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Search of human proteins with 37577162
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|37577162 syntaxin 2 isoform 2 [Homo sapiens]
(288 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|37577162 syntaxin 2 isoform 2 [Homo sapiens] 558 e-159
gi|37577287 syntaxin 2 isoform 1 [Homo sapiens] 525 e-149
gi|16418379 syntaxin 1B [Homo sapiens] 368 e-102
gi|4759182 syntaxin 1A (brain) [Homo sapiens] 362 e-100
gi|4759184 syntaxin 3 [Homo sapiens] 350 1e-96
gi|20149560 syntaxin 4 [Homo sapiens] 233 1e-61
gi|33667038 syntaxin 11 [Homo sapiens] 169 3e-42
gi|49258196 syntaxin 19 [Homo sapiens] 140 1e-33
gi|170932494 syntaxin 7 [Homo sapiens] 102 3e-22
gi|28933465 syntaxin 12 [Homo sapiens] 94 1e-19
gi|47778943 syntaxin 16 isoform a [Homo sapiens] 69 4e-12
gi|198041692 syntaxin 16 isoform d [Homo sapiens] 69 4e-12
gi|198041688 syntaxin 16 isoform c [Homo sapiens] 69 4e-12
gi|34447229 syntaxin 16 isoform b [Homo sapiens] 69 4e-12
gi|223972648 t-SNARE domain containing 1 [Homo sapiens] 61 1e-09
gi|94400932 syntaxin 5 [Homo sapiens] 53 4e-07
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 49 4e-06
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 49 4e-06
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 49 4e-06
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 49 4e-06
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 49 5e-06
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 49 5e-06
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 47 2e-05
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 44 2e-04
gi|237858621 polyamine modulated factor 1 binding protein 1 isof... 43 3e-04
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 43 3e-04
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 43 3e-04
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 43 3e-04
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 43 3e-04
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 41 0.001
>gi|37577162 syntaxin 2 isoform 2 [Homo sapiens]
Length = 288
Score = 558 bits (1437), Expect = e-159
Identities = 288/288 (100%), Positives = 288/288 (100%)
Query: 1 MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSII 60
MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSII
Sbjct: 1 MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSII 60
Query: 61 LSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHS 120
LSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHS
Sbjct: 61 LSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHS 120
Query: 121 VLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDI 180
VLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDI
Sbjct: 121 VLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDI 180
Query: 181 ISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNAT 240
ISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNAT
Sbjct: 181 ISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNAT 240
Query: 241 DYVEHAKEETKKAIKYQSKARRKKWIIIAVSVVLVAIIALIIGLSVGK 288
DYVEHAKEETKKAIKYQSKARRKKWIIIAVSVVLVAIIALIIGLSVGK
Sbjct: 241 DYVEHAKEETKKAIKYQSKARRKKWIIIAVSVVLVAIIALIIGLSVGK 288
>gi|37577287 syntaxin 2 isoform 1 [Homo sapiens]
Length = 287
Score = 525 bits (1352), Expect = e-149
Identities = 269/286 (94%), Positives = 276/286 (96%)
Query: 1 MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSII 60
MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSII
Sbjct: 1 MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSII 60
Query: 61 LSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHS 120
LSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHS
Sbjct: 61 LSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHS 120
Query: 121 VLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDI 180
VLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDI
Sbjct: 121 VLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDI 180
Query: 181 ISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNAT 240
ISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNAT
Sbjct: 181 ISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNAT 240
Query: 241 DYVEHAKEETKKAIKYQSKARRKKWIIIAVSVVLVAIIALIIGLSV 286
DYVEHAKEETKKAIKYQSKARRK II +VL+ I+ +I+ ++
Sbjct: 241 DYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTL 286
>gi|16418379 syntaxin 1B [Homo sapiens]
Length = 288
Score = 368 bits (945), Expect = e-102
Identities = 186/287 (64%), Positives = 235/287 (81%)
Query: 1 MRDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSII 60
M+DR +L + + +DD + VV V++DHFMD+FF QVEEIR I+K+++ VE+VKK HS I
Sbjct: 1 MKDRTQELRSAKDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQHSAI 60
Query: 61 LSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHS 120
L+APNP+ K K+ELEDL +IKKTANK+R+KLKAIEQS +Q+E NR+S DLRIR+TQHS
Sbjct: 61 LAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKTQHS 120
Query: 121 VLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDI 180
LSRKFVE M EYN Q+ +R+R K RIQRQLEITGRTTT++ELE+MLESGK +IFT DI
Sbjct: 121 TLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFTDDI 180
Query: 181 ISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNAT 240
DSQ+T+QALNEIE+RH +I+KLETSIRELH+MF+DMAM VE+QGEMI+ IE NV ++
Sbjct: 181 KMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSV 240
Query: 241 DYVEHAKEETKKAIKYQSKARRKKWIIIAVSVVLVAIIALIIGLSVG 287
DYVE A +TKKA+KYQSKARRKK +II VVL ++A IG ++G
Sbjct: 241 DYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTLG 287
>gi|4759182 syntaxin 1A (brain) [Homo sapiens]
Length = 288
Score = 362 bits (929), Expect = e-100
Identities = 186/284 (65%), Positives = 228/284 (80%), Gaps = 1/284 (0%)
Query: 1 MRDRLPDL-TACRKNDDGDTVVVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSI 59
M+DR +L TA +DD D V V++D FMD+FF QVEEIR IDKI + VEEVK+ HS
Sbjct: 1 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSA 60
Query: 60 ILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQH 119
IL++PNP+ K KEELE+L +IKKTANK+R+KLK+IEQS +Q+E NR+S DLRIR+TQH
Sbjct: 61 ILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQH 120
Query: 120 SVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSD 179
S LSRKFVE M+EYN Q+ +RER KGRIQRQLEITGRTTT +ELE+MLESG P+IF S
Sbjct: 121 STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASG 180
Query: 180 IISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNA 239
II DS I++QAL+EIE+RH +I+KLE SIRELH+MFMDMAM VE+QGEMI+ IE NV +A
Sbjct: 181 IIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHA 240
Query: 240 TDYVEHAKEETKKAIKYQSKARRKKWIIIAVSVVLVAIIALIIG 283
DYVE A +TKKA+KYQSKARRKK +II V+L +IA +G
Sbjct: 241 VDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVG 284
>gi|4759184 syntaxin 3 [Homo sapiens]
Length = 289
Score = 350 bits (897), Expect = 1e-96
Identities = 186/290 (64%), Positives = 234/290 (80%), Gaps = 6/290 (2%)
Query: 1 MRDRLPDLTACRKNDDGDTVVV---VEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNH 57
M+DRL L A + D DT V ++ FMD+FF ++EE R +IDKI+++VEE KK +
Sbjct: 1 MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLY 60
Query: 58 SIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRT 117
SIILSAP PE K K++LE L EIKK AN +R KLK++E+ ++DE R+S DLRIR++
Sbjct: 61 SIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEV--RSSADLRIRKS 118
Query: 118 QHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFT 177
QHSVLSRKFVE M +YNEAQ FRERSKGRIQRQLEITG+ TTD+ELEEMLESG P+IFT
Sbjct: 119 QHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFT 178
Query: 178 SDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVM 237
S II DSQI++QAL+EIE RHKDI++LE+SI+ELH+MFMD+AM VE QGEM++NIE NVM
Sbjct: 179 SGII-DSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVM 237
Query: 238 NATDYVEHAKEETKKAIKYQSKARRKKWIIIAVSVVLVAIIALIIGLSVG 287
+ D+VE A++ETKKA+KYQS+AR+K III + VVL+ I+ALIIGLSVG
Sbjct: 238 HTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIGLSVG 287
>gi|20149560 syntaxin 4 [Homo sapiens]
Length = 297
Score = 233 bits (594), Expect = 1e-61
Identities = 123/259 (47%), Positives = 186/259 (71%), Gaps = 4/259 (1%)
Query: 30 DDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIR 89
++FFH+V IR +I K+ V+E++K IL+ P PE +K+EL++L EIK+ +IR
Sbjct: 39 EEFFHKVRTIRQTIVKLGNKVQELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIR 98
Query: 90 AKLKAIE-QSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRI 148
+LKAIE Q + DE+ N SV+ R+R+TQH VLS++FVE + + N Q+ +RE++ RI
Sbjct: 99 LQLKAIEPQKEEADENYN--SVNTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERI 156
Query: 149 QRQLEITGR-TTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETS 207
+RQL+IT +D+ELE+ML+SG+ +F S+I+ D+Q+TRQALNEI +RH +I +LE S
Sbjct: 157 RRQLKITNAGMVSDEELEQMLDSGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERS 216
Query: 208 IRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWII 267
IRELH++F +A VE QGEMIN IE+N++++ DYVE +E K A++ Q KAR+KK +I
Sbjct: 217 IRELHDIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKKKVLI 276
Query: 268 IAVSVVLVAIIALIIGLSV 286
+ V ++A+IIG++V
Sbjct: 277 AICVSITVVLLAVIIGVTV 295
>gi|33667038 syntaxin 11 [Homo sapiens]
Length = 287
Score = 169 bits (427), Expect = 3e-42
Identities = 93/272 (34%), Positives = 156/272 (57%), Gaps = 13/272 (4%)
Query: 1 MRDRLPDLTACRKN-----DDGDTV-------VVVEKDHFMDDFFHQVEEIRNSIDKITQ 48
M+DRL +L K DGD +V E DH ++ + + +I++ +
Sbjct: 1 MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA 60
Query: 49 YVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRT 108
V+ + K ++ L++ IK + + K IK I KL+A+++ + E+ +
Sbjct: 61 DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP 120
Query: 109 -SVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEM 167
S RI R Q++ L+ F AM +YN+A+ R+ K RIQRQLEI G+ + D++E+M
Sbjct: 121 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM 180
Query: 168 LESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGE 227
E GK +F+ ++++D + R ALNEIESRH+++++LE+ IR++HE+F+ MA+ VE Q +
Sbjct: 181 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD 240
Query: 228 MINNIERNVMNATDYVEHAKEETKKAIKYQSK 259
+N IE NV DY AK + +KA++Y+ K
Sbjct: 241 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEK 272
>gi|49258196 syntaxin 19 [Homo sapiens]
Length = 294
Score = 140 bits (353), Expect = 1e-33
Identities = 73/240 (30%), Positives = 139/240 (57%), Gaps = 2/240 (0%)
Query: 21 VVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKE 80
V+ E++ + H++++++ SI+ + V++ + ++++ +K E + KE
Sbjct: 39 VIYEREPVAERHLHEIQKLQESINNLADNVQKFGQQQKSLVASMRRFSLLKRE-STITKE 97
Query: 81 IKKTANKIRAKLKAIEQSFDQDESGNR-TSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTL 139
IK A I L + + + E N +SV RI ++QH+ + R F + M YN+
Sbjct: 98 IKIQAEYINRSLNDLVKEVKKSEVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAA 157
Query: 140 FRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHK 199
+E+ K I RQLE+ G+ +++++ +ML GK +F ++++ IT+ L+EIE RHK
Sbjct: 158 KQEKCKTFILRQLEVAGKEMSEEDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHK 217
Query: 200 DIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSK 259
+++ LE I++L ++F+ +++ VE QGE INNIE V + +YV + KE+ A+KY+ +
Sbjct: 218 ELVNLENQIKDLRDLFIQISLLVEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKR 277
>gi|170932494 syntaxin 7 [Homo sapiens]
Length = 261
Score = 102 bits (255), Expect = 3e-22
Identities = 70/249 (28%), Positives = 123/249 (49%), Gaps = 11/249 (4%)
Query: 37 EEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIE 96
+ I ++I KITQ E+++ + L P +++++L+ + + A K +
Sbjct: 16 QRISSNIQKITQCSVEIQRTLNQ-LGTPQDSPELRQQLQQKQQYTNQLA-------KETD 67
Query: 97 QSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSK---GRIQRQLE 153
+ + S T + R R+ Q L +F ++ + + Q ER K R++
Sbjct: 68 KYIKEFGSLPTTPSEQRQRKIQKDRLVAEFTTSLTNFQKVQRQAAEREKEFVARVRASSR 127
Query: 154 ITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHE 213
++G D E L S + + D +IT L I R I +LE I +++E
Sbjct: 128 VSGSFPEDSSKERNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINE 187
Query: 214 MFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWIIIAVSVV 273
+F D+ M + QG++I++IE NV NA +V+ A ++ +A YQ K+R+ III + V+
Sbjct: 188 IFKDLGMMIHEQGDVIDSIEANVENAEVHVQQANQQLSRAADYQRKSRKTLCIIILILVI 247
Query: 274 LVAIIALII 282
VAII+LII
Sbjct: 248 GVAIISLII 256
>gi|28933465 syntaxin 12 [Homo sapiens]
Length = 276
Score = 94.0 bits (232), Expect = 1e-19
Identities = 71/260 (27%), Positives = 124/260 (47%), Gaps = 15/260 (5%)
Query: 31 DFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLN---KEIKKTANK 87
DF ++ +I +I+Q ++K N L K++E L+ L ++ K N+
Sbjct: 21 DFSSIIQTCSGNIQRISQATAQIK-NLMSQLGTKQDSSKLQENLQQLQHSTNQLAKETNE 79
Query: 88 IRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGR 147
+ +L ++ E R +R Q L F A+ + Q E+ K
Sbjct: 80 LLKELGSLPLPLSTSEQ--------RQQRLQKERLMNDFSAALNNFQAVQRRVSEKEKES 131
Query: 148 IQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQ---ITRQALNEIESRHKDIMKL 204
I R + + + + EE L S + + S IT Q L I+ R I +L
Sbjct: 132 IARARAGSRLSAEERQREEQLVSFDSHEEWNQMQSQEDEVAITEQDLELIKERETAIRQL 191
Query: 205 ETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKK 264
E I +++++F D+AM + QG++I++IE NV ++ +VE A E+ ++A YQ K+R+K
Sbjct: 192 EADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATEQLQRAAYYQKKSRKKM 251
Query: 265 WIIIAVSVVLVAIIALIIGL 284
I++ V V++ I+ LII L
Sbjct: 252 CILVLVLSVIILILGLIIWL 271
>gi|47778943 syntaxin 16 isoform a [Homo sapiens]
Length = 325
Score = 69.3 bits (168), Expect = 4e-12
Identities = 54/253 (21%), Positives = 121/253 (47%), Gaps = 16/253 (6%)
Query: 36 VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEE--LEDLNKEIKKTANKIRAKLK 93
V+EI+ + +I Q ++E+ H L+ P + +EE +E +EI + ++ + ++
Sbjct: 82 VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 141
Query: 94 AIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLE 153
A+ + + + R+ + L++ E + AQ+ + +R K R +R
Sbjct: 142 AL-----PSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQH 196
Query: 154 ITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNE--IESRHKDIMKLETSIREL 211
D +++ G + ++ Q+ N +E R ++I ++ SI +L
Sbjct: 197 FF------DTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDL 250
Query: 212 HEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWIIIAVS 271
+E+F D+ + QG +++ I+ NV + E ++ KA +YQ K RK +I+ +
Sbjct: 251 NEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKK-NRKMLVILILF 309
Query: 272 VVLVAIIALIIGL 284
V+++ +I +++G+
Sbjct: 310 VIIIVLIVVLVGV 322
>gi|198041692 syntaxin 16 isoform d [Homo sapiens]
Length = 308
Score = 69.3 bits (168), Expect = 4e-12
Identities = 54/253 (21%), Positives = 121/253 (47%), Gaps = 16/253 (6%)
Query: 36 VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEE--LEDLNKEIKKTANKIRAKLK 93
V+EI+ + +I Q ++E+ H L+ P + +EE +E +EI + ++ + ++
Sbjct: 65 VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 124
Query: 94 AIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLE 153
A+ + + + R+ + L++ E + AQ+ + +R K R +R
Sbjct: 125 AL-----PSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQH 179
Query: 154 ITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNE--IESRHKDIMKLETSIREL 211
D +++ G + ++ Q+ N +E R ++I ++ SI +L
Sbjct: 180 FF------DTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDL 233
Query: 212 HEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWIIIAVS 271
+E+F D+ + QG +++ I+ NV + E ++ KA +YQ K RK +I+ +
Sbjct: 234 NEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKK-NRKMLVILILF 292
Query: 272 VVLVAIIALIIGL 284
V+++ +I +++G+
Sbjct: 293 VIIIVLIVVLVGV 305
>gi|198041688 syntaxin 16 isoform c [Homo sapiens]
Length = 321
Score = 69.3 bits (168), Expect = 4e-12
Identities = 54/253 (21%), Positives = 121/253 (47%), Gaps = 16/253 (6%)
Query: 36 VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEE--LEDLNKEIKKTANKIRAKLK 93
V+EI+ + +I Q ++E+ H L+ P + +EE +E +EI + ++ + ++
Sbjct: 78 VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 137
Query: 94 AIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLE 153
A+ + + + R+ + L++ E + AQ+ + +R K R +R
Sbjct: 138 AL-----PSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQH 192
Query: 154 ITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNE--IESRHKDIMKLETSIREL 211
D +++ G + ++ Q+ N +E R ++I ++ SI +L
Sbjct: 193 FF------DTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDL 246
Query: 212 HEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWIIIAVS 271
+E+F D+ + QG +++ I+ NV + E ++ KA +YQ K RK +I+ +
Sbjct: 247 NEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKK-NRKMLVILILF 305
Query: 272 VVLVAIIALIIGL 284
V+++ +I +++G+
Sbjct: 306 VIIIVLIVVLVGV 318
>gi|34447229 syntaxin 16 isoform b [Homo sapiens]
Length = 304
Score = 69.3 bits (168), Expect = 4e-12
Identities = 54/253 (21%), Positives = 121/253 (47%), Gaps = 16/253 (6%)
Query: 36 VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEE--LEDLNKEIKKTANKIRAKLK 93
V+EI+ + +I Q ++E+ H L+ P + +EE +E +EI + ++ + ++
Sbjct: 61 VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 120
Query: 94 AIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLE 153
A+ + + + R+ + L++ E + AQ+ + +R K R +R
Sbjct: 121 AL-----PSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQH 175
Query: 154 ITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNE--IESRHKDIMKLETSIREL 211
D +++ G + ++ Q+ N +E R ++I ++ SI +L
Sbjct: 176 FF------DTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDL 229
Query: 212 HEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWIIIAVS 271
+E+F D+ + QG +++ I+ NV + E ++ KA +YQ K RK +I+ +
Sbjct: 230 NEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKK-NRKMLVILILF 288
Query: 272 VVLVAIIALIIGL 284
V+++ +I +++G+
Sbjct: 289 VIIIVLIVVLVGV 301
>gi|223972648 t-SNARE domain containing 1 [Homo sapiens]
Length = 513
Score = 61.2 bits (147), Expect = 1e-09
Identities = 55/264 (20%), Positives = 124/264 (46%), Gaps = 24/264 (9%)
Query: 37 EEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEEL----EDLNKEIKKTANKIRAKL 92
+E+ ++ +I V ++++ L P+ ++++ L ++ NK I +A+ ++
Sbjct: 262 QEMSANVFRINSSVTSLERSLQS-LGTPSDTQELRDSLHTAQQETNKTIAASASSVKQMA 320
Query: 93 KAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQL 152
+ + S Q+ L+ R Q L + +A+ Y Q E+S+ +
Sbjct: 321 ELLRSSCPQER--------LQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLP-MA 371
Query: 153 EITGRTTTDDELEEMLESGKPSIFT-SDIISDSQ-------ITRQALNEIESRHKDIMKL 204
+ + + E+ + K +F SD + Q IT + L I R + I+++
Sbjct: 372 QRGSKQSPQAPFAELADDEK--VFNGSDNMWQGQEQALLPDITEEDLEAIRLREEAILQM 429
Query: 205 ETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKK 264
E+++ +++++ D+A V QGE +++IE ++ A+ + E A++ A ++Q + + K
Sbjct: 430 ESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHAEAARQLLAGASRHQLQRHKIK 489
Query: 265 WIIIAVSVVLVAIIALIIGLSVGK 288
++ V + +I +II SV K
Sbjct: 490 CCFLSAGVTALLVIIIIIATSVRK 513
>gi|94400932 syntaxin 5 [Homo sapiens]
Length = 355
Score = 52.8 bits (125), Expect = 4e-07
Identities = 51/223 (22%), Positives = 97/223 (43%), Gaps = 20/223 (8%)
Query: 70 IKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEA 129
IK+++ LNK+I + + +RA K + N V L+ + S + +E
Sbjct: 139 IKQDINSLNKQIAQLQDFVRA--KGSQSGRHLQTHSNTIVVSLQSKLASMSNDFKSVLEV 196
Query: 130 MAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDEL-EEMLESGKPSIFTSDIISDSQITR 188
E L ++RS+ + ++ + L + G S + D+ D +R
Sbjct: 197 RTE-----NLKQQRSRREQFSRAPVSALPLAPNHLGGGAVVLGAESHASKDVAIDMMDSR 251
Query: 189 -----QALNE----IESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNA 239
Q ++E I+SR + +E++I EL +F +A V+ Q E I I+ NV+ A
Sbjct: 252 TSQQLQLIDEQDSYIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEETIQRIDENVLGA 311
Query: 240 TDYVEHAKEETKKAIKYQSKARRKKWIIIAVSVVLVAIIALII 282
VE A E +KY +W+++ + ++L+ + +
Sbjct: 312 QLDVEAAHSE---ILKYFQSVTSNRWLMVKIFLILIVFFIIFV 351
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 49.3 bits (116), Expect = 4e-06
Identities = 45/227 (19%), Positives = 99/227 (43%), Gaps = 16/227 (7%)
Query: 37 EEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKE------IKKTANKIRA 90
EE++ ++ ++ +E+ + ++ + EG I + EDL+ E +K +
Sbjct: 1090 EELQAALARLD---DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1146
Query: 91 KLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQR 150
+L+A++ + T +LR +R Q + +K ++ +EAQ +E + Q
Sbjct: 1147 ELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQV--QEMRQKHAQA 1204
Query: 151 QLEITGRTTTDDELEEMLESGKPSI--FTSDIISDSQITRQALNEIESRHKDIMKLETSI 208
E+T + + L+ K ++ +D+ + ++ QA E+E + K KLE +
Sbjct: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK---KLEAQV 1261
Query: 209 RELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIK 255
+EL D + ++ ++ V + T + A+ + K K
Sbjct: 1262 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1308
Score = 36.2 bits (82), Expect = 0.034
Identities = 50/279 (17%), Positives = 121/279 (43%), Gaps = 56/279 (20%)
Query: 29 MDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKI 88
+++ Q+E+ + + + + + ++K ++ + G+ K+E+E K+++ ++
Sbjct: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1264
Query: 89 RAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSV----------------LSRKFVEAMAE 132
++K E++ R ++ ++ + Q+ V L++ ++
Sbjct: 1265 QSKCSDGERA--------RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1316
Query: 133 YNEAQTLFRERSKGRIQ-----RQLEITGRTTTDDELEEMLESG---KPSIFTSDI-ISD 183
+ Q L +E ++ ++ RQLE R + D+L+E +E+ + I T +I +SD
Sbjct: 1317 LQDTQELLQEETRQKLNVSTKLRQLE-EERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1375
Query: 184 SQ-------ITRQALNEIESR-HKDIM--------------KLETSIRELHEMFMDMAMF 221
S+ T +AL E + R K+I KLE + L + D+ +
Sbjct: 1376 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1435
Query: 222 VETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKA 260
++ Q ++++N+E+ + K + K + +A
Sbjct: 1436 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA 1474
Score = 35.4 bits (80), Expect = 0.058
Identities = 51/263 (19%), Positives = 104/263 (39%), Gaps = 38/263 (14%)
Query: 29 MDDFFHQVEEIRNSIDKITQYVEEVKKN-----------HSIILSAPNPEGKIKEELEDL 77
M DF ++E+ R S D+I +E +K + +A + E E+L
Sbjct: 1654 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1713
Query: 78 NKEIKKTAN----------KIRAKLKAIEQSFDQDESGNRTSVDLRIRRT--QHSVLSRK 125
+E+ + + ++ A++ +E+ ++E GN ++ R+R+ Q LS +
Sbjct: 1714 AEELASSLSGRNALQDEKRRLEARIAQLEEEL-EEEQGNMEAMSDRVRKATQQAEQLSNE 1772
Query: 126 FV--EAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISD 183
+ A+ NE+ ER ++ +L E+E ++S S +
Sbjct: 1773 LATERSTAQKNESARQQLERQNKELRSKLH---------EMEGAVKSKFKSTIAALEAKI 1823
Query: 184 SQITRQALNEIESRHKDIMKLETSIRELHEMFM---DMAMFVETQGEMINNIERNVMNAT 240
+Q+ Q E + L+ ++L E+ + D E E V
Sbjct: 1824 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLK 1883
Query: 241 DYVEHAKEETKKAIKYQSKARRK 263
+E A+EE+++ + K +R+
Sbjct: 1884 RQLEEAEEESQRINANRRKLQRE 1906
Score = 33.5 bits (75), Expect = 0.22
Identities = 35/222 (15%), Positives = 85/222 (38%), Gaps = 26/222 (11%)
Query: 36 VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAI 95
+E + + + K TQ E++ + S +++LE NKE +R+KL +
Sbjct: 1752 MEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE-------LRSKLHEM 1804
Query: 96 EQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEIT 155
E + +++ +I + + V + E A +++ K + L++
Sbjct: 1805 EGAVKSKFKSTIAALEAKIAQLEEQV-----EQEAREKQAATKSLKQKDKKLKEILLQVE 1859
Query: 156 GRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMF 215
++ +E E G + +Q ++E ++ ++ + R+L
Sbjct: 1860 DERKMAEQYKEQAEKGNARV------------KQLKRQLEEAEEESQRINANRRKLQREL 1907
Query: 216 MDMAMFVETQGEMINNIERNVM--NATDYVEHAKEETKKAIK 255
+ E G +N ++ + N T +V + ++ I+
Sbjct: 1908 DEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIE 1949
Score = 31.2 bits (69), Expect = 1.1
Identities = 39/204 (19%), Positives = 88/204 (43%), Gaps = 14/204 (6%)
Query: 51 EEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSV 110
EE + + + + + EEL + ++ K+ +A L +Q+ +++ + +
Sbjct: 1185 EETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA----KANLDKNKQTLEKENAD--LAG 1238
Query: 111 DLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLES 170
+LR+ + K + A+ E Q+ + + R + ++ + + ML
Sbjct: 1239 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1298
Query: 171 --GKPSIFTSDIISDS---QITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQ 225
GK D+ S S Q T++ L E E+R K + + T +R+L E + ++ +
Sbjct: 1299 AEGKAIKLAKDVASLSSQLQDTQELLQE-ETRQK--LNVSTKLRQLEEERNSLQDQLDEE 1355
Query: 226 GEMINNIERNVMNATDYVEHAKEE 249
E N+ER++ + +K++
Sbjct: 1356 MEAKQNLERHISTLNIQLSDSKKK 1379
Score = 29.6 bits (65), Expect = 3.2
Identities = 38/250 (15%), Positives = 102/250 (40%), Gaps = 29/250 (11%)
Query: 25 KDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKT 84
K+ + V ++ N ++ ++ +K ++ N K +E + E ++
Sbjct: 1422 KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREK 1481
Query: 85 ANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERS 144
K + +A+E++ + E RT + +L + + ++ ++ E
Sbjct: 1482 ETKALSLARALEEALEAKEELERT----------NKMLKAEMEDLVSSKDDVGKNVHELE 1531
Query: 145 KGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQAL-----NEIESRHK 199
K + + ++ T +ELE+ L++ T D ++ QAL ++++R +
Sbjct: 1532 KSKRALETQMEEMKTQLEELEDELQA------TEDAKLRLEVNMQALKGQFERDLQARDE 1585
Query: 200 DIMKLETSI-RELHEMFMDM-------AMFVETQGEMINNIERNVMNATDYVEHAKEETK 251
+ + R+LHE ++ A+ + ++ +++ + A ++ +E K
Sbjct: 1586 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1645
Query: 252 KAIKYQSKAR 261
+ K Q++ +
Sbjct: 1646 QLRKLQAQMK 1655
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 49.3 bits (116), Expect = 4e-06
Identities = 45/227 (19%), Positives = 99/227 (43%), Gaps = 16/227 (7%)
Query: 37 EEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKE------IKKTANKIRA 90
EE++ ++ ++ +E+ + ++ + EG I + EDL+ E +K +
Sbjct: 1097 EELQAALARLD---DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1153
Query: 91 KLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQR 150
+L+A++ + T +LR +R Q + +K ++ +EAQ +E + Q
Sbjct: 1154 ELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQV--QEMRQKHAQA 1211
Query: 151 QLEITGRTTTDDELEEMLESGKPSI--FTSDIISDSQITRQALNEIESRHKDIMKLETSI 208
E+T + + L+ K ++ +D+ + ++ QA E+E + K KLE +
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK---KLEAQV 1268
Query: 209 RELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIK 255
+EL D + ++ ++ V + T + A+ + K K
Sbjct: 1269 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1315
Score = 36.2 bits (82), Expect = 0.034
Identities = 50/279 (17%), Positives = 121/279 (43%), Gaps = 56/279 (20%)
Query: 29 MDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKI 88
+++ Q+E+ + + + + + ++K ++ + G+ K+E+E K+++ ++
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1271
Query: 89 RAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSV----------------LSRKFVEAMAE 132
++K E++ R ++ ++ + Q+ V L++ ++
Sbjct: 1272 QSKCSDGERA--------RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1323
Query: 133 YNEAQTLFRERSKGRIQ-----RQLEITGRTTTDDELEEMLESG---KPSIFTSDI-ISD 183
+ Q L +E ++ ++ RQLE R + D+L+E +E+ + I T +I +SD
Sbjct: 1324 LQDTQELLQEETRQKLNVSTKLRQLE-EERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1382
Query: 184 SQ-------ITRQALNEIESR-HKDIM--------------KLETSIRELHEMFMDMAMF 221
S+ T +AL E + R K+I KLE + L + D+ +
Sbjct: 1383 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1442
Query: 222 VETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKA 260
++ Q ++++N+E+ + K + K + +A
Sbjct: 1443 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA 1481
Score = 35.4 bits (80), Expect = 0.058
Identities = 51/263 (19%), Positives = 104/263 (39%), Gaps = 38/263 (14%)
Query: 29 MDDFFHQVEEIRNSIDKITQYVEEVKKN-----------HSIILSAPNPEGKIKEELEDL 77
M DF ++E+ R S D+I +E +K + +A + E E+L
Sbjct: 1661 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1720
Query: 78 NKEIKKTAN----------KIRAKLKAIEQSFDQDESGNRTSVDLRIRRT--QHSVLSRK 125
+E+ + + ++ A++ +E+ ++E GN ++ R+R+ Q LS +
Sbjct: 1721 AEELASSLSGRNALQDEKRRLEARIAQLEEEL-EEEQGNMEAMSDRVRKATQQAEQLSNE 1779
Query: 126 FV--EAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISD 183
+ A+ NE+ ER ++ +L E+E ++S S +
Sbjct: 1780 LATERSTAQKNESARQQLERQNKELRSKLH---------EMEGAVKSKFKSTIAALEAKI 1830
Query: 184 SQITRQALNEIESRHKDIMKLETSIRELHEMFM---DMAMFVETQGEMINNIERNVMNAT 240
+Q+ Q E + L+ ++L E+ + D E E V
Sbjct: 1831 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLK 1890
Query: 241 DYVEHAKEETKKAIKYQSKARRK 263
+E A+EE+++ + K +R+
Sbjct: 1891 RQLEEAEEESQRINANRRKLQRE 1913
Score = 33.5 bits (75), Expect = 0.22
Identities = 35/222 (15%), Positives = 85/222 (38%), Gaps = 26/222 (11%)
Query: 36 VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAI 95
+E + + + K TQ E++ + S +++LE NKE +R+KL +
Sbjct: 1759 MEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE-------LRSKLHEM 1811
Query: 96 EQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEIT 155
E + +++ +I + + V + E A +++ K + L++
Sbjct: 1812 EGAVKSKFKSTIAALEAKIAQLEEQV-----EQEAREKQAATKSLKQKDKKLKEILLQVE 1866
Query: 156 GRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMF 215
++ +E E G + +Q ++E ++ ++ + R+L
Sbjct: 1867 DERKMAEQYKEQAEKGNARV------------KQLKRQLEEAEEESQRINANRRKLQREL 1914
Query: 216 MDMAMFVETQGEMINNIERNVM--NATDYVEHAKEETKKAIK 255
+ E G +N ++ + N T +V + ++ I+
Sbjct: 1915 DEATESNEAMGREVNALKSKLRRGNETSFVPSRRSGGRRVIE 1956
Score = 31.2 bits (69), Expect = 1.1
Identities = 39/204 (19%), Positives = 88/204 (43%), Gaps = 14/204 (6%)
Query: 51 EEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSV 110
EE + + + + + EEL + ++ K+ +A L +Q+ +++ + +
Sbjct: 1192 EETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA----KANLDKNKQTLEKENAD--LAG 1245
Query: 111 DLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLES 170
+LR+ + K + A+ E Q+ + + R + ++ + + ML
Sbjct: 1246 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1305
Query: 171 --GKPSIFTSDIISDS---QITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQ 225
GK D+ S S Q T++ L E E+R K + + T +R+L E + ++ +
Sbjct: 1306 AEGKAIKLAKDVASLSSQLQDTQELLQE-ETRQK--LNVSTKLRQLEEERNSLQDQLDEE 1362
Query: 226 GEMINNIERNVMNATDYVEHAKEE 249
E N+ER++ + +K++
Sbjct: 1363 MEAKQNLERHISTLNIQLSDSKKK 1386
Score = 29.6 bits (65), Expect = 3.2
Identities = 38/250 (15%), Positives = 102/250 (40%), Gaps = 29/250 (11%)
Query: 25 KDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKT 84
K+ + V ++ N ++ ++ +K ++ N K +E + E ++
Sbjct: 1429 KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREK 1488
Query: 85 ANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERS 144
K + +A+E++ + E RT + +L + + ++ ++ E
Sbjct: 1489 ETKALSLARALEEALEAKEELERT----------NKMLKAEMEDLVSSKDDVGKNVHELE 1538
Query: 145 KGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQAL-----NEIESRHK 199
K + + ++ T +ELE+ L++ T D ++ QAL ++++R +
Sbjct: 1539 KSKRALETQMEEMKTQLEELEDELQA------TEDAKLRLEVNMQALKGQFERDLQARDE 1592
Query: 200 DIMKLETSI-RELHEMFMDM-------AMFVETQGEMINNIERNVMNATDYVEHAKEETK 251
+ + R+LHE ++ A+ + ++ +++ + A ++ +E K
Sbjct: 1593 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1652
Query: 252 KAIKYQSKAR 261
+ K Q++ +
Sbjct: 1653 QLRKLQAQMK 1662
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 49.3 bits (116), Expect = 4e-06
Identities = 45/227 (19%), Positives = 99/227 (43%), Gaps = 16/227 (7%)
Query: 37 EEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKE------IKKTANKIRA 90
EE++ ++ ++ +E+ + ++ + EG I + EDL+ E +K +
Sbjct: 1097 EELQAALARLD---DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1153
Query: 91 KLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQR 150
+L+A++ + T +LR +R Q + +K ++ +EAQ +E + Q
Sbjct: 1154 ELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQV--QEMRQKHAQA 1211
Query: 151 QLEITGRTTTDDELEEMLESGKPSI--FTSDIISDSQITRQALNEIESRHKDIMKLETSI 208
E+T + + L+ K ++ +D+ + ++ QA E+E + K KLE +
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK---KLEAQV 1268
Query: 209 RELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIK 255
+EL D + ++ ++ V + T + A+ + K K
Sbjct: 1269 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1315
Score = 36.2 bits (82), Expect = 0.034
Identities = 50/279 (17%), Positives = 121/279 (43%), Gaps = 56/279 (20%)
Query: 29 MDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKI 88
+++ Q+E+ + + + + + ++K ++ + G+ K+E+E K+++ ++
Sbjct: 1212 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1271
Query: 89 RAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSV----------------LSRKFVEAMAE 132
++K E++ R ++ ++ + Q+ V L++ ++
Sbjct: 1272 QSKCSDGERA--------RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1323
Query: 133 YNEAQTLFRERSKGRIQ-----RQLEITGRTTTDDELEEMLESG---KPSIFTSDI-ISD 183
+ Q L +E ++ ++ RQLE R + D+L+E +E+ + I T +I +SD
Sbjct: 1324 LQDTQELLQEETRQKLNVSTKLRQLE-EERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1382
Query: 184 SQ-------ITRQALNEIESR-HKDIM--------------KLETSIRELHEMFMDMAMF 221
S+ T +AL E + R K+I KLE + L + D+ +
Sbjct: 1383 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1442
Query: 222 VETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKA 260
++ Q ++++N+E+ + K + K + +A
Sbjct: 1443 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA 1481
Score = 35.4 bits (80), Expect = 0.058
Identities = 51/263 (19%), Positives = 104/263 (39%), Gaps = 38/263 (14%)
Query: 29 MDDFFHQVEEIRNSIDKITQYVEEVKKN-----------HSIILSAPNPEGKIKEELEDL 77
M DF ++E+ R S D+I +E +K + +A + E E+L
Sbjct: 1661 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1720
Query: 78 NKEIKKTAN----------KIRAKLKAIEQSFDQDESGNRTSVDLRIRRT--QHSVLSRK 125
+E+ + + ++ A++ +E+ ++E GN ++ R+R+ Q LS +
Sbjct: 1721 AEELASSLSGRNALQDEKRRLEARIAQLEEEL-EEEQGNMEAMSDRVRKATQQAEQLSNE 1779
Query: 126 FV--EAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISD 183
+ A+ NE+ ER ++ +L E+E ++S S +
Sbjct: 1780 LATERSTAQKNESARQQLERQNKELRSKLH---------EMEGAVKSKFKSTIAALEAKI 1830
Query: 184 SQITRQALNEIESRHKDIMKLETSIRELHEMFM---DMAMFVETQGEMINNIERNVMNAT 240
+Q+ Q E + L+ ++L E+ + D E E V
Sbjct: 1831 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLK 1890
Query: 241 DYVEHAKEETKKAIKYQSKARRK 263
+E A+EE+++ + K +R+
Sbjct: 1891 RQLEEAEEESQRINANRRKLQRE 1913
Score = 31.2 bits (69), Expect = 1.1
Identities = 39/204 (19%), Positives = 88/204 (43%), Gaps = 14/204 (6%)
Query: 51 EEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSV 110
EE + + + + + EEL + ++ K+ +A L +Q+ +++ + +
Sbjct: 1192 EETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA----KANLDKNKQTLEKENAD--LAG 1245
Query: 111 DLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLES 170
+LR+ + K + A+ E Q+ + + R + ++ + + ML
Sbjct: 1246 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1305
Query: 171 --GKPSIFTSDIISDS---QITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQ 225
GK D+ S S Q T++ L E E+R K + + T +R+L E + ++ +
Sbjct: 1306 AEGKAIKLAKDVASLSSQLQDTQELLQE-ETRQK--LNVSTKLRQLEEERNSLQDQLDEE 1362
Query: 226 GEMINNIERNVMNATDYVEHAKEE 249
E N+ER++ + +K++
Sbjct: 1363 MEAKQNLERHISTLNIQLSDSKKK 1386
Score = 30.8 bits (68), Expect = 1.4
Identities = 31/198 (15%), Positives = 75/198 (37%), Gaps = 24/198 (12%)
Query: 36 VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAI 95
+E + + + K TQ E++ + S +++LE NKE +R+KL +
Sbjct: 1759 MEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE-------LRSKLHEM 1811
Query: 96 EQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEIT 155
E + +++ +I + + V + E A +++ K + L++
Sbjct: 1812 EGAVKSKFKSTIAALEAKIAQLEEQV-----EQEAREKQAATKSLKQKDKKLKEILLQVE 1866
Query: 156 GRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMF 215
++ +E E G + +Q ++E ++ ++ + R+L
Sbjct: 1867 DERKMAEQYKEQAEKGNARV------------KQLKRQLEEAEEESQRINANRRKLQREL 1914
Query: 216 MDMAMFVETQGEMINNIE 233
+ E G +N ++
Sbjct: 1915 DEATESNEAMGREVNALK 1932
Score = 29.6 bits (65), Expect = 3.2
Identities = 38/250 (15%), Positives = 102/250 (40%), Gaps = 29/250 (11%)
Query: 25 KDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKT 84
K+ + V ++ N ++ ++ +K ++ N K +E + E ++
Sbjct: 1429 KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREK 1488
Query: 85 ANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERS 144
K + +A+E++ + E RT + +L + + ++ ++ E
Sbjct: 1489 ETKALSLARALEEALEAKEELERT----------NKMLKAEMEDLVSSKDDVGKNVHELE 1538
Query: 145 KGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQAL-----NEIESRHK 199
K + + ++ T +ELE+ L++ T D ++ QAL ++++R +
Sbjct: 1539 KSKRALETQMEEMKTQLEELEDELQA------TEDAKLRLEVNMQALKGQFERDLQARDE 1592
Query: 200 DIMKLETSI-RELHEMFMDM-------AMFVETQGEMINNIERNVMNATDYVEHAKEETK 251
+ + R+LHE ++ A+ + ++ +++ + A ++ +E K
Sbjct: 1593 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1652
Query: 252 KAIKYQSKAR 261
+ K Q++ +
Sbjct: 1653 QLRKLQAQMK 1662
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 49.3 bits (116), Expect = 4e-06
Identities = 45/227 (19%), Positives = 99/227 (43%), Gaps = 16/227 (7%)
Query: 37 EEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKE------IKKTANKIRA 90
EE++ ++ ++ +E+ + ++ + EG I + EDL+ E +K +
Sbjct: 1090 EELQAALARLD---DEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGE 1146
Query: 91 KLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQR 150
+L+A++ + T +LR +R Q + +K ++ +EAQ +E + Q
Sbjct: 1147 ELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQV--QEMRQKHAQA 1204
Query: 151 QLEITGRTTTDDELEEMLESGKPSI--FTSDIISDSQITRQALNEIESRHKDIMKLETSI 208
E+T + + L+ K ++ +D+ + ++ QA E+E + K KLE +
Sbjct: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKK---KLEAQV 1261
Query: 209 RELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIK 255
+EL D + ++ ++ V + T + A+ + K K
Sbjct: 1262 QELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1308
Score = 36.2 bits (82), Expect = 0.034
Identities = 50/279 (17%), Positives = 121/279 (43%), Gaps = 56/279 (20%)
Query: 29 MDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKI 88
+++ Q+E+ + + + + + ++K ++ + G+ K+E+E K+++ ++
Sbjct: 1205 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 1264
Query: 89 RAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSV----------------LSRKFVEAMAE 132
++K E++ R ++ ++ + Q+ V L++ ++
Sbjct: 1265 QSKCSDGERA--------RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQ 1316
Query: 133 YNEAQTLFRERSKGRIQ-----RQLEITGRTTTDDELEEMLESG---KPSIFTSDI-ISD 183
+ Q L +E ++ ++ RQLE R + D+L+E +E+ + I T +I +SD
Sbjct: 1317 LQDTQELLQEETRQKLNVSTKLRQLE-EERNSLQDQLDEEMEAKQNLERHISTLNIQLSD 1375
Query: 184 SQ-------ITRQALNEIESR-HKDIM--------------KLETSIRELHEMFMDMAMF 221
S+ T +AL E + R K+I KLE + L + D+ +
Sbjct: 1376 SKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVD 1435
Query: 222 VETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKA 260
++ Q ++++N+E+ + K + K + +A
Sbjct: 1436 LDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRA 1474
Score = 35.4 bits (80), Expect = 0.058
Identities = 51/263 (19%), Positives = 104/263 (39%), Gaps = 38/263 (14%)
Query: 29 MDDFFHQVEEIRNSIDKITQYVEEVKKN-----------HSIILSAPNPEGKIKEELEDL 77
M DF ++E+ R S D+I +E +K + +A + E E+L
Sbjct: 1654 MKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEEL 1713
Query: 78 NKEIKKTAN----------KIRAKLKAIEQSFDQDESGNRTSVDLRIRRT--QHSVLSRK 125
+E+ + + ++ A++ +E+ ++E GN ++ R+R+ Q LS +
Sbjct: 1714 AEELASSLSGRNALQDEKRRLEARIAQLEEEL-EEEQGNMEAMSDRVRKATQQAEQLSNE 1772
Query: 126 FV--EAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISD 183
+ A+ NE+ ER ++ +L E+E ++S S +
Sbjct: 1773 LATERSTAQKNESARQQLERQNKELRSKLH---------EMEGAVKSKFKSTIAALEAKI 1823
Query: 184 SQITRQALNEIESRHKDIMKLETSIRELHEMFM---DMAMFVETQGEMINNIERNVMNAT 240
+Q+ Q E + L+ ++L E+ + D E E V
Sbjct: 1824 AQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLK 1883
Query: 241 DYVEHAKEETKKAIKYQSKARRK 263
+E A+EE+++ + K +R+
Sbjct: 1884 RQLEEAEEESQRINANRRKLQRE 1906
Score = 31.2 bits (69), Expect = 1.1
Identities = 39/204 (19%), Positives = 88/204 (43%), Gaps = 14/204 (6%)
Query: 51 EEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSV 110
EE + + + + + EEL + ++ K+ +A L +Q+ +++ + +
Sbjct: 1185 EETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA----KANLDKNKQTLEKENAD--LAG 1238
Query: 111 DLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLES 170
+LR+ + K + A+ E Q+ + + R + ++ + + ML
Sbjct: 1239 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNE 1298
Query: 171 --GKPSIFTSDIISDS---QITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQ 225
GK D+ S S Q T++ L E E+R K + + T +R+L E + ++ +
Sbjct: 1299 AEGKAIKLAKDVASLSSQLQDTQELLQE-ETRQK--LNVSTKLRQLEEERNSLQDQLDEE 1355
Query: 226 GEMINNIERNVMNATDYVEHAKEE 249
E N+ER++ + +K++
Sbjct: 1356 MEAKQNLERHISTLNIQLSDSKKK 1379
Score = 30.8 bits (68), Expect = 1.4
Identities = 31/198 (15%), Positives = 75/198 (37%), Gaps = 24/198 (12%)
Query: 36 VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAI 95
+E + + + K TQ E++ + S +++LE NKE +R+KL +
Sbjct: 1752 MEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE-------LRSKLHEM 1804
Query: 96 EQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEIT 155
E + +++ +I + + V + E A +++ K + L++
Sbjct: 1805 EGAVKSKFKSTIAALEAKIAQLEEQV-----EQEAREKQAATKSLKQKDKKLKEILLQVE 1859
Query: 156 GRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMF 215
++ +E E G + +Q ++E ++ ++ + R+L
Sbjct: 1860 DERKMAEQYKEQAEKGNARV------------KQLKRQLEEAEEESQRINANRRKLQREL 1907
Query: 216 MDMAMFVETQGEMINNIE 233
+ E G +N ++
Sbjct: 1908 DEATESNEAMGREVNALK 1925
Score = 29.6 bits (65), Expect = 3.2
Identities = 38/250 (15%), Positives = 102/250 (40%), Gaps = 29/250 (11%)
Query: 25 KDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKT 84
K+ + V ++ N ++ ++ +K ++ N K +E + E ++
Sbjct: 1422 KNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREK 1481
Query: 85 ANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERS 144
K + +A+E++ + E RT + +L + + ++ ++ E
Sbjct: 1482 ETKALSLARALEEALEAKEELERT----------NKMLKAEMEDLVSSKDDVGKNVHELE 1531
Query: 145 KGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQAL-----NEIESRHK 199
K + + ++ T +ELE+ L++ T D ++ QAL ++++R +
Sbjct: 1532 KSKRALETQMEEMKTQLEELEDELQA------TEDAKLRLEVNMQALKGQFERDLQARDE 1585
Query: 200 DIMKLETSI-RELHEMFMDM-------AMFVETQGEMINNIERNVMNATDYVEHAKEETK 251
+ + R+LHE ++ A+ + ++ +++ + A ++ +E K
Sbjct: 1586 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1645
Query: 252 KAIKYQSKAR 261
+ K Q++ +
Sbjct: 1646 QLRKLQAQMK 1655
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 48.9 bits (115), Expect = 5e-06
Identities = 66/283 (23%), Positives = 122/283 (43%), Gaps = 48/283 (16%)
Query: 3 DRLPDLTACRKNDDGDTVVVVEKDHFMD---------------DFFHQVEEIRNSIDKIT 47
D+L + D D V++EK H M+ D + E++N +K+
Sbjct: 1018 DKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKL- 1076
Query: 48 QYVEEVKKNHSIILSAPNPEGKIK---EELEDLNKEIKKTANKIRAKLKAIEQSFDQDES 104
VEE K S IL+ N K E++E L K + T ++ +LK++++ +++++
Sbjct: 1077 --VEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQ 1134
Query: 105 GNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDEL 164
L + SV +AE+ + + F E+ G I+ L ++E
Sbjct: 1135 TVTKLHQLLENQKNSSV-------PLAEHLQIKEAF-EKEVGIIKASLR-----EKEEES 1181
Query: 165 EEMLESGKPSIFTSDIISDSQITRQALNEIESRH-KDIMK-------LETSIRELHEMFM 216
+ +E S + S+ Q T+QAL ++E+R D+ K LET I L+E
Sbjct: 1182 QNKMEE------VSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLA 1235
Query: 217 DMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSK 259
++ E E + + ++ ++A D E ++ IK Q +
Sbjct: 1236 NLNRKYEEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQKE 1278
Score = 33.9 bits (76), Expect = 0.17
Identities = 48/235 (20%), Positives = 93/235 (39%), Gaps = 38/235 (16%)
Query: 51 EEVKKNHSIILSAPNPEG-KIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQ-------- 101
EEVK + L+ N E +K++ ED+N+E K +K + +E + +Q
Sbjct: 853 EEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISL 912
Query: 102 -DESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQ----TLFRE-----RSKGRIQRQ 151
+ +S+ +R+ Q S E +A Y + Q TL E + IQ
Sbjct: 913 AEHEAKMSSLSQSMRKVQDS-----NAEILANYRKGQEEIVTLHAEIKAQKKELDTIQEC 967
Query: 152 LEITGR------------TTTDDELEEML--ESGKPSIFTSDIISDSQITRQALNEIESR 197
+++ T+ EL++ L ++ K S+ ++ + Q + EI +
Sbjct: 968 IKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTL 1027
Query: 198 HKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKK 252
KD+ I + HEM ++ + + + ++ + + E EE K
Sbjct: 1028 QKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAK 1082
Score = 30.8 bits (68), Expect = 1.4
Identities = 57/291 (19%), Positives = 111/291 (38%), Gaps = 79/291 (27%)
Query: 37 EEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIE 96
+++ K + EEVKKN K+E + L KEI +R K IE
Sbjct: 994 DQLSEQTQKYSVSEEEVKKN--------------KQENDKLKKEIFTLQKDLRDKTVLIE 1039
Query: 97 QSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEA------MAEYNEAQT------------ 138
+S + + + +R + +L Q LS+K+ E + E N QT
Sbjct: 1040 KSHEMERALSRKTDEL---NKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQK 1096
Query: 139 ---------LFRERSKGRI----------QRQLEITGRTTTDDELEEMLESGKPS----- 174
++ G I QR E +T T +L ++LE+ K S
Sbjct: 1097 QHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVT--KLHQLLENQKNSSVPLA 1154
Query: 175 -------IFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMF--------MDMA 219
F ++ R+ E +++ +++ KL++ ++ + +D++
Sbjct: 1155 EHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLS 1214
Query: 220 MFVETQGEM---INNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWII 267
+ T+ ++ I+++ + N E EE A K + A+ +K ++
Sbjct: 1215 KYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAKDEKELL 1265
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 48.9 bits (115), Expect = 5e-06
Identities = 66/283 (23%), Positives = 122/283 (43%), Gaps = 48/283 (16%)
Query: 3 DRLPDLTACRKNDDGDTVVVVEKDHFMD---------------DFFHQVEEIRNSIDKIT 47
D+L + D D V++EK H M+ D + E++N +K+
Sbjct: 1031 DKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKL- 1089
Query: 48 QYVEEVKKNHSIILSAPNPEGKIK---EELEDLNKEIKKTANKIRAKLKAIEQSFDQDES 104
VEE K S IL+ N K E++E L K + T ++ +LK++++ +++++
Sbjct: 1090 --VEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQ 1147
Query: 105 GNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDEL 164
L + SV +AE+ + + F E+ G I+ L ++E
Sbjct: 1148 TVTKLHQLLENQKNSSV-------PLAEHLQIKEAF-EKEVGIIKASLR-----EKEEES 1194
Query: 165 EEMLESGKPSIFTSDIISDSQITRQALNEIESRH-KDIMK-------LETSIRELHEMFM 216
+ +E S + S+ Q T+QAL ++E+R D+ K LET I L+E
Sbjct: 1195 QNKMEE------VSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLA 1248
Query: 217 DMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSK 259
++ E E + + ++ ++A D E ++ IK Q +
Sbjct: 1249 NLNRKYEEVCEEVLHAKKKEISAKDEKELLHFSIEQEIKDQKE 1291
Score = 33.9 bits (76), Expect = 0.17
Identities = 48/235 (20%), Positives = 93/235 (39%), Gaps = 38/235 (16%)
Query: 51 EEVKKNHSIILSAPNPEG-KIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQ-------- 101
EEVK + L+ N E +K++ ED+N+E K +K + +E + +Q
Sbjct: 866 EEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISL 925
Query: 102 -DESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQ----TLFRE-----RSKGRIQRQ 151
+ +S+ +R+ Q S E +A Y + Q TL E + IQ
Sbjct: 926 AEHEAKMSSLSQSMRKVQDS-----NAEILANYRKGQEEIVTLHAEIKAQKKELDTIQEC 980
Query: 152 LEITGR------------TTTDDELEEML--ESGKPSIFTSDIISDSQITRQALNEIESR 197
+++ T+ EL++ L ++ K S+ ++ + Q + EI +
Sbjct: 981 IKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTL 1040
Query: 198 HKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKK 252
KD+ I + HEM ++ + + + ++ + + E EE K
Sbjct: 1041 QKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAK 1095
Score = 30.8 bits (68), Expect = 1.4
Identities = 57/291 (19%), Positives = 111/291 (38%), Gaps = 79/291 (27%)
Query: 37 EEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIE 96
+++ K + EEVKKN K+E + L KEI +R K IE
Sbjct: 1007 DQLSEQTQKYSVSEEEVKKN--------------KQENDKLKKEIFTLQKDLRDKTVLIE 1052
Query: 97 QSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEA------MAEYNEAQT------------ 138
+S + + + +R + +L Q LS+K+ E + E N QT
Sbjct: 1053 KSHEMERALSRKTDEL---NKQLKDLSQKYTEVKNVKEKLVEENAKQTSEILAVQNLLQK 1109
Query: 139 ---------LFRERSKGRI----------QRQLEITGRTTTDDELEEMLESGKPS----- 174
++ G I QR E +T T +L ++LE+ K S
Sbjct: 1110 QHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVT--KLHQLLENQKNSSVPLA 1167
Query: 175 -------IFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMF--------MDMA 219
F ++ R+ E +++ +++ KL++ ++ + +D++
Sbjct: 1168 EHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLETREVVDLS 1227
Query: 220 MFVETQGEM---INNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWII 267
+ T+ ++ I+++ + N E EE A K + A+ +K ++
Sbjct: 1228 KYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEISAKDEKELL 1278
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 47.0 bits (110), Expect = 2e-05
Identities = 48/270 (17%), Positives = 115/270 (42%), Gaps = 35/270 (12%)
Query: 23 VEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNK--- 79
++ H D+FFH+ E++ I+++ K+ ++ K+K EL LNK
Sbjct: 367 MDAQHIKDEFFHEREDLEFKINELLL----AKEEQGCVIE------KLKSELAGLNKQFC 416
Query: 80 --------EIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIR--RTQHSVLSRKFVEA 129
E++ + + ++ + ++F D + ++ I+ + Q L ++ EA
Sbjct: 417 YTVEQHNREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEA 476
Query: 130 MAEYNEAQTLFR------ERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISD 183
+ Y + + S G+I ++ E + D + E+ + + + D + +
Sbjct: 477 ILNYESLREIMEILQTELGESAGKISQEFESMKQQQASD-VHELQQKLRTAFTEKDALLE 535
Query: 184 SQITRQALNE-IESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNAT-- 240
+ Q NE + S+ + + +LE +I+ L E + + + M+ +E + + T
Sbjct: 536 TVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEE 595
Query: 241 --DYVEHAKEETKKAIKYQSKARRKKWIII 268
D++ K ++ + K R++ +I+
Sbjct: 596 KDDFINKLKNSHEEMDNFHKKCEREERLIL 625
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 43.9 bits (102), Expect = 2e-04
Identities = 49/255 (19%), Positives = 119/255 (46%), Gaps = 40/255 (15%)
Query: 34 HQVEEIRNSIDKITQYVEEVKKNHSIILSAPNP-EGKIKEELEDLNKE-------IKKTA 85
++++E+ +I + E + + + + P E ++ +E E L KE +K
Sbjct: 1957 NRLQELEAEQQQIQEERELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVR 2016
Query: 86 NKIRAKLKAIEQSFDQD-----ESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLF 140
+ ++ ++KA+E ++ E + +L R Q+ L ++ +E M ++ + Q +
Sbjct: 2017 DDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQ-LEKMRKFLDEQAID 2075
Query: 141 RERSKG-------RIQRQLEITGR--TTTDDELEEMLESGKPSIFTSDIISDSQITRQAL 191
RE + ++++QL++ R ++ + E+ + +D S+ ++++ L
Sbjct: 2076 REHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQL 2135
Query: 192 N-EIESRHKDIMKLETSIRELHEMFM--------------DMAMFVETQGE--MINNIER 234
+I+ R+++I KLE +REL + + ++++ V+ Q E I+ E+
Sbjct: 2136 QRDIQERNEEIEKLEFRVRELEQALLVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEK 2195
Query: 235 NVMNATDYVEHAKEE 249
+ N + +E +EE
Sbjct: 2196 EITNLEEQLEQFREE 2210
Score = 32.3 bits (72), Expect = 0.50
Identities = 37/157 (23%), Positives = 71/157 (45%), Gaps = 18/157 (11%)
Query: 69 KIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVD------LRIRRT----- 117
+ +EELE+ N+E+++ ++ + K + E N+ D L I+ +
Sbjct: 2206 QFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMST 2265
Query: 118 --QHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSI 175
QH VL KF + + E E + ++Q+QL+IT +E E++ + I
Sbjct: 2266 QDQH-VLFGKFAQIIQE-KEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQI 2323
Query: 176 FTSDIISDSQ-ITRQALNEIESRHKDIMKLETSIREL 211
++SD + + R EIE ++ I KL+ + +
Sbjct: 2324 --ECLMSDQECVKRNREEEIEQLNEVIEKLQQELANI 2358
>gi|237858621 polyamine modulated factor 1 binding protein 1 isoform
b [Homo sapiens]
Length = 882
Score = 43.1 bits (100), Expect = 3e-04
Identities = 44/241 (18%), Positives = 112/241 (46%), Gaps = 22/241 (9%)
Query: 24 EKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKK 83
EKD + + ++ +++NS+ K + +E+ + A E +KE +D +KE +
Sbjct: 260 EKDEMLQELEKKLTQVQNSLLKKEKELEKQQ------CMATELEMTVKEAKQDKSKEAEC 313
Query: 84 TANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRER 143
A ++A+++ ++ S ++ + R + + + + L+ +E + L ++
Sbjct: 314 KA--LQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQ 371
Query: 144 SKGRIQ---RQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKD 200
IQ R+L++ + ++ E E+ + + ++ +AL ++E+ K+
Sbjct: 372 KADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLEL-------SEALRKLENSDKE 424
Query: 201 IMKLETSIRELHEMFMDMAMFVE----TQGEMINNIERNVMNATDYVEHAKEETKKAIKY 256
+L+ ++ E DM ++ QG + +E ++ AT +E +E+ KK+ ++
Sbjct: 425 KRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLKKSKEH 484
Query: 257 Q 257
+
Sbjct: 485 E 485
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 43.1 bits (100), Expect = 3e-04
Identities = 44/241 (18%), Positives = 112/241 (46%), Gaps = 22/241 (9%)
Query: 24 EKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKK 83
EKD + + ++ +++NS+ K + +E+ + A E +KE +D +KE +
Sbjct: 405 EKDEMLQELEKKLTQVQNSLLKKEKELEKQQ------CMATELEMTVKEAKQDKSKEAEC 458
Query: 84 TANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRER 143
A ++A+++ ++ S ++ + R + + + + L+ +E + L ++
Sbjct: 459 KA--LQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQ 516
Query: 144 SKGRIQ---RQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKD 200
IQ R+L++ + ++ E E+ + + ++ +AL ++E+ K+
Sbjct: 517 KADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLEL-------SEALRKLENSDKE 569
Query: 201 IMKLETSIRELHEMFMDMAMFVE----TQGEMINNIERNVMNATDYVEHAKEETKKAIKY 256
+L+ ++ E DM ++ QG + +E ++ AT +E +E+ KK+ ++
Sbjct: 570 KRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLKKSKEH 629
Query: 257 Q 257
+
Sbjct: 630 E 630
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 43.1 bits (100), Expect = 3e-04
Identities = 57/242 (23%), Positives = 108/242 (44%), Gaps = 29/242 (11%)
Query: 35 QVEEIRNSIDKITQYV-EEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANK----IR 89
Q EE+R +K + EE++K S K+K E+++ K I+KT+ + ++
Sbjct: 397 QGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQ 456
Query: 90 AKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQ 149
+L ++Q + ++++ L+RK E + + F+E+ K ++
Sbjct: 457 QELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALE 516
Query: 150 RQ----LEITGRTTTDDELE-EMLESGKPSIFTS------DIISDSQITRQALNEIESRH 198
+ L+I+ + L E LE K +I T D+ +++ R + E+ES
Sbjct: 517 KSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELES-- 574
Query: 199 KDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQS 258
LE S++E D+A+ +E + +N E VM VE K E +++K+Q
Sbjct: 575 ----SLEKSLQENKNQSKDLAVHLEAEKNK-HNKEITVM-----VEKHKTEL-ESLKHQQ 623
Query: 259 KA 260
A
Sbjct: 624 DA 625
Score = 35.4 bits (80), Expect = 0.058
Identities = 40/191 (20%), Positives = 84/191 (43%), Gaps = 17/191 (8%)
Query: 24 EKDHFMDD----FFHQVEEIRN-SIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLN 78
EK+ + D F +EE+ +++K+ E++ S + K++EEL L
Sbjct: 652 EKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLK 711
Query: 79 KEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMA-EYNEAQ 137
+ K ++ AK+ D+ ++ ++ VD I+ +H V ++ +A+ + N+ +
Sbjct: 712 DQTDKMKQELEAKM-------DEQKNHHQQQVDSIIK--EHEVSIQRTEKALKDQINQLE 762
Query: 138 TLFRERSKGRIQRQLEITGRTTTDDELEEMLE--SGKPSIFTSDIISDSQITRQALNEIE 195
L +ER K + Q + E L+ S K +F S + + T+ ++
Sbjct: 763 LLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLA 822
Query: 196 SRHKDIMKLET 206
+ ++ LET
Sbjct: 823 QLQQKLLDLET 833
Score = 32.0 bits (71), Expect = 0.65
Identities = 49/289 (16%), Positives = 115/289 (39%), Gaps = 53/289 (18%)
Query: 12 RKNDDGDTVVVVEKDHFMDDFFHQVEE-----IRNSIDKITQYVEEVKK-NHSIILSAPN 65
R+ + ++ +K +D H + E +N K+ + ++ K+ ++ +
Sbjct: 917 REGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLD 976
Query: 66 PEGKIKEELEDLNKEIKKTANKIRAKLKAIEQS-----------FDQDESGNRTSVDLRI 114
E K+K+ELE+ E+ + + AK+ + Q+ + ++ S+
Sbjct: 977 QEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVH 1036
Query: 115 RRTQHSVLS------RKFVEAMAEYNEAQTLFRERSKGRIQRQLEITG------------ 156
RR + V+S + E + E +E Q +E+ +++++ + G
Sbjct: 1037 RRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITW 1096
Query: 157 -------RTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIR 209
+ TT +EL+E L+ + S + + D + L ++E + L S++
Sbjct: 1097 LKEEGVKQDTTLNELQEQLK--QKSAHVNSLAQDETKLKAHLEKLE------VDLNKSLK 1148
Query: 210 E---LHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIK 255
E L E +++ M E ++ + + + + K +K+ K
Sbjct: 1149 ENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNK 1197
Score = 31.6 bits (70), Expect = 0.84
Identities = 45/243 (18%), Positives = 107/243 (44%), Gaps = 21/243 (8%)
Query: 21 VVVEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKN-HSIILSAPNPEGK------IKEE 73
+V EK+ + +Q + ITQ +E+ +N +++ L + K + ++
Sbjct: 1316 LVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQ 1375
Query: 74 LEDLNKEIKK--TANKIRAKLKAIEQSFDQDESGNRTSV-DLRIRRTQHSVLSRKFVEAM 130
L DLN +++ + ++ A + ++ + +D+++ V DL + LS++ + A+
Sbjct: 1376 LTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFK---VDTLSKEKISAL 1432
Query: 131 AEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQA 190
+ ++ F E K + Q T T EL+ LE + D + ++
Sbjct: 1433 EQVDDWSNKFSEWKK---KAQSRFTQHQNTVKELQIQLELKSKEAYEKD--EQINLLKEE 1487
Query: 191 LNEIESRHKDIMK--LETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKE 248
L++ +++ D +K +E ++ + ++ +++Q I +E ++ T +E E
Sbjct: 1488 LDQ-QNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNE 1546
Query: 249 ETK 251
K
Sbjct: 1547 VLK 1549
Score = 28.9 bits (63), Expect = 5.5
Identities = 30/144 (20%), Positives = 66/144 (45%), Gaps = 2/144 (1%)
Query: 53 VKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDL 112
VK+ IL+ N +K ELE KE++ +++K + ++ D+ ES + +
Sbjct: 1580 VKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAE 1639
Query: 113 RIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRI-QRQLEITGRTTTDDELEEMLESG 171
R+ + + + K + +++ E + +++ ++ + + ++ R LEE L+S
Sbjct: 1640 LKRKAEQKIAAIK-KQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSV 1698
Query: 172 KPSIFTSDIISDSQITRQALNEIE 195
+ S + I+ S A E E
Sbjct: 1699 ESSQSETLIVPRSAKNVAAYTEQE 1722
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 43.1 bits (100), Expect = 3e-04
Identities = 49/226 (21%), Positives = 95/226 (42%), Gaps = 38/226 (16%)
Query: 72 EELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSV----DLRIRRTQHSVLSRKFV 127
EELE+ NK ++K + L+ + + E GN + + +LR R + +
Sbjct: 343 EELEETNKNLQKAEEE----LQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEIT 398
Query: 128 EAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLES---------------GK 172
+ ++ E + +E + +LE+ ELE++ E+ K
Sbjct: 399 KTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEK 458
Query: 173 PSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIR-ELHEMFMDMAMFVETQGEMINN 231
T D++++ ++ + + E+E + K E S++ +L ++ M V+ + M+
Sbjct: 459 EKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEK 518
Query: 232 I---ERNV--MNATDYVEHAK---------EETKKAIKYQSKARRK 263
I ER V +N VE K EE+KK +K +S+ K
Sbjct: 519 IKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEK 564
Score = 39.3 bits (90), Expect = 0.004
Identities = 44/218 (20%), Positives = 96/218 (44%), Gaps = 13/218 (5%)
Query: 13 KNDDGDTVVVVEKDHFM----DDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEG 68
K+DD ++ E++ + +Q + + + ++ + +E+ K S L +
Sbjct: 196 KSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQ 255
Query: 69 KIKEELEDLNKEIKKTANKIRA---KLKAIEQSFDQDESGN-RTSVDLRIRRTQHSVLSR 124
E+L +++++ K+R KLKAI +D + VD + ++ S
Sbjct: 256 MHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHE 315
Query: 125 KFVEAMAEYNEAQTLFRERSKGRIQR--QLEITGRTT--TDDELEEMLES-GKPSIFTSD 179
+ +A R + G QR +LE T + ++EL+E+ + K S
Sbjct: 316 EMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSS 375
Query: 180 IISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMD 217
++++ + R+ + E+E + ++I K E+ REL + +
Sbjct: 376 LMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQE 413
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
(with transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 43.1 bits (100), Expect = 3e-04
Identities = 42/215 (19%), Positives = 100/215 (46%), Gaps = 22/215 (10%)
Query: 33 FHQVEEI--------RNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKT 84
FH+ +EI I + Q +EE KKN SA + EE + L ++K+
Sbjct: 700 FHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFT---ALSEERDQLLSQVKEL 756
Query: 85 A--NKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRE 142
+ ++RA++K +E + + E R + +T H L + + +++ +++ + E
Sbjct: 757 SMVTELRAQVKQLEMNLAEAERQRRLDYE---SQTAHDNLLTEQIHSLSIEAKSKDVKIE 813
Query: 143 RSKGRIQR-QLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDI 201
+ + QL+ + ++T L+ L++ + S+++ ++ R +++E + +
Sbjct: 814 VLQNELDDVQLQFSEQSTLIRSLQSQLQNKE-----SEVLEGAERVRHISSKVEELSQAL 868
Query: 202 MKLETSIRELHEMFMDMAMFVETQGEMINNIERNV 236
+ E I ++ ++ ++ VET + I ++ V
Sbjct: 869 SQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQV 903
Score = 37.7 bits (86), Expect = 0.012
Identities = 65/267 (24%), Positives = 115/267 (43%), Gaps = 51/267 (19%)
Query: 18 DTVVVVEKDHF-----MDDFFHQVEEIRNSIDKITQYVEEVKKNH-SIIL-------SAP 64
+T+ ++K++ +D F + ++N D+I +++++ H SIIL A
Sbjct: 2443 ETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAA 2502
Query: 65 NPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVD------LRIRRTQ 118
K+KEE+ L + N AKL A + +D + T D L ++ Q
Sbjct: 2503 AENNKLKEEIRGLRSHM-DDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQ 2561
Query: 119 HSVLSRKFV---EAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSI 175
+ L K+ E + E EA R RS +Q + + +L + +ES K SI
Sbjct: 2562 NKELENKYAKLEEKLKESEEANEDLR-RSFNALQEEKQ---------DLSKEIESLKVSI 2611
Query: 176 FTSDIISDSQITRQ--ALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIE 233
SQ+TRQ AL E + +L+ E+H + A+F +Q + I +E
Sbjct: 2612 --------SQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRL---SALFSSSQ-KRIAELE 2659
Query: 234 RNVM----NATDYVEHAKEETKKAIKY 256
++ A V +++ KK +K+
Sbjct: 2660 EELVCVQKEAAKKVGEIEDKLKKELKH 2686
Score = 32.3 bits (72), Expect = 0.50
Identities = 42/248 (16%), Positives = 104/248 (41%), Gaps = 23/248 (9%)
Query: 29 MDDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKI 88
++++ Q+++++ ++I EE +KN + N + + ++ + E+K ++
Sbjct: 1835 INNYLQQIDQLK---ERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEV 1891
Query: 89 RAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYN-EAQTLFRERSKGR 147
K+ + Q ++ S R + + L + + +AE N ++ + +
Sbjct: 1892 -TKMNLLNQQIQEELS--RVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQ 1948
Query: 148 IQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKD------I 201
I+ +L + + LE K + +S+I ++ L +I+ K+
Sbjct: 1949 IKNEL-LESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHA 2007
Query: 202 MKLETSIRELHEMFMDMAMFVETQGEMINNIERNVMNATDYV--------EHAKEETKKA 253
+L+ ++E + + E I+ +ER V A ++V E KE +A
Sbjct: 2008 KELQELLKEKQQEVKQLQKDCIRYQEKISALERTV-KALEFVQTESQKDLEITKENLAQA 2066
Query: 254 IKYQSKAR 261
++++ KA+
Sbjct: 2067 VEHRKKAQ 2074
Score = 30.8 bits (68), Expect = 1.4
Identities = 48/275 (17%), Positives = 100/275 (36%), Gaps = 52/275 (18%)
Query: 31 DFFHQVEEIRNSIDKITQYV--------------------EEVKKNHSIILSAPNPEGKI 70
D ++E ++ SI ++T+ V EEV + ++ S+ ++
Sbjct: 2599 DLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAEL 2658
Query: 71 KEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAM 130
+EEL + KE K +I KLK + D R + R + L+R VE
Sbjct: 2659 EEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERV--AELARDLVEM- 2715
Query: 131 AEYNEAQTLFRERSKGRIQRQLEITGRTTTD-----------------------DELEEM 167
E + L + + Q++ GR+ + EL ++
Sbjct: 2716 ----EQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQL 2771
Query: 168 LESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGE 227
E G + ++S++ + + E H + KL + E + ++ +E
Sbjct: 2772 KEQGLLNRERDALLSETAFSMNSTEENSLSH--LEKLNQQLLSKDEQLLHLSSQLEDSYN 2829
Query: 228 MINNIERNVMNATDYVEHAKEETKKAIKYQSKARR 262
+ + + + + + +H E +K K + +R
Sbjct: 2830 QVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQR 2864
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 41.2 bits (95), Expect = 0.001
Identities = 42/227 (18%), Positives = 95/227 (41%), Gaps = 16/227 (7%)
Query: 37 EEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKE------IKKTANKIRA 90
EE++ ++ ++ EE + + + E +I E EDL E +K +
Sbjct: 1083 EELQAALARVE---EEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGE 1139
Query: 91 KLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQR 150
+L+A++ + +LR +R Q + +K +E A+ +EAQ +E + Q
Sbjct: 1140 ELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQ--IQEMRQKHSQA 1197
Query: 151 QLEITGRTTTDDELEEMLESGKPSIFT--SDIISDSQITRQALNEIESRHKDIMKLETSI 208
E+ + ++ LE K ++ ++ ++ ++ Q + E + K K+E +
Sbjct: 1198 VEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRK---KVEAQL 1254
Query: 209 RELHEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIK 255
+EL F + + + ++ + N T + + ++ K K
Sbjct: 1255 QELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTK 1301
Score = 31.2 bits (69), Expect = 1.1
Identities = 38/168 (22%), Positives = 72/168 (42%), Gaps = 15/168 (8%)
Query: 69 KIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVE 128
+++E+L+ E+ A ++RA+L A +Q ++ V+ R QH +K ++
Sbjct: 884 QLQEQLQ-AETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ 942
Query: 129 AMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITR 188
+ E Q E R + QLE + TT+ +L+++ E II + Q +
Sbjct: 943 QNIQELEEQ--LEEEESARQKLQLE---KVTTEAKLKKLEE--------EQIILEDQNCK 989
Query: 189 QALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNV 236
A E + I + T++ E E +A MI ++E +
Sbjct: 990 LA-KEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERL 1036
Score = 30.8 bits (68), Expect = 1.4
Identities = 42/227 (18%), Positives = 84/227 (37%), Gaps = 51/227 (22%)
Query: 2 RDRLPDLTACRKNDDGDTVVVVEKDHFMDDFFHQVEE-----------IRNSIDKITQYV 50
RD L D A N G + +E+ ++ Q+EE I + + K +
Sbjct: 1703 RDELADEIA---NSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQI 1759
Query: 51 EEVKKNHSIILSAPNPEGKIKEELEDLNKEIK--------KTANKIRAKLKAIEQSFDQ- 101
+++ + ++ S +++LE NKE+K +K +A + A+E Q
Sbjct: 1760 DQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQL 1819
Query: 102 -----DESGNRTSVDLRIRRTQHSV-----------------------LSRKFVEAMAEY 133
+E+ R + ++RRT+ + S + + +
Sbjct: 1820 EEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQL 1879
Query: 134 NEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFTSDI 180
EA+ + + R + Q E+ T T D + + S K + D+
Sbjct: 1880 EEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDL 1926
Score = 30.0 bits (66), Expect = 2.5
Identities = 41/190 (21%), Positives = 75/190 (39%), Gaps = 35/190 (18%)
Query: 30 DDFFHQVEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANKIR 89
DD V E+ S + Q VEE+K EELED + + ++
Sbjct: 1514 DDVGKSVHELEKSKRALEQQVEEMKTQ--------------LEELEDELQATEDAKLRLE 1559
Query: 90 AKLKAIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQ 149
L+A++ F++D G R + S +K + EA E R Q
Sbjct: 1560 VNLQAMKAQFERDLQG----------RDEQSEEKKKQLVRQVREMEA-----ELEDERKQ 1604
Query: 150 RQLEITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNEIESRHKDIMKLETSIR 209
R + + R + +L+++ + I +++ D I + L +++++ KD M+ R
Sbjct: 1605 RSMAVAARKKLEMDLKDL----EAHIDSANKNRDEAI--KQLRKLQAQMKDCMRELDDTR 1658
Query: 210 ELHEMFMDMA 219
E + A
Sbjct: 1659 ASREEILAQA 1668
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.347
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,972,412
Number of Sequences: 37866
Number of extensions: 353177
Number of successful extensions: 2953
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 331
Number of HSP's that attempted gapping in prelim test: 2373
Number of HSP's gapped (non-prelim): 856
length of query: 288
length of database: 18,247,518
effective HSP length: 101
effective length of query: 187
effective length of database: 14,423,052
effective search space: 2697110724
effective search space used: 2697110724
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.