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Search of human proteins with 34447229
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|34447229 syntaxin 16 isoform b [Homo sapiens]
(304 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|34447229 syntaxin 16 isoform b [Homo sapiens] 590 e-169
gi|198041692 syntaxin 16 isoform d [Homo sapiens] 585 e-167
gi|198041688 syntaxin 16 isoform c [Homo sapiens] 580 e-166
gi|47778943 syntaxin 16 isoform a [Homo sapiens] 578 e-165
gi|170932494 syntaxin 7 [Homo sapiens] 93 3e-19
gi|28933465 syntaxin 12 [Homo sapiens] 93 3e-19
gi|4759182 syntaxin 1A (brain) [Homo sapiens] 85 7e-17
gi|4759184 syntaxin 3 [Homo sapiens] 82 4e-16
gi|16418379 syntaxin 1B [Homo sapiens] 81 1e-15
gi|37577287 syntaxin 2 isoform 1 [Homo sapiens] 71 1e-12
gi|37577162 syntaxin 2 isoform 2 [Homo sapiens] 69 4e-12
gi|20149560 syntaxin 4 [Homo sapiens] 69 5e-12
gi|94400932 syntaxin 5 [Homo sapiens] 60 2e-09
gi|223972648 t-SNARE domain containing 1 [Homo sapiens] 52 5e-07
gi|33667038 syntaxin 11 [Homo sapiens] 48 9e-06
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 44 1e-04
gi|49258196 syntaxin 19 [Homo sapiens] 41 0.002
gi|4507285 syntaxin 10 [Homo sapiens] 38 0.010
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 38 0.013
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 38 0.013
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 38 0.013
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 38 0.013
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 38 0.013
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 38 0.013
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 38 0.013
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 38 0.013
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 38 0.013
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 38 0.013
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 37 0.028
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 37 0.028
>gi|34447229 syntaxin 16 isoform b [Homo sapiens]
Length = 304
Score = 590 bits (1522), Expect = e-169
Identities = 304/304 (100%), Positives = 304/304 (100%)
Query: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQLADDRMALVSGISLDPEAAIGVTKRPPPKWVDG 60
MATRRLTDAFLLLRNNSIQNRQLLAEQLADDRMALVSGISLDPEAAIGVTKRPPPKWVDG
Sbjct: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQLADDRMALVSGISLDPEAAIGVTKRPPPKWVDG 60
Query: 61 VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 120
VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ
Sbjct: 61 VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 120
Query: 121 ALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTS 180
ALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTS
Sbjct: 121 ALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTS 180
Query: 181 VPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMI 240
VPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMI
Sbjct: 181 VPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMI 240
Query: 241 VEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLVG 300
VEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLVG
Sbjct: 241 VEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLVG 300
Query: 301 VKSR 304
VKSR
Sbjct: 301 VKSR 304
>gi|198041692 syntaxin 16 isoform d [Homo sapiens]
Length = 308
Score = 585 bits (1507), Expect = e-167
Identities = 304/308 (98%), Positives = 304/308 (98%), Gaps = 4/308 (1%)
Query: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQ----LADDRMALVSGISLDPEAAIGVTKRPPPK 56
MATRRLTDAFLLLRNNSIQNRQLLAEQ LADDRMALVSGISLDPEAAIGVTKRPPPK
Sbjct: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQELDELADDRMALVSGISLDPEAAIGVTKRPPPK 60
Query: 57 WVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQ 116
WVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQ
Sbjct: 61 WVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQ 120
Query: 117 RAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHF 176
RAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHF
Sbjct: 121 RAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHF 180
Query: 177 FDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDL 236
FDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDL
Sbjct: 181 FDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDL 240
Query: 237 GAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIV 296
GAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIV
Sbjct: 241 GAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIV 300
Query: 297 VLVGVKSR 304
VLVGVKSR
Sbjct: 301 VLVGVKSR 308
>gi|198041688 syntaxin 16 isoform c [Homo sapiens]
Length = 321
Score = 580 bits (1494), Expect = e-166
Identities = 304/321 (94%), Positives = 304/321 (94%), Gaps = 17/321 (5%)
Query: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQ-----------------LADDRMALVSGISLDP 43
MATRRLTDAFLLLRNNSIQNRQLLAEQ LADDRMALVSGISLDP
Sbjct: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAALADDRMALVSGISLDP 60
Query: 44 EAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEI 103
EAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEI
Sbjct: 61 EAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEI 120
Query: 104 TTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYL 163
TTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYL
Sbjct: 121 TTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYL 180
Query: 164 KRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIV 223
KRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIV
Sbjct: 181 KRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIV 240
Query: 224 QSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLV 283
QSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLV
Sbjct: 241 QSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLV 300
Query: 284 ILILFVIIIVLIVVLVGVKSR 304
ILILFVIIIVLIVVLVGVKSR
Sbjct: 301 ILILFVIIIVLIVVLVGVKSR 321
>gi|47778943 syntaxin 16 isoform a [Homo sapiens]
Length = 325
Score = 578 bits (1490), Expect = e-165
Identities = 304/325 (93%), Positives = 304/325 (93%), Gaps = 21/325 (6%)
Query: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQ---------------------LADDRMALVSGI 39
MATRRLTDAFLLLRNNSIQNRQLLAEQ LADDRMALVSGI
Sbjct: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGI 60
Query: 40 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH 99
SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH
Sbjct: 61 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH 120
Query: 100 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ 159
AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ
Sbjct: 121 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ 180
Query: 160 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI 219
SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI
Sbjct: 181 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI 240
Query: 220 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR 279
RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR
Sbjct: 241 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR 300
Query: 280 KMLVILILFVIIIVLIVVLVGVKSR 304
KMLVILILFVIIIVLIVVLVGVKSR
Sbjct: 301 KMLVILILFVIIIVLIVVLVGVKSR 325
>gi|170932494 syntaxin 7 [Homo sapiens]
Length = 261
Score = 93.2 bits (230), Expect = 3e-19
Identities = 73/237 (30%), Positives = 115/237 (48%), Gaps = 14/237 (5%)
Query: 73 QKMKELASLHDKHLNR-PTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSE 131
QK+ + + + LN+ T DS E ++ Q QL + ++ S SE
Sbjct: 23 QKITQCSVEIQRTLNQLGTPQDSPELRQQLQQKQQYTNQLAKETDKYIKEFGSLPTTPSE 82
Query: 132 QEGRLL--GNVVASLAQALQELSTSFRHAQSGYLKRMKN--REERSQHFFDTSVPLMDDG 187
Q R + +VA +L T+F+ Q +R K R+ S P
Sbjct: 83 QRQRKIQKDRLVAEFTTSL----TNFQKVQRQAAEREKEFVARVRASSRVSGSFPEDSSK 138
Query: 188 DDNTLYHRGFTEDQLV-----LVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVE 242
+ N + T+ Q+ + E + ++ ERE IRQ+ I D+NEIF+DLG MI E
Sbjct: 139 ERNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHE 198
Query: 243 QGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLV 299
QG V+D I+ NVE + + + +QL +A YQ+K+RK L I+IL ++I V I+ L+
Sbjct: 199 QGDVIDSIEANVENAEVHVQQANQQLSRAADYQRKSRKTLCIIILILVIGVAIISLI 255
>gi|28933465 syntaxin 12 [Homo sapiens]
Length = 276
Score = 93.2 bits (230), Expect = 3e-19
Identities = 75/256 (29%), Positives = 132/256 (51%), Gaps = 15/256 (5%)
Query: 55 PKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSS---EEEHAIEITTQEITQL 111
P+ D IQ G I++ + A + + T DSS E ++ +T ++ +
Sbjct: 17 PQLRDFSSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQENLQQLQHSTNQLAKE 76
Query: 112 FHRCQRAVQALP-----SRARACSEQEGRLLGNVVASLA--QALQELSTSFRHAQSGYLK 164
+ + + +LP S R Q+ RL+ + A+L QA+Q S + +S
Sbjct: 77 TNELLKELGSLPLPLSTSEQRQQRLQKERLMNDFSAALNNFQAVQR-RVSEKEKESIARA 135
Query: 165 RMKNREERSQHFFDTSVPLMDDGDD-NTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIV 223
R +R + + + D ++ N + + ED++ + EQ+ +++ERE IRQ+
Sbjct: 136 RAGSRLSAEERQREEQLVSFDSHEEWNQMQSQ---EDEVAITEQDLELIKERETAIRQLE 192
Query: 224 QSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLV 283
I D+N+IF+DL MI +QG ++D I+ NVE S + E +QL +A YQKK+RK +
Sbjct: 193 ADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATEQLQRAAYYQKKSRKKMC 252
Query: 284 ILILFVIIIVLIVVLV 299
IL+L + +I+LI+ L+
Sbjct: 253 ILVLVLSVIILILGLI 268
>gi|4759182 syntaxin 1A (brain) [Homo sapiens]
Length = 288
Score = 85.1 bits (209), Expect = 7e-17
Identities = 69/274 (25%), Positives = 138/274 (50%), Gaps = 21/274 (7%)
Query: 42 DPEAAIGVTK-RPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHA 100
D + A+ V + R ++ + V+EI+ + +I + ++E+ H L P D+ ++EE
Sbjct: 17 DDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEE-- 74
Query: 101 IEITTQEITQLFHRCQRAVQALPSRARACSEQEG--------RLLGNVVASLAQALQELS 152
+E +I + ++ + ++++ ++ ++EG R+ ++L++ E+
Sbjct: 75 LEELMSDIKKTANKVRSKLKSIE---QSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVM 131
Query: 153 TSFRHAQSGYLKRMKNREERSQHFFD---TSVPLMD--DGDDNTLYHRGFTEDQLVLVEQ 207
+ + QS Y +R K R +R TS L D + + ++ G D + +Q
Sbjct: 132 SEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSIS-KQ 190
Query: 208 NTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQ 267
+E R EI ++ SI +L+++F D+ ++ QG ++DRI+YNVE + E +
Sbjct: 191 ALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSD 250
Query: 268 LHKAEQYQKK-NRKMLVILILFVIIIVLIVVLVG 300
KA +YQ K RK ++I+I VI+ ++I VG
Sbjct: 251 TKKAVKYQSKARRKKIMIIICCVILGIVIASTVG 284
>gi|4759184 syntaxin 3 [Homo sapiens]
Length = 289
Score = 82.4 bits (202), Expect = 4e-16
Identities = 63/286 (22%), Positives = 139/286 (48%), Gaps = 19/286 (6%)
Query: 22 QLLAEQLADDRMALVSGISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASL 81
QL A+QL D I++D A + ++ ++E + ++ +I + ++E L
Sbjct: 7 QLKAKQLTQDDDTDAVEIAIDNTAFMD-------EFFSEIEETRLNIDKISEHVEEAKKL 59
Query: 82 HDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRAR---ACSEQEGRLLG 138
+ L+ P + ++++ +E T EI + + + ++++ S + R+
Sbjct: 60 YSIILSAPIPEPKTKDD--LEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRSSADLRIRK 117
Query: 139 NVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFF-----DTSVPLMDDGDDNTLY 193
+ + L++ E+ T + AQ + +R K R +R D + M + + ++
Sbjct: 118 SQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIF 177
Query: 194 HRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYN 253
G + Q+ +Q +E R ++I ++ SI +L+++F D+ ++ QG +LD I+ N
Sbjct: 178 TSGIIDSQIS--KQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELN 235
Query: 254 VEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLV 299
V + E + KA +YQ + RK L+I+I+ V++++ I+ L+
Sbjct: 236 VMHTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALI 281
>gi|16418379 syntaxin 1B [Homo sapiens]
Length = 288
Score = 81.3 bits (199), Expect = 1e-15
Identities = 65/260 (25%), Positives = 133/260 (51%), Gaps = 22/260 (8%)
Query: 56 KWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRC 115
++ + V+EI+ + ++ + ++++ H L P D+ +++E +E T +I + ++
Sbjct: 31 EFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQE--LEDLTADIKKTANKV 88
Query: 116 QRAVQALPSRARACSEQEG--------RLLGNVVASLAQALQELSTSFRHAQSGYLKRMK 167
+ ++A+ ++ ++EG R+ ++L++ E+ T + QS Y R K
Sbjct: 89 RSKLKAIE---QSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCK 145
Query: 168 NREERSQHFFD---TSVPLMDDGDDNTLYHRGFTEDQLV---LVEQNTLMVEEREREIRQ 221
+R +R T+ L D + L FT+D + + +Q +E R EI +
Sbjct: 146 DRIQRQLEITGRTTTNEELEDMLESGKLAI--FTDDIKMDSQMTKQALNEIETRHNEIIK 203
Query: 222 IVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKK-NRK 280
+ SI +L+++F D+ ++ QG ++DRI+YNVE S E + KA +YQ K RK
Sbjct: 204 LETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRK 263
Query: 281 MLVILILFVIIIVLIVVLVG 300
++I+I V++ V++ +G
Sbjct: 264 KIMIIICCVVLGVVLASSIG 283
>gi|37577287 syntaxin 2 isoform 1 [Homo sapiens]
Length = 287
Score = 70.9 bits (172), Expect = 1e-12
Identities = 54/250 (21%), Positives = 121/250 (48%), Gaps = 15/250 (6%)
Query: 61 VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 120
V+EI+ + +I Q ++E+ H L+ P + +EE +E +EI + ++ + ++
Sbjct: 36 VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEE--LEDLNKEIKKTANKIRAKLK 93
Query: 121 ALPS-----RARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQH 175
A+ + + + R+ + L++ E + AQ+ + +R K R +R
Sbjct: 94 AIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLE 153
Query: 176 FF------DTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDL 229
D +++ G + ++ Q+ N +E R ++I ++ SI +L
Sbjct: 154 ITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNE--IESRHKDIMKLETSIREL 211
Query: 230 NEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFV 289
+E+F D+ + QG +++ I+ NV + E ++ KA +YQ K R+ L+ +I+ V
Sbjct: 212 HEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFIIICV 271
Query: 290 IIIVLIVVLV 299
I++++I+ ++
Sbjct: 272 IVLLVILGII 281
>gi|37577162 syntaxin 2 isoform 2 [Homo sapiens]
Length = 288
Score = 69.3 bits (168), Expect = 4e-12
Identities = 54/253 (21%), Positives = 121/253 (47%), Gaps = 16/253 (6%)
Query: 61 VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 120
V+EI+ + +I Q ++E+ H L+ P + +EE +E +EI + ++ + ++
Sbjct: 36 VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEE--LEDLNKEIKKTANKIRAKLK 93
Query: 121 AL-----PSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQH 175
A+ + + + R+ + L++ E + AQ+ + +R K R +R
Sbjct: 94 AIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLE 153
Query: 176 FF------DTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDL 229
D +++ G + ++ Q+ N +E R ++I ++ SI +L
Sbjct: 154 ITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNE--IESRHKDIMKLETSIREL 211
Query: 230 NEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKK-NRKMLVILILF 288
+E+F D+ + QG +++ I+ NV + E ++ KA +YQ K RK +I+ +
Sbjct: 212 HEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWIIIAVS 271
Query: 289 VIIIVLIVVLVGV 301
V+++ +I +++G+
Sbjct: 272 VVLVAIIALIIGL 284
>gi|20149560 syntaxin 4 [Homo sapiens]
Length = 297
Score = 68.9 bits (167), Expect = 5e-12
Identities = 65/261 (24%), Positives = 121/261 (46%), Gaps = 16/261 (6%)
Query: 53 PPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLF 112
P ++ V I+ + ++ K++EL L P ++S ++E ++ EI QL
Sbjct: 37 PDEEFFHKVRTIRQTIVKLGNKVQELEKQQVTILATPLPEESMKQE--LQNLRDEIKQLG 94
Query: 113 HRCQRAVQALPSRARACSEQEG----RLLGNVVASLAQALQELSTSFRHAQSGYLKRMKN 168
+ ++A+ + E R+ L+Q EL QS Y R KN
Sbjct: 95 REIRLQLKAIEPQKEEADENYNSVNTRMRKTQHGVLSQQFVELINKCNSMQSEY--REKN 152
Query: 169 REERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEE-------REREIRQ 221
E + T+ ++ D + + G +E + + ++T + + R EI+Q
Sbjct: 153 VERIRRQLKITNAGMVSDEELEQMLDSGQSEVFVSNILKDTQVTRQALNEISARHSEIQQ 212
Query: 222 IVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKM 281
+ +SI +L++IF L + QG +++RI+ N+ S E G + + A + QKK RK
Sbjct: 213 LERSIRELHDIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKK 272
Query: 282 LVILILFV-IIIVLIVVLVGV 301
V++ + V I +VL+ V++GV
Sbjct: 273 KVLIAICVSITVVLLAVIIGV 293
>gi|94400932 syntaxin 5 [Homo sapiens]
Length = 355
Score = 60.1 bits (144), Expect = 2e-09
Identities = 61/255 (23%), Positives = 107/255 (41%), Gaps = 29/255 (11%)
Query: 67 DVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRA 126
D+ K+++L L + + DD + E IE T I Q + + + L
Sbjct: 104 DLSNTFAKLEKLTILAKR---KSLFDDKAVE---IEELTYIIKQDINSLNKQIAQLQDFV 157
Query: 127 RACSEQEGRLL----GNVVASLAQALQELSTSFR---HAQSGYLKRMKNREERSQHFFDT 179
RA Q GR L +V SL L +S F+ ++ LK+ ++R E+ +
Sbjct: 158 RAKGSQSGRHLQTHSNTIVVSLQSKLASMSNDFKSVLEVRTENLKQQRSRREQFSRAPVS 217
Query: 180 SVPLMDDGDDNTLYHRGF----------------TEDQLVLVEQNTLMVEEREREIRQIV 223
++PL + G T QL L+++ ++ R ++ I
Sbjct: 218 ALPLAPNHLGGGAVVLGAESHASKDVAIDMMDSRTSQQLQLIDEQDSYIQSRADTMQNIE 277
Query: 224 QSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLV 283
+I +L IF+ L M+ EQ + RID NV + + E ++ K Q NR ++V
Sbjct: 278 STIVELGSIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAHSEILKYFQSVTSNRWLMV 337
Query: 284 ILILFVIIIVLIVVL 298
+ L +I+ +I V+
Sbjct: 338 KIFLILIVFFIIFVV 352
>gi|223972648 t-SNARE domain containing 1 [Homo sapiens]
Length = 513
Score = 52.4 bits (124), Expect = 5e-07
Identities = 58/278 (20%), Positives = 113/278 (40%), Gaps = 28/278 (10%)
Query: 38 GISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEE 97
G SL+P A T+ P + E+ +V RI + SL + T D+ E
Sbjct: 241 GFSLEPPRA---TQVDPCNLQELFQEMSANVFRINSSV---TSLERSLQSLGTPSDTQEL 294
Query: 98 EHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRH 157
++ QE + +V+ + R+ QE + L L T
Sbjct: 295 RDSLHTAQQETNKTIAASASSVKQMAELLRSSCPQER------LQQERPQLDRLKTQLSD 348
Query: 158 AQSGYLKRMKNREERSQHFFDTS---------VPLMDDGDDNTLYHRGFT----EDQLVL 204
A Y K E+S+ + P + DD +++ ++Q +L
Sbjct: 349 AIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQAPFAELADDEKVFNGSDNMWQGQEQALL 408
Query: 205 ---VEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKT 261
E++ + RE I Q+ ++ D+N+I +DL +M+ EQG +D I+ ++E +
Sbjct: 409 PDITEEDLEAIRLREEAILQMESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHA 468
Query: 262 EDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLV 299
E + L A ++Q + K+ + + +L+++++
Sbjct: 469 EAARQLLAGASRHQLQRHKIKCCFLSAGVTALLVIIII 506
>gi|33667038 syntaxin 11 [Homo sapiens]
Length = 287
Score = 48.1 bits (113), Expect = 9e-06
Identities = 54/225 (24%), Positives = 102/225 (45%), Gaps = 25/225 (11%)
Query: 67 DVGRI-KQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSR 125
DV R+ KQ + L S+ L + ++I + ++ H RA++ L
Sbjct: 61 DVKRLGKQNARFLTSMR-------RLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEA 113
Query: 126 ARACSEQEGRLLGNVVASLAQA-LQELSTSFRHAQSGY----LKRMKNREERSQHFFDTS 180
A A Q G + VA +++A L+ +F+ A Y +K+ N + R Q +
Sbjct: 114 AEA---QHGP--HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIM 168
Query: 181 VPLMDDGDDNTLYHRG----FTEDQLVLVEQNTLM---VEEREREIRQIVQSISDLNEIF 233
+ ++ +G F+E+ L V+ +E R RE+ ++ I D++E+F
Sbjct: 169 GKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELF 228
Query: 234 RDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKN 278
+ ++ +Q L+ I+ NV+++ T Q+ KA QY++KN
Sbjct: 229 LQMAVLVEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKN 273
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 44.3 bits (103), Expect = 1e-04
Identities = 60/275 (21%), Positives = 112/275 (40%), Gaps = 30/275 (10%)
Query: 13 LRNNSIQNRQLLAEQLADDRMALVSGISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIK 72
L +N R+ +E+L D+ L S + EA I + K V ++ ++K
Sbjct: 236 LMDNMTLERERESEKLKDECKKLQSQYA-SSEATISQLRSELAKGPQEVAVYVQELQKLK 294
Query: 73 QKMKELA----SLHDKHLNRPTLDDSSEEEHAIE-ITTQEITQLFHRCQRAVQALPSRAR 127
+ EL +L + L + EE+H E ++ + I H+ Q L SR
Sbjct: 295 SSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLS 354
Query: 128 ACSEQEGRL------LGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTSV 181
A R+ G L + L E+ T ++H ++ + + + REE+ QH
Sbjct: 355 ASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQH------ 408
Query: 182 PLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIV---QSISDLNEIFRDLGA 238
L + N L H E + L E + + E+R+ +++ Q ++DL L
Sbjct: 409 GLQLQSEINQL-HSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEE 467
Query: 239 MIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQ 273
+ E+ T + + ++++ KQ H+ +Q
Sbjct: 468 QLKEKVTNSTELQHQLDKT--------KQQHQEQQ 494
>gi|49258196 syntaxin 19 [Homo sapiens]
Length = 294
Score = 40.8 bits (94), Expect = 0.002
Identities = 25/102 (24%), Positives = 51/102 (50%), Gaps = 7/102 (6%)
Query: 184 MDDGDDNTLYHRGFTE--DQLVLVEQNTLM-----VEEREREIRQIVQSISDLNEIFRDL 236
M + D N + H+G E ++ +L E N +E+R +E+ + I DL ++F +
Sbjct: 177 MSEEDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQI 236
Query: 237 GAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKN 278
++ EQG ++ I+ V + + ++ A +Y+K+N
Sbjct: 237 SLLVEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRN 278
>gi|4507285 syntaxin 10 [Homo sapiens]
Length = 249
Score = 38.1 bits (87), Expect = 0.010
Identities = 18/89 (20%), Positives = 48/89 (53%)
Query: 210 LMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLH 269
L+++E+++++ + SI L + +G + EQG +LD ++ + + + L++L
Sbjct: 158 LIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLA 217
Query: 270 KAEQYQKKNRKMLVILILFVIIIVLIVVL 298
K R+ I +L ++++++++L
Sbjct: 218 KVSHMTSDRRQWCAIAVLVGVLLLVLILL 246
>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
[Homo sapiens]
Length = 8749
Score = 37.7 bits (86), Expect = 0.013
Identities = 45/179 (25%), Positives = 79/179 (44%), Gaps = 42/179 (23%)
Query: 101 IEITTQEITQLFHRCQRAVQALPSRA--RACSEQEG-RLLGNVVASLAQALQELSTSFRH 157
IE+TTQ +++L + R + A A S Q+G R + + VA L +A+ EL+
Sbjct: 4609 IELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGEAVDELN----- 4663
Query: 158 AQSGYLKRMKNREERSQHFFDTSVPLMDDGDDN--TLYHR--GFTEDQLVLVEQNTL--- 210
++ + F T P D + TLYHR TE ++ L+E T
Sbjct: 4664 -------------QKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQ 4710
Query: 211 ----MVEEREREIRQIVQSISDLNE----------IFRDLGAMIVEQGTVLDRIDYNVE 255
M ++ ER+++ + + S +NE ++ L + + G VL R+ ++E
Sbjct: 4711 EHEKMCQQLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLE 4769
>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
[Homo sapiens]
Length = 8797
Score = 37.7 bits (86), Expect = 0.013
Identities = 45/179 (25%), Positives = 79/179 (44%), Gaps = 42/179 (23%)
Query: 101 IEITTQEITQLFHRCQRAVQALPSRA--RACSEQEG-RLLGNVVASLAQALQELSTSFRH 157
IE+TTQ +++L + R + A A S Q+G R + + VA L +A+ EL+
Sbjct: 4680 IELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGEAVDELN----- 4734
Query: 158 AQSGYLKRMKNREERSQHFFDTSVPLMDDGDDN--TLYHR--GFTEDQLVLVEQNTL--- 210
++ + F T P D + TLYHR TE ++ L+E T
Sbjct: 4735 -------------QKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQ 4781
Query: 211 ----MVEEREREIRQIVQSISDLNE----------IFRDLGAMIVEQGTVLDRIDYNVE 255
M ++ ER+++ + + S +NE ++ L + + G VL R+ ++E
Sbjct: 4782 EHEKMCQQLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLE 4840
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 37.7 bits (86), Expect = 0.013
Identities = 61/273 (22%), Positives = 113/273 (41%), Gaps = 41/273 (15%)
Query: 19 QNRQLLAEQLADDRMALVSGISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKEL 78
Q RQLL E+LA L EAA KR E++ ++ +++ +M+ L
Sbjct: 1727 QQRQLLEEELA----------RLQREAAAATQKR---------QELEAELAKVRAEMEVL 1767
Query: 79 --ASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEG-- 134
+ + +R T + S + A +E+ + R RA+ R R +E++
Sbjct: 1768 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARL-RALAEEAKRQRQLAEEDAAR 1826
Query: 135 ------RLLGNVVASLAQALQ-----ELSTSFRHAQSGYLKRMKNREE-RSQHFFDTSVP 182
R+L +A++ +A + E++ + A++ L+R+ E + + + +
Sbjct: 1827 QRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQ 1886
Query: 183 LMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVE 242
D ++ R ++ +L E+ +VE+ R+ RQ+ + I L F A E
Sbjct: 1887 HKADIEERLAQLRKASDSEL---ERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAE 1943
Query: 243 QGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQ 275
L RI N E + E +L A Q Q
Sbjct: 1944 LELELGRIRSNAEDTLRSKEQA--ELEAARQRQ 1974
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 37.7 bits (86), Expect = 0.013
Identities = 61/273 (22%), Positives = 113/273 (41%), Gaps = 41/273 (15%)
Query: 19 QNRQLLAEQLADDRMALVSGISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKEL 78
Q RQLL E+LA L EAA KR E++ ++ +++ +M+ L
Sbjct: 1731 QQRQLLEEELA----------RLQREAAAATQKR---------QELEAELAKVRAEMEVL 1771
Query: 79 --ASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEG-- 134
+ + +R T + S + A +E+ + R RA+ R R +E++
Sbjct: 1772 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARL-RALAEEAKRQRQLAEEDAAR 1830
Query: 135 ------RLLGNVVASLAQALQ-----ELSTSFRHAQSGYLKRMKNREE-RSQHFFDTSVP 182
R+L +A++ +A + E++ + A++ L+R+ E + + + +
Sbjct: 1831 QRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQ 1890
Query: 183 LMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVE 242
D ++ R ++ +L E+ +VE+ R+ RQ+ + I L F A E
Sbjct: 1891 HKADIEERLAQLRKASDSEL---ERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAE 1947
Query: 243 QGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQ 275
L RI N E + E +L A Q Q
Sbjct: 1948 LELELGRIRSNAEDTLRSKEQA--ELEAARQRQ 1978
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 37.7 bits (86), Expect = 0.013
Identities = 61/273 (22%), Positives = 113/273 (41%), Gaps = 41/273 (15%)
Query: 19 QNRQLLAEQLADDRMALVSGISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKEL 78
Q RQLL E+LA L EAA KR E++ ++ +++ +M+ L
Sbjct: 1727 QQRQLLEEELA----------RLQREAAAATQKR---------QELEAELAKVRAEMEVL 1767
Query: 79 --ASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEG-- 134
+ + +R T + S + A +E+ + R RA+ R R +E++
Sbjct: 1768 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARL-RALAEEAKRQRQLAEEDAAR 1826
Query: 135 ------RLLGNVVASLAQALQ-----ELSTSFRHAQSGYLKRMKNREE-RSQHFFDTSVP 182
R+L +A++ +A + E++ + A++ L+R+ E + + + +
Sbjct: 1827 QRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQ 1886
Query: 183 LMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVE 242
D ++ R ++ +L E+ +VE+ R+ RQ+ + I L F A E
Sbjct: 1887 HKADIEERLAQLRKASDSEL---ERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAE 1943
Query: 243 QGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQ 275
L RI N E + E +L A Q Q
Sbjct: 1944 LELELGRIRSNAEDTLRSKEQA--ELEAARQRQ 1974
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 37.7 bits (86), Expect = 0.013
Identities = 61/273 (22%), Positives = 113/273 (41%), Gaps = 41/273 (15%)
Query: 19 QNRQLLAEQLADDRMALVSGISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKEL 78
Q RQLL E+LA L EAA KR E++ ++ +++ +M+ L
Sbjct: 1695 QQRQLLEEELA----------RLQREAAAATQKR---------QELEAELAKVRAEMEVL 1735
Query: 79 --ASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEG-- 134
+ + +R T + S + A +E+ + R RA+ R R +E++
Sbjct: 1736 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARL-RALAEEAKRQRQLAEEDAAR 1794
Query: 135 ------RLLGNVVASLAQALQ-----ELSTSFRHAQSGYLKRMKNREE-RSQHFFDTSVP 182
R+L +A++ +A + E++ + A++ L+R+ E + + + +
Sbjct: 1795 QRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQ 1854
Query: 183 LMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVE 242
D ++ R ++ +L E+ +VE+ R+ RQ+ + I L F A E
Sbjct: 1855 HKADIEERLAQLRKASDSEL---ERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAE 1911
Query: 243 QGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQ 275
L RI N E + E +L A Q Q
Sbjct: 1912 LELELGRIRSNAEDTLRSKEQA--ELEAARQRQ 1942
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 37.7 bits (86), Expect = 0.013
Identities = 61/273 (22%), Positives = 113/273 (41%), Gaps = 41/273 (15%)
Query: 19 QNRQLLAEQLADDRMALVSGISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKEL 78
Q RQLL E+LA L EAA KR E++ ++ +++ +M+ L
Sbjct: 1864 QQRQLLEEELA----------RLQREAAAATQKR---------QELEAELAKVRAEMEVL 1904
Query: 79 --ASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEG-- 134
+ + +R T + S + A +E+ + R RA+ R R +E++
Sbjct: 1905 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARL-RALAEEAKRQRQLAEEDAAR 1963
Query: 135 ------RLLGNVVASLAQALQ-----ELSTSFRHAQSGYLKRMKNREE-RSQHFFDTSVP 182
R+L +A++ +A + E++ + A++ L+R+ E + + + +
Sbjct: 1964 QRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQ 2023
Query: 183 LMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVE 242
D ++ R ++ +L E+ +VE+ R+ RQ+ + I L F A E
Sbjct: 2024 HKADIEERLAQLRKASDSEL---ERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAE 2080
Query: 243 QGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQ 275
L RI N E + E +L A Q Q
Sbjct: 2081 LELELGRIRSNAEDTLRSKEQA--ELEAARQRQ 2111
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 37.7 bits (86), Expect = 0.013
Identities = 61/273 (22%), Positives = 113/273 (41%), Gaps = 41/273 (15%)
Query: 19 QNRQLLAEQLADDRMALVSGISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKEL 78
Q RQLL E+LA L EAA KR E++ ++ +++ +M+ L
Sbjct: 1705 QQRQLLEEELA----------RLQREAAAATQKR---------QELEAELAKVRAEMEVL 1745
Query: 79 --ASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEG-- 134
+ + +R T + S + A +E+ + R RA+ R R +E++
Sbjct: 1746 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARL-RALAEEAKRQRQLAEEDAAR 1804
Query: 135 ------RLLGNVVASLAQALQ-----ELSTSFRHAQSGYLKRMKNREE-RSQHFFDTSVP 182
R+L +A++ +A + E++ + A++ L+R+ E + + + +
Sbjct: 1805 QRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQ 1864
Query: 183 LMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVE 242
D ++ R ++ +L E+ +VE+ R+ RQ+ + I L F A E
Sbjct: 1865 HKADIEERLAQLRKASDSEL---ERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAE 1921
Query: 243 QGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQ 275
L RI N E + E +L A Q Q
Sbjct: 1922 LELELGRIRSNAEDTLRSKEQA--ELEAARQRQ 1952
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 37.7 bits (86), Expect = 0.013
Identities = 61/273 (22%), Positives = 113/273 (41%), Gaps = 41/273 (15%)
Query: 19 QNRQLLAEQLADDRMALVSGISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKEL 78
Q RQLL E+LA L EAA KR E++ ++ +++ +M+ L
Sbjct: 1713 QQRQLLEEELA----------RLQREAAAATQKR---------QELEAELAKVRAEMEVL 1753
Query: 79 --ASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEG-- 134
+ + +R T + S + A +E+ + R RA+ R R +E++
Sbjct: 1754 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARL-RALAEEAKRQRQLAEEDAAR 1812
Query: 135 ------RLLGNVVASLAQALQ-----ELSTSFRHAQSGYLKRMKNREE-RSQHFFDTSVP 182
R+L +A++ +A + E++ + A++ L+R+ E + + + +
Sbjct: 1813 QRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQ 1872
Query: 183 LMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVE 242
D ++ R ++ +L E+ +VE+ R+ RQ+ + I L F A E
Sbjct: 1873 HKADIEERLAQLRKASDSEL---ERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAE 1929
Query: 243 QGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQ 275
L RI N E + E +L A Q Q
Sbjct: 1930 LELELGRIRSNAEDTLRSKEQA--ELEAARQRQ 1960
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 37.7 bits (86), Expect = 0.013
Identities = 61/273 (22%), Positives = 113/273 (41%), Gaps = 41/273 (15%)
Query: 19 QNRQLLAEQLADDRMALVSGISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKEL 78
Q RQLL E+LA L EAA KR E++ ++ +++ +M+ L
Sbjct: 1754 QQRQLLEEELA----------RLQREAAAATQKR---------QELEAELAKVRAEMEVL 1794
Query: 79 --ASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEG-- 134
+ + +R T + S + A +E+ + R RA+ R R +E++
Sbjct: 1795 LASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARL-RALAEEAKRQRQLAEEDAAR 1853
Query: 135 ------RLLGNVVASLAQALQ-----ELSTSFRHAQSGYLKRMKNREE-RSQHFFDTSVP 182
R+L +A++ +A + E++ + A++ L+R+ E + + + +
Sbjct: 1854 QRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQ 1913
Query: 183 LMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVE 242
D ++ R ++ +L E+ +VE+ R+ RQ+ + I L F A E
Sbjct: 1914 HKADIEERLAQLRKASDSEL---ERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAE 1970
Query: 243 QGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQ 275
L RI N E + E +L A Q Q
Sbjct: 1971 LELELGRIRSNAEDTLRSKEQA--ELEAARQRQ 2001
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 36.6 bits (83), Expect = 0.028
Identities = 45/203 (22%), Positives = 83/203 (40%), Gaps = 25/203 (12%)
Query: 82 HDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVV 141
H+K L EE AI + Q+FH+ Q A +L + A + EG+ V+
Sbjct: 335 HEKQDTLVALRQQLEEVKAINL------QMFHKAQNAESSLQQKNEAITSFEGK-TNQVM 387
Query: 142 ASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQ 201
+S+ Q + L S R Q + K ++E + L + + + ++
Sbjct: 388 SSMKQMEERLQHSERARQGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEK 447
Query: 202 LVLVEQNTLMVEERERE------IRQIVQSISDLNEIFR-------DLGAMIVEQGTVLD 248
EQ + E + E +R +Q + L + R +L + EQ L
Sbjct: 448 ----EQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEEQEQALQ 503
Query: 249 RIDYNVEQSCIKTEDGLKQLHKA 271
+ ++ QS +K ED +K++++A
Sbjct: 504 EMGLHLSQSKLKMED-IKEVNQA 525
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 36.6 bits (83), Expect = 0.028
Identities = 45/203 (22%), Positives = 83/203 (40%), Gaps = 25/203 (12%)
Query: 82 HDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVV 141
H+K L EE AI + Q+FH+ Q A +L + A + EG+ V+
Sbjct: 335 HEKQDTLVALRQQLEEVKAINL------QMFHKAQNAESSLQQKNEAITSFEGK-TNQVM 387
Query: 142 ASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQ 201
+S+ Q + L S R Q + K ++E + L + + + ++
Sbjct: 388 SSMKQMEERLQHSERARQGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEK 447
Query: 202 LVLVEQNTLMVEERERE------IRQIVQSISDLNEIFR-------DLGAMIVEQGTVLD 248
EQ + E + E +R +Q + L + R +L + EQ L
Sbjct: 448 ----EQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEEQEQALQ 503
Query: 249 RIDYNVEQSCIKTEDGLKQLHKA 271
+ ++ QS +K ED +K++++A
Sbjct: 504 EMGLHLSQSKLKMED-IKEVNQA 525
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,011,494
Number of Sequences: 37866
Number of extensions: 403347
Number of successful extensions: 1840
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 65
Number of HSP's that attempted gapping in prelim test: 1759
Number of HSP's gapped (non-prelim): 147
length of query: 304
length of database: 18,247,518
effective HSP length: 102
effective length of query: 202
effective length of database: 14,385,186
effective search space: 2905807572
effective search space used: 2905807572
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.