct: 1874 LSQISTKDGELKMLQEEVTKMNLLNQQ----IQEELSRVTKLK-ETAEEEKDDLEERLMN 1928
Query: 67 DSRSYASSFSGYSTNTKYDPHQIKAEIA-SRRDRLSRLKRELTQMKQELQYKEKGVET-- 123
S Y + QIK E+ S L + EL + KQ+L ++ VE+
Sbjct: 1929 QLAELNGSIGNYCQDVT--DAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEI 1986
Query: 124 ----LQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAI---CTGEKERRDLMHSLAKL-- 174
L++I E Q ++ E + K + C +E+ + K
Sbjct: 1987 RKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALE 2046
Query: 175 ---TDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTR---- 227
T+S K+ ++L H +Q ++ V D T+
Sbjct: 2047 FVQTESQKDLEITKENLAQAVEH--------------RKKAQAELASFKVLLDDTQSEAA 2092
Query: 228 --LVDRVRLNWQYEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQ 285
L D ++L +E + +++ Q+ + D + +A+ L KEK+ + ++L
Sbjct: 2093 RVLADNLKLK---KELQSNKESVKSQMKQKDEDLERRLEQAEEKHL---KEKKNMQEKLD 2146
Query: 286 LIIAQRRSAGDVARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRL 345
L E+ LEE + + T + E LQE + + QL T+
Sbjct: 2147 A-------------LRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKS 2193
Query: 346 TSYLQ 350
S LQ
Sbjct: 2194 MSSLQ 2198
>gi|169208018 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 3 [Homo sapiens]
Length = 595
Score = 48.5 bits (114), Expect = 3e-05
Identities = 70/329 (21%), Positives = 135/329 (41%), Gaps = 30/329 (9%)
Query: 87 HQIKAEIASRRDRLSRLKRELTQMKQELQYKEKGVET-LQEIDRKM-----SSTHTSYKL 140
HQ++ E + +R + +REL Q L +++ + T L ++R + S + +L
Sbjct: 104 HQLEEEKKANNER-QKAERELEVQIQTLIIQKEELNTDLYHMERSLRYFEEESKDLAVRL 162
Query: 141 DEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGD 200
+ EL A+ EK++ + + S +K ++ S+ D + +
Sbjct: 163 QHSLQCKGELERALSAVIATEKKKANQLSSCSKAHTEWELEQSLQDQALLKAQLTQLK-- 220
Query: 201 AGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVR--------LNWQYEEARKRVANIQQQL 252
+ F + D E + ++ R R+ L + ++ +RV +++ L
Sbjct: 221 ----ESFQQLQLERDECAEHIEGERARWHQRMSKMLQEICTLKKEKQQDMRRVEELERSL 276
Query: 253 ARLDNESW------PSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEERER 306
++L N+ P ++ + L KE E + ELQ + + + R +EER R
Sbjct: 277 SKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQHISLLNRRQEERIR 336
Query: 307 LEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSLCASTLTV--S 364
+EE R + Q E++ K + +L + T L+ Q+K L V +
Sbjct: 337 EQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQEKLGEVKET 396
Query: 365 SGSSRGSLASSRGSLASSRGSLSSVSFTD 393
S++ ++RG A G SS SF D
Sbjct: 397 ETSAQKEPEAARGPGAPGPGGESS-SFMD 424
Score = 35.4 bits (80), Expect = 0.30
Identities = 49/239 (20%), Positives = 88/239 (36%), Gaps = 50/239 (20%)
Query: 10 IEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSR 69
IE R +W + +ML QE KKE KQQ +E + L K+ +
Sbjct: 237 IEGERARWHQRMSKML-------QEICTLKKE----KQQDMRRVEELERSLSKLKNQMAE 285
Query: 70 SYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKG--------- 120
+P + +E+ L L++EL ++ ELQ + K
Sbjct: 286 PLPP-----------EPPAVPSEV-----ELQHLRKELERVAGELQSQVKNNQHISLLNR 329
Query: 121 ---------VETLQEIDRKMSSTHTSYK-LDEAQAIMSELRTIKKAICTGEKERRDLMHS 170
E L++ + ++ H + L + Q++ EL K+ E++ ++L
Sbjct: 330 RQEERIREQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVKELQEK 389
Query: 171 LAKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLV 229
L ++ ++ + S P G PG G F D + + E V + R +
Sbjct: 390 LGEVKET-ETSAQKEPEAARGP---GAPGPGGESSSFMDHLKEKADLSELVKKQELRFI 444
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 48.5 bits (114), Expect = 3e-05
Identities = 77/357 (21%), Positives = 155/357 (43%), Gaps = 39/357 (10%)
Query: 8 TQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIY-----QIKQQRFELAQEEYQQLHK 62
TQ+E+ ++ + ++ L+ L V +A+ A+ E + +++ L ++ ++L
Sbjct: 1546 TQLEELEDELQATEDAKLR--LEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEA 1603
Query: 63 MCEDDSRSYA---SSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEK 119
ED+ + A +S + K QI+A +R + + +L++ QMK + E+
Sbjct: 1604 ELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEE 1663
Query: 120 GVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFK 179
+ EI + + K EA E+ +++ + + E+ RR +L D
Sbjct: 1664 ARASRDEIFAQSKESEKKLKSLEA-----EILQLQEELASSERARRHAEQERDELADEIT 1718
Query: 180 NSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYE 239
NS S +L+D + A + ++ + S +++ + F T VD + E
Sbjct: 1719 NSASGKSALLDEKRRLEA-RIAQLEEELEEEQSNMELLND-RFRKTTLQVDTLNAELAAE 1776
Query: 240 -EARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVA 298
A ++ N +QQL R + KE +A LQEL+ + + A ++
Sbjct: 1777 RSAAQKSDNARQQLERQN------------------KELKAKLQELEGAVKSKFKA-TIS 1817
Query: 299 RLEEERERLEEELRRARATSAQGATERILLQEKR-NCLLMQLEEATRLTSYLQSQLK 354
LE + +LEE+L + A A + + EK+ + MQ+E+ R + Q++
Sbjct: 1818 ALEAKIGQLEEQLEQ-EAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQME 1873
Score = 43.9 bits (102), Expect = 8e-04
Identities = 69/362 (19%), Positives = 154/362 (42%), Gaps = 44/362 (12%)
Query: 8 TQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDD 67
T+++ + R+E+E K+ +E L K+ KQ + E EE ++ H+ ++
Sbjct: 839 TKVKPLLQVTRQEEELQAKD-----EELLKVKE-----KQTKVEGELEEMERKHQQLLEE 888
Query: 68 SRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKGVETLQEI 127
A T + +++A +A+++ L + +L +E +E+ + LQ
Sbjct: 889 KNILAEQLQA-ETELFAEAEEMRARLAAKKQELEEILHDLESRVEE---EEERNQILQNE 944
Query: 128 DRKMSS--THTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDS----FKNS 181
+KM + +LDE + +L+ K T E + + + + L D K
Sbjct: 945 KKKMQAHIQDLEEQLDEEEGARQKLQLEK---VTAEAKIKKMEEEILLLEDQNSKFIKEK 1001
Query: 182 CSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEEA 241
+ D + + + + + ++ +++ + D + RL + + E+A
Sbjct: 1002 KLMEDRIAECSSQLAEEEEKA--KNLAKIRNKQEVM---ISDLEERLKKEEKTRQELEKA 1056
Query: 242 RKRV----ANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQL----IIAQRRS 293
++++ ++Q Q+A L A+ D +LQL K++E L L + + +
Sbjct: 1057 KRKLDGETTDLQDQIAELQ-------AQIDELKLQLAKKEEELQGALARGDDETLHKNNA 1109
Query: 294 AGDVARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQL 353
V L+ + L+E+ +A+ + ++ L E+ L +LE+ T T+ Q +L
Sbjct: 1110 LKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELED-TLDTTAAQQEL 1168
Query: 354 KS 355
++
Sbjct: 1169 RT 1170
Score = 40.0 bits (92), Expect = 0.012
Identities = 45/269 (16%), Positives = 112/269 (41%), Gaps = 14/269 (5%)
Query: 88 QIKAEIASRRDRLSRLKRELTQMKQELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIM 147
+I A+ +L L+ E+ Q+++EL E+ ++ +R + + A++
Sbjct: 1670 EIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQ-ERDELADEITNSASGKSALL 1728
Query: 148 SELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQF 207
E R ++ I E+E + ++ L D F+ + D+L + + + Q+
Sbjct: 1729 DEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTL-----NAELAAERSAAQKS 1783
Query: 208 CDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEEARKRVANIQQQLARLDNESWPSTAEAD 267
+A Q + + + L V+ + + ++ ++ ++ +L+ E A+
Sbjct: 1784 DNARQQLERQNKELKAKLQELEGAVK-----SKFKATISALEAKIGQLE-EQLEQEAKER 1837
Query: 268 RDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEERERLEEELRRARATSAQGATERIL 327
+L++ E L+E+ + + R D + +E+ E+ +++ + + E
Sbjct: 1838 AAANKLVRRTEKKLKEIFMQVEDERRHAD--QYKEQMEKANARMKQLKRQLEEAEEEATR 1895
Query: 328 LQEKRNCLLMQLEEATRLTSYLQSQLKSL 356
R L +L++AT L ++ +L
Sbjct: 1896 ANASRRKLQRELDDATEANEGLSREVSTL 1924
>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
Length = 2649
Score = 48.5 bits (114), Expect = 3e-05
Identities = 77/389 (19%), Positives = 158/389 (40%), Gaps = 50/389 (12%)
Query: 5 NKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKK---EIYQIKQQR---FELAQEEYQ 58
N + + +QWR E + + + + E AK E+++ ++R F+ +E+
Sbjct: 880 NNIENLISTLKQWRSEVDEKRQVFHALEDELQKAKAISDEMFKTYKERDLDFDWHKEKAD 939
Query: 59 QLHKMCED-----DSRSYASSFSGYSTNTKY--------DPHQIKAEIASRR------DR 99
QL + ++ D+R G + KY D + E R+ +
Sbjct: 940 QLVERWQNVHVQIDNR--LRDLEGIGKSLKYYRDTYHPLDDWIQQVETTQRKIQENQPEN 997
Query: 100 LSRLKRELTQMKQ---ELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKA 156
L +L Q K E++ K+ ++ Q+ + S+T Y+L + T +
Sbjct: 998 SKTLATQLNQQKMLVSEIEMKQSKMDECQKYAEQYSATVKDYEL--------QTMTYRAM 1049
Query: 157 ICTGEK---ERRDLMHSLAKLTDSFKNSCSVTDSLVDF-PHHVGVPGDA-----GVPQQF 207
+ + +K +RR + S + F + + +LV ++ GD+ +
Sbjct: 1050 VDSQQKSPVKRRRMQSSADLIIQEFMDLRTRYTALVTLMTQYIKFAGDSLKRLEEEEIKR 1109
Query: 208 CDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYEEARKRVANIQQQLARLDNESWPSTAEAD 267
C S+ + + K +++ +L + E + VA +++Q +R++ E P EA
Sbjct: 1110 CKETSEHGAYSDLLQRQKATVLENSKLTGKISELERMVAELKKQKSRVEEEL-PKVREAA 1168
Query: 268 RDRL--QLIKEKEALLQELQLIIAQRRSAGDVARLEEERERLEEELRRARATSAQGATER 325
+ L Q ++ LQ+++ ++ ++ + E+E E EL R R + + +R
Sbjct: 1169 ENELRKQQRNVEDISLQKIRAESEAKQYRRELETIVREKEAAERELERVRQLTIEAEAKR 1228
Query: 326 ILLQEKRNCLLMQLEEATRLTSYLQSQLK 354
++E QLEE T L+ LK
Sbjct: 1229 AAVEENLLNFRNQLEENTFTRRTLEDHLK 1257
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 48.5 bits (114), Expect = 3e-05
Identities = 70/335 (20%), Positives = 147/335 (43%), Gaps = 42/335 (12%)
Query: 6 KLTQIEDPREQWRREQERMLK---EYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHK 62
KL ++E +++ + ++ R ++ + L ++ L++ + Q QR A QQ +
Sbjct: 1007 KLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARR 1066
Query: 63 MCEDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKGVE 122
C++ ++ + + Y ++A L K ++++M Q+ E E
Sbjct: 1067 DCQEQAKIAVEAQNKYERELMLHAADVEA--------LQAAKEQVSKMASVRQHLE---E 1115
Query: 123 TLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGE---KERRDLMHSLAKLTDSFK 179
T Q+ + ++ S+ +E + ++ + + K +C E K+ R L + KL+D K
Sbjct: 1116 TTQKAESQLLECKASW--EERERMLKD--EVSKCVCRCEDLEKQNRLLHDQIEKLSD--K 1169
Query: 180 NSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQYE 239
SV + GV G V + SQ I+ F + + + R
Sbjct: 1170 VVASVKE---------GVQGPLNVSLSE-EGKSQEQILEILRFIRREKEIAETRFEVAQV 1219
Query: 240 EA---RKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGD 296
E+ R+RV ++++L L + + A+R+++Q+ + A +EL +
Sbjct: 1220 ESLRYRQRVELLERELQELQD-----SLNAEREKVQVTAKTMAQHEELMKKTETMNVVME 1274
Query: 297 VAR-LEEERERLEEELRRARATSAQGATERILLQE 330
+ L EE+ERLE++L++ +A + + + LQE
Sbjct: 1275 TNKMLREEKERLEQDLQQMQAKVRKLELDILPLQE 1309
Score = 31.6 bits (70), Expect = 4.3
Identities = 65/366 (17%), Positives = 140/366 (38%), Gaps = 59/366 (16%)
Query: 6 KLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEE--------- 56
++ Q+E R + R E +L+ L Q++LNA++E Q+ + +AQ E
Sbjct: 1215 EVAQVESLRYRQRVE---LLERELQELQDSLNAEREKVQVTAKT--MAQHEELMKKTETM 1269
Query: 57 --YQQLHKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQEL 114
+ +KM ++ + +++ +I ++ + L + ++ E
Sbjct: 1270 NVVMETNKMLREEKERLEQDLQQMQAKVR----KLELDILPLQEANAELSEKSGMLQAEK 1325
Query: 115 QYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSLAKL 174
+ E+ V+ + ++ + S +E + ++SE K I +E L +A+
Sbjct: 1326 KLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARS 1385
Query: 175 TDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFV-FDDKTRLVDRV- 232
S N+ ++ SL + + V + Q D+ + + +K + + +V
Sbjct: 1386 NASLTNNQNLIQSLKEDLNKVRTEKET----------IQKDLDAKIIDIQEKVKTITQVK 1435
Query: 233 ----RLNWQYEEARKRVANIQQQLARLDN----------------------ESWPSTAEA 266
R QYEE + + + + A+ E+ + E+
Sbjct: 1436 KIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLES 1495
Query: 267 DRDRLQ-LIKEKEALLQELQLIIAQRRSAGDVARLEEERERLEEELRRARATSAQGATER 325
+ LQ + EKE + LQ Q +S R + + +EE R + T + T +
Sbjct: 1496 QVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRK 1555
Query: 326 ILLQEK 331
++ K
Sbjct: 1556 AIVAAK 1561
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 48.5 bits (114), Expect = 3e-05
Identities = 58/270 (21%), Positives = 121/270 (44%), Gaps = 21/270 (7%)
Query: 88 QIKAE---IASRRDRLSRLKRELTQMKQELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQ 144
Q++AE +A +R L + Q++ +++ + +E +E++ +++ + DE
Sbjct: 939 QLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLE-DECT 997
Query: 145 AIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVP 204
+ ++ +K + EKE++ + + LT+ ++ +S+ +A
Sbjct: 998 ELKKDIDDLKLTLAKAEKEKQATENKVKNLTEEM---AALDESVARLTKEKKALQEAH-Q 1053
Query: 205 QQFCDAGSQTDIIGEFVFDDKTRLVDRVR-LNWQYEEARKRVANIQQQLARLDNE---SW 260
Q D ++ D + K RL +V L E+ +K + ++ +L+ + +
Sbjct: 1054 QALGDLQAEEDRVSALT-KAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQ 1112
Query: 261 PSTAEADRDRLQL---IKEKEALLQELQLIIAQRRSAG-----DVARLEEERERLEEELR 312
S A+A +D+ QL +K+K++ L +L L + + G + L+ E LEEEL
Sbjct: 1113 ESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELE 1172
Query: 313 RARATSAQGATERILLQEKRNCLLMQLEEA 342
RA A+ +R + L +LEEA
Sbjct: 1173 AERAARARVEKQRAEAARELEELSERLEEA 1202
Score = 38.5 bits (88), Expect = 0.035
Identities = 66/289 (22%), Positives = 117/289 (40%), Gaps = 44/289 (15%)
Query: 91 AEIASRRDRLSRLKRELTQMKQELQYK----EKGVETLQEIDRKMSSTHTSYKLDEAQAI 146
AE+ + D L R++++L + K EL+ + VETL +Y+ D+
Sbjct: 1250 AELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYE-DQLSEA 1308
Query: 147 MSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQ 206
++ +++ + +R L +L+ + + L G A Q
Sbjct: 1309 KIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSR--------GKALAAQS 1360
Query: 207 FCDAGSQTDIIGEFVFDDKTRLVDRVR--------LNWQYEEARKRVANIQQQLARLDNE 258
+ Q + + K+ L V+ L Q+EE + A +Q+ L++ + E
Sbjct: 1361 LEELRRQLEEESKA----KSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAE 1416
Query: 259 --SWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVAR-----LEEERERLEEE- 310
W S EAD +Q +E E ++L L + + + A LE+ + RL+ E
Sbjct: 1417 VAQWRSKYEADA--IQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTES 1474
Query: 311 ----LRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKS 355
L RATSA A L +K+ L LEE R +Q +L++
Sbjct: 1475 EDVTLELERATSAAAA-----LDKKQRHLERALEERRRQEEEMQRELEA 1518
Score = 35.0 bits (79), Expect = 0.39
Identities = 75/380 (19%), Positives = 150/380 (39%), Gaps = 44/380 (11%)
Query: 5 NKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMC 64
NK+ + + R+ KE + QEA Q ++ R + +L +
Sbjct: 1022 NKVKNLTEEMAALDESVARLTKEKKAL-QEAHQQALGDLQAEEDRVSALTKAKLRLEQQV 1080
Query: 65 EDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKGVE-- 122
ED S +T+ +++ ++ ++ ++ ++ Q++++L+ K+ +
Sbjct: 1081 EDLECSLEQE-KKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQL 1139
Query: 123 TLQEIDRKMSSTHTSYKLDEAQA----IMSELRTIKKAICTGEKERRDLMHSLAKLTDSF 178
+L+ D ++ K+ E QA + EL + A EK+R + L +L++
Sbjct: 1140 SLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERL 1199
Query: 179 KNS----------CSVTDS----LVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDD 224
+ + C ++ L + +A V +GE V D
Sbjct: 1200 EEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQV-DS 1258
Query: 225 KTRLVDRVRLNWQYEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQEL 284
R+ R +L + E R V ++ + L S + R + E + ++EL
Sbjct: 1259 LQRV--RQKLEKEKSELRMEVDDLAANVETLTRAK-ASAEKLCRTYEDQLSEAKIKVEEL 1315
Query: 285 QLIIAQ--------RRSAGDVARLEEERERLEEELRRARATSAQGATERILLQEKRNCLL 336
Q +A + +G+++RL EE+E L +L R +A +AQ E L
Sbjct: 1316 QRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEE----------LR 1365
Query: 337 MQLEEATRLTSYLQSQLKSL 356
QLEE ++ S L +++L
Sbjct: 1366 RQLEEESKAKSALAHAVQAL 1385
Score = 31.2 bits (69), Expect = 5.6
Identities = 72/350 (20%), Positives = 137/350 (39%), Gaps = 57/350 (16%)
Query: 6 KLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQ------QRFELAQEEYQQ 59
K +E E+ RR++E M +E +E+ E+++++ + E + E +
Sbjct: 1494 KQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKN 1553
Query: 60 LHKMCED--DSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLS-----------RLKRE 106
L + D D S + TK K+EI + + R++ E
Sbjct: 1554 LQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLE 1613
Query: 107 LTQMKQELQYKEKGVETLQEIDRKMSSTHTSYK--LDEAQAIM-SELRTIKKAICTGEKE 163
L+Q+K E+ K L E D + ++ +++ ++ QA + +E R +A+ +K
Sbjct: 1614 LSQVKAEVDRK------LAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKM 1667
Query: 164 RRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFD 223
DL D + H +A + A + + G D
Sbjct: 1668 EGDL-----------------NDLELQLGHATRQATEAQAATRLMQAQLKEEQAGR---D 1707
Query: 224 DKTRLVDRVRLNWQYEEARKRV--ANIQQQLARLDN-ESWPSTAEAD----RDRLQLIKE 276
++ RL + Q E R + A +++ A L+ E AE + +RL L+
Sbjct: 1708 EEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHS 1767
Query: 277 KEA--LLQELQLIIAQRRSAGDVARLEEERERLEEELRRARATSAQGATE 324
+ L Q+ +L + +G+V +ER EE+ ++A +A A E
Sbjct: 1768 QNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEE 1817
>gi|113425145 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 3 [Homo sapiens]
Length = 632
Score = 48.1 bits (113), Expect = 4e-05
Identities = 59/290 (20%), Positives = 120/290 (41%), Gaps = 27/290 (9%)
Query: 87 HQIKAEIASRRDRLSRLKRELTQMKQELQYKEKGVET-LQEIDRKM-----SSTHTSYKL 140
HQ++ E + +R + +REL Q L +++ + T L ++R + S + +L
Sbjct: 112 HQLEEEKKANNER-QKAERELEVQIQTLIIQKEELNTDLYHMERSLRYFEEESKDLAVRL 170
Query: 141 DEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGD 200
+ EL + A+ EK++ + + S +K ++ S+ D + +
Sbjct: 171 QHSLQCKGELESALSAVIATEKKKANQLSSCSKAHTEWELEQSLQDQALLKAQLTQLK-- 228
Query: 201 AGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVR--------LNWQYEEARKRVANIQQQL 252
+ F + D E + ++ R R+ L + ++ +RV +++ L
Sbjct: 229 ----ESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKEKQQDMRRVEELERSL 284
Query: 253 ARLDNESW------PSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEERER 306
++L N+ P ++ + L KE E + ELQ + + + R +EER R
Sbjct: 285 SKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQHISLLNRRQEERIR 344
Query: 307 LEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSL 356
+EE R + Q E++ K + +L + T L+ Q+K L
Sbjct: 345 EQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVKEL 394
>gi|113425137 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 3 [Homo sapiens]
Length = 632
Score = 48.1 bits (113), Expect = 4e-05
Identities = 59/290 (20%), Positives = 120/290 (41%), Gaps = 27/290 (9%)
Query: 87 HQIKAEIASRRDRLSRLKRELTQMKQELQYKEKGVET-LQEIDRKM-----SSTHTSYKL 140
HQ++ E + +R + +REL Q L +++ + T L ++R + S + +L
Sbjct: 112 HQLEEEKKANNER-QKAERELEVQIQTLIIQKEELNTDLYHMERSLRYFEEESKDLAVRL 170
Query: 141 DEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGD 200
+ EL + A+ EK++ + + S +K ++ S+ D + +
Sbjct: 171 QHSLQCKGELESALSAVIATEKKKANQLSSCSKAHTEWELEQSLQDQALLKAQLTQLK-- 228
Query: 201 AGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVR--------LNWQYEEARKRVANIQQQL 252
+ F + D E + ++ R R+ L + ++ +RV +++ L
Sbjct: 229 ----ESFQQLQLERDECAEHIEGERARWHQRMSKMSQEICTLKKEKQQDMRRVEELERSL 284
Query: 253 ARLDNESW------PSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEERER 306
++L N+ P ++ + L KE E + ELQ + + + R +EER R
Sbjct: 285 SKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQHISLLNRRQEERIR 344
Query: 307 LEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSL 356
+EE R + Q E++ K + +L + T L+ Q+K L
Sbjct: 345 EQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVKEL 394
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 48.1 bits (113), Expect = 4e-05
Identities = 93/429 (21%), Positives = 170/429 (39%), Gaps = 61/429 (14%)
Query: 2 DHINKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEI----YQIKQQRFELAQEEY 57
DH +L + RE RE++ LK+ + +E AK EI Q+ + + AQ
Sbjct: 580 DHAQQLATAAEEREASLRERDAALKQLEALEKEKA-AKLEILQQQLQVANEARDSAQTSV 638
Query: 58 QQLHKMCEDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYK 117
Q + + SR + + H+ +A++A +L +++ T+ ++ Q K
Sbjct: 639 TQAQREKAELSRK-VEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEK 697
Query: 118 EKGVETLQEIDRKMSSTHTSYK---------LDEAQAIMSELRTIKKAICTGEKE----- 163
++ E LQ + + T S + L+E Q +SEL+ +++ K
Sbjct: 698 DQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKEL 757
Query: 164 ------RRDLMHSLAKLTDSFKNSCSV----------TDSLVDFPHHVGVPGDAGVPQQF 207
R+ L L +L ++ + V + V A +++
Sbjct: 758 EEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERY 817
Query: 208 CDAGSQTDIIGEFVFDDKTRLVDRV-RLNWQYEEARKRVANIQQ----QLARLDNESWPS 262
D+ + G + L + + + +EA+++VA I+ Q++R NE
Sbjct: 818 EDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAEL 877
Query: 263 TAEADRDRLQLIKEKEALLQEL--QLIIAQRRSAG---DVARLE-------EERERLEEE 310
A R LQ ++EKE Q+L L Q + A +VARLE E++E E
Sbjct: 878 HANLAR-ALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRE 936
Query: 311 LRRARATSAQGATERILLQEKRNCLLMQ--LEEATRLTSYLQSQLKSLCASTLTVSSGSS 368
L + A + E + Q+ R Q L+ R + ++L+ L A+ + S
Sbjct: 937 LVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALM-----ES 991
Query: 369 RGSLASSRG 377
+G RG
Sbjct: 992 QGQQQEERG 1000
Score = 45.8 bits (107), Expect = 2e-04
Identities = 87/420 (20%), Positives = 162/420 (38%), Gaps = 60/420 (14%)
Query: 15 EQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEE---------YQQLHKMCE 65
E+ RR + + ++ +++ + + Q K++R EL +E QQL + +
Sbjct: 720 EEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQ 779
Query: 66 DDS----RSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYK---- 117
++ R A + + T + + Q+ E+A+ R+R ++E Q Q +
Sbjct: 780 AETEVLRRELAEAMAAQHT-AESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTL 838
Query: 118 ----EKGVETLQEIDRKMSS--THTSYKLDEAQAIMSELRTIKKAICTGEKERRDLMHSL 171
EK + LQE K++ +H+ ++ Q ++EL +E+ L
Sbjct: 839 KEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKL 898
Query: 172 AKLTDSFKNSCSVTDSLVDFPHHVGVPGDAGVPQQFCDAGSQTDIIGEFVFDDKTRLVDR 231
A + + + T V A + AG Q + + + R DR
Sbjct: 899 ADDLSTLQEKMAATSKEV-----------ARLETLVRKAGEQQETASRELVKEPARAGDR 947
Query: 232 VRLNWQYEEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQR 291
+ W E+ ++ + Q L ++ E+ E +R R L++ + +E +
Sbjct: 948 -QPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEE------RG 1000
Query: 292 RSAGDVARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQS 351
+ +VARL +ER R + +L +A A+ L M+L+ A +
Sbjct: 1001 QQEREVARLTQERGRAQADLALEKAARAE--------------LEMRLQNALNEQRVEFA 1046
Query: 352 QLKSLCASTLTVSSGSSRGSLASSRGSLASSRGSLSSVSFTDIY---GLPQYEKPDAEGS 408
L+ A LT G + LA RG A+ L + T L + EK A GS
Sbjct: 1047 TLQEALAHALTEKEGKDQ-ELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGS 1105
Score = 42.7 bits (99), Expect = 0.002
Identities = 74/383 (19%), Positives = 158/383 (41%), Gaps = 63/383 (16%)
Query: 4 INKLTQIEDPREQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKM 63
+ +L E + Q E+ R+L+ A+ A N+ + +R +EE Q L +
Sbjct: 1251 LKRLVMAESEKSQKLEERLRLLQ-----AETASNSARAA-----ERSSALREEVQSLRE- 1299
Query: 64 CEDDSRSYASSFSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYKEKGVET 123
E + + AS ++ E+ S+ +R L +EL +++ KE+ + T
Sbjct: 1300 -EAEKQRVASE-------------NLRQELTSQAERAEELGQELKAWQEKFFQKEQALST 1345
Query: 124 LQ--------EIDRKMSSTHTSYKLDEAQAI-----MSELRTIKKA-------ICTGEKE 163
LQ + + + H +L QA EL K+A + ++E
Sbjct: 1346 LQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRE 1405
Query: 164 RRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGDAG--VPQQFCDAGSQTDIIGEFV 221
+L+ K+ + + + + + + + A + ++ G + ++ +F+
Sbjct: 1406 LGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFL 1465
Query: 222 FDDKTRLVDRVRLNWQYE------EARKRVANIQQQLARLDNESWPSTAEADRDRLQLIK 275
+ +D+ R + E +A R+A +Q++ E TA+ + ++++++
Sbjct: 1466 EVE----LDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLE 1521
Query: 276 EKEALLQELQLIIAQRRSAGDVARLEEERERLEEELRRARATSAQGATERILLQEKRNCL 335
E++ +E Q + AQ + + E+ + EEL + A S Q + + Q+K +
Sbjct: 1522 ERQRFQEERQKLTAQ---VEQLEVFQREQTKQVEELSKKLADSDQASK---VQQQKLKAV 1575
Query: 336 LMQLEEATRLTSYLQSQLKSLCA 358
Q E+ + LQ+QL L A
Sbjct: 1576 QAQGGESQQEAQRLQAQLNELQA 1598
Score = 40.4 bits (93), Expect = 0.009
Identities = 84/414 (20%), Positives = 171/414 (41%), Gaps = 65/414 (15%)
Query: 2 DHINKLTQIEDPREQ-WRREQERMLKEYLIVAQE--ALNAKKEIYQIKQQRFEL------ 52
D +N+LT+ Q W +Q ++ KE Q+ L K EI Q K + E
Sbjct: 339 DALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQ 398
Query: 53 ---AQEEYQQLHKMCEDDS-RSYASSFSGYSTNTKY-------DPHQIKAEIASRRDRLS 101
QE+ + L + + ++ + A++ + +T + + Q +A++ + R
Sbjct: 399 DNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFE 458
Query: 102 RLKRELTQMKQELQYKEKGVETLQEIDRKMSSTHTSYKLDEAQAIMSELRTIKKAICTGE 161
K++L+ + +LQ + +E + S H + + ++ SEL T+ I +
Sbjct: 459 EEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQD 518
Query: 162 KE----RRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGDA--GVPQQFCDAGSQTD 215
+E ++ A+L + + + L H V + QQ + + +
Sbjct: 519 QELAGLKQQAKEKQAQLAQTLQQQEQASQGL---RHQVEQLSSSLKQKEQQLKEVAEKQE 575
Query: 216 I--------IGEFVFDDKTRLVDRVRLNWQYEEARKRVA---NIQQQLARLDNE----SW 260
+ + + L +R Q E K A I QQ ++ NE +
Sbjct: 576 ATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQ 635
Query: 261 PSTAEADRDRLQLIK-----------------EKEALLQELQL-IIAQRRSAGDVARLEE 302
S +A R++ +L + E +A + EL+L + ++++ A + R+ +
Sbjct: 636 TSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQ 695
Query: 303 ERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSL 356
E+++L+E+L+ + + T+ L +EKR LEE R S L+++ +SL
Sbjct: 696 EKDQLQEQLQALK--ESLKVTKGSLEEEKRRA-ADALEEQQRCISELKAETRSL 746
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 47.8 bits (112), Expect = 6e-05
Identities = 71/362 (19%), Positives = 142/362 (39%), Gaps = 46/362 (12%)
Query: 15 EQWRREQERMLKEYLIVAQEALNAKKEIYQIKQQRFELAQEEYQQLHKMCEDDSRSYASS 74
E+ R + R L+E +EA A ++ ++R + E+Q++ + E+ + + ++
Sbjct: 1135 EKLRSDLSRELEEISERLEEAGGATSVQIEMNKKR----EAEFQKMRRDLEEATLQHEAT 1190
Query: 75 FSGYSTNTKYDPHQIKAEIASRRDRLSRLKRELTQMKQELQYK-----------EKGVET 123
+ AE+ + D L R+K++L + K E + + K
Sbjct: 1191 AAALRKKHA----DSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKAN 1246
Query: 124 LQEIDRKMSSTHTSY--KLDEAQAIMSELRTIKKAICTGEKE-RRDLMHSLAKLTDSFKN 180
L+++ R + Y KL+EAQ +++ T + + T E R L A ++ +
Sbjct: 1247 LEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRG 1306
Query: 181 SCSVTDSLVDFPHHVGVPGDA--GVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVRLNWQY 238
S T + D + G A + A D++ E QY
Sbjct: 1307 KLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLRE-----------------QY 1349
Query: 239 EEARKRVANIQQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDV- 297
EE + A +Q+ L++ ++E + + D +Q +E E ++L + A +
Sbjct: 1350 EEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAV 1409
Query: 298 ----ARLEEERERLEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQL 353
+ LE+ + RL+ E+ + L +K+ L E + QS+L
Sbjct: 1410 NAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSEL 1469
Query: 354 KS 355
+S
Sbjct: 1470 ES 1471
Score = 38.5 bits (88), Expect = 0.035
Identities = 54/280 (19%), Positives = 116/280 (41%), Gaps = 21/280 (7%)
Query: 85 DPHQIKAEIASRRDRLSRLKRELTQM---KQELQYKEKGVETLQEIDRKMSSTHTSYKL- 140
+ + ++ ++ + +D L+ + Q+ K +L+ K K + E + +M++ T+ K
Sbjct: 885 EKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRK 944
Query: 141 --DEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPH----- 193
DE + ++ ++ + EKE+ + + LT+ + L
Sbjct: 945 LEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEA 1004
Query: 194 HVGVPGDAGVPQQFCDAGSQTDIIGEFVFDD-KTRLVDRVRLNWQYEEARKRVAN----I 248
H D V + ++ S++ + E DD + L ++ E A++++
Sbjct: 1005 HQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 1064
Query: 249 QQQLARLDNESWPSTAEADRDRLQLIKEKEALLQELQLIIA-QRRSAGDVARLEEERERL 307
Q+ + L+N+ + + + ++ + E L + Q++ + AR+EE L
Sbjct: 1065 QESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEE----L 1120
Query: 308 EEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTS 347
EEEL R A+ R L + + +LEEA TS
Sbjct: 1121 EEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATS 1160
>gi|113425121 PREDICTED: similar to Golgin subfamily A member 8-like
protein 2 isoform 4 [Homo sapiens]
Length = 632
Score = 47.4 bits (111), Expect = 8e-05
Identities = 59/290 (20%), Positives = 119/290 (41%), Gaps = 27/290 (9%)
Query: 87 HQIKAEIASRRDRLSRLKRELTQMKQELQYKEKGVET-LQEIDRKM-----SSTHTSYKL 140
HQ++ E + +R + +REL Q L +++ + T L ++R + S + +L
Sbjct: 112 HQLEEEKKANNER-QKAERELEVQIQTLIIQKEELNTDLYHMERSLRYFEEESKDLAVRL 170
Query: 141 DEAQAIMSELRTIKKAICTGEKERRDLMHSLAKLTDSFKNSCSVTDSLVDFPHHVGVPGD 200
+ EL A+ EK++ + + S +K ++ S+ D + +
Sbjct: 171 QHSLQCKGELERALSAVIATEKKKANQLSSCSKAHTEWELEQSLQDQALLKAQLTQLK-- 228
Query: 201 AGVPQQFCDAGSQTDIIGEFVFDDKTRLVDRVR--------LNWQYEEARKRVANIQQQL 252
+ F + D E + ++ R R+ L + ++ +RV +++ L
Sbjct: 229 ----ESFQQLQLERDECAEHIEGERARWHQRMSKMLQEICTLKKEKQQDMRRVEELERSL 284
Query: 253 ARLDNESW------PSTAEADRDRLQLIKEKEALLQELQLIIAQRRSAGDVARLEEERER 306
++L N+ P ++ + L KE E + ELQ + + + R +EER R
Sbjct: 285 SKLKNQMAEPLPPEPPAVPSEVELQHLRKELERVAGELQSQVKNNQHISLLNRRQEERIR 344
Query: 307 LEEELRRARATSAQGATERILLQEKRNCLLMQLEEATRLTSYLQSQLKSL 356
+EE R + Q E++ K + +L + T L+ Q+K L
Sbjct: 345 EQEERLRKQEERLQEQHEKLRQLAKPQSVFEELNNENKSTLQLEQQVKEL 394
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,629,197
Number of Sequences: 37866
Number of extensions: 2142463
Number of successful extensions: 13901
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 642
Number of HSP's that attempted gapping in prelim test: 10591
Number of HSP's gapped (non-prelim): 3622
length of query: 1092
length of database: 18,247,518
effective HSP length: 113
effective length of query: 979
effective length of database: 13,968,660
effective search space: 13675318140
effective search space used: 13675318140
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.