Guide to the Human Genome
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Search of human proteins with 33469968

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33469968 minichromosome maintenance complex component 7
isoform 1 [Homo sapiens]
         (719 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33469968 minichromosome maintenance complex component 7 isofo...  1412   0.0  
gi|33469922 minichromosome maintenance complex component 7 isofo...  1067   0.0  
gi|33469919 minichromosome maintenance complex component 4 [Homo...   333   3e-91
gi|33469917 minichromosome maintenance complex component 4 [Homo...   333   3e-91
gi|7427519 minichromosome maintenance complex component 6 [Homo ...   319   5e-87
gi|6631095 minichromosome maintenance complex component 3 [Homo ...   318   1e-86
gi|33356547 minichromosome maintenance complex component 2 [Homo...   317   2e-86
gi|23510448 minichromosome maintenance complex component 5 [Homo...   310   4e-84
gi|19923727 minichromosome maintenance complex component 8 isofo...   262   9e-70
gi|33469924 minichromosome maintenance complex component 8 isofo...   255   9e-68
gi|23397546 minichromosome maintenance complex component 9 [Homo...   116   8e-26
gi|31543667 suppressor of var1, 3-like 1 [Homo sapiens]                33   1.2  
gi|193082991 GTP binding protein 3 (mitochondrial) isoform V [Ho...    32   1.6  
gi|193082988 GTP binding protein 3 (mitochondrial) isoform IV [H...    32   1.6  
gi|92091575 coiled-coil domain containing 57 [Homo sapiens]            32   2.1  
gi|58761544 amine oxidase (flavin containing) domain 2 isoform a...    32   2.7  
gi|58761546 amine oxidase (flavin containing) domain 2 isoform b...    32   2.7  
gi|32698692 zinc finger, DHHC domain containing 8 [Homo sapiens]       31   4.6  
gi|21396489 mitochondrial lon peptidase 1 [Homo sapiens]               30   6.0  
gi|73623035 sperm associated antigen 5 [Homo sapiens]                  30   6.0  
gi|53729339 mitochondrial translational initiation factor 2 prec...    30   7.8  
gi|53729337 mitochondrial translational initiation factor 2 prec...    30   7.8  
gi|4506221 proteasome 26S non-ATPase subunit 12 isoform 1 [Homo ...    30   7.8  
gi|28872765 proteasome 26S non-ATPase subunit 12 isoform 2 [Homo...    30   7.8  

>gi|33469968 minichromosome maintenance complex component 7 isoform
           1 [Homo sapiens]
          Length = 719

 Score = 1412 bits (3656), Expect = 0.0
 Identities = 719/719 (100%), Positives = 719/719 (100%)

Query: 1   MALKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVALYVDLDDVAEDDP 60
           MALKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVALYVDLDDVAEDDP
Sbjct: 1   MALKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVALYVDLDDVAEDDP 60

Query: 61  ELVDSICENARRYAKLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGMVR 120
           ELVDSICENARRYAKLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGMVR
Sbjct: 61  ELVDSICENARRYAKLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGMVR 120

Query: 121 SPQNQYPAELMRRFELYFQGPSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVA 180
           SPQNQYPAELMRRFELYFQGPSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVA
Sbjct: 121 SPQNQYPAELMRRFELYFQGPSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVA 180

Query: 181 TYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEH 240
           TYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEH
Sbjct: 181 TYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEH 240

Query: 241 SDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEA 300
           SDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEA
Sbjct: 241 SDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEA 300

Query: 301 HRIVKMNKSEDDESGAGELTREELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVG 360
           HRIVKMNKSEDDESGAGELTREELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVG
Sbjct: 301 HRIVKMNKSEDDESGAGELTREELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLLLLVG 360

Query: 361 GVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLR 420
           GVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLR
Sbjct: 361 GVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLR 420

Query: 421 DSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNA 480
           DSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNA
Sbjct: 421 DSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNA 480

Query: 481 RCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYV 540
           RCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYV
Sbjct: 481 RCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYV 540

Query: 541 HQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASKDATY 600
           HQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASKDATY
Sbjct: 541 HQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASKDATY 600

Query: 601 TSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADV 660
           TSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADV
Sbjct: 601 TSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADV 660

Query: 661 IFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRITFV 719
           IFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRITFV
Sbjct: 661 IFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRITFV 719


>gi|33469922 minichromosome maintenance complex component 7 isoform
           2 [Homo sapiens]
          Length = 543

 Score = 1067 bits (2760), Expect = 0.0
 Identities = 543/543 (100%), Positives = 543/543 (100%)

Query: 177 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMK 236
           MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMK
Sbjct: 1   MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMK 60

Query: 237 MQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSET 296
           MQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSET
Sbjct: 61  MQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSET 120

Query: 297 YLEAHRIVKMNKSEDDESGAGELTREELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLL 356
           YLEAHRIVKMNKSEDDESGAGELTREELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLL
Sbjct: 121 YLEAHRIVKMNKSEDDESGAGELTREELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLL 180

Query: 357 LLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTA 416
           LLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTA
Sbjct: 181 LLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTA 240

Query: 417 AVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILT 476
           AVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILT
Sbjct: 241 AVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILT 300

Query: 477 TLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQH 536
           TLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQH
Sbjct: 301 TLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQH 360

Query: 537 ITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASK 596
           ITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASK
Sbjct: 361 ITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASK 420

Query: 597 DATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQR 656
           DATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQR
Sbjct: 421 DATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQR 480

Query: 657 PADVIFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRI 716
           PADVIFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRI
Sbjct: 481 PADVIFATVRELVSGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRI 540

Query: 717 TFV 719
           TFV
Sbjct: 541 TFV 543


>gi|33469919 minichromosome maintenance complex component 4 [Homo
           sapiens]
          Length = 863

 Score =  333 bits (854), Expect = 3e-91
 Identities = 232/666 (34%), Positives = 350/666 (52%), Gaps = 53/666 (7%)

Query: 68  ENARRYAKLFADAVQE---------LLPQYKER----EVVNKDVLDVYIEHRLMMEQRSR 114
           EN +R+ + F D + +           P Y +R     V+ +  L+V  EH +    ++ 
Sbjct: 164 ENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGEPFLNVNCEH-IKSFDKNL 222

Query: 115 DPGMVRSPQNQYPAELMRRFELYFQGPSSN--------------KPRVIREVRADSVGKL 160
              ++  PQ   P   M   E++F     +              K + +R +  + + +L
Sbjct: 223 YRQLISYPQEVIPTFDMAVNEIFFDRYPDSILEHQIQVRPFNALKTKNMRNLNPEDIDQL 282

Query: 161 VTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRL 220
           +T+ G+V R S++ P+M  A + C  C   T   +         +C    C T  S   +
Sbjct: 283 ITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGRIAEPSVCG--RCHTTHSMALI 340

Query: 221 YLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPI 280
           + +   S F   Q +K+QE  + +P G  P ++ +    +     QPGD V+VTGI+  +
Sbjct: 341 HNR---SLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAV 397

Query: 281 -LRTGFRQVVQGLLSETYLEAHRIVKMNKSED---DESGAGELTREELRQIAEE-----D 331
            +R   R      + +T+++     K +       DE    +L  E+  ++ +E     D
Sbjct: 398 PIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSEKRVELLKELSRKPD 457

Query: 332 FYEKLAASIAPEIYGHEDVKKALLLLLVGGV--DQSPRGM-KIRGNINICLMGDPGVAKS 388
            YE+LA+++AP IY HED+KK +LL L GG   D S  G  K R  INI L GDPG +KS
Sbjct: 458 IYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKS 517

Query: 389 QLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFD 448
           QLL Y+  L PR QYT+G+GSS VGLTA V++D  + +L L+ GALVL+D G+CCIDEFD
Sbjct: 518 QLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFD 577

Query: 449 KMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLP 508
           KM E+ R+ +HEVMEQQT+SIAKAGI+  LNAR S+LAAANP   ++NP+++  +NIQLP
Sbjct: 578 KMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLP 637

Query: 509 AALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCRE 568
             LLSRFDL++L+ D  D   D RLA H+  ++  S +   + E LDM +++ YIA    
Sbjct: 638 HTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQAEE-ELLDMAVLKDYIAYAHS 696

Query: 569 K-QPMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEK 627
              P + E  +  +  AYV+MR+   +S+       R L +++RL+ A A++R+ + VE 
Sbjct: 697 TIMPRLSEEASQALIEAYVDMRK-IGSSRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEA 755

Query: 628 EDVNEAIRLMEMSKDSLLGDKGQTARTQRPADVIFATVRELVSGGRSVRFSEAEQRCV-S 686
            DV EA RL        L       RT      I  T     S  R    +EA ++ + S
Sbjct: 756 IDVEEAKRLHR----EALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALKKLILS 811

Query: 687 RGFTPA 692
           +G TPA
Sbjct: 812 KGKTPA 817


>gi|33469917 minichromosome maintenance complex component 4 [Homo
           sapiens]
          Length = 863

 Score =  333 bits (854), Expect = 3e-91
 Identities = 232/666 (34%), Positives = 350/666 (52%), Gaps = 53/666 (7%)

Query: 68  ENARRYAKLFADAVQE---------LLPQYKER----EVVNKDVLDVYIEHRLMMEQRSR 114
           EN +R+ + F D + +           P Y +R     V+ +  L+V  EH +    ++ 
Sbjct: 164 ENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGEPFLNVNCEH-IKSFDKNL 222

Query: 115 DPGMVRSPQNQYPAELMRRFELYFQGPSSN--------------KPRVIREVRADSVGKL 160
              ++  PQ   P   M   E++F     +              K + +R +  + + +L
Sbjct: 223 YRQLISYPQEVIPTFDMAVNEIFFDRYPDSILEHQIQVRPFNALKTKNMRNLNPEDIDQL 282

Query: 161 VTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRL 220
           +T+ G+V R S++ P+M  A + C  C   T   +         +C    C T  S   +
Sbjct: 283 ITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGRIAEPSVCG--RCHTTHSMALI 340

Query: 221 YLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPI 280
           + +   S F   Q +K+QE  + +P G  P ++ +    +     QPGD V+VTGI+  +
Sbjct: 341 HNR---SLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAV 397

Query: 281 -LRTGFRQVVQGLLSETYLEAHRIVKMNKSED---DESGAGELTREELRQIAEE-----D 331
            +R   R      + +T+++     K +       DE    +L  E+  ++ +E     D
Sbjct: 398 PIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSEKRVELLKELSRKPD 457

Query: 332 FYEKLAASIAPEIYGHEDVKKALLLLLVGGV--DQSPRGM-KIRGNINICLMGDPGVAKS 388
            YE+LA+++AP IY HED+KK +LL L GG   D S  G  K R  INI L GDPG +KS
Sbjct: 458 IYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKS 517

Query: 389 QLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFD 448
           QLL Y+  L PR QYT+G+GSS VGLTA V++D  + +L L+ GALVL+D G+CCIDEFD
Sbjct: 518 QLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFD 577

Query: 449 KMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLP 508
           KM E+ R+ +HEVMEQQT+SIAKAGI+  LNAR S+LAAANP   ++NP+++  +NIQLP
Sbjct: 578 KMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLP 637

Query: 509 AALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCRE 568
             LLSRFDL++L+ D  D   D RLA H+  ++  S +   + E LDM +++ YIA    
Sbjct: 638 HTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEEQAEE-ELLDMAVLKDYIAYAHS 696

Query: 569 K-QPMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEK 627
              P + E  +  +  AYV+MR+   +S+       R L +++RL+ A A++R+ + VE 
Sbjct: 697 TIMPRLSEEASQALIEAYVDMRK-IGSSRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEA 755

Query: 628 EDVNEAIRLMEMSKDSLLGDKGQTARTQRPADVIFATVRELVSGGRSVRFSEAEQRCV-S 686
            DV EA RL        L       RT      I  T     S  R    +EA ++ + S
Sbjct: 756 IDVEEAKRLHR----EALKQSATDPRTGIVDISILTTGMSATSRKRKEELAEALKKLILS 811

Query: 687 RGFTPA 692
           +G TPA
Sbjct: 812 KGKTPA 817


>gi|7427519 minichromosome maintenance complex component 6 [Homo
           sapiens]
          Length = 821

 Score =  319 bits (818), Expect = 5e-87
 Identities = 216/677 (31%), Positives = 339/677 (50%), Gaps = 92/677 (13%)

Query: 11  EKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVALYVDLDDVAEDDPELVDSICENA 70
           EK +K   +F ++ +    + KY      L   E+  L V   D+ + + +L  +I E  
Sbjct: 24  EKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTIQEEF 83

Query: 71  RRYAKLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGMVRSPQNQYPAEL 130
            R       A++  +   KE                                       L
Sbjct: 84  YRVYPYLCRALKTFVKDRKE-------------------------------------IPL 106

Query: 131 MRRFELYFQG-PSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGA 189
            + F + FQ  P+ +K   IRE+ +  +G L  + G V R   V P++V  T+ C  C  
Sbjct: 107 AKDFYVAFQDLPTRHK---IRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQT 163

Query: 190 ETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNI 249
                 Q   +    +C +  C   R   R  L T  SRF+ FQ++++QE   ++P G+I
Sbjct: 164 VIRDVEQQFKYTQPNICRNPVCANRR---RFLLDTNKSRFVDFQKVRIQETQAELPRGSI 220

Query: 250 PRSITVLVEGENTRIAQPGDHVSVTGIFLPI------------LRTGFR---------QV 288
           PRS+ V++  E    AQ GD    TG  + +              T  R         + 
Sbjct: 221 PRSLEVILRAEAVESAQAGDKCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDGYETEG 280

Query: 289 VQGLLSETYLE-AHRIVKM-----------------NKSEDDESGAGELTREELRQIAE- 329
           ++GL +    + ++R+V +                 ++ +  ES   ++T +E  ++ E 
Sbjct: 281 IRGLRALGVRDLSYRLVFLACCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKVFEM 340

Query: 330 ---EDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSP-RGMKIRGNINICLMGDPGV 385
              ++ Y  L  S+ P I+G+++VK+ +LL+L GGV ++   G  +RG+IN+C++GDP  
Sbjct: 341 SQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGDPST 400

Query: 386 AKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCID 445
           AKSQ L +++  +PR+ YT+G+ SS  GLTAAV+RD  S E  +E GAL+LAD GVCCID
Sbjct: 401 AKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVCCID 460

Query: 446 EFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNI 505
           EFDKM   D+ AIHE MEQQTISI KAG+  TLNAR SILAAANP  G Y+  +SL+QNI
Sbjct: 461 EFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPISGHYDRSKSLKQNI 520

Query: 506 QLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAM 565
            L A ++SRFDL +++ D  +   D  +A+ I  +H    +   +   LD   +RRY+  
Sbjct: 521 NLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHSRIEESIDRVYSLDD--IRRYLLF 578

Query: 566 CREKQPMVPESLADYITAAYVEMRRE--AWASKDATYTSARTLLAILRLSTALARLRMVD 623
            R+ +P + +   D+I   Y  +R+   +  +K +   + R L +++RLS A+AR+   D
Sbjct: 579 ARQFKPKISKESEDFIVEQYKHLRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMHCCD 638

Query: 624 VVEKEDVNEAIRLMEMS 640
            V+ + V EA RL+  S
Sbjct: 639 EVQPKHVKEAFRLLNKS 655


>gi|6631095 minichromosome maintenance complex component 3 [Homo
           sapiens]
          Length = 808

 Score =  318 bits (815), Expect = 1e-86
 Identities = 221/629 (35%), Positives = 333/629 (52%), Gaps = 75/629 (11%)

Query: 76  LFADAVQELLPQYKEREVVNKD------------VLDVYIEHRLMMEQRSRDPGMVRSPQ 123
           ++   V+EL+   + R +VN +            +L+   E  +  ++  +D   V S  
Sbjct: 31  IYQSKVRELISDNQYRLIVNVNDLRRKNEKRANRLLNNAFEELVAFQRALKD--FVASID 88

Query: 124 NQYPAELMRRFELYFQGPSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYT 183
             Y A+    F +  +G   +K    R + +  +  +V V GIVT+ S V+PK+V + + 
Sbjct: 89  ATY-AKQYEEFYVGLEGSFGSKHVSPRTLTSCFLSCVVCVEGIVTKCSLVRPKVVRSVHY 147

Query: 184 CDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSGGRLYLQTRG--SRFIKFQEMKMQEHS 241
           C        +     T   L+  PS      +      L+T    S +   Q + +QE  
Sbjct: 148 CPATKKTIERRYSDLT--TLVAFPSSSVYPTKDEENNPLETEYGLSVYKDHQTITIQEMP 205

Query: 242 DQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIF--LPILRTGFRQVVQGLLSETYLE 299
           ++ P G +PRS+ V+++ +    A+PGD V V G +  LP  + G+          T L 
Sbjct: 206 EKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGTYRCLPGKKGGYTSGT----FRTVLI 261

Query: 300 AHRIVKMNKSEDDESGAGELTR-EELRQIAEEDFYEKLAASIAPEIYGHEDVKKALLLLL 358
           A  + +M+K       A ++ + ++  +   +D +++LA S+AP I+GH+ VKKA+L LL
Sbjct: 262 ACNVKQMSKDAQPSFSAEDIAKIKKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLL 321

Query: 359 VGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAA 417
           +GGV++    G  IRG+INI L+GDP VAKSQLL Y+   APR+  TTGRGSSGVGLTAA
Sbjct: 322 LGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAA 381

Query: 418 VLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTT 477
           V  D  +GE  LE GA+VLAD+GV CIDEFDKM++ DRTAIHEVMEQ  ++IAKAGI   
Sbjct: 382 VTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHAR 441

Query: 478 LNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHI 537
           LNARCS+LAAANP YGRY+  ++  +NI L  +LLSRFDLL+++ D+ D + D  ++ H+
Sbjct: 442 LNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHV 501

Query: 538 TYVH------------------------------QHSRQPPSQFEPLDMKL--------- 558
             +H                              Q  +Q    +E  D  L         
Sbjct: 502 LRMHRYRAPGEQDGDAMPLGSAVDILATDDPNFSQEDQQDTQIYEKHDNLLHGTKKKKEK 561

Query: 559 ------MRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASKDATYTS---ARTLLAI 609
                 M++YI + +  +P++ +  A YI   Y  +R +   S D   TS   ARTL  +
Sbjct: 562 MVSAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTARTSPVTARTLETL 621

Query: 610 LRLSTALARLRMVDVVEKEDVNEAIRLME 638
           +RL+TA A+ RM   V+ +D  EA+ L++
Sbjct: 622 IRLATAHAKARMSKTVDLQDAEEAVELVQ 650


>gi|33356547 minichromosome maintenance complex component 2 [Homo
           sapiens]
          Length = 904

 Score =  317 bits (813), Expect = 2e-86
 Identities = 193/518 (37%), Positives = 299/518 (57%), Gaps = 42/518 (8%)

Query: 149 IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCG--AETYQPIQSPTFMPLIMC 206
           +R +R   + +L+   G+VT  + V P++ +  Y C++C      +   Q+    P   C
Sbjct: 294 LRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPG-SC 352

Query: 207 PSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQ 266
           P  ECQ   S G   +    + +  +Q +++QE   +V  G +PRS   ++  +     +
Sbjct: 353 P--ECQ---SAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCK 407

Query: 267 PGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELTREELRQ 326
           PGD + +TGI+               +  T + A+ + K    +D++   GELT E+++ 
Sbjct: 408 PGDEIELTGIYHNNYDGSLNTANGFPVFATVILANHVAK----KDNKVAVGELTDEDVKM 463

Query: 327 IA----EEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGM-KIRGNINICLMG 381
           I     ++   EK+ ASIAP IYGHED+K+ L L L GG  ++P G  K+RG+IN+ L G
Sbjct: 464 ITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCG 523

Query: 382 DPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGV 441
           DPG AKSQ L YI++++ R+ +TTG+G+S VGLTA V R  VS E TLE GALVLAD+GV
Sbjct: 524 DPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGV 583

Query: 442 CCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSL 501
           C IDEFDKM + DRT+IHE MEQQ+ISI+KAGI+T+L ARC+++AAANP  GRY+P  + 
Sbjct: 584 CLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTF 643

Query: 502 EQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQ----------- 550
            +N+ L   ++SRFD+L +++D  D   D  LA+ +  V  H R  PS            
Sbjct: 644 SENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFV--VGSHVRHHPSNKEEEGLANGSA 701

Query: 551 ----------FEPLDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDAT 599
                      EPL  +++++YI   +E+  P + +   D +   Y ++R+E+ A+    
Sbjct: 702 AEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSIP 761

Query: 600 YTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLM 637
            T  R + +++R++ A AR+ + D V ++DVN AIR+M
Sbjct: 762 IT-VRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVM 798


>gi|23510448 minichromosome maintenance complex component 5 [Homo
           sapiens]
          Length = 734

 Score =  310 bits (793), Expect = 4e-84
 Identities = 209/655 (31%), Positives = 348/655 (53%), Gaps = 63/655 (9%)

Query: 10  KEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVALYVDLDDVAEDDPELVDSICEN 69
           + + K+FL+++    +     FKY ++L R  +  +  + V+++D+A  D +L D + + 
Sbjct: 32  QRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEMEDLASFDEDLADYLYKQ 91

Query: 70  ARRYAKLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGMVRSPQNQYPAE 129
              + +L  +A +E+  +        ++VL    + ++M++                   
Sbjct: 92  PAEHLQLLEEAAKEVADEVTRPRPSGEEVLQ---DIQVMLK------------------- 129

Query: 130 LMRRFELYFQGPSSNKPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGA 189
                       S   P  IR +++D +  LV + GI+   S V+ K    +  C  C  
Sbjct: 130 ------------SDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRN 177

Query: 190 ETYQPIQSPTFMPLIMCPSQECQTNRSG------GRLYLQTRGSRFIKFQEMKMQEHSDQ 243
                   P      +   ++C T+++G         ++     + + FQ +K+QE  D 
Sbjct: 178 TLTNIAMRPGLEGYAL--PRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDA 235

Query: 244 VPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGF-----RQVVQGLLSETYL 298
           VP G +PR + +  +        PG+ V++ GI+  I + G      R  V   +  +Y+
Sbjct: 236 VPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIY-SIKKFGLTTSRGRDRVGVGIRSSYI 294

Query: 299 EAHRIVKMNKSEDDESGAGELT---REELRQIAE-EDFYEKLAASIAPEIYGHEDVKKAL 354
               I +++      S AG ++    EE R++A   + YE ++ SIAP I+G  D+KKA+
Sbjct: 295 RVLGI-QVDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAI 353

Query: 355 LLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVG 413
             LL GG  +  P G+  RG+IN+ ++GDPG AKSQLL ++++ +P   YT+G+GSS  G
Sbjct: 354 ACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAG 413

Query: 414 LTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAG 473
           LTA+V+RD  S    +EGGA+VLAD GV CIDEFDKM E DR AIHE MEQQTISIAKAG
Sbjct: 414 LTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAG 473

Query: 474 ILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRL 533
           I TTLN+RCS+LAAAN  +GR++  +  E NI     +LSRFD++++++D  + + D+ L
Sbjct: 474 ITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVML 532

Query: 534 AQHITYVHQHSRQPPSQFE-PLDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRRE 591
           A+H+  +H  +       E  +D+  ++++IA CR K  P +    A+ +   Y+ MR  
Sbjct: 533 AKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSG 592

Query: 592 A-WASKDATYTSA-----RTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 640
           A    +D+   S+     R L AI+R++ AL+++++     + DV EA+RL ++S
Sbjct: 593 ARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVS 647


>gi|19923727 minichromosome maintenance complex component 8 isoform
           1 [Homo sapiens]
          Length = 840

 Score =  262 bits (669), Expect = 9e-70
 Identities = 177/548 (32%), Positives = 278/548 (50%), Gaps = 63/548 (11%)

Query: 149 IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 208
           ++ VRA+  GK + +RG V RVS +KP      + C  CG     P+    +     CP 
Sbjct: 207 LKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKYSLPTKCPV 266

Query: 209 QECQTNRSGGRLYLQTRGSRF---IKFQEMKMQE--HSDQVPVGNIPRSITVLVEGENTR 263
             C+     GR +   R S     + +Q +K+QE    DQ   G IPR+I   +  +   
Sbjct: 267 PVCR-----GRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVD 321

Query: 264 IAQPGDHVSVTGIF-LPILRTGFRQVVQGLLSETYLEAHRIV----KMNKSEDDESGAGE 318
              PGD V++TGI  +     G R      +   Y+EA+ I     +  KS +D    G 
Sbjct: 322 SCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGM 381

Query: 319 LTREELRQI-------AEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQ---SPRG 368
           L    L+ +       AEE+ ++ +  S+ P I+GHE VK  L L L GG  +       
Sbjct: 382 LMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNR 441

Query: 369 MKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELT 428
           + IRG+ +I ++GDPG+ KSQ+L     +APR  Y  G  ++  GLT  + +DS SG+  
Sbjct: 442 IPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFA 501

Query: 429 LEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAA 488
           LE GALVL DQG+C IDEFDKM      A+ E MEQQ+IS+AKAG++ +L AR SI+AAA
Sbjct: 502 LEAGALVLGDQGICGIDEFDKMGN-QHQALLEAMEQQSISLAKAGVVCSLPARTSIIAAA 560

Query: 489 NPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQ-- 546
           NP  G YN  +++ +N+++ +ALLSRFDL++++ D P+  +D  L++H+  +    ++  
Sbjct: 561 NPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHVIAIRAGKQRTI 620

Query: 547 ---------------------------------PPSQFEPLDMKLMRRYIAMCRE-KQPM 572
                                            P    +P+  +L+R+YI   R+   P 
Sbjct: 621 SSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDPIPHQLLRKYIGYARQYVYPR 680

Query: 573 VPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNE 632
           +    A  +   Y+E+R+++     +  T+ R L +++RL+ A ARL + +   KED  +
Sbjct: 681 LSTEAARVLQDFYLELRKQSQRLNSSPITT-RQLESLIRLTEARARLELREEATKEDAED 739

Query: 633 AIRLMEMS 640
            + +M+ S
Sbjct: 740 IVEIMKYS 747


>gi|33469924 minichromosome maintenance complex component 8 isoform
           2 [Homo sapiens]
          Length = 824

 Score =  255 bits (652), Expect = 9e-68
 Identities = 173/543 (31%), Positives = 272/543 (50%), Gaps = 69/543 (12%)

Query: 149 IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 208
           ++ VRA+  GK + +RG V RVS +KP      + C  CG     P+    +     CP 
Sbjct: 207 LKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKYSLPTKCPV 266

Query: 209 QECQTNRSGGRLYLQTRGSRF---IKFQEMKMQE--HSDQVPVGNIPRSITVLVEGENTR 263
             C+     GR +   R S     + +Q +K+QE    DQ   G IPR+I   +  +   
Sbjct: 267 PVCR-----GRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVD 321

Query: 264 IAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELTREE 323
              PGD V++TGI           V      E    ++   +  KS +D    G L    
Sbjct: 322 SCVPGDTVTITGI-----------VKVSNAEEANSISNSKGQKTKSSEDGCKHGMLMEFS 370

Query: 324 LRQI-------AEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQ---SPRGMKIRG 373
           L+ +       AEE+ ++ +  S+ P I+GHE VK  L L L GG  +       + IRG
Sbjct: 371 LKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRG 430

Query: 374 NINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGA 433
           + +I ++GDPG+ KSQ+L     +APR  Y  G  ++  GLT  + +DS SG+  LE GA
Sbjct: 431 DPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGA 490

Query: 434 LVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYG 493
           LVL DQG+C IDEFDKM      A+ E MEQQ+IS+AKAG++ +L AR SI+AAANP  G
Sbjct: 491 LVLGDQGICGIDEFDKMGN-QHQALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGG 549

Query: 494 RYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQ------- 546
            YN  +++ +N+++ +ALLSRFDL++++ D P+  +D  L++H+  +    ++       
Sbjct: 550 HYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHVIAIRAGKQRTISSATV 609

Query: 547 ----------------------------PPSQFEPLDMKLMRRYIAMCRE-KQPMVPESL 577
                                       P    +P+  +L+R+YI   R+   P +    
Sbjct: 610 ARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDPIPHQLLRKYIGYARQYVYPRLSTEA 669

Query: 578 ADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLM 637
           A  +   Y+E+R+++     +  T+ R L +++RL+ A ARL + +   KED  + + +M
Sbjct: 670 ARVLQDFYLELRKQSQRLNSSPITT-RQLESLIRLTEARARLELREEATKEDAEDIVEIM 728

Query: 638 EMS 640
           + S
Sbjct: 729 KYS 731


>gi|23397546 minichromosome maintenance complex component 9 [Homo
           sapiens]
          Length = 391

 Score =  116 bits (290), Expect = 8e-26
 Identities = 88/288 (30%), Positives = 149/288 (51%), Gaps = 28/288 (9%)

Query: 146 PRVIRE--VRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPI---QSPTF 200
           P ++RE   +   VG  ++V G V R S VK       Y C++C           Q  TF
Sbjct: 107 PELVREHIPKTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFVIKADFEQYYTF 166

Query: 201 MPLIMCPSQE-CQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEG 259
                CPS E C +++      L +  +R   +QE+K+QE   ++ VG+IPRS+ V++E 
Sbjct: 167 CRPSSCPSLESCDSSKFTCLSGLSSSPTRCRDYQEIKIQEQVQRLSVGSIPRSMKVILED 226

Query: 260 ENTRIAQPGDHVSVTGIFLPILRTGFRQVVQGLLSETYLEAHRIVKMNKSE-DDESGAGE 318
           +     + GD +++ GI +   +  F+Q V+        E   ++K N  + ++E  +G 
Sbjct: 227 DLVDSCKSGDDLTIYGIVMQRWKP-FQQDVR-------CEVEIVLKANYIQVNNEQSSGI 278

Query: 319 LTREELRQIAEEDFYEK-----------LAASIAPEIYGHEDVKKALLLLLVGGVDQSPR 367
           +  EE+++   EDF+E            + AS+ P+++G   VK A+ ++L GG+ ++  
Sbjct: 279 IMDEEVQK-EFEDFWEYYKSDPFAGRNVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDA 337

Query: 368 -GMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGL 414
            G ++RG  ++ L+GDPG  KSQ L Y  ++ PRS  TTG GS+  G+
Sbjct: 338 TGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGI 385


>gi|31543667 suppressor of var1, 3-like 1 [Homo sapiens]
          Length = 786

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 37/141 (26%), Positives = 61/141 (43%), Gaps = 21/141 (14%)

Query: 8   LEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVAL--YVDLDDVAEDDPELV-D 64
           L+K +VKK L +FY+  E+ K    YG    RL H+  ++   Y+      + D  +V +
Sbjct: 88  LDKNEVKKVLDKFYKRKEIQKLGADYGLD-ARLFHQAFISFRNYIMQSHSLDVDIHIVLN 146

Query: 65  SICENARRYAKLFADAVQELLPQYKEREVVNKDVLDVYIEHRLMMEQRSRDPGMVRSPQN 124
            IC  A            +L P +         VLD   + R + +        +R P N
Sbjct: 147 DICFGAAH--------ADDLFPFFLRHAKQIFPVLDCKDDLRKISD--------LRIPPN 190

Query: 125 QYP-AELMRRFELYFQGPSSN 144
            YP A  M+R  ++  GP+++
Sbjct: 191 WYPDARAMQRKIIFHSGPTNS 211


>gi|193082991 GTP binding protein 3 (mitochondrial) isoform V [Homo
           sapiens]
          Length = 492

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 39/173 (22%), Positives = 76/173 (43%), Gaps = 26/173 (15%)

Query: 352 KALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSG 411
           +AL + L   +  + RG ++R  +++ + G P   KS L++ + R          +  S 
Sbjct: 227 RALQVALGAHLRDARRGQRLRSGVHVVVTGPPNAGKSSLVNLLSR----------KPVSI 276

Query: 412 VGLTAAVLRDSVSGELTLEGGALVLAD-----QGVCCIDEFDKMAEADRTAIHEVMEQQT 466
           V       RD +   + L G  ++L+D     +GV  +++     E  R A  E +EQ  
Sbjct: 277 VSPEPGTTRDVLETPVDLAGFPVLLSDTAGLREGVGPVEQ-----EGVRRA-RERLEQAD 330

Query: 467 ISIAKAGILTTLN-ARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLL 518
           + +A        + + C+ LA    + G  +P  S ++ +     +L++ DLL
Sbjct: 331 LILAMLDASDLASPSSCNFLATVVASVGAQSPSDSSQRLL----LVLNKSDLL 379


>gi|193082988 GTP binding protein 3 (mitochondrial) isoform IV [Homo
           sapiens]
          Length = 524

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 39/173 (22%), Positives = 76/173 (43%), Gaps = 26/173 (15%)

Query: 352 KALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSG 411
           +AL + L   +  + RG ++R  +++ + G P   KS L++ + R          +  S 
Sbjct: 259 RALQVALGAHLRDARRGQRLRSGVHVVVTGPPNAGKSSLVNLLSR----------KPVSI 308

Query: 412 VGLTAAVLRDSVSGELTLEGGALVLAD-----QGVCCIDEFDKMAEADRTAIHEVMEQQT 466
           V       RD +   + L G  ++L+D     +GV  +++     E  R A  E +EQ  
Sbjct: 309 VSPEPGTTRDVLETPVDLAGFPVLLSDTAGLREGVGPVEQ-----EGVRRA-RERLEQAD 362

Query: 467 ISIAKAGILTTLN-ARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLL 518
           + +A        + + C+ LA    + G  +P  S ++ +     +L++ DLL
Sbjct: 363 LILAMLDASDLASPSSCNFLATVVASVGAQSPSDSSQRLL----LVLNKSDLL 411


>gi|92091575 coiled-coil domain containing 57 [Homo sapiens]
          Length = 915

 Score = 32.0 bits (71), Expect = 2.1
 Identities = 26/94 (27%), Positives = 42/94 (44%), Gaps = 4/94 (4%)

Query: 9   EKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVALYVD----LDDVAEDDPELVD 64
           E+ K+K  +    QD E  K+Q     +  R   R+QV L +D     DD+  D  +  +
Sbjct: 387 EEVKLKAQVARSQQDIERYKQQLSLAVERERSLERDQVQLGLDWQRRCDDIERDQIQKSE 446

Query: 65  SICENARRYAKLFADAVQELLPQYKEREVVNKDV 98
           ++ +         A  +QE     +E+EVV K V
Sbjct: 447 ALIQGLSMAKSQVAAKLQETEQALQEQEVVLKAV 480


>gi|58761544 amine oxidase (flavin containing) domain 2 isoform a
           [Homo sapiens]
          Length = 876

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 17/59 (28%), Positives = 32/59 (54%)

Query: 10  KEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVALYVDLDDVAEDDPELVDSICE 68
           KEK+K+  Q++ +  E+   +      LV+  HR+  AL  + D++AE   +L + + E
Sbjct: 476 KEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQE 534


>gi|58761546 amine oxidase (flavin containing) domain 2 isoform b
           [Homo sapiens]
          Length = 852

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 17/59 (28%), Positives = 32/59 (54%)

Query: 10  KEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHREQVALYVDLDDVAEDDPELVDSICE 68
           KEK+K+  Q++ +  E+   +      LV+  HR+  AL  + D++AE   +L + + E
Sbjct: 452 KEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQE 510


>gi|32698692 zinc finger, DHHC domain containing 8 [Homo sapiens]
          Length = 765

 Score = 30.8 bits (68), Expect = 4.6
 Identities = 27/101 (26%), Positives = 39/101 (38%), Gaps = 5/101 (4%)

Query: 616 LARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADVIFATVRELVSG--GR 673
           L+R  M  + E++D  E  RL+    DSL GD G       P+         L  G  G 
Sbjct: 544 LSRTIMASIQERKDREERERLLRSQADSLFGDSGV---YDAPSSYSLQQASVLSEGPRGP 600

Query: 674 SVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRT 714
           ++R+   +      GF  A+  A       L+     A RT
Sbjct: 601 ALRYGSRDDLVAGPGFGGARNPALQTSLSSLSSSVSRAPRT 641


>gi|21396489 mitochondrial lon peptidase 1 [Homo sapiens]
          Length = 959

 Score = 30.4 bits (67), Expect = 6.0
 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 7/67 (10%)

Query: 338 ASIAPEIYGHEDVKKALL-LLLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDR 396
           A +  + YG EDVKK +L  + V  +  S +G KI     +C  G PGV K+ +   I R
Sbjct: 485 AVLEEDHYGMEDVKKRILEFIAVSQLRGSTQG-KI-----LCFYGPPGVGKTSIARSIAR 538

Query: 397 LAPRSQY 403
              R  +
Sbjct: 539 ALNREYF 545


>gi|73623035 sperm associated antigen 5 [Homo sapiens]
          Length = 1193

 Score = 30.4 bits (67), Expect = 6.0
 Identities = 30/124 (24%), Positives = 51/124 (41%), Gaps = 13/124 (10%)

Query: 543 HSRQPPSQFEPLDMKLMRRYIAMCREKQPMV------PESLADYITAAYVEMRREAWASK 596
           H+ Q  SQ E  D+  MR +  + ++ Q  +       E L    T +     ++ W S 
Sbjct: 591 HASQRISQLEQ-DLASMREFRGLLKDAQTQLVGLHAKQEELVQQ-TVSLTSTLQQDWRSM 648

Query: 597 DATYTSARTLLAILRLSTALARLRMVDVVEKEDV-----NEAIRLMEMSKDSLLGDKGQT 651
              YT+   LL+  R  T    ++    +++ DV      E  R++E     L   KGQT
Sbjct: 649 QLDYTTWTALLSRSRQLTEKLTVKSQQALQERDVAIEEKQEVSRVLEQVSAQLEECKGQT 708

Query: 652 ARTQ 655
            + +
Sbjct: 709 EQLE 712


>gi|53729339 mitochondrial translational initiation factor 2
           precursor [Homo sapiens]
          Length = 727

 Score = 30.0 bits (66), Expect = 7.8
 Identities = 33/127 (25%), Positives = 56/127 (44%), Gaps = 13/127 (10%)

Query: 278 LPILRTGFRQVVQG----LLSETYLEAHRIVKMNKSEDDESGAGELTREELRQIAEEDFY 333
           +P+  TG+R +       L  E+   A  +V   K E ++    E  +E+L+ I E+   
Sbjct: 414 MPVGITGWRDLPSAGEEILEVESEPRAREVVDWRKYEQEQ----EKGQEDLKIIEEKRKE 469

Query: 334 EKLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGMKIRGN-----INICLMGDPGVAKS 388
            K A   A E YGH   KK  +L  +   +Q P   K +       +++ + GD   +  
Sbjct: 470 HKEAHQKAREKYGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVE 529

Query: 389 QLLSYID 395
            +L+ ID
Sbjct: 530 AILNIID 536


>gi|53729337 mitochondrial translational initiation factor 2
           precursor [Homo sapiens]
          Length = 727

 Score = 30.0 bits (66), Expect = 7.8
 Identities = 33/127 (25%), Positives = 56/127 (44%), Gaps = 13/127 (10%)

Query: 278 LPILRTGFRQVVQG----LLSETYLEAHRIVKMNKSEDDESGAGELTREELRQIAEEDFY 333
           +P+  TG+R +       L  E+   A  +V   K E ++    E  +E+L+ I E+   
Sbjct: 414 MPVGITGWRDLPSAGEEILEVESEPRAREVVDWRKYEQEQ----EKGQEDLKIIEEKRKE 469

Query: 334 EKLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGMKIRGN-----INICLMGDPGVAKS 388
            K A   A E YGH   KK  +L  +   +Q P   K +       +++ + GD   +  
Sbjct: 470 HKEAHQKAREKYGHLLWKKRSILRFLERKEQIPLKPKEKRERDSNVLSVIIKGDVDGSVE 529

Query: 389 QLLSYID 395
            +L+ ID
Sbjct: 530 AILNIID 536


>gi|4506221 proteasome 26S non-ATPase subunit 12 isoform 1 [Homo
           sapiens]
          Length = 456

 Score = 30.0 bits (66), Expect = 7.8
 Identities = 14/44 (31%), Positives = 25/44 (56%)

Query: 1   MALKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHRE 44
           +A+KDY   +   KK   +F+Q++   K + KY N +++L   E
Sbjct: 194 LAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHE 237


>gi|28872765 proteasome 26S non-ATPase subunit 12 isoform 2 [Homo
           sapiens]
          Length = 436

 Score = 30.0 bits (66), Expect = 7.8
 Identities = 14/44 (31%), Positives = 25/44 (56%)

Query: 1   MALKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVRLAHRE 44
           +A+KDY   +   KK   +F+Q++   K + KY N +++L   E
Sbjct: 174 LAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHE 217


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,486,432
Number of Sequences: 37866
Number of extensions: 1110809
Number of successful extensions: 2873
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2815
Number of HSP's gapped (non-prelim): 30
length of query: 719
length of database: 18,247,518
effective HSP length: 110
effective length of query: 609
effective length of database: 14,082,258
effective search space: 8576095122
effective search space used: 8576095122
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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