Guide to the Human Genome
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Search of human proteins with 37595541

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|37595541 tripartite motif-containing 69 isoform b [Homo
sapiens]
         (341 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|37595541 tripartite motif-containing 69 isoform b [Homo sapiens]   692   0.0  
gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]   689   0.0  
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   199   4e-51
gi|217035095 tripartite motif-containing 62 [Homo sapiens]            187   2e-47
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   184   8e-47
gi|31542779 tripartite motif family-like 1 [Homo sapiens]             177   9e-45
gi|63054855 erythroblast membrane-associated protein precursor [...   171   7e-43
gi|19923536 erythroblast membrane-associated protein precursor [...   171   7e-43
gi|4557743 Mediterranean fever protein [Homo sapiens]                 168   6e-42
gi|30023818 tripartite motif protein 50A [Homo sapiens]               156   2e-38
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]    154   1e-37
gi|5730009 ret finger protein [Homo sapiens]                          153   2e-37
gi|44680130 tripartite motif-containing 7 isoform 2 [Homo sapiens]    150   1e-36
gi|44680128 tripartite motif-containing 7 isoform 3 [Homo sapiens]    150   1e-36
gi|44680126 tripartite motif-containing 7 isoform 3 [Homo sapiens]    150   1e-36
gi|44680124 tripartite motif-containing 7 isoform 3 [Homo sapiens]    150   1e-36
gi|37622899 ring finger protein 137 [Homo sapiens]                    142   4e-34
gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]      142   6e-34
gi|31881693 butyrophilin, subfamily 2, member A2 isoform b [Homo...   142   6e-34
gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo ...   142   6e-34
gi|15208660 tripartite motif protein 21 [Homo sapiens]                141   7e-34
gi|22749269 ring finger protein 129 [Homo sapiens]                    140   1e-33
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            140   2e-33
gi|222418658 butyrophilin, subfamily 3, member A1 isoform c [Hom...   138   8e-33
gi|37595558 butyrophilin, subfamily 3, member A1 isoform a [Homo...   138   8e-33
gi|5921461 butyrophilin, subfamily 2, member A1 isoform 1 precur...   138   8e-33
gi|157743261 tripartite motif-containing 75 [Homo sapiens]            137   1e-32
gi|5901908 butyrophilin, subfamily 3, member A3 isoform a [Homo ...   136   3e-32
gi|37574628 butyrophilin, subfamily 3, member A3 isoform b [Homo...   136   3e-32
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             135   7e-32

>gi|37595541 tripartite motif-containing 69 isoform b [Homo sapiens]
          Length = 341

 Score =  692 bits (1787), Expect = 0.0
 Identities = 341/341 (100%), Positives = 341/341 (100%)

Query: 1   MEEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEK 60
           MEEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEK
Sbjct: 1   MEEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEK 60

Query: 61  DILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHS 120
           DILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHS
Sbjct: 61  DILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHS 120

Query: 121 LEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLS 180
           LEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLS
Sbjct: 121 LEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLS 180

Query: 181 KSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESI 240
           KSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESI
Sbjct: 181 KSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESI 240

Query: 241 IRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNA 300
           IRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNA
Sbjct: 241 IRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNA 300

Query: 301 KTMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHPQ 341
           KTMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHPQ
Sbjct: 301 KTMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHPQ 341


>gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]
          Length = 500

 Score =  689 bits (1777), Expect = 0.0
 Identities = 339/339 (100%), Positives = 339/339 (100%)

Query: 3   EELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDI 62
           EELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDI
Sbjct: 162 EELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDI 221

Query: 63  LTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLE 122
           LTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLE
Sbjct: 222 LTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLE 281

Query: 123 QGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKS 182
           QGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKS
Sbjct: 282 QGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKS 341

Query: 183 QTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIR 242
           QTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIR
Sbjct: 342 QTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIR 401

Query: 243 KGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKT 302
           KGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKT
Sbjct: 402 KGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKT 461

Query: 303 MTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHPQ 341
           MTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHPQ
Sbjct: 462 MTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHPQ 500


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  199 bits (505), Expect = 4e-51
 Identities = 119/330 (36%), Positives = 180/330 (54%), Gaps = 7/330 (2%)

Query: 12  LETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREEGK 71
           LE  L+E+   ++ +++     K      +Q +  EF +LH+ L  +++ +L+ L EE +
Sbjct: 161 LEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQ 220

Query: 72  ALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATR 131
            + + +  N + L ++      +   ++ K   Q+ F+ LKD+ + L   E+   +  T 
Sbjct: 221 DILQRLRENAAHLGDKRRDLAHLAAEVEGKC-LQSGFEMLKDVKSTLEKCEKVKTMEVTS 279

Query: 132 ELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDI 191
             I  + N   +  P QY   R++   L   ++ +TLDP+TAHPNLVLS+ + SV   + 
Sbjct: 280 VSIELEKNFSNF--PRQYFALRKILKQL---IADVTLDPETAHPNLVLSEDRKSVKFVET 334

Query: 192 K-KIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTP 250
           + + +PD P RF     VL + GFTSG+ YWEVEV  KT W VGV R+S+ RKG     P
Sbjct: 335 RLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPLP 394

Query: 251 EQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFS 310
           E G+W +RL N     A   P   L +     +VGI+LDYE G LSFYN    +HIYTF+
Sbjct: 395 ETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFT 454

Query: 311 NTFMEKLYPYFCPCLNDGGENKEPLHILHP 340
           +TF EKL+P F P +  G +N  PL I  P
Sbjct: 455 DTFTEKLWPLFYPGIRAGRKNAAPLTIRPP 484


>gi|217035095 tripartite motif-containing 62 [Homo sapiens]
          Length = 475

 Score =  187 bits (474), Expect = 2e-47
 Identities = 111/339 (32%), Positives = 179/339 (52%), Gaps = 5/339 (1%)

Query: 1   MEEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEK 60
           ++ EL  Q   L+ + +E      + K  +A  K +   L+  +   F +LH+ L  ++K
Sbjct: 135 LQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAFERLHRLLRERQK 194

Query: 61  DILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHS 120
            +L EL  +      ++E  + +  +Q    ++    +Q +  + +   FL  + +L   
Sbjct: 195 AMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHTFLAGVASLSER 254

Query: 121 LEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLS 180
           L+   K+  T  L        +Y GP+QY +W+ +   + P  + LTLDP TAH  L+LS
Sbjct: 255 LKG--KIHETN-LTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDPGTAHQRLILS 311

Query: 181 KSQTSVWHGDIK-KIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRES 239
              T V +G++  + + D P+RFD  V+VLGS  F+SG  YWEV VA+KT+W +G+  E+
Sbjct: 312 DDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLAHEA 371

Query: 240 IIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYN 299
             RKGS  + P +GF+ + + +     A   P   L + + LDKVG++LDY+ G L FYN
Sbjct: 372 ASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLDYDQGLLIFYN 431

Query: 300 AKTMTHIYTFSNTFMEKLYPYFCPCLND-GGENKEPLHI 337
           A  M+ +YTF   F  KL  YF P  +   G+N +PL I
Sbjct: 432 ADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRI 470


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  184 bits (468), Expect = 8e-47
 Identities = 121/358 (33%), Positives = 184/358 (51%), Gaps = 33/358 (9%)

Query: 12  LETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREEGK 71
           LE  L+E+   ++ +++     K      +Q +  EF +LH+ L  +++ +L+ L EE +
Sbjct: 161 LEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQ 220

Query: 72  ALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLL------------- 118
            + + +  N + L ++      +   ++ K   Q+ F+ LKD+ + L             
Sbjct: 221 DILQRLRENAAHLGDKRRDLAHLAAEVEGKC-LQSGFEMLKDVKSTLEKNIPRKFGGSLS 279

Query: 119 ------HSLEQGM-------KVLATRELISRKLNLGQYKG--PIQYMVWREMQDTLCPGL 163
                 H    G+       + + T E+ S  + L +     P QY   R++   L   +
Sbjct: 280 TICPRDHKALLGLVKEINRCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQL---I 336

Query: 164 SPLTLDPKTAHPNLVLSKSQTSVWHGDIK-KIMPDDPERFDSSVAVLGSRGFTSGKWYWE 222
           + +TLDP+TAHPNLVLS+ + SV   + + + +PD P RF     VL + GFTSG+ YWE
Sbjct: 337 ADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWE 396

Query: 223 VEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLD 282
           VEV  KT W VGV R+S+ RKG     PE G+W +RL N     A   P   L +     
Sbjct: 397 VEVGDKTHWAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAATTTPFTPLHIKVKPK 456

Query: 283 KVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHP 340
           +VGI+LDYE G LSFYN    +HIYTF++TF EKL+P F P +  G +N  PL I  P
Sbjct: 457 RVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWPLFYPGIRAGRKNAAPLTIRPP 514


>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
          Length = 468

 Score =  177 bits (450), Expect = 9e-45
 Identities = 114/328 (34%), Positives = 178/328 (54%), Gaps = 14/328 (4%)

Query: 12  LETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREEGK 71
           L    KE Q +   +KE +   +E     +Q V  E++K+HQFL  +E+  L  L +E K
Sbjct: 146 LRVRRKEAQAVLTHEKERVKLCQEETKTCKQVVVSEYMKMHQFLKEEEQLQLQLLEQEEK 205

Query: 72  ALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATR 131
               ++  N  +L +Q      M+  I++ + Q ++F+ L+++   L   E    +L   
Sbjct: 206 ENMRKLRNNEIKLTQQIRSLSKMIAQIESSS-QSSAFESLEEVRGALERSEP--LLLQCP 262

Query: 132 ELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDI 191
           E  + +L+L +  G         M++ L    + +TLDP TA+  LVLS+   SV +G  
Sbjct: 263 EATTTELSLCRITG---------MKEMLRKFSTEITLDPATANAYLVLSEDLKSVKYGGS 313

Query: 192 KKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPE 251
           ++ +PD+PERFD S  VLG++ FTSG+ YWEVEV  KT+W VG+ ++S+ RKG+ P  P 
Sbjct: 314 RQQLPDNPERFDQSATVLGTQIFTSGRHYWEVEVGNKTEWEVGICKDSVSRKGNLPKPPG 373

Query: 252 QGFWLLRLRNQTDLKA-LDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFS 310
             F L+ L+   D    +  P     +   + KVG++LDYE G ++FYN    + IY+F 
Sbjct: 374 DLFSLIGLKIGDDYSLWVSSPLKGQHVREPVCKVGVFLDYESGHIAFYNGTDESLIYSFP 433

Query: 311 N-TFMEKLYPYFCPCLNDGGENKEPLHI 337
             +F E L P F PCL + G N +PL I
Sbjct: 434 QASFQEALRPIFSPCLPNEGTNTDPLTI 461


>gi|63054855 erythroblast membrane-associated protein precursor
           [Homo sapiens]
          Length = 475

 Score =  171 bits (434), Expect = 7e-43
 Identities = 98/245 (40%), Positives = 139/245 (56%), Gaps = 10/245 (4%)

Query: 95  LVSIQAKTEQQNSFDFLKDITTLL--HSLEQGMKVLATRELISRKLNLGQYKGPIQYMVW 152
           L+  Q + +++  ++ + ++  LL  H+ E+G    A ++L S      + K       W
Sbjct: 175 LIWKQRRAKEKLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSEL----KLKRAAANSGW 230

Query: 153 REMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSR 212
           R  +         +TLDP TAHP L+LS+ Q  V  GD ++ +PD+P+RFD  V++LGS 
Sbjct: 231 RRARLHFVA----VTLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSE 286

Query: 213 GFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPS 272
            FT+G  YWEV V  KTKW +GV  ES+ RKG    +P  G WLLR     + +AL  P 
Sbjct: 287 YFTTGCHYWEVYVGDKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQ 346

Query: 273 FSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLNDGGENK 332
            S  L      VGI+LDYE G +SFYN    +HI+TF++ F   L P+F PCL+DGG+N 
Sbjct: 347 TSFRLKEPPRCVGIFLDYEAGVISFYNVTNKSHIFTFTHNFSGPLRPFFEPCLHDGGKNT 406

Query: 333 EPLHI 337
            PL I
Sbjct: 407 APLVI 411


>gi|19923536 erythroblast membrane-associated protein precursor
           [Homo sapiens]
          Length = 475

 Score =  171 bits (434), Expect = 7e-43
 Identities = 98/245 (40%), Positives = 139/245 (56%), Gaps = 10/245 (4%)

Query: 95  LVSIQAKTEQQNSFDFLKDITTLL--HSLEQGMKVLATRELISRKLNLGQYKGPIQYMVW 152
           L+  Q + +++  ++ + ++  LL  H+ E+G    A ++L S      + K       W
Sbjct: 175 LIWKQRRAKEKLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSEL----KLKRAAANSGW 230

Query: 153 REMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSR 212
           R  +         +TLDP TAHP L+LS+ Q  V  GD ++ +PD+P+RFD  V++LGS 
Sbjct: 231 RRARLHFVA----VTLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSE 286

Query: 213 GFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPS 272
            FT+G  YWEV V  KTKW +GV  ES+ RKG    +P  G WLLR     + +AL  P 
Sbjct: 287 YFTTGCHYWEVYVGDKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQ 346

Query: 273 FSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLNDGGENK 332
            S  L      VGI+LDYE G +SFYN    +HI+TF++ F   L P+F PCL+DGG+N 
Sbjct: 347 TSFRLKEPPRCVGIFLDYEAGVISFYNVTNKSHIFTFTHNFSGPLRPFFEPCLHDGGKNT 406

Query: 333 EPLHI 337
            PL I
Sbjct: 407 APLVI 411


>gi|4557743 Mediterranean fever protein [Homo sapiens]
          Length = 781

 Score =  168 bits (426), Expect = 6e-42
 Identities = 109/361 (30%), Positives = 186/361 (51%), Gaps = 27/361 (7%)

Query: 3   EELAIQ-QGQLETTLKELQTLRNMQKEAIAAHKENKLH-------LQQHVSMEFLKLHQF 54
           EE+A++ + +++  L+ L+ LR   +E  +  +E  +        L+Q V  +  +++ F
Sbjct: 413 EEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYF 472

Query: 55  LHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDI 114
           L  +E   +  L + G+ + +  +   +++ +   L   ++  ++AK E Q+ ++ L+DI
Sbjct: 473 LEQQEHFFVASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAK-ECQSEWELLQDI 531

Query: 115 TTLLHSLEQGM--KVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLT----- 167
             +LH  +     +   T + I +K+ L   K        +   +TL   +         
Sbjct: 532 GDILHRAKTVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELI 591

Query: 168 ----------LDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSG 217
                     LD +TA+PNL+ S    SV  G+  + +PD P+RFDS + VLGS  F SG
Sbjct: 592 GAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSG 651

Query: 218 KWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTL 277
           + YWEVEV  KT W +G  + SI RKG+  L+PE G+W++ +  + + +A  +P   L +
Sbjct: 652 RRYWEVEVGDKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLI 711

Query: 278 TNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSN-TFMEKLYPYFCPCLNDGGENKEPLH 336
                +VGI++DY  G +SFYN    +HIYTF++ +F   L P F P   DGG+N  PL 
Sbjct: 712 KEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLT 771

Query: 337 I 337
           I
Sbjct: 772 I 772


>gi|30023818 tripartite motif protein 50A [Homo sapiens]
          Length = 487

 Score =  156 bits (395), Expect = 2e-38
 Identities = 107/354 (30%), Positives = 165/354 (46%), Gaps = 26/354 (7%)

Query: 1   MEEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQH-------VSMEFLKLHQ 53
           M+EELA    +L+   K++        E IA    N+  +          +  EF +LH 
Sbjct: 132 MKEELAALISELKQEQKKVD-------ELIAKLVNNRTRIVNESDVFSWVIRREFQELHH 184

Query: 54  FLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKD 113
            +  ++   L  +    + L   +++ L Q Q      ++ L   +   EQ  + D  K 
Sbjct: 185 LVDEEKARCLEGIGGHTRGLVASLDMQLEQAQG----TRERLAQAECVLEQFGNEDHHKF 240

Query: 114 ITTLLHSLEQGMKVLATRELISR----KLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLD 169
           I    HS+    ++   R L           G ++  I+  VW+ +   + P   PL LD
Sbjct: 241 IRKF-HSMASRAEMPQARPLEGAFSPISFKPGLHQADIKLTVWKRLFRKVLPAPEPLKLD 299

Query: 170 PKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKT 229
           P TAHP L LSK  T V  G + +     PERFD S  VL SRGF+ G+ YWEV V  K+
Sbjct: 300 PATAHPLLELSKGNTVVQCGLLAQRRASQPERFDYSTCVLASRGFSCGRHYWEVVVGSKS 359

Query: 230 KWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLD 289
            W +GV++ +  RKG    +PE G WL+ L+     +A   P   L +  +  ++G+YL 
Sbjct: 360 DWRLGVIKGTASRKGKLNRSPEHGVWLIGLKEGRVYEAFACPRVPLPVAGHPHRIGLYLH 419

Query: 290 YEGGQLSFYNA---KTMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHP 340
           YE G+L+F++A     +  +YTF   F  KLYP    C ++ G N  P+ +  P
Sbjct: 420 YEQGELTFFDADRPDDLRPLYTFQADFQGKLYPILDTCWHERGSNSLPMVLPPP 473


>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score =  154 bits (388), Expect = 1e-37
 Identities = 104/320 (32%), Positives = 159/320 (49%), Gaps = 9/320 (2%)

Query: 12  LETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREEGK 71
           L+  L++ +  R+ +K+      +     Q+ V  EF  L  FL  +E  +L  L E  +
Sbjct: 184 LKKELEDCEVFRSTEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSR 243

Query: 72  ALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQ--GMKVLA 129
            + ++   NL+QL  +      +   IQ +T Q+   DFL++  + L       G K   
Sbjct: 244 EVAQKQNENLAQLGVEITQLSKLSSQIQ-ETAQKPDLDFLQEFKSTLSRCSNVPGPKPTT 302

Query: 130 TRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSP-----LTLDPKTAHPNLVLSKSQT 184
               +  K+     K  +   + ++ ++ L   L       LTLDP TA+P L+LS    
Sbjct: 303 VSSEMKNKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLK 362

Query: 185 SVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKG 244
            V  G+  + +P+ P RFD++  VL S GF+SG+ +WEVEV  K  W  GV RES+ RKG
Sbjct: 363 GVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKG 422

Query: 245 SCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMT 304
             P TPE+G W L+L N     A+  P  S     +L +V + LD E G +SFY  + M 
Sbjct: 423 LTPFTPEEGVWALQL-NGGQYWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMR 481

Query: 305 HIYTFSNTFMEKLYPYFCPC 324
           H+YTF   F E+++P F  C
Sbjct: 482 HLYTFRVNFQERVFPLFSVC 501


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  153 bits (386), Expect = 2e-37
 Identities = 107/362 (29%), Positives = 186/362 (51%), Gaps = 29/362 (8%)

Query: 1   MEEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHL-------QQHVSMEFLKLHQ 53
           +EE +   + Q++  L  L+ +++++K   A  ++ +  L       ++ +  EF +L+ 
Sbjct: 132 LEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSLTQMEREKIVWEFEQLYH 191

Query: 54  FLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKD 113
            L   E  +L  L E   A+   +   ++Q          ++  ++ K +QQ + + L+D
Sbjct: 192 SLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLEEK-QQQPTRELLQD 250

Query: 114 ITTLLH---------------SLEQGMKVLATRELISRKLNLGQYKGPIQYMVWR--EMQ 156
           I   L                 L++ + + A + L   + +L Q+   +Q  + +  E++
Sbjct: 251 IGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTE-SLKQFTEKMQSDMEKIQELR 309

Query: 157 DTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTS 216
           +     +  +TLDP TA+P+L+LS +   V +  +++ +PD+PERF+    VLGS  F +
Sbjct: 310 EAQLYSVD-VTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIA 368

Query: 217 GKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLT 276
           G+ YWEVEV  K KWT+GV  +S+ RKG     P+ GFW + L    +  AL  P  +L 
Sbjct: 369 GRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYGKEYWALTSPMTALP 428

Query: 277 LTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSN-TFMEKLYPYFCPCLNDGGENKEPL 335
           L   L +VGI+LDY+ G++SFYN     H +TFS+ TF   + PYF    + GG++  PL
Sbjct: 429 LRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSLSYS-GGKSAAPL 487

Query: 336 HI 337
            I
Sbjct: 488 II 489


>gi|44680130 tripartite motif-containing 7 isoform 2 [Homo sapiens]
          Length = 329

 Score =  150 bits (380), Expect = 1e-36
 Identities = 100/291 (34%), Positives = 147/291 (50%), Gaps = 9/291 (3%)

Query: 41  QQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQA 100
           Q+ V  EF  L  FL  +E  +L  L E  + + ++   NL+QL  +      +   IQ 
Sbjct: 31  QEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQIQ- 89

Query: 101 KTEQQNSFDFLKDITTLLHSLEQ--GMKVLATRELISRKLNLGQYKGPIQYMVWREMQDT 158
           +T Q+   DFL++  + L       G K       +  K+     K  +   + ++ ++ 
Sbjct: 90  ETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKFKED 149

Query: 159 LCPGLSP-----LTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRG 213
           L   L       LTLDP TA+P L+LS     V  G+  + +P+ P RFD++  VL S G
Sbjct: 150 LRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCG 209

Query: 214 FTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSF 273
           F+SG+ +WEVEV  K  W  GV RES+ RKG  P TPE+G W L+L N     A+  P  
Sbjct: 210 FSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQL-NGGQYWAVTSPER 268

Query: 274 SLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPC 324
           S     +L +V + LD E G +SFY  + M H+YTF   F E+++P F  C
Sbjct: 269 SPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVC 319


>gi|44680128 tripartite motif-containing 7 isoform 3 [Homo sapiens]
          Length = 303

 Score =  150 bits (380), Expect = 1e-36
 Identities = 100/291 (34%), Positives = 147/291 (50%), Gaps = 9/291 (3%)

Query: 41  QQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQA 100
           Q+ V  EF  L  FL  +E  +L  L E  + + ++   NL+QL  +      +   IQ 
Sbjct: 5   QEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQIQ- 63

Query: 101 KTEQQNSFDFLKDITTLLHSLEQ--GMKVLATRELISRKLNLGQYKGPIQYMVWREMQDT 158
           +T Q+   DFL++  + L       G K       +  K+     K  +   + ++ ++ 
Sbjct: 64  ETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKFKED 123

Query: 159 LCPGLSP-----LTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRG 213
           L   L       LTLDP TA+P L+LS     V  G+  + +P+ P RFD++  VL S G
Sbjct: 124 LRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCG 183

Query: 214 FTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSF 273
           F+SG+ +WEVEV  K  W  GV RES+ RKG  P TPE+G W L+L N     A+  P  
Sbjct: 184 FSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQL-NGGQYWAVTSPER 242

Query: 274 SLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPC 324
           S     +L +V + LD E G +SFY  + M H+YTF   F E+++P F  C
Sbjct: 243 SPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVC 293


>gi|44680126 tripartite motif-containing 7 isoform 3 [Homo sapiens]
          Length = 303

 Score =  150 bits (380), Expect = 1e-36
 Identities = 100/291 (34%), Positives = 147/291 (50%), Gaps = 9/291 (3%)

Query: 41  QQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQA 100
           Q+ V  EF  L  FL  +E  +L  L E  + + ++   NL+QL  +      +   IQ 
Sbjct: 5   QEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQIQ- 63

Query: 101 KTEQQNSFDFLKDITTLLHSLEQ--GMKVLATRELISRKLNLGQYKGPIQYMVWREMQDT 158
           +T Q+   DFL++  + L       G K       +  K+     K  +   + ++ ++ 
Sbjct: 64  ETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKFKED 123

Query: 159 LCPGLSP-----LTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRG 213
           L   L       LTLDP TA+P L+LS     V  G+  + +P+ P RFD++  VL S G
Sbjct: 124 LRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCG 183

Query: 214 FTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSF 273
           F+SG+ +WEVEV  K  W  GV RES+ RKG  P TPE+G W L+L N     A+  P  
Sbjct: 184 FSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQL-NGGQYWAVTSPER 242

Query: 274 SLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPC 324
           S     +L +V + LD E G +SFY  + M H+YTF   F E+++P F  C
Sbjct: 243 SPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVC 293


>gi|44680124 tripartite motif-containing 7 isoform 3 [Homo sapiens]
          Length = 303

 Score =  150 bits (380), Expect = 1e-36
 Identities = 100/291 (34%), Positives = 147/291 (50%), Gaps = 9/291 (3%)

Query: 41  QQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQA 100
           Q+ V  EF  L  FL  +E  +L  L E  + + ++   NL+QL  +      +   IQ 
Sbjct: 5   QEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQIQ- 63

Query: 101 KTEQQNSFDFLKDITTLLHSLEQ--GMKVLATRELISRKLNLGQYKGPIQYMVWREMQDT 158
           +T Q+   DFL++  + L       G K       +  K+     K  +   + ++ ++ 
Sbjct: 64  ETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLKGMLKKFKED 123

Query: 159 LCPGLSP-----LTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRG 213
           L   L       LTLDP TA+P L+LS     V  G+  + +P+ P RFD++  VL S G
Sbjct: 124 LRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCG 183

Query: 214 FTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSF 273
           F+SG+ +WEVEV  K  W  GV RES+ RKG  P TPE+G W L+L N     A+  P  
Sbjct: 184 FSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQL-NGGQYWAVTSPER 242

Query: 274 SLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPC 324
           S     +L +V + LD E G +SFY  + M H+YTF   F E+++P F  C
Sbjct: 243 SPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVC 293


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score =  142 bits (358), Expect = 4e-34
 Identities = 100/311 (32%), Positives = 164/311 (52%), Gaps = 27/311 (8%)

Query: 41  QQHVSMEFLKLHQFLHSKEKD----------ILTELREEGKALNEEMELNLSQLQEQCLL 90
           +Q +  EF K  + L  K+             L  L+ E     +++ELN S+L +Q  +
Sbjct: 181 KQSIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQV 240

Query: 91  AKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYM 150
              M+  ++ ++++   +  L+DI  +L+  +     L   E IS +L     K   + +
Sbjct: 241 LWRMIAELKERSQRPVRW-MLQDIQEVLNRSKSWS--LQQPEPISLEL-----KTDCRVL 292

Query: 151 VWREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLG 210
             RE+  T     + + LDP TA+  L++S+ +  V +GD  + +PD+PERF     VLG
Sbjct: 293 GLREILKTYA---ADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLPDNPERFYRYNIVLG 349

Query: 211 SRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKA--L 268
           S+  +SG+ YWEVEV  +++W +GV ++++ RK    L+P  GFW++RLR   + +A   
Sbjct: 350 SQCISSGRHYWEVEVGDRSEWGLGVCKQNVDRKEVVYLSPHYGFWVIRLRKGNEYRAGTD 409

Query: 269 DLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTM-THIYTFSN-TFMEKLYPYFCPCLN 326
           + P  SL +     +VGI++DYE   +SFYN     +HI+TF    F  +L PYF PC +
Sbjct: 410 EYPILSLPVPPR--RVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFPGRLLPYFSPCYS 467

Query: 327 DGGENKEPLHI 337
            G  N  PL I
Sbjct: 468 IGTNNTAPLAI 478


>gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]
          Length = 526

 Score =  142 bits (357), Expect = 6e-34
 Identities = 76/158 (48%), Positives = 97/158 (61%), Gaps = 2/158 (1%)

Query: 166 LTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEV 225
           +TLDP TAHP+L L +   SV   D ++ +P+  ERFDS   VLG   FTSG+ YWEVEV
Sbjct: 305 VTLDPDTAHPHLFLYEDSKSVRLEDSRQKLPEKTERFDSWPCVLGRETFTSGRHYWEVEV 364

Query: 226 AKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVG 285
             +T W +GV RE++++KG  P+TPE GFW + L       AL      L L     +VG
Sbjct: 365 GDRTDWAIGVCRENVMKKGFDPMTPENGFWAVELYG-NGYWALTPLRTPLPLAGPPRRVG 423

Query: 286 IYLDYEGGQLSFYNAKTMTHIYTFSN-TFMEKLYPYFC 322
           I+LDYE G +SFYN    + IYTFSN TF   L P+FC
Sbjct: 424 IFLDYESGDISFYNMNDGSDIYTFSNVTFSGPLRPFFC 461


>gi|31881693 butyrophilin, subfamily 2, member A2 isoform b [Homo
           sapiens]
          Length = 407

 Score =  142 bits (357), Expect = 6e-34
 Identities = 74/157 (47%), Positives = 95/157 (60%), Gaps = 2/157 (1%)

Query: 166 LTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEV 225
           + LDP TAHP L LS+ + SV  G  ++ +PD+PERFDS   VLG   F SGK YWEVEV
Sbjct: 213 VVLDPDTAHPELFLSEDRRSVRRGPYRQRVPDNPERFDSQPCVLGWESFASGKHYWEVEV 272

Query: 226 AKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVG 285
                WTVGV R S+ RKG   L P+ GFW L +      +AL  P   L L  +L +VG
Sbjct: 273 ENVMVWTVGVCRHSVERKGEVLLIPQNGFWTLEMFG-NQYRALSSPERILPLKESLCRVG 331

Query: 286 IYLDYEGGQLSFYNAKTMTHIYTF-SNTFMEKLYPYF 321
           ++LDYE G +SFYN +  +HIYT   + F   + P+F
Sbjct: 332 VFLDYEAGDVSFYNMRDRSHIYTCPRSAFTVPVRPFF 368


>gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo
           sapiens]
          Length = 523

 Score =  142 bits (357), Expect = 6e-34
 Identities = 74/157 (47%), Positives = 95/157 (60%), Gaps = 2/157 (1%)

Query: 166 LTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEV 225
           + LDP TAHP L LS+ + SV  G  ++ +PD+PERFDS   VLG   F SGK YWEVEV
Sbjct: 329 VVLDPDTAHPELFLSEDRRSVRRGPYRQRVPDNPERFDSQPCVLGWESFASGKHYWEVEV 388

Query: 226 AKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVG 285
                WTVGV R S+ RKG   L P+ GFW L +      +AL  P   L L  +L +VG
Sbjct: 389 ENVMVWTVGVCRHSVERKGEVLLIPQNGFWTLEMFG-NQYRALSSPERILPLKESLCRVG 447

Query: 286 IYLDYEGGQLSFYNAKTMTHIYTF-SNTFMEKLYPYF 321
           ++LDYE G +SFYN +  +HIYT   + F   + P+F
Sbjct: 448 VFLDYEAGDVSFYNMRDRSHIYTCPRSAFTVPVRPFF 484


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  141 bits (356), Expect = 7e-34
 Identities = 117/348 (33%), Positives = 179/348 (51%), Gaps = 28/348 (8%)

Query: 1   MEEELAIQQGQLETTLKELQTLRNMQKE-----AI--AAHKENKLHLQQHVSMEFLKLHQ 53
           +EE     Q +L+  L EL+  + + ++     AI  A  K+     +  +  EF++   
Sbjct: 128 LEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKN 187

Query: 54  FLHSKEKDILTEL----REEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFD 109
           FL  +E+  L EL    RE+ + L E+ E  L+Q Q Q L     L+S   +    ++ +
Sbjct: 188 FLVEEEQRQLQELEKDEREQLRILGEK-EAKLAQ-QSQAL---QELISELDRRCHSSALE 242

Query: 110 FLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLD 169
            L+++  +L   E     L   ++ S +L    +   ++ M+        C     +TLD
Sbjct: 243 LLQEVIIVLERSESWN--LKDLDITSPELRSVCHVPGLKKML------RTCA--VHITLD 292

Query: 170 PKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKT 229
           P TA+P L+LS+ +  V  GD ++ +P + ERFDS   VLG++ F SGK YWEV+V  K 
Sbjct: 293 PDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKE 352

Query: 230 KWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLD 289
            W +GV R+S+ RKG   L+ + GFW + L N+   +A   P   L L     +VGI+LD
Sbjct: 353 AWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLD 412

Query: 290 YEGGQLSFYNAKTM-THIYTFSN-TFMEKLYPYFCPCLNDGGENKEPL 335
           YE G +SFYN     + IY+FS   F   L P+F P  NDGG+N  PL
Sbjct: 413 YEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPL 460


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score =  140 bits (354), Expect = 1e-33
 Identities = 97/334 (29%), Positives = 166/334 (49%), Gaps = 16/334 (4%)

Query: 7   IQQGQLETTLKELQTLRN---MQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDIL 63
           I +G LE     ++ +     +Q       K+   + ++ ++ EF ++  FL ++++ IL
Sbjct: 143 ILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKREEINSEFEQIRLFLQNEQEMIL 202

Query: 64  TELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQ 123
            ++++E   +  ++  NL +L +     K +L  ++ K+ Q N      ++ T   S+  
Sbjct: 203 RQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGKSVQSNL-----ELLTQAKSMHH 257

Query: 124 GMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQ 183
             + L   EL S +L    +  P QY     +   + P    + LD  TAHP L++S+ +
Sbjct: 258 KYQNLKCPELFSFRLTKYGFSLPPQYS---GLDRIIKPFQVDVILDLNTAHPQLLVSEDR 314

Query: 184 TSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRK 243
            +V +   K+ +  DP RF    AVLGS+ F+SG+ YWEVEV  K KW +GV ++ ++R 
Sbjct: 315 KAVRYERKKRNICYDPRRFYVCPAVLGSQRFSSGRHYWEVEVGNKPKWILGVCQDCLLRN 374

Query: 244 GSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTM 303
                +   GFW +    ++   A    +  L       K+GI+LDYE G LSFYN    
Sbjct: 375 WQDQPSVLGGFWAIGRYMKSGYVASGPKTTQLLPVVKPSKIGIFLDYELGDLSFYNMNDR 434

Query: 304 THIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHI 337
           + +YTF++ F E ++PYF       G + EPL I
Sbjct: 435 SILYTFNDCFTEAVWPYFYT-----GTDSEPLKI 463


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  140 bits (352), Expect = 2e-33
 Identities = 105/330 (31%), Positives = 163/330 (49%), Gaps = 36/330 (10%)

Query: 9   QGQLETTLKELQTLRNMQKEAIAAHK----ENKLHLQ-QHVSMEFLKLHQFLHSKEKDIL 63
           Q  LE   KEL+    + +EA    K    + K+ +Q Q   +EF K   FL  +E+  L
Sbjct: 144 QMALELMRKELEDA--LTQEANVGKKTVIWKEKVEMQRQRFRLEFEKHRGFLAQEEQRQL 201

Query: 64  TELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQ 123
             L  E +A  + +  + S+L +Q    K++   +Q + ++             L  LE 
Sbjct: 202 RRLEAEERATLQRLRESKSRLVQQSKALKELADELQERCQRP-----------ALGLLEG 250

Query: 124 GMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLC-PGLSPLT--------LDPKTAH 174
              VL+  + ++R   L     P+      E++   C PG   L         LDP TAH
Sbjct: 251 VRGVLSRSKAVTR---LEAENIPM------ELKTACCIPGRRELLRKFQVDVKLDPATAH 301

Query: 175 PNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVG 234
           P+L+L+    SV  G+  + +P++PERFD+   +LG + F+SG+ YWEV V +  +W +G
Sbjct: 302 PSLLLTADLRSVQDGEPWRDVPNNPERFDTWPCILGLQSFSSGRHYWEVLVGEGAEWGLG 361

Query: 235 VVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQ 294
           V ++++ RKG    +PE G W L L    +   L  PS  L    +   +GI+LDYE G+
Sbjct: 362 VCQDTLPRKGETTPSPENGVWALWLLKGNEYMVLASPSVPLLQLESPRCIGIFLDYEAGE 421

Query: 295 LSFYNAKTMTHIYTFSNTFMEKLYPYFCPC 324
           +SFYN    ++IYTF+  F   L PYF  C
Sbjct: 422 ISFYNVTDGSYIYTFNQLFSGLLRPYFFIC 451


>gi|222418658 butyrophilin, subfamily 3, member A1 isoform c [Homo
           sapiens]
          Length = 461

 Score =  138 bits (347), Expect = 8e-33
 Identities = 70/155 (45%), Positives = 97/155 (62%), Gaps = 1/155 (0%)

Query: 168 LDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAK 227
           LDPKTA+P L++S+ Q SV      + +PD+PERF+    VLG   F SG+ YWEVEV  
Sbjct: 292 LDPKTANPILLVSEDQRSVQRAKEPQDLPDNPERFNWHYCVLGCESFISGRHYWEVEVGD 351

Query: 228 KTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIY 287
           + +W +GV  +++ RKG   +TPE GFW + L +    + L  P  +L L     KVG++
Sbjct: 352 RKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTEPRTNLKLPKPPKKVGVF 411

Query: 288 LDYEGGQLSFYNAKTMTHIYTFSN-TFMEKLYPYF 321
           LDYE G +SFYNA   +HI+TF + +F E LYP F
Sbjct: 412 LDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVF 446


>gi|37595558 butyrophilin, subfamily 3, member A1 isoform a [Homo
           sapiens]
          Length = 513

 Score =  138 bits (347), Expect = 8e-33
 Identities = 70/155 (45%), Positives = 97/155 (62%), Gaps = 1/155 (0%)

Query: 168 LDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAK 227
           LDPKTA+P L++S+ Q SV      + +PD+PERF+    VLG   F SG+ YWEVEV  
Sbjct: 344 LDPKTANPILLVSEDQRSVQRAKEPQDLPDNPERFNWHYCVLGCESFISGRHYWEVEVGD 403

Query: 228 KTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIY 287
           + +W +GV  +++ RKG   +TPE GFW + L +    + L  P  +L L     KVG++
Sbjct: 404 RKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTEPRTNLKLPKPPKKVGVF 463

Query: 288 LDYEGGQLSFYNAKTMTHIYTFSN-TFMEKLYPYF 321
           LDYE G +SFYNA   +HI+TF + +F E LYP F
Sbjct: 464 LDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVF 498


>gi|5921461 butyrophilin, subfamily 2, member A1 isoform 1 precursor
           [Homo sapiens]
          Length = 527

 Score =  138 bits (347), Expect = 8e-33
 Identities = 83/221 (37%), Positives = 125/221 (56%), Gaps = 18/221 (8%)

Query: 118 LHSLEQGMKVLA--------TRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPL--- 166
           ++ L++  K+L+        TRE+  ++L   + +   +  V  ++Q+ L    + L   
Sbjct: 269 INKLQKEKKILSGEKEFERETREIALKELEKERVQKEEELQVKEKLQEELRWRRTFLHAV 328

Query: 167 --TLDPKTAHPNLVLSKSQTSVWHGDIKKI---MPDDPERFDSSVAVLGSRGFTSGKWYW 221
              LDP TAHP+L LS+ + SV     + +   +PD+PERFDS   VLG   F SGK YW
Sbjct: 329 DVVLDPDTAHPDLFLSEDRRSVRRCPFRHLGESVPDNPERFDSQPCVLGRESFASGKHYW 388

Query: 222 EVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNL 281
           EVEV    +WTVGV R+S+ RKG   L P+ GFW L + ++   +A+  P   L L  +L
Sbjct: 389 EVEVENVIEWTVGVCRDSVERKGEVLLIPQNGFWTLEM-HKGQYRAVSSPDRILPLKESL 447

Query: 282 DKVGIYLDYEGGQLSFYNAKTMTHIYTF-SNTFMEKLYPYF 321
            +VG++LDYE G +SFYN +  +HIYT   + F   + P+F
Sbjct: 448 CRVGVFLDYEAGDVSFYNMRDRSHIYTCPRSAFSVPVRPFF 488


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score =  137 bits (346), Expect = 1e-32
 Identities = 95/326 (29%), Positives = 159/326 (48%), Gaps = 15/326 (4%)

Query: 12  LETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREEGK 71
           L+  L +LQ L + Q +     +E   + +Q +S EF  L+QFL  +++ +L+ L EE K
Sbjct: 151 LKKQLADLQKLISTQSKKPLELREMVENQRQELSSEFEHLNQFLDREQQAVLSRLAEEEK 210

Query: 72  ALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATR 131
              +++  N++         K  L  +  +  + +  + L  I     S  +     ++ 
Sbjct: 211 DNQQKLSANITAFSNYSATLKSQLSKV-VELSELSELELLSQIKIFYESENE-----SSP 264

Query: 132 ELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDI 191
            + S  L       P QY     +Q  +      + LDP+TAHPNL++S+ +  V     
Sbjct: 265 SIFSIHLKRDGCSFPPQYSA---LQRIIKKFKVEIILDPETAHPNLIVSEDKKRVRFTKR 321

Query: 192 KKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPE 251
           K+ +P  P+RF     VLG   F SG+ +WE+EV  K++W +G+ ++S+  K   P + +
Sbjct: 322 KQKVPGFPKRFTVKPVVLGFPYFHSGRHFWEIEVGDKSEWAIGICKDSLPTKARRPSSAQ 381

Query: 252 QGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSN 311
           Q  W + L++         P+  L L      +GI+LDYE G++SFYN    +HI TF++
Sbjct: 382 QECWRIELQDDGYHAPGAFPT-PLLLEVKARAIGIFLDYEMGEISFYNMAEKSHICTFTD 440

Query: 312 TFMEKLYPYFCPCLNDGGENKEPLHI 337
           TF   L PYF       G + +PL I
Sbjct: 441 TFTGPLRPYFYV-----GPDSQPLRI 461


>gi|5901908 butyrophilin, subfamily 3, member A3 isoform a [Homo
           sapiens]
          Length = 584

 Score =  136 bits (342), Expect = 3e-32
 Identities = 71/156 (45%), Positives = 99/156 (63%), Gaps = 2/156 (1%)

Query: 168 LDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAK 227
           LDP TA+  L++S+ Q SV   +  + +PD+PERF+    VLG   FTSG+ YWEVEV  
Sbjct: 344 LDPDTANAILLVSEDQRSVQRAEEPRDLPDNPERFEWRYCVLGCENFTSGRHYWEVEVGD 403

Query: 228 KTKWTVGVVRESIIR-KGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGI 286
           + +W +GV  +++ R KG   +TPE G+W + L +    +AL  P  +L L     KVGI
Sbjct: 404 RKEWHIGVCSKNVERKKGWVKMTPENGYWTMGLTDGNKYRALTEPRTNLKLPEPPRKVGI 463

Query: 287 YLDYEGGQLSFYNAKTMTHIYTFSN-TFMEKLYPYF 321
           +LDYE G++SFYNA   +HIYTF + +F E LYP F
Sbjct: 464 FLDYETGEISFYNATDGSHIYTFPHASFSEPLYPVF 499


>gi|37574628 butyrophilin, subfamily 3, member A3 isoform b [Homo
           sapiens]
          Length = 542

 Score =  136 bits (342), Expect = 3e-32
 Identities = 71/156 (45%), Positives = 99/156 (63%), Gaps = 2/156 (1%)

Query: 168 LDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAK 227
           LDP TA+  L++S+ Q SV   +  + +PD+PERF+    VLG   FTSG+ YWEVEV  
Sbjct: 302 LDPDTANAILLVSEDQRSVQRAEEPRDLPDNPERFEWRYCVLGCENFTSGRHYWEVEVGD 361

Query: 228 KTKWTVGVVRESIIR-KGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGI 286
           + +W +GV  +++ R KG   +TPE G+W + L +    +AL  P  +L L     KVGI
Sbjct: 362 RKEWHIGVCSKNVERKKGWVKMTPENGYWTMGLTDGNKYRALTEPRTNLKLPEPPRKVGI 421

Query: 287 YLDYEGGQLSFYNAKTMTHIYTFSN-TFMEKLYPYF 321
           +LDYE G++SFYNA   +HIYTF + +F E LYP F
Sbjct: 422 FLDYETGEISFYNATDGSHIYTFPHASFSEPLYPVF 457


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  135 bits (339), Expect = 7e-32
 Identities = 95/305 (31%), Positives = 150/305 (49%), Gaps = 25/305 (8%)

Query: 41  QQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQA 100
           +Q+V  EF +L + L  +E+ +L  L EE   +   +    + L +Q     +++  ++ 
Sbjct: 175 RQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEG 234

Query: 101 KTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLC 160
           +  Q  +   L+DI   L  + Q +K+     +      + +  G ++         TL 
Sbjct: 235 RC-QLPALGLLQDIKDALRRV-QDVKLQPPEVVPMELRTVCRVPGLVE---------TLR 283

Query: 161 PGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWY 220
                +TLDP TA+P L+LS+ + SV  GD+++ +PD PERFD    VLG   FTSG+ Y
Sbjct: 284 RFRGDVTLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHY 343

Query: 221 WEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRN---QTDLKALDLPSFSLTL 277
           WEVEV  +T W +GV RE++ RK    L+   GFW+L        +  +AL        L
Sbjct: 344 WEVEVGDRTSWALGVCRENVNRKEKGELSAGNGFWILVFLGSYYNSSERAL------APL 397

Query: 278 TNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSN-TFMEKLYPYFCPCLNDGGENKEPLH 336
            +   +VGI+LDYE G LSFY+A   + ++ F    F   L P F P       +  P+ 
Sbjct: 398 RDPPRRVGIFLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLFSPL----SSSPTPMT 453

Query: 337 ILHPQ 341
           I  P+
Sbjct: 454 ICRPK 458


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,751,303
Number of Sequences: 37866
Number of extensions: 554267
Number of successful extensions: 2603
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 139
Number of HSP's successfully gapped in prelim test: 175
Number of HSP's that attempted gapping in prelim test: 2135
Number of HSP's gapped (non-prelim): 494
length of query: 341
length of database: 18,247,518
effective HSP length: 103
effective length of query: 238
effective length of database: 14,347,320
effective search space: 3414662160
effective search space used: 3414662160
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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