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Search of human proteins with 33589818
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33589818 prolyl 4-hydroxylase, alpha III subunit precursor
[Homo sapiens]
(544 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33589818 prolyl 4-hydroxylase, alpha III subunit precursor [H... 1095 0.0
gi|217272863 prolyl 4-hydroxylase, alpha II subunit isoform 1 pr... 329 5e-90
gi|4758868 prolyl 4-hydroxylase, alpha II subunit isoform 1 prec... 329 5e-90
gi|217272861 prolyl 4-hydroxylase, alpha II subunit isoform 2 pr... 327 2e-89
gi|63252893 prolyl 4-hydroxylase, alpha II subunit isoform 2 pre... 327 2e-89
gi|63252891 prolyl 4-hydroxylase, alpha II subunit isoform 2 pre... 327 2e-89
gi|63252886 prolyl 4-hydroxylase, alpha I subunit isoform 1 prec... 324 1e-88
gi|217272849 prolyl 4-hydroxylase, alpha I subunit isoform 2 pre... 323 3e-88
gi|63252888 prolyl 4-hydroxylase, alpha I subunit isoform 2 prec... 323 3e-88
gi|217272851 prolyl 4-hydroxylase, alpha I subunit isoform 3 pre... 285 1e-76
gi|29570771 hypoxia-inducible factor prolyl 4-hydroxylase isofor... 68 2e-11
gi|64085083 hypoxia-inducible factor prolyl 4-hydroxylase isofor... 50 7e-06
gi|5453601 cartilage associated protein precursor [Homo sapiens] 42 0.002
gi|197313662 leprecan-like 1 isoform b [Homo sapiens] 40 0.004
gi|27764882 leprecan-like 1 isoform a [Homo sapiens] 40 0.004
gi|186928835 leprecan 1 isoform 1 [Homo sapiens] 37 0.046
gi|226371643 leprecan 1 isoform 2 [Homo sapiens] 37 0.046
gi|18921093 transient receptor potential cation channel, subfami... 31 3.3
gi|17402888 neuronal pentraxin receptor [Homo sapiens] 31 3.3
gi|125628636 keratin 80 isoform a [Homo sapiens] 30 4.3
gi|125628632 keratin 80 isoform b [Homo sapiens] 30 4.3
gi|31317256 X-linked neuroligin 4 [Homo sapiens] 30 7.4
gi|24308209 X-linked neuroligin 4 [Homo sapiens] 30 7.4
gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens] 30 7.4
gi|51093834 hypothetical protein LOC126859 isoform 2 [Homo sapiens] 30 7.4
gi|7705433 eukaryotic translation initiation factor 3 subunit 6 ... 30 7.4
gi|40538788 neuroligin 4, Y-linked [Homo sapiens] 30 7.4
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 30 7.4
gi|115387118 hypothetical protein LOC57562 [Homo sapiens] 30 7.4
gi|37537710 La ribonucleoprotein domain family, member 6 isoform... 29 9.6
>gi|33589818 prolyl 4-hydroxylase, alpha III subunit precursor [Homo
sapiens]
Length = 544
Score = 1095 bits (2833), Expect = 0.0
Identities = 544/544 (100%), Positives = 544/544 (100%)
Query: 1 MGPGARLAALLAVLALGTGDPERAAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEA 60
MGPGARLAALLAVLALGTGDPERAAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEA
Sbjct: 1 MGPGARLAALLAVLALGTGDPERAAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEA 60
Query: 61 RLRDLTRFYDKVLSLHEDSTTPVANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGY 120
RLRDLTRFYDKVLSLHEDSTTPVANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGY
Sbjct: 61 RLRDLTRFYDKVLSLHEDSTTPVANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGY 120
Query: 121 EKVEQDLPAFEDLEGAARALMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLT 180
EKVEQDLPAFEDLEGAARALMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLT
Sbjct: 121 EKVEQDLPAFEDLEGAARALMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLT 180
Query: 181 GDDCFQVGKVAYDMGDYYHAIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRA 240
GDDCFQVGKVAYDMGDYYHAIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRA
Sbjct: 181 GDDCFQVGKVAYDMGDYYHAIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRA 240
Query: 241 GNVSCALSLSREFLLYSPDNKRMARNVLKYERLLAESPNHVVAEAVIQRPNIPHLQTRDT 300
GNVSCALSLSREFLLYSPDNKRMARNVLKYERLLAESPNHVVAEAVIQRPNIPHLQTRDT
Sbjct: 241 GNVSCALSLSREFLLYSPDNKRMARNVLKYERLLAESPNHVVAEAVIQRPNIPHLQTRDT 300
Query: 301 YEGLCQTLGSQPTLYQIPSLYCSYETNSNAYLLLQPIRKEVIHLEPYIALYHDFVSDSEA 360
YEGLCQTLGSQPTLYQIPSLYCSYETNSNAYLLLQPIRKEVIHLEPYIALYHDFVSDSEA
Sbjct: 301 YEGLCQTLGSQPTLYQIPSLYCSYETNSNAYLLLQPIRKEVIHLEPYIALYHDFVSDSEA 360
Query: 361 QKIRELAEPWLQRSVVASGEKQLQVEYRISKSAWLKDTVDPKLVTLNHRIAALTGLDVRP 420
QKIRELAEPWLQRSVVASGEKQLQVEYRISKSAWLKDTVDPKLVTLNHRIAALTGLDVRP
Sbjct: 361 QKIRELAEPWLQRSVVASGEKQLQVEYRISKSAWLKDTVDPKLVTLNHRIAALTGLDVRP 420
Query: 421 PYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYRMKSGNRVATFMIYLSSVEAGGATAFIY 480
PYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYRMKSGNRVATFMIYLSSVEAGGATAFIY
Sbjct: 421 PYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYRMKSGNRVATFMIYLSSVEAGGATAFIY 480
Query: 481 ANLSVPVVRNAALFWWNLHRSGEGDSDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCSS 540
ANLSVPVVRNAALFWWNLHRSGEGDSDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCSS
Sbjct: 481 ANLSVPVVRNAALFWWNLHRSGEGDSDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCSS 540
Query: 541 SPED 544
SPED
Sbjct: 541 SPED 544
>gi|217272863 prolyl 4-hydroxylase, alpha II subunit isoform 1
precursor [Homo sapiens]
Length = 535
Score = 329 bits (843), Expect = 5e-90
Identities = 197/539 (36%), Positives = 301/539 (55%), Gaps = 38/539 (7%)
Query: 24 AAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKVLSLHEDSTTP- 82
+ + + F+++ + + E+ L+ L+ Y+ EEA+L + + +K+ +L S
Sbjct: 17 SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWANKMEALTSKSAADA 76
Query: 83 ---VANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGYEKVEQDLPAFEDLEGAARA 139
+A+P+ A+ L+KRL +DW + L ++ Q P ED GAA+A
Sbjct: 77 EGYLAHPVNAYKLVKRLNTDWP-ALEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKA 135
Query: 140 LMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLTGDDCFQVGKVAYDMGDYYH 199
LMRLQD Y L+ ++RG +L K L+ DDCF +G+ AY+ GDYYH
Sbjct: 136 LMRLQDTYRLDPGTISRG-----------ELPGTKYQAMLSVDDCFGMGRSAYNEGDYYH 184
Query: 200 AIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRAGNVSCALSLSREFLLYSPD 259
+ W+E+ + GE T ++ + LD+L++A F+ G++ AL L+R L P
Sbjct: 185 TVLWMEQVLKQLDA--GEEATTTKSQV---LDYLSYAVFQLGDLHRALELTRRLLSLDPS 239
Query: 260 NKRMARNVLKYERLLAESPNHVVA----------EAVIQRPNIPHLQTRDTYEGLCQTLG 309
++R N+ +E+LL E + E + +RP + +L RD YE LC+ G
Sbjct: 240 HERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERP-VDYLPERDVYESLCRGEG 298
Query: 310 SQPTLYQIPSLYCSYETNSNA-YLLLQPIRKEVIHLEPYIALYHDFVSDSEAQKIRELAE 368
+ T + L+C Y + A LL+ P ++E P+I Y+D +SD E ++I+E+A+
Sbjct: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358
Query: 369 PWLQRSVVASGEKQLQV--EYRISKSAWLKDTVDPKLVTLNHRIAALTGLDVRPPYAEYL 426
P L R+ V + + YR+SKS+WL++ DP + +N R+ +TGL V+ AE L
Sbjct: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKT--AELL 416
Query: 427 QVVNYGIGGHYEPHFDHATSPSSPLYR-MKSGNRVATFMIYLSSVEAGGATAFIYANLSV 485
QV NYG+GG YEPHFD + + ++ + +GNRVATF+ Y+S VEAGGAT F ++
Sbjct: 417 QVANYGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAI 476
Query: 486 PVVRNAALFWWNLHRSGEGDSDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCSSSPED 544
+ A+FW+NL RSGEGD T HA CPVLVG KWV+NKW HE GQEF RPC S+ D
Sbjct: 477 WPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 535
>gi|4758868 prolyl 4-hydroxylase, alpha II subunit isoform 1
precursor [Homo sapiens]
Length = 535
Score = 329 bits (843), Expect = 5e-90
Identities = 197/539 (36%), Positives = 301/539 (55%), Gaps = 38/539 (7%)
Query: 24 AAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKVLSLHEDSTTP- 82
+ + + F+++ + + E+ L+ L+ Y+ EEA+L + + +K+ +L S
Sbjct: 17 SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWANKMEALTSKSAADA 76
Query: 83 ---VANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGYEKVEQDLPAFEDLEGAARA 139
+A+P+ A+ L+KRL +DW + L ++ Q P ED GAA+A
Sbjct: 77 EGYLAHPVNAYKLVKRLNTDWP-ALEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKA 135
Query: 140 LMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLTGDDCFQVGKVAYDMGDYYH 199
LMRLQD Y L+ ++RG +L K L+ DDCF +G+ AY+ GDYYH
Sbjct: 136 LMRLQDTYRLDPGTISRG-----------ELPGTKYQAMLSVDDCFGMGRSAYNEGDYYH 184
Query: 200 AIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRAGNVSCALSLSREFLLYSPD 259
+ W+E+ + GE T ++ + LD+L++A F+ G++ AL L+R L P
Sbjct: 185 TVLWMEQVLKQLDA--GEEATTTKSQV---LDYLSYAVFQLGDLHRALELTRRLLSLDPS 239
Query: 260 NKRMARNVLKYERLLAESPNHVVA----------EAVIQRPNIPHLQTRDTYEGLCQTLG 309
++R N+ +E+LL E + E + +RP + +L RD YE LC+ G
Sbjct: 240 HERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERP-VDYLPERDVYESLCRGEG 298
Query: 310 SQPTLYQIPSLYCSYETNSNA-YLLLQPIRKEVIHLEPYIALYHDFVSDSEAQKIRELAE 368
+ T + L+C Y + A LL+ P ++E P+I Y+D +SD E ++I+E+A+
Sbjct: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358
Query: 369 PWLQRSVVASGEKQLQV--EYRISKSAWLKDTVDPKLVTLNHRIAALTGLDVRPPYAEYL 426
P L R+ V + + YR+SKS+WL++ DP + +N R+ +TGL V+ AE L
Sbjct: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKT--AELL 416
Query: 427 QVVNYGIGGHYEPHFDHATSPSSPLYR-MKSGNRVATFMIYLSSVEAGGATAFIYANLSV 485
QV NYG+GG YEPHFD + + ++ + +GNRVATF+ Y+S VEAGGAT F ++
Sbjct: 417 QVANYGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAI 476
Query: 486 PVVRNAALFWWNLHRSGEGDSDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCSSSPED 544
+ A+FW+NL RSGEGD T HA CPVLVG KWV+NKW HE GQEF RPC S+ D
Sbjct: 477 WPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 535
>gi|217272861 prolyl 4-hydroxylase, alpha II subunit isoform 2
precursor [Homo sapiens]
Length = 533
Score = 327 bits (837), Expect = 2e-89
Identities = 197/538 (36%), Positives = 299/538 (55%), Gaps = 38/538 (7%)
Query: 24 AAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKVLSLHEDSTTP- 82
+ + + F+++ + + E+ L+ L+ Y+ EEA+L + + +K+ +L S
Sbjct: 17 SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWANKMEALTSKSAADA 76
Query: 83 ---VANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGYEKVEQDLPAFEDLEGAARA 139
+A+P+ A+ L+KRL +DW + L ++ Q P ED GAA+A
Sbjct: 77 EGYLAHPVNAYKLVKRLNTDWP-ALEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKA 135
Query: 140 LMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLTGDDCFQVGKVAYDMGDYYH 199
LMRLQD Y L+ ++RG +L K L+ DDCF +G+ AY+ GDYYH
Sbjct: 136 LMRLQDTYRLDPGTISRG-----------ELPGTKYQAMLSVDDCFGMGRSAYNEGDYYH 184
Query: 200 AIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRAGNVSCALSLSREFLLYSPD 259
+ W+E+ + GE T ++ + LD+L++A F+ G++ AL L+R L P
Sbjct: 185 TVLWMEQVLKQLDA--GEEATTTKSQV---LDYLSYAVFQLGDLHRALELTRRLLSLDPS 239
Query: 260 NKRMARNVLKYERLLAESPNHVVA----------EAVIQRPNIPHLQTRDTYEGLCQTLG 309
++R N+ +E+LL E + E + +RP + +L RD YE LC+ G
Sbjct: 240 HERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERP-VDYLPERDVYESLCRGEG 298
Query: 310 SQPTLYQIPSLYCSYETNSNA-YLLLQPIRKEVIHLEPYIALYHDFVSDSEAQKIRELAE 368
+ T + L+C Y + A LL+ P ++E P+I Y+D +SD E ++I+E+A+
Sbjct: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358
Query: 369 PWLQRSVVASGEKQLQV--EYRISKSAWLKDTVDPKLVTLNHRIAALTGLDVRPPYAEYL 426
P L R+ V + + YR+SKS+WL++ DP + +N R+ +TGL V+ AE L
Sbjct: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKT--AELL 416
Query: 427 QVVNYGIGGHYEPHFDHATSPSSPLYRMKSGNRVATFMIYLSSVEAGGATAFIYANLSVP 486
QV NYG+GG YEPHFD + P + + GNR+ATF+ Y+S VEAGGAT F ++
Sbjct: 417 QVANYGVGGQYEPHFDFSRRPFDSGLKTE-GNRLATFLNYMSDVEAGGATVFPDLGAAIW 475
Query: 487 VVRNAALFWWNLHRSGEGDSDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCSSSPED 544
+ A+FW+NL RSGEGD T HA CPVLVG KWV+NKW HE GQEF RPC S+ D
Sbjct: 476 PKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533
>gi|63252893 prolyl 4-hydroxylase, alpha II subunit isoform 2
precursor [Homo sapiens]
Length = 533
Score = 327 bits (837), Expect = 2e-89
Identities = 197/538 (36%), Positives = 299/538 (55%), Gaps = 38/538 (7%)
Query: 24 AAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKVLSLHEDSTTP- 82
+ + + F+++ + + E+ L+ L+ Y+ EEA+L + + +K+ +L S
Sbjct: 17 SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWANKMEALTSKSAADA 76
Query: 83 ---VANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGYEKVEQDLPAFEDLEGAARA 139
+A+P+ A+ L+KRL +DW + L ++ Q P ED GAA+A
Sbjct: 77 EGYLAHPVNAYKLVKRLNTDWP-ALEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKA 135
Query: 140 LMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLTGDDCFQVGKVAYDMGDYYH 199
LMRLQD Y L+ ++RG +L K L+ DDCF +G+ AY+ GDYYH
Sbjct: 136 LMRLQDTYRLDPGTISRG-----------ELPGTKYQAMLSVDDCFGMGRSAYNEGDYYH 184
Query: 200 AIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRAGNVSCALSLSREFLLYSPD 259
+ W+E+ + GE T ++ + LD+L++A F+ G++ AL L+R L P
Sbjct: 185 TVLWMEQVLKQLDA--GEEATTTKSQV---LDYLSYAVFQLGDLHRALELTRRLLSLDPS 239
Query: 260 NKRMARNVLKYERLLAESPNHVVA----------EAVIQRPNIPHLQTRDTYEGLCQTLG 309
++R N+ +E+LL E + E + +RP + +L RD YE LC+ G
Sbjct: 240 HERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERP-VDYLPERDVYESLCRGEG 298
Query: 310 SQPTLYQIPSLYCSYETNSNA-YLLLQPIRKEVIHLEPYIALYHDFVSDSEAQKIRELAE 368
+ T + L+C Y + A LL+ P ++E P+I Y+D +SD E ++I+E+A+
Sbjct: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358
Query: 369 PWLQRSVVASGEKQLQV--EYRISKSAWLKDTVDPKLVTLNHRIAALTGLDVRPPYAEYL 426
P L R+ V + + YR+SKS+WL++ DP + +N R+ +TGL V+ AE L
Sbjct: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKT--AELL 416
Query: 427 QVVNYGIGGHYEPHFDHATSPSSPLYRMKSGNRVATFMIYLSSVEAGGATAFIYANLSVP 486
QV NYG+GG YEPHFD + P + + GNR+ATF+ Y+S VEAGGAT F ++
Sbjct: 417 QVANYGVGGQYEPHFDFSRRPFDSGLKTE-GNRLATFLNYMSDVEAGGATVFPDLGAAIW 475
Query: 487 VVRNAALFWWNLHRSGEGDSDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCSSSPED 544
+ A+FW+NL RSGEGD T HA CPVLVG KWV+NKW HE GQEF RPC S+ D
Sbjct: 476 PKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533
>gi|63252891 prolyl 4-hydroxylase, alpha II subunit isoform 2
precursor [Homo sapiens]
Length = 533
Score = 327 bits (837), Expect = 2e-89
Identities = 197/538 (36%), Positives = 299/538 (55%), Gaps = 38/538 (7%)
Query: 24 AAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKVLSLHEDSTTP- 82
+ + + F+++ + + E+ L+ L+ Y+ EEA+L + + +K+ +L S
Sbjct: 17 SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWANKMEALTSKSAADA 76
Query: 83 ---VANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGYEKVEQDLPAFEDLEGAARA 139
+A+P+ A+ L+KRL +DW + L ++ Q P ED GAA+A
Sbjct: 77 EGYLAHPVNAYKLVKRLNTDWP-ALEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKA 135
Query: 140 LMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLTGDDCFQVGKVAYDMGDYYH 199
LMRLQD Y L+ ++RG +L K L+ DDCF +G+ AY+ GDYYH
Sbjct: 136 LMRLQDTYRLDPGTISRG-----------ELPGTKYQAMLSVDDCFGMGRSAYNEGDYYH 184
Query: 200 AIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRAGNVSCALSLSREFLLYSPD 259
+ W+E+ + GE T ++ + LD+L++A F+ G++ AL L+R L P
Sbjct: 185 TVLWMEQVLKQLDA--GEEATTTKSQV---LDYLSYAVFQLGDLHRALELTRRLLSLDPS 239
Query: 260 NKRMARNVLKYERLLAESPNHVVA----------EAVIQRPNIPHLQTRDTYEGLCQTLG 309
++R N+ +E+LL E + E + +RP + +L RD YE LC+ G
Sbjct: 240 HERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERP-VDYLPERDVYESLCRGEG 298
Query: 310 SQPTLYQIPSLYCSYETNSNA-YLLLQPIRKEVIHLEPYIALYHDFVSDSEAQKIRELAE 368
+ T + L+C Y + A LL+ P ++E P+I Y+D +SD E ++I+E+A+
Sbjct: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358
Query: 369 PWLQRSVVASGEKQLQV--EYRISKSAWLKDTVDPKLVTLNHRIAALTGLDVRPPYAEYL 426
P L R+ V + + YR+SKS+WL++ DP + +N R+ +TGL V+ AE L
Sbjct: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKT--AELL 416
Query: 427 QVVNYGIGGHYEPHFDHATSPSSPLYRMKSGNRVATFMIYLSSVEAGGATAFIYANLSVP 486
QV NYG+GG YEPHFD + P + + GNR+ATF+ Y+S VEAGGAT F ++
Sbjct: 417 QVANYGVGGQYEPHFDFSRRPFDSGLKTE-GNRLATFLNYMSDVEAGGATVFPDLGAAIW 475
Query: 487 VVRNAALFWWNLHRSGEGDSDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCSSSPED 544
+ A+FW+NL RSGEGD T HA CPVLVG KWV+NKW HE GQEF RPC S+ D
Sbjct: 476 PKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533
>gi|63252886 prolyl 4-hydroxylase, alpha I subunit isoform 1
precursor [Homo sapiens]
Length = 534
Score = 324 bits (830), Expect = 1e-88
Identities = 201/551 (36%), Positives = 309/551 (56%), Gaps = 46/551 (8%)
Query: 13 VLALGTGDPERAAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKV 72
+L +G P+ A G F+++ + + E+ L+ L+ Y++ EE +L + ++ +K+
Sbjct: 5 ILIIGILLPQSLAHPG-FFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEKL 63
Query: 73 LSLHEDSTTP----VANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGYEK----VE 124
L +T V +P+ AF L+KRL ++W + + + ++ + DG+
Sbjct: 64 DRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLV-----LKDMSDGFISNLTIQR 118
Query: 125 QDLPAFEDLEGAARALMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLTGDDC 184
Q P ED GAA+AL+RLQD Y L+ +++G +L K LT +DC
Sbjct: 119 QYFPNDEDQVGAAKALLRLQDTYNLDTDTISKG-----------NLPGVKHKSFLTAEDC 167
Query: 185 FQVGKVAYDMGDYYHAIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRAGNVS 244
F++GKVAY DYYH W+E+A+ GE T D+ S+ LD+L++A ++ G++
Sbjct: 168 FELGKVAYTEADYYHTELWMEQALRQL--DEGEISTIDKVSV---LDYLSYAVYQQGDLD 222
Query: 245 CALSLSREFLLYSPDNKRMARNVLKYERLLAESP--NHVVAEAVIQRPNIP--------H 294
AL L+++ L P+++R N+ +E ++A+ N ++ + P +
Sbjct: 223 KALLLTKKLLELDPEHQRANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDY 282
Query: 295 LQTRDTYEGLCQTLGSQPTLYQIPSLYCSY-ETNSNAYLLLQPIRKEVIHLEPYIALYHD 353
L R YE LC+ G + T + L+C Y + N N +L P ++E +P I +HD
Sbjct: 283 LPERQKYEMLCRGEGIKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHD 342
Query: 354 FVSDSEAQKIRELAEPWLQRSVVASGE--KQLQVEYRISKSAWLKDTVDPKLVTLNHRIA 411
+SD+E + +++LA+P L R+ V E K +YR+SKSAWL +P + +N RI
Sbjct: 343 IISDAEIEIVKDLAKPRLSRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQ 402
Query: 412 ALTGLDVRPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYR-MKSGNRVATFMIYLSSV 470
LTGLDV AE LQV NYG+GG YEPHFD A ++ + +GNR+AT++ Y+S V
Sbjct: 403 DLTGLDVST--AEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDV 460
Query: 471 EAGGATAFIYANLSVPVVRNAALFWWNLHRSGEGDSDTLHAGCPVLVGDKWVANKWIHEY 530
AGGAT F SV + A+FW+NL SGEGD T HA CPVLVG+KWV+NKW+HE
Sbjct: 461 SAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHER 520
Query: 531 GQEFRRPCSSS 541
GQEFRRPC+ S
Sbjct: 521 GQEFRRPCTLS 531
>gi|217272849 prolyl 4-hydroxylase, alpha I subunit isoform 2
precursor [Homo sapiens]
Length = 534
Score = 323 bits (827), Expect = 3e-88
Identities = 201/552 (36%), Positives = 313/552 (56%), Gaps = 48/552 (8%)
Query: 13 VLALGTGDPERAAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKV 72
+L +G P+ A G F+++ + + E+ L+ L+ Y++ EE +L + ++ +K+
Sbjct: 5 ILIIGILLPQSLAHPG-FFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEKL 63
Query: 73 LSLHEDSTTP----VANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGYEK----VE 124
L +T V +P+ AF L+KRL ++W + + + ++ + DG+
Sbjct: 64 DRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLV-----LKDMSDGFISNLTIQR 118
Query: 125 QDLPAFEDLEGAARALMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLTGDDC 184
Q P ED GAA+AL+RLQD Y L+ +++G +L K LT +DC
Sbjct: 119 QYFPNDEDQVGAAKALLRLQDTYNLDTDTISKG-----------NLPGVKHKSFLTAEDC 167
Query: 185 FQVGKVAYDMGDYYHAIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRAGNVS 244
F++GKVAY DYYH W+E+A+ GE T D+ S+ LD+L++A ++ G++
Sbjct: 168 FELGKVAYTEADYYHTELWMEQALRQL--DEGEISTIDKVSV---LDYLSYAVYQQGDLD 222
Query: 245 CALSLSREFLLYSPDNKRMARNVLKYERLLAESP--NHVVAEAVIQRPNIP--------H 294
AL L+++ L P+++R N+ +E ++A+ N ++ + P +
Sbjct: 223 KALLLTKKLLELDPEHQRANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDY 282
Query: 295 LQTRDTYEGLCQTLGSQPTLYQIPSLYCSY-ETNSNAYLLLQPIRKEVIHLEPYIALYHD 353
L R YE LC+ G + T + L+C Y + N N +L P ++E +P I +HD
Sbjct: 283 LPERQKYEMLCRGEGIKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHD 342
Query: 354 FVSDSEAQKIRELAEPWLQRSVVAS---GEKQLQVEYRISKSAWLKDTVDPKLVTLNHRI 410
+SD+E + +++LA+P L+R+ +++ G+ + V YRISKSAWL +P + +N RI
Sbjct: 343 IISDAEIEIVKDLAKPRLRRATISNPITGDLET-VHYRISKSAWLSGYENPVVSRINMRI 401
Query: 411 AALTGLDVRPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYR-MKSGNRVATFMIYLSS 469
LTGLDV AE LQV NYG+GG YEPHFD A ++ + +GNR+AT++ Y+S
Sbjct: 402 QDLTGLDVST--AEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSD 459
Query: 470 VEAGGATAFIYANLSVPVVRNAALFWWNLHRSGEGDSDTLHAGCPVLVGDKWVANKWIHE 529
V AGGAT F SV + A+FW+NL SGEGD T HA CPVLVG+KWV+NKW+HE
Sbjct: 460 VSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHE 519
Query: 530 YGQEFRRPCSSS 541
GQEFRRPC+ S
Sbjct: 520 RGQEFRRPCTLS 531
>gi|63252888 prolyl 4-hydroxylase, alpha I subunit isoform 2
precursor [Homo sapiens]
Length = 534
Score = 323 bits (827), Expect = 3e-88
Identities = 201/552 (36%), Positives = 313/552 (56%), Gaps = 48/552 (8%)
Query: 13 VLALGTGDPERAAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKV 72
+L +G P+ A G F+++ + + E+ L+ L+ Y++ EE +L + ++ +K+
Sbjct: 5 ILIIGILLPQSLAHPG-FFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEKL 63
Query: 73 LSLHEDSTTP----VANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGYEK----VE 124
L +T V +P+ AF L+KRL ++W + + + ++ + DG+
Sbjct: 64 DRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLV-----LKDMSDGFISNLTIQR 118
Query: 125 QDLPAFEDLEGAARALMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLTGDDC 184
Q P ED GAA+AL+RLQD Y L+ +++G +L K LT +DC
Sbjct: 119 QYFPNDEDQVGAAKALLRLQDTYNLDTDTISKG-----------NLPGVKHKSFLTAEDC 167
Query: 185 FQVGKVAYDMGDYYHAIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRAGNVS 244
F++GKVAY DYYH W+E+A+ GE T D+ S+ LD+L++A ++ G++
Sbjct: 168 FELGKVAYTEADYYHTELWMEQALRQL--DEGEISTIDKVSV---LDYLSYAVYQQGDLD 222
Query: 245 CALSLSREFLLYSPDNKRMARNVLKYERLLAESP--NHVVAEAVIQRPNIP--------H 294
AL L+++ L P+++R N+ +E ++A+ N ++ + P +
Sbjct: 223 KALLLTKKLLELDPEHQRANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDY 282
Query: 295 LQTRDTYEGLCQTLGSQPTLYQIPSLYCSY-ETNSNAYLLLQPIRKEVIHLEPYIALYHD 353
L R YE LC+ G + T + L+C Y + N N +L P ++E +P I +HD
Sbjct: 283 LPERQKYEMLCRGEGIKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHD 342
Query: 354 FVSDSEAQKIRELAEPWLQRSVVAS---GEKQLQVEYRISKSAWLKDTVDPKLVTLNHRI 410
+SD+E + +++LA+P L+R+ +++ G+ + V YRISKSAWL +P + +N RI
Sbjct: 343 IISDAEIEIVKDLAKPRLRRATISNPITGDLET-VHYRISKSAWLSGYENPVVSRINMRI 401
Query: 411 AALTGLDVRPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYR-MKSGNRVATFMIYLSS 469
LTGLDV AE LQV NYG+GG YEPHFD A ++ + +GNR+AT++ Y+S
Sbjct: 402 QDLTGLDVST--AEELQVANYGVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSD 459
Query: 470 VEAGGATAFIYANLSVPVVRNAALFWWNLHRSGEGDSDTLHAGCPVLVGDKWVANKWIHE 529
V AGGAT F SV + A+FW+NL SGEGD T HA CPVLVG+KWV+NKW+HE
Sbjct: 460 VSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHE 519
Query: 530 YGQEFRRPCSSS 541
GQEFRRPC+ S
Sbjct: 520 RGQEFRRPCTLS 531
>gi|217272851 prolyl 4-hydroxylase, alpha I subunit isoform 3
precursor [Homo sapiens]
Length = 516
Score = 285 bits (728), Expect = 1e-76
Identities = 188/550 (34%), Positives = 293/550 (53%), Gaps = 62/550 (11%)
Query: 13 VLALGTGDPERAAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKV 72
+L +G P+ A G F+++ + + E+ L+ L+ Y++ EE +L + ++ +K+
Sbjct: 5 ILIIGILLPQSLAHPG-FFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEKL 63
Query: 73 LSLHEDSTTP----VANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGYEK----VE 124
L +T V +P+ AF L+KRL ++W + + + ++ + DG+
Sbjct: 64 DRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLV-----LKDMSDGFISNLTIQR 118
Query: 125 QDLPAFEDLEGAARALMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLTGDDC 184
Q P ED GAA+AL+RLQD Y L+ +++G +L K LT +DC
Sbjct: 119 QYFPNDEDQVGAAKALLRLQDTYNLDTDTISKG-----------NLPGVKHKSFLTAEDC 167
Query: 185 FQVGKVAYDMGDYYHAIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRAGNVS 244
F++GKVAY DYYH W+E+A+ GE T D+ S+ LD+L++A ++ G++
Sbjct: 168 FELGKVAYTEADYYHTELWMEQALRQL--DEGEISTIDKVSV---LDYLSYAVYQQGDLD 222
Query: 245 CALSLSREFLLYSPDNKRMARNVLKYERLLAESP--NHVVAEAVIQRPNIP--------H 294
AL L+++ L P+++R N+ +E ++A+ N ++ + P +
Sbjct: 223 KALLLTKKLLELDPEHQRANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDY 282
Query: 295 LQTRDTYEGLCQTLGSQPTLYQIPSLYCSY-ETNSNAYLLLQPIRKEVIHLEPYIALYHD 353
L R YE LC+ G + T + L+C Y + N N +L P ++E +P I +HD
Sbjct: 283 LPERQKYEMLCRGEGIKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHD 342
Query: 354 FVSDSEAQKIRELAEPWLQRSVVASGE--KQLQVEYRISKSAWLKDTVDPKLVTLNHRIA 411
+SD+E + +++LA+P L R+ V E K +YR+SKSAWL +P + +N RI
Sbjct: 343 IISDAEIEIVKDLAKPRLSRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQ 402
Query: 412 ALTGLDVRPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYRMKSGNRVATFMIYLSSVE 471
LTGLDV AE LQ + +GNR+AT++ Y+S V
Sbjct: 403 DLTGLDVST--AEELQ-----------------KDEPDAFKELGTGNRIATWLFYMSDVS 443
Query: 472 AGGATAFIYANLSVPVVRNAALFWWNLHRSGEGDSDTLHAGCPVLVGDKWVANKWIHEYG 531
AGGAT F SV + A+FW+NL SGEGD T HA CPVLVG+KWV+NKW+HE G
Sbjct: 444 AGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERG 503
Query: 532 QEFRRPCSSS 541
QEFRRPC+ S
Sbjct: 504 QEFRRPCTLS 513
>gi|29570771 hypoxia-inducible factor prolyl 4-hydroxylase isoform a
[Homo sapiens]
Length = 502
Score = 67.8 bits (164), Expect = 2e-11
Identities = 50/167 (29%), Positives = 67/167 (40%), Gaps = 44/167 (26%)
Query: 406 LNHRIAALTGLDVR-PPYAEYLQVVNYGIGGHYEPHFD-----------HATSPSSPLYR 453
+ R+ LT L +E LQVV YG GGHY H D H ++
Sbjct: 293 IRQRVLRLTRLSPEIVELSEPLQVVRYGEGGHYHAHVDSGPVYPETICSHTKLVANESVP 352
Query: 454 MKSGNRVATFMIYLSSVEAGGATAFIYA---------------------------NLSVP 486
++ R T + YL++V GG T F A NL V
Sbjct: 353 FETSCRYMTVLFYLNNVTGGGETVFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVK 412
Query: 487 VVRNAALFWWNLHRSGEG-----DSDTLHAGCPVLVGDKWVANKWIH 528
+ A+FW+N G+G D +LH GC V G KW+AN WI+
Sbjct: 413 PQQGTAVFWYNYLPDGQGWVGDVDDYSLHGGCLVTRGTKWIANNWIN 459
>gi|64085083 hypoxia-inducible factor prolyl 4-hydroxylase isoform c
[Homo sapiens]
Length = 563
Score = 49.7 bits (117), Expect = 7e-06
Identities = 37/127 (29%), Positives = 48/127 (37%), Gaps = 40/127 (31%)
Query: 442 DHATSPSSPLYRMKSGN--------RVATFMIYLSSVEAGGATAFIYA------------ 481
DH P SP + G T + YL++V GG T F A
Sbjct: 394 DHWVIPVSPWEHPQLGTCSVPPLPYSYMTVLFYLNNVTGGGETVFPVADNRTYDEMSLIQ 453
Query: 482 ---------------NLSVPVVRNAALFWWNLHRSGEG-----DSDTLHAGCPVLVGDKW 521
NL V + A+FW+N G+G D +LH GC V G KW
Sbjct: 454 DDVDLRDTRRHCDKGNLRVKPQQGTAVFWYNYLPDGQGWVGDVDDYSLHGGCLVTRGTKW 513
Query: 522 VANKWIH 528
+AN WI+
Sbjct: 514 IANNWIN 520
Score = 32.7 bits (73), Expect = 0.87
Identities = 20/48 (41%), Positives = 24/48 (50%), Gaps = 6/48 (12%)
Query: 406 LNHRIAALTGLDVR-PPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLY 452
+ R+ LT L +E LQVV YG GGHY H D S P+Y
Sbjct: 293 IRQRVLRLTRLSPEIVELSEPLQVVRYGEGGHYHAHVD-----SGPVY 335
>gi|5453601 cartilage associated protein precursor [Homo sapiens]
Length = 401
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/75 (29%), Positives = 38/75 (50%)
Query: 199 HAIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRAGNVSCALSLSREFLLYSP 258
H + ++ + FR S + + + L FAYF+A N+ A++ + FLL P
Sbjct: 117 HCLKRCKQGLPAFRQSQPSREVLADFQRREPYKFLQFAYFKANNLPKAIAAAHTFLLKHP 176
Query: 259 DNKRMARNVLKYERL 273
D++ M RN+ Y+ L
Sbjct: 177 DDEMMKRNMAYYKSL 191
>gi|197313662 leprecan-like 1 isoform b [Homo sapiens]
Length = 527
Score = 40.4 bits (93), Expect = 0.004
Identities = 22/55 (40%), Positives = 32/55 (58%)
Query: 231 DHLAFAYFRAGNVSCALSLSREFLLYSPDNKRMARNVLKYERLLAESPNHVVAEA 285
D+L FAY+R G AL ++ +LL PD++ + NV YE LL +S + EA
Sbjct: 129 DYLQFAYYRVGEYVKALECAKAYLLCHPDDEDVLDNVDYYESLLDDSIDPASIEA 183
>gi|27764882 leprecan-like 1 isoform a [Homo sapiens]
Length = 708
Score = 40.4 bits (93), Expect = 0.004
Identities = 22/55 (40%), Positives = 32/55 (58%)
Query: 231 DHLAFAYFRAGNVSCALSLSREFLLYSPDNKRMARNVLKYERLLAESPNHVVAEA 285
D+L FAY+R G AL ++ +LL PD++ + NV YE LL +S + EA
Sbjct: 310 DYLQFAYYRVGEYVKALECAKAYLLCHPDDEDVLDNVDYYESLLDDSIDPASIEA 364
>gi|186928835 leprecan 1 isoform 1 [Homo sapiens]
Length = 736
Score = 37.0 bits (84), Expect = 0.046
Identities = 17/54 (31%), Positives = 32/54 (59%)
Query: 223 EASLEDALDHLAFAYFRAGNVSCALSLSREFLLYSPDNKRMARNVLKYERLLAE 276
E L ++L FAY+ GN + A+ ++ +LL+ P+++ M +N+ Y +L E
Sbjct: 297 EDFLPSHYNYLQFAYYNIGNYTQAVECAKTYLLFFPNDEVMNQNLAYYAAMLGE 350
>gi|226371643 leprecan 1 isoform 2 [Homo sapiens]
Length = 697
Score = 37.0 bits (84), Expect = 0.046
Identities = 17/54 (31%), Positives = 32/54 (59%)
Query: 223 EASLEDALDHLAFAYFRAGNVSCALSLSREFLLYSPDNKRMARNVLKYERLLAE 276
E L ++L FAY+ GN + A+ ++ +LL+ P+++ M +N+ Y +L E
Sbjct: 297 EDFLPSHYNYLQFAYYNIGNYTQAVECAKTYLLFFPNDEVMNQNLAYYAAMLGE 350
>gi|18921093 transient receptor potential cation channel, subfamily M,
member 6 [Homo sapiens]
Length = 2022
Score = 30.8 bits (68), Expect = 3.3
Identities = 22/57 (38%), Positives = 27/57 (47%), Gaps = 3/57 (5%)
Query: 72 VLSLHEDSTTPVANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGYEKVEQDLP 128
VL+ +D T V L T + SDW +V E E I L DG +K EQ LP
Sbjct: 1372 VLATEQDIQTEVLVHLTGQTPVV---SDWASVDEPKEKHEPIAHLLDGQDKAEQVLP 1425
>gi|17402888 neuronal pentraxin receptor [Homo sapiens]
Length = 500
Score = 30.8 bits (68), Expect = 3.3
Identities = 14/37 (37%), Positives = 23/37 (62%)
Query: 100 WRNVVHSLEASENIRALKDGYEKVEQDLPAFEDLEGA 136
W + LE + +RAL+D +++EQ+LPA +L A
Sbjct: 184 WDSPALILELEDAVRALRDRIDRLEQELPARVNLSAA 220
>gi|125628636 keratin 80 isoform a [Homo sapiens]
Length = 452
Score = 30.4 bits (67), Expect = 4.3
Identities = 17/60 (28%), Positives = 30/60 (50%)
Query: 12 AVLALGTGDPERAAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDK 71
AV L + E A D F++L +AL +LL +L+G+++ + DL Y++
Sbjct: 75 AVQQLKNQEKEEMKALNDKFASLIGKVQALEQRNQLLETRWSFLQGQDSAIFDLGHLYEE 134
>gi|125628632 keratin 80 isoform b [Homo sapiens]
Length = 422
Score = 30.4 bits (67), Expect = 4.3
Identities = 17/60 (28%), Positives = 30/60 (50%)
Query: 12 AVLALGTGDPERAAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDK 71
AV L + E A D F++L +AL +LL +L+G+++ + DL Y++
Sbjct: 75 AVQQLKNQEKEEMKALNDKFASLIGKVQALEQRNQLLETRWSFLQGQDSAIFDLGHLYEE 134
>gi|31317256 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 29.6 bits (65), Expect = 7.4
Identities = 30/106 (28%), Positives = 41/106 (38%), Gaps = 19/106 (17%)
Query: 177 FSLTGDDCFQVGKVAYDMGDYYHAIPWLEEAVSLFRGS------YGEWKTEDEASLEDAL 230
F TGD Q K Y + D A+ W+EE V F G +G SL L
Sbjct: 210 FLSTGD---QAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLL-TL 265
Query: 231 DHLAFAYFRAGNVSCALSLSREFLLYSPDNKRMARNVLKYERLLAE 276
H + F+ + +LS + Y P KY R+LA+
Sbjct: 266 SHYSEGLFQKAIIQSGTALSSWAVNYQP---------AKYTRILAD 302
>gi|24308209 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 29.6 bits (65), Expect = 7.4
Identities = 30/106 (28%), Positives = 41/106 (38%), Gaps = 19/106 (17%)
Query: 177 FSLTGDDCFQVGKVAYDMGDYYHAIPWLEEAVSLFRGS------YGEWKTEDEASLEDAL 230
F TGD Q K Y + D A+ W+EE V F G +G SL L
Sbjct: 210 FLSTGD---QAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLL-TL 265
Query: 231 DHLAFAYFRAGNVSCALSLSREFLLYSPDNKRMARNVLKYERLLAE 276
H + F+ + +LS + Y P KY R+LA+
Sbjct: 266 SHYSEGLFQKAIIQSGTALSSWAVNYQP---------AKYTRILAD 302
>gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens]
Length = 1012
Score = 29.6 bits (65), Expect = 7.4
Identities = 28/115 (24%), Positives = 49/115 (42%), Gaps = 19/115 (16%)
Query: 20 DPERAAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKVLSLHEDS 79
D ++ A D +S+ T ER + L RR E+ + F ++ L
Sbjct: 389 DMKKLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHF---IILLSNKD 445
Query: 80 TTPVANPLLAFTLIKRLQSDWRNVVHSLE---------ASENIRALKDGYEKVEQ 125
T +A L+++L WRN+V+ L+ SE ++ +KDG K ++
Sbjct: 446 TEDLA-------LLQKLTQKWRNLVNKLKQEVEQMEESTSETLKIVKDGLIKWQE 493
>gi|51093834 hypothetical protein LOC126859 isoform 2 [Homo sapiens]
Length = 938
Score = 29.6 bits (65), Expect = 7.4
Identities = 28/115 (24%), Positives = 49/115 (42%), Gaps = 19/115 (16%)
Query: 20 DPERAAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKVLSLHEDS 79
D ++ A D +S+ T ER + L RR E+ + F ++ L
Sbjct: 389 DMKKLVAERDIWSSATYELALKVIERNRVILARRLYLNEKGWNKYTKHF---IILLSNKD 445
Query: 80 TTPVANPLLAFTLIKRLQSDWRNVVHSLE---------ASENIRALKDGYEKVEQ 125
T +A L+++L WRN+V+ L+ SE ++ +KDG K ++
Sbjct: 446 TEDLA-------LLQKLTQKWRNLVNKLKQEVEQMEESTSETLKIVKDGLIKWQE 493
>gi|7705433 eukaryotic translation initiation factor 3 subunit 6
interacting protein [Homo sapiens]
Length = 564
Score = 29.6 bits (65), Expect = 7.4
Identities = 51/207 (24%), Positives = 79/207 (38%), Gaps = 36/207 (17%)
Query: 194 MGDYYHAIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRAGNVSCALSLSREF 253
+GDYY AI LE + L + S E + + ++ FAY A+ +
Sbjct: 284 LGDYYQAIKVLEN-IELNKKSMYSRVPECQVT---TYYYVGFAYLMMRRYQDAIRVFANI 339
Query: 254 LLYSPDNKRM-ARNVLKYERL--LAESPNHVVAEAVIQRP----NIPHLQTRDTY-EGLC 305
LLY K M R KYE + E + ++A A+ P HLQ R+ Y + +
Sbjct: 340 LLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKML 399
Query: 306 QTLGSQPTLYQIPSLYCSYETNSNAYLLLQPIRKEVIHLEPYIALYHDFVSDSEAQKIRE 365
+ P +Y+ Y + L P+ ++ P YH
Sbjct: 400 RMQKGDPQVYEELFSY-------SCPKFLSPVVPNYDNVHPN---YH------------- 436
Query: 366 LAEPWLQRSVVASGEKQLQVEYRISKS 392
EP+LQ+ V S E Q Q + +S
Sbjct: 437 -KEPFLQQLKVFSDEVQQQAQLSTIRS 462
>gi|40538788 neuroligin 4, Y-linked [Homo sapiens]
Length = 816
Score = 29.6 bits (65), Expect = 7.4
Identities = 30/106 (28%), Positives = 41/106 (38%), Gaps = 19/106 (17%)
Query: 177 FSLTGDDCFQVGKVAYDMGDYYHAIPWLEEAVSLFRGS------YGEWKTEDEASLEDAL 230
F TGD Q K Y + D A+ W+EE V F G +G SL L
Sbjct: 210 FLSTGD---QAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLL-TL 265
Query: 231 DHLAFAYFRAGNVSCALSLSREFLLYSPDNKRMARNVLKYERLLAE 276
H + F+ + +LS + Y P KY R+LA+
Sbjct: 266 SHYSEGLFQKAIIQSGTALSSWAVNYQP---------AKYTRILAD 302
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 29.6 bits (65), Expect = 7.4
Identities = 12/37 (32%), Positives = 22/37 (59%), Gaps = 1/37 (2%)
Query: 183 DCF-QVGKVAYDMGDYYHAIPWLEEAVSLFRGSYGEW 218
DC+ ++G +A D G++Y A W +EA+ + + W
Sbjct: 532 DCYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAW 568
>gi|115387118 hypothetical protein LOC57562 [Homo sapiens]
Length = 1117
Score = 29.6 bits (65), Expect = 7.4
Identities = 19/66 (28%), Positives = 34/66 (51%), Gaps = 12/66 (18%)
Query: 79 STTPVANPLLAFTLIKRLQSDWRNVVH-----SLEASENIRALKDGYEKV-------EQD 126
S PVA PL+ + I+ + +N +H +++ S+ + LKDG E+ +++
Sbjct: 455 SCVPVATPLVLPSNIQSARPSAKNSIHIKEIDAVQCSDKLDELKDGKEEEIKYFNCNKEE 514
Query: 127 LPAFED 132
LP F D
Sbjct: 515 LPLFSD 520
>gi|37537710 La ribonucleoprotein domain family, member 6 isoform 1
[Homo sapiens]
Length = 491
Score = 29.3 bits (64), Expect = 9.6
Identities = 18/64 (28%), Positives = 33/64 (51%), Gaps = 4/64 (6%)
Query: 87 LLAFTLIKRLQSDWRNVVHSLEASENIRALKDGYEKVEQ--DLPAFEDLEGAARALMRLQ 144
L +F +K L DWR H+L+ S + L + + KV + +P F + E ++ +
Sbjct: 132 LTSFKKVKHLTRDWRTTAHALKYSV-VLELNEDHRKVRRTTPVPLFPN-ENLPSKMLLVY 189
Query: 145 DVYM 148
D+Y+
Sbjct: 190 DLYL 193
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,739,303
Number of Sequences: 37866
Number of extensions: 902320
Number of successful extensions: 2180
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2087
Number of HSP's gapped (non-prelim): 36
length of query: 544
length of database: 18,247,518
effective HSP length: 107
effective length of query: 437
effective length of database: 14,195,856
effective search space: 6203589072
effective search space used: 6203589072
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.