Guide to the Human Genome
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Search of human proteins with 37537704

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|37537704 glutaredoxin 2 isoform 2 [Homo sapiens]
         (164 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|37537704 glutaredoxin 2 isoform 2 [Homo sapiens]                   332   9e-92
gi|21361507 glutaredoxin 2 isoform 1 [Homo sapiens]                   261   2e-70
gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens]          65   2e-11
gi|169646776 glutaredoxin (thioltransferase) [Homo sapiens]            62   3e-10
gi|4504025 glutaredoxin (thioltransferase) [Homo sapiens]              62   3e-10
gi|122937349 glutaredoxin, cysteine rich 1 [Homo sapiens]              41   5e-04
gi|95113651 glutaredoxin 3 [Homo sapiens]                              34   0.065
gi|42516576 glutaredoxin 5 [Homo sapiens]                              32   0.32 
gi|151301228 formin binding protein 3 [Homo sapiens]                   30   0.72 
gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens]          29   1.6  
gi|239754942 PREDICTED: hypothetical protein [Homo sapiens]            29   2.1  
gi|239749484 PREDICTED: hypothetical protein [Homo sapiens]            29   2.1  
gi|239743622 PREDICTED: hypothetical protein XP_002342908 [Homo ...    29   2.1  
gi|7657345 mitochondrial carrier homolog 1 [Homo sapiens]              29   2.1  
gi|222418604 hypothetical protein LOC257407 [Homo sapiens]             28   3.6  
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]    28   3.6  
gi|226371735 iroquois homeobox 3 [Homo sapiens]                        28   3.6  
gi|50592994 thioredoxin [Homo sapiens]                                 28   3.6  
gi|108860692 prolyl endopeptidase-like isoform D [Homo sapiens]        28   4.6  
gi|156105693 PPAR-alpha interacting complex protein 285 isoform ...    28   4.6  
gi|156105695 PPAR-alpha interacting complex protein 285 isoform ...    28   4.6  
gi|6912372 forkhead box D3 [Homo sapiens]                              27   7.9  
gi|228008410 BEN domain containing 4 isoform b [Homo sapiens]          27   7.9  
gi|148762950 BEN domain containing 4 isoform a [Homo sapiens]          27   7.9  
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    27   7.9  
gi|46275837 CCR4-NOT transcription complex, subunit 1 isoform b ...    27   7.9  
gi|42716275 CCR4-NOT transcription complex, subunit 1 isoform a ...    27   7.9  

>gi|37537704 glutaredoxin 2 isoform 2 [Homo sapiens]
          Length = 164

 Score =  332 bits (851), Expect = 9e-92
 Identities = 164/164 (100%), Positives = 164/164 (100%)

Query: 1   MIWRRAALAGTRLVWSRSGSAGWLDRAAGAAGAAAAAASGMESNTSSSLENLATAPVNQI 60
           MIWRRAALAGTRLVWSRSGSAGWLDRAAGAAGAAAAAASGMESNTSSSLENLATAPVNQI
Sbjct: 1   MIWRRAALAGTRLVWSRSGSAGWLDRAAGAAGAAAAAASGMESNTSSSLENLATAPVNQI 60

Query: 61  QETISDNCVVIFSKTSCSYCTMAKKLFHDMNVNYKVVELDLLEYGNQFQDALYKMTGERT 120
           QETISDNCVVIFSKTSCSYCTMAKKLFHDMNVNYKVVELDLLEYGNQFQDALYKMTGERT
Sbjct: 61  QETISDNCVVIFSKTSCSYCTMAKKLFHDMNVNYKVVELDLLEYGNQFQDALYKMTGERT 120

Query: 121 VPRIFVNGTFIGGATDTHRLHKEGKLLPLVHQCYLKKSKRKEFQ 164
           VPRIFVNGTFIGGATDTHRLHKEGKLLPLVHQCYLKKSKRKEFQ
Sbjct: 121 VPRIFVNGTFIGGATDTHRLHKEGKLLPLVHQCYLKKSKRKEFQ 164


>gi|21361507 glutaredoxin 2 isoform 1 [Homo sapiens]
          Length = 165

 Score =  261 bits (666), Expect = 2e-70
 Identities = 128/137 (93%), Positives = 131/137 (95%)

Query: 28  AGAAGAAAAAASGMESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSCSYCTMAKKLF 87
           +G+ G   +AA  MESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSCSYCTMAKKLF
Sbjct: 29  SGSPGRTRSAARRMESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSCSYCTMAKKLF 88

Query: 88  HDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLL 147
           HDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLL
Sbjct: 89  HDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLL 148

Query: 148 PLVHQCYLKKSKRKEFQ 164
           PLVHQCYLKKSKRKEFQ
Sbjct: 149 PLVHQCYLKKSKRKEFQ 165


>gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens]
          Length = 649

 Score = 65.5 bits (158), Expect = 2e-11
 Identities = 35/91 (38%), Positives = 53/91 (58%)

Query: 60  IQETISDNCVVIFSKTSCSYCTMAKKLFHDMNVNYKVVELDLLEYGNQFQDALYKMTGER 119
           +Q  I  + VVIFS+++C+ CT  KKLF  + V Y V+ELD  E G   +  L ++  E 
Sbjct: 59  LQAYIDGHSVVIFSRSTCTRCTEVKKLFKSLCVPYFVLELDQTEDGRALEGTLSELAAET 118

Query: 120 TVPRIFVNGTFIGGATDTHRLHKEGKLLPLV 150
            +P +FV    IGG   T + ++EG+L  L+
Sbjct: 119 DLPVVFVKQRKIGGHGPTLKAYQEGRLQKLL 149


>gi|169646776 glutaredoxin (thioltransferase) [Homo sapiens]
          Length = 106

 Score = 61.6 bits (148), Expect = 3e-10
 Identities = 30/87 (34%), Positives = 50/87 (57%), Gaps = 3/87 (3%)

Query: 69  VVIFSKTSCSYCTMAKKLFHDMNVNY---KVVELDLLEYGNQFQDALYKMTGERTVPRIF 125
           VV+F K +C YC  A+++   + +     + V++    + N+ QD L ++TG RTVPR+F
Sbjct: 15  VVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDYLQQLTGARTVPRVF 74

Query: 126 VNGTFIGGATDTHRLHKEGKLLPLVHQ 152
           +    IGG +D   L + G+LL  + Q
Sbjct: 75  IGKDCIGGCSDLVSLQQSGELLTRLKQ 101


>gi|4504025 glutaredoxin (thioltransferase) [Homo sapiens]
          Length = 106

 Score = 61.6 bits (148), Expect = 3e-10
 Identities = 30/87 (34%), Positives = 50/87 (57%), Gaps = 3/87 (3%)

Query: 69  VVIFSKTSCSYCTMAKKLFHDMNVNY---KVVELDLLEYGNQFQDALYKMTGERTVPRIF 125
           VV+F K +C YC  A+++   + +     + V++    + N+ QD L ++TG RTVPR+F
Sbjct: 15  VVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDITATNHTNEIQDYLQQLTGARTVPRVF 74

Query: 126 VNGTFIGGATDTHRLHKEGKLLPLVHQ 152
           +    IGG +D   L + G+LL  + Q
Sbjct: 75  IGKDCIGGCSDLVSLQQSGELLTRLKQ 101


>gi|122937349 glutaredoxin, cysteine rich 1 [Homo sapiens]
          Length = 290

 Score = 40.8 bits (94), Expect = 5e-04
 Identities = 24/110 (21%), Positives = 56/110 (50%), Gaps = 7/110 (6%)

Query: 44  NTSSSLENLATAPVNQIQETISDNCVVIFS------KTSCSYCTMAKKLFHDMNVNYKVV 97
           +   +L N  T  + Q    +  + VVI++      +T+   C + +K+F +  V ++  
Sbjct: 114 SAGQALFNNLTKVLQQPSTDLEFDRVVIYTTCLRVVRTTFERCELVRKIFQNHRVKFEEK 173

Query: 98  ELDLL-EYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKL 146
            + L  EYG +  +   +++   ++P +F++G ++GGA     +++ G+L
Sbjct: 174 NIALNGEYGKELDERCRRVSEAPSLPVVFIDGHYLGGAEKILSMNESGEL 223


>gi|95113651 glutaredoxin 3 [Homo sapiens]
          Length = 335

 Score = 33.9 bits (76), Expect = 0.065
 Identities = 18/77 (23%), Positives = 36/77 (46%), Gaps = 3/77 (3%)

Query: 74  KTSCSYCTMAKKLFHDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVPRIFVNGTFIGG 133
           +  C +     ++ +   V Y+    D+LE   + +  L   +   T P+++V G  +GG
Sbjct: 258 EAKCGFSKQILEILNSTGVEYET--FDILE-DEEVRQGLKAYSNWPTYPQLYVKGELVGG 314

Query: 134 ATDTHRLHKEGKLLPLV 150
                 L + G+LLP++
Sbjct: 315 LDIVKELKENGELLPIL 331


>gi|42516576 glutaredoxin 5 [Homo sapiens]
          Length = 157

 Score = 31.6 bits (70), Expect = 0.32
 Identities = 32/149 (21%), Positives = 56/149 (37%), Gaps = 32/149 (21%)

Query: 9   AGTRLVWSR-SGSAGWLDRAAGAAGAAAAAASGMESNTSSSLENLATAPVNQIQETISDN 67
           A   L W R +G  G       AAG+ A      E                Q+   +  +
Sbjct: 9   AAALLRWGRGAGGGGLWGPGVRAAGSGAGGGGSAE----------------QLDALVKKD 52

Query: 68  CVVIFSKTS-----CSYCTMAKKLFHDMNVN----YKVVELDLLEYGNQFQDALYKMTGE 118
            VV+F K +     C +     ++     V     Y V++   L  G      +   +  
Sbjct: 53  KVVVFLKGTPEQPQCGFSNAVVQILRLHGVRDYAAYNVLDDPELRQG------IKDYSNW 106

Query: 119 RTVPRIFVNGTFIGGATDTHRLHKEGKLL 147
            T+P++++NG F+GG     ++H+ G L+
Sbjct: 107 PTIPQVYLNGEFVGGCDILLQMHQNGDLV 135


>gi|151301228 formin binding protein 3 [Homo sapiens]
          Length = 930

 Score = 30.4 bits (67), Expect = 0.72
 Identities = 20/55 (36%), Positives = 29/55 (52%)

Query: 27  AAGAAGAAAAAASGMESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSCSYCT 81
           AA AA AAAAAA+   ++TS+S     T PV    E  S    V+ ++ + +  T
Sbjct: 255 AAAAAAAAAAAAANANASTSASNTVSGTVPVVPEPEVTSIVATVVDNENTVTIST 309


>gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens]
          Length = 551

 Score = 29.3 bits (64), Expect = 1.6
 Identities = 15/48 (31%), Positives = 25/48 (52%)

Query: 103 EYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLLPLV 150
           E G   +  L ++  E  +P +FV    IGG   T + ++EG+L  L+
Sbjct: 4   EDGRALEGTLSELAAETDLPVVFVKQRKIGGHGPTLKAYQEGRLQKLL 51


>gi|239754942 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 145

 Score = 28.9 bits (63), Expect = 2.1
 Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 2/37 (5%)

Query: 15  WSRS--GSAGWLDRAAGAAGAAAAAASGMESNTSSSL 49
           WSR+  G  G     +G  GAAA AAS   +NT  S+
Sbjct: 66  WSRTTLGKRGGNSTGSGGTGAAAGAASSAGTNTYKSM 102


>gi|239749484 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 145

 Score = 28.9 bits (63), Expect = 2.1
 Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 2/37 (5%)

Query: 15  WSRS--GSAGWLDRAAGAAGAAAAAASGMESNTSSSL 49
           WSR+  G  G     +G  GAAA AAS   +NT  S+
Sbjct: 66  WSRTTLGKRGGNSTGSGGTGAAAGAASSAGTNTYKSM 102


>gi|239743622 PREDICTED: hypothetical protein XP_002342908 [Homo
           sapiens]
          Length = 145

 Score = 28.9 bits (63), Expect = 2.1
 Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 2/37 (5%)

Query: 15  WSRS--GSAGWLDRAAGAAGAAAAAASGMESNTSSSL 49
           WSR+  G  G     +G  GAAA AAS   +NT  S+
Sbjct: 66  WSRTTLGKRGGNSTGSGGTGAAAGAASSAGTNTYKSM 102


>gi|7657345 mitochondrial carrier homolog 1 [Homo sapiens]
          Length = 372

 Score = 28.9 bits (63), Expect = 2.1
 Identities = 14/29 (48%), Positives = 19/29 (65%), Gaps = 1/29 (3%)

Query: 15 WSRSGSAGWLDRAAGAAGAAAAAASGMES 43
          W+R G+AG     AG AGA   AA+G+E+
Sbjct: 11 WARGGAAGMAGAGAG-AGARGGAAAGVEA 38


>gi|222418604 hypothetical protein LOC257407 [Homo sapiens]
          Length = 295

 Score = 28.1 bits (61), Expect = 3.6
 Identities = 14/18 (77%), Positives = 15/18 (83%)

Query: 26  RAAGAAGAAAAAASGMES 43
           RAAGAAGAAAAAA  + S
Sbjct: 87  RAAGAAGAAAAAARAIRS 104


>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
          Length = 1759

 Score = 28.1 bits (61), Expect = 3.6
 Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 5/55 (9%)

Query: 1    MIWRRAALAGTRLVWSRSGSAGWLDRAA-----GAAGAAAAAASGMESNTSSSLE 50
            +++ ++A AG  L    +G  G  D AA     GAA AAAAA    + +    LE
Sbjct: 1629 LLFLQSAAAGLGLALGDAGDPGPPDAAAPGPREGAAAAAAAAGESSQEDEEEELE 1683


>gi|226371735 iroquois homeobox 3 [Homo sapiens]
          Length = 501

 Score = 28.1 bits (61), Expect = 3.6
 Identities = 17/39 (43%), Positives = 22/39 (56%), Gaps = 2/39 (5%)

Query: 17 RSGSAGWLDRAAGAAGAAAAAASGMESNTSSSLENLATA 55
          R G+AG    +AGA G   A AS  E N S SL N+ ++
Sbjct: 19 RPGAAGGSGGSAGARGGLGAGAS--ELNASGSLSNVLSS 55


>gi|50592994 thioredoxin [Homo sapiens]
          Length = 105

 Score = 28.1 bits (61), Expect = 3.6
 Identities = 13/29 (44%), Positives = 15/29 (51%)

Query: 69 VVIFSKTSCSYCTMAKKLFHDMNVNYKVV 97
          VV FS T C  C M K  FH ++  Y  V
Sbjct: 24 VVDFSATWCGPCKMIKPFFHSLSEKYSNV 52


>gi|108860692 prolyl endopeptidase-like isoform D [Homo sapiens]
          Length = 661

 Score = 27.7 bits (60), Expect = 4.6
 Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 10/64 (15%)

Query: 86  LFHDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGK 145
           LF  M  N KV++LD+      F+D          +  ++VN   IG A D+ R  K+GK
Sbjct: 339 LFFTMKRNTKVIDLDM------FKDHCVLFLKHSNL--LYVN--VIGLADDSVRSLKDGK 388

Query: 146 LLPL 149
           L+P+
Sbjct: 389 LVPM 392


>gi|156105693 PPAR-alpha interacting complex protein 285 isoform 1
            [Homo sapiens]
          Length = 2649

 Score = 27.7 bits (60), Expect = 4.6
 Identities = 17/45 (37%), Positives = 22/45 (48%)

Query: 6    AALAGTRLVWSRSGSAGWLDRAAGAAGAAAAAASGMESNTSSSLE 50
            A  A T    + +G A   D   GA  A AAAA+G+ES  +   E
Sbjct: 1014 ATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEAEDAE 1058


>gi|156105695 PPAR-alpha interacting complex protein 285 isoform 2
           [Homo sapiens]
          Length = 2080

 Score = 27.7 bits (60), Expect = 4.6
 Identities = 17/45 (37%), Positives = 22/45 (48%)

Query: 6   AALAGTRLVWSRSGSAGWLDRAAGAAGAAAAAASGMESNTSSSLE 50
           A  A T    + +G A   D   GA  A AAAA+G+ES  +   E
Sbjct: 445 ATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEAEDAE 489


>gi|6912372 forkhead box D3 [Homo sapiens]
          Length = 478

 Score = 26.9 bits (58), Expect = 7.9
 Identities = 21/56 (37%), Positives = 31/56 (55%), Gaps = 7/56 (12%)

Query: 4   RRAALAGTRL---VWSRSGSAGWLDRAAGAAGAAAAAASGMESNTSS----SLENL 52
           R+AA  G++L   +  +  S G    AAG AGAA   AS ++S  S+    S+EN+
Sbjct: 328 RKAAAFGSQLGPGLQLQLNSLGAAAAAAGTAGAAGTTASLIKSEPSARPSFSIENI 383


>gi|228008410 BEN domain containing 4 isoform b [Homo sapiens]
          Length = 441

 Score = 26.9 bits (58), Expect = 7.9
 Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 2/46 (4%)

Query: 32  GAAAAAASGMESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSC 77
           GAAAAA +G   + S+SLE   +A    I +  +  C  + S  +C
Sbjct: 141 GAAAAAGTGGTGSDSASLE--LSAESRMILDAFAQQCSRVLSLLNC 184


>gi|148762950 BEN domain containing 4 isoform a [Homo sapiens]
          Length = 534

 Score = 26.9 bits (58), Expect = 7.9
 Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 2/46 (4%)

Query: 32  GAAAAAASGMESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSC 77
           GAAAAA +G   + S+SLE   +A    I +  +  C  + S  +C
Sbjct: 141 GAAAAAGTGGTGSDSASLE--LSAESRMILDAFAQQCSRVLSLLNC 184


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 26.9 bits (58), Expect = 7.9
 Identities = 16/57 (28%), Positives = 26/57 (45%), Gaps = 2/57 (3%)

Query: 6    AALAGTRLVWSRSGSAGWLDRAAGAAGAAAAAASGMESN--TSSSLENLATAPVNQI 60
            ++ AG  L W+R GS G  D   G A       S ++    +  S  +L + PV+ +
Sbjct: 1884 SSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSL 1940


>gi|46275837 CCR4-NOT transcription complex, subunit 1 isoform b [Homo
            sapiens]
          Length = 1551

 Score = 26.9 bits (58), Expect = 7.9
 Identities = 15/44 (34%), Positives = 20/44 (45%), Gaps = 2/44 (4%)

Query: 79   YCTMAKKLFHDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVP 122
            YC     + H M   + + E   +EYG Q +D   KM G  T P
Sbjct: 971  YCQHLASISHFMQFPHHLQEY--IEYGQQSRDPPVKMQGSITTP 1012


>gi|42716275 CCR4-NOT transcription complex, subunit 1 isoform a [Homo
            sapiens]
          Length = 2376

 Score = 26.9 bits (58), Expect = 7.9
 Identities = 15/44 (34%), Positives = 20/44 (45%), Gaps = 2/44 (4%)

Query: 79   YCTMAKKLFHDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVP 122
            YC     + H M   + + E   +EYG Q +D   KM G  T P
Sbjct: 971  YCQHLASISHFMQFPHHLQEY--IEYGQQSRDPPVKMQGSITTP 1012


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.130    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,578,765
Number of Sequences: 37866
Number of extensions: 206307
Number of successful extensions: 1371
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1342
Number of HSP's gapped (non-prelim): 35
length of query: 164
length of database: 18,247,518
effective HSP length: 94
effective length of query: 70
effective length of database: 14,688,114
effective search space: 1028167980
effective search space used: 1028167980
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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