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Search of human proteins with 38327535
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38327535 insulin-like 3 precursor [Homo sapiens]
(131 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38327535 insulin-like 3 precursor [Homo sapiens] 285 9e-78
gi|38569233 insulin-like 5 precursor [Homo sapiens] 39 0.001
gi|18254464 relaxin 3 preproprotein [Homo sapiens] 34 0.037
gi|4557671 proinsulin precursor [Homo sapiens] 32 0.11
gi|38569396 insulin-like 6 precursor [Homo sapiens] 32 0.14
gi|109148522 insulin- insulin-like growth factor 2 [Homo sapiens] 31 0.24
gi|20143933 relaxin 2 isoform 1 preproprotein [Homo sapiens] 31 0.32
gi|5902052 relaxin 1 preproprotein [Homo sapiens] 30 0.70
gi|20143935 relaxin 2 isoform 2 [Homo sapiens] 30 0.70
gi|118600967 shroom family member 4 [Homo sapiens] 29 1.2
gi|13376253 ribonuclease P 21 [Homo sapiens] 28 2.1
gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens] 28 2.1
gi|54607124 RNA binding motif protein 15B [Homo sapiens] 28 2.1
gi|91208437 GEM interacting protein [Homo sapiens] 28 2.1
gi|10092665 sushi domain containing 2 [Homo sapiens] 28 2.7
gi|148233912 C1q and tumor necrosis factor related protein 4 [Ho... 27 3.5
gi|11967991 SRY-box 17 [Homo sapiens] 27 4.6
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens] 27 4.6
gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap... 27 4.6
gi|223633890 hypothetical protein LOC729956 [Homo sapiens] 27 6.0
gi|239752128 PREDICTED: hypothetical protein [Homo sapiens] 27 6.0
gi|122937233 discs, large (Drosophila) homolog-associated protei... 27 6.0
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 27 6.0
gi|42476101 TFIIA alpha, p55 isoform 2 [Homo sapiens] 27 6.0
gi|7706735 TFIIA alpha, p55 isoform 1 [Homo sapiens] 27 6.0
gi|21361411 HMG-box transcription factor 1 [Homo sapiens] 27 6.0
gi|169162130 PREDICTED: tetratricopeptide repeat domain 34 [Homo... 26 7.8
gi|145580586 kintoun isoform 2 [Homo sapiens] 26 7.8
gi|145580588 kintoun isoform 1 [Homo sapiens] 26 7.8
gi|5032115 sprouty 2 [Homo sapiens] 26 7.8
>gi|38327535 insulin-like 3 precursor [Homo sapiens]
Length = 131
Score = 285 bits (728), Expect = 9e-78
Identities = 131/131 (100%), Positives = 131/131 (100%)
Query: 1 MDPRLPAWALVLLGPALVFALGPAPTPEMREKLCGHHFVRALVRVCGGPRWSTEARRPAT 60
MDPRLPAWALVLLGPALVFALGPAPTPEMREKLCGHHFVRALVRVCGGPRWSTEARRPAT
Sbjct: 1 MDPRLPAWALVLLGPALVFALGPAPTPEMREKLCGHHFVRALVRVCGGPRWSTEARRPAT 60
Query: 61 GGDRELLQWLERRHLLHGLVADSNLTLGPGLQPLPQTSHHHRHHRAAATNPARYCCLSGC 120
GGDRELLQWLERRHLLHGLVADSNLTLGPGLQPLPQTSHHHRHHRAAATNPARYCCLSGC
Sbjct: 61 GGDRELLQWLERRHLLHGLVADSNLTLGPGLQPLPQTSHHHRHHRAAATNPARYCCLSGC 120
Query: 121 TQQDLLTLCPY 131
TQQDLLTLCPY
Sbjct: 121 TQQDLLTLCPY 131
>gi|38569233 insulin-like 5 precursor [Homo sapiens]
Length = 135
Score = 38.9 bits (89), Expect = 0.001
Identities = 29/125 (23%), Positives = 50/125 (40%), Gaps = 12/125 (9%)
Query: 16 ALVFALGPAPTPEMREKLCGHHFVRALVRVCGGPRWS------TEARRPATGGDRELLQW 69
+++FA+ + E +LCG ++R ++ +C RW +A++ TG +L
Sbjct: 12 SVLFAISEVRSKES-VRLCGLEYIRTVIYICASSRWRRHQEGIPQAQQAETGNSFQLPHK 70
Query: 70 LE-----RRHLLHGLVADSNLTLGPGLQPLPQTSHHHRHHRAAATNPARYCCLSGCTQQD 124
E L + A L G P + +H + + CC GC+ D
Sbjct: 71 REFSEENPAQNLPKVDASGEDRLWGGQMPTEELWKSKKHSVMSRQDLQTLCCTDGCSMTD 130
Query: 125 LLTLC 129
L LC
Sbjct: 131 LSALC 135
>gi|18254464 relaxin 3 preproprotein [Homo sapiens]
Length = 142
Score = 33.9 bits (76), Expect = 0.037
Identities = 11/20 (55%), Positives = 15/20 (75%)
Query: 32 KLCGHHFVRALVRVCGGPRW 51
+LCG F+RA++ CGG RW
Sbjct: 33 RLCGREFIRAVIFTCGGSRW 52
>gi|4557671 proinsulin precursor [Homo sapiens]
Length = 110
Score = 32.3 bits (72), Expect = 0.11
Identities = 39/128 (30%), Positives = 48/128 (37%), Gaps = 28/128 (21%)
Query: 8 WALVLLGPALVFALGPAPTPE-MREKLCGHHFVRALVRVCG--GPRWSTEARRPATGGDR 64
W +L AL+ GP P + + LCG H V AL VCG G ++ + RR A
Sbjct: 4 WMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREA----- 58
Query: 65 ELLQWLERRHLLHGLVADSNLTLGPG---LQPLPQTSHHHRHHRAAATNPARYCCLSGCT 121
E LQ V L GPG LQPL + CC S C+
Sbjct: 59 EDLQ-----------VGQVELGGGPGAGSLQPLALEGSLQKR------GIVEQCCTSICS 101
Query: 122 QQDLLTLC 129
L C
Sbjct: 102 LYQLENYC 109
>gi|38569396 insulin-like 6 precursor [Homo sapiens]
Length = 213
Score = 32.0 bits (71), Expect = 0.14
Identities = 17/50 (34%), Positives = 24/50 (48%)
Query: 3 PRLPAWALVLLGPALVFALGPAPTPEMREKLCGHHFVRALVRVCGGPRWS 52
PRL +L+ LG LV KLCG + V+ + ++CG WS
Sbjct: 2 PRLLRLSLLWLGLLLVRFSRELSDISSARKLCGRYLVKEIEKLCGHANWS 51
Score = 28.1 bits (61), Expect = 2.1
Identities = 13/34 (38%), Positives = 19/34 (55%), Gaps = 4/34 (11%)
Query: 99 HHHRHHRAAATNPARYCCLSGCTQQDLLTLC-PY 131
HH + R + CCL+GCT+++L C PY
Sbjct: 165 HHPQRKRRGYSEK---CCLTGCTKEELSIACLPY 195
>gi|109148522 insulin- insulin-like growth factor 2 [Homo sapiens]
Length = 200
Score = 31.2 bits (69), Expect = 0.24
Identities = 21/55 (38%), Positives = 28/55 (50%), Gaps = 3/55 (5%)
Query: 8 WALVLLGPALVFALGPAPTPE-MREKLCGHHFVRALVRVCG--GPRWSTEARRPA 59
W +L AL+ GP P + + LCG H V AL VCG G ++ + RR A
Sbjct: 4 WMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREA 58
>gi|20143933 relaxin 2 isoform 1 preproprotein [Homo sapiens]
Length = 185
Score = 30.8 bits (68), Expect = 0.32
Identities = 35/155 (22%), Positives = 47/155 (30%), Gaps = 59/155 (38%)
Query: 32 KLCGHHFVRALVRVCGGPRWS---------TEARRPAT-------GGDRELLQWLERRHL 75
KLCG VRA + +CG WS + RP D E + +
Sbjct: 33 KLCGRELVRAQIAICGMSTWSKRSLSQEDAPQTPRPVAEIVPSFINKDTETINMMS--EF 90
Query: 76 LHGLVADSNLTLGPGLQPLPQTSHH-------------------HRHHRAAATNP----- 111
+ L + LTL LPQ H +R AA ++P
Sbjct: 91 VANLPQELKLTLSEMQPALPQLQQHVPVLKDSSLLFEEFKKLIRNRQSEAADSSPSELKY 150
Query: 112 -----------------ARYCCLSGCTQQDLLTLC 129
A CC GCT++ L C
Sbjct: 151 LGLDTHSRKKRQLYSALANKCCHVGCTKRSLARFC 185
>gi|5902052 relaxin 1 preproprotein [Homo sapiens]
Length = 185
Score = 29.6 bits (65), Expect = 0.70
Identities = 11/21 (52%), Positives = 13/21 (61%)
Query: 32 KLCGHHFVRALVRVCGGPRWS 52
KLCG VRA + +CG WS
Sbjct: 33 KLCGRELVRAQIAICGMSTWS 53
>gi|20143935 relaxin 2 isoform 2 [Homo sapiens]
Length = 117
Score = 29.6 bits (65), Expect = 0.70
Identities = 11/21 (52%), Positives = 13/21 (61%)
Query: 32 KLCGHHFVRALVRVCGGPRWS 52
KLCG VRA + +CG WS
Sbjct: 33 KLCGRELVRAQIAICGMSTWS 53
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 28.9 bits (63), Expect = 1.2
Identities = 14/30 (46%), Positives = 15/30 (50%)
Query: 93 PLPQTSHHHRHHRAAATNPARYCCLSGCTQ 122
PLPQ A NP R+CCLSG Q
Sbjct: 304 PLPQKEKLSLEPVLPARNPNRFCCLSGHDQ 333
>gi|13376253 ribonuclease P 21 [Homo sapiens]
Length = 154
Score = 28.1 bits (61), Expect = 2.1
Identities = 21/61 (34%), Positives = 25/61 (40%), Gaps = 10/61 (16%)
Query: 44 RVCGGPRWSTEARRPATGGDREL-----LQWLERRHLLHGLVADSNLTLGPGLQPLPQTS 98
R C G RW+ + R L L W +R G ADS LQPLP T+
Sbjct: 80 RRCRGQRWTVQTCLTCQRSQRFLNDPGHLLWGDRPEAQLGSQADSK-----PLQPLPNTA 134
Query: 99 H 99
H
Sbjct: 135 H 135
>gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens]
Length = 814
Score = 28.1 bits (61), Expect = 2.1
Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 6/49 (12%)
Query: 89 PGLQPLPQTSHHHRHHRAAAT--NPARYC-CLSG---CTQQDLLTLCPY 131
P Q + H H + T +P R C CL G C Q++ +LCPY
Sbjct: 246 PTCQGCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPY 294
>gi|54607124 RNA binding motif protein 15B [Homo sapiens]
Length = 890
Score = 28.1 bits (61), Expect = 2.1
Identities = 14/47 (29%), Positives = 19/47 (40%)
Query: 61 GGDRELLQWLERRHLLHGLVADSNLTLGPGLQPLPQTSHHHRHHRAA 107
G DR + + H G S+ +L + HHH HH AA
Sbjct: 627 GSDRTPERSRKENHSSEGTKESSSNSLSNSRHGAEERGHHHHHHEAA 673
>gi|91208437 GEM interacting protein [Homo sapiens]
Length = 970
Score = 28.1 bits (61), Expect = 2.1
Identities = 22/76 (28%), Positives = 32/76 (42%), Gaps = 1/76 (1%)
Query: 25 PTPEMREKLCGHHFVRALVRVCGGPRWSTEARRPATGGDRELLQWLERRHLLHGLVADSN 84
P+PE L G L+R GG + E + + +ELL W E+R A S
Sbjct: 70 PSPEGPVPLTGEELDLRLIRTKGGVDAALEYAKTWSRYAKELLAWTEKRASYELEFAKST 129
Query: 85 LTLG-PGLQPLPQTSH 99
+ + G + Q SH
Sbjct: 130 MKIAEAGKVSIQQQSH 145
>gi|10092665 sushi domain containing 2 [Homo sapiens]
Length = 822
Score = 27.7 bits (60), Expect = 2.7
Identities = 15/31 (48%), Positives = 18/31 (58%), Gaps = 2/31 (6%)
Query: 1 MDPRLPAWALVLLGPALVFALGPAPTPEMRE 31
M P L WAL+LL AL GP PT + +E
Sbjct: 1 MKPALLPWALLLLATAL--GPGPGPTADAQE 29
>gi|148233912 C1q and tumor necrosis factor related protein 4
[Homo sapiens]
Length = 329
Score = 27.3 bits (59), Expect = 3.5
Identities = 13/22 (59%), Positives = 14/22 (63%)
Query: 10 LVLLGPALVFALGPAPTPEMRE 31
L LLGPA +ALGP P P E
Sbjct: 6 LGLLGPAACWALGPTPGPGSSE 27
>gi|11967991 SRY-box 17 [Homo sapiens]
Length = 414
Score = 26.9 bits (58), Expect = 4.6
Identities = 17/55 (30%), Positives = 22/55 (40%), Gaps = 3/55 (5%)
Query: 49 PRWSTEARRPATGGDRELLQWLERRHLLHGLVADSNLTLGPGLQPLPQTSHHHRH 103
PR E P+ G LL H+ +G + G G Q PQ H H+H
Sbjct: 272 PRLGPEPAGPSIPG---LLAPPSALHVYYGAMGSPGAGGGRGFQMQPQHQHQHQH 323
>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
Length = 532
Score = 26.9 bits (58), Expect = 4.6
Identities = 10/33 (30%), Positives = 13/33 (39%)
Query: 76 LHGLVADSNLTLGPGLQPLPQTSHHHRHHRAAA 108
LH N+ +G + HHH HH A
Sbjct: 210 LHNQYGPMNMNMGMNMAAAAAHHHHHHHHHPGA 242
>gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo
sapiens]
Length = 735
Score = 26.9 bits (58), Expect = 4.6
Identities = 15/44 (34%), Positives = 22/44 (50%)
Query: 48 GPRWSTEARRPATGGDRELLQWLERRHLLHGLVADSNLTLGPGL 91
GP +R PA G + L+ RR +L G + +LGPG+
Sbjct: 57 GPSSPEASRSPARGAYLQSLEPSSRRWVLGGAKPAEDTSLGPGV 100
>gi|223633890 hypothetical protein LOC729956 [Homo sapiens]
Length = 538
Score = 26.6 bits (57), Expect = 6.0
Identities = 15/30 (50%), Positives = 16/30 (53%), Gaps = 5/30 (16%)
Query: 83 SNLTLGPG-----LQPLPQTSHHHRHHRAA 107
SNL LGPG L+ LP S H HH A
Sbjct: 452 SNLLLGPGGPPTPLRGLPPPSSLHAHHHHA 481
>gi|239752128 PREDICTED: hypothetical protein [Homo sapiens]
Length = 149
Score = 26.6 bits (57), Expect = 6.0
Identities = 14/26 (53%), Positives = 14/26 (53%), Gaps = 3/26 (11%)
Query: 48 GPRWSTEARRPATGGDRELLQWLERR 73
GPRWS EA A GG WL RR
Sbjct: 9 GPRWSREAPPEARGG---WTMWLGRR 31
>gi|122937233 discs, large (Drosophila) homolog-associated protein 3
[Homo sapiens]
Length = 979
Score = 26.6 bits (57), Expect = 6.0
Identities = 11/17 (64%), Positives = 11/17 (64%), Gaps = 1/17 (5%)
Query: 88 GPGLQPLPQTSHHHRHH 104
GPG P TSHHH HH
Sbjct: 213 GPGSGG-PHTSHHHHHH 228
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 26.6 bits (57), Expect = 6.0
Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 6/38 (15%)
Query: 100 HHRHHRAAAT--NPARYC-CLSG---CTQQDLLTLCPY 131
H H + T +P R C CL G C Q++ +LCPY
Sbjct: 199 HWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPY 236
>gi|42476101 TFIIA alpha, p55 isoform 2 [Homo sapiens]
Length = 337
Score = 26.6 bits (57), Expect = 6.0
Identities = 14/35 (40%), Positives = 17/35 (48%), Gaps = 2/35 (5%)
Query: 92 QPLPQTSHHHRHHRAAATNPARYCCLSGCTQQDLL 126
QP Q HHH HH+ A P + TQQ L+
Sbjct: 36 QPQQQQHHHHHHHQQA--QPQQTVPQQAQTQQVLI 68
>gi|7706735 TFIIA alpha, p55 isoform 1 [Homo sapiens]
Length = 376
Score = 26.6 bits (57), Expect = 6.0
Identities = 14/35 (40%), Positives = 17/35 (48%), Gaps = 2/35 (5%)
Query: 92 QPLPQTSHHHRHHRAAATNPARYCCLSGCTQQDLL 126
QP Q HHH HH+ A P + TQQ L+
Sbjct: 75 QPQQQQHHHHHHHQQA--QPQQTVPQQAQTQQVLI 107
>gi|21361411 HMG-box transcription factor 1 [Homo sapiens]
Length = 514
Score = 26.6 bits (57), Expect = 6.0
Identities = 24/95 (25%), Positives = 36/95 (37%), Gaps = 16/95 (16%)
Query: 51 WSTEARRPATGGDRELLQ--WLERRHLLHGLVADSNLTLGPGLQPLPQTS-------HHH 101
W TE AT L+Q + R +H + +L P+ +S HHH
Sbjct: 110 WLTELANIATSPQSPLMQCSFYNRSSPVHIIATSKSLHSYARPPPVSSSSKSEPAFPHHH 169
Query: 102 -------RHHRAAATNPARYCCLSGCTQQDLLTLC 129
RH RA + + + C+S + D L C
Sbjct: 170 WKEETPVRHERANSESESGIFCMSSLSDDDDLGWC 204
>gi|169162130 PREDICTED: tetratricopeptide repeat domain 34 [Homo
sapiens]
Length = 901
Score = 26.2 bits (56), Expect = 7.8
Identities = 12/27 (44%), Positives = 14/27 (51%), Gaps = 1/27 (3%)
Query: 104 HRAAATNPARYCCLSGCTQQDLLTLCP 130
HRA R+CC C + DL LCP
Sbjct: 109 HRAETQGAHRHCCDGNC-RADLPPLCP 134
>gi|145580586 kintoun isoform 2 [Homo sapiens]
Length = 789
Score = 26.2 bits (56), Expect = 7.8
Identities = 15/42 (35%), Positives = 18/42 (42%), Gaps = 2/42 (4%)
Query: 23 PAPTPEMREKLCGHHFVRALVRVCGGPRWSTEARRPATGGDR 64
P P +R L G R V VC + RP +GGDR
Sbjct: 72 PEPGHVLRTSLDGAR--RCFVNVCSNALVGAPSSRPGSGGDR 111
>gi|145580588 kintoun isoform 1 [Homo sapiens]
Length = 837
Score = 26.2 bits (56), Expect = 7.8
Identities = 15/42 (35%), Positives = 18/42 (42%), Gaps = 2/42 (4%)
Query: 23 PAPTPEMREKLCGHHFVRALVRVCGGPRWSTEARRPATGGDR 64
P P +R L G R V VC + RP +GGDR
Sbjct: 72 PEPGHVLRTSLDGAR--RCFVNVCSNALVGAPSSRPGSGGDR 111
>gi|5032115 sprouty 2 [Homo sapiens]
Length = 315
Score = 26.2 bits (56), Expect = 7.8
Identities = 9/17 (52%), Positives = 12/17 (70%)
Query: 89 PGLQPLPQTSHHHRHHR 105
PGL+P P+ S H+H R
Sbjct: 65 PGLKPAPRPSTQHKHER 81
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.140 0.480
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,826,032
Number of Sequences: 37866
Number of extensions: 343502
Number of successful extensions: 1506
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1463
Number of HSP's gapped (non-prelim): 53
length of query: 131
length of database: 18,247,518
effective HSP length: 91
effective length of query: 40
effective length of database: 14,801,712
effective search space: 592068480
effective search space used: 592068480
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Search text |
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.