Guide to the Human Genome
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Search of human proteins with 38201670

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38201670 inhibitor of growth family, member 4 isoform 1
[Homo sapiens]
         (248 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38201670 inhibitor of growth family, member 4 isoform 1 [Homo...   508   e-144
gi|189083821 inhibitor of growth family, member 4 isoform 9 [Hom...   501   e-142
gi|189083828 inhibitor of growth family, member 4 isoform 4 [Hom...   497   e-141
gi|189083826 inhibitor of growth family, member 4 isoform 3 [Hom...   495   e-140
gi|189083830 inhibitor of growth family, member 4 isoform 5 [Hom...   439   e-123
gi|18644730 inhibitor of growth family, member 5 [Homo sapiens]       348   2e-96
gi|189083832 inhibitor of growth family, member 4 isoform 6 [Hom...   318   2e-87
gi|38201667 inhibitor of growth family, member 1 isoform A [Homo...   190   9e-49
gi|4504695 inhibitor of growth family, member 2 [Homo sapiens]        172   2e-43
gi|38201663 inhibitor of growth family, member 1 isoform C [Homo...   149   2e-36
gi|38201661 inhibitor of growth family, member 1 isoform D [Homo...   149   2e-36
gi|38201665 inhibitor of growth family, member 1 isoform B [Homo...   145   2e-35
gi|38201655 inhibitor of growth family, member 3 isoform 1 [Homo...   112   2e-25
gi|38201659 inhibitor of growth family, member 3 isoform 3 [Homo...    60   1e-09
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho...    50   2e-06
gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo ...    48   7e-06
gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo ...    48   7e-06
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    47   2e-05
gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens]       45   8e-05
gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]       45   8e-05
gi|55770834 centromere protein F [Homo sapiens]                        41   8e-04
gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]      41   0.001
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]                41   0.001
gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo ...    41   0.001
gi|57546899 myeloid/lymphoid or mixed-lineage leukemia transloca...    40   0.002
gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocat...    40   0.002
gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithora...    39   0.003
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa...    39   0.003
gi|154354987 hook homolog 2 isoform 2 [Homo sapiens]                   39   0.003
gi|154354985 hook homolog 2 isoform 1 [Homo sapiens]                   39   0.003

>gi|38201670 inhibitor of growth family, member 4 isoform 1 [Homo
           sapiens]
          Length = 248

 Score =  508 bits (1307), Expect = e-144
 Identities = 248/248 (100%), Positives = 248/248 (100%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE
Sbjct: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120

Query: 121 YDSSSSKGKKSRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSV 180
           YDSSSSKGKKSRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSV
Sbjct: 121 YDSSSSKGKKSRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSV 180

Query: 181 HPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPR 240
           HPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPR
Sbjct: 181 HPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPR 240

Query: 241 CSQERKKK 248
           CSQERKKK
Sbjct: 241 CSQERKKK 248


>gi|189083821 inhibitor of growth family, member 4 isoform 9 [Homo
           sapiens]
          Length = 249

 Score =  501 bits (1291), Expect = e-142
 Identities = 247/249 (99%), Positives = 247/249 (99%), Gaps = 1/249 (0%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE
Sbjct: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120

Query: 121 YDSSSSKGKKS-RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 179
           YDSSSSKGKK  RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS
Sbjct: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 180

Query: 180 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 239
           VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP
Sbjct: 181 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 240

Query: 240 RCSQERKKK 248
           RCSQERKKK
Sbjct: 241 RCSQERKKK 249


>gi|189083828 inhibitor of growth family, member 4 isoform 4 [Homo
           sapiens]
          Length = 245

 Score =  497 bits (1279), Expect = e-141
 Identities = 245/248 (98%), Positives = 245/248 (98%), Gaps = 3/248 (1%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE
Sbjct: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120

Query: 121 YDSSSSKGKKSRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSV 180
           YDSSSSKG   RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSV
Sbjct: 121 YDSSSSKG---RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSV 177

Query: 181 HPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPR 240
           HPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPR
Sbjct: 178 HPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPR 237

Query: 241 CSQERKKK 248
           CSQERKKK
Sbjct: 238 CSQERKKK 245


>gi|189083826 inhibitor of growth family, member 4 isoform 3 [Homo
           sapiens]
          Length = 246

 Score =  495 bits (1275), Expect = e-140
 Identities = 244/248 (98%), Positives = 245/248 (98%), Gaps = 2/248 (0%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE
Sbjct: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120

Query: 121 YDSSSSKGKKSRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSV 180
           YDSSSSK  + RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSV
Sbjct: 121 YDSSSSK--EGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSV 178

Query: 181 HPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPR 240
           HPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPR
Sbjct: 179 HPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPR 238

Query: 241 CSQERKKK 248
           CSQERKKK
Sbjct: 239 CSQERKKK 246


>gi|189083830 inhibitor of growth family, member 4 isoform 5 [Homo
           sapiens]
          Length = 225

 Score =  439 bits (1129), Expect = e-123
 Identities = 222/249 (89%), Positives = 223/249 (89%), Gaps = 25/249 (10%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MAAGMYLEHYLD+                        LKAEIDKLATEYMSSARSLSSEE
Sbjct: 1   MAAGMYLEHYLDN------------------------LKAEIDKLATEYMSSARSLSSEE 36

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 37  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 96

Query: 121 YDSSSSKGKKS-RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 179
           YDSSSSKGKK  RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS
Sbjct: 97  YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 156

Query: 180 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 239
           VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP
Sbjct: 157 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 216

Query: 240 RCSQERKKK 248
           RCSQERKKK
Sbjct: 217 RCSQERKKK 225


>gi|18644730 inhibitor of growth family, member 5 [Homo sapiens]
          Length = 240

 Score =  348 bits (893), Expect = 2e-96
 Identities = 173/249 (69%), Positives = 202/249 (81%), Gaps = 11/249 (4%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MA  MYLEHYLDSIENLP ELQRNFQLMR+LDQRTED KAEID LA EY+S+ ++LS ++
Sbjct: 1   MATAMYLEHYLDSIENLPCELQRNFQLMRELDQRTEDKKAEIDILAAEYISTVKTLSPDQ 60

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           ++  L++IQ AY KCKE+ DDKVQLAMQTYEMVDKHIRRLD DLARFEADLK+K +E SD
Sbjct: 61  RVERLQKIQNAYSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFEADLKDK-MEGSD 119

Query: 121 YDSSSSKG-KKSRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGS 179
           ++SS  +G KK R QKEK+ +R R + + S+E+ PK  + K        E+   + T  S
Sbjct: 120 FESSGGRGLKKGRGQKEKRGSRGRGR-RTSEEDTPKKKKHK-----GGSEF---TDTILS 170

Query: 180 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 239
           VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDC IEWFHFACV LTTKP+GKWFCP
Sbjct: 171 VHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVDLTTKPKGKWFCP 230

Query: 240 RCSQERKKK 248
           RC QE++KK
Sbjct: 231 RCVQEKRKK 239


>gi|189083832 inhibitor of growth family, member 4 isoform 6 [Homo
           sapiens]
          Length = 179

 Score =  318 bits (816), Expect = 2e-87
 Identities = 167/172 (97%), Positives = 167/172 (97%), Gaps = 1/172 (0%)

Query: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
           MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE
Sbjct: 1   MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60

Query: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120
           KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD
Sbjct: 61  KLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSD 120

Query: 121 YDSSSSKG-KKSRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYG 171
           YDSSSSKG KK RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRT P  G
Sbjct: 121 YDSSSSKGKKKGRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTVPLSG 172


>gi|38201667 inhibitor of growth family, member 1 isoform A [Homo
           sapiens]
          Length = 279

 Score =  190 bits (483), Expect = 9e-49
 Identities = 96/253 (37%), Positives = 148/253 (58%), Gaps = 16/253 (6%)

Query: 6   YLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALL 65
           Y+E YLDSIE+LPF+LQRN  LMR++D + +++  E+D+    Y   +R     +K  +L
Sbjct: 15  YVEDYLDSIESLPFDLQRNVSLMREIDAKYQEILKELDEC---YERFSRETDGAQKRRML 71

Query: 66  KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEA--DLKEKQIESSDYDS 123
             +Q A  + +E GD+K+Q+  Q  E+V+   R++D+ +  FEA  +L +    S    +
Sbjct: 72  HCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKAGA 131

Query: 124 SSSKGKKS---------RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPS 174
              KG+ +         R+++++      +   N D +   +   K K  +TS +     
Sbjct: 132 DRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKRSK 191

Query: 175 VTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRG 234
               +   +   D+P+DPNEPTYCLC+QVSYGEMIGCDN +C IEWFHF+CVGL  KP+G
Sbjct: 192 AK--AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKG 249

Query: 235 KWFCPRCSQERKK 247
           KW+CP+C  E +K
Sbjct: 250 KWYCPKCRGENEK 262


>gi|4504695 inhibitor of growth family, member 2 [Homo sapiens]
          Length = 280

 Score =  172 bits (436), Expect = 2e-43
 Identities = 89/252 (35%), Positives = 141/252 (55%), Gaps = 24/252 (9%)

Query: 6   YLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALL 65
           Y++ YL+ +E+LP ++QRN  ++R+LD + ++   EID +  +Y          +K  L 
Sbjct: 27  YVQDYLECVESLPHDMQRNVSVLRELDNKYQETLKEIDDVYEKYKKED---DLNQKKRLQ 83

Query: 66  KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDT------DLARFEADLKEKQIESS 119
           + +Q A    +E GD+K+Q+  Q  E+V+   R+++       D A  E    + +++SS
Sbjct: 84  QLLQRALINSQELGDEKIQIVTQMLELVENRARQMELHSQCFQDPAESERASDKAKMDSS 143

Query: 120 DYDSSSSKGKKSRTQKEKKAARARSKGKNSDEEAPKTAQ----KKLKLVRTSPEYGMPSV 175
             + SS + ++ RT + +      +  ++ D++ PK  +    KK K  +   E     V
Sbjct: 144 QPERSSRRPRRQRTSESRDLCHMANGIEDCDDQPPKEKKSKSAKKKKRSKAKQEREASPV 203

Query: 176 TFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGK 235
            F            +DPNEPTYCLC+QVSYGEMIGCDN  C IEWFHF+CV LT KP+GK
Sbjct: 204 EFA-----------IDPNEPTYCLCNQVSYGEMIGCDNEQCPIEWFHFSCVSLTYKPKGK 252

Query: 236 WFCPRCSQERKK 247
           W+CP+C  + +K
Sbjct: 253 WYCPKCRGDNEK 264


>gi|38201663 inhibitor of growth family, member 1 isoform C [Homo
           sapiens]
          Length = 235

 Score =  149 bits (377), Expect = 2e-36
 Identities = 75/210 (35%), Positives = 116/210 (55%), Gaps = 13/210 (6%)

Query: 49  YMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFE 108
           Y   +R     +K  +L  +Q A  + +E GD+K+Q+  Q  E+V+   R++D+ +  FE
Sbjct: 11  YERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFE 70

Query: 109 A--DLKEKQIESSDYDSSSSKGKKS---------RTQKEKKAARARSKGKNSDEEAPKTA 157
           A  +L +    S    +   KG+ +         R+++++      +   N D +   + 
Sbjct: 71  AQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASG 130

Query: 158 QKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCS 217
             K K  +TS +         +   +   D+P+DPNEPTYCLC+QVSYGEMIGCDN +C 
Sbjct: 131 TPKEKKAKTSKKKKRSKAK--AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECP 188

Query: 218 IEWFHFACVGLTTKPRGKWFCPRCSQERKK 247
           IEWFHF+CVGL  KP+GKW+CP+C  E +K
Sbjct: 189 IEWFHFSCVGLNHKPKGKWYCPKCRGENEK 218


>gi|38201661 inhibitor of growth family, member 1 isoform D [Homo
           sapiens]
          Length = 422

 Score =  149 bits (377), Expect = 2e-36
 Identities = 75/210 (35%), Positives = 116/210 (55%), Gaps = 13/210 (6%)

Query: 49  YMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFE 108
           Y   +R     +K  +L  +Q A  + +E GD+K+Q+  Q  E+V+   R++D+ +  FE
Sbjct: 198 YERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFE 257

Query: 109 A--DLKEKQIESSDYDSSSSKGKKS---------RTQKEKKAARARSKGKNSDEEAPKTA 157
           A  +L +    S    +   KG+ +         R+++++      +   N D +   + 
Sbjct: 258 AQQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASG 317

Query: 158 QKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCS 217
             K K  +TS +         +   +   D+P+DPNEPTYCLC+QVSYGEMIGCDN +C 
Sbjct: 318 TPKEKKAKTSKKKKRSKAK--AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECP 375

Query: 218 IEWFHFACVGLTTKPRGKWFCPRCSQERKK 247
           IEWFHF+CVGL  KP+GKW+CP+C  E +K
Sbjct: 376 IEWFHFSCVGLNHKPKGKWYCPKCRGENEK 405


>gi|38201665 inhibitor of growth family, member 1 isoform B [Homo
           sapiens]
          Length = 210

 Score =  145 bits (367), Expect = 2e-35
 Identities = 72/195 (36%), Positives = 111/195 (56%), Gaps = 13/195 (6%)

Query: 64  LLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEA--DLKEKQIESSDY 121
           +L  +Q A  + +E GD+K+Q+  Q  E+V+   R++D+ +  FEA  +L +    S   
Sbjct: 1   MLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTAGNSGKA 60

Query: 122 DSSSSKGKKS---------RTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGM 172
            +   KG+ +         R+++++      +   N D +   +   K K  +TS +   
Sbjct: 61  GADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKR 120

Query: 173 PSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKP 232
                 +   +   D+P+DPNEPTYCLC+QVSYGEMIGCDN +C IEWFHF+CVGL  KP
Sbjct: 121 SKAK--AEREASPADLPIDPNEPTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKP 178

Query: 233 RGKWFCPRCSQERKK 247
           +GKW+CP+C  E +K
Sbjct: 179 KGKWYCPKCRGENEK 193


>gi|38201655 inhibitor of growth family, member 3 isoform 1 [Homo
           sapiens]
          Length = 418

 Score =  112 bits (281), Expect = 2e-25
 Identities = 47/126 (37%), Positives = 71/126 (56%), Gaps = 3/126 (2%)

Query: 123 SSSSKGKKSRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSVHP 182
           SS++  +  R  K    + ++    +S   +  +      +V+   E    +        
Sbjct: 291 SSAADSRSGRKSKNNNKSSSQQSSSSSSSSSLSSCSSSSTVVQ---EISQQTTVVPESDS 347

Query: 183 SDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCS 242
           +  +D   DPNEP YC+C+QVSYGEM+GCDN DC IEWFH+ CVGLT  P+GKW+CP+C+
Sbjct: 348 NSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWYCPQCT 407

Query: 243 QERKKK 248
              K++
Sbjct: 408 AAMKRR 413



 Score = 84.7 bits (208), Expect = 7e-17
 Identities = 39/108 (36%), Positives = 71/108 (65%)

Query: 5   MYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLAL 64
           +YLE YL+ IE LP +L+  F  MR++D + ++   ++++  +E+  +A+    E +   
Sbjct: 2   LYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREEQ 61

Query: 65  LKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLK 112
           +  I++ Y K  E  D+KVQLA Q Y++VD+H+R+LD +LA+F+ +L+
Sbjct: 62  MASIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELE 109


>gi|38201659 inhibitor of growth family, member 3 isoform 3 [Homo
          sapiens]
          Length = 92

 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 29/88 (32%), Positives = 53/88 (60%)

Query: 5  MYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLAL 64
          +YLE YL+ IE LP +L+  F  MR++D + ++   ++++  +E+  +A+    E +   
Sbjct: 2  LYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREEQ 61

Query: 65 LKQIQEAYGKCKEFGDDKVQLAMQTYEM 92
          +  I++ Y K  E  D+KVQLA Q Y++
Sbjct: 62 MASIKKDYYKALEDADEKVQLANQIYDL 89


>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
           sapiens]
          Length = 929

 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 20/43 (46%), Positives = 30/43 (69%), Gaps = 5/43 (11%)

Query: 208 MIGCDNPDCSIEWFHFACVGLTTKP--RGKWFCPRCSQERKKK 248
           MIGCD+ D   +W+H+ CVG+ T P    +WFCP+C+ ++K K
Sbjct: 880 MIGCDDCD---DWYHWPCVGIMTAPPEEMQWFCPKCANKKKDK 919



 Score = 29.3 bits (64), Expect = 3.3
 Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 9/79 (11%)

Query: 76  KEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKSRTQK 135
           KE   D  +  ++ +E VD  ++  D  L R E   KEK     D      KGKK + ++
Sbjct: 581 KEEEADPYKFKIKEFEDVDPKVKLKD-GLVRKE---KEKH---KDKKKDREKGKKDKDKR 633

Query: 136 EKKAARARSKGKNSDEEAP 154
           EK+  + + KG+    +AP
Sbjct: 634 EKE--KVKDKGREDKMKAP 650



 Score = 28.5 bits (62), Expect = 5.7
 Identities = 17/68 (25%), Positives = 36/68 (52%), Gaps = 3/68 (4%)

Query: 111 LKEKQIESSDYDSSSSKGKKSRTQKEKKAARARSKGKNSDEEAPKTAQKKLKL--VRTSP 168
           +KEK+ +  D      K +K + +KEK+  + + + +  ++E  K   +K+K+  V  +P
Sbjct: 696 VKEKE-KKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKIKVEPVALAP 754

Query: 169 EYGMPSVT 176
              +P +T
Sbjct: 755 SPVIPRLT 762


>gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo
           sapiens]
          Length = 1188

 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 25/156 (16%)

Query: 104 LARFEADLKEKQIESSDYDS-SSSKGKKSRT-QKEKKAARARSKGKNSDEEAPKTAQKKL 161
           LA  E   +++ +E  D  + S   G   RT QK K  +   S   +S ++   +  KK 
Sbjct: 6   LAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTSPIKKK 65

Query: 162 KL-------------VRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYC-LCHQVSYGE 207
           K              +R  P Y M      +  P DV+  P D     YC +CH+   G+
Sbjct: 66  KKPGLLNSNNKEQSELRHGPFYYMKQPL--TTDPVDVV--PQDGRNDFYCWVCHRE--GQ 119

Query: 208 MIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQ 243
           ++ C+        +H  C+ LT++P G WFCP C +
Sbjct: 120 VLCCE---LCPRVYHAKCLRLTSEPEGDWFCPECEK 152


>gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo
           sapiens]
          Length = 1160

 Score = 48.1 bits (113), Expect = 7e-06
 Identities = 43/156 (27%), Positives = 67/156 (42%), Gaps = 25/156 (16%)

Query: 104 LARFEADLKEKQIESSDYDS-SSSKGKKSRT-QKEKKAARARSKGKNSDEEAPKTAQKKL 161
           LA  E   +++ +E  D  + S   G   RT QK K  +   S   +S ++   +  KK 
Sbjct: 6   LAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTSPIKKK 65

Query: 162 KL-------------VRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYC-LCHQVSYGE 207
           K              +R  P Y M      +  P DV+  P D     YC +CH+   G+
Sbjct: 66  KKPGLLNSNNKEQSELRHGPFYYMKQPL--TTDPVDVV--PQDGRNDFYCWVCHRE--GQ 119

Query: 208 MIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQ 243
           ++ C+        +H  C+ LT++P G WFCP C +
Sbjct: 120 VLCCE---LCPRVYHAKCLRLTSEPEGDWFCPECEK 152


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 43/171 (25%), Positives = 79/171 (46%), Gaps = 12/171 (7%)

Query: 1    MAAGMYLEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEE 60
            M A +  +H  DS+  L  ++    ++ + L++   + K EID L++   S ++S ++ E
Sbjct: 1189 MVAALRKKH-ADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLE 1247

Query: 61   KL--ALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIES 118
            K+   L  Q+ EA GK +E      +L  Q          RL T+       L+EK+   
Sbjct: 1248 KICRTLEDQLSEARGKNEEIQRSLSELTTQK--------SRLQTEAGELSRQLEEKESIV 1299

Query: 119  SDYDSSSSKGKKSRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPE 169
            S   S S +    +T++ K+     +K KN+   A ++++    L+R   E
Sbjct: 1300 SQL-SRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYE 1349



 Score = 27.7 bits (60), Expect = 9.7
 Identities = 41/176 (23%), Positives = 75/176 (42%), Gaps = 32/176 (18%)

Query: 7    LEHYLDSIENLPFELQRNFQLMRDLDQRT-EDLKAEIDKLATEYMSSAR----------S 55
            L   L  ++    +L R  + +++  Q+  +DL+AE DK+ +   + ++          S
Sbjct: 979  LTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESS 1038

Query: 56   LSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQ 115
            L  E+KL    ++     K K  GD K         +  + I  L+ D  + +  LK+K 
Sbjct: 1039 LEQEKKL----RVDLERNKRKLEGDLK---------LAQESILDLENDKQQLDERLKKKD 1085

Query: 116  IESSDYDSSSSKGKKSRT-----QKEKKAARARSKGKNSDEEAPKTAQKKLKLVRT 166
             E   Y    SK +  +T     QK+ K  +AR +    + EA +  + K +  R+
Sbjct: 1086 FE---YCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRS 1138


>gi|156142182 CXXC finger 1 (PHD domain) isoform 1 [Homo sapiens]
          Length = 660

 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 7/59 (11%)

Query: 193 NEPTYCLCHQVSYG-EMIGCDNPDCSIEWFHFACVGLT---TKPRGKWFCPRCSQERKK 247
           N P YC+C +      MIGCDN  C+ EWFH  C+ +T    K   +W+C  C ++  K
Sbjct: 24  NAPIYCICRKPDINCFMIGCDN--CN-EWFHGDCIRITEKMAKAIREWYCRECREKDPK 79


>gi|156142180 CXXC finger 1 (PHD domain) isoform 2 [Homo sapiens]
          Length = 656

 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 23/59 (38%), Positives = 32/59 (54%), Gaps = 7/59 (11%)

Query: 193 NEPTYCLCHQVSYG-EMIGCDNPDCSIEWFHFACVGLT---TKPRGKWFCPRCSQERKK 247
           N P YC+C +      MIGCDN  C+ EWFH  C+ +T    K   +W+C  C ++  K
Sbjct: 24  NAPIYCICRKPDINCFMIGCDN--CN-EWFHGDCIRITEKMAKAIREWYCRECREKDPK 79


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 41.2 bits (95), Expect = 8e-04
 Identities = 42/162 (25%), Positives = 64/162 (39%), Gaps = 26/162 (16%)

Query: 12   DSIENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLS---------SEEKL 62
            D +ENL  ELQ + +    +    E+ KAE++ L T+    ARSL            EK 
Sbjct: 2154 DKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKE 2213

Query: 63   ALLKQIQEAYGKCKEFG----------DDKVQLAMQ-------TYEMVDKHIRRLDTDLA 105
             L KQIQE  G+  E            ++K Q  +Q         EM+   ++ L+  +A
Sbjct: 2214 NLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVA 2273

Query: 106  RFEADLKEKQIESSDYDSSSSKGKKSRTQKEKKAARARSKGK 147
                D +  +      D    +  + R   EK  AR  +  K
Sbjct: 2274 ALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEK 2315



 Score = 35.4 bits (80), Expect = 0.046
 Identities = 33/174 (18%), Positives = 81/174 (46%), Gaps = 13/174 (7%)

Query: 14   IENLPFELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALLKQIQEAYG 73
            + NL  EL++  Q+++  +   +D   E+ + + + + +   L+  +K++ ++++ +   
Sbjct: 2558 LRNLTVELEQKIQVLQSKNASLQDT-LEVLQSSYKNLENELELTKMDKMSFVEKVNKMTA 2616

Query: 74   KCKEFGDDKVQLAMQTYEMVDK----------HIRRLDTDLARFEADLKEKQIESSDYDS 123
            K  E   +  ++A +T E+ ++           ++ L  ++   +  LKE  +E+S+   
Sbjct: 2617 KETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKK 2676

Query: 124  SSSKGKKSRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTF 177
            S     K + +KE K     ++ +    EA K  Q    L+ T+ +Y +   T+
Sbjct: 2677 SLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQ--ALLLDTNKQYEVEIQTY 2728


>gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]
          Length = 1544

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 32/116 (27%), Positives = 55/116 (47%), Gaps = 9/116 (7%)

Query: 129  KKSRTQKEKKAARARSKGKNSDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDM 188
            KK RT K+KK   +  K  N+ +      ++  +LVR++  + +PS T  S       + 
Sbjct: 1428 KKMRTPKKKKIKLSHPKDMNNFK---LERERSYELVRSAETHSLPSDTSYSEQEDSEDED 1484

Query: 189  PVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGK--WFCPRCS 242
             + P     CL  +    + + CD   C+ +WFH  CVG++ +   K  + C RC+
Sbjct: 1485 AICP--AVSCLQPEGDEVDWVQCDG-SCN-QWFHQVCVGVSPEMAEKEDYICVRCT 1536



 Score = 33.1 bits (74), Expect = 0.23
 Identities = 17/60 (28%), Positives = 27/60 (45%), Gaps = 5/60 (8%)

Query: 189  PVDPNEPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGK--WFCPRCSQERK 246
            P+   +   CLC +     MI C+      + FH +CV + +  +G   W CP C +  K
Sbjct: 1170 PLQDVDIKICLCQKAPAAPMIQCE---LCRDAFHTSCVAVPSISQGLRIWLCPHCRRSEK 1226


>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
          Length = 1437

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 16/34 (47%), Positives = 21/34 (61%), Gaps = 1/34 (2%)

Query: 206  GEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCP 239
            GE++ CD  DC  + +H  C+ LT  P GKW CP
Sbjct: 1331 GELVMCDKKDCP-KAYHLLCLNLTQPPYGKWECP 1363



 Score = 32.3 bits (72), Expect = 0.39
 Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 2/46 (4%)

Query: 196 TYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRC 241
           T C   + S   +I C+   C  + FH  C+GL + P  K+ C  C
Sbjct: 702 TVCQICESSGDSLIPCEGECC--KHFHLECLGLASLPDSKFICMEC 745


>gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo
           sapiens]
          Length = 1135

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 36/143 (25%), Positives = 60/143 (41%), Gaps = 24/143 (16%)

Query: 104 LARFEADLKEKQIESSDYDS-SSSKGKKSRT-QKEKKAARARSKGKNSDEEAPKTAQKKL 161
           LA  E   +++ +E  D  + S   G   RT QK K  +   S   +S ++   +  KK 
Sbjct: 6   LAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTSPIKKK 65

Query: 162 KLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYC-LCHQVSYGEMIGCDNPDCSIEW 220
           K          P +   +       +   D     YC +CH+   G+++ C+        
Sbjct: 66  K---------KPGLLNSN-------NKEQDGRNDFYCWVCHRE--GQVLCCE---LCPRV 104

Query: 221 FHFACVGLTTKPRGKWFCPRCSQ 243
           +H  C+ LT++P G WFCP C +
Sbjct: 105 YHAKCLRLTSEPEGDWFCPECEK 127


>gi|57546899 myeloid/lymphoid or mixed-lineage leukemia translocated
           to, 10 isoform b [Homo sapiens]
          Length = 1011

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 2/39 (5%)

Query: 208 MIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRC-SQER 245
           ++ CD   CS+   H AC G+   P G WFC +C SQER
Sbjct: 39  LVYCDGHGCSVA-VHQACYGIVQVPTGPWFCRKCESQER 76


>gi|4757726 myeloid/lymphoid or mixed-lineage leukemia translocated
           to, 10 isoform a [Homo sapiens]
          Length = 1027

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 2/39 (5%)

Query: 208 MIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRC-SQER 245
           ++ CD   CS+   H AC G+   P G WFC +C SQER
Sbjct: 39  LVYCDGHGCSVA-VHQACYGIVQVPTGPWFCRKCESQER 76


>gi|57222568 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 6 [Homo sapiens]
          Length = 1093

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 18/39 (46%), Positives = 23/39 (58%), Gaps = 2/39 (5%)

Query: 208 MIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRC-SQER 245
           ++ CD   CS+   H AC G+   P G WFC +C SQER
Sbjct: 22  LVYCDGHACSVA-VHQACYGIVQVPTGPWFCRKCESQER 59


>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
           sapiens]
          Length = 1954

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 36/142 (25%), Positives = 57/142 (40%), Gaps = 16/142 (11%)

Query: 114 KQIESSDYDSSSSKGKKSRTQKEKKA--ARARSKGKNSDEEAPKTAQKKLKLVRTSPEYG 171
           K+I+ S       KGKK+   K +    +  R KG +S+E+  + +      + ++    
Sbjct: 254 KKIKGSKDGKKKGKGKKTAGLKFRFGGISNKRKKGSSSEEDEREESDFDSASIHSASVRS 313

Query: 172 MPSVTFGSVHPSDVLDMPVDPNE------PTYC-LCHQVSYGEMIGCDNPDCSIEWFHFA 224
             S   G           +D  +        YC +C Q   GE+I CD    +   +H  
Sbjct: 314 ECSAALGKKSKRRRKKKRIDDGDGYETDHQDYCEVCQQG--GEIILCDTCPRA---YHLV 368

Query: 225 CVG--LTTKPRGKWFCPRCSQE 244
           C+   L   P GKW CP C +E
Sbjct: 369 CLDPELEKAPEGKWSCPHCEKE 390



 Score = 38.9 bits (89), Expect = 0.004
 Identities = 24/76 (31%), Positives = 41/76 (53%), Gaps = 2/76 (2%)

Query: 103 DLARFEADLKEK-QIESSDYDSSSSKGKKSRTQKEKKAARARSKGKNSDEEAPKTAQKKL 161
           +L+  E DL+EK + E SDY  +  K KK + +KEKKA R + K ++ D+      ++  
Sbjct: 74  ELSENEEDLEEKSESEGSDYSPNKKKKKKLKDKKEKKAKR-KKKDEDEDDNDDGCLKEPK 132

Query: 162 KLVRTSPEYGMPSVTF 177
              +   E+G+  V +
Sbjct: 133 SSGQLMAEWGLDDVDY 148



 Score = 32.0 bits (71), Expect = 0.51
 Identities = 15/39 (38%), Positives = 21/39 (53%), Gaps = 5/39 (12%)

Query: 206 GEMIGCDNPDCSIEWFHFACVG--LTTKPRGKWFCPRCS 242
           GE++ CD    S   +H  C+   L   P G+W CPRC+
Sbjct: 426 GELLCCDACPSS---YHLHCLNPPLPEIPNGEWLCPRCT 461


>gi|154354987 hook homolog 2 isoform 2 [Homo sapiens]
          Length = 717

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 20/162 (12%)

Query: 7   LEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAE-IDKLATEYMSSARSLSSEEKLALL 65
           LE +L  +     ELQR  + + +L+  T+   A  I++L             ++K A L
Sbjct: 541 LEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHNL---------QKKDADL 591

Query: 66  KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSS 125
           + ++E Y +      DK ++ MQT E   +       +L      L+E+ +     +   
Sbjct: 592 RAMEERYRRYV----DKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIRHLEMDF 647

Query: 126 SKGKKSRTQKEKKAARA------RSKGKNSDEEAPKTAQKKL 161
            K +  R Q+EK    A        + +  +E AP  AQ  L
Sbjct: 648 EKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFL 689



 Score = 31.6 bits (70), Expect = 0.67
 Identities = 36/158 (22%), Positives = 72/158 (45%), Gaps = 13/158 (8%)

Query: 20  ELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLA----LLKQIQEAYGKC 75
           ELQ   Q +  L Q  + LK E+D+L     SS R+   E  L      L +++E   + 
Sbjct: 275 ELQHRNQALTSLAQEAQALKDEMDELR---QSSERAGQLEATLTSCRRRLGELRELRRQV 331

Query: 76  KEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKK----S 131
           ++  +     A +T ++ D+ +RR  +  A+ EA  ++ Q         + K +K     
Sbjct: 332 RQLEERNAGHAERTRQLEDE-LRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFEC 390

Query: 132 RTQKEKKAARARSKGK-NSDEEAPKTAQKKLKLVRTSP 168
           R  +EK  +  + K +  ++ ++ + A ++L+  +  P
Sbjct: 391 RNLEEKYESVTKEKERLLAERDSLREANEELRCAQLQP 428


>gi|154354985 hook homolog 2 isoform 1 [Homo sapiens]
          Length = 719

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 20/162 (12%)

Query: 7   LEHYLDSIENLPFELQRNFQLMRDLDQRTEDLKAE-IDKLATEYMSSARSLSSEEKLALL 65
           LE +L  +     ELQR  + + +L+  T+   A  I++L             ++K A L
Sbjct: 543 LEEHLQKLHEADLELQRKREYIEELEPPTDSSTARRIEELQHNL---------QKKDADL 593

Query: 66  KQIQEAYGKCKEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSS 125
           + ++E Y +      DK ++ MQT E   +       +L      L+E+ +     +   
Sbjct: 594 RAMEERYRRYV----DKARMVMQTMEPKQRPAAGAPPELHSLRTQLRERDVRIRHLEMDF 649

Query: 126 SKGKKSRTQKEKKAARA------RSKGKNSDEEAPKTAQKKL 161
            K +  R Q+EK    A        + +  +E AP  AQ  L
Sbjct: 650 EKSRSQREQEEKLLISAWYNMGMALQQRAGEERAPAHAQSFL 691



 Score = 31.6 bits (70), Expect = 0.67
 Identities = 36/158 (22%), Positives = 72/158 (45%), Gaps = 13/158 (8%)

Query: 20  ELQRNFQLMRDLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLA----LLKQIQEAYGKC 75
           ELQ   Q +  L Q  + LK E+D+L     SS R+   E  L      L +++E   + 
Sbjct: 275 ELQHRNQALTSLAQEAQALKDEMDELR---QSSERAGQLEATLTSCRRRLGELRELRRQV 331

Query: 76  KEFGDDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKK----S 131
           ++  +     A +T ++ D+ +RR  +  A+ EA  ++ Q         + K +K     
Sbjct: 332 RQLEERNAGHAERTRQLEDE-LRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFEC 390

Query: 132 RTQKEKKAARARSKGK-NSDEEAPKTAQKKLKLVRTSP 168
           R  +EK  +  + K +  ++ ++ + A ++L+  +  P
Sbjct: 391 RNLEEKYESVTKEKERLLAERDSLREANEELRCAQLQP 428


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,243,899
Number of Sequences: 37866
Number of extensions: 414234
Number of successful extensions: 4048
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 143
Number of HSP's successfully gapped in prelim test: 333
Number of HSP's that attempted gapping in prelim test: 3123
Number of HSP's gapped (non-prelim): 1154
length of query: 248
length of database: 18,247,518
effective HSP length: 100
effective length of query: 148
effective length of database: 14,460,918
effective search space: 2140215864
effective search space used: 2140215864
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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