Search of human proteins with 38016957

Search of human proteins with 38016957

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38016957 ras homolog gene family, member F [Homo sapiens]
         (211 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38016957 ras homolog gene family, member F [Homo sapiens]          426   e-120
gi|7656900 ras homolog D [Homo sapiens]                               227   6e-60
gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo sapi...   197   4e-51
gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Ra...   196   2e-50
gi|10835049 ras homolog gene family, member A [Homo sapiens]          192   1e-49
gi|111494251 ras homolog gene family, member C precursor [Homo s...   192   2e-49
gi|111494248 ras homolog gene family, member C precursor [Homo s...   192   2e-49
gi|28395033 ras homolog gene family, member C precursor [Homo sa...   192   2e-49
gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho famil...   187   6e-48
gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Ra...   184   5e-47
gi|50263042 ras-like protein TC10 [Homo sapiens]                      183   8e-47
gi|4757764 ras homolog gene family, member B [Homo sapiens]           183   1e-46
gi|46249393 ras homolog gene family, member G [Homo sapiens]          182   2e-46
gi|16903164 ras homolog gene family, member J [Homo sapiens]          179   2e-45
gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]           177   8e-45
gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]           175   2e-44
gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]            175   2e-44
gi|4885069 ras homolog gene family, member E [Homo sapiens]           169   1e-42
gi|4885581 Rho family GTPase 2 [Homo sapiens]                         164   5e-41
gi|11034843 ras homolog gene family, member U [Homo sapiens]          157   8e-39
gi|7657514 GTP-binding protein RHO6 [Homo sapiens]                    152   2e-37
gi|229577148 ras homolog gene family, member V [Homo sapiens]         140   8e-34
gi|4757770 ras homolog gene family, member H [Homo sapiens]           120   6e-28
gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform...    84   7e-17
gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo...    84   1e-16
gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo...    84   1e-16
gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo...    84   1e-16
gi|28376635 RAB37, member RAS oncogene family isoform 3 [Homo sa...    84   1e-16
gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]        84   1e-16
gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens]        83   1e-16

>gi|38016957 ras homolog gene family, member F [Homo sapiens]
          Length = 211

 Score =  426 bits (1094), Expect = e-120
 Identities = 211/211 (100%), Positives = 211/211 (100%)

Query: 1   MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASV 60
           MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASV
Sbjct: 1   MDAPGALAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASV 60

Query: 61  TVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHF 120
           TVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHF
Sbjct: 61  TVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHF 120

Query: 121 CRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN 180
           CRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN
Sbjct: 121 CRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN 180

Query: 181 VEDVFREAAKVALSALKKAQRQKKRRLCLLL 211
           VEDVFREAAKVALSALKKAQRQKKRRLCLLL
Sbjct: 181 VEDVFREAAKVALSALKKAQRQKKRRLCLLL 211


>gi|7656900 ras homolog D [Homo sapiens]
          Length = 210

 Score =  227 bits (578), Expect = 6e-60
 Identities = 99/181 (54%), Positives = 139/181 (76%)

Query: 15  PGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDT 74
           PG + +K+V+VGDGGCGKTSLLMV++ G+FPE Y P+VFE+Y  ++ V  K V L+++DT
Sbjct: 13  PGVRSVKVVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERYMVNLQVKGKPVHLHIWDT 72

Query: 75  AGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTD 134
           AGQ+DYDRLRPL Y +  ++L+C+DV +P S+DN+  +W+PEV HFC+ +P++++GCKTD
Sbjct: 73  AGQDDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFCKKVPIIVVGCKTD 132

Query: 135 LRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALS 194
           LRKDK  + KLR   LEP+TY +G      + A  YLECSA+  +NV  VF+EAA+VALS
Sbjct: 133 LRKDKSLVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLHDNVHAVFQEAAEVALS 192

Query: 195 A 195
           +
Sbjct: 193 S 193


>gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo
           sapiens]
          Length = 192

 Score =  197 bits (502), Expect = 4e-51
 Identities = 97/191 (50%), Positives = 130/191 (68%), Gaps = 2/191 (1%)

Query: 20  LKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQED 79
           +K V+VGDG  GKT LL+ Y+  +FP  Y P+VF+ Y+A+V V SK V L L+DTAGQED
Sbjct: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQED 63

Query: 80  YDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDK 139
           YDRLRPLSY  T + LIC+ +++P SY+NV  KWFPEV H C   P++L+G K DLR DK
Sbjct: 64  YDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDK 123

Query: 140 EQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSALKKA 199
           + + KL+  +L PITY QGL+  ++I +  YLECSA  +  ++ VF EA +  L    + 
Sbjct: 124 DTIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVL--CPQP 181

Query: 200 QRQKKRRLCLL 210
            RQ+KR   LL
Sbjct: 182 TRQQKRACSLL 192


>gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Rac1
           [Homo sapiens]
          Length = 192

 Score =  196 bits (497), Expect = 2e-50
 Identities = 95/192 (49%), Positives = 130/192 (67%), Gaps = 3/192 (1%)

Query: 20  LKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQED 79
           +K V+VGDG  GKT LL+ Y+  +FP  Y P+VF+ Y+A+V V  K V L L+DTAGQED
Sbjct: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQED 63

Query: 80  YDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDK 139
           YDRLRPLSY  T + LIC+ +++P S++NV  KW+PEV H C   P++L+G K DLR DK
Sbjct: 64  YDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDK 123

Query: 140 EQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSALKKA 199
           + + KL+  +L PITY QGL+  ++I A  YLECSA  +  ++ VF EA +  L      
Sbjct: 124 DTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLC---PP 180

Query: 200 QRQKKRRLCLLL 211
             +K++R CLLL
Sbjct: 181 PVKKRKRKCLLL 192


>gi|10835049 ras homolog gene family, member A [Homo sapiens]
          Length = 193

 Score =  192 bits (489), Expect = 1e-49
 Identities = 94/191 (49%), Positives = 130/191 (68%), Gaps = 4/191 (2%)

Query: 21  KIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQEDY 80
           K+VIVGDG CGKT LL+V+S+  FPE Y P+VFE Y A + V  K+V L L+DTAGQEDY
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66

Query: 81  DRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDKE 140
           DRLRPLSY +T ++L+C+ + +P S +N+  KW PEV HFC  +P++L+G K DLR D+ 
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEH 126

Query: 141 QLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSALKKAQ 200
             R+L   + EP+   +G     +I A  Y+ECSAK ++ V +VF  A + AL    +A+
Sbjct: 127 TRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAAL----QAR 182

Query: 201 RQKKRRLCLLL 211
           R KK+  CL+L
Sbjct: 183 RGKKKSGCLVL 193


>gi|111494251 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  192 bits (487), Expect = 2e-49
 Identities = 93/191 (48%), Positives = 129/191 (67%), Gaps = 4/191 (2%)

Query: 21  KIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQEDY 80
           K+VIVGDG CGKT LL+V+S+  FPE Y P+VFE Y A + V  K+V L L+DTAGQEDY
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66

Query: 81  DRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDKE 140
           DRLRPLSY +T ++L+C+ + +P S +N+  KW PEV HFC  +P++L+G K DLR+D+ 
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEH 126

Query: 141 QLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSALKKAQ 200
             R+L   + EP+   +G     +I A  YLECSAK +E V +VF  A +  L    + +
Sbjct: 127 TRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGL----QVR 182

Query: 201 RQKKRRLCLLL 211
           + K+RR C +L
Sbjct: 183 KNKRRRGCPIL 193


>gi|111494248 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  192 bits (487), Expect = 2e-49
 Identities = 93/191 (48%), Positives = 129/191 (67%), Gaps = 4/191 (2%)

Query: 21  KIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQEDY 80
           K+VIVGDG CGKT LL+V+S+  FPE Y P+VFE Y A + V  K+V L L+DTAGQEDY
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66

Query: 81  DRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDKE 140
           DRLRPLSY +T ++L+C+ + +P S +N+  KW PEV HFC  +P++L+G K DLR+D+ 
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEH 126

Query: 141 QLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSALKKAQ 200
             R+L   + EP+   +G     +I A  YLECSAK +E V +VF  A +  L    + +
Sbjct: 127 TRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGL----QVR 182

Query: 201 RQKKRRLCLLL 211
           + K+RR C +L
Sbjct: 183 KNKRRRGCPIL 193


>gi|28395033 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  192 bits (487), Expect = 2e-49
 Identities = 93/191 (48%), Positives = 129/191 (67%), Gaps = 4/191 (2%)

Query: 21  KIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQEDY 80
           K+VIVGDG CGKT LL+V+S+  FPE Y P+VFE Y A + V  K+V L L+DTAGQEDY
Sbjct: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDTAGQEDY 66

Query: 81  DRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDKE 140
           DRLRPLSY +T ++L+C+ + +P S +N+  KW PEV HFC  +P++L+G K DLR+D+ 
Sbjct: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRQDEH 126

Query: 141 QLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSALKKAQ 200
             R+L   + EP+   +G     +I A  YLECSAK +E V +VF  A +  L    + +
Sbjct: 127 TRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGL----QVR 182

Query: 201 RQKKRRLCLLL 211
           + K+RR C +L
Sbjct: 183 KNKRRRGCPIL 193


>gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho family,
           small GTP binding protein Rac3) [Homo sapiens]
          Length = 192

 Score =  187 bits (475), Expect = 6e-48
 Identities = 88/174 (50%), Positives = 120/174 (68%)

Query: 20  LKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQED 79
           +K V+VGDG  GKT LL+ Y+  +FP  Y P+VF+ Y+A+V V  K V L L+DTAGQED
Sbjct: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQED 63

Query: 80  YDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDK 139
           YDRLRPLSY  T + LIC+ +++P S++NV  KW+PEV H C   P++L+G K DLR DK
Sbjct: 64  YDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLRDDK 123

Query: 140 EQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVAL 193
           + + +LR  +L PITY QGL+   +I +  YLECSA  +  ++ VF EA +  L
Sbjct: 124 DTIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVL 177


>gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Rac1b
           [Homo sapiens]
          Length = 211

 Score =  184 bits (467), Expect = 5e-47
 Identities = 95/211 (45%), Positives = 130/211 (61%), Gaps = 22/211 (10%)

Query: 20  LKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQED 79
           +K V+VGDG  GKT LL+ Y+  +FP  Y P+VF+ Y+A+V V  K V L L+DTAGQED
Sbjct: 4   IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQED 63

Query: 80  YDRLRPLSYQNT-------------------HLVLICYDVMNPTSYDNVLIKWFPEVTHF 120
           YDRLRPLSY  T                    + LIC+ +++P S++NV  KW+PEV H 
Sbjct: 64  YDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHH 123

Query: 121 CRGIPMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN 180
           C   P++L+G K DLR DK+ + KL+  +L PITY QGL+  ++I A  YLECSA  +  
Sbjct: 124 CPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRG 183

Query: 181 VEDVFREAAKVALSALKKAQRQKKRRLCLLL 211
           ++ VF EA +  L        +K++R CLLL
Sbjct: 184 LKTVFDEAIRAVLC---PPPVKKRKRKCLLL 211


>gi|50263042 ras-like protein TC10 [Homo sapiens]
          Length = 205

 Score =  183 bits (465), Expect = 8e-47
 Identities = 92/198 (46%), Positives = 124/198 (62%)

Query: 12  APGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNL 71
           A GPG   LK V+VGDG  GKT LLM Y+  +FPE Y P+VF+ Y  SVTVG K+  L L
Sbjct: 2   AHGPGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGL 61

Query: 72  YDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGC 131
           YDTAGQEDYDRLRPLSY  T + LIC+ V+NP S+ NV  +W PE+  +   +P +LIG 
Sbjct: 62  YDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGT 121

Query: 132 KTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKV 191
           + DLR D + L +L   + +PI   QG    ++I A  Y+ECSA  ++ ++ VF EA   
Sbjct: 122 QIDLRDDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIA 181

Query: 192 ALSALKKAQRQKKRRLCL 209
            L+  K   +++    C+
Sbjct: 182 ILTPKKHTVKKRIGSRCI 199


>gi|4757764 ras homolog gene family, member B [Homo sapiens]
          Length = 196

 Score =  183 bits (464), Expect = 1e-46
 Identities = 87/173 (50%), Positives = 118/173 (68%)

Query: 21  KIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQEDY 80
           K+V+VGDG CGKT LL+V+S+  FPE Y P+VFE Y A + V  K+V L L+DTAGQEDY
Sbjct: 7   KLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66

Query: 81  DRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDKE 140
           DRLRPLSY +T ++L+C+ V +P S +N+  KW PEV HFC  +P++L+  K DLR D+ 
Sbjct: 67  DRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKDLRSDEH 126

Query: 141 QLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVAL 193
              +L   + EP+    G +   +I+A  YLECSAK +E V +VF  A + AL
Sbjct: 127 VRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAAL 179


>gi|46249393 ras homolog gene family, member G [Homo sapiens]
          Length = 191

 Score =  182 bits (461), Expect = 2e-46
 Identities = 89/194 (45%), Positives = 126/194 (64%), Gaps = 4/194 (2%)

Query: 18  KELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQ 77
           + +K V+VGDG  GKT LL+ Y+  +FP+ Y P+VF+ Y+A   V  + V LNL+DTAGQ
Sbjct: 2   QSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQ 61

Query: 78  EDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRK 137
           E+YDRLR LSY  T++ +IC+ + +P SY+NV  KW PEV H C  +P++L+G K DLR 
Sbjct: 62  EEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRA 121

Query: 138 DKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSALK 197
             + LR+L+     PIT  QG +  +QI A  YLECSA  ++ V++VF EA +  L+   
Sbjct: 122 QPDTLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPTP 181

Query: 198 KAQRQKKRRLCLLL 211
                K+ R C+LL
Sbjct: 182 ----IKRGRSCILL 191


>gi|16903164 ras homolog gene family, member J [Homo sapiens]
          Length = 214

 Score =  179 bits (453), Expect = 2e-45
 Identities = 91/192 (47%), Positives = 121/192 (63%)

Query: 17  RKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAG 76
           +K LK V+VGDG  GKT LLM Y+  +FPE Y P+VF+ Y  +VTVG K+  L LYDTAG
Sbjct: 19  KKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAG 78

Query: 77  QEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLR 136
           QEDY++LRPLSY NT + LIC+ V+NP SY NV  +W PE+      +P VLIG + DLR
Sbjct: 79  QEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPHVPYVLIGTQIDLR 138

Query: 137 KDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSAL 196
            D + L +L   + +P+TY  G+   + I A  YLECSA  ++ ++ VF EA        
Sbjct: 139 DDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAILTIFHPK 198

Query: 197 KKAQRQKKRRLC 208
           KK +R  +   C
Sbjct: 199 KKKKRCSEGHSC 210


>gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]
          Length = 191

 Score =  177 bits (448), Expect = 8e-45
 Identities = 84/190 (44%), Positives = 121/190 (63%), Gaps = 3/190 (1%)

Query: 20  LKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQED 79
           +K V+VGDG  GKT LL+ Y+   FP  Y P+VF+ Y  +V +G +  TL L+DTAGQED
Sbjct: 4   IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQED 63

Query: 80  YDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDK 139
           YDRLRPLSY  T + L+C+ V++P+S++NV  KW PE+TH C   P +L+G + DLR D 
Sbjct: 64  YDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDP 123

Query: 140 EQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSALKKA 199
             + KL   + +PIT          ++A  Y+ECSA  +  +++VF EA    L+AL+  
Sbjct: 124 STIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQRGLKNVFDEA---ILAALEPP 180

Query: 200 QRQKKRRLCL 209
           + Q KR+ C+
Sbjct: 181 ETQPKRKCCI 190


>gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]
          Length = 191

 Score =  175 bits (444), Expect = 2e-44
 Identities = 85/191 (44%), Positives = 122/191 (63%), Gaps = 3/191 (1%)

Query: 20  LKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQED 79
           +K V+VGDG  GKT LL+ Y+   FP  Y P+VF+ Y  +V +G +  TL L+DTAGQED
Sbjct: 4   IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQED 63

Query: 80  YDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDK 139
           YDRLRPLSY  T + L+C+ V++P+S++NV  KW PE+TH C   P +L+G + DLR D 
Sbjct: 64  YDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDP 123

Query: 140 EQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSALKKA 199
             + KL   + +PIT          ++A  Y+ECSA  ++ +++VF EA    L+AL+  
Sbjct: 124 STIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEA---ILAALEPP 180

Query: 200 QRQKKRRLCLL 210
           + +K RR  LL
Sbjct: 181 EPKKSRRCVLL 191


>gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]
          Length = 191

 Score =  175 bits (444), Expect = 2e-44
 Identities = 85/191 (44%), Positives = 122/191 (63%), Gaps = 3/191 (1%)

Query: 20  LKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQED 79
           +K V+VGDG  GKT LL+ Y+   FP  Y P+VF+ Y  +V +G +  TL L+DTAGQED
Sbjct: 4   IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQED 63

Query: 80  YDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDK 139
           YDRLRPLSY  T + L+C+ V++P+S++NV  KW PE+TH C   P +L+G + DLR D 
Sbjct: 64  YDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDP 123

Query: 140 EQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSALKKA 199
             + KL   + +PIT          ++A  Y+ECSA  ++ +++VF EA    L+AL+  
Sbjct: 124 STIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEA---ILAALEPP 180

Query: 200 QRQKKRRLCLL 210
           + +K RR  LL
Sbjct: 181 EPKKSRRCVLL 191


>gi|4885069 ras homolog gene family, member E [Homo sapiens]
          Length = 244

 Score =  169 bits (429), Expect = 1e-42
 Identities = 85/188 (45%), Positives = 122/188 (64%), Gaps = 2/188 (1%)

Query: 21  KIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQEDY 80
           KIV+VGD  CGKT+LL V+++  FPE+Y P+VFE YTAS  + ++ + L+L+DT+G   Y
Sbjct: 25  KIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGSPYY 84

Query: 81  DRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDKE 140
           D +RPLSY ++  VLIC+D+  P + D+VL KW  E+  FC    M+L+GCK+DLR D  
Sbjct: 85  DNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRTDVS 144

Query: 141 QLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFREN-VEDVFREAAKVALSAL-KK 198
            L +L   +  P++Y QG +  +QI AA Y+ECSA   EN V D+F  A    ++   K 
Sbjct: 145 TLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACVNKTNKN 204

Query: 199 AQRQKKRR 206
            +R K +R
Sbjct: 205 VKRNKSQR 212


>gi|4885581 Rho family GTPase 2 [Homo sapiens]
          Length = 227

 Score =  164 bits (415), Expect = 5e-41
 Identities = 80/186 (43%), Positives = 120/186 (64%), Gaps = 4/186 (2%)

Query: 21  KIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQEDY 80
           KIV+VGD  CGKT+LL V+++ ++P  Y P+VFE YTAS  +  + + LN++DT+G   Y
Sbjct: 9   KIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWDTSGSSYY 68

Query: 81  DRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDKE 140
           D +RPL+Y ++  VLIC+D+  P + D+VL KW  E   FC    +VL+GCK D+R D  
Sbjct: 69  DNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDMRTDLA 128

Query: 141 QLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRE-NVEDVFREAAKVALSALKKA 199
            LR+L   +L P+T+ QG    +Q+ A  Y+ECS++  E +V DVF  A    +++L + 
Sbjct: 129 TLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVA---TVASLGRG 185

Query: 200 QRQKKR 205
            RQ +R
Sbjct: 186 HRQLRR 191


>gi|11034843 ras homolog gene family, member U [Homo sapiens]
          Length = 258

 Score =  157 bits (396), Expect = 8e-39
 Identities = 78/194 (40%), Positives = 125/194 (64%), Gaps = 1/194 (0%)

Query: 12  APGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNL 71
           A G   + +K V+VGDG  GKTSL++ Y+   +P  Y P+ F+ ++A V+V  + V L L
Sbjct: 42  AGGAEGRGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQL 101

Query: 72  YDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGC 131
            DTAGQ+++D+LRPL Y NT + L+C+ V++P+S+ NV  KW PE+   C   P++L+G 
Sbjct: 102 CDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGT 161

Query: 132 KTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKV 191
           ++DLR+D + L +L   + +P+         E+I+AA Y+ECSA  ++N+++VF +AA V
Sbjct: 162 QSDLREDVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVF-DAAIV 220

Query: 192 ALSALKKAQRQKKR 205
           A       Q+Q K+
Sbjct: 221 AGIQYSDTQQQPKK 234


>gi|7657514 GTP-binding protein RHO6 [Homo sapiens]
          Length = 232

 Score =  152 bits (385), Expect = 2e-37
 Identities = 76/189 (40%), Positives = 116/189 (61%), Gaps = 1/189 (0%)

Query: 7   LAQTAAPGPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKE 66
           + +  AP P     K+V+VGD  CGKT++L V ++  +PE Y P+VFE YTA +    + 
Sbjct: 1   MKERRAPQPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQR 60

Query: 67  VTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPM 126
           V L+L+DT+G   YD +RPL Y ++  VL+C+D+  P + D+ L KW  E+  +C    +
Sbjct: 61  VELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRV 120

Query: 127 VLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRE-NVEDVF 185
           +LIGCKTDLR D   L +L   +  PI+Y QG +  +Q+ A +YLE SA   E ++  +F
Sbjct: 121 LLIGCKTDLRTDLSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIF 180

Query: 186 REAAKVALS 194
           R A+ + L+
Sbjct: 181 RTASMLCLN 189


>gi|229577148 ras homolog gene family, member V [Homo sapiens]
          Length = 236

 Score =  140 bits (353), Expect = 8e-34
 Identities = 80/209 (38%), Positives = 119/209 (56%), Gaps = 9/209 (4%)

Query: 2   DAPGALAQTAAP----GPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYT 57
           + P   A T  P     P    +K V+VGDG  GK+SL++ Y+   +P  Y P+  + ++
Sbjct: 10  EPPPLRAPTPPPRRRSAPPELGIKCVLVGDGAVGKSSLIVSYTCNGYPARYRPTALDTFS 69

Query: 58  ASVTVGSKEVTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEV 117
             V V    V + L+DTAGQED+DRLR L Y +T + L C+ V+ P+S+ N+  KW PE+
Sbjct: 70  VQVLVDGAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEI 129

Query: 118 THFCRGIPMVLIGCKTDLRKDKEQLRKLRAAQLE-PITYMQGLSACEQIRAALYLECSAK 176
                  P++L+G + DLR D   L +L     E P+   Q     E+IRA  YLECSA 
Sbjct: 130 RTHNPQAPVLLVGTQADLRDDVNVLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSAL 189

Query: 177 FRENVEDVFREAAKVALSALK-KAQRQKK 204
            ++N+++VF  A    LSA++ KA+ +KK
Sbjct: 190 TQKNLKEVFDSA---ILSAIEHKARLEKK 215


>gi|4757770 ras homolog gene family, member H [Homo sapiens]
          Length = 191

 Score =  120 bits (302), Expect = 6e-28
 Identities = 66/188 (35%), Positives = 107/188 (56%), Gaps = 10/188 (5%)

Query: 20  LKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQED 79
           +K V+VGD   GKTSLL+ ++  +FPE Y P+V+E     V +   +++L L+DTAG + 
Sbjct: 5   IKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTAGNDA 64

Query: 80  YDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDK 139
           +  +RPLSYQ   +VL+CY V N  S+ N+  KW  E+       P++++  +TD     
Sbjct: 65  FRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTD----- 119

Query: 140 EQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSALKKA 199
              R++   +   +  M+G    + +RA  YLECSA     V+ VF  A +   +A+ +A
Sbjct: 120 --QREMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVR---TAVNQA 174

Query: 200 QRQKKRRL 207
           +R+ +RRL
Sbjct: 175 RRRNRRRL 182


>gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform a
           [Homo sapiens]
          Length = 204

 Score = 84.3 bits (207), Expect = 7e-17
 Identities = 57/199 (28%), Positives = 95/199 (47%), Gaps = 34/199 (17%)

Query: 14  GPGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYD 73
           G G+++ ++V+VG GG GK++L + + Q  F   Y P++ + YT    +  +   L++ D
Sbjct: 9   GSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDILD 68

Query: 74  TAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGI--------- 124
           TAGQE++  +R    +     L+ + V +  S        F E+  F R I         
Sbjct: 69  TAGQEEFGAMREQYMRTGEGFLLVFSVTDRGS--------FEEIYKFQRQILRVKDRDEF 120

Query: 125 PMVLIGCKTDLRKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDV 184
           PM+LIG K DL   ++            +T  +G     Q++   Y+E SAK R NV+  
Sbjct: 121 PMILIGNKADLDHQRQ------------VTQEEGQQLARQLKVT-YMEASAKIRMNVDQA 167

Query: 185 FREAAKVALSALKKAQRQK 203
           F E  +V    ++K Q Q+
Sbjct: 168 FHELVRV----IRKFQEQE 182


>gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo
           sapiens]
          Length = 727

 Score = 83.6 bits (205), Expect = 1e-16
 Identities = 59/209 (28%), Positives = 100/209 (47%), Gaps = 26/209 (12%)

Query: 15  PGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHY------APSVF--EKYTASVTVGSKE 66
           P  + +K V+VGD   GKT L+   +  +    Y       P+V+  ++Y     V  + 
Sbjct: 10  PNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERS 69

Query: 67  --------VTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVT 118
                   V+L L+DT G  D+ + R  +Y  + +V++C+ + NP S  +V   W+PE+ 
Sbjct: 70  RDVVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIK 127

Query: 119 HFCRGIPMVLIGCKTDLR-KDKEQLRKLRAAQLEPITYMQ------GLSACEQIRAALYL 171
           HFC   P++L+GC+ DLR  D E + + R     PI   +      G    +++    Y 
Sbjct: 128 HFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYY 186

Query: 172 ECSAKFRENVEDVFREAAKVALSALKKAQ 200
           E S   +  ++DVF  A + AL + +  Q
Sbjct: 187 ETSVVAQFGIKDVFDNAIRAALISRRHLQ 215


>gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 734

 Score = 83.6 bits (205), Expect = 1e-16
 Identities = 59/209 (28%), Positives = 100/209 (47%), Gaps = 26/209 (12%)

Query: 15  PGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHY------APSVF--EKYTASVTVGSKE 66
           P  + +K V+VGD   GKT L+   +  +    Y       P+V+  ++Y     V  + 
Sbjct: 17  PNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERS 76

Query: 67  --------VTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVT 118
                   V+L L+DT G  D+ + R  +Y  + +V++C+ + NP S  +V   W+PE+ 
Sbjct: 77  RDVVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIK 134

Query: 119 HFCRGIPMVLIGCKTDLR-KDKEQLRKLRAAQLEPITYMQ------GLSACEQIRAALYL 171
           HFC   P++L+GC+ DLR  D E + + R     PI   +      G    +++    Y 
Sbjct: 135 HFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYY 193

Query: 172 ECSAKFRENVEDVFREAAKVALSALKKAQ 200
           E S   +  ++DVF  A + AL + +  Q
Sbjct: 194 ETSVVAQFGIKDVFDNAIRAALISRRHLQ 222


>gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo
           sapiens]
          Length = 749

 Score = 83.6 bits (205), Expect = 1e-16
 Identities = 59/209 (28%), Positives = 100/209 (47%), Gaps = 26/209 (12%)

Query: 15  PGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHY------APSVF--EKYTASVTVGSKE 66
           P  + +K V+VGD   GKT L+   +  +    Y       P+V+  ++Y     V  + 
Sbjct: 32  PNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERS 91

Query: 67  --------VTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVT 118
                   V+L L+DT G  D+ + R  +Y  + +V++C+ + NP S  +V   W+PE+ 
Sbjct: 92  RDVVDDVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIK 149

Query: 119 HFCRGIPMVLIGCKTDLR-KDKEQLRKLRAAQLEPITYMQ------GLSACEQIRAALYL 171
           HFC   P++L+GC+ DLR  D E + + R     PI   +      G    +++    Y 
Sbjct: 150 HFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKEL-GIPYY 208

Query: 172 ECSAKFRENVEDVFREAAKVALSALKKAQ 200
           E S   +  ++DVF  A + AL + +  Q
Sbjct: 209 ETSVVAQFGIKDVFDNAIRAALISRRHLQ 237


>gi|28376635 RAB37, member RAS oncogene family isoform 3 [Homo
           sapiens]
          Length = 216

 Score = 83.6 bits (205), Expect = 1e-16
 Identities = 58/173 (33%), Positives = 91/173 (52%), Gaps = 17/173 (9%)

Query: 21  KIVIVGDGGCGKTSLLMVYSQGSF-PEHYAPSVFEKYTASV-TVGSKEVTLNLYDTAGQE 78
           K ++VGD G GKTSLL+ + QG F P  ++ +V   +T  V TV    V L ++DTAGQE
Sbjct: 24  KTILVGDSGVGKTSLLVQFDQGKFIPGSFSATVGIGFTNKVVTVDGVRVKLQIWDTAGQE 83

Query: 79  DYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFC-RGIPMVLIGCKTDLRK 137
            +  +    Y++   +L+ YD+ N +S+DN+   W  E+  +  R + ++L+G K D+  
Sbjct: 84  RFRSVTHAYYRDAQALLLLYDITNKSSFDNIR-AWLTEIHEYAQRDVVIMLLGNKADMSS 142

Query: 138 DKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAK 190
           +    R +R+   E +    G+          +LE SAK   NVE  F   AK
Sbjct: 143 E----RVIRSEDGETLAREYGVP---------FLETSAKTGMNVELAFLAIAK 182


>gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]
          Length = 183

 Score = 83.6 bits (205), Expect = 1e-16
 Identities = 50/175 (28%), Positives = 94/175 (53%), Gaps = 16/175 (9%)

Query: 18  KELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQ 77
           +E K+V++G GG GK++L + +  GSF E Y P++ + Y   + V S    L + DTAG 
Sbjct: 2   REYKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGT 61

Query: 78  EDYDRLRPLSYQNTHLVLICYDVMNPTSYDNV--LIKWFPEVTHFCRGIPMVLIGCKTDL 135
           E +  +R L  +N    ++ Y ++N  S+ ++  +      V  + R +PM+L+G K DL
Sbjct: 62  EQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYER-VPMILVGNKVDL 120

Query: 136 RKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAK 190
             ++E            ++Y +G +  E+  +  ++E SAK + +V+++F E  +
Sbjct: 121 EGERE------------VSYGEGKALAEE-WSCPFMETSAKNKASVDELFAEIVR 162


>gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens]
          Length = 184

 Score = 83.2 bits (204), Expect = 1e-16
 Identities = 53/196 (27%), Positives = 97/196 (49%), Gaps = 15/196 (7%)

Query: 18  KELKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQ 77
           +E K+V++G GG GK++L + + QG F E Y P++ + Y   V V  ++  L + DTAG 
Sbjct: 2   REYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGT 61

Query: 78  EDYDRLRPLSYQNTHLVLICYDVMNPTSYDNV--LIKWFPEVTHFCRGIPMVLIGCKTDL 135
           E +  +R L  +N     + Y +   ++++++  L +    V      +PM+L+G K DL
Sbjct: 62  EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKD-TEDVPMILVGNKCDL 120

Query: 136 RKDKEQLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSA 195
             ++             +   QG +   Q     +LE SAK + NV ++F +  +     
Sbjct: 121 EDER------------VVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDLVRQINRK 168

Query: 196 LKKAQRQKKRRLCLLL 211
               +++ K++ CLLL
Sbjct: 169 TPVEKKKPKKKSCLLL 184


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,090,568
Number of Sequences: 37866
Number of extensions: 339288
Number of successful extensions: 1485
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 170
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 1081
Number of HSP's gapped (non-prelim): 243
length of query: 211
length of database: 18,247,518
effective HSP length: 98
effective length of query: 113
effective length of database: 14,536,650
effective search space: 1642641450
effective search space used: 1642641450
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.