Guide to the Human Genome
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Search of human proteins with 34878735

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|34878735 F-box protein 44 isoform 1 [Homo sapiens]
         (255 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|34878735 F-box protein 44 isoform 1 [Homo sapiens]                 552   e-157
gi|62388868 F-box protein 44 isoform 1 [Homo sapiens]                 552   e-157
gi|8922188 F-box only protein 6 [Homo sapiens]                        405   e-113
gi|34878749 F-box protein 44 isoform 2 [Homo sapiens]                 264   5e-71
gi|34878753 F-box protein 44 isoform 2 [Homo sapiens]                 264   5e-71
gi|15812198 F-box only protein 2 [Homo sapiens]                       256   1e-68
gi|30520327 F-box protein 27 [Homo sapiens]                           177   1e-44
gi|22325388 F-box protein FBG4 isoform 1 [Homo sapiens]               163   2e-40
gi|18643385 F-box protein FBG4 isoform 2 [Homo sapiens]               163   2e-40
gi|47825361 non-specific cytotoxic cell receptor protein 1 homol...    85   5e-17
gi|30795117 F-box only protein, helicase, 18 isoform 1 [Homo sap...    39   0.003
gi|30795119 F-box only protein, helicase, 18 isoform 2 [Homo sap...    39   0.003
gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens]     39   0.006
gi|83035136 F-box protein 31 [Homo sapiens]                            37   0.022
gi|27312027 F-box only protein 16 [Homo sapiens]                       36   0.029
gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [H...    34   0.11 
gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [H...    34   0.11 
gi|118402584 F-box and WD repeat domain containing 2 [Homo sapiens]    34   0.14 
gi|124248558 F-box and WD-40 domain protein 9 [Homo sapiens]           32   0.54 
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H...    31   0.92 
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H...    31   0.92 
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H...    31   0.92 
gi|236463969 neuregulin 1 isoform HRG-beta3b [Homo sapiens]            31   1.2  
gi|236462773 neuregulin 1 isoform HRG-beta1d [Homo sapiens]            31   1.2  
gi|236462348 neuregulin 1 isoform HRG-beta1b [Homo sapiens]            31   1.2  
gi|236461509 neuregulin 1 isoform HRG-beta1c [Homo sapiens]            31   1.2  
gi|116006959 neuregulin 1 isoform HRG-beta3 [Homo sapiens]             31   1.2  
gi|116006955 neuregulin 1 isoform HRG-beta1 [Homo sapiens]             31   1.2  
gi|7669518 neuregulin 1 isoform SMDF [Homo sapiens]                    31   1.2  
gi|116006967 neuregulin 1 isoform GGF2 [Homo sapiens]                  31   1.2  

>gi|34878735 F-box protein 44 isoform 1 [Homo sapiens]
          Length = 255

 Score =  552 bits (1422), Expect = e-157
 Identities = 255/255 (100%), Positives = 255/255 (100%)

Query: 1   MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 60
           MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED
Sbjct: 1   MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 60

Query: 61  WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120
           WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND
Sbjct: 61  WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120

Query: 121 QVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQL 180
           QVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQL
Sbjct: 121 QVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQL 180

Query: 181 LSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYG 240
           LSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYG
Sbjct: 181 LSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYG 240

Query: 241 PRVTNSSITIGPPLP 255
           PRVTNSSITIGPPLP
Sbjct: 241 PRVTNSSITIGPPLP 255


>gi|62388868 F-box protein 44 isoform 1 [Homo sapiens]
          Length = 255

 Score =  552 bits (1422), Expect = e-157
 Identities = 255/255 (100%), Positives = 255/255 (100%)

Query: 1   MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 60
           MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED
Sbjct: 1   MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 60

Query: 61  WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120
           WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND
Sbjct: 61  WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120

Query: 121 QVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQL 180
           QVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQL
Sbjct: 121 QVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQL 180

Query: 181 LSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYG 240
           LSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYG
Sbjct: 181 LSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYG 240

Query: 241 PRVTNSSITIGPPLP 255
           PRVTNSSITIGPPLP
Sbjct: 241 PRVTNSSITIGPPLP 255


>gi|8922188 F-box only protein 6 [Homo sapiens]
          Length = 293

 Score =  405 bits (1042), Expect = e-113
 Identities = 190/253 (75%), Positives = 210/253 (83%)

Query: 2   AVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITEDW 61
           A+ +INELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDL+TLWKRKCLREGFIT+DW
Sbjct: 9   ALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLREGFITKDW 68

Query: 62  DQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPNDQ 121
           DQPVADWKIFYFLRSLHRNLL NPCAEE    W +D NGGD WKVE L      +FP+ +
Sbjct: 69  DQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAHGTDFPDPK 128

Query: 122 VKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQLL 181
           VKKYFVTSY  CLKSQ+VDL AEGYWEEL+DT RPDI VKDWFAAR DCG  YQL VQL 
Sbjct: 129 VKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAARADCGCTYQLKVQLA 188

Query: 182 SSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYGP 241
           S+ +  L +F+P P TIQQ ++A W EVS+TFS+YP GVRYI FQHGG DT YWAGWYGP
Sbjct: 189 SADYFVLASFEPPPVTIQQWNNATWTEVSYTFSDYPRGVRYILFQHGGRDTQYWAGWYGP 248

Query: 242 RVTNSSITIGPPL 254
           RVTNSSI + P +
Sbjct: 249 RVTNSSIVVSPKM 261


>gi|34878749 F-box protein 44 isoform 2 [Homo sapiens]
          Length = 224

 Score =  264 bits (675), Expect = 5e-71
 Identities = 122/123 (99%), Positives = 123/123 (100%)

Query: 1   MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 60
           MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED
Sbjct: 1   MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 60

Query: 61  WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120
           WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND
Sbjct: 61  WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120

Query: 121 QVK 123
           QV+
Sbjct: 121 QVR 123


>gi|34878753 F-box protein 44 isoform 2 [Homo sapiens]
          Length = 224

 Score =  264 bits (675), Expect = 5e-71
 Identities = 122/123 (99%), Positives = 123/123 (100%)

Query: 1   MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 60
           MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED
Sbjct: 1   MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 60

Query: 61  WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120
           WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND
Sbjct: 61  WDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120

Query: 121 QVK 123
           QV+
Sbjct: 121 QVR 123


>gi|15812198 F-box only protein 2 [Homo sapiens]
          Length = 296

 Score =  256 bits (654), Expect = 1e-68
 Identities = 124/254 (48%), Positives = 165/254 (64%), Gaps = 3/254 (1%)

Query: 2   AVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITEDW 61
           A   ++ELPE +LL +   +PA +L+  CRLVC  W++L+D   LW  KC +EG + E  
Sbjct: 43  AAAYLDELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEGG 102

Query: 62  DQPVAD-WKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPND 120
            +   D W+ FYFL    RNLL NPC EE  E W    +GGD W+VE+L  D   EF +D
Sbjct: 103 VEEERDHWQQFYFLSKRRRNLLRNPCGEEDLEGWCDVEHGGDGWRVEELPGDSGVEFTHD 162

Query: 121 Q-VKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQ 179
           + VKKYF +S+  C K+QV+DL+AEGYWEEL+DTT+P I VKDW++ R D G  Y+L V+
Sbjct: 163 ESVKKYFASSFEWCRKAQVIDLQAEGYWEELLDTTQPAIVVKDWYSGRSDAGCLYELTVK 222

Query: 180 LLSSAHAPLGTFQPDPATIQQKSD-AKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGW 238
           LLS     L  F      + Q SD   W E+SHTF++Y PGVR++ F+HGG D+ YW GW
Sbjct: 223 LLSEHENVLAEFSSGQVAVPQDSDGGGWMEISHTFTDYGPGVRFVRFEHGGQDSVYWKGW 282

Query: 239 YGPRVTNSSITIGP 252
           +G RVTNSS+ + P
Sbjct: 283 FGARVTNSSVWVEP 296


>gi|30520327 F-box protein 27 [Homo sapiens]
          Length = 283

 Score =  177 bits (448), Expect = 1e-44
 Identities = 102/259 (39%), Positives = 138/259 (53%), Gaps = 18/259 (6%)

Query: 5   NINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFIT------ 58
           ++++LP  +LL + +HVP R LL  CR VC  WR L+D   LW     R+   T      
Sbjct: 25  DLSQLPPELLLVVLSHVPPRTLLGRCRQVCRGWRALVDGQALWLLILARDHGATGRALLH 84

Query: 59  --EDWDQPVADWKI-----FYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSR 111
                  P  + +      F   R + RNL+ NPC +EG   W +  +GGD W VE+   
Sbjct: 85  LARSCQSPARNARPCPLGRFCARRPIGRNLIRNPCGQEGLRKWMVQ-HGGDGWVVEE--- 140

Query: 112 DQRKEFPNDQVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCG 171
             R   P    +  FVTS+  C K QV+DL+ EG W EL+D+ R +I V DW+ AR D G
Sbjct: 141 -NRTTVPGAPSQTCFVTSFSWCCKKQVLDLEEEGLWPELLDSGRIEICVSDWWGARHDSG 199

Query: 172 SKYQLCVQLLSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVD 231
             Y+L VQLL +    L  F   P  I Q ++     V+H FSN   GVR++ F+H G D
Sbjct: 200 CMYRLLVQLLDANQTVLDKFSAVPDPIPQWNNNACLHVTHVFSNIKMGVRFVSFEHRGQD 259

Query: 232 THYWAGWYGPRVTNSSITI 250
           T +WAG YG RVTNSS+ +
Sbjct: 260 TQFWAGHYGARVTNSSVIV 278


>gi|22325388 F-box protein FBG4 isoform 1 [Homo sapiens]
          Length = 287

 Score =  163 bits (412), Expect = 2e-40
 Identities = 89/263 (33%), Positives = 137/263 (52%), Gaps = 25/263 (9%)

Query: 6   INELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLW------------------ 47
           ++ LP  +L+++ +HVP R L+  CR VC  WRD++D  T+W                  
Sbjct: 27  LDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWLLQLARDRSAEGRALYAV 86

Query: 48  KRKCLREGFITEDWDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVE 107
            ++CL      E++  P+     +       RNL+ N C E+GF  W ++ +GG+ W +E
Sbjct: 87  AQRCLPSNEDKEEF--PLCALARYCLRAPFGRNLIFNSCGEQGFRGWEVE-HGGNGWAIE 143

Query: 108 DLSRDQRKEFPNDQVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAAR 167
                     P    +  FVTS+  C K Q+VDL  EG W+EL+D+ + +I V DW+ AR
Sbjct: 144 K----NLTPVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQELLDSAQIEICVADWWGAR 199

Query: 168 PDCGSKYQLCVQLLSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQH 227
            +CG  YQL V+LL      +  F   P  + Q ++   R+VSH F+N+  G+RY+ F+ 
Sbjct: 200 ENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTERGCRQVSHVFTNFGKGIRYVSFEQ 259

Query: 228 GGVDTHYWAGWYGPRVTNSSITI 250
            G D   W G YG  VT+SS+ +
Sbjct: 260 YGRDVSSWVGHYGALVTHSSVRV 282


>gi|18643385 F-box protein FBG4 isoform 2 [Homo sapiens]
          Length = 278

 Score =  163 bits (412), Expect = 2e-40
 Identities = 89/263 (33%), Positives = 137/263 (52%), Gaps = 25/263 (9%)

Query: 6   INELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLW------------------ 47
           ++ LP  +L+++ +HVP R L+  CR VC  WRD++D  T+W                  
Sbjct: 18  LDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWLLQLARDRSAEGRALYAV 77

Query: 48  KRKCLREGFITEDWDQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVE 107
            ++CL      E++  P+     +       RNL+ N C E+GF  W ++ +GG+ W +E
Sbjct: 78  AQRCLPSNEDKEEF--PLCALARYCLRAPFGRNLIFNSCGEQGFRGWEVE-HGGNGWAIE 134

Query: 108 DLSRDQRKEFPNDQVKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAAR 167
                     P    +  FVTS+  C K Q+VDL  EG W+EL+D+ + +I V DW+ AR
Sbjct: 135 K----NLTPVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQELLDSAQIEICVADWWGAR 190

Query: 168 PDCGSKYQLCVQLLSSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQH 227
            +CG  YQL V+LL      +  F   P  + Q ++   R+VSH F+N+  G+RY+ F+ 
Sbjct: 191 ENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTERGCRQVSHVFTNFGKGIRYVSFEQ 250

Query: 228 GGVDTHYWAGWYGPRVTNSSITI 250
            G D   W G YG  VT+SS+ +
Sbjct: 251 YGRDVSSWVGHYGALVTHSSVRV 273


>gi|47825361 non-specific cytotoxic cell receptor protein 1 homolog
           [Homo sapiens]
          Length = 275

 Score = 85.1 bits (209), Expect = 5e-17
 Identities = 58/184 (31%), Positives = 88/184 (47%), Gaps = 5/184 (2%)

Query: 68  WKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPNDQVKKYFV 127
           WK+    R L+RNLL +P  E    +      G  +  +E L   +      +++++   
Sbjct: 92  WKLLLLRRPLYRNLLRSPNPEGINIYEPAPPTGPTQRPLETLGNFRGWYIRTEKLQQ--- 148

Query: 128 TSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQLLSS-AHA 186
            +    +K Q VDL AEG WEEL+D  +P I V DWF         Y+L V LL++    
Sbjct: 149 -NQSWTVKQQCVDLLAEGLWEELLDDEQPAITVMDWFEDSRLDACVYELHVWLLAADRRT 207

Query: 187 PLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYGPRVTNS 246
            +      P T  +    +W +VSH F +Y PGVR+I F H   +     G    RVT+S
Sbjct: 208 VIAQHHVAPRTSGRGPPGRWVQVSHVFRHYGPGVRFIHFLHKAKNRMEPGGLRRTRVTDS 267

Query: 247 SITI 250
           S+++
Sbjct: 268 SVSV 271


>gi|30795117 F-box only protein, helicase, 18 isoform 1 [Homo
           sapiens]
          Length = 1094

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 2/50 (4%)

Query: 2   AVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLID--LVTLWKR 49
           A+ +I  LP  +L  +F  +P   L  N  LVC LWR++I   L   WK+
Sbjct: 259 ALSHICSLPSEVLRHVFAFLPVEDLYWNLSLVCHLWREIISDPLFIPWKK 308


>gi|30795119 F-box only protein, helicase, 18 isoform 2 [Homo
           sapiens]
          Length = 1043

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 2/50 (4%)

Query: 2   AVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLID--LVTLWKR 49
           A+ +I  LP  +L  +F  +P   L  N  LVC LWR++I   L   WK+
Sbjct: 208 ALSHICSLPSEVLRHVFAFLPVEDLYWNLSLVCHLWREIISDPLFIPWKK 257


>gi|8923179 F-box and leucine-rich repeat protein 12 [Homo
          sapiens]
          Length = 326

 Score = 38.5 bits (88), Expect = 0.006
 Identities = 17/41 (41%), Positives = 28/41 (68%), Gaps = 1/41 (2%)

Query: 8  ELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWK 48
          ELP+++LLE+F+++P R  +   R VC  W+ L+D   LW+
Sbjct: 6  ELPDSVLLEIFSYLPVRDRIRISR-VCHRWKRLVDDRWLWR 45


>gi|83035136 F-box protein 31 [Homo sapiens]
          Length = 539

 Score = 36.6 bits (83), Expect = 0.022
 Identities = 17/53 (32%), Positives = 31/53 (58%), Gaps = 1/53 (1%)

Query: 8   ELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITED 60
           ELP  +L+E+F  +P   L  +   VC+ +R ++   T+W+R+C  E  + E+
Sbjct: 69  ELPPELLVEIFASLPGTDLP-SLAQVCTKFRRILHTDTIWRRRCREEYGVCEN 120


>gi|27312027 F-box only protein 16 [Homo sapiens]
          Length = 292

 Score = 36.2 bits (82), Expect = 0.029
 Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 5/75 (6%)

Query: 8   ELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITEDWDQPVAD 67
           +LP  + L +F+ +  R L   C  VC  W++L +L  LW  KCLR  +       P   
Sbjct: 91  KLPRVLSLYIFSFLDPRSLC-RCAQVCWHWKNLAELDQLWMLKCLRFNWYINFSPTPFEQ 149

Query: 68  --WKIFY--FLRSLH 78
             WK  Y   ++ LH
Sbjct: 150 GIWKKHYIQMVKELH 164


>gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [Homo
           sapiens]
          Length = 532

 Score = 34.3 bits (77), Expect = 0.11
 Identities = 15/65 (23%), Positives = 32/65 (49%), Gaps = 1/65 (1%)

Query: 8   ELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITEDWDQPVAD 67
           +LP  + + +F ++  ++L   C  V   W+ + +   LW R C +EG + +      + 
Sbjct: 52  QLPYELAINIFQYLDRKELG-RCAQVSKTWKVIAEDEVLWYRLCQQEGHLPDSSISDYSC 110

Query: 68  WKIFY 72
           WK+ +
Sbjct: 111 WKLIF 115


>gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [Homo
           sapiens]
          Length = 598

 Score = 34.3 bits (77), Expect = 0.11
 Identities = 15/65 (23%), Positives = 32/65 (49%), Gaps = 1/65 (1%)

Query: 8   ELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITEDWDQPVAD 67
           +LP  + + +F ++  ++L   C  V   W+ + +   LW R C +EG + +      + 
Sbjct: 118 QLPYELAINIFQYLDRKELG-RCAQVSKTWKVIAEDEVLWYRLCQQEGHLPDSSISDYSC 176

Query: 68  WKIFY 72
           WK+ +
Sbjct: 177 WKLIF 181


>gi|118402584 F-box and WD repeat domain containing 2 [Homo sapiens]
          Length = 454

 Score = 33.9 bits (76), Expect = 0.14
 Identities = 24/73 (32%), Positives = 30/73 (41%), Gaps = 4/73 (5%)

Query: 25  QLLLNCRLVCSLWRDLIDLVT-LWKRKCLREGFITEDWDQPVADWKIFYFLRSLHRNLLH 83
           Q LL C LV   W  +I   T +W+  C   G+  +D  Q    WK  Y    L    L 
Sbjct: 75  QTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDALHWKKVYLKAILRMKQLE 134

Query: 84  NPCAEEGFEFWSL 96
           +    E FE  SL
Sbjct: 135 D---HEAFETSSL 144


>gi|124248558 F-box and WD-40 domain protein 9 [Homo sapiens]
          Length = 458

 Score = 32.0 bits (71), Expect = 0.54
 Identities = 16/45 (35%), Positives = 25/45 (55%)

Query: 9   LPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLR 53
           LP  +LLE+ +++ AR +L     VC   RDL+     W+ + LR
Sbjct: 82  LPPELLLEICSYLDARLVLHVLSRVCHALRDLVSDHVTWRLRALR 126


>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
           sapiens]
          Length = 589

 Score = 31.2 bits (69), Expect = 0.92
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 1/50 (2%)

Query: 6   INELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREG 55
           I+ LP+ + L + + +  + LL   +  C  WR L +   LW+ KC  EG
Sbjct: 163 ISLLPKELALYVLSFLEPKDLLQAAQ-TCRYWRILAEDNLLWREKCKEEG 211


>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
           sapiens]
          Length = 707

 Score = 31.2 bits (69), Expect = 0.92
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 1/50 (2%)

Query: 6   INELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREG 55
           I+ LP+ + L + + +  + LL   +  C  WR L +   LW+ KC  EG
Sbjct: 281 ISLLPKELALYVLSFLEPKDLLQAAQ-TCRYWRILAEDNLLWREKCKEEG 329


>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
           sapiens]
          Length = 627

 Score = 31.2 bits (69), Expect = 0.92
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 1/50 (2%)

Query: 6   INELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREG 55
           I+ LP+ + L + + +  + LL   +  C  WR L +   LW+ KC  EG
Sbjct: 201 ISLLPKELALYVLSFLEPKDLLQAAQ-TCRYWRILAEDNLLWREKCKEEG 249


>gi|236463969 neuregulin 1 isoform HRG-beta3b [Homo sapiens]
          Length = 207

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 9/53 (16%)

Query: 86  CAEEGFEFWSLDVNGGDEWKVEDLSRDQR------KEFPNDQVKKYFVTSYYT 132
           CAE+   F    VNGG+ + V+DLS   R       EF  D+ + Y + S+Y+
Sbjct: 148 CAEKEKTFC---VNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYS 197


>gi|236462773 neuregulin 1 isoform HRG-beta1d [Homo sapiens]
          Length = 590

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 10/75 (13%)

Query: 86  CAEEGFEFWSLDVNGGDEWKVEDLSRDQR------KEFPNDQVKKYFVTSYYTCLKSQVV 139
           CAE+   F    VNGG+ + V+DLS   R       EF  D+ + Y + S+Y  L  + +
Sbjct: 127 CAEKEKTFC---VNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFM 183

Query: 140 DLKAEGYWEELMDTT 154
           + + E Y + ++  T
Sbjct: 184 EAE-ELYQKRVLTIT 197


>gi|236462348 neuregulin 1 isoform HRG-beta1b [Homo sapiens]
          Length = 624

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 10/75 (13%)

Query: 86  CAEEGFEFWSLDVNGGDEWKVEDLSRDQR------KEFPNDQVKKYFVTSYYTCLKSQVV 139
           CAE+   F    VNGG+ + V+DLS   R       EF  D+ + Y + S+Y  L  + +
Sbjct: 161 CAEKEKTFC---VNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFM 217

Query: 140 DLKAEGYWEELMDTT 154
           + + E Y + ++  T
Sbjct: 218 EAE-ELYQKRVLTIT 231


>gi|236461509 neuregulin 1 isoform HRG-beta1c [Homo sapiens]
          Length = 607

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 10/75 (13%)

Query: 86  CAEEGFEFWSLDVNGGDEWKVEDLSRDQR------KEFPNDQVKKYFVTSYYTCLKSQVV 139
           CAE+   F    VNGG+ + V+DLS   R       EF  D+ + Y + S+Y  L  + +
Sbjct: 144 CAEKEKTFC---VNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFM 200

Query: 140 DLKAEGYWEELMDTT 154
           + + E Y + ++  T
Sbjct: 201 EAE-ELYQKRVLTIT 214


>gi|116006959 neuregulin 1 isoform HRG-beta3 [Homo sapiens]
          Length = 241

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 9/53 (16%)

Query: 86  CAEEGFEFWSLDVNGGDEWKVEDLSRDQR------KEFPNDQVKKYFVTSYYT 132
           CAE+   F    VNGG+ + V+DLS   R       EF  D+ + Y + S+Y+
Sbjct: 182 CAEKEKTFC---VNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYS 231


>gi|116006955 neuregulin 1 isoform HRG-beta1 [Homo sapiens]
          Length = 645

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 10/75 (13%)

Query: 86  CAEEGFEFWSLDVNGGDEWKVEDLSRDQR------KEFPNDQVKKYFVTSYYTCLKSQVV 139
           CAE+   F    VNGG+ + V+DLS   R       EF  D+ + Y + S+Y  L  + +
Sbjct: 182 CAEKEKTFC---VNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYKHLGIEFM 238

Query: 140 DLKAEGYWEELMDTT 154
           + + E Y + ++  T
Sbjct: 239 EAE-ELYQKRVLTIT 252


>gi|7669518 neuregulin 1 isoform SMDF [Homo sapiens]
          Length = 296

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 9/53 (16%)

Query: 86  CAEEGFEFWSLDVNGGDEWKVEDLSRDQR------KEFPNDQVKKYFVTSYYT 132
           CAE+   F    VNGG+ + V+DLS   R       EF  D+ + Y + S+Y+
Sbjct: 237 CAEKEKTFC---VNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYS 286


>gi|116006967 neuregulin 1 isoform GGF2 [Homo sapiens]
          Length = 422

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 19/53 (35%), Positives = 28/53 (52%), Gaps = 9/53 (16%)

Query: 86  CAEEGFEFWSLDVNGGDEWKVEDLSRDQR------KEFPNDQVKKYFVTSYYT 132
           CAE+   F    VNGG+ + V+DLS   R       EF  D+ + Y + S+Y+
Sbjct: 363 CAEKEKTFC---VNGGECFMVKDLSNPSRYLCKCPNEFTGDRCQNYVMASFYS 412


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.470 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,568,004
Number of Sequences: 37866
Number of extensions: 531968
Number of successful extensions: 1023
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 986
Number of HSP's gapped (non-prelim): 44
length of query: 255
length of database: 18,247,518
effective HSP length: 100
effective length of query: 155
effective length of database: 14,460,918
effective search space: 2241442290
effective search space used: 2241442290
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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