Search of human proteins with 38505222

Search of human proteins with 38505222

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38505222 thioredoxin domain containing 10 [Homo sapiens]
         (454 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38505222 thioredoxin domain containing 10 [Homo sapiens]           917   0.0  
gi|4758304 protein disulfide isomerase A4 [Homo sapiens]              103   2e-22
gi|5031973 protein disulfide isomerase A6 [Homo sapiens]               98   1e-20
gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo s...    94   2e-19
gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]    91   2e-18
gi|42794771 thioredoxin domain containing 5 isoform 1 precursor ...    82   8e-16
gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo sap...    74   4e-13
gi|94966757 protein disulfide isomerase A2 [Homo sapiens]              69   1e-11
gi|151101292 thioredoxin domain containing 1 [Homo sapiens]            69   1e-11
gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo s...    62   1e-09
gi|5803121 protein disulfide isomerase A5 [Homo sapiens]               59   9e-09
gi|145580631 quiescin Q6 sulfhydryl oxidase 2 [Homo sapiens]           52   1e-06
gi|52487191 thioredoxin domain containing 4 (endoplasmic reticul...    52   1e-06
gi|51873067 quiescin Q6 sulfhydryl oxidase 1 isoform b [Homo sap...    52   1e-06
gi|13325075 quiescin Q6 sulfhydryl oxidase 1 isoform a [Homo sap...    52   1e-06
gi|227430327 calsequestrin 1 [Homo sapiens]                            50   3e-06
gi|40254947 thioredoxin-related transmembrane protein 4 [Homo sa...    48   2e-05
gi|21361403 thioredoxin 2 precursor [Homo sapiens]                     47   5e-05
gi|119395727 cardiac calsequestrin 2 precursor [Homo sapiens]          46   8e-05
gi|221136993 thioredoxin domain containing 14 isoform 2 [Homo sa...    42   9e-04
gi|7705726 thioredoxin domain containing 14 isoform 1 [Homo sapi...    42   9e-04
gi|56687498 DnaJ (Hsp40) homolog, subfamily C, member 16 [Homo s...    42   0.001
gi|94421469 disulfide isomerase [Homo sapiens]                         40   0.003
gi|50592994 thioredoxin [Homo sapiens]                                 39   0.007
gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sap...    38   0.022
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap...    38   0.022
gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapi...    38   0.022
gi|28372543 protein disulfide isomerase-like, testis expressed [...    34   0.31 
gi|148839372 thioredoxin domain containing 3 [Homo sapiens]            32   1.2  
gi|54633317 thioredoxin domain containing 11 [Homo sapiens]            32   1.6  

>gi|38505222 thioredoxin domain containing 10 [Homo sapiens]
          Length = 454

 Score =  917 bits (2369), Expect = 0.0
 Identities = 454/454 (100%), Positives = 454/454 (100%)

Query: 1   MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLE 60
           MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLE
Sbjct: 1   MAAWKSWTALRLCATVVVLDMVVCKGFVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLE 60

Query: 61  PIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKD 120
           PIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKD
Sbjct: 61  PIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKD 120

Query: 121 DIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYF 180
           DIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYF
Sbjct: 121 DIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYF 180

Query: 181 FSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLAMDGFLLY 240
           FSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLAMDGFLLY
Sbjct: 181 FSASEEVVPEYVTLKEMPAVLVFKDETYFVYDEYEDGDLSSWINRERFQNYLAMDGFLLY 240

Query: 241 ELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLL 300
           ELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLL
Sbjct: 241 ELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGNDYINTLL 300

Query: 301 MDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQFINNILDGTVEAQGGDSILQRLKRIV 360
           MDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQFINNILDGTVEAQGGDSILQRLKRIV
Sbjct: 301 MDELTVPTVVVLNTSNQQYFLLDRQIKNVEDMVQFINNILDGTVEAQGGDSILQRLKRIV 360

Query: 361 FDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSENENQ 420
           FDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSENENQ
Sbjct: 361 FDAKSTIVSIFKSSPLMGCFLFGLPLGVISIMCYGIYTADTDGGYIEERYEVSKSENENQ 420

Query: 421 EQIEESKEQQEPSSGGSVVPTVQEPKDVLEKKKD 454
           EQIEESKEQQEPSSGGSVVPTVQEPKDVLEKKKD
Sbjct: 421 EQIEESKEQQEPSSGGSVVPTVQEPKDVLEKKKD 454


>gi|4758304 protein disulfide isomerase A4 [Homo sapiens]
          Length = 645

 Score =  103 bits (258), Expect = 2e-22
 Identities = 57/146 (39%), Positives = 84/146 (57%), Gaps = 4/146 (2%)

Query: 33  ESFKENRND-DIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIA 91
           E+F E  ND DI LV+FYAPWCGHCKKL P + +   E+     P+ + K+DAT+ + +A
Sbjct: 185 ENFDEVVNDADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLA 244

Query: 92  SEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRP-LPSQQMFEHMQKRH 150
             F V GYPT+K+ +    Y+Y GPR K  I+++    SG   +  L  +Q+ E ++   
Sbjct: 245 KRFDVSGYPTLKIFRKGRPYDYNGPREKYGIVDYMIEQSGPPSKEILTLKQVQEFLKDGD 304

Query: 151 RVFF--VYVGGESPLKEKYIDAASEL 174
            V    V+ G   P  ++Y DAA+ L
Sbjct: 305 DVIIIGVFKGESDPAYQQYQDAANNL 330



 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 42/89 (47%), Positives = 58/89 (65%)

Query: 42  DIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPT 101
           D  L++FYAPWCGHCK+  P + ++   +K    P+ V K+DATS S +AS F V GYPT
Sbjct: 80  DTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPT 139

Query: 102 IKLLKGDLAYNYRGPRTKDDIIEFAHRVS 130
           IK+LK   A +Y G RT+++I+     VS
Sbjct: 140 IKILKKGQAVDYEGSRTQEEIVAKVREVS 168



 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 27/58 (46%), Positives = 39/58 (67%), Gaps = 1/58 (1%)

Query: 45  LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTI 102
           L++FYAPWCGHCK+LEP++N +  + K     V + KMDAT+    +  + V G+PTI
Sbjct: 547 LIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLV-IAKMDATANDVPSDRYKVEGFPTI 603


>gi|5031973 protein disulfide isomerase A6 [Homo sapiens]
          Length = 440

 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 48/106 (45%), Positives = 68/106 (64%), Gaps = 4/106 (3%)

Query: 25  KGFVEDLDESFKEN--RNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMK-SIGSPVKVGK 81
           K  +E  D+SF +N   ++D+W+V+FYAPWCGHCK LEP W     E+K      VK+  
Sbjct: 160 KDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAA 219

Query: 82  MDATSYSSIASEFGVRGYPTIKLL-KGDLAYNYRGPRTKDDIIEFA 126
           +DAT    +AS +G+RG+PTIK+  KG+   +Y G RT+ DI+  A
Sbjct: 220 VDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVSRA 265



 Score = 85.9 bits (211), Expect = 7e-17
 Identities = 46/128 (35%), Positives = 73/128 (57%), Gaps = 20/128 (15%)

Query: 16  VVVLDMVVCKGFV---------EDLDESFKENRN------DDIWLVDFYAPWCGHCKKLE 60
           ++VL +V C  F+         +D+ E    N N      D +WLV+FYAPWCGHC++L 
Sbjct: 3   LLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLT 62

Query: 61  PIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLL--KGDLAYNYRGPRT 118
           P W +    +K +   VKVG +DA  + S+  ++GV+G+PTIK+     +   +Y+G RT
Sbjct: 63  PEWKKAATALKDV---VKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRT 119

Query: 119 KDDIIEFA 126
            + I++ A
Sbjct: 120 GEAIVDAA 127


>gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo
           sapiens]
          Length = 508

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 55/165 (33%), Positives = 91/165 (55%), Gaps = 7/165 (4%)

Query: 45  LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 104
           LV+FYAPWCGHCK L P + +   ++K+ GS +++ K+DAT  S +A ++GVRGYPTIK 
Sbjct: 45  LVEFYAPWCGHCKALAPEYAKAAGKLKAEGSEIRLAKVDATEESDLAQQYGVRGYPTIKF 104

Query: 105 LK-GDLA--YNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRVFFV--YVGG 159
            + GD A    Y   R  DDI+ +  + +G     LP     E + +   V  +  +   
Sbjct: 105 FRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVESSEVAVIGFFKDV 164

Query: 160 ESPLKEKYIDAASELIVYTYFFSASEEVVPEYVTLKEMPAVLVFK 204
           ES   ++++ AA  +    +  +++ +V  +Y   K+   V++FK
Sbjct: 165 ESDSAKQFLQAAEAIDDIPFGITSNSDVFSKYQLDKD--GVVLFK 207



 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 36/97 (37%), Positives = 52/97 (53%), Gaps = 9/97 (9%)

Query: 32  DESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIA 91
           D +F E +N     V+FYAPWCGHCK+L PIW+++G   K     + + KMD+T+    A
Sbjct: 379 DVAFDEKKNV---FVEFYAPWCGHCKQLAPIWDKLGETYKD-HENIVIAKMDSTANEVEA 434

Query: 92  SEFGVRGYPTIKLLKGD---LAYNYRGPRTKDDIIEF 125
            +  V  +PT+K           +Y G RT D   +F
Sbjct: 435 VK--VHSFPTLKFFPASADRTVIDYNGERTLDGFKKF 469


>gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]
          Length = 505

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 83/360 (23%), Positives = 161/360 (44%), Gaps = 38/360 (10%)

Query: 9   ALRLCATVVVLDMVVCKGFVEDLDESFKENRNDD----IWLVDFYAPWCGHCKKLEPIWN 64
           A RL A   VL++          D++F+   +D     + LV+F+APWCGHCK+L P + 
Sbjct: 18  AARLAAASDVLELT---------DDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYE 68

Query: 65  EVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLK-GDLAYNYRGPRTKDDII 123
                +K I   V + K+D T+ ++  +++GV GYPT+K+ + G+ A  Y GPRT D I+
Sbjct: 69  AAATRLKGI---VPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIV 125

Query: 124 EFAHRVSGALIRPLPSQQMFEHM--QKRHRVFFVYVGGESPLKEKYIDAASEL-IVYTYF 180
               + +G    PL +++ F+     K   +   +    S    +++ AAS L   Y + 
Sbjct: 126 SHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFA 185

Query: 181 FSASEEVVPEY-------VTLKEMPAVLVFKDETY-FVYDEYEDGDLSSWINRERFQ--N 230
            +  E +V EY       +  +       F+D+T  +   +   G +  +I    F    
Sbjct: 186 HTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENIFGICP 245

Query: 231 YLAMDGFLLYELGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHM 290
           ++  D   L +  D   L+A   +D +  +      ++ +  VA+ + D  H+   F   
Sbjct: 246 HMTEDNKDLIQGKDL--LIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHK-LNFAVA 302

Query: 291 DGNDYINTLLMDEL-----TVPTVVVLNTSNQQYFLLDRQIKNVEDMVQFINNILDGTVE 345
               + + L    L      +P V +     +++ + +   ++ + + +F+ +  DG ++
Sbjct: 303 SRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGNLK 362



 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 43/103 (41%), Positives = 58/103 (56%), Gaps = 7/103 (6%)

Query: 29  EDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYS 88
           E+ DE    N N D+ L++FYAPWCGHCK LEP + E+G E  S    + + KMDAT+ +
Sbjct: 384 ENFDE-IVNNENKDV-LIEFYAPWCGHCKNLEPKYKELG-EKLSKDPNIVIAKMDATA-N 439

Query: 89  SIASEFGVRGYPTIKLLKGDLAYN---YRGPRTKDDIIEFAHR 128
            + S + VRG+PTI     +   N   Y G R   D I +  R
Sbjct: 440 DVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQR 482


>gi|42794771 thioredoxin domain containing 5 isoform 1 precursor
           [Homo sapiens]
          Length = 432

 Score = 82.4 bits (202), Expect = 8e-16
 Identities = 38/74 (51%), Positives = 53/74 (71%), Gaps = 2/74 (2%)

Query: 46  VDFYAPWCGHCKKLEPIWNEVGLEMKSI-GSPVKVGKMDATSYSSIASEFGVRGYPTIKL 104
           V F+APWCGHC++L+P WN++G +  S+  + V V K+D T++S + S  GVRGYPT+KL
Sbjct: 82  VMFFAPWCGHCQRLQPTWNDLGDKYNSMEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKL 141

Query: 105 LK-GDLAYNYRGPR 117
            K G  A  Y+GPR
Sbjct: 142 FKPGQEAVKYQGPR 155



 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 41/114 (35%), Positives = 62/114 (54%), Gaps = 2/114 (1%)

Query: 14  ATVVVLDMVVCKGFVEDLDES-FKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKS 72
           A V+  +    KG V  L E+ F +   + I  + FYAPWCGHCK L P W E+  +   
Sbjct: 310 APVLAAEPEADKGTVLALTENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFP 369

Query: 73  IGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYN-YRGPRTKDDIIEF 125
             + VK+ ++D T+  +I S++ VRGYPT+ L +G    + + G R  D +  F
Sbjct: 370 GLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRF 423



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 31/81 (38%), Positives = 47/81 (58%), Gaps = 2/81 (2%)

Query: 46  VDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLL 105
           + F+APWCGHCK L P W ++ L ++     VK+GK+D T +  + S   VRGYPT+   
Sbjct: 210 IKFFAPWCGHCKALAPTWEQLALGLEH-SETVKIGKVDCTQHYELCSGNQVRGYPTLLWF 268

Query: 106 K-GDLAYNYRGPRTKDDIIEF 125
           + G     Y+G R  + + E+
Sbjct: 269 RDGKKVDQYKGKRDLESLREY 289


>gi|224493972 thioredoxin domain containing 5 isoform 3 [Homo
           sapiens]
          Length = 324

 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 41/114 (35%), Positives = 62/114 (54%), Gaps = 2/114 (1%)

Query: 14  ATVVVLDMVVCKGFVEDLDES-FKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKS 72
           A V+  +    KG V  L E+ F +   + I  + FYAPWCGHCK L P W E+  +   
Sbjct: 202 APVLAAEPEADKGTVLALTENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFP 261

Query: 73  IGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYN-YRGPRTKDDIIEF 125
             + VK+ ++D T+  +I S++ VRGYPT+ L +G    + + G R  D +  F
Sbjct: 262 GLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRF 315



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 31/81 (38%), Positives = 47/81 (58%), Gaps = 2/81 (2%)

Query: 46  VDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLL 105
           + F+APWCGHCK L P W ++ L ++     VK+GK+D T +  + S   VRGYPT+   
Sbjct: 102 IKFFAPWCGHCKALAPTWEQLALGLEH-SETVKIGKVDCTQHYELCSGNQVRGYPTLLWF 160

Query: 106 K-GDLAYNYRGPRTKDDIIEF 125
           + G     Y+G R  + + E+
Sbjct: 161 RDGKKVDQYKGKRDLESLREY 181



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 23/42 (54%), Positives = 29/42 (69%), Gaps = 1/42 (2%)

Query: 77  VKVGKMDATSYSSIASEFGVRGYPTIKLLK-GDLAYNYRGPR 117
           V V K+D T++S + S  GVRGYPT+KL K G  A  Y+GPR
Sbjct: 6   VYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPR 47


>gi|94966757 protein disulfide isomerase A2 [Homo sapiens]
          Length = 525

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 34/90 (37%), Positives = 51/90 (56%), Gaps = 3/90 (3%)

Query: 45  LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 104
           LV+FYAPWCGHC+ L P +++    + +    V + K+D  +   +A EFGV  YPT+K 
Sbjct: 63  LVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKF 122

Query: 105 LK-GDLAY--NYRGPRTKDDIIEFAHRVSG 131
            + G+  +   Y GPR  + I E+  R  G
Sbjct: 123 FRNGNRTHPEEYTGPRDAEGIAEWLRRRVG 152



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 31/95 (32%), Positives = 45/95 (47%), Gaps = 9/95 (9%)

Query: 34  SFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASE 93
           +F E +N     V FYAPWC HCK++ P W E   E       + + ++DAT+    A  
Sbjct: 402 AFDETKNV---FVKFYAPWCTHCKEMAPAW-EALAEKYQDHEDIIIAELDATANELDA-- 455

Query: 94  FGVRGYPTIKLL---KGDLAYNYRGPRTKDDIIEF 125
           F V G+PT+K      G     Y+  R  +   +F
Sbjct: 456 FAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKF 490


>gi|151101292 thioredoxin domain containing 1 [Homo sapiens]
          Length = 280

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 38/111 (34%), Positives = 56/111 (50%), Gaps = 9/111 (8%)

Query: 32  DESFKENRNDDIWLVDFYAPWCGHCKKLEPIWN---EVGLEMKSIGSPVKVGKMDATSYS 88
           DE+++E    D W+++FYAPWC  C+ L+P W    E G +++     V + K+D T   
Sbjct: 36  DENWRELLEGD-WMIEFYAPWCPACQNLQPEWESFAEWGEDLE-----VNIAKVDVTEQP 89

Query: 89  SIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPS 139
            ++  F +   PTI   K      Y+GPRTK D I F        I P+ S
Sbjct: 90  GLSGRFIITALPTIYHCKDGEFRRYQGPRTKKDFINFISDKEWKSIEPVSS 140


>gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo
           sapiens]
          Length = 793

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 26/60 (43%), Positives = 36/60 (60%), Gaps = 3/60 (5%)

Query: 44  WLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIK 103
           W++DFYAPWCG C+   P   E  L  + I   VK GK+D  +Y+    + G+R YPT+K
Sbjct: 691 WVIDFYAPWCGPCQNFAP---EFELLARMIKGKVKAGKVDCQAYAQTCQKAGIRAYPTVK 747



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 26/84 (30%), Positives = 48/84 (57%), Gaps = 5/84 (5%)

Query: 32  DESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIA 91
           +E   + +++++W+VDFY+PWC  C+ L P W  +    +++   + VG +D   Y S  
Sbjct: 567 NELVTQRKHNEVWMVDFYSPWCHPCQVLMPEWKRMA---RTLTGLINVGSIDCQQYHSFC 623

Query: 92  SEFGVRGYPTIKLL--KGDLAYNY 113
           ++  V+ YP I+    K + AY+Y
Sbjct: 624 AQENVQRYPEIRFFPPKSNKAYHY 647



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 4/86 (4%)

Query: 42  DIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPT 101
           ++W V+FY+P C HC  L P W +   E+  +   +++G ++      +    GV  YP+
Sbjct: 147 ELWFVNFYSPGCSHCHDLAPTWRDFAKEVDGL---LRIGAVNCGDDRMLCRMKGVNSYPS 203

Query: 102 IKLLKGDLA-YNYRGPRTKDDIIEFA 126
           + + +  +A   Y G R+K+ ++ FA
Sbjct: 204 LFIFRSGMAPVKYHGDRSKESLVSFA 229



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 25/82 (30%), Positives = 42/82 (51%), Gaps = 3/82 (3%)

Query: 44  WLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIK 103
           WLVDF+APWC  C+ L P   E+      +   +K G +D T +  + + + ++ YPT  
Sbjct: 471 WLVDFFAPWCPPCRALLP---ELRRASNLLYGQLKFGTLDCTVHEGLCNMYNIQAYPTTV 527

Query: 104 LLKGDLAYNYRGPRTKDDIIEF 125
           +      + Y G  + + I+EF
Sbjct: 528 VFNQSNIHEYEGHHSAEQILEF 549


>gi|5803121 protein disulfide isomerase A5 [Homo sapiens]
          Length = 519

 Score = 58.9 bits (141), Expect = 9e-09
 Identities = 37/120 (30%), Positives = 57/120 (47%), Gaps = 8/120 (6%)

Query: 29  EDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMK-SIGSPVKVGKMDATSY 87
           ED D+  KE+ +    LV F+APWCGHCKK++P + +    +     S   +  +DAT  
Sbjct: 284 EDFDQFVKEHSSV---LVMFHAPWCGHCKKMKPEFEKAAEALHGEADSSGVLAAVDATVN 340

Query: 88  SSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQ 147
            ++A  F +  +PT+K  K    Y     RTK   +E+          P P +  +E  Q
Sbjct: 341 KALAERFHISEFPTLKYFKNGEKYAVPVLRTKKKFLEWMQNPEA----PPPPEPTWEEQQ 396



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 28/84 (33%), Positives = 47/84 (55%), Gaps = 5/84 (5%)

Query: 45  LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVG-KMDATSYSSIASEFGVRGYPTIK 103
           L+ FYAPWC  CK++ P + +   +++  G  V  G  + ++ + +I  E+ VRG+PTI 
Sbjct: 174 LIMFYAPWCSMCKRMMPHFQKAATQLR--GHAVLAGMNVYSSEFENIKEEYSVRGFPTIC 231

Query: 104 LL-KGDLAYNYRG-PRTKDDIIEF 125
              KG   + Y     T +DI+E+
Sbjct: 232 YFEKGRFLFQYDNYGSTAEDIVEW 255



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 7/94 (7%)

Query: 29  EDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDAT--S 86
           ++  E+ K+ ++    LV FYAPWC HCKK+ P +       K     +    +D     
Sbjct: 405 DNFRETLKKKKHT---LVMFYAPWCPHCKKVIPHFTATADAFKD-DRKIACAAVDCVKDK 460

Query: 87  YSSIASEFGVRGYPTIKLLK-GDLAYNYRGPRTK 119
              +  +  V+GYPT      G  A  Y   RT+
Sbjct: 461 NQDLCQQEAVKGYPTFHYYHYGKFAEKYDSDRTE 494


>gi|145580631 quiescin Q6 sulfhydryl oxidase 2 [Homo sapiens]
          Length = 698

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 7/80 (8%)

Query: 44  WLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDA--TSYSSIASEFGVRGYPT 101
           WLV FY+ WCGHC    P W  +  +++   S ++V  +D       ++  ++ +  YPT
Sbjct: 82  WLVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPT 141

Query: 102 IKLLKG-----DLAYNYRGP 116
            +  K          N++GP
Sbjct: 142 FRYFKAFTKEFTTGENFKGP 161


>gi|52487191 thioredoxin domain containing 4 (endoplasmic reticulum)
           [Homo sapiens]
          Length = 406

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 8/102 (7%)

Query: 29  EDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKS---IGSPVKVGKMDAT 85
           E++DE      N D+ LV+FYA WC   + L PI+ E    +K      + V   ++D  
Sbjct: 37  ENIDEILN---NADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCD 93

Query: 86  SYSSIASEFGVRGYPTIKLLKGDLAY--NYRGPRTKDDIIEF 125
            +S IA  + +  YPT+KL +  +     YRG R+   + ++
Sbjct: 94  QHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADY 135


>gi|51873067 quiescin Q6 sulfhydryl oxidase 1 isoform b [Homo
           sapiens]
          Length = 604

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 19/65 (29%), Positives = 36/65 (55%), Gaps = 2/65 (3%)

Query: 44  WLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDAT--SYSSIASEFGVRGYPT 101
           W V+F+A WCGHC    P W  +  ++K+    + +  +D    + S++  +F + G+PT
Sbjct: 61  WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT 120

Query: 102 IKLLK 106
           ++  K
Sbjct: 121 VRFFK 125


>gi|13325075 quiescin Q6 sulfhydryl oxidase 1 isoform a [Homo
           sapiens]
          Length = 747

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 19/65 (29%), Positives = 36/65 (55%), Gaps = 2/65 (3%)

Query: 44  WLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDAT--SYSSIASEFGVRGYPT 101
           W V+F+A WCGHC    P W  +  ++K+    + +  +D    + S++  +F + G+PT
Sbjct: 61  WAVEFFASWCGHCIAFAPTWKALAEDVKAWRPALYLAALDCAEETNSAVCRDFNIPGFPT 120

Query: 102 IKLLK 106
           ++  K
Sbjct: 121 VRFFK 125


>gi|227430327 calsequestrin 1 [Homo sapiens]
          Length = 396

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 58/299 (19%), Positives = 125/299 (41%), Gaps = 22/299 (7%)

Query: 68  LEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAH 127
           LE K +G     G +D+   +++A + G+    ++ + KGD    Y G  + D I+EF  
Sbjct: 99  LEDKGVG----FGLVDSEKDAAVAKKLGLTEVDSMYVFKGDEVIEYDGEFSADTIVEFLL 154

Query: 128 RV---SGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYFFSAS 184
            V      LI      Q FE+++   ++   +   +S   + + DAA E   Y  FF+  
Sbjct: 155 DVLEDPVELIEGERELQAFENIEDEIKLIGYFKSKDSEHYKAFEDAAEEFHPYIPFFATF 214

Query: 185 EEVVPEYVTLK--EMPAVLVFKDETYFVYDE-YEDGDLSSWINRERFQNYLAMDGFLLYE 241
           +  V + +TLK  E+     F +E   + D+   + ++ +++   R      +    +YE
Sbjct: 215 DSKVAKKLTLKLNEIDFYEAFMEEPVTIPDKPNSEEEIVNFVEEHRRSTLRKLKPESMYE 274

Query: 242 LGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGND------Y 295
             +        V   +    +       ++ VA+D  +  + D     +D +D      Y
Sbjct: 275 TWEDDMDGIHIVAFAEEADPDGFEFLETLKAVAQDNTE--NPDLSIIWIDPDDFPLLVPY 332

Query: 296 INTLLMDELTVPTVVVLNTSNQQYFLL----DRQIKNVEDMVQFINNILDGTVEAQGGD 350
                  +L+ P + V+N ++     +    +  + + E++  ++ ++L+G +  +  D
Sbjct: 333 WEKTFDIDLSAPQIGVVNVTDADSVWMEMDDEEDLPSAEELEDWLEDVLEGEINTEDDD 391


>gi|40254947 thioredoxin-related transmembrane protein 4 [Homo
           sapiens]
          Length = 349

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 2/94 (2%)

Query: 44  WLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIK 103
           W++ FYAPWC  C++ +  W       + +   + VGK+D      ++  F V   P   
Sbjct: 55  WMLKFYAPWCPSCQQTDSEWEAFAKNGEIL--QISVGKVDVIQEPGLSGRFFVTTLPAFF 112

Query: 104 LLKGDLAYNYRGPRTKDDIIEFAHRVSGALIRPL 137
             K  +   YRGP   +D+  +        + PL
Sbjct: 113 HAKDGIFRRYRGPGIFEDLQNYILEKKWQSVEPL 146


>gi|21361403 thioredoxin 2 precursor [Homo sapiens]
          Length = 166

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 4/88 (4%)

Query: 45  LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 104
           +VDF+A WCG CK L P   ++  +       V + K+D   ++ +A E+ V   PT+  
Sbjct: 82  VVDFHAQWCGPCKILGPRLEKMVAKQH---GKVVMAKVDIDDHTDLAIEYEVSAVPTVLA 138

Query: 105 LK-GDLAYNYRGPRTKDDIIEFAHRVSG 131
           +K GD+   + G + +D +  F  ++ G
Sbjct: 139 MKNGDVVDKFVGIKDEDQLEAFLKKLIG 166


>gi|119395727 cardiac calsequestrin 2 precursor [Homo sapiens]
          Length = 399

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 58/299 (19%), Positives = 125/299 (41%), Gaps = 22/299 (7%)

Query: 68  LEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAH 127
           LE K+IG  +    +DA   + +A + G     ++ +LKGD    + G    D ++EF  
Sbjct: 84  LEHKAIGFVM----VDAKKEAKLAKKLGFDEEGSLYILKGDRTIEFDGEFAADVLVEFLL 139

Query: 128 RVSGALIRPLPSQ---QMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYFFSAS 184
            +    +  + S+   Q FE ++   ++   +   +S   + + +AA     Y  FF+  
Sbjct: 140 DLIEDPVEIISSKLEVQAFERIEDYIKLIGFFKSEDSEYYKAFEEAAEHFQPYIKFFATF 199

Query: 185 EEVVPEYVTLK--EMPAVLVFKDETYFVYDE-YEDGDLSSWINRERFQNYLAMDGFLLYE 241
           ++ V + ++LK  E+     F DE   + ++ Y + +L  ++   +      +    ++E
Sbjct: 200 DKGVAKKLSLKMNEVDFYEPFMDEPIAIPNKPYTEEELVEFVKEHQRPTLRRLRPEEMFE 259

Query: 242 LGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGND------Y 295
             +        V   + +  +      I+++VARD  D  + D     +D +D      Y
Sbjct: 260 TWEDDLNGIHIVAFAEKSDPDGYEFLEILKQVARDNTD--NPDLSILWIDPDDFPLLVAY 317

Query: 296 INTLLMDELTVPTVVVLNTSNQQYFLL----DRQIKNVEDMVQFINNILDGTVEAQGGD 350
                  +L  P + V+N ++     +    D  +   E++  +I ++L G +  +  D
Sbjct: 318 WEKTFKIDLFRPQIGVVNVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDD 376


>gi|221136993 thioredoxin domain containing 14 isoform 2 [Homo
           sapiens]
          Length = 258

 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 20/75 (26%), Positives = 39/75 (52%), Gaps = 3/75 (4%)

Query: 31  LDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSI 90
           +DE  + ++    W+V+F+A W   C+   PI+ ++ L+    G  +  GK+D   Y+ +
Sbjct: 108 IDEELERDKRVT-WIVEFFANWSNDCQSFAPIYADLSLKYNCTG--LNFGKVDVGRYTDV 164

Query: 91  ASEFGVRGYPTIKLL 105
           ++ + V   P  K L
Sbjct: 165 STRYKVSTSPLTKQL 179


>gi|7705726 thioredoxin domain containing 14 isoform 1 [Homo
           sapiens]
          Length = 296

 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 20/75 (26%), Positives = 39/75 (52%), Gaps = 3/75 (4%)

Query: 31  LDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSI 90
           +DE  + ++    W+V+F+A W   C+   PI+ ++ L+    G  +  GK+D   Y+ +
Sbjct: 146 IDEELERDKRVT-WIVEFFANWSNDCQSFAPIYADLSLKYNCTG--LNFGKVDVGRYTDV 202

Query: 91  ASEFGVRGYPTIKLL 105
           ++ + V   P  K L
Sbjct: 203 STRYKVSTSPLTKQL 217


>gi|56687498 DnaJ (Hsp40) homolog, subfamily C, member 16 [Homo
           sapiens]
          Length = 782

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 40/188 (21%), Positives = 83/188 (44%), Gaps = 19/188 (10%)

Query: 29  EDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYS 88
           E + +SFK+      +L+   + WC  C  +EP+W EV  E++ +G  V +G + A    
Sbjct: 152 EVVPDSFKKP-----YLIKITSDWCFSCIHIEPVWKEVIQELEELG--VGIGVVHAGYER 204

Query: 89  SIASEFGVRGYPTI-KLLKGDLAYNYRGPRTKDDIIEFAHR-VSGALIRPLPSQQM---- 142
            +A   G    P+I  ++ G +++ +     ++++ +F    + G L+  + ++      
Sbjct: 205 RLAHHLGAHSTPSILGIINGKISF-FHNAVVRENLRQFVESLLPGNLVEKVTNKNYVRFL 263

Query: 143 --FEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYFF---SASEEVVPEYVTLKEM 197
             ++   K H + F        L +    A  + + + Y +     +EE+   Y      
Sbjct: 264 SGWQQENKPHVLLFDQTPIVPLLYKLTAFAYKDYLSFGYVYVGLRGTEEMTRRYNINIYA 323

Query: 198 PAVLVFKD 205
           P +LVFK+
Sbjct: 324 PTLLVFKE 331


>gi|94421469 disulfide isomerase [Homo sapiens]
          Length = 360

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 36/152 (23%), Positives = 58/152 (38%), Gaps = 20/152 (13%)

Query: 35  FKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEF 94
           F      D  LV FY PWC     L P +N +     ++        +DA+ +SS+++ F
Sbjct: 202 FLNPNGSDCTLVLFYTPWCRFSASLAPHFNSLPRAFPAL----HFLALDASQHSSLSTRF 257

Query: 95  GVRGYPTIKLLKG--DLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFEHMQKRHRV 152
           G    P I L +G   +A      RT + +  F    +G              ++ +  V
Sbjct: 258 GTVAVPNILLFQGAKPMARFNHTDRTLETLKIFIFNQTG--------------IEAKKNV 303

Query: 153 FFVYVGGESPLKEKYIDAASELIVYTYFFSAS 184
                    PL    I +   L+V++ FF  S
Sbjct: 304 VVTQADQIGPLPSTLIKSVDWLLVFSLFFLIS 335


>gi|50592994 thioredoxin [Homo sapiens]
          Length = 105

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 9/80 (11%)

Query: 27  FVEDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATS 86
           F E LD +      D + +VDF A WCG CK ++P ++ +  +     S V   ++D   
Sbjct: 11  FQEALDAA-----GDKLVVVDFSATWCGPCKMIKPFFHSLSEKY----SNVIFLEVDVDD 61

Query: 87  YSSIASEFGVRGYPTIKLLK 106
              +ASE  V+  PT +  K
Sbjct: 62  CQDVASECEVKCMPTFQFFK 81


>gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo
           sapiens]
          Length = 486

 Score = 37.7 bits (86), Expect = 0.022
 Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 5/78 (6%)

Query: 29  EDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYS 88
           ED + S KE   + +  VDF A WCG C+ + P ++ + ++ +     V   ++DA +  
Sbjct: 390 EDFEASLKE-AGERLVAVDFSATWCGPCRTIRPFFHALSVKHED----VVFLEVDADNCE 444

Query: 89  SIASEFGVRGYPTIKLLK 106
            +  E  +   PT +  K
Sbjct: 445 EVVRECAIMCVPTFQFYK 462


>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo
           sapiens]
          Length = 553

 Score = 37.7 bits (86), Expect = 0.022
 Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 5/78 (6%)

Query: 29  EDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYS 88
           ED + S KE   + +  VDF A WCG C+ + P ++ + ++ +     V   ++DA +  
Sbjct: 457 EDFEASLKE-AGERLVAVDFSATWCGPCRTIRPFFHALSVKHED----VVFLEVDADNCE 511

Query: 89  SIASEFGVRGYPTIKLLK 106
            +  E  +   PT +  K
Sbjct: 512 EVVRECAIMCVPTFQFYK 529


>gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo
           sapiens]
          Length = 486

 Score = 37.7 bits (86), Expect = 0.022
 Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 5/78 (6%)

Query: 29  EDLDESFKENRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYS 88
           ED + S KE   + +  VDF A WCG C+ + P ++ + ++ +     V   ++DA +  
Sbjct: 390 EDFEASLKE-AGERLVAVDFSATWCGPCRTIRPFFHALSVKHED----VVFLEVDADNCE 444

Query: 89  SIASEFGVRGYPTIKLLK 106
            +  E  +   PT +  K
Sbjct: 445 EVVRECAIMCVPTFQFYK 462


>gi|28372543 protein disulfide isomerase-like, testis expressed
           [Homo sapiens]
          Length = 584

 Score = 33.9 bits (76), Expect = 0.31
 Identities = 16/49 (32%), Positives = 31/49 (63%), Gaps = 2/49 (4%)

Query: 38  NRNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATS 86
           ++  D++++ FYAPW   CK L P+  E+G + ++  S + + K+D T+
Sbjct: 403 DKEKDVFVM-FYAPWSKKCKMLFPLLEELGRKYQN-HSTIIIAKIDVTA 449


>gi|148839372 thioredoxin domain containing 3 [Homo sapiens]
          Length = 588

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 9/32 (28%), Positives = 21/32 (65%)

Query: 39 RNDDIWLVDFYAPWCGHCKKLEPIWNEVGLEM 70
          +N  + ++D Y  WCG C+ ++P++ ++  E+
Sbjct: 25 QNKGLTVIDVYQAWCGPCRAMQPLFRKLKNEL 56


>gi|54633317 thioredoxin domain containing 11 [Homo sapiens]
          Length = 958

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 6/72 (8%)

Query: 45  LVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKL 104
           L+ +YAPWCG C  L  I+ ++   +        V ++D  S + +  EF V   PT+  
Sbjct: 684 LLLYYAPWCGFCPSLNHIFIQLARNLPM--DTFTVARID-VSQNDLPWEFMVDRLPTVLF 740

Query: 105 L---KGDLAYNY 113
               + DL+  Y
Sbjct: 741 FPCNRKDLSVKY 752



 Score = 29.3 bits (64), Expect = 7.7
 Identities = 12/28 (42%), Positives = 17/28 (60%)

Query: 27  FVEDLDESFKENRNDDIWLVDFYAPWCG 54
           F   LD +    R+ ++ L+ FYAPWCG
Sbjct: 111 FQGQLDYAEYVRRDSEVVLLFFYAPWCG 138


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,735,010
Number of Sequences: 37866
Number of extensions: 731217
Number of successful extensions: 2684
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2606
Number of HSP's gapped (non-prelim): 67
length of query: 454
length of database: 18,247,518
effective HSP length: 106
effective length of query: 348
effective length of database: 14,233,722
effective search space: 4953335256
effective search space used: 4953335256
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.