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Search of human proteins with 38327634
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
sapiens]
(670 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi... 1325 0.0
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi... 378 e-105
gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo sapi... 285 1e-76
gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1 ... 280 2e-75
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 222 8e-58
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 221 2e-57
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi... 196 6e-50
gi|20336298 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 2 ... 192 1e-48
gi|13129006 nucleolar protein GU2 [Homo sapiens] 191 2e-48
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi... 189 5e-48
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ... 184 2e-46
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 184 3e-46
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 184 3e-46
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 183 4e-46
gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 181 1e-45
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 180 4e-45
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 178 2e-44
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 178 2e-44
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 176 6e-44
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 174 2e-43
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 174 3e-43
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 174 3e-43
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi... 172 1e-42
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 167 2e-41
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 167 3e-41
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 166 5e-41
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 166 5e-41
gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 165 1e-40
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi... 165 1e-40
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 162 7e-40
>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
sapiens]
Length = 670
Score = 1325 bits (3428), Expect = 0.0
Identities = 670/670 (100%), Positives = 670/670 (100%)
Query: 1 MSHLPMKLLRKKIEKRNLKLRQRNLKFQGASNLTLSETQNGDVSEETMGSRKVKKSKQKP 60
MSHLPMKLLRKKIEKRNLKLRQRNLKFQGASNLTLSETQNGDVSEETMGSRKVKKSKQKP
Sbjct: 1 MSHLPMKLLRKKIEKRNLKLRQRNLKFQGASNLTLSETQNGDVSEETMGSRKVKKSKQKP 60
Query: 61 MNVGLSETQNGGMSQEAVGNIKVTKSPQKSTVLTNGEAAMQSSNSESKKKKKKKRKMVND 120
MNVGLSETQNGGMSQEAVGNIKVTKSPQKSTVLTNGEAAMQSSNSESKKKKKKKRKMVND
Sbjct: 61 MNVGLSETQNGGMSQEAVGNIKVTKSPQKSTVLTNGEAAMQSSNSESKKKKKKKRKMVND 120
Query: 121 AEPDTKKAKTENKGKSEEESAETTKETENNVEKPDNDEDESEVPSLPLGLTGAFEDTSFA 180
AEPDTKKAKTENKGKSEEESAETTKETENNVEKPDNDEDESEVPSLPLGLTGAFEDTSFA
Sbjct: 121 AEPDTKKAKTENKGKSEEESAETTKETENNVEKPDNDEDESEVPSLPLGLTGAFEDTSFA 180
Query: 181 SLCNLVNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVEL 240
SLCNLVNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVEL
Sbjct: 181 SLCNLVNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVEL 240
Query: 241 IVKLRFMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGN 300
IVKLRFMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGN
Sbjct: 241 IVKLRFMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGN 300
Query: 301 GINIIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQT 360
GINIIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQT
Sbjct: 301 GINIIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQT 360
Query: 361 MLFSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFL 420
MLFSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFL
Sbjct: 361 MLFSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFL 420
Query: 421 KKNRKKKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLL 480
KKNRKKKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLL
Sbjct: 421 KKNRKKKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLL 480
Query: 481 CTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLRY 540
CTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLRY
Sbjct: 481 CTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLRY 540
Query: 541 LKQSKVPLSEFDFSWSKISDIQSQLEKLIEKNYFLHKSAQEAYKSYIRAYDSHSLKQIFN 600
LKQSKVPLSEFDFSWSKISDIQSQLEKLIEKNYFLHKSAQEAYKSYIRAYDSHSLKQIFN
Sbjct: 541 LKQSKVPLSEFDFSWSKISDIQSQLEKLIEKNYFLHKSAQEAYKSYIRAYDSHSLKQIFN 600
Query: 601 VNNLNLPQVALSFGFKVPPFVDLNVNSNEGKQKKRGGGGGFGYQKTKKVEKSKIFKHISK 660
VNNLNLPQVALSFGFKVPPFVDLNVNSNEGKQKKRGGGGGFGYQKTKKVEKSKIFKHISK
Sbjct: 601 VNNLNLPQVALSFGFKVPPFVDLNVNSNEGKQKKRGGGGGFGYQKTKKVEKSKIFKHISK 660
Query: 661 KSSDSRQFSH 670
KSSDSRQFSH
Sbjct: 661 KSSDSRQFSH 670
>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
sapiens]
Length = 875
Score = 378 bits (971), Expect = e-105
Identities = 212/505 (41%), Positives = 315/505 (62%), Gaps = 10/505 (1%)
Query: 121 AEPDTKKAKTENKGKSEEESAETTKETENNVEKPDNDEDESEVPSLPLGLT--GAFEDTS 178
A PD ++ K K K+ ++KP+ + + L E T
Sbjct: 12 ARPDPVRSFNRWK-KKHSHRQNKKKQLRKQLKKPEWQVERESISRLMQNYEKINVNEITR 70
Query: 179 FASLCNLVNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAV 238
F+ +++ TLK ++E + +TEIQ ++I L+G+D+L AAKTGSGKTLAFL+P +
Sbjct: 71 FSDFP--LSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVL 128
Query: 239 ELIVKLRFMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKL 298
E + +L++ +G GVLI+SPTRELA QTF VL+++ +H + GLI+GG + EA+++
Sbjct: 129 EALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERI 188
Query: 299 GNGINIIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRR 358
N INI+V TPGRLL HM T F +LQ LV+DEADRILD+GF + + +I+ LP +R
Sbjct: 189 -NNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIENLPKKR 247
Query: 359 QTMLFSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFT 418
QT+LFSATQT+ V+DLAR+SL K P YV V + +T LEQ Y+VC +++ +L++
Sbjct: 248 QTLLFSATQTKSVKDLARLSL-KNPEYVWVHEKAKYSTPATLEQNYIVCELQQKISVLYS 306
Query: 419 FLKKNRKKKLMVFFSSCMSVKYHYELLNYI--DLPVLAIHGKQKQNKRTTTFFQFCNADS 476
FL+ + KKK +VFFSSC V+Y Y + + + +LA+HG+Q+Q +R + +F +
Sbjct: 307 FLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEFVRKRA 366
Query: 477 GTLLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELG 536
L TD+AARGLD P V+W++Q+D P+D YIHR GRTAR G ALLIL P E
Sbjct: 367 AVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTAR-YKEDGEALLILLPSEKA 425
Query: 537 FLRYLKQSKVPLSEFDFSWSKISDIQSQLEKLIEKNYFLHKSAQEAYKSYIRAYDSHSLK 596
++ L Q KVP+ E + K+ D+Q +LE ++ ++ L + AQ + SY+R+ K
Sbjct: 426 MVQQLLQKKVPVKEIKINPEKLIDVQKKLESILAQDQDLKERAQRCFVSYVRSVYLMKDK 485
Query: 597 QIFNVNNLNLPQVALSFGFKVPPFV 621
++F+V+ L +P+ ALS G V P V
Sbjct: 486 EVFDVSKLPIPEYALSLGLAVAPRV 510
>gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo
sapiens]
Length = 600
Score = 285 bits (729), Expect = 1e-76
Identities = 186/536 (34%), Positives = 295/536 (55%), Gaps = 50/536 (9%)
Query: 178 SFASLCNLVNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPA 237
S+ SL ++ L A++E+GF MT +Q +I + +D+ A A TGSGKTLAF+IP
Sbjct: 8 SWESLPVPLHPQVLGALRELGFPYMTPVQSATIPLFMRNKDVAAEAVTGSGKTLAFVIPI 67
Query: 238 VELIVKLRF-MPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLI-MGGSNRSAEA 295
+E++++ + ++ G +I++PTRELA+Q VL H ++ +GG N +
Sbjct: 68 LEILLRREEKLKKSQVGAIIITPTRELAIQIDEVLSHFTKHFPEFSQILWIGGRNPGEDV 127
Query: 296 QKLGN-GINIIVATPGRLLDHMQNTPGFM-----YKNLQCLVIDEADRILDVGFEEELKQ 349
++ G NIIVATPGRL D + + ++L LV+DEADR+LD+GFE +
Sbjct: 128 ERFKQQGGNIIVATPGRLEDMFRRKAEGLDLASCVRSLDVLVLDEADRLLDMGFEASINT 187
Query: 350 IIKLLPTRRQTMLFSATQTRKVEDLARISLKKEPLYV-----GVDDDKANATVDGLEQGY 404
I++ LP +R+T LFSATQT++VE+L R L+ P+ V GV A T LE Y
Sbjct: 188 ILEFLPKQRRTGLFSATQTQEVENLVRAGLRN-PVRVSVKEKGVAASSAQKTPSRLENYY 246
Query: 405 VVCPSEKRFLLLFTFLKKNRKKKLMVFFSSCMSVKYHYELLNYI--DLPVLAIHGKQKQN 462
+VC ++++F L FL+ ++++K +VFFS+C V+Y+ + L + + ++ IHGK K
Sbjct: 247 MVCKADEKFNQLVHFLRNHKQEKHLVFFSTCACVEYYGKALEVLVKGVKIMCIHGKMKY- 305
Query: 463 KRTTTFFQFCNADSGTLLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNG 522
KR F +F SG L+CTDV ARG+DIPEV+W++QYDPP + ++HR GRTAR +G
Sbjct: 306 KRNKIFMEFRKLQSGILVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHG 365
Query: 523 RGHALLILRPEELGFLRYLK-QSKVPLSEFDFSWSKISDIQSQLEKLIEKNYFLHKSAQE 581
G AL+ L P E ++ +L K PL E +D+ +L+ + + + + +
Sbjct: 366 -GSALVFLLPMEESYINFLAINQKCPLQEMK-PQRNTADLLPKLKSMALADRAVFEKGMK 423
Query: 582 AYKSYIRAYDSHSLKQIFNVNNLNLPQVALSF------------GFKVPPFVDLNVNSN- 628
A+ SY++AY H IF + +L+ +A F G + P FV ++VN++
Sbjct: 424 AFVSYVQAYAKHECNLIFRLKDLDFASLARGFALLRMPKMPELRGKQFPDFVPVDVNTDT 483
Query: 629 -----------------EGKQKKRGGGGGFGYQKTKKVEKSKIFKHISKKSSDSRQ 667
+ +++K G + K K K K K KK ++ R+
Sbjct: 484 IPFKDKIREKQRQKLLEQQRREKTENEGRRKFIKNKAWSKQKAKKEKKKKMNEKRK 539
>gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1
[Homo sapiens]
Length = 851
Score = 280 bits (717), Expect = 2e-75
Identities = 207/620 (33%), Positives = 324/620 (52%), Gaps = 100/620 (16%)
Query: 87 PQKSTVLTNGEAAMQSSNSESKKK-KKKKRKMVNDAEPDTKKAKTENKGKSEEESAETTK 145
P K T+ A ++S E+++ K +KM + P T ++ + E + +T+
Sbjct: 147 PAKRRNETSFLPAKKTSVKETQRTFKGNAQKMFS---PKKHSVSTSDRNQEERQCIKTSS 203
Query: 146 ETENNVEKPDNDEDESEVPSLPLGLTGAFEDTSFASLCNLVNENTLKAIKEMGFTNMTEI 205
+NN + P+ + + + AF + +L++ T+ + +M ++MT +
Sbjct: 204 LFKNNPDIPELHRPVVKQVQEKVFTSAAFHELGLHP--HLIS--TINTVLKM--SSMTSV 257
Query: 206 QHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELI--VKLRFMPRNGTGVLILSPTREL 263
Q +SI LLEGRD L ++TGSGKTLA+ IP V+ + ++ + +G L+L PTREL
Sbjct: 258 QKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVPTREL 317
Query: 264 AMQTFGVLKELMTHHVHTY-GLIMGGSNRSAEAQKLGNGINIIVATPGRLLDHMQNTPGF 322
A+Q+F +++L+ G++MGG R +E +L GINI+++TPGRL+DH+++T
Sbjct: 318 ALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKSTKNI 377
Query: 323 MYKNLQCLVIDEADRILDVGFEEELKQIIKLLPT---RRQTMLFSATQTRKVEDLARISL 379
+ L+ LV DEADRILD+GFE+++ I+ + +RQ +L SAT T V LA ISL
Sbjct: 378 HFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLADISL 437
Query: 380 KKEPLYVGVDD---------DKANATV---------------DGLEQGYVVCPSEKRFLL 415
+P+ + V D DKA V + L+Q V PS+ R +
Sbjct: 438 H-DPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVC 496
Query: 416 LFTFLKKNRK----KKLMVFFSSCMSVKYHYELLNY------------------IDLPVL 453
L F+ + K +K++VFFSSC V++HY L + L L
Sbjct: 497 LAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGAPASGQLPSASMRLKFL 556
Query: 454 AIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRV 513
+HG +Q +RT F +F ++ G LLCTDVAARGLD+P+V WIVQY+ P P EYIHR+
Sbjct: 557 RLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPAEYIHRI 616
Query: 514 GRTARGLNGRGHALLILRPEELGFLRYLKQSKVPLSEFDFS----------------W-- 555
GRTAR + G +LLIL P E ++ L K+ +SE W
Sbjct: 617 GRTAR-IGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMEDILCVLTRDDCFKGKRWGA 675
Query: 556 --------SKISDIQSQLEKLIEKNYFLHKS------AQEAYKSYIRAYDSH--SLKQIF 599
+I + + L+ + E ++H S A++A +S+I+AY ++ LK IF
Sbjct: 676 QKSHAVGPQEIRERATVLQTVFED--YVHSSERRVSWAKKALQSFIQAYATYPRELKHIF 733
Query: 600 NVNNLNLPQVALSFGFKVPP 619
+V +L+L VA SFG + P
Sbjct: 734 HVRSLHLGHVAKSFGLRDAP 753
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
Length = 455
Score = 222 bits (566), Expect = 8e-58
Identities = 134/339 (39%), Positives = 205/339 (60%), Gaps = 8/339 (2%)
Query: 186 VNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLR 245
V + +A ++G+T T+IQ ++I L+GRD++ A+TGSGKT AF +P + +++
Sbjct: 31 VTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLET- 89
Query: 246 FMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINII 305
P+ L+L+PTRELA Q + L + +I+GG + +++ L +II
Sbjct: 90 --PQR-LFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHII 146
Query: 306 VATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSA 365
+ATPGRL+DH++NT GF + L+ LV+DEADRIL++ FE E+ +I+K++P R+T LFSA
Sbjct: 147 IATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSA 206
Query: 366 TQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFLKKNRK 425
T T+KV+ L R +L K P+ V TV+ L+Q Y+ PS+ + L L +
Sbjct: 207 TMTKKVQKLQRAAL-KNPVKCAV--SSKYQTVEKLQQYYIFIPSKFKDTYLVYILNELAG 263
Query: 426 KKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVA 485
M+F S+C + + LL + + +HG+ Q+KR + +F LL TDVA
Sbjct: 264 NSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVA 323
Query: 486 ARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTAR-GLNGR 523
+RGLDIP VD +V +D P K+YIHRVGRTAR G +G+
Sbjct: 324 SRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGK 362
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 221 bits (563), Expect = 2e-57
Identities = 180/569 (31%), Positives = 282/569 (49%), Gaps = 42/569 (7%)
Query: 37 ETQNGDVSEE---TMGSRK--VKKSKQKPMNVGLSETQNGGMSQEAVGNIKVTKSPQKST 91
E+ +GD EE +G R+ + K++ N T+ G + V +K
Sbjct: 53 ESDSGDEEEEGPIVLGRRQKALGKNRSADFNPDFVFTEKEGTYDGSWALADVMSQLKKKR 112
Query: 92 VLTNGEAAMQ-------SSNSESKKKKKKKRKMVND-AEPDTKKAKTENKGK-SEEESAE 142
T + ++ + + E+K K +K K + +EP ++ EN + SE+E++E
Sbjct: 113 AATTLDEKIEKVRKKRKTEDKEAKSGKLEKEKEAKEGSEPKEQEDLQENDEEGSEDEASE 172
Query: 143 T--TKETENNVEKPDN----DEDESEVPSLPLGLTGAFEDTS-------FASLCNLVNEN 189
T + EN + K D D + + G G FED S F + NL +
Sbjct: 173 TDYSSADENILTKADTLKVKDRKKKKKKGQEAG--GFFEDASQYDENLSFQDM-NL-SRP 228
Query: 190 TLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPR 249
LKAI MGF T IQ I L G+D+ A A TG+GKT AF +P +E ++ + PR
Sbjct: 229 LLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALPVLERLI---YKPR 285
Query: 250 NG--TGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVA 307
T VL+L PTREL +Q V ++L T L +GG + ++ L +I++A
Sbjct: 286 QAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAPDILIA 345
Query: 308 TPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSATQ 367
TPGRL+DH+ N P F +++ L++DEADR+LD FEE++K+II++ RQTMLFSAT
Sbjct: 346 TPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATM 405
Query: 368 TRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYV-VCPSEK--RFLLLFTFLKKNR 424
T +V+DLA +SL K P+ + V+ + A L Q ++ + P+ + R ++ L +
Sbjct: 406 TDEVKDLASVSL-KNPVRIFVNSNTDVAPF--LRQEFIRIRPNREGDREAIVAALLTRTF 462
Query: 425 KKKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDV 484
+M+F + + LL + L V +HG Q +R +F + L+ TDV
Sbjct: 463 TDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDV 522
Query: 485 AARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLRYLKQS 544
AARGLDI V ++ + P+ K Y+HRVGRTAR L+ E +K +
Sbjct: 523 AARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDERKMLKEIVKAA 582
Query: 545 KVPLSEFDFSWSKISDIQSQLEKLIEKNY 573
K P+ I + ++EK+ + Y
Sbjct: 583 KAPVKARILPQDVILKFRDKIEKMEKDVY 611
>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
sapiens]
Length = 483
Score = 196 bits (498), Expect = 6e-50
Identities = 123/379 (32%), Positives = 214/379 (56%), Gaps = 16/379 (4%)
Query: 195 KEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPRNGTGV 254
+++G T +Q I +LEGRD L AKTGSGKT AF++P ++ + + + G
Sbjct: 18 RQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQKLSEDPY----GIFC 73
Query: 255 LILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVATPGRLLD 314
L+L+PTRELA Q + L +I+GG + A+A +L ++++ATPGRL D
Sbjct: 74 LVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALELSRKPHVVIATPGRLAD 133
Query: 315 HMQNTPGFMYKNLQCLVIDEADRILDVG---FEEELKQIIKLLPTRRQTMLFSATQTRKV 371
H++++ F K ++ LV+DEADR+L+ G F +L+ I+ +P RRQT+LFSAT T +
Sbjct: 134 HLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVPARRQTLLFSATLTDTL 193
Query: 372 EDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFLKKNRKK----K 427
+L ++ + + + +TV+ L+Q Y++ P + + L +++ + +
Sbjct: 194 RELQGLATNQPFFW---EAQAPVSTVEQLDQRYLLVPEKVKDAYLVHLIQRFQDEHEDWS 250
Query: 428 LMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAAR 487
+++F ++C + + +L P +A+H KQ +R +F ++ L+ TDVA+R
Sbjct: 251 IIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAKFKSSIYRILIATDVASR 310
Query: 488 GLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLRYL-KQSKV 546
GLDIP V ++ ++ P PK YIHRVGRTAR +G A+ ++ ++ + + +Q K
Sbjct: 311 GLDIPTVQVVINHNTPGLPKIYIHRVGRTARA-GRQGQAITLVTQYDIHLVHAIEEQIKK 369
Query: 547 PLSEFDFSWSKISDIQSQL 565
L EF +++ I +Q+
Sbjct: 370 KLEEFSVEEAEVLQILTQV 388
>gi|20336298 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 2
[Homo sapiens]
Length = 585
Score = 192 bits (487), Expect = 1e-48
Identities = 144/449 (32%), Positives = 232/449 (51%), Gaps = 63/449 (14%)
Query: 87 PQKSTVLTNGEAAMQSSNSESKKK-KKKKRKMVNDAEPDTKKAKTENKGKSEEESAETTK 145
P K T+ A ++S E+++ K +KM + P T ++ + E + +T+
Sbjct: 147 PAKRRNETSFLPAKKTSVKETQRTFKGNAQKMFS---PKKHSVSTSDRNQEERQCIKTSS 203
Query: 146 ETENNVEKPDNDEDESEVPSLPLGLTGAFEDTSFASLCNLVNENTLKAIKEMGFTNMTEI 205
+NN + P+ + + + AF + +L++ T+ + +M ++MT +
Sbjct: 204 LFKNNPDIPELHRPVVKQVQEKVFTSAAFHELGLHP--HLIS--TINTVLKM--SSMTSV 257
Query: 206 QHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELI--VKLRFMPRNGTGVLILSPTREL 263
Q +SI LLEGRD L ++TGSGKTLA+ IP V+ + ++ + +G L+L PTREL
Sbjct: 258 QKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVPTREL 317
Query: 264 AMQTFGVLKELMTHHVHTY-GLIMGGSNRSAEAQKLGNGINIIVATPGRLLDHMQNTPGF 322
A+Q+F +++L+ G++MGG R +E +L GINI+++TPGRL+DH+++T
Sbjct: 318 ALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKSTKNI 377
Query: 323 MYKNLQCLVIDEADRILDVGFEEELKQIIKLLPT---RRQTMLFSATQTRKVEDLARISL 379
+ L+ LV DEADRILD+GFE+++ I+ + +RQ +L SAT T V LA ISL
Sbjct: 378 HFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLADISL 437
Query: 380 KKEPLYVGVDD---------DKANATV---------------DGLEQGYVVCPSEKRFLL 415
+P+ + V D DKA V + L+Q V PS+ R +
Sbjct: 438 -HDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVC 496
Query: 416 LFTFL----KKNRKKKLMVFFSSCMSVKYHYELL------------------NYIDLPVL 453
L F+ K +K++VFFSSC V++HY L + L L
Sbjct: 497 LAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGAPASGQLPSASMRLKFL 556
Query: 454 AIHGKQKQNKRTTTFFQFCNADSGTLLCT 482
+HG +Q +RT F +F ++ G LLCT
Sbjct: 557 RLHGGMEQEERTAVFQEFSHSRRGVLLCT 585
>gi|13129006 nucleolar protein GU2 [Homo sapiens]
Length = 737
Score = 191 bits (485), Expect = 2e-48
Identities = 152/491 (30%), Positives = 249/491 (50%), Gaps = 43/491 (8%)
Query: 66 SETQNGGMSQEAVGNIKVTKSPQKSTVLTNGEAAMQSSNSESKKKKKKKRKMVNDAEPDT 125
SET+ G++ + + K KS K + + E + E K K +RK + + + D
Sbjct: 45 SETRENGVTDD-LDAPKAKKSKMKEKLNGDTEEGFNRLSDEFSKSHKSRRKDLPNGDIDE 103
Query: 126 KKAKTENKGKSEEESAETTKETENNVEKPDNDEDESEVPSLPLGLTGAFEDTSFASLCNL 185
+ K++ + T K ++N +E+ E + GAF +
Sbjct: 104 YEKKSKRVSSLD---TSTHKSSDNKLEETLTREQKE----------GAFSNFP------- 143
Query: 186 VNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLR 245
++E T+K +K G T + IQ K+ P+ EG+DL+A A+TG+GKT +F IP +E + + +
Sbjct: 144 ISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERLQRNQ 203
Query: 246 FMPRNGTG--VLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGIN 303
+ VL+L+PTRELA Q K++ + GG++ ++ + NGI+
Sbjct: 204 ETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKL--SVACFYGGTSYQSQINHIRNGID 261
Query: 304 IIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLL-----PTRR 358
I+V TPGR+ DH+Q+ + K L+ +V+DE D++LD+GF E+++ II
Sbjct: 262 ILVGTPGRIKDHLQSGRLDLSK-LRHVVLDEVDQMLDLGFAEQVEDIIHESYKTDSEDNP 320
Query: 359 QTMLFSATQTRKVEDLARISLK---KEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLL 415
QT+LFSAT + V +A+ +K ++ VG KA TV+ L + C +R +
Sbjct: 321 QTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLA---IQCHWSQRPAV 377
Query: 416 LFTFLK--KNRKKKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCN 473
+ L+ + + ++F + +V + +I +HG Q++R T F
Sbjct: 378 IGDVLQVYSGSEGRAIIFCETKKNVT-EMAMNPHIKQNAQCLHGDIAQSQREITLKGFRE 436
Query: 474 ADSGTLLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGR-GHALLILRP 532
L+ T+VAARGLDIPEVD ++Q PP D + YIHR GRT R GR G + +P
Sbjct: 437 GSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRA--GRTGICICFYQP 494
Query: 533 EELGFLRYLKQ 543
E G LRY++Q
Sbjct: 495 RERGQLRYVEQ 505
>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
sapiens]
Length = 783
Score = 189 bits (481), Expect = 5e-48
Identities = 155/493 (31%), Positives = 241/493 (48%), Gaps = 35/493 (7%)
Query: 39 QNGDVSEETMGSRKVKKSKQK--PMNVGLSETQNGGMSQEAVGNIKVTKSPQKSTVLTNG 96
+ + SE M S K KK+K+K P +S ++ KV S K +T
Sbjct: 60 KKAEPSEVDMNSPKSKKAKKKEEPSQNDISPKTKSLRKKKEPIEKKVVSSKTKK--VTKN 117
Query: 97 EAAMQSSNSESKKKKKKKRKMVNDAEPDTKKAKTENKGKSEEESAETTKETENNVEKPDN 156
E + K KK KK K +N E K K +N E ++ N
Sbjct: 118 EEPSEEEIDAPKPKKMKKEKEMN-GETREKSPKLKNGFPHPEPDCNPSEAASEE----SN 172
Query: 157 DEDESEVPSLPLGLTGAFEDTSFASLCNLVNENTLKAIKEMGFTNMTEIQHKSIRPLLEG 216
E E E+P GAF + ++E T+K +K G T + IQ K+ + G
Sbjct: 173 SEIEQEIPVEQK--EGAFSNFP-------ISEETIKLLKGRGVTFLFPIQAKTFHHVYSG 223
Query: 217 RDLLAAAKTGSGKTLAFLIPAVE-LIVKLRFMPRN-GTGVLILSPTRELAMQTFGVLKEL 274
+DL+A A+TG+GKT +F IP +E L +L+ R VL+L+PTRELA Q ++
Sbjct: 224 KDLIAQARTGTGKTFSFAIPLIEKLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDI 283
Query: 275 MTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVATPGRLLDHMQNTPGFMYKNLQCLVIDE 334
+ GG+ + +++ NGI+I+V TPGR+ DH+QN + K L+ +V+DE
Sbjct: 284 TKKL--SVACFYGGTPYGGQFERMRNGIDILVGTPGRIKDHIQNGKLDLTK-LKHVVLDE 340
Query: 335 ADRILDVGFEEELKQIIKLLPTRR-----QTMLFSATQTRKVEDLARISLKKEPLYVGVD 389
D++LD+GF +++++I+ + + QT+LFSAT V ++A+ +K V +
Sbjct: 341 VDQMLDMGFADQVEEILSVAYKKDSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLI 400
Query: 390 DDKANATVDGLEQGYVVCPSEKRFLLLFTFLK--KNRKKKLMVFFSSCMSVKYHYELL-- 445
K T +E + C +R ++ ++ + + ++F C + K EL
Sbjct: 401 GKKTQKTAITVEHLAIKCHWTQRAAVIGDVIRVYSGHQGRTIIF---CETKKEAQELSQN 457
Query: 446 NYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAARGLDIPEVDWIVQYDPPDD 505
+ I ++HG Q +R T F N G L+ T+VAARGLDIPEVD ++Q PP D
Sbjct: 458 SAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKD 517
Query: 506 PKEYIHRVGRTAR 518
+ YIHR GRT R
Sbjct: 518 VESYIHRSGRTGR 530
>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
[Homo sapiens]
Length = 406
Score = 184 bits (468), Expect = 2e-46
Identities = 125/339 (36%), Positives = 185/339 (54%), Gaps = 57/339 (16%)
Query: 186 VNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLR 245
V + +A ++G+T T+IQ ++I L+GRD++ A+TGSGKT AF +P + +++
Sbjct: 31 VTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFALPILNALLET- 89
Query: 246 FMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINII 305
P+ L+L+PTRELA Q + L + +I+GG + +++ L +II
Sbjct: 90 --PQR-LFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHII 146
Query: 306 VATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSA 365
+ATPGRL+DH++NT GF + L+ LV+DEADRIL++ FE E+ +I+K++P R+T LFSA
Sbjct: 147 IATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSA 206
Query: 366 TQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFLKKNRK 425
T T+KV+ L R +L K P+ V TV+ L+Q Y+ PS+ K R
Sbjct: 207 TMTKKVQKLQRAAL-KNPVKCAV--SSKYQTVEKLQQYYIFIPSK---------FKSKRL 254
Query: 426 KKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVA 485
L F + S+ LL TDVA
Sbjct: 255 GSLNKFKAKARSI----------------------------------------LLATDVA 274
Query: 486 ARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTAR-GLNGR 523
+RGLDIP VD +V +D P K+YIHRVGRTAR G +G+
Sbjct: 275 SRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGK 313
>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
[Homo sapiens]
Length = 881
Score = 184 bits (466), Expect = 3e-46
Identities = 147/449 (32%), Positives = 226/449 (50%), Gaps = 42/449 (9%)
Query: 192 KAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPRNG 251
K I + G+ T IQ K+I +L+G+D++A A+TGSGKT FL+P E + + G
Sbjct: 109 KGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKT--HSAQTG 166
Query: 252 TGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVATPGR 311
LILSPTRELA+QT KEL LI+GG + L +II+ATPGR
Sbjct: 167 ARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHENPDIIIATPGR 226
Query: 312 LLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSATQTRKV 371
L+ H+ ++++ +V DEADR+ ++GF E+L++II LP QT+LFSAT + +
Sbjct: 227 LV-HVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVLFSATLPKLL 285
Query: 372 EDLARISLKKEPLYVGVD-DDKANATVDGLEQGYVVCPSEKRFLLLFTFLKK--NRKKKL 428
+ AR L EP+ + +D D K N + L+ + + + + +L L + +
Sbjct: 286 VEFARAGLT-EPVLIRLDVDTKLN---EQLKTSFFLVREDTKAAVLLHLLHNVVRPQDQT 341
Query: 429 MVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAARG 488
+VF ++ +Y ELL + I+ R +F TL+ TD+AARG
Sbjct: 342 VVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTDLAARG 401
Query: 489 LDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGR-GHALLILRPEELGFL--------- 538
LDIP +D ++ Y P K ++HRVGR AR GR G A ++ P+E+ +L
Sbjct: 402 LDIPLLDNVINYSFPAKGKLFLHRVGRVARA--GRSGTAYSLVAPDEIPYLLDLHLFLGR 459
Query: 539 -----RYLKQ-----------SKVPLSEFDFSWSKISDIQSQLEKLIEKNYFLHKSAQEA 582
R LK+ +VP S D + S +QS LE +E L + A A
Sbjct: 460 SLTLARPLKEPSGVAGVDGMLGRVPQSVVD---EEDSGLQSTLEASLELR-GLARVADNA 515
Query: 583 YKSYIRAYDSHSLKQIFNVNNLNLPQVAL 611
+ Y+R+ + S + I ++L + L
Sbjct: 516 QQQYVRSRPAPSPESIKRAKEMDLVGLGL 544
>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
[Homo sapiens]
Length = 882
Score = 184 bits (466), Expect = 3e-46
Identities = 147/449 (32%), Positives = 226/449 (50%), Gaps = 42/449 (9%)
Query: 192 KAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPRNG 251
K I + G+ T IQ K+I +L+G+D++A A+TGSGKT FL+P E + + G
Sbjct: 109 KGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKT--HSAQTG 166
Query: 252 TGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVATPGR 311
LILSPTRELA+QT KEL LI+GG + L +II+ATPGR
Sbjct: 167 ARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHENPDIIIATPGR 226
Query: 312 LLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSATQTRKV 371
L+ H+ ++++ +V DEADR+ ++GF E+L++II LP QT+LFSAT + +
Sbjct: 227 LV-HVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVLFSATLPKLL 285
Query: 372 EDLARISLKKEPLYVGVD-DDKANATVDGLEQGYVVCPSEKRFLLLFTFLKK--NRKKKL 428
+ AR L EP+ + +D D K N + L+ + + + + +L L + +
Sbjct: 286 VEFARAGLT-EPVLIRLDVDTKLN---EQLKTSFFLVREDTKAAVLLHLLHNVVRPQDQT 341
Query: 429 MVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAARG 488
+VF ++ +Y ELL + I+ R +F TL+ TD+AARG
Sbjct: 342 VVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTDLAARG 401
Query: 489 LDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGR-GHALLILRPEELGFL--------- 538
LDIP +D ++ Y P K ++HRVGR AR GR G A ++ P+E+ +L
Sbjct: 402 LDIPLLDNVINYSFPAKGKLFLHRVGRVARA--GRSGTAYSLVAPDEIPYLLDLHLFLGR 459
Query: 539 -----RYLKQ-----------SKVPLSEFDFSWSKISDIQSQLEKLIEKNYFLHKSAQEA 582
R LK+ +VP S D + S +QS LE +E L + A A
Sbjct: 460 SLTLARPLKEPSGVAGVDGMLGRVPQSVVD---EEDSGLQSTLEASLELR-GLARVADNA 515
Query: 583 YKSYIRAYDSHSLKQIFNVNNLNLPQVAL 611
+ Y+R+ + S + I ++L + L
Sbjct: 516 QQQYVRSRPAPSPESIKRAKEMDLVGLGL 544
>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
sapiens]
Length = 648
Score = 183 bits (465), Expect = 4e-46
Identities = 134/418 (32%), Positives = 219/418 (52%), Gaps = 21/418 (5%)
Query: 106 ESKKKKKKKRKMVNDAEPDTKKAKTENKGKSEEESAETTKETENNVEKPDNDEDESEVPS 165
E K +K K + + + K T S+ E+ KE N D ++ +P+
Sbjct: 179 EGLKWQKTKWADLPPIKKNFYKESTATSAMSKVEADSWRKENFNITWDDLKDGEKRPIPN 238
Query: 166 LPLGLTGAFEDTSFASLCNLVNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKT 225
AF+ ++ IK+ GF T IQ ++ +L+G DL+ A+T
Sbjct: 239 PTCTFDDAFQ----------CYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQT 288
Query: 226 GSGKTLAFLIPA-VELIVKLRFM-PRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYG 283
G+GKTL +L+P + L+++ RN G+L+L+PTRELA+Q G + + +
Sbjct: 289 GTGKTLCYLMPGFIHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYSYKGLRSV- 347
Query: 284 LIMGGSNRSAEAQKLGNGINIIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGF 343
+ GG NR + ++L G++II+ATPGRL D +Q + KN+ LV+DEAD++LD+GF
Sbjct: 348 CVYGGGNRDEQIEELKKGVDIIIATPGRLND-LQMSNFVNLKNITYLVLDEADKMLDMGF 406
Query: 344 EEELKQIIKLLPTRRQTMLFSATQTRKVEDLARISLKKEPL--YVGVDDDKANATVDGLE 401
E ++ +I+ + RQT++ SAT V LA+ S KEP+ YVG D A V ++
Sbjct: 407 EPQIMKILLDVRPDRQTVMTSATWPHSVHRLAQ-SYLKEPMIVYVGTLDLVA---VSSVK 462
Query: 402 QGYVVCPSEKRFLLLFTFLKKNRKKKLMVFFSSCMSVKYHYEL-LNYIDLPVLAIHGKQK 460
Q +V E+++ + TFL+ ++ F S +V H L ++ V ++HG ++
Sbjct: 463 QNIIVTTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDRE 522
Query: 461 QNKRTTTFFQFCNADSGTLLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTAR 518
Q R F L+ TD+A+RGLD+ +V + +D P + +EY+HR+GRT R
Sbjct: 523 QRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGR 580
>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
Length = 622
Score = 181 bits (460), Expect = 1e-45
Identities = 114/341 (33%), Positives = 190/341 (55%), Gaps = 15/341 (4%)
Query: 191 LKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIV----KLRF 246
L+ +K+ G + T IQ + I +L GRD++ A TGSGKTL F +P + + +L F
Sbjct: 193 LRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPF 252
Query: 247 MPRNGTGVLILSPTRELAMQTFGVLKELM------THHVHTYGLIMGGSNRSAEAQKLGN 300
R G LI+ P+RELA QT G+L+ + + L +GG + + + + +
Sbjct: 253 SKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRH 312
Query: 301 GINIIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQT 360
G++++VATPGRL+D +Q + + L +DEADR++D+GFE +++ I +RQT
Sbjct: 313 GVHMMVATPGRLMDLLQKKMVSL-DICRYLALDEADRMIDMGFEGDIRTIFSYFKGQRQT 371
Query: 361 MLFSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFL 420
+LFSAT +K+++ A+ +L K P+ + V A A++D +++ V E + + L L
Sbjct: 372 LLFSATMPKKIQNFAKSALVK-PVTINVGRAGA-ASLDVIQEVEYV-KEEAKMVYLLECL 428
Query: 421 KKNRKKKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLL 480
+K +++F V +E L + +AIHG + Q +RT F L+
Sbjct: 429 QKT-PPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLV 487
Query: 481 CTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLN 521
TDVA++GLD P + ++ YD P++ + Y+HR+GRT R N
Sbjct: 488 ATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGN 528
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 180 bits (456), Expect = 4e-45
Identities = 129/400 (32%), Positives = 209/400 (52%), Gaps = 21/400 (5%)
Query: 186 VNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLR 245
++ L ++K+ G+ T IQ ++I ++ GRDL+ AKTGSGKT+AFL+P I+ R
Sbjct: 379 ISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQR 438
Query: 246 FMPRN-GTGVLILSPTRELAMQTFGVLKELMTHHVHTYGL----IMGGSNRSAEAQKLGN 300
+ G +I++PTRELA+Q K+ T GL + GG+ S + +L
Sbjct: 439 SLEEGEGPIAVIMTPTRELALQITKECKKFSK----TLGLRVVCVYGGTGISEQIAELKR 494
Query: 301 GINIIVATPGRLLDHMQNTPGFM--YKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRR 358
G IIV TPGR++D + G + + + +V+DEADR+ D+GFE ++ +I+ + R
Sbjct: 495 GAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDR 554
Query: 359 QTMLFSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFT 418
QT++FSAT R +E LAR L K P+ V V + +EQ +V EK+FL L
Sbjct: 555 QTVMFSATFPRAMEALARRILSK-PIEVQVGG--RSVVCSDVEQQVIVIEEEKKFLKLLE 611
Query: 419 FLKKNRKK-KLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSG 477
L ++ +++F + L P +++HG Q R + F N
Sbjct: 612 LLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCK 671
Query: 478 TLLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGF 537
L+ T VAARGLD+ + +V Y P+ ++Y+HR GRT R N +G+A + ++ +
Sbjct: 672 LLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGN-KGYAYTFITEDQARY 730
Query: 538 ----LRYLKQSKVPL-SEFDFSWSKISDIQSQLEKLIEKN 572
++ L+ S + + + WS D Q K+I+K+
Sbjct: 731 AGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKS 770
Score = 37.7 bits (86), Expect = 0.035
Identities = 33/151 (21%), Positives = 66/151 (43%), Gaps = 6/151 (3%)
Query: 10 RKKIEKRNLKLRQRNLKFQGASNLTLSETQNGDVSEETMGSRKVKKSKQKPMNVGLSETQ 69
RK++ + + R R+ + + + + +++ + S KSK+ E
Sbjct: 65 RKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKT 124
Query: 70 NGGMSQEAVGNIKVTKSPQKSTVLTNGEAAMQSSNSESKKKKKKKRKMVNDAEPDTKKAK 129
+GG S + K K +K +A N ++ +K+K ++ E KKA
Sbjct: 125 DGGESSKEKKKDKDDKEDEKEK-----DAGNFDQNKLEEEMRKRKERVEKWREEQRKKAM 179
Query: 130 TENKGKSEEESAETTKETENNVEKPDNDEDE 160
EN G+ ++E E + + ++E D+DED+
Sbjct: 180 -ENIGELKKEIEEMKQGKKWSLEDDDDDEDD 209
Score = 33.1 bits (74), Expect = 0.85
Identities = 17/66 (25%), Positives = 30/66 (45%), Gaps = 1/66 (1%)
Query: 97 EAAMQSSNSESKKKKKKKRKMVNDAEPDTKKAKTENKGKSEEESAETTKETENNVEKPDN 156
E S + + + + + + P K KTEN+ +S+E++ E +K D+
Sbjct: 81 ERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDK-DD 139
Query: 157 DEDESE 162
EDE E
Sbjct: 140 KEDEKE 145
>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
Length = 731
Score = 178 bits (451), Expect = 2e-44
Identities = 115/354 (32%), Positives = 193/354 (54%), Gaps = 6/354 (1%)
Query: 191 LKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPR- 249
+ + + FT T IQ + L GRD++ A+TGSGKTLA+L+PA+ I ++ R
Sbjct: 183 MDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERG 242
Query: 250 NGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVATP 309
+G L+L+PTRELA Q V + I GG+ + + + L G+ I +ATP
Sbjct: 243 DGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATP 302
Query: 310 GRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSATQTR 369
GRL+D +++ + + LV+DEADR+LD+GFE ++++I+ + RQT+++SAT +
Sbjct: 303 GRLIDFLESGKTNL-RRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPK 361
Query: 370 KVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEK--RFLLLFTFLKKNRKKK 427
+V LA L+ + + V + + +A + L+ V SEK + + L + ++ K
Sbjct: 362 EVRQLAEDFLR-DYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENK 420
Query: 428 LMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAAR 487
++F + + P + IHG + Q +R +F + + L+ TDVA+R
Sbjct: 421 TIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASR 480
Query: 488 GLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLRYL 541
GLD+ +V +++ YD P+ ++Y+HR+GRTAR N +G A P L R L
Sbjct: 481 GLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTN-KGTAYTFFTPGNLKQAREL 533
>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
Length = 729
Score = 178 bits (451), Expect = 2e-44
Identities = 115/354 (32%), Positives = 193/354 (54%), Gaps = 6/354 (1%)
Query: 191 LKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPR- 249
+ + + FT T IQ + L GRD++ A+TGSGKTLA+L+PA+ I ++ R
Sbjct: 183 MDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERG 242
Query: 250 NGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVATP 309
+G L+L+PTRELA Q V + I GG+ + + + L G+ I +ATP
Sbjct: 243 DGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATP 302
Query: 310 GRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSATQTR 369
GRL+D +++ + + LV+DEADR+LD+GFE ++++I+ + RQT+++SAT +
Sbjct: 303 GRLIDFLESGKTNL-RRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPK 361
Query: 370 KVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEK--RFLLLFTFLKKNRKKK 427
+V LA L+ + + V + + +A + L+ V SEK + + L + ++ K
Sbjct: 362 EVRQLAEDFLR-DYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENK 420
Query: 428 LMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAAR 487
++F + + P + IHG + Q +R +F + + L+ TDVA+R
Sbjct: 421 TIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASR 480
Query: 488 GLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLRYL 541
GLD+ +V +++ YD P+ ++Y+HR+GRTAR N +G A P L R L
Sbjct: 481 GLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTN-KGTAYTFFTPGNLKQAREL 533
>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
Length = 614
Score = 176 bits (446), Expect = 6e-44
Identities = 109/332 (32%), Positives = 179/332 (53%), Gaps = 3/332 (0%)
Query: 189 NTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMP 248
N + I FT T IQ + L G D++ A+TGSGKTL++L+PA+ I F+
Sbjct: 104 NVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLE 163
Query: 249 R-NGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVA 307
R +G L+L+PTRELA Q V E I GG+ + + + L G+ I +A
Sbjct: 164 RGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIA 223
Query: 308 TPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSATQ 367
TPGRL+D ++ + + LV+DEADR+LD+GFE ++++I+ + RQT+++SAT
Sbjct: 224 TPGRLIDFLECGKTNLRRTTY-LVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATW 282
Query: 368 TRKVEDLARISLKKE-PLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFLKKNRKK 426
++V LA LK + +G + AN + + +++ + L + ++
Sbjct: 283 PKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKEN 342
Query: 427 KLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAA 486
K +VF + + P + IHG + Q +R +F + + L+ TDVA+
Sbjct: 343 KTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVAS 402
Query: 487 RGLDIPEVDWIVQYDPPDDPKEYIHRVGRTAR 518
RGLD+ +V +++ YD P+ ++YIHR+GRTAR
Sbjct: 403 RGLDVEDVKFVINYDYPNSSEDYIHRIGRTAR 434
>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
[Homo sapiens]
Length = 690
Score = 174 bits (441), Expect = 2e-43
Identities = 142/491 (28%), Positives = 226/491 (46%), Gaps = 42/491 (8%)
Query: 68 TQNGGMSQEAVGNIKVTKSPQKSTVLTNGEAAMQSSN-----SESKKKKKKKRKMVNDAE 122
T+N G S+ ++ + Q++ L + S S+S+ +R
Sbjct: 122 TRNRGFSKRGDNDLDPDECMQRTGGLFGSRRPVLSGTGNGDTSQSRSGSGSERGGYKGLN 181
Query: 123 PDTKKAKTENKGKSEEE---SAETTKETENNVEKPDNDEDESEVPSLPLGLTGAFEDTSF 179
+ +N KSE E S++T + P ++++S G+ DT
Sbjct: 182 EEVITGSGKNSWKSEAEGGESSDTQGPKVTYIPPPPPEDEDSIFAHYQTGINFDKYDTIL 241
Query: 180 -----------------ASLCNLVNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAA 222
A+LC +N N KA G+T +T +Q SI +L GRDL+A
Sbjct: 242 VEVSGHDAPPAILTFEEANLCQTLNNNIAKA----GYTKLTPVQKYSIPIILAGRDLMAC 297
Query: 223 AKTGSGKTLAFLIPAV-----ELIVKLRFMPRNGTGVLILSPTRELAMQTFGVLKELMTH 277
A+TGSGKT AFL+P + + I RF +I++PTREL Q + ++
Sbjct: 298 AQTGSGKTAAFLLPILAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFG 357
Query: 278 HVHTYGLIMGGSNRSAEAQKLGNGINIIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADR 337
+I GG+ +++ G NI+ ATPGRL+D + K ++ LV+DEADR
Sbjct: 358 TCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGRLMDIIGKEK-IGLKQIKYLVLDEADR 416
Query: 338 ILDVGFEEELKQIIKL--LPTR--RQTMLFSATQTRKVEDLARISLKKEPLYVGVDDDKA 393
+LD+GF E+K++I +P++ RQT++FSAT +++ LA LK L+V V +
Sbjct: 417 MLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNYLFVAVG--QV 474
Query: 394 NATVDGLEQGYVVCPSEKRFLLLFTFLKKNRKKKLMVFFSSCMSVKYHYELLNYIDLPVL 453
++Q + + L L+ ++ MVF + + L +
Sbjct: 475 GGACRDVQQTVLQVGQFSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEKISTT 534
Query: 454 AIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRV 513
+IHG ++Q +R F L+ T VAARGLDI V ++ +D P EY+HR+
Sbjct: 535 SIHGDREQREREQALGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRI 594
Query: 514 GRTAR-GLNGR 523
GRT R G GR
Sbjct: 595 GRTGRCGNTGR 605
>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
[Homo sapiens]
Length = 724
Score = 174 bits (440), Expect = 3e-43
Identities = 139/457 (30%), Positives = 217/457 (47%), Gaps = 39/457 (8%)
Query: 95 NGEAAMQSSNSESKKKKKKKRKMVNDAEPDTKKAKTENKGKSEE-ESAETTKETENNVEK 153
NG+ + S S S++ K + E T K K ++E ES++T +
Sbjct: 194 NGDTSQSRSGSGSERGGYKGL----NEEVITGSGKNSWKSEAEGGESSDTQGPKVTYIPP 249
Query: 154 PDNDEDESEVPSLPLGLTGAFEDTSF-----------------ASLCNLVNENTLKAIKE 196
P ++++S G+ DT A+LC +N N KA
Sbjct: 250 PPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKA--- 306
Query: 197 MGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAV-----ELIVKLRFMPRNG 251
G+T +T +Q SI +L GRDL+A A+TGSGKT AFL+P + + I RF
Sbjct: 307 -GYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQE 365
Query: 252 TGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVATPGR 311
+I++PTREL Q + ++ +I GG+ +++ G NI+ ATPGR
Sbjct: 366 PECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGR 425
Query: 312 LLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKL--LPTR--RQTMLFSATQ 367
L+D + K ++ LV+DEADR+LD+GF E+K++I +P++ RQT++FSAT
Sbjct: 426 LMDIIGKEK-IGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATF 484
Query: 368 TRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFLKKNRKKK 427
+++ LA LK L+V V + ++Q + + L L+ ++
Sbjct: 485 PEEIQRLAAEFLKSNYLFVAVG--QVGGACRDVQQTVLQVGQFSKREKLVEILRNIGDER 542
Query: 428 LMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAAR 487
MVF + + L + +IHG ++Q +R F L+ T VAAR
Sbjct: 543 TMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAAR 602
Query: 488 GLDIPEVDWIVQYDPPDDPKEYIHRVGRTAR-GLNGR 523
GLDI V ++ +D P EY+HR+GRT R G GR
Sbjct: 603 GLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGR 639
>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
[Homo sapiens]
Length = 724
Score = 174 bits (440), Expect = 3e-43
Identities = 139/457 (30%), Positives = 217/457 (47%), Gaps = 39/457 (8%)
Query: 95 NGEAAMQSSNSESKKKKKKKRKMVNDAEPDTKKAKTENKGKSEE-ESAETTKETENNVEK 153
NG+ + S S S++ K + E T K K ++E ES++T +
Sbjct: 194 NGDTSQSRSGSGSERGGYKGL----NEEVITGSGKNSWKSEAEGGESSDTQGPKVTYIPP 249
Query: 154 PDNDEDESEVPSLPLGLTGAFEDTSF-----------------ASLCNLVNENTLKAIKE 196
P ++++S G+ DT A+LC +N N KA
Sbjct: 250 PPPEDEDSIFAHYQTGINFDKYDTILVEVSGHDAPPAILTFEEANLCQTLNNNIAKA--- 306
Query: 197 MGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAV-----ELIVKLRFMPRNG 251
G+T +T +Q SI +L GRDL+A A+TGSGKT AFL+P + + I RF
Sbjct: 307 -GYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPILAHMMHDGITASRFKELQE 365
Query: 252 TGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVATPGR 311
+I++PTREL Q + ++ +I GG+ +++ G NI+ ATPGR
Sbjct: 366 PECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGHSIRQIVQGCNILCATPGR 425
Query: 312 LLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKL--LPTR--RQTMLFSATQ 367
L+D + K ++ LV+DEADR+LD+GF E+K++I +P++ RQT++FSAT
Sbjct: 426 LMDIIGKEK-IGLKQIKYLVLDEADRMLDMGFGPEMKKLISCPGMPSKEQRQTLMFSATF 484
Query: 368 TRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFLKKNRKKK 427
+++ LA LK L+V V + ++Q + + L L+ ++
Sbjct: 485 PEEIQRLAAEFLKSNYLFVAVG--QVGGACRDVQQTVLQVGQFSKREKLVEILRNIGDER 542
Query: 428 LMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAAR 487
MVF + + L + +IHG ++Q +R F L+ T VAAR
Sbjct: 543 TMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQALGDFRFGKCPVLVATSVAAR 602
Query: 488 GLDIPEVDWIVQYDPPDDPKEYIHRVGRTAR-GLNGR 523
GLDI V ++ +D P EY+HR+GRT R G GR
Sbjct: 603 GLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGR 639
>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
sapiens]
Length = 599
Score = 172 bits (435), Expect = 1e-42
Identities = 149/503 (29%), Positives = 243/503 (48%), Gaps = 39/503 (7%)
Query: 95 NGEAAMQSSNSESKKKKKKKRKMVNDAEPDTKK-----------AKTENKGKSEEESAET 143
NGE +S +++ KKKRK + ++ AK E+K K + ES T
Sbjct: 70 NGEKKEESLTERKREQSKKKRKTMTSEIASQEEGATIQWMSSVEAKIEDK-KVQRESKLT 128
Query: 144 TKETEN-NVEKPDNDEDESEVPSLPLGLTGAFEDTSFASLCNLVNENTLKAIKEMGFTNM 202
+ + EN EK + ++ ++ L +N L+ I + GF
Sbjct: 129 SGKLENLRKEKINFLRNKHKIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMP 188
Query: 203 TEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPRNGTGVLILSPTRE 262
T IQ ++I +L GR+LLA+A TGSGKTLAF IP ++++L+ G LI+SPTRE
Sbjct: 189 TPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIP---ILMQLKQPANKGFRALIISPTRE 245
Query: 263 LAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLG----NGINIIVATPGRLLDHM-Q 317
LA Q + +EL+ T I + A+K G +I+V TP RL+ + Q
Sbjct: 246 LASQ---IHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQ 302
Query: 318 NTPGFMYKNLQCLVIDEADRILD---VGFEEELKQIIKLLPTRR-QTMLFSATQTRKVED 373
+ PG +++ LV+DE+D++ + GF ++L I + + + +FSAT VE
Sbjct: 303 DPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQ 362
Query: 374 LARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEK-RFLLLFTFLKKNRKKKLMVFF 432
+++L + V N+ V+ +EQ + SE + L + +KK ++VF
Sbjct: 363 WCKLNLDN---VISVSIGARNSAVETVEQELLFVGSETGKLLAMRELVKKGFNPPVLVFV 419
Query: 433 SSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAARGLDIP 492
S K + L Y + V IH ++ Q +R T F L+CT + ARG+D
Sbjct: 420 QSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFK 479
Query: 493 EVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLR----YLKQSKVPL 548
V+ ++ YD P EYIHR+GRT R N +G A+ ++ LR ++Q+ P+
Sbjct: 480 GVNLVINYDFPTSSVEYIHRIGRTGRAGN-KGKAITFFTEDDKPLLRSVANVIQQAGCPV 538
Query: 549 SEFDFSWSKISDIQSQLEKLIEK 571
E+ + K+ + Q +K+I+K
Sbjct: 539 PEYIKGFQKL--LSKQKKKMIKK 559
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 167 bits (424), Expect = 2e-41
Identities = 117/340 (34%), Positives = 183/340 (53%), Gaps = 25/340 (7%)
Query: 199 FTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVK------LRFMPRNGT 252
+T T +Q +I + E RDL+A A+TGSGKT AFL+P + I LR M NG
Sbjct: 200 YTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGR 259
Query: 253 G--------VLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINI 304
L+L+PTRELA+Q + ++ ++ GG++ + + L G ++
Sbjct: 260 YGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHL 319
Query: 305 IVATPGRLLDHMQNTP-GFMYKNLQCLVIDEADRILDVGFEEELKQIIK--LLPTR--RQ 359
+VATPGRL+D M+ G + + LV+DEADR+LD+GFE ++++I++ +P + R
Sbjct: 320 LVATPGRLVDMMERGKIGLDF--CKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRH 377
Query: 360 TMLFSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYV-VCPSEKRFLLLFT 418
TM+FSAT ++++ LAR L + Y+ + + +T + + Q V V S+KR LL
Sbjct: 378 TMMFSATFPKEIQMLARDFLDE---YIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDL 434
Query: 419 FLKKNRKKKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGT 478
+ +VF + + L + +IHG + Q R QF + S
Sbjct: 435 LNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPI 494
Query: 479 LLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTAR 518
L+ T VAARGLDI V ++ +D P D +EY+HR+GRT R
Sbjct: 495 LVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGR 534
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 167 bits (423), Expect = 3e-41
Identities = 107/360 (29%), Positives = 201/360 (55%), Gaps = 12/360 (3%)
Query: 186 VNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELI-VKL 244
+ E+ L+ I GF + IQ ++I+ +++GRD++A +++G+GKT F I ++ + +++
Sbjct: 45 LREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQV 104
Query: 245 RFMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINI 304
R T LIL+PTRELA+Q L L + +GG+N + +KL G ++
Sbjct: 105 R-----ETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHV 159
Query: 305 IVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFS 364
+ TPGR+ D ++ + ++ LV+DEAD +L+ GF+E++ + + LP Q +L S
Sbjct: 160 VAGTPGRVFDMIRRR-SLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLIS 218
Query: 365 ATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEK-RFLLLFTFLKKN 423
AT ++ ++ +P+ + V D+ T++G++Q +V E+ +F L
Sbjct: 219 ATLPHEILEMTN-KFMTDPIRILVKRDEL--TLEGIKQFFVAVEREEWKFDTLCDLYDTL 275
Query: 424 RKKKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTD 483
+ ++F ++ V + E + + V ++HG Q +R + +F + S L+ TD
Sbjct: 276 TITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTD 335
Query: 484 VAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLRYLKQ 543
V ARGLD+P+V I+ YD P++ + YIHR+GR+ R +G A+ ++ +++ LR ++Q
Sbjct: 336 VWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGR-YGRKGVAINFVKNDDIRILRDIEQ 394
>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 166 bits (421), Expect = 5e-41
Identities = 113/352 (32%), Positives = 178/352 (50%), Gaps = 4/352 (1%)
Query: 187 NENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPA-VELIVKLR 245
+E + I++ +T T IQ + + L GRD++ AKTGSGKT AF+ P + ++ +
Sbjct: 261 DEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKE 320
Query: 246 FMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINII 305
P +G +I+ PTREL Q K + + GG + +A+ L G I+
Sbjct: 321 LEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIV 380
Query: 306 VATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSA 365
V TPGRL+DH++ + + + LV DEADR+ D+GFE +++ I + RQT+LFSA
Sbjct: 381 VCTPGRLIDHVKKKATNLQR-VSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSA 439
Query: 366 TQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFLKKNRK 425
T +K+E LAR L V D +AN V + + PS+ +L ++
Sbjct: 440 TFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTR-RLVEFTSS 498
Query: 426 KKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVA 485
+++F + + + L + +HG Q++R F D L+ TDVA
Sbjct: 499 GSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVA 558
Query: 486 ARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGF 537
ARGLDIP + ++ YD D + HR+GRT R +G A +L P++ F
Sbjct: 559 ARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRA-GEKGVAYTLLTPKDSNF 609
>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 166 bits (421), Expect = 5e-41
Identities = 113/352 (32%), Positives = 178/352 (50%), Gaps = 4/352 (1%)
Query: 187 NENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPA-VELIVKLR 245
+E + I++ +T T IQ + + L GRD++ AKTGSGKT AF+ P + ++ +
Sbjct: 261 DEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKE 320
Query: 246 FMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINII 305
P +G +I+ PTREL Q K + + GG + +A+ L G I+
Sbjct: 321 LEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIV 380
Query: 306 VATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSA 365
V TPGRL+DH++ + + + LV DEADR+ D+GFE +++ I + RQT+LFSA
Sbjct: 381 VCTPGRLIDHVKKKATNLQR-VSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSA 439
Query: 366 TQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFLKKNRK 425
T +K+E LAR L V D +AN V + + PS+ +L ++
Sbjct: 440 TFRKKIEKLARDILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTR-RLVEFTSS 498
Query: 426 KKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVA 485
+++F + + + L + +HG Q++R F D L+ TDVA
Sbjct: 499 GSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVA 558
Query: 486 ARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGF 537
ARGLDIP + ++ YD D + HR+GRT R +G A +L P++ F
Sbjct: 559 ARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRA-GEKGVAYTLLTPKDSNF 609
>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
[Homo sapiens]
Length = 406
Score = 165 bits (418), Expect = 1e-40
Identities = 119/398 (29%), Positives = 206/398 (51%), Gaps = 18/398 (4%)
Query: 144 TKETENNVEKPDNDEDESEVPSLPLGLTGAFEDTSFASLCNLVNENTLKAIKEMGFTNMT 203
++++ + PD E E + S + +F+D + ++E+ L+ I GF +
Sbjct: 4 SQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMN-------LSESLLRGIYAYGFEKPS 56
Query: 204 EIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPRNGTGVLILSPTREL 263
IQ ++I P ++G D++A A++G+GKT F I ++ I + T L+L+PTREL
Sbjct: 57 AIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIE----LDLKATQALVLAPTREL 112
Query: 264 AMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLG-NGINIIVATPGRLLDHMQNTPGF 322
A Q V+ L + + +GG+N AE QKL +IIV TPGR+ D M N
Sbjct: 113 AQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFD-MLNRRYL 171
Query: 323 MYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSATQTRKVEDLARISLKKE 382
K ++ V+DEAD +L GF++++ I + L + Q +L SAT V ++ + ++
Sbjct: 172 SPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTK-KFMRD 230
Query: 383 PLYVGVDDDKANATVDGLEQGYVVCPSEKRFL-LLFTFLKKNRKKKLMVFFSSCMSVKYH 441
P+ + V K T++G+ Q Y+ E+ L L + + ++F ++ V +
Sbjct: 231 PIRILVK--KEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWL 288
Query: 442 YELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCTDVAARGLDIPEVDWIVQYD 501
E ++ D V A+HG Q +R +F + S L+ TD+ ARG+D+ +V ++ YD
Sbjct: 289 TEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYD 348
Query: 502 PPDDPKEYIHRVGRTARGLNGRGHALLILRPEELGFLR 539
P + + YIHR+GR R +G A+ ++ E+ LR
Sbjct: 349 LPTNRENYIHRIGRGGR-FGRKGVAINMVTEEDKRTLR 385
>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
sapiens]
Length = 491
Score = 165 bits (418), Expect = 1e-40
Identities = 127/400 (31%), Positives = 205/400 (51%), Gaps = 26/400 (6%)
Query: 186 VNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLR 245
+N L+ I + GF T IQ ++I +L GR+LLA+A TGSGKTLAF IP ++++L+
Sbjct: 64 INSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIP---ILMQLK 120
Query: 246 FMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLG----NG 301
G LI+SPTRELA Q + +EL+ T I + A+K G
Sbjct: 121 QPANKGFRALIISPTRELASQ---IHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKK 177
Query: 302 INIIVATPGRLLDHM-QNTPGFMYKNLQCLVIDEADRILD---VGFEEELKQIIKLLPTR 357
+I+V TP RL+ + Q+ PG +++ LV+DE+D++ + GF ++L I +
Sbjct: 178 FDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTSH 237
Query: 358 R-QTMLFSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEK-RFLL 415
+ + +FSAT VE +++L + V N+ V+ +EQ + SE + L
Sbjct: 238 KVRRAMFSATFAYDVEQWCKLNLDN---VISVSIGARNSAVETVEQELLFVGSETGKLLA 294
Query: 416 LFTFLKKNRKKKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNAD 475
+ +KK ++VF S K + L Y + V IH ++ Q +R T F
Sbjct: 295 MRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGK 354
Query: 476 SGTLLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEEL 535
L+CT + ARG+D V+ ++ YD P EYIHR+GRT R N +G A+ ++
Sbjct: 355 IWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGN-KGKAITFFTEDDK 413
Query: 536 GFLR----YLKQSKVPLSEFDFSWSKISDIQSQLEKLIEK 571
LR ++Q+ P+ E+ + K+ + Q +K+I+K
Sbjct: 414 PLLRSVANVIQQAGCPVPEYIKGFQKL--LSKQKKKMIKK 451
>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
sapiens]
Length = 483
Score = 162 bits (411), Expect = 7e-40
Identities = 111/398 (27%), Positives = 201/398 (50%), Gaps = 21/398 (5%)
Query: 126 KKAKTENKGKSEEESAETTKETENNVEKPDNDEDESEVPSLPLGL----TGAFEDTSFAS 181
K T N G ++ + TT ++ D+ + ++P L + + + F
Sbjct: 46 KNTNTINNGTQQQAQSMTT-----TIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFED 100
Query: 182 LCNLVNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELI 241
C + L I EMG+ + IQ +SI L GRD+LA AK G+GK+ A+LIP +E +
Sbjct: 101 YC--LKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERL 158
Query: 242 VKLRFMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIM-GGSNRSAEAQKLGN 300
+ ++ +++ PTRELA+Q + ++ H + GG+N + +L +
Sbjct: 159 D----LKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDD 214
Query: 301 GINIIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQT 360
+++++ATPGR+LD ++ + ++Q +V+DEAD++L F + ++ II LP RQ
Sbjct: 215 TVHVVIATPGRILDLIKKGVAKV-DHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQI 273
Query: 361 MLFSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFL 420
+L+SAT V+ L+K P + + ++ T+ G+ Q Y ++ L T
Sbjct: 274 LLYSATFPLSVQKFMNSHLQK-PYEINLMEE---LTLKGVTQYYAYVTERQKVHCLNTLF 329
Query: 421 KKNRKKKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLL 480
+ + + ++F +S V+ + ++ + IH K +Q R F F N L+
Sbjct: 330 SRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLV 389
Query: 481 CTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTAR 518
CTD+ RG+DI V+ ++ +D P + Y+HR+GR+ R
Sbjct: 390 CTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGR 427
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,386,313
Number of Sequences: 37866
Number of extensions: 1114088
Number of successful extensions: 8892
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 250
Number of HSP's successfully gapped in prelim test: 311
Number of HSP's that attempted gapping in prelim test: 5793
Number of HSP's gapped (non-prelim): 2055
length of query: 670
length of database: 18,247,518
effective HSP length: 109
effective length of query: 561
effective length of database: 14,120,124
effective search space: 7921389564
effective search space used: 7921389564
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.