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Search of human proteins with 38505194
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38505194 prostaglandin E receptor 1, subtype EP1 [Homo
sapiens]
(402 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38505194 prostaglandin E receptor 1, subtype EP1 [Homo sapiens] 795 0.0
gi|4506261 prostaglandin F receptor isoform a precursor [Homo sa... 224 1e-58
gi|4507381 thromboxane A2 receptor [Homo sapiens] 194 2e-49
gi|88758606 prostaglandin F receptor isoform b precursor [Homo s... 174 2e-43
gi|38505176 prostaglandin E receptor 3, subtype EP3 isoform 3 [H... 163 2e-40
gi|38505180 prostaglandin E receptor 3, subtype EP3 isoform 5 [H... 163 3e-40
gi|38505172 prostaglandin E receptor 3, subtype EP3 isoform 1 [H... 163 3e-40
gi|89276764 prostaglandin E receptor 3, subtype EP3 isoform 2 [H... 162 4e-40
gi|38505188 prostaglandin E receptor 3, subtype EP3 isoform 4 [H... 162 4e-40
gi|38505186 prostaglandin E receptor 3, subtype EP3 isoform 8 [H... 162 4e-40
gi|38505182 prostaglandin E receptor 3, subtype EP3 isoform 6 [H... 162 4e-40
gi|38505178 prostaglandin E receptor 3, subtype EP3 isoform 4 [H... 162 4e-40
gi|186659506 prostaglandin E receptor 3, subtype EP3 isoform 4 [... 162 4e-40
gi|38505184 prostaglandin E receptor 3, subtype EP3 isoform 7 [H... 162 7e-40
gi|4506259 prostaglandin E receptor 4, subtype EP4 [Homo sapiens] 130 2e-30
gi|31881630 prostaglandin E receptor 2 (subtype EP2), 53kDa [Hom... 127 1e-29
gi|4506263 prostaglandin I2 (prostacyclin) receptor (IP) [Homo s... 114 2e-25
gi|28466969 prostaglandin D2 receptor [Homo sapiens] 92 8e-19
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens] 59 8e-09
gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens] 52 9e-07
gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens] 52 9e-07
gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens] 52 9e-07
gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens] 52 9e-07
gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens] 52 9e-07
gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens] 52 9e-07
gi|23592220 G protein-coupled receptor 26 [Homo sapiens] 50 3e-06
gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens] 47 3e-05
gi|4557265 beta-1-adrenergic receptor [Homo sapiens] 44 2e-04
gi|13540517 endothelial differentiation, sphingolipid G-protein-... 44 2e-04
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] 44 3e-04
>gi|38505194 prostaglandin E receptor 1, subtype EP1 [Homo sapiens]
Length = 402
Score = 795 bits (2053), Expect = 0.0
Identities = 402/402 (100%), Positives = 402/402 (100%)
Query: 1 MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQA 60
MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQA
Sbjct: 1 MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQA 60
Query: 61 AGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFF 120
AGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFF
Sbjct: 61 AGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFF 120
Query: 121 GLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYE 180
GLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYE
Sbjct: 121 GLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYE 180
Query: 181 LQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRR 240
LQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRR
Sbjct: 181 LQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRR 240
Query: 241 PPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLV 300
PPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLV
Sbjct: 241 PPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLV 300
Query: 301 GIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLR 360
GIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLR
Sbjct: 301 GIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLR 360
Query: 361 QLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF 402
QLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
Sbjct: 361 QLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF 402
>gi|4506261 prostaglandin F receptor isoform a precursor [Homo
sapiens]
Length = 359
Score = 224 bits (571), Expect = 1e-58
Identities = 135/394 (34%), Positives = 207/394 (52%), Gaps = 59/394 (14%)
Query: 7 LNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQAAGRLRR 66
++++ + + + AA + NT+ + S + MT+G +SN LA+A+L +A R R+
Sbjct: 1 MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQ 60
Query: 67 RRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRA-----PAGGACHFLGGCMVFFG 121
+ S A+FLL + L+ TD GH+I GA+ + +Y + + + C G CMVF G
Sbjct: 61 K-SKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSG 119
Query: 122 LCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYEL 181
LCPLLLG MA+ERC+GVT+P+ H+ +++ ++ L+ V A+ +ALLP+ Y++
Sbjct: 120 LCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKI 179
Query: 182 QYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRP 241
Q TWCF W LF+ LGL+AL +L+CN ++G+ LLR +++
Sbjct: 180 QASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFK------ 233
Query: 242 PPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVG 301
S R+ R+H +EMV QL+
Sbjct: 234 ----------------------------------------SQQHRQGRSHHLEMVIQLLA 253
Query: 302 IMVVSCICWSPMLVLVA-LAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLR 360
IM VSCICWSP LV +A + + G S A+R+A+WNQILDPWVYILLR+AVL+
Sbjct: 254 IMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILDPWVYILLRKAVLK 313
Query: 361 QLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSS 394
L +L G ++ WE SS+++S
Sbjct: 314 NLYKLASQCCGVH------VISLHIWELSSIKNS 341
>gi|4507381 thromboxane A2 receptor [Homo sapiens]
Length = 343
Score = 194 bits (492), Expect = 2e-49
Identities = 141/407 (34%), Positives = 195/407 (47%), Gaps = 86/407 (21%)
Query: 1 MSPC-GPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQ 59
+ PC P N++L E A+PW + V +G SNLLAL++LA
Sbjct: 8 LGPCFRPTNITLE-ERRLIASPWFAASFCV---------------VGLASNLLALSVLAG 51
Query: 60 AAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTA-----GRAPAGGACHFLG 114
A R + ++FL F+ L+ TD G ++ G +V+ + A P C F+G
Sbjct: 52 A--RQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMG 109
Query: 115 GCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLA 174
M+FFGL PLLLG MA ER +G+TRP A S RA + V A ALA+ LLPL
Sbjct: 110 VVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLL 169
Query: 175 RVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARW 234
VGRY +QYPG+WCF+ LG G LF+ LG +++ + + NT+S L
Sbjct: 170 GVGRYTVQYPGSWCFLTLGAESG--DVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHV-- 225
Query: 235 RRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVE 294
HG +A +R R +VE
Sbjct: 226 --------------------YHGQEAAQ-----------------------QRPRDSEVE 242
Query: 295 MVGQLVGIMVVSCICWSPMLVLVALAV---------GGWSSTSLQRPLFLAVRLASWNQI 345
M+ QL+GIMVV+ +CW P+LV +A V G S + ++ L + +R+A+WNQI
Sbjct: 243 MMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQI 302
Query: 346 LDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLR 392
LDPWVYIL R+AVLR+L L R P L L P + S L+
Sbjct: 303 LDPWVYILFRRAVLRRLQPRLSTR------PRSLSLQPQLTQRSGLQ 343
>gi|88758606 prostaglandin F receptor isoform b precursor [Homo
sapiens]
Length = 297
Score = 174 bits (440), Expect = 2e-43
Identities = 103/313 (32%), Positives = 161/313 (51%), Gaps = 52/313 (16%)
Query: 7 LNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQAAGRLRR 66
++++ + + + AA + NT+ + S + MT+G +SN LA+A+L +A R R+
Sbjct: 1 MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQ 60
Query: 67 RRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRA-----PAGGACHFLGGCMVFFG 121
+ S A+FLL + L+ TD GH+I GA+ + +Y + + + C G CMVF G
Sbjct: 61 K-SKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSG 119
Query: 122 LCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYEL 181
LCPLLLG MA+ERC+GVT+P+ H+ +++ ++ L+ V A+ +ALLP+ Y++
Sbjct: 120 LCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKI 179
Query: 182 QYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRP 241
Q TWCF W LF+ LGL+AL +L+CN ++G+ LLR +++
Sbjct: 180 QASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFK------ 233
Query: 242 PPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVG 301
S R+ R+H +EMV QL+
Sbjct: 234 ----------------------------------------SQQHRQGRSHHLEMVIQLLA 253
Query: 302 IMVVSCICWSPML 314
IM VSCICWSP L
Sbjct: 254 IMCVSCICWSPFL 266
>gi|38505176 prostaglandin E receptor 3, subtype EP3 isoform 3 [Homo
sapiens]
Length = 393
Score = 163 bits (413), Expect = 2e-40
Identities = 128/400 (32%), Positives = 177/400 (44%), Gaps = 85/400 (21%)
Query: 4 CGPLNLSLAGEATTCAAPWVPNTSAV--------PPSG-----ASPALPIFSMTLGAVSN 50
C LN S G W P SA P SG S A PI + G V N
Sbjct: 14 CTRLNHSYTGM-------WAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGN 66
Query: 51 LLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRA-----P 105
LA+ L++++ R +R + FLL + L TDL G ++ +V+ +Y + + P
Sbjct: 67 ALAMLLVSRSYRRRESKRKKS-FLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDP 125
Query: 106 AGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVA 165
+G C F G M FGL L + MAVER + + P +A+ + R L V
Sbjct: 126 SGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAV 185
Query: 166 LAVALLPLARVGRYELQYPGTWCFIGLGPPG-------GWRQALLAGLFASLGLVALLAA 218
LA ALLP+ VG+Y +Q+PGTWCFI G G W A FA LGL+AL
Sbjct: 186 LAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVT 245
Query: 219 LVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGG 278
CN + AL+ SR A+ S +WG +A
Sbjct: 246 FSCNLATIKALV-------SRCRAKATASQSSAQWGRITTETAI---------------- 282
Query: 279 SRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSS-------TSLQR 331
QL+GIM V +CWSP+L+++ + +S T Q+
Sbjct: 283 -------------------QLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQK 323
Query: 332 P---LFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPP 368
+AVRLAS NQILDPWVY+LLR+ +LR+ + + P
Sbjct: 324 ECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQEMGP 363
>gi|38505180 prostaglandin E receptor 3, subtype EP3 isoform 5 [Homo
sapiens]
Length = 388
Score = 163 bits (412), Expect = 3e-40
Identities = 132/416 (31%), Positives = 181/416 (43%), Gaps = 90/416 (21%)
Query: 4 CGPLNLSLAGEATTCAAPWVPNTSAV--------PPSG-----ASPALPIFSMTLGAVSN 50
C LN S G W P SA P SG S A PI + G V N
Sbjct: 14 CTRLNHSYTGM-------WAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGN 66
Query: 51 LLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRA-----P 105
LA+ L++++ R +R + FLL + L TDL G ++ +V+ +Y + + P
Sbjct: 67 ALAMLLVSRSYRRRESKRKKS-FLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDP 125
Query: 106 AGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVA 165
+G C F G M FGL L + MAVER + + P +A+ + R L V
Sbjct: 126 SGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAV 185
Query: 166 LAVALLPLARVGRYELQYPGTWCFIGLGPPG-------GWRQALLAGLFASLGLVALLAA 218
LA ALLP+ VG+Y +Q+PGTWCFI G G W A FA LGL+AL
Sbjct: 186 LAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVT 245
Query: 219 LVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGG 278
CN + AL+ SR A+ S +WG +A
Sbjct: 246 FSCNLATIKALV-------SRCRAKATASQSSAQWGRITTETAI---------------- 282
Query: 279 SRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSS-------TSLQR 331
QL+GIM V +CWSP+L+++ + +S T Q+
Sbjct: 283 -------------------QLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQK 323
Query: 332 P---LFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLP-----PRAGAKGGPAGL 379
+AVRLAS NQILDPWVY+LLR+ +LR+ ++ G KG P L
Sbjct: 324 ECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQVANAVSSCSNDGQKGQPISL 379
>gi|38505172 prostaglandin E receptor 3, subtype EP3 isoform 1 [Homo
sapiens]
Length = 425
Score = 163 bits (412), Expect = 3e-40
Identities = 133/426 (31%), Positives = 185/426 (43%), Gaps = 87/426 (20%)
Query: 4 CGPLNLSLAGEATTCAAPWVPNTSAV--------PPSG-----ASPALPIFSMTLGAVSN 50
C LN S G W P SA P SG S A PI + G V N
Sbjct: 14 CTRLNHSYTGM-------WAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGN 66
Query: 51 LLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRA-----P 105
LA+ L++++ R +R + FLL + L TDL G ++ +V+ +Y + + P
Sbjct: 67 ALAMLLVSRSYRRRESKRKKS-FLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDP 125
Query: 106 AGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVA 165
+G C F G M FGL L + MAVER + + P +A+ + R L V
Sbjct: 126 SGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAV 185
Query: 166 LAVALLPLARVGRYELQYPGTWCFIGLGPPG-------GWRQALLAGLFASLGLVALLAA 218
LA ALLP+ VG+Y +Q+PGTWCFI G G W A FA LGL+AL
Sbjct: 186 LAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVT 245
Query: 219 LVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGG 278
CN + AL+ SR A+ S +WG +A
Sbjct: 246 FSCNLATIKALV-------SRCRAKATASQSSAQWGRITTETAI---------------- 282
Query: 279 SRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSS-------TSLQR 331
QL+GIM V +CWSP+L+++ + +S T Q+
Sbjct: 283 -------------------QLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQK 323
Query: 332 P---LFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGG--PAGLGLTPSAW 386
+AVRLAS NQILDPWVY+LLR+ +LR+ ++ R + P + PS +
Sbjct: 324 ECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQMRKRRLREQAPLLPTSTVIDPSRF 383
Query: 387 EASSLR 392
A R
Sbjct: 384 CAQPFR 389
>gi|89276764 prostaglandin E receptor 3, subtype EP3 isoform 2 [Homo
sapiens]
Length = 402
Score = 162 bits (411), Expect = 4e-40
Identities = 127/397 (31%), Positives = 176/397 (44%), Gaps = 85/397 (21%)
Query: 4 CGPLNLSLAGEATTCAAPWVPNTSAV--------PPSG-----ASPALPIFSMTLGAVSN 50
C LN S G W P SA P SG S A PI + G V N
Sbjct: 14 CTRLNHSYTGM-------WAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGN 66
Query: 51 LLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRA-----P 105
LA+ L++++ R +R + FLL + L TDL G ++ +V+ +Y + + P
Sbjct: 67 ALAMLLVSRSYRRRESKRKKS-FLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDP 125
Query: 106 AGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVA 165
+G C F G M FGL L + MAVER + + P +A+ + R L V
Sbjct: 126 SGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAV 185
Query: 166 LAVALLPLARVGRYELQYPGTWCFIGLGPPG-------GWRQALLAGLFASLGLVALLAA 218
LA ALLP+ VG+Y +Q+PGTWCFI G G W A FA LGL+AL
Sbjct: 186 LAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVT 245
Query: 219 LVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGG 278
CN + AL+ SR A+ S +WG +A
Sbjct: 246 FSCNLATIKALV-------SRCRAKATASQSSAQWGRITTETAI---------------- 282
Query: 279 SRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSS-------TSLQR 331
QL+GIM V +CWSP+L+++ + +S T Q+
Sbjct: 283 -------------------QLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQK 323
Query: 332 P---LFLAVRLASWNQILDPWVYILLRQAVLRQLLRL 365
+AVRLAS NQILDPWVY+LLR+ +LR+ ++
Sbjct: 324 ECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM 360
>gi|38505188 prostaglandin E receptor 3, subtype EP3 isoform 4 [Homo
sapiens]
Length = 390
Score = 162 bits (411), Expect = 4e-40
Identities = 127/397 (31%), Positives = 176/397 (44%), Gaps = 85/397 (21%)
Query: 4 CGPLNLSLAGEATTCAAPWVPNTSAV--------PPSG-----ASPALPIFSMTLGAVSN 50
C LN S G W P SA P SG S A PI + G V N
Sbjct: 14 CTRLNHSYTGM-------WAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGN 66
Query: 51 LLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRA-----P 105
LA+ L++++ R +R + FLL + L TDL G ++ +V+ +Y + + P
Sbjct: 67 ALAMLLVSRSYRRRESKRKKS-FLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDP 125
Query: 106 AGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVA 165
+G C F G M FGL L + MAVER + + P +A+ + R L V
Sbjct: 126 SGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAV 185
Query: 166 LAVALLPLARVGRYELQYPGTWCFIGLGPPG-------GWRQALLAGLFASLGLVALLAA 218
LA ALLP+ VG+Y +Q+PGTWCFI G G W A FA LGL+AL
Sbjct: 186 LAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVT 245
Query: 219 LVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGG 278
CN + AL+ SR A+ S +WG +A
Sbjct: 246 FSCNLATIKALV-------SRCRAKATASQSSAQWGRITTETAI---------------- 282
Query: 279 SRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSS-------TSLQR 331
QL+GIM V +CWSP+L+++ + +S T Q+
Sbjct: 283 -------------------QLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQK 323
Query: 332 P---LFLAVRLASWNQILDPWVYILLRQAVLRQLLRL 365
+AVRLAS NQILDPWVY+LLR+ +LR+ ++
Sbjct: 324 ECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI 360
>gi|38505186 prostaglandin E receptor 3, subtype EP3 isoform 8 [Homo
sapiens]
Length = 418
Score = 162 bits (411), Expect = 4e-40
Identities = 127/397 (31%), Positives = 176/397 (44%), Gaps = 85/397 (21%)
Query: 4 CGPLNLSLAGEATTCAAPWVPNTSAV--------PPSG-----ASPALPIFSMTLGAVSN 50
C LN S G W P SA P SG S A PI + G V N
Sbjct: 14 CTRLNHSYTGM-------WAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGN 66
Query: 51 LLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRA-----P 105
LA+ L++++ R +R + FLL + L TDL G ++ +V+ +Y + + P
Sbjct: 67 ALAMLLVSRSYRRRESKRKKS-FLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDP 125
Query: 106 AGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVA 165
+G C F G M FGL L + MAVER + + P +A+ + R L V
Sbjct: 126 SGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAV 185
Query: 166 LAVALLPLARVGRYELQYPGTWCFIGLGPPG-------GWRQALLAGLFASLGLVALLAA 218
LA ALLP+ VG+Y +Q+PGTWCFI G G W A FA LGL+AL
Sbjct: 186 LAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVT 245
Query: 219 LVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGG 278
CN + AL+ SR A+ S +WG +A
Sbjct: 246 FSCNLATIKALV-------SRCRAKATASQSSAQWGRITTETAI---------------- 282
Query: 279 SRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSS-------TSLQR 331
QL+GIM V +CWSP+L+++ + +S T Q+
Sbjct: 283 -------------------QLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQK 323
Query: 332 P---LFLAVRLASWNQILDPWVYILLRQAVLRQLLRL 365
+AVRLAS NQILDPWVY+LLR+ +LR+ ++
Sbjct: 324 ECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM 360
>gi|38505182 prostaglandin E receptor 3, subtype EP3 isoform 6 [Homo
sapiens]
Length = 374
Score = 162 bits (411), Expect = 4e-40
Identities = 127/397 (31%), Positives = 176/397 (44%), Gaps = 85/397 (21%)
Query: 4 CGPLNLSLAGEATTCAAPWVPNTSAV--------PPSG-----ASPALPIFSMTLGAVSN 50
C LN S G W P SA P SG S A PI + G V N
Sbjct: 14 CTRLNHSYTGM-------WAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGN 66
Query: 51 LLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRA-----P 105
LA+ L++++ R +R + FLL + L TDL G ++ +V+ +Y + + P
Sbjct: 67 ALAMLLVSRSYRRRESKRKKS-FLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDP 125
Query: 106 AGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVA 165
+G C F G M FGL L + MAVER + + P +A+ + R L V
Sbjct: 126 SGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAV 185
Query: 166 LAVALLPLARVGRYELQYPGTWCFIGLGPPG-------GWRQALLAGLFASLGLVALLAA 218
LA ALLP+ VG+Y +Q+PGTWCFI G G W A FA LGL+AL
Sbjct: 186 LAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVT 245
Query: 219 LVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGG 278
CN + AL+ SR A+ S +WG +A
Sbjct: 246 FSCNLATIKALV-------SRCRAKATASQSSAQWGRITTETAI---------------- 282
Query: 279 SRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSS-------TSLQR 331
QL+GIM V +CWSP+L+++ + +S T Q+
Sbjct: 283 -------------------QLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQK 323
Query: 332 P---LFLAVRLASWNQILDPWVYILLRQAVLRQLLRL 365
+AVRLAS NQILDPWVY+LLR+ +LR+ ++
Sbjct: 324 ECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQM 360
>gi|38505178 prostaglandin E receptor 3, subtype EP3 isoform 4 [Homo
sapiens]
Length = 390
Score = 162 bits (411), Expect = 4e-40
Identities = 127/397 (31%), Positives = 176/397 (44%), Gaps = 85/397 (21%)
Query: 4 CGPLNLSLAGEATTCAAPWVPNTSAV--------PPSG-----ASPALPIFSMTLGAVSN 50
C LN S G W P SA P SG S A PI + G V N
Sbjct: 14 CTRLNHSYTGM-------WAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGN 66
Query: 51 LLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRA-----P 105
LA+ L++++ R +R + FLL + L TDL G ++ +V+ +Y + + P
Sbjct: 67 ALAMLLVSRSYRRRESKRKKS-FLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDP 125
Query: 106 AGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVA 165
+G C F G M FGL L + MAVER + + P +A+ + R L V
Sbjct: 126 SGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAV 185
Query: 166 LAVALLPLARVGRYELQYPGTWCFIGLGPPG-------GWRQALLAGLFASLGLVALLAA 218
LA ALLP+ VG+Y +Q+PGTWCFI G G W A FA LGL+AL
Sbjct: 186 LAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVT 245
Query: 219 LVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGG 278
CN + AL+ SR A+ S +WG +A
Sbjct: 246 FSCNLATIKALV-------SRCRAKATASQSSAQWGRITTETAI---------------- 282
Query: 279 SRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSS-------TSLQR 331
QL+GIM V +CWSP+L+++ + +S T Q+
Sbjct: 283 -------------------QLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQK 323
Query: 332 P---LFLAVRLASWNQILDPWVYILLRQAVLRQLLRL 365
+AVRLAS NQILDPWVY+LLR+ +LR+ ++
Sbjct: 324 ECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI 360
>gi|186659506 prostaglandin E receptor 3, subtype EP3 isoform 4
[Homo sapiens]
Length = 390
Score = 162 bits (411), Expect = 4e-40
Identities = 127/397 (31%), Positives = 176/397 (44%), Gaps = 85/397 (21%)
Query: 4 CGPLNLSLAGEATTCAAPWVPNTSAV--------PPSG-----ASPALPIFSMTLGAVSN 50
C LN S G W P SA P SG S A PI + G V N
Sbjct: 14 CTRLNHSYTGM-------WAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGN 66
Query: 51 LLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRA-----P 105
LA+ L++++ R +R + FLL + L TDL G ++ +V+ +Y + + P
Sbjct: 67 ALAMLLVSRSYRRRESKRKKS-FLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDP 125
Query: 106 AGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVA 165
+G C F G M FGL L + MAVER + + P +A+ + R L V
Sbjct: 126 SGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAV 185
Query: 166 LAVALLPLARVGRYELQYPGTWCFIGLGPPG-------GWRQALLAGLFASLGLVALLAA 218
LA ALLP+ VG+Y +Q+PGTWCFI G G W A FA LGL+AL
Sbjct: 186 LAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVT 245
Query: 219 LVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGG 278
CN + AL+ SR A+ S +WG +A
Sbjct: 246 FSCNLATIKALV-------SRCRAKATASQSSAQWGRITTETAI---------------- 282
Query: 279 SRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSS-------TSLQR 331
QL+GIM V +CWSP+L+++ + +S T Q+
Sbjct: 283 -------------------QLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQK 323
Query: 332 P---LFLAVRLASWNQILDPWVYILLRQAVLRQLLRL 365
+AVRLAS NQILDPWVY+LLR+ +LR+ ++
Sbjct: 324 ECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI 360
>gi|38505184 prostaglandin E receptor 3, subtype EP3 isoform 7 [Homo
sapiens]
Length = 365
Score = 162 bits (409), Expect = 7e-40
Identities = 127/393 (32%), Positives = 174/393 (44%), Gaps = 85/393 (21%)
Query: 4 CGPLNLSLAGEATTCAAPWVPNTSAV--------PPSG-----ASPALPIFSMTLGAVSN 50
C LN S G W P SA P SG S A PI + G V N
Sbjct: 14 CTRLNHSYTGM-------WAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGN 66
Query: 51 LLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRA-----P 105
LA+ L++++ R +R + FLL + L TDL G ++ +V+ +Y + + P
Sbjct: 67 ALAMLLVSRSYRRRESKRKKS-FLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDP 125
Query: 106 AGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVA 165
+G C F G M FGL L + MAVER + + P +A+ + R L V
Sbjct: 126 SGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAV 185
Query: 166 LAVALLPLARVGRYELQYPGTWCFIGLGPPG-------GWRQALLAGLFASLGLVALLAA 218
LA ALLP+ VG+Y +Q+PGTWCFI G G W A FA LGL+AL
Sbjct: 186 LAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVT 245
Query: 219 LVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGG 278
CN + AL+ SR A+ S +WG +A
Sbjct: 246 FSCNLATIKALV-------SRCRAKATASQSSAQWGRITTETAI---------------- 282
Query: 279 SRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSS-------TSLQR 331
QL+GIM V +CWSP+L+++ + +S T Q+
Sbjct: 283 -------------------QLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQK 323
Query: 332 P---LFLAVRLASWNQILDPWVYILLRQAVLRQ 361
+AVRLAS NQILDPWVY+LLR+ +LR+
Sbjct: 324 ECNFFLIAVRLASLNQILDPWVYLLLRKILLRK 356
>gi|4506259 prostaglandin E receptor 4, subtype EP4 [Homo sapiens]
Length = 488
Score = 130 bits (327), Expect = 2e-30
Identities = 107/355 (30%), Positives = 165/355 (46%), Gaps = 25/355 (7%)
Query: 19 AAPWVPNTSAVPPS--GASPALPIFSMTLGAVSNLLALALLAQAAGRLRRRRSAATFLLF 76
+ P V +++++ P + +P G V NL+A+ +L ++ R+ + TF
Sbjct: 2 STPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKS----RKEQKETTFYTL 57
Query: 77 VASLLATDLAGHVIPGALVLRLYTAGRAPAGGA-CHFLGGCMVFFGLCPLLLGCGMAVER 135
V L TDL G ++ + + Y G+ P G C + ++FF L L + C M+VER
Sbjct: 58 VCGLAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVER 117
Query: 136 CVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPP 195
+ + ++ V A L L AV A + LP +G LQYP TWCFI
Sbjct: 118 YLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFID-WTT 176
Query: 196 GGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGA 255
A + ++A +LA ++CN L ALLR R+ RR + G +
Sbjct: 177 NVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMH-RQFMRR--TSLGTEQH----- 228
Query: 256 HGPRSASASSASSIASASTF--FGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPM 313
H +AS +S A++ R S RR +++MV L+ +V IC P+
Sbjct: 229 HAAAAASVASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPL 288
Query: 314 LVLVALAVGGWSSTSLQR-----PLFLAVRLASWNQILDPWVYILLRQAVLRQLL 363
+V V V SL+R P A+R+AS N ILDPW+YILLR+ VL + +
Sbjct: 289 VVRV--FVNQLYQPSLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAI 341
>gi|31881630 prostaglandin E receptor 2 (subtype EP2), 53kDa [Homo
sapiens]
Length = 358
Score = 127 bits (320), Expect = 1e-29
Identities = 109/349 (31%), Positives = 159/349 (45%), Gaps = 51/349 (14%)
Query: 31 PSGASPALPIFSMTLGAVSNLLALALLAQ--------AAGRLRRRRSAATFLLFVASLLA 82
P G SPA+ + G + NL+ALALLA+ +AGR R S + F + V L+
Sbjct: 20 PPGESPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGR---RSSLSLFHVLVTELVF 76
Query: 83 TDLAGHVIPGALVLRLYTAGR-----APAGGACHFLGGCMVFFGLCPLLLGCGMAVERCV 137
TDL G + +VL Y + AP AC + M FF L +L+ MA+ER +
Sbjct: 77 TDLLGTCLISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMALERYL 136
Query: 138 GVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGG 197
+ P + RVS + L + AV+L LPL G+Y PGTWCFI G
Sbjct: 137 SIGHPYFYQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHG---- 192
Query: 198 WRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHG 257
R A L L+A+L L+ +++ L CN L L+R R R R P+ G G G
Sbjct: 193 -RTAYLQ-LYATLLLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGS------GRGG 244
Query: 258 PRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLV 317
P G+R G R + A + + + L + + +C P +
Sbjct: 245 P-------------------GARRRGE-RVSMAEETDHLILLAIMTITFAVCSLPFTI-- 282
Query: 318 ALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLL 366
A +S+ ++ A+R S N I+DPWV+ +LR VLR + +L
Sbjct: 283 -FAYMNETSSRKEKWDLQALRFLSINSIIDPWVFAILRPPVLRLMRSVL 330
>gi|4506263 prostaglandin I2 (prostacyclin) receptor (IP) [Homo
sapiens]
Length = 386
Score = 114 bits (284), Expect = 2e-25
Identities = 106/337 (31%), Positives = 146/337 (43%), Gaps = 60/337 (17%)
Query: 36 PALPIFSMTLGAVSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALV 95
PA G V N LAL +L+ RR + F + V L ATDL G V
Sbjct: 17 PATSTLMFVAGVVGNGLALGILSA-----RRPARPSAFAVLVTGLAATDLLGTSFLSPAV 71
Query: 96 LRLYTA-----GRAPAGGA-CHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARV 149
Y G A G A C M FFGL +L+ MAVERC+ ++ P L+A
Sbjct: 72 FVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLD 131
Query: 150 SVARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGL--GPPGGWRQALLAGLF 207
ARLAL A+ A + LPL +G+++ PG+WCF+ + PGG A
Sbjct: 132 GPRCARLALPAIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGG-----AAFSL 186
Query: 208 ASLGLVALLAALV--CNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASS 265
A GLVALL A + CN L+L R +R++ +R G+ GPR
Sbjct: 187 AYAGLVALLVAAIFLCNGSVTLSLCR-MYRQQ------------KRHQGSLGPRP----- 228
Query: 266 ASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWS 325
R +V+ + L + VV +C P+ +
Sbjct: 229 ---------------------RTGEDEVDHLILLALMTVVMAVCSLPLTIRCFTQAVAPD 267
Query: 326 STSLQRPLFLAVRLASWNQILDPWVYILLRQAVLRQL 362
S+S L LA R ++N ILDPWV+IL R+AV ++L
Sbjct: 268 SSSEMGDL-LAFRFYAFNPILDPWVFILFRKAVFQRL 303
>gi|28466969 prostaglandin D2 receptor [Homo sapiens]
Length = 359
Score = 92.0 bits (227), Expect = 8e-19
Identities = 96/355 (27%), Positives = 145/355 (40%), Gaps = 51/355 (14%)
Query: 25 NTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQAA----GRLRRRRSAATFLLFVASL 80
NT++V G S + + G + NLLAL LLA++ R R + F + V L
Sbjct: 10 NTTSVE-KGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGL 68
Query: 81 LATDLAGHVIPGALVLRLYTAGR-----APA--GGACHFLGGCMVFFGLCPLLLGCGMAV 133
TDL G + +VL Y R APA C M FFGL L MA+
Sbjct: 69 TVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMAL 128
Query: 134 ERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLG 193
E + + P + +++ L V+A +LA LP G++ PGTWCFI +
Sbjct: 129 ECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMV 188
Query: 194 PPGGWRQAL-LAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRR 252
G L + L++SL + +LA ++CN L + L A RR R
Sbjct: 189 HEEGSLSVLGYSVLYSSLMALLVLATVLCN-LGAMRNLYAMHRRLQRH------------ 235
Query: 253 WGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSP 312
PRS + A A R A +E + L+ + +++ +
Sbjct: 236 -----PRSCTRDCAEPRA-------------DGREASPQPLEELDHLLLLALMTVLFTMC 277
Query: 313 MLVLVALAVGG-------WSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLR 360
L ++ A G + TS + A+R S I+DPW++I+ R V R
Sbjct: 278 SLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFR 332
>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
Length = 408
Score = 58.9 bits (141), Expect = 8e-09
Identities = 105/384 (27%), Positives = 138/384 (35%), Gaps = 43/384 (11%)
Query: 20 APWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQAAGRLR-------RRRSAAT 72
APW + P + + LP LLALA+LA G L R
Sbjct: 12 APWPDLPTLAPNTANTSGLPGVPWEAALAGALLALAVLATVGGNLLVIVAIAWTPRLQTM 71
Query: 73 FLLFVASLLATDLAGH--VIPGALVLRLYTAGRAPAGGA-CHFLGGCMVFFGLCPLLLGC 129
+FV SL A DL V+P A L L G P G C V + C
Sbjct: 72 TNVFVTSLAAADLVMGLLVVPPAATLAL--TGHWPLGATGCELWTSVDVLCVTASIETLC 129
Query: 130 GMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLA----RVG----RYEL 181
+AV+R + VT PL + A V+ AR A+ V V+ AV+ P+ RVG
Sbjct: 130 ALAVDRYLAVTNPLRYGALVTKRCARTAVVLVWVVSAAVSFAPIMSQWWRVGADAEAQRC 189
Query: 182 QYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRP 241
C P + ++ L ++ + A + L LLR R
Sbjct: 190 HSNPRCCAFASNMPYVLLSSSVSFYLPLLVMLFVYARVFVVATRQLRLLRGELGRF---- 245
Query: 242 PPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVG 301
PP P + R A P A A G R AR + + L
Sbjct: 246 PPEESPPAPSRSLAPAPVGTCAPPEGVPAC------GRR---PARLLPLREHRALCTLGL 296
Query: 302 IMVVSCICWSP-MLVLVALAVGGWSSTSLQRPLFLAVR-LASWNQILDPWVYIL---LRQ 356
IM +CW P L V A+GG + + P FLA+ L N +P +Y R
Sbjct: 297 IMGTFTLCWLPFFLANVLRALGG--PSLVPGPAFLALNWLGYANSAFNPLIYCRSPDFRS 354
Query: 357 AVLRQLLRL---LPPRAGAKGGPA 377
A R L R LPP A PA
Sbjct: 355 AFRRLLCRCGRRLPPEPCAAARPA 378
>gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 52.0 bits (123), Expect = 9e-07
Identities = 83/346 (23%), Positives = 133/346 (38%), Gaps = 48/346 (13%)
Query: 37 ALPIFSMTLGA---VSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGA 93
A+ + S+TLG + NLL L ++ + LR R S F+ SL DL G VI
Sbjct: 118 AIAVLSLTLGTFTVLENLLVLCVILHSRS-LRCRPSYH----FIGSLAVADLLGSVIFVY 172
Query: 94 LVLRLYTAGRAPAGGACHF-LGGCMVFF--GLCPLLLGCGMAVERCVGVTRPLLHAARVS 150
+ + R + F LGG F + L L A++R + + RPL + V+
Sbjct: 173 SFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFL---TAIDRYISIHRPLAYKRIVT 229
Query: 151 VARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASL 210
+A +A + +A+ +A+LPL +LQ + F + L +
Sbjct: 230 RPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDE---------TYLMFWI 280
Query: 211 GLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIA 270
G+ ++L + A + W+ S H R + SI
Sbjct: 281 GVTSVLLLFIV-----YAYMYILWKAHS-----------------HAVRMIQRGTQKSII 318
Query: 271 SASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQ 330
T G +AR D+ + LV I+VV ICW P+L ++ V G + ++
Sbjct: 319 -IHTSEDGKVQVTRPDQARM-DIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIK 376
Query: 331 RPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGP 376
L N ++P +Y LR LR R + P P
Sbjct: 377 TVFAFCSMLCLLNSTVNPIIY-ALRSKDLRHAFRSMFPSCEGTAQP 421
>gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 52.0 bits (123), Expect = 9e-07
Identities = 83/346 (23%), Positives = 133/346 (38%), Gaps = 48/346 (13%)
Query: 37 ALPIFSMTLGA---VSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGA 93
A+ + S+TLG + NLL L ++ + LR R S F+ SL DL G VI
Sbjct: 118 AIAVLSLTLGTFTVLENLLVLCVILHSRS-LRCRPSYH----FIGSLAVADLLGSVIFVY 172
Query: 94 LVLRLYTAGRAPAGGACHF-LGGCMVFF--GLCPLLLGCGMAVERCVGVTRPLLHAARVS 150
+ + R + F LGG F + L L A++R + + RPL + V+
Sbjct: 173 SFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFL---TAIDRYISIHRPLAYKRIVT 229
Query: 151 VARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASL 210
+A +A + +A+ +A+LPL +LQ + F + L +
Sbjct: 230 RPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDE---------TYLMFWI 280
Query: 211 GLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIA 270
G+ ++L + A + W+ S H R + SI
Sbjct: 281 GVTSVLLLFIV-----YAYMYILWKAHS-----------------HAVRMIQRGTQKSII 318
Query: 271 SASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQ 330
T G +AR D+ + LV I+VV ICW P+L ++ V G + ++
Sbjct: 319 -IHTSEDGKVQVTRPDQARM-DIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIK 376
Query: 331 RPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGP 376
L N ++P +Y LR LR R + P P
Sbjct: 377 TVFAFCSMLCLLNSTVNPIIY-ALRSKDLRHAFRSMFPSCEGTAQP 421
>gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 52.0 bits (123), Expect = 9e-07
Identities = 83/346 (23%), Positives = 133/346 (38%), Gaps = 48/346 (13%)
Query: 37 ALPIFSMTLGA---VSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGA 93
A+ + S+TLG + NLL L ++ + LR R S F+ SL DL G VI
Sbjct: 118 AIAVLSLTLGTFTVLENLLVLCVILHSRS-LRCRPSYH----FIGSLAVADLLGSVIFVY 172
Query: 94 LVLRLYTAGRAPAGGACHF-LGGCMVFF--GLCPLLLGCGMAVERCVGVTRPLLHAARVS 150
+ + R + F LGG F + L L A++R + + RPL + V+
Sbjct: 173 SFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFL---TAIDRYISIHRPLAYKRIVT 229
Query: 151 VARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASL 210
+A +A + +A+ +A+LPL +LQ + F + L +
Sbjct: 230 RPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDE---------TYLMFWI 280
Query: 211 GLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIA 270
G+ ++L + A + W+ S H R + SI
Sbjct: 281 GVTSVLLLFIV-----YAYMYILWKAHS-----------------HAVRMIQRGTQKSII 318
Query: 271 SASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQ 330
T G +AR D+ + LV I+VV ICW P+L ++ V G + ++
Sbjct: 319 -IHTSEDGKVQVTRPDQARM-DIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIK 376
Query: 331 RPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGP 376
L N ++P +Y LR LR R + P P
Sbjct: 377 TVFAFCSMLCLLNSTVNPIIY-ALRSKDLRHAFRSMFPSCEGTAQP 421
>gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 52.0 bits (123), Expect = 9e-07
Identities = 83/346 (23%), Positives = 133/346 (38%), Gaps = 48/346 (13%)
Query: 37 ALPIFSMTLGA---VSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGA 93
A+ + S+TLG + NLL L ++ + LR R S F+ SL DL G VI
Sbjct: 118 AIAVLSLTLGTFTVLENLLVLCVILHSRS-LRCRPSYH----FIGSLAVADLLGSVIFVY 172
Query: 94 LVLRLYTAGRAPAGGACHF-LGGCMVFF--GLCPLLLGCGMAVERCVGVTRPLLHAARVS 150
+ + R + F LGG F + L L A++R + + RPL + V+
Sbjct: 173 SFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFL---TAIDRYISIHRPLAYKRIVT 229
Query: 151 VARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASL 210
+A +A + +A+ +A+LPL +LQ + F + L +
Sbjct: 230 RPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDE---------TYLMFWI 280
Query: 211 GLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIA 270
G+ ++L + A + W+ S H R + SI
Sbjct: 281 GVTSVLLLFIV-----YAYMYILWKAHS-----------------HAVRMIQRGTQKSII 318
Query: 271 SASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQ 330
T G +AR D+ + LV I+VV ICW P+L ++ V G + ++
Sbjct: 319 -IHTSEDGKVQVTRPDQARM-DIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIK 376
Query: 331 RPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGP 376
L N ++P +Y LR LR R + P P
Sbjct: 377 TVFAFCSMLCLLNSTVNPIIY-ALRSKDLRHAFRSMFPSCEGTAQP 421
>gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 52.0 bits (123), Expect = 9e-07
Identities = 83/346 (23%), Positives = 133/346 (38%), Gaps = 48/346 (13%)
Query: 37 ALPIFSMTLGA---VSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGA 93
A+ + S+TLG + NLL L ++ + LR R S F+ SL DL G VI
Sbjct: 118 AIAVLSLTLGTFTVLENLLVLCVILHSRS-LRCRPSYH----FIGSLAVADLLGSVIFVY 172
Query: 94 LVLRLYTAGRAPAGGACHF-LGGCMVFF--GLCPLLLGCGMAVERCVGVTRPLLHAARVS 150
+ + R + F LGG F + L L A++R + + RPL + V+
Sbjct: 173 SFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFL---TAIDRYISIHRPLAYKRIVT 229
Query: 151 VARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASL 210
+A +A + +A+ +A+LPL +LQ + F + L +
Sbjct: 230 RPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDE---------TYLMFWI 280
Query: 211 GLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIA 270
G+ ++L + A + W+ S H R + SI
Sbjct: 281 GVTSVLLLFIV-----YAYMYILWKAHS-----------------HAVRMIQRGTQKSII 318
Query: 271 SASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQ 330
T G +AR D+ + LV I+VV ICW P+L ++ V G + ++
Sbjct: 319 -IHTSEDGKVQVTRPDQARM-DIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIK 376
Query: 331 RPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGP 376
L N ++P +Y LR LR R + P P
Sbjct: 377 TVFAFCSMLCLLNSTVNPIIY-ALRSKDLRHAFRSMFPSCEGTAQP 421
>gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]
Length = 439
Score = 52.0 bits (123), Expect = 9e-07
Identities = 83/346 (23%), Positives = 133/346 (38%), Gaps = 48/346 (13%)
Query: 37 ALPIFSMTLGA---VSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGA 93
A+ + S+TLG + NLL L ++ + LR R S F+ SL DL G VI
Sbjct: 85 AIAVLSLTLGTFTVLENLLVLCVILHSRS-LRCRPSYH----FIGSLAVADLLGSVIFVY 139
Query: 94 LVLRLYTAGRAPAGGACHF-LGGCMVFF--GLCPLLLGCGMAVERCVGVTRPLLHAARVS 150
+ + R + F LGG F + L L A++R + + RPL + V+
Sbjct: 140 SFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFL---TAIDRYISIHRPLAYKRIVT 196
Query: 151 VARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASL 210
+A +A + +A+ +A+LPL +LQ + F + L +
Sbjct: 197 RPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDE---------TYLMFWI 247
Query: 211 GLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIA 270
G+ ++L + A + W+ S H R + SI
Sbjct: 248 GVTSVLLLFIV-----YAYMYILWKAHS-----------------HAVRMIQRGTQKSII 285
Query: 271 SASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQ 330
T G +AR D+ + LV I+VV ICW P+L ++ V G + ++
Sbjct: 286 -IHTSEDGKVQVTRPDQARM-DIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIK 343
Query: 331 RPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGP 376
L N ++P +Y LR LR R + P P
Sbjct: 344 TVFAFCSMLCLLNSTVNPIIY-ALRSKDLRHAFRSMFPSCEGTAQP 388
>gi|23592220 G protein-coupled receptor 26 [Homo sapiens]
Length = 337
Score = 50.4 bits (119), Expect = 3e-06
Identities = 55/202 (27%), Positives = 86/202 (42%), Gaps = 10/202 (4%)
Query: 38 LPIFSMTLGAVSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLR 97
L + +M + +SN L L L +A +RR+ A LF +L +L V+ L L
Sbjct: 11 LLVGTMGVSLLSNALVLLCLLHSAD-IRRQAPA----LFTLNLTCGNLLCTVVNMPLTLA 65
Query: 98 LYTAGRAPAGGA-CHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARL 156
A R PAG C F +L ++++R V V PL + A++ + A L
Sbjct: 66 GVVAQRQPAGDRLCRLAAFLDTFLAANSMLSMAALSIDRWVAVVFPLSYRAKMRLRDAAL 125
Query: 157 ALAA--VAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVA 214
+A + A+ A L L+ +G ++L T C P R A+ G F +L +
Sbjct: 126 MVAYTWLHALTFPAAALALSWLGFHQLYASCTLC--SRRPDERLRFAVFTGAFHALSFLL 183
Query: 215 LLAALVCNTLSGLALLRARWRR 236
L C L L + R +R
Sbjct: 184 SFVVLCCTYLKVLKVARFHCKR 205
>gi|4557345 arginine vasopressin receptor 2 isoform 1 [Homo sapiens]
Length = 371
Score = 47.0 bits (110), Expect = 3e-05
Identities = 87/377 (23%), Positives = 137/377 (36%), Gaps = 66/377 (17%)
Query: 15 ATTCAAPWVPNTSAVP-------------PSGASPALPIFSMTLGAV--SNLLALALLAQ 59
+TT A P P+ ++P P A L + S+ AV SN L LA LA
Sbjct: 5 STTSAVPGHPSLPSLPSNSSQERPLDTRDPLLARAELALLSIVFVAVALSNGLVLAALA- 63
Query: 60 AAGRLRRRRSAATFLLFVASLLATDLAG---HVIPGALVLRLYTAGRAPAGGACHFLGGC 116
R RR A +F+ L DLA V+P L + R P C +
Sbjct: 64 ---RRGRRGHWAPIHVFIGHLCLADLAVALFQVLP-QLAWKATDRFRGP-DALCRAVKYL 118
Query: 117 MVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARV 176
+ + M ++R + RP+L S A + A +L ++L L
Sbjct: 119 QMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIF 178
Query: 177 GRYELQYPG--TWCFIGLGPPGGWRQ-----ALLAGLFASLGLVALLAALVCNTLSGLAL 229
+ ++ T C+ P G R AL+ + +LG+ A + + L
Sbjct: 179 AQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHASLV- 237
Query: 230 LRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRAR 289
P P+ P RRR G R+ S + +++A
Sbjct: 238 -----------PGPSERPGGRRR----GRRTGSPGEGAHVSAAVA--------------- 267
Query: 290 AHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPW 349
+ V + I+VV +CW+P ++ A + P L + LAS N +PW
Sbjct: 268 ----KTVRMTLVIVVVYVLCWAPFFLVQLWAAWDPEAPLEGAPFVLLMLLASLNSCTNPW 323
Query: 350 VYILLRQAVLRQLLRLL 366
+Y +V +L LL
Sbjct: 324 IYASFSSSVSSELRSLL 340
>gi|4557265 beta-1-adrenergic receptor [Homo sapiens]
Length = 477
Score = 44.3 bits (103), Expect = 2e-04
Identities = 42/170 (24%), Positives = 70/170 (41%), Gaps = 9/170 (5%)
Query: 12 AGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQAAGRL------- 64
A A P P S +PP+ SP P+ + L+AL +L AG +
Sbjct: 26 AATAARLLVPASPPASLLPPASESPE-PLSQQWTAGMGLLMALIVLLIVAGNVLVIVAIA 84
Query: 65 RRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGA-CHFLGGCMVFFGLC 123
+ R LF+ SL + DL ++ + GR G C V
Sbjct: 85 KTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTA 144
Query: 124 PLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPL 173
+ C +A++R + +T P + + ++ ARAR + V A++ V+ LP+
Sbjct: 145 SIETLCVIALDRYLAITSPFRYQSLLTRARARGLVCTVWAISALVSFLPI 194
>gi|13540517 endothelial differentiation, sphingolipid
G-protein-coupled receptor, 8 [Homo sapiens]
Length = 398
Score = 44.3 bits (103), Expect = 2e-04
Identities = 96/360 (26%), Positives = 134/360 (37%), Gaps = 76/360 (21%)
Query: 47 AVSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDL-------AGHVIPGALVLRLY 99
AV + L LA R R A L + SL +DL A ++ G L L+L
Sbjct: 45 AVCAFIVLENLAVLLVLGRHPRFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLS 104
Query: 100 TA-GRAPAGGACHFLGGCMVFFGLCPLLLGC-GMAVERCVGVTRPLLHAARVSVARARLA 157
A A GG VF L +L +A+ER + + R A VS LA
Sbjct: 105 PALWFAREGG---------VFVALTASVLSLLAIALERSLTMARR--GPAPVSSRGRTLA 153
Query: 158 LAAVA-AVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAG---LFASLGLV 213
+AA A V+L + LLP W +G L A LF L V
Sbjct: 154 MAAAAWGVSLLLGLLPALG-----------WNCLGRLDACSTVLPLYAKAYVLFCVLAFV 202
Query: 214 ALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASAS 273
+LAA+ +RA RR RP A +R R PRS + S+
Sbjct: 203 GILAAICALYARIYCQVRANARRLPARPGTAGTTSTRAR---RKPRSLALLRTLSV---- 255
Query: 274 TFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTS---LQ 330
+++ CW P+ +L+ L V + T LQ
Sbjct: 256 ----------------------------VLLAFVACWGPLFLLLLLDVACPARTCPVLLQ 287
Query: 331 RPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLL-PPRAGAKGGPAGLGLTPSAWEAS 389
FL + +A N +L+P +Y L + + LLRL+ R P+G + SA EAS
Sbjct: 288 ADPFLGLAMA--NSLLNPIIYTLTNRDLRHALLRLVCCGRHSCGRDPSGSQQSASAAEAS 345
>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
Length = 572
Score = 43.9 bits (102), Expect = 3e-04
Identities = 94/386 (24%), Positives = 148/386 (38%), Gaps = 54/386 (13%)
Query: 5 GPLNLSLAGEATTCAAPWVPNTSA------VPPSGASPALPIFSMTLGAVSNLLALALLA 58
G N S AGE + A N +A V G + + + L AV+ L + L
Sbjct: 62 GEDNRSSAGEPGSAGAGGDVNGTAAVGGLVVSAQGVGVGVFLAAFILMAVAGNLLVILSV 121
Query: 59 QAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGAL---VLRLYTAGRAPAGGACHFLGG 115
L+ + L VA LL L+ V+P + VL + GRA C
Sbjct: 122 ACNRHLQTVTNYFIVNLAVADLL---LSATVLPFSATMEVLGFWAFGRA----FCDVWAA 174
Query: 116 CMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLAR 175
V +L C ++V+R VGV L + A ++ +A LA + VAL V++ PL
Sbjct: 175 VDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWVVALVVSVGPLL- 233
Query: 176 VGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTL----SGLALLR 231
++ P F G+ G+ A+ + + + +A++ + C S L
Sbjct: 234 --GWKEPVPPDERFCGITEEAGY--AVFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLE 289
Query: 232 ARWRRRSRRPP----------PASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRS 281
A +R + A+G D GAHG RS A TF RS
Sbjct: 290 AGVKRERGKASEVVLRIHCRGAATGAD-----GAHGMRS---------AKGHTF----RS 331
Query: 282 SGSARRARAHDVEMVGQLVGIMV-VSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLA 340
S S R + + + + I+V V +CW P ++ L + + L
Sbjct: 332 SLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVIFWLG 391
Query: 341 SWNQILDPWVYILLRQAVLRQLLRLL 366
+N ++P +Y + R LRLL
Sbjct: 392 YFNSCVNPLIYPCSSREFKRAFLRLL 417
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.136 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,725,717
Number of Sequences: 37866
Number of extensions: 682203
Number of successful extensions: 4926
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 77
Number of HSP's successfully gapped in prelim test: 102
Number of HSP's that attempted gapping in prelim test: 4679
Number of HSP's gapped (non-prelim): 288
length of query: 402
length of database: 18,247,518
effective HSP length: 105
effective length of query: 297
effective length of database: 14,271,588
effective search space: 4238661636
effective search space used: 4238661636
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.