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Search of human proteins with 37596297
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|37596297 cyclin-dependent kinase-like 1 [Homo sapiens]
(358 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|37596297 cyclin-dependent kinase-like 1 [Homo sapiens] 749 0.0
gi|57222269 cyclin-dependent kinase-like 4 [Homo sapiens] 461 e-130
gi|4505569 cyclin-dependent kinase-like 2 [Homo sapiens] 379 e-105
gi|166064027 cyclin-dependent kinase-like 3 isoform 1 [Homo sapi... 312 3e-85
gi|166064025 cyclin-dependent kinase-like 3 isoform 2 [Homo sapi... 312 3e-85
gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens] 289 2e-78
gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens] 289 2e-78
gi|4557439 cyclin-dependent kinase 3 [Homo sapiens] 239 4e-63
gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens] 227 1e-59
gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens] 224 9e-59
gi|4826675 cyclin-dependent kinase 5 [Homo sapiens] 224 1e-58
gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens] 222 4e-58
gi|4502743 cyclin-dependent kinase 7 [Homo sapiens] 204 1e-52
gi|27477122 intestinal cell kinase [Homo sapiens] 203 2e-52
gi|7662388 intestinal cell kinase [Homo sapiens] 203 2e-52
gi|11496279 male germ cell-associated kinase [Homo sapiens] 201 8e-52
gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens] 197 1e-50
gi|4502747 cyclin-dependent kinase 9 [Homo sapiens] 194 1e-49
gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens] 194 1e-49
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 194 1e-49
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 194 1e-49
gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens] 193 2e-49
gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens] 193 2e-49
gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens] 193 2e-49
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 192 3e-49
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 192 3e-49
gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens] 192 4e-49
gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens] 192 4e-49
gi|223718134 cyclin-dependent kinase 6 [Homo sapiens] 188 6e-48
gi|4502741 cyclin-dependent kinase 6 [Homo sapiens] 188 6e-48
>gi|37596297 cyclin-dependent kinase-like 1 [Homo sapiens]
Length = 358
Score = 749 bits (1934), Expect = 0.0
Identities = 358/358 (100%), Positives = 358/358 (100%)
Query: 1 MMEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLK 60
MMEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLK
Sbjct: 1 MMEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLK 60
Query: 61 HPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHK 120
HPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHK
Sbjct: 61 HPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHK 120
Query: 121 HNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQY 180
HNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQY
Sbjct: 121 HNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQY 180
Query: 181 GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVK 240
GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVK
Sbjct: 181 GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVK 240
Query: 241 IPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFENIREIEDLAKE 300
IPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFENIREIEDLAKE
Sbjct: 241 IPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFENIREIEDLAKE 300
Query: 301 HNKPTRKTLRKSRKHHCFTETSKLQYLPQLTGSSILPALDNKKYYCDTKKLNYRFPNI 358
HNKPTRKTLRKSRKHHCFTETSKLQYLPQLTGSSILPALDNKKYYCDTKKLNYRFPNI
Sbjct: 301 HNKPTRKTLRKSRKHHCFTETSKLQYLPQLTGSSILPALDNKKYYCDTKKLNYRFPNI 358
>gi|57222269 cyclin-dependent kinase-like 4 [Homo sapiens]
Length = 315
Score = 461 bits (1185), Expect = e-130
Identities = 213/302 (70%), Positives = 254/302 (84%), Gaps = 1/302 (0%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
MEKYEK+ K GEGSYGVVFKCRN+ +GQ+VA+KKF+ESEDDPV+KKIALREIRMLKQLKH
Sbjct: 1 MEKYEKLAKTGEGSYGVVFKCRNKTSGQVVAVKKFVESEDDPVVKKIALREIRMLKQLKH 60
Query: 62 PNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKH 121
PNLVNL+EVFRRKR++HLVFEYCDHT+L+EL+R GV + ++KS+ WQTLQA+NFCH H
Sbjct: 61 PNLVNLIEVFRRKRKMHLVFEYCDHTLLNELERNPNGVADGVIKSVLWQTLQALNFCHIH 120
Query: 122 NCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYG 181
NCIHRD+KPENILITK +IK+CDFGFA++L P D YTDYVATRWYR+PELLVGDTQYG
Sbjct: 121 NCIHRDIKPENILITKQGIIKICDFGFAQILI-PGDAYTDYVATRWYRAPELLVGDTQYG 179
Query: 182 PPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKI 241
VD+WAIGCVFAELL+G PLWPGKSDVDQLYLI +TLG LIPRHQ +F +N +F G+ I
Sbjct: 180 SSVDIWAIGCVFAELLTGQPLWPGKSDVDQLYLIIRTLGKLIPRHQSIFKSNGFFHGISI 239
Query: 242 PDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFENIREIEDLAKEH 301
P+PEDME LE KF ++ AL +KGCL M+P RLTC QLL YF++ +E + K
Sbjct: 240 PEPEDMETLEEKFSDVHPVALNFMKGCLKMNPDDRLTCSQLLESSYFDSFQEAQIKRKAR 299
Query: 302 NK 303
N+
Sbjct: 300 NE 301
>gi|4505569 cyclin-dependent kinase-like 2 [Homo sapiens]
Length = 493
Score = 379 bits (973), Expect = e-105
Identities = 172/309 (55%), Positives = 233/309 (75%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
MEKYE +G +GEGSYG+V KCRN+DTG+IVAIKKFLES+DD ++KKIA+REI++LKQL+H
Sbjct: 1 MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH 60
Query: 62 PNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKH 121
NLVNLLEV ++K+R +LVFE+ DHT+L +L+ + G+ +V+ +Q + + FCH H
Sbjct: 61 ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH 120
Query: 122 NCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYG 181
N IHRD+KPENIL+++ V+KLCDFGFAR L P + YTDYVATRWYR+PELLVGD +YG
Sbjct: 121 NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG 180
Query: 182 PPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKI 241
VDVWAIGC+ E+ G PL+PG SD+DQLY I LG+LIPRHQ++F+ N F+GV++
Sbjct: 181 KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL 240
Query: 242 PDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFENIREIEDLAKEH 301
P+ ++ EPLE ++P +S + L K CLH+DP +R C +LLHH +F+ E ++E
Sbjct: 241 PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL 300
Query: 302 NKPTRKTLR 310
+K R
Sbjct: 301 QLKVQKDAR 309
>gi|166064027 cyclin-dependent kinase-like 3 isoform 1 [Homo
sapiens]
Length = 592
Score = 312 bits (799), Expect = 3e-85
Identities = 147/299 (49%), Positives = 202/299 (67%), Gaps = 1/299 (0%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
ME YE +GK+GEGSYG V KC++++TGQIVAIK F E + V KIA+REI+ LKQ H
Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSV-NKIAMREIKFLKQFHH 59
Query: 62 PNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKH 121
NLVNL+EVFR+K+++HLVFE+ DHTVL EL Y G+ ++ +Q L+A+++ H +
Sbjct: 60 ENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSN 119
Query: 122 NCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYG 181
N IHRD+KPENIL+++ + KLCDFGFAR L P D YTDYVATRWYR+PEL++ DT YG
Sbjct: 120 NIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYG 179
Query: 182 PPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKI 241
PVD+WA+GC+ E+ +G P P SD+D L+ I +G+L P Q +FS + F+GV +
Sbjct: 180 KPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVL 239
Query: 242 PDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFENIREIEDLAKE 300
P + + K+P ++ ++ CL +DP R++ LLHH YF IE E
Sbjct: 240 PQVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPE 298
>gi|166064025 cyclin-dependent kinase-like 3 isoform 2 [Homo
sapiens]
Length = 455
Score = 312 bits (799), Expect = 3e-85
Identities = 147/299 (49%), Positives = 202/299 (67%), Gaps = 1/299 (0%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
ME YE +GK+GEGSYG V KC++++TGQIVAIK F E + V KIA+REI+ LKQ H
Sbjct: 1 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSV-NKIAMREIKFLKQFHH 59
Query: 62 PNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKH 121
NLVNL+EVFR+K+++HLVFE+ DHTVL EL Y G+ ++ +Q L+A+++ H +
Sbjct: 60 ENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSN 119
Query: 122 NCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYG 181
N IHRD+KPENIL+++ + KLCDFGFAR L P D YTDYVATRWYR+PEL++ DT YG
Sbjct: 120 NIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYG 179
Query: 182 PPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKI 241
PVD+WA+GC+ E+ +G P P SD+D L+ I +G+L P Q +FS + F+GV +
Sbjct: 180 KPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVL 239
Query: 242 PDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFENIREIEDLAKE 300
P + + K+P ++ ++ CL +DP R++ LLHH YF IE E
Sbjct: 240 PQVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPE 298
>gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens]
Length = 1030
Score = 289 bits (740), Expect = 2e-78
Identities = 144/313 (46%), Positives = 212/313 (67%), Gaps = 9/313 (2%)
Query: 1 MMEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLK 60
+M K+E +G +GEG+YGVV KCR+++T +IVAIKKF +SE++ +K+ LRE++ML+ LK
Sbjct: 9 VMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLK 68
Query: 61 HPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHK 120
N+V L E FRR+ +L+LVFEY + +L L+ GVP VKS +Q ++A+++CHK
Sbjct: 69 QENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHK 128
Query: 121 HNCIHRDVKPENILITKHSVIKLCDFGFARLLT-GPSDYYTDYVATRWYRSPELLVGDTQ 179
++ +HRD+KPEN+LI+ + V+KLCDFGFAR L+ G + YT+YVATRWYRSPELL+G
Sbjct: 129 NDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLG-AP 187
Query: 180 YGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGV 239
YG VD+W++GC+ EL G PL+PG+S++DQL+ I+K LG L ++F +N F G+
Sbjct: 188 YGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGL 247
Query: 240 KIPDPEDMEPLELKFPNI-SYPALGLLKGCLHMDPTQRLTCEQLLHHPYFENIREIEDLA 298
+ P + LE ++ I + L L+K L +DP R EQ L+HP F+ R ++
Sbjct: 248 RFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLD--- 304
Query: 299 KEHNKPTRKTLRK 311
P+R RK
Sbjct: 305 ---RSPSRSAKRK 314
>gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens]
Length = 1030
Score = 289 bits (740), Expect = 2e-78
Identities = 144/313 (46%), Positives = 212/313 (67%), Gaps = 9/313 (2%)
Query: 1 MMEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLK 60
+M K+E +G +GEG+YGVV KCR+++T +IVAIKKF +SE++ +K+ LRE++ML+ LK
Sbjct: 9 VMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLK 68
Query: 61 HPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHK 120
N+V L E FRR+ +L+LVFEY + +L L+ GVP VKS +Q ++A+++CHK
Sbjct: 69 QENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHK 128
Query: 121 HNCIHRDVKPENILITKHSVIKLCDFGFARLLT-GPSDYYTDYVATRWYRSPELLVGDTQ 179
++ +HRD+KPEN+LI+ + V+KLCDFGFAR L+ G + YT+YVATRWYRSPELL+G
Sbjct: 129 NDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLG-AP 187
Query: 180 YGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGV 239
YG VD+W++GC+ EL G PL+PG+S++DQL+ I+K LG L ++F +N F G+
Sbjct: 188 YGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGL 247
Query: 240 KIPDPEDMEPLELKFPNI-SYPALGLLKGCLHMDPTQRLTCEQLLHHPYFENIREIEDLA 298
+ P + LE ++ I + L L+K L +DP R EQ L+HP F+ R ++
Sbjct: 248 RFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLD--- 304
Query: 299 KEHNKPTRKTLRK 311
P+R RK
Sbjct: 305 ---RSPSRSAKRK 314
>gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]
Length = 305
Score = 239 bits (609), Expect = 4e-63
Identities = 126/296 (42%), Positives = 181/296 (61%), Gaps = 15/296 (5%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
M+ ++K+ KIGEG+YGVV+K +NR+TGQ+VA+KK + + A+REI +LK+LKH
Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
Query: 62 PNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRG-VPEHLVKSITWQTLQAVNFCHK 120
PN+V LL+V +R+L+LVFE+ + +D +P HL+KS +Q LQ V+FCH
Sbjct: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
Query: 121 HNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQY 180
H IHRD+KP+N+LI + IKL DFG AR P YT V T WYR+PE+L+G Y
Sbjct: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
Query: 181 GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVK 240
VD+W+IGC+FAE+++ L+PG S++DQL+ I + LG S + + +
Sbjct: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLG--------TPSEDTWPGVTQ 232
Query: 241 IPDPEDMEP------LELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFEN 290
+PD + P LE PN+ LL L DP+QR+T + L HPYF +
Sbjct: 233 LPDYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS 288
>gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]
Length = 298
Score = 227 bits (579), Expect = 1e-59
Identities = 121/303 (39%), Positives = 177/303 (58%), Gaps = 27/303 (8%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
ME ++K+ KIGEG+YGVV+K RN+ TG++VA+KK + + A+REI +LK+L H
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 62 PNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQ-RGVPEHLVKSITWQTLQAVNFCHK 120
PN+V LL+V + +L+LVFE+ + +D G+P L+KS +Q LQ + FCH
Sbjct: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
Query: 121 HNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQY 180
H +HRD+KP+N+LI IKL DFG AR P YT V T WYR+PE+L+G Y
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
Query: 181 GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLG----------DLIPRHQQVF 230
VD+W++GC+FAE+++ L+PG S++DQL+ I +TLG +P ++ F
Sbjct: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF 240
Query: 231 S--TNQYFSGVKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYF 288
Q FS V P ED LL LH DP +R++ + L HP+F
Sbjct: 241 PKWARQDFSKVVPPLDED--------------GRSLLSQMLHYDPNKRISAKAALAHPFF 286
Query: 289 ENI 291
+++
Sbjct: 287 QDV 289
>gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]
Length = 297
Score = 224 bits (571), Expect = 9e-59
Identities = 127/305 (41%), Positives = 180/305 (59%), Gaps = 30/305 (9%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKF-LESEDDPVIKKIALREIRMLKQLK 60
ME Y KI KIGEG+YGVV+K R++ TGQ+VA+KK LESE++ V A+REI +LK+L+
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGV-PSTAIREISLLKELR 59
Query: 61 HPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRG--VPEHLVKSITWQTLQAVNFC 118
HPN+V+L +V + RL+L+FE+ + LD G + LVKS +Q LQ + FC
Sbjct: 60 HPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
Query: 119 HKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDT 178
H +HRD+KP+N+LI IKL DFG AR P YT V T WYRSPE+L+G
Sbjct: 120 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSA 179
Query: 179 QYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSG 238
+Y PVD+W+IG +FAEL + PL+ G S++DQL+ I + LG N+ +
Sbjct: 180 RYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGT---------PNNEVW-- 228
Query: 239 VKIPDPEDMEPLELKFP------------NISYPALGLLKGCLHMDPTQRLTCEQLLHHP 286
P+ E ++ + FP N+ L LL L DP +R++ + L+HP
Sbjct: 229 ---PEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHP 285
Query: 287 YFENI 291
YF ++
Sbjct: 286 YFNDL 290
>gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]
Length = 292
Score = 224 bits (570), Expect = 1e-58
Identities = 121/296 (40%), Positives = 172/296 (58%), Gaps = 15/296 (5%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
M+KYEK+ KIGEG+YG VFK +NR+T +IVA+K+ +DD + ALREI +LK+LKH
Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 62 PNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKH 121
N+V L +V ++L LVFE+CD + D + +VKS +Q L+ + FCH
Sbjct: 61 KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120
Query: 122 NCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYG 181
N +HRD+KP+N+LI ++ +KL DFG AR P Y+ V T WYR P++L G Y
Sbjct: 121 NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS 180
Query: 182 PPVDVWAIGCVFAELL-SGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVK 240
+D+W+ GC+FAEL +G PL+PG DQL I + LG + Q+ S K
Sbjct: 181 TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLG--------TPTEEQWPSMTK 232
Query: 241 IPD--PEDMEPLELKF----PNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFEN 290
+PD P M P P ++ LL+ L +P QR++ E+ L HPYF +
Sbjct: 233 LPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
>gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]
Length = 297
Score = 222 bits (566), Expect = 4e-58
Identities = 126/305 (41%), Positives = 179/305 (58%), Gaps = 30/305 (9%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKF-LESEDDPVIKKIALREIRMLKQLK 60
ME Y KI KIGEG+YGVV+K R++ TGQ+VA+KK LESE++ V A+REI +LK+L+
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGV-PSTAIREISLLKELR 59
Query: 61 HPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRG--VPEHLVKSITWQTLQAVNFC 118
HPN+V+L +V + RL+L+FE+ + LD G + LVKS +Q LQ + FC
Sbjct: 60 HPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
Query: 119 HKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDT 178
H +HRD+KP+N+LI IKL DFG AR P YT T WYRSPE+L+G
Sbjct: 120 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSA 179
Query: 179 QYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSG 238
+Y PVD+W+IG +FAEL + PL+ G S++DQL+ I + LG N+ +
Sbjct: 180 RYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGT---------PNNEVW-- 228
Query: 239 VKIPDPEDMEPLELKFP------------NISYPALGLLKGCLHMDPTQRLTCEQLLHHP 286
P+ E ++ + FP N+ L LL L DP +R++ + L+HP
Sbjct: 229 ---PEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHP 285
Query: 287 YFENI 291
YF ++
Sbjct: 286 YFNDL 290
>gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]
Length = 346
Score = 204 bits (519), Expect = 1e-52
Identities = 120/296 (40%), Positives = 170/296 (57%), Gaps = 16/296 (5%)
Query: 3 EKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFL---ESEDDPVIKKIALREIRMLKQL 59
++YEK+ +GEG + V+K R+++T QIVAIKK SE I + ALREI++L++L
Sbjct: 10 KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69
Query: 60 KHPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGV--PEHLVKSITWQTLQAVNF 117
HPN++ LL+ F K + LVF++ + T L + + V P H +K+ TLQ + +
Sbjct: 70 SHPNIIGLLDAFGHKSNISLVFDFME-TDLEVIIKDNSLVLTPSH-IKAYMLMTLQGLEY 127
Query: 118 CHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGD 177
H+H +HRD+KP N+L+ ++ V+KL DFG A+ P+ YT V TRWYR+PELL G
Sbjct: 128 LHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGA 187
Query: 178 TQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQ---VFSTNQ 234
YG VD+WA+GC+ AELL VP PG SD+DQL I +TLG P +Q + S
Sbjct: 188 RMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLG--TPTEEQWPDMCSLPD 245
Query: 235 YFSGVKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFEN 290
Y + P PL F L L++G +P R+T Q L YF N
Sbjct: 246 YVTFKSFPG----IPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSN 297
>gi|27477122 intestinal cell kinase [Homo sapiens]
Length = 632
Score = 203 bits (517), Expect = 2e-52
Identities = 109/289 (37%), Positives = 170/289 (58%), Gaps = 5/289 (1%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
M +Y I ++G+G+YG V R+ ++G+++AIKK ++ + + + LRE++ LK+L H
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKK-MKRKFYSWEECMNLREVKSLKKLNH 59
Query: 62 PNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKH 121
N+V L EV R L+ +FEY + + + PE +++I +Q LQ + F HKH
Sbjct: 60 ANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKH 119
Query: 122 NCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYG 181
HRD+KPEN+L ++K+ DFG AR + YTDYV+TRWYR+PE+L+ T Y
Sbjct: 120 GFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPP-YTDYVSTRWYRAPEVLLRSTNYS 178
Query: 182 PPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKI 241
P+DVWA+GC+ AE+ + PL+PG S++D ++ I + LG P+ Q S +
Sbjct: 179 SPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLG--TPKKTDWPEGYQLSSAMNF 236
Query: 242 PDPEDM-EPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFE 289
P+ + L+ PN S A+ LL+ L DP +R T Q L +PYF+
Sbjct: 237 RWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQ 285
>gi|7662388 intestinal cell kinase [Homo sapiens]
Length = 632
Score = 203 bits (517), Expect = 2e-52
Identities = 109/289 (37%), Positives = 170/289 (58%), Gaps = 5/289 (1%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
M +Y I ++G+G+YG V R+ ++G+++AIKK ++ + + + LRE++ LK+L H
Sbjct: 1 MNRYTTIRQLGDGTYGSVLLGRSIESGELIAIKK-MKRKFYSWEECMNLREVKSLKKLNH 59
Query: 62 PNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKH 121
N+V L EV R L+ +FEY + + + PE +++I +Q LQ + F HKH
Sbjct: 60 ANVVKLKEVIRENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKH 119
Query: 122 NCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYG 181
HRD+KPEN+L ++K+ DFG AR + YTDYV+TRWYR+PE+L+ T Y
Sbjct: 120 GFFHRDLKPENLLCMGPELVKIADFGLAREIRSKPP-YTDYVSTRWYRAPEVLLRSTNYS 178
Query: 182 PPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKI 241
P+DVWA+GC+ AE+ + PL+PG S++D ++ I + LG P+ Q S +
Sbjct: 179 SPIDVWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLG--TPKKTDWPEGYQLSSAMNF 236
Query: 242 PDPEDM-EPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFE 289
P+ + L+ PN S A+ LL+ L DP +R T Q L +PYF+
Sbjct: 237 RWPQCVPNNLKTLIPNASSEAVQLLRDMLQWDPKKRPTASQALRYPYFQ 285
>gi|11496279 male germ cell-associated kinase [Homo sapiens]
Length = 623
Score = 201 bits (511), Expect = 8e-52
Identities = 109/290 (37%), Positives = 172/290 (59%), Gaps = 7/290 (2%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
M +Y + ++G+G+YG V ++ ++G++VAIK+ ++ + + + LRE++ LK+L H
Sbjct: 1 MNRYTTMRQLGDGTYGSVLMGKSNESGELVAIKR-MKRKFYSWDECMNLREVKSLKKLNH 59
Query: 62 PNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHKH 121
N++ L EV R L+ +FEY + + + PE ++++I +Q LQ + F HKH
Sbjct: 60 ANVIKLKEVIRENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKH 119
Query: 122 NCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQYG 181
HRD+KPEN+L ++K+ DFG AR L YTDYV+TRWYR+PE+L+ + Y
Sbjct: 120 GFFHRDMKPENLLCMGPELVKIADFGLARELRSQPP-YTDYVSTRWYRAPEVLLRSSVYS 178
Query: 182 PPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKI 241
P+DVWA+G + AEL PL+PG S+VD+++ I + LG P+ Q S +
Sbjct: 179 SPIDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLG--TPKKSDWPEGYQLASSMNF 236
Query: 242 PDPEDMEPLELK--FPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFE 289
P+ + P+ LK PN S A+ L+ L+ DP +R T Q L HPYF+
Sbjct: 237 RFPQCV-PINLKTLIPNASNEAIQLMTEMLNWDPKKRPTASQALKHPYFQ 285
>gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens]
Length = 523
Score = 197 bits (501), Expect = 1e-50
Identities = 103/291 (35%), Positives = 168/291 (57%), Gaps = 4/291 (1%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKF-LESEDDPVIKKIALREIRMLKQLK 60
ME Y K+ K+GEG+Y V+K R++ T +VA+K+ LE E+ A+RE+ +LK LK
Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCT--AIREVSLLKDLK 246
Query: 61 HPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHK 120
H N+V L ++ + L LVFEY D + +D + H VK +Q L+ + +CH+
Sbjct: 247 HANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHR 306
Query: 121 HNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQY 180
+HRD+KP+N+LI + +KL DFG AR + P+ Y++ V T WYR P++L+G ++Y
Sbjct: 307 RKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEY 366
Query: 181 GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVK 240
+D+W +GC+F E+ SG PL+PG + D+L+LI + LG S+N+ F
Sbjct: 367 STQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNYN 426
Query: 241 IPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFENI 291
P + +PL P + + L+ L + +R++ E+ + H YF ++
Sbjct: 427 FPKYKP-QPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSL 476
>gi|4502747 cyclin-dependent kinase 9 [Homo sapiens]
Length = 372
Score = 194 bits (492), Expect = 1e-49
Identities = 105/300 (35%), Positives = 166/300 (55%), Gaps = 13/300 (4%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
+ KYEK+ KIG+G++G VFK R+R TGQ VA+KK L + ALREI++L+ LKH
Sbjct: 16 VSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKH 75
Query: 62 PNLVNLLEVFRRKR--------RLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQ 113
N+VNL+E+ R K ++LVF++C+H + L +K + L
Sbjct: 76 ENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLN 135
Query: 114 AVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLT----GPSDYYTDYVATRWYR 169
+ + H++ +HRD+K N+LIT+ V+KL DFG AR + + YT+ V T WYR
Sbjct: 136 GLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYR 195
Query: 170 SPELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQV 229
PELL+G+ YGPP+D+W GC+ AE+ + P+ G ++ QL LI + G + P
Sbjct: 196 PPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPN 255
Query: 230 FSTNQYFSGVKIPDPEDMEPLELKFPNISYP-ALGLLKGCLHMDPTQRLTCEQLLHHPYF 288
+ + +++ + + + + P AL L+ L +DP QR+ + L+H +F
Sbjct: 256 VDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFF 315
>gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]
Length = 346
Score = 194 bits (492), Expect = 1e-49
Identities = 111/289 (38%), Positives = 168/289 (58%), Gaps = 3/289 (1%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLK- 60
M++Y +G+IGEG++G+VFK ++ +TG+IVA+KK + ALREI+ L++++
Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
Query: 61 HPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHK 120
+ +V L VF L FE+ + + QR + + VKS L+ V FCH
Sbjct: 61 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA 120
Query: 121 HNCIHRDVKPENILITKHSVIKLCDFGFARLLTGP-SDYYTDYVATRWYRSPELLVGDTQ 179
+N +HRD+KP N+LI+ +K+ DFG AR+ + S YT VATRWYR+PELL G Q
Sbjct: 121 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ 180
Query: 180 YGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGV 239
Y VD+W++GC+ ELL+G PL+PGK+D++QL + + LG P+ + ++ +
Sbjct: 181 YDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNKI 240
Query: 240 KIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYF 288
+ M PLE P++S AL LL L P QR+ + L H YF
Sbjct: 241 SFKEQVPM-PLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF 288
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 194 bits (492), Expect = 1e-49
Identities = 109/301 (36%), Positives = 169/301 (56%), Gaps = 12/301 (3%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
++K++ IG IGEG+YG V+K R++DTG++VA+KK + A+REI++L+QL H
Sbjct: 702 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTH 761
Query: 62 PNLVNLLEVF----------RRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQT 111
+++N+ E+ + K +LVFEY DH ++ L+ E+ +KS Q
Sbjct: 762 QSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQL 821
Query: 112 LQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTG-PSDYYTDYVATRWYRS 170
++ +++CHK N +HRD+K NIL+ IKL DFG ARL + S YT+ V T WYR
Sbjct: 822 MEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRP 881
Query: 171 PELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVF 230
PELL+G+ +Y P +DVW+ GC+ EL + P++ ++ QL LI + G P
Sbjct: 882 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDV 941
Query: 231 STNQYFSGVKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFEN 290
YF+ +K P + L +F I AL L L +DP++R T EQ L + +
Sbjct: 942 IKLPYFNTMK-PKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRD 1000
Query: 291 I 291
+
Sbjct: 1001 V 1001
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 194 bits (492), Expect = 1e-49
Identities = 109/301 (36%), Positives = 169/301 (56%), Gaps = 12/301 (3%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
++K++ IG IGEG+YG V+K R++DTG++VA+KK + A+REI++L+QL H
Sbjct: 702 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTH 761
Query: 62 PNLVNLLEVF----------RRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQT 111
+++N+ E+ + K +LVFEY DH ++ L+ E+ +KS Q
Sbjct: 762 QSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENHIKSFMRQL 821
Query: 112 LQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTG-PSDYYTDYVATRWYRS 170
++ +++CHK N +HRD+K NIL+ IKL DFG ARL + S YT+ V T WYR
Sbjct: 822 MEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRP 881
Query: 171 PELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVF 230
PELL+G+ +Y P +DVW+ GC+ EL + P++ ++ QL LI + G P
Sbjct: 882 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDV 941
Query: 231 STNQYFSGVKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFEN 290
YF+ +K P + L +F I AL L L +DP++R T EQ L + +
Sbjct: 942 IKLPYFNTMK-PKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRD 1000
Query: 291 I 291
+
Sbjct: 1001 V 1001
>gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens]
Length = 504
Score = 193 bits (491), Expect = 2e-49
Identities = 109/306 (35%), Positives = 168/306 (54%), Gaps = 16/306 (5%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKF-LESEDDPVIKKIALREIRMLKQLK 60
+E Y K+ K+GEG+Y VFK R++ T +VA+K+ LE E+ A+RE+ +LK LK
Sbjct: 171 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCT--AIREVSLLKNLK 228
Query: 61 HPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHK 120
H N+V L ++ R L LVFEY D + LD + H VK +Q L+ + +CH
Sbjct: 229 HANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHH 288
Query: 121 HNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQY 180
+HRD+KP+N+LI + +KL DFG AR + P+ Y++ V T WYR P++L+G T+Y
Sbjct: 289 RKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEY 348
Query: 181 GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLG----DLIPRHQQVFSTNQYF 236
P+D+W +GC+ E+ +G PL+PG + ++L+LI + LG + P Y
Sbjct: 349 STPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYS 408
Query: 237 SGVKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYF----ENIR 292
+P +PL P + + LL L + R++ E L H YF E +
Sbjct: 409 FPCYLP-----QPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSLGERVH 463
Query: 293 EIEDLA 298
++ED A
Sbjct: 464 QLEDTA 469
>gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
Length = 474
Score = 193 bits (491), Expect = 2e-49
Identities = 109/306 (35%), Positives = 168/306 (54%), Gaps = 16/306 (5%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKF-LESEDDPVIKKIALREIRMLKQLK 60
+E Y K+ K+GEG+Y VFK R++ T +VA+K+ LE E+ A+RE+ +LK LK
Sbjct: 141 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCT--AIREVSLLKNLK 198
Query: 61 HPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHK 120
H N+V L ++ R L LVFEY D + LD + H VK +Q L+ + +CH
Sbjct: 199 HANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHH 258
Query: 121 HNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQY 180
+HRD+KP+N+LI + +KL DFG AR + P+ Y++ V T WYR P++L+G T+Y
Sbjct: 259 RKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEY 318
Query: 181 GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLG----DLIPRHQQVFSTNQYF 236
P+D+W +GC+ E+ +G PL+PG + ++L+LI + LG + P Y
Sbjct: 319 STPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYS 378
Query: 237 SGVKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYF----ENIR 292
+P +PL P + + LL L + R++ E L H YF E +
Sbjct: 379 FPCYLP-----QPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSLGERVH 433
Query: 293 EIEDLA 298
++ED A
Sbjct: 434 QLEDTA 439
>gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
Length = 474
Score = 193 bits (491), Expect = 2e-49
Identities = 109/306 (35%), Positives = 168/306 (54%), Gaps = 16/306 (5%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKF-LESEDDPVIKKIALREIRMLKQLK 60
+E Y K+ K+GEG+Y VFK R++ T +VA+K+ LE E+ A+RE+ +LK LK
Sbjct: 141 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCT--AIREVSLLKNLK 198
Query: 61 HPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHK 120
H N+V L ++ R L LVFEY D + LD + H VK +Q L+ + +CH
Sbjct: 199 HANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHH 258
Query: 121 HNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQY 180
+HRD+KP+N+LI + +KL DFG AR + P+ Y++ V T WYR P++L+G T+Y
Sbjct: 259 RKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEY 318
Query: 181 GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLG----DLIPRHQQVFSTNQYF 236
P+D+W +GC+ E+ +G PL+PG + ++L+LI + LG + P Y
Sbjct: 319 STPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYS 378
Query: 237 SGVKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYF----ENIR 292
+P +PL P + + LL L + R++ E L H YF E +
Sbjct: 379 FPCYLP-----QPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSLGERVH 433
Query: 293 EIEDLA 298
++ED A
Sbjct: 434 QLEDTA 439
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 192 bits (489), Expect = 3e-49
Identities = 110/301 (36%), Positives = 168/301 (55%), Gaps = 12/301 (3%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
++K++ IG IGEG+YG V+K +++DTG++VA+KK + A+REI++L+QL H
Sbjct: 724 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH 783
Query: 62 PNLVNLLEVFRRKR----------RLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQT 111
++VN+ E+ K+ +LVFEY DH ++ L+ E +KS Q
Sbjct: 784 RSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQL 843
Query: 112 LQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTG-PSDYYTDYVATRWYRS 170
++ + +CHK N +HRD+K NIL+ IKL DFG ARL S YT+ V T WYR
Sbjct: 844 MEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRP 903
Query: 171 PELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVF 230
PELL+G+ +Y P +DVW+ GC+ EL + P++ ++ QL LI + G P
Sbjct: 904 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDV 963
Query: 231 STNQYFSGVKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFEN 290
YF+ +K P + L +F I AL LL L +DP++R T EQ L + ++
Sbjct: 964 IKLPYFNTMK-PKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKD 1022
Query: 291 I 291
+
Sbjct: 1023 V 1023
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 192 bits (489), Expect = 3e-49
Identities = 110/301 (36%), Positives = 168/301 (55%), Gaps = 12/301 (3%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKH 61
++K++ IG IGEG+YG V+K +++DTG++VA+KK + A+REI++L+QL H
Sbjct: 724 VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH 783
Query: 62 PNLVNLLEVFRRKR----------RLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQT 111
++VN+ E+ K+ +LVFEY DH ++ L+ E +KS Q
Sbjct: 784 RSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQL 843
Query: 112 LQAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTG-PSDYYTDYVATRWYRS 170
++ + +CHK N +HRD+K NIL+ IKL DFG ARL S YT+ V T WYR
Sbjct: 844 MEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYRP 903
Query: 171 PELLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVF 230
PELL+G+ +Y P +DVW+ GC+ EL + P++ ++ QL LI + G P
Sbjct: 904 PELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDV 963
Query: 231 STNQYFSGVKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFEN 290
YF+ +K P + L +F I AL LL L +DP++R T EQ L + ++
Sbjct: 964 IKLPYFNTMK-PKKQYRRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKD 1022
Query: 291 I 291
+
Sbjct: 1023 V 1023
>gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens]
Length = 502
Score = 192 bits (488), Expect = 4e-49
Identities = 102/293 (34%), Positives = 163/293 (55%), Gaps = 4/293 (1%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKF-LESEDDPVIKKIALREIRMLKQLK 60
+E Y K+ K+GEG+Y V+K +++ T +VA+K+ LE E+ A+RE+ +LK LK
Sbjct: 168 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCT--AIREVSLLKDLK 225
Query: 61 HPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHK 120
H N+V L ++ ++ L LVFEY D + LD + H VK +Q L+ + +CH+
Sbjct: 226 HANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHR 285
Query: 121 HNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQY 180
+HRD+KP+N+LI + +KL DFG AR + P+ Y++ V T WYR P++L+G T Y
Sbjct: 286 QKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDY 345
Query: 181 GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVK 240
+D+W +GC+F E+ +G PL+PG + +QL+ I + LG +N+ F
Sbjct: 346 STQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYN 405
Query: 241 IPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFENIRE 293
P E L P + LL L + R++ E + HP+F ++ E
Sbjct: 406 YPKYR-AEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLGE 457
>gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens]
Length = 496
Score = 192 bits (488), Expect = 4e-49
Identities = 102/293 (34%), Positives = 163/293 (55%), Gaps = 4/293 (1%)
Query: 2 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKF-LESEDDPVIKKIALREIRMLKQLK 60
+E Y K+ K+GEG+Y V+K +++ T +VA+K+ LE E+ A+RE+ +LK LK
Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHEEGAPCT--AIREVSLLKDLK 219
Query: 61 HPNLVNLLEVFRRKRRLHLVFEYCDHTVLHELDRYQRGVPEHLVKSITWQTLQAVNFCHK 120
H N+V L ++ ++ L LVFEY D + LD + H VK +Q L+ + +CH+
Sbjct: 220 HANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHR 279
Query: 121 HNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPELLVGDTQY 180
+HRD+KP+N+LI + +KL DFG AR + P+ Y++ V T WYR P++L+G T Y
Sbjct: 280 QKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDY 339
Query: 181 GPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVK 240
+D+W +GC+F E+ +G PL+PG + +QL+ I + LG +N+ F
Sbjct: 340 STQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYN 399
Query: 241 IPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYFENIRE 293
P E L P + LL L + R++ E + HP+F ++ E
Sbjct: 400 YPKYR-AEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLGE 451
>gi|223718134 cyclin-dependent kinase 6 [Homo sapiens]
Length = 326
Score = 188 bits (478), Expect = 6e-48
Identities = 112/320 (35%), Positives = 178/320 (55%), Gaps = 24/320 (7%)
Query: 3 EKYEKIGKIGEGSYGVVFKCRN-RDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLK- 60
++YE + +IGEG+YG VFK R+ ++ G+ VA+K+ + + +RE+ +L+ L+
Sbjct: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70
Query: 61 --HPNLVNLLEVFR-----RKRRLHLVFEYCDHTVLHELDRY-QRGVPEHLVKSITWQTL 112
HPN+V L +V R+ +L LVFE+ D + LD+ + GVP +K + +Q L
Sbjct: 71 FEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLL 130
Query: 113 QAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPE 172
+ ++F H H +HRD+KP+NIL+T IKL DFG AR+ + T V T WYR+PE
Sbjct: 131 RGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWYRAPE 189
Query: 173 LLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQ----Q 228
+L+ + Y PVD+W++GC+FAE+ PL+ G SDVDQL I +G +P +
Sbjct: 190 VLL-QSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIG--LPGEEDWPRD 246
Query: 229 VFSTNQYFSGVKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYF 288
V Q F + +P+E +I LL CL +P +R++ L HPYF
Sbjct: 247 VALPRQAFHS------KSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF 300
Query: 289 ENIREIEDLAKEHNKPTRKT 308
+++ ++ H P++ T
Sbjct: 301 QDLERCKENLDSHLPPSQNT 320
>gi|4502741 cyclin-dependent kinase 6 [Homo sapiens]
Length = 326
Score = 188 bits (478), Expect = 6e-48
Identities = 112/320 (35%), Positives = 178/320 (55%), Gaps = 24/320 (7%)
Query: 3 EKYEKIGKIGEGSYGVVFKCRN-RDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLK- 60
++YE + +IGEG+YG VFK R+ ++ G+ VA+K+ + + +RE+ +L+ L+
Sbjct: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70
Query: 61 --HPNLVNLLEVFR-----RKRRLHLVFEYCDHTVLHELDRY-QRGVPEHLVKSITWQTL 112
HPN+V L +V R+ +L LVFE+ D + LD+ + GVP +K + +Q L
Sbjct: 71 FEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLL 130
Query: 113 QAVNFCHKHNCIHRDVKPENILITKHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRSPE 172
+ ++F H H +HRD+KP+NIL+T IKL DFG AR+ + T V T WYR+PE
Sbjct: 131 RGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWYRAPE 189
Query: 173 LLVGDTQYGPPVDVWAIGCVFAELLSGVPLWPGKSDVDQLYLIRKTLGDLIPRHQ----Q 228
+L+ + Y PVD+W++GC+FAE+ PL+ G SDVDQL I +G +P +
Sbjct: 190 VLL-QSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIG--LPGEEDWPRD 246
Query: 229 VFSTNQYFSGVKIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLTCEQLLHHPYF 288
V Q F + +P+E +I LL CL +P +R++ L HPYF
Sbjct: 247 VALPRQAFHS------KSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF 300
Query: 289 ENIREIEDLAKEHNKPTRKT 308
+++ ++ H P++ T
Sbjct: 301 QDLERCKENLDSHLPPSQNT 320
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.141 0.440
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,697,389
Number of Sequences: 37866
Number of extensions: 682767
Number of successful extensions: 3848
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 707
Number of HSP's successfully gapped in prelim test: 80
Number of HSP's that attempted gapping in prelim test: 1361
Number of HSP's gapped (non-prelim): 1023
length of query: 358
length of database: 18,247,518
effective HSP length: 103
effective length of query: 255
effective length of database: 14,347,320
effective search space: 3658566600
effective search space used: 3658566600
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.