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Search of human proteins with 33356174
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33356174 pinin, desmosome associated protein [Homo sapiens]
(717 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 1377 0.0
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 101 2e-21
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 101 2e-21
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 100 4e-21
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 100 6e-21
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 98 3e-20
gi|148746195 trichohyalin [Homo sapiens] 97 7e-20
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 96 2e-19
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 94 4e-19
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 94 6e-19
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 91 4e-18
gi|169166609 PREDICTED: similar to ribonucleic acid binding prot... 90 6e-18
gi|113415994 PREDICTED: similar to ribonucleic acid binding prot... 90 6e-18
gi|6857826 RNA-binding protein S1, serine-rich domain [Homo sapi... 90 6e-18
gi|18379334 RNA-binding protein S1, serine-rich domain [Homo sap... 90 6e-18
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 90 8e-18
gi|221219020 NYD-SP11 protein [Homo sapiens] 89 1e-17
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 89 1e-17
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 89 1e-17
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 89 1e-17
gi|113415504 PREDICTED: similar to ribonucleic acid binding prot... 88 2e-17
gi|169166499 PREDICTED: similar to ribonucleic acid binding prot... 88 2e-17
gi|113415498 PREDICTED: similar to ribonucleic acid binding prot... 88 2e-17
gi|88973230 PREDICTED: similar to ribonucleic acid binding prote... 88 2e-17
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 87 7e-17
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 86 9e-17
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 86 9e-17
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 86 1e-16
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 84 3e-16
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 84 6e-16
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 1377 bits (3563), Expect = 0.0
Identities = 717/717 (100%), Positives = 717/717 (100%)
Query: 1 MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLL 60
MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLL
Sbjct: 1 MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLL 60
Query: 61 LRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATS 120
LRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATS
Sbjct: 61 LRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATS 120
Query: 121 KERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQ 180
KERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQ
Sbjct: 121 KERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQ 180
Query: 181 AEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPH 240
AEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPH
Sbjct: 181 AEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPH 240
Query: 241 LFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRN 300
LFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRN
Sbjct: 241 LFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRN 300
Query: 301 EEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQ 360
EEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQ
Sbjct: 301 EEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQ 360
Query: 361 EMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENE 420
EMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENE
Sbjct: 361 EMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENE 420
Query: 421 ASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQS 480
ASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQS
Sbjct: 421 ASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQS 480
Query: 481 QPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEV 540
QPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEV
Sbjct: 481 QPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEV 540
Query: 541 PVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGS 600
PVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGS
Sbjct: 541 PVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGS 600
Query: 601 SSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGL 660
SSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGL
Sbjct: 601 SSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGL 660
Query: 661 ERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR 717
ERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR
Sbjct: 661 ERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR 717
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 101 bits (252), Expect = 2e-21
Identities = 128/489 (26%), Positives = 207/489 (42%), Gaps = 87/489 (17%)
Query: 276 EQINKMEARPRR----QSMKEKEHQVVRNEEQKAEQEEG----KVAQR-----EEELEET 322
E + KME ++ + M+++ Q+ + E++ E EG ++ QR +EE E+T
Sbjct: 238 EGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDT 297
Query: 323 GNQHNDVEIEEAGEEEEKEIAIV---HSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQ 379
N VE +G+ + HSD E +EE+E + + KM
Sbjct: 298 EN----VEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKM------------- 340
Query: 380 DSQPEEVMDVLEMVENVKHVIADQEVMETNR-VESVEPSENEASKELEPEMEFEIEPDKE 438
E ++DV + E + +V D T + + S AS + D E
Sbjct: 341 -LLTEILLDVTD--EEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSE 397
Query: 439 CKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQP 498
+ G E+ D E ++++E+ + E Q Q + + Q + +
Sbjct: 398 DERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNE 457
Query: 499 PSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKT 558
E SL++L+ + G ++ E+K P E+ + E P+ + K K
Sbjct: 458 FIHKEQNSLSLLE----AREADGDVVNEKKRTPNETTSVLE----------PKKEHKEKE 503
Query: 559 RSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSS 618
+ +GR+R+ +S S S SS+S +SS+SST SSS SSSSG SSR+SS SSS
Sbjct: 504 K---QGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSG--SSRTSSRSSSPKRKKRH 558
Query: 619 RDSSSSTSSSSESRSRSRGRG------------HNRDRKHRRSVDRKRRDTSGLERSHKS 666
S S T + SRSRS R +R R +R S++R+RR R +
Sbjct: 559 SRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRR 618
Query: 667 SKGGSSRDTKGSKDKNSRSDRKRSI------------------SESSRSGKRSSRSERDR 708
S+ SRD + ++ SRS +R I E R +RS ++DR
Sbjct: 619 SR-SRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDR 677
Query: 709 KSDRKDKRR 717
K K++ R
Sbjct: 678 KKKDKERER 686
Score = 75.9 bits (185), Expect = 1e-13
Identities = 119/630 (18%), Positives = 240/630 (38%), Gaps = 98/630 (15%)
Query: 139 KQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEE 198
KQ +I + TL + +E ER+K+++ ++++E ++R Q+ + ++ E+
Sbjct: 218 KQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERME----QQRSQLSKKEKKATED 273
Query: 199 RRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEE 258
A+ + L Q+ + +EE + N + + P +P + EE
Sbjct: 274 --AEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSP--VPQEEHSDPEMTEEE 329
Query: 259 SQRKMNALFEGRRIEFA-----EQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVA 313
+ +M L + E E+I + R++ K Q+ ++ + G +
Sbjct: 330 KEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLG 389
Query: 314 -----QREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEE 368
E+E + G++ +D + EE ++++E ++E E ++
Sbjct: 390 GYGSGDSEDERSDRGSESSDTDDEELRHRI------------RQKQEAFWRKEKEQQLLH 437
Query: 369 ETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPE 428
+ ++ E ++Q + +E+ + + +N ++ +E + + V + + NE + LEP+
Sbjct: 438 DKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREA-DGDVVNEKKRTPNETTSVLEPK 496
Query: 429 MEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQS 488
E + E +K+ +S S + S+ + S S S
Sbjct: 497 KEHK-EKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSS-----------------SYSS 538
Query: 489 QSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVES----VKLTEVPVEP 544
S S S P+ +P + + + +ES VK+ +
Sbjct: 539 SSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSN 598
Query: 545 VLTVHPE-------SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSS 597
++ E S+ + ++RSRSR R N+ S+SRSR + S +S
Sbjct: 599 RNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKG 658
Query: 598 SGSSSSRSSSSSSSSTSGSSSRDSSSSTS-----------------SSSESRSRSRGRG- 639
R S S +D SS + R + +
Sbjct: 659 EAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESE 718
Query: 640 ---------------HNRDRKHRRSVDRKRRDTSGLERSHKSS--KGGSSRDTKGSKDKN 682
H+ + ++S + + SG + S +SS GSS++ K K K+
Sbjct: 719 RTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKH 778
Query: 683 SRSDRKRSISESSRSGKRSSRSERDRKSDR 712
SRS RS+ +S RSGK++SR + + R
Sbjct: 779 SRS---RSVEKSQRSGKKASRKHKSKSRSR 805
Score = 48.9 bits (115), Expect = 2e-05
Identities = 72/432 (16%), Positives = 168/432 (38%), Gaps = 42/432 (9%)
Query: 73 PAKQRDLEGAVSRL----------GGERRTRRESR--QESDPEDDDVKKPALQSSVVATS 120
PAKQ A++ L G+ R R + SD +D++++ Q
Sbjct: 369 PAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWR 428
Query: 121 KERTRRDLIQDQNMDEKGKQRNRRIFGLL----------MGTLQKFKQESTVATERQKRR 170
KE+ ++ L+ D+ M+E+ KQ+ R+ + + L+ + + V E+++
Sbjct: 429 KEKEQQ-LLHDKQMEEE-KQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTP 486
Query: 171 QEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKII 230
E LE + E + K+ + R + + R ++ + +++
Sbjct: 487 NETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTS 546
Query: 231 ----------KYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRR-----IEFA 275
++ R+++ P + R ++++ ES R + + RR IE
Sbjct: 547 SRSSSPKRKKRHSRSRS-PTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERE 605
Query: 276 EQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQH-NDVEIEEA 334
+ N+ +R RR+S + + ++ K+ + L ++H + + +E
Sbjct: 606 RRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQER 665
Query: 335 GEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVE 394
+E + I +KE+E E+ K++ + K EE+ S+ + + E
Sbjct: 666 KKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSG 725
Query: 395 NVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIE-PDKECKSLSPGKENVSALD 453
++ I + + ++ + + S+ + + E KE K+ P +++
Sbjct: 726 SISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVE 785
Query: 454 MEKESEEKEEKE 465
+ S +K ++
Sbjct: 786 KSQRSGKKASRK 797
Score = 33.5 bits (75), Expect = 0.70
Identities = 44/235 (18%), Positives = 98/235 (41%), Gaps = 34/235 (14%)
Query: 91 RTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIF---- 146
R RR S + S + + + + S+ R RR N + + R+RR
Sbjct: 592 RDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRT-----NRASRSRSRDRRKIDDQR 646
Query: 147 GLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTEL 206
G L G K K E+ + Q+R++E + ++ +++ K+ E E+ + E+++ ++ +
Sbjct: 647 GNLSGNSHKHKGEA----KEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDF 702
Query: 207 RLLEQKVELAQLQEE---WNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKM 263
+ Q L + +E ++ + +K IR ++ + + ++S++
Sbjct: 703 KFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQ----------DSKKSTTKDSKKHS 752
Query: 264 NALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEE 318
+ GR + E+ + K K+ + R+ + Q GK A R+ +
Sbjct: 753 GSDSSGR--------SSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHK 799
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 101 bits (252), Expect = 2e-21
Identities = 128/489 (26%), Positives = 207/489 (42%), Gaps = 87/489 (17%)
Query: 276 EQINKMEARPRR----QSMKEKEHQVVRNEEQKAEQEEG----KVAQR-----EEELEET 322
E + KME ++ + M+++ Q+ + E++ E EG ++ QR +EE E+T
Sbjct: 238 EGLEKMEREKQKKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDT 297
Query: 323 GNQHNDVEIEEAGEEEEKEIAIV---HSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQ 379
N VE +G+ + HSD E +EE+E + + KM
Sbjct: 298 EN----VEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKM------------- 340
Query: 380 DSQPEEVMDVLEMVENVKHVIADQEVMETNR-VESVEPSENEASKELEPEMEFEIEPDKE 438
E ++DV + E + +V D T + + S AS + D E
Sbjct: 341 -LLTEILLDVTD--EEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLGGYGSGDSE 397
Query: 439 CKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQP 498
+ G E+ D E ++++E+ + E Q Q + + Q + +
Sbjct: 398 DERSDRGSESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNE 457
Query: 499 PSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKT 558
E SL++L+ + G ++ E+K P E+ + E P+ + K K
Sbjct: 458 FIHKEQNSLSLLE----AREADGDVVNEKKRTPNETTSVLE----------PKKEHKEKE 503
Query: 559 RSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSS 618
+ +GR+R+ +S S S SS+S +SS+SST SSS SSSSG SSR+SS SSS
Sbjct: 504 K---QGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSG--SSRTSSRSSSPKRKKRH 558
Query: 619 RDSSSSTSSSSESRSRSRGRG------------HNRDRKHRRSVDRKRRDTSGLERSHKS 666
S S T + SRSRS R +R R +R S++R+RR R +
Sbjct: 559 SRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRR 618
Query: 667 SKGGSSRDTKGSKDKNSRSDRKRSI------------------SESSRSGKRSSRSERDR 708
S+ SRD + ++ SRS +R I E R +RS ++DR
Sbjct: 619 SR-SRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDR 677
Query: 709 KSDRKDKRR 717
K K++ R
Sbjct: 678 KKKDKERER 686
Score = 75.9 bits (185), Expect = 1e-13
Identities = 119/630 (18%), Positives = 240/630 (38%), Gaps = 98/630 (15%)
Query: 139 KQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEE 198
KQ +I + TL + +E ER+K+++ ++++E ++R Q+ + ++ E+
Sbjct: 218 KQEPPQIDAVKRRTLPAWIREGLEKMEREKQKKLEKERME----QQRSQLSKKEKKATED 273
Query: 199 RRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEE 258
A+ + L Q+ + +EE + N + + P +P + EE
Sbjct: 274 --AEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSP--VPQEEHSDPEMTEEE 329
Query: 259 SQRKMNALFEGRRIEFA-----EQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVA 313
+ +M L + E E+I + R++ K Q+ ++ + G +
Sbjct: 330 KEYQMMLLTKMLLTEILLDVTDEEIYYVAKDAHRKATKAPAKQLAQSSALASLTGLGGLG 389
Query: 314 -----QREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEE 368
E+E + G++ +D + EE ++++E ++E E ++
Sbjct: 390 GYGSGDSEDERSDRGSESSDTDDEELRHRI------------RQKQEAFWRKEKEQQLLH 437
Query: 369 ETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPE 428
+ ++ E ++Q + +E+ + + +N ++ +E + + V + + NE + LEP+
Sbjct: 438 DKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREA-DGDVVNEKKRTPNETTSVLEPK 496
Query: 429 MEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQS 488
E + E +K+ +S S + S+ + S S S
Sbjct: 497 KEHK-EKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSS-----------------SYSS 538
Query: 489 QSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVES----VKLTEVPVEP 544
S S S P+ +P + + + +ES VK+ +
Sbjct: 539 SSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSN 598
Query: 545 VLTVHPE-------SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSS 597
++ E S+ + ++RSRSR R N+ S+SRSR + S +S
Sbjct: 599 RNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKG 658
Query: 598 SGSSSSRSSSSSSSSTSGSSSRDSSSSTS-----------------SSSESRSRSRGRG- 639
R S S +D SS + R + +
Sbjct: 659 EAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESE 718
Query: 640 ---------------HNRDRKHRRSVDRKRRDTSGLERSHKSS--KGGSSRDTKGSKDKN 682
H+ + ++S + + SG + S +SS GSS++ K K K+
Sbjct: 719 RTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKH 778
Query: 683 SRSDRKRSISESSRSGKRSSRSERDRKSDR 712
SRS RS+ +S RSGK++SR + + R
Sbjct: 779 SRS---RSVEKSQRSGKKASRKHKSKSRSR 805
Score = 48.9 bits (115), Expect = 2e-05
Identities = 72/432 (16%), Positives = 168/432 (38%), Gaps = 42/432 (9%)
Query: 73 PAKQRDLEGAVSRL----------GGERRTRRESR--QESDPEDDDVKKPALQSSVVATS 120
PAKQ A++ L G+ R R + SD +D++++ Q
Sbjct: 369 PAKQLAQSSALASLTGLGGLGGYGSGDSEDERSDRGSESSDTDDEELRHRIRQKQEAFWR 428
Query: 121 KERTRRDLIQDQNMDEKGKQRNRRIFGLL----------MGTLQKFKQESTVATERQKRR 170
KE+ ++ L+ D+ M+E+ KQ+ R+ + + L+ + + V E+++
Sbjct: 429 KEKEQQ-LLHDKQMEEE-KQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTP 486
Query: 171 QEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKII 230
E LE + E + K+ + R + + R ++ + +++
Sbjct: 487 NETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTS 546
Query: 231 ----------KYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRR-----IEFA 275
++ R+++ P + R ++++ ES R + + RR IE
Sbjct: 547 SRSSSPKRKKRHSRSRS-PTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERE 605
Query: 276 EQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQH-NDVEIEEA 334
+ N+ +R RR+S + + ++ K+ + L ++H + + +E
Sbjct: 606 RRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQER 665
Query: 335 GEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVE 394
+E + I +KE+E E+ K++ + K EE+ S+ + + E
Sbjct: 666 KKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESERTFSRSG 725
Query: 395 NVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIE-PDKECKSLSPGKENVSALD 453
++ I + + ++ + + S+ + + E KE K+ P +++
Sbjct: 726 SISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVE 785
Query: 454 MEKESEEKEEKE 465
+ S +K ++
Sbjct: 786 KSQRSGKKASRK 797
Score = 33.5 bits (75), Expect = 0.70
Identities = 44/235 (18%), Positives = 98/235 (41%), Gaps = 34/235 (14%)
Query: 91 RTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIF---- 146
R RR S + S + + + + S+ R RR N + + R+RR
Sbjct: 592 RDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRT-----NRASRSRSRDRRKIDDQR 646
Query: 147 GLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTEL 206
G L G K K E+ + Q+R++E + ++ +++ K+ E E+ + E+++ ++ +
Sbjct: 647 GNLSGNSHKHKGEA----KEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDF 702
Query: 207 RLLEQKVELAQLQEE---WNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKM 263
+ Q L + +E ++ + +K IR ++ + + ++S++
Sbjct: 703 KFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQ----------DSKKSTTKDSKKHS 752
Query: 264 NALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEE 318
+ GR + E+ + K K+ + R+ + Q GK A R+ +
Sbjct: 753 GSDSSGR--------SSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHK 799
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 100 bits (250), Expect = 4e-21
Identities = 96/436 (22%), Positives = 211/436 (48%), Gaps = 57/436 (13%)
Query: 97 RQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKF 156
R++ + + +K Q ++ +E+ RR Q++ M EK +++ RR ++ +K
Sbjct: 324 REQEEKIREQEEKMRRQEEMMWEKEEKMRR---QEEMMWEK-EEKMRRQEEMMWEKEEKM 379
Query: 157 KQESTVATERQKRRQEIEQKL----EVQAEEERKQVENERRELFEERRAKQTELRLLEQK 212
+++ + E++++ +E+E+K+ +++ +EE++Q E + RE +E+R +Q E ++ Q+
Sbjct: 380 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE--QEKRQEQ-EAKMWRQE 436
Query: 213 VELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNA------- 265
++ + +E+ E K+ R + K H +K+ EE +R+
Sbjct: 437 EKIREQEEKIREQEKKMW---RQEEKIH----------EQEKIREEEKRQEQEEMWRQEE 483
Query: 266 -LFEGRRI--------EFAEQINKMEARPRRQSMKEKEHQV-VRNEEQKAEQEEGKVAQR 315
+ E I E E+I K E + RQ K +E + +R +E+K ++E K+ ++
Sbjct: 484 KIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQ 543
Query: 316 EEELEETGNQHNDVEIEEAGEEEEKEIAI-------------VHSDAEKEQEEEEQKQEM 362
EE E H +I E + +E+E + V EK +E+EE++QE
Sbjct: 544 EEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQ 603
Query: 363 EVKM-EEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEA 421
E KM ++E ++RE E++ Q E++ + E + + + +QE + E + E +
Sbjct: 604 EEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKM 663
Query: 422 SKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQ 481
++ E E + ++ K + +E + + E+ +E+EEK E + + Q + +
Sbjct: 664 QEQEETMWRQEEKIREQEKKIREQEEKIR--EQEEMMQEQEEKMWEQEEKMCEQEEKMQE 721
Query: 482 PQLQLQSQSQPVLQSQ 497
+ +++ Q + + + +
Sbjct: 722 QEEKMRRQEEKMWEQE 737
Score = 86.7 bits (213), Expect = 7e-17
Identities = 79/351 (22%), Positives = 162/351 (46%), Gaps = 29/351 (8%)
Query: 89 ERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEK-GKQRNRRIFG 147
E+R E +E + + K Q + +E+ R + +EK +Q R
Sbjct: 411 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 470
Query: 148 LLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVEN----ERRELFEERRAKQ 203
+ ++QE + + + RQ+ +K+ Q E+ RKQ E E + +E + ++
Sbjct: 471 KRQEQEEMWRQEEKIHEQEEIWRQK--EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIRE 528
Query: 204 TELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKM 263
E ++ Q+ ++ + +E W E K+ + + + +M +K+ E+ ++
Sbjct: 529 QEEKMWRQEEKIREQEEMWREEE-KMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVW 587
Query: 264 NALFEGRRIEFAEQINKMEARPRRQSMKE-KEHQVVRNEEQKAEQEEGKVAQREEELEET 322
E+I + E + + Q K K+ + +R +E+K +++E K+ ++EE++ E
Sbjct: 588 RQ---------EEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQ 638
Query: 323 GNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQ 382
+ E E+ GE+EEK EQEE+ Q+QE E +E ++RE EK+ Q
Sbjct: 639 EEMTQEQE-EKMGEQEEKMC---------EQEEKMQEQE-ETMWRQEEKIREQEKKIREQ 687
Query: 383 PEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEI 433
E++ + EM++ + + +QE + E ++ E + ++ E E E+
Sbjct: 688 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Score = 75.1 bits (183), Expect = 2e-13
Identities = 107/449 (23%), Positives = 206/449 (45%), Gaps = 56/449 (12%)
Query: 82 AVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQR 141
AV +L GE R +S ++++ S VAT K++ D+ ++E K+R
Sbjct: 152 AVKQLEGEARDLISRLHDSWKFAGELEQAL---SAVATQKKKA------DRYIEELTKER 202
Query: 142 NRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRA 201
+ L T+ E +++ ++++KL++ E E+ +++ +EL +R+
Sbjct: 203 DALSLELYRNTITD--------EELKEKNAKLQEKLQL-VESEKSEIQLNVKEL--KRKL 251
Query: 202 KQTELRLLEQKV--ELAQLQEEWNEHNAKIIKYIR-TKTKPHLFYIPGRMCPATQKLIEE 258
++ +L L +Q++ E L +E +AK+ + + L ++ I+E
Sbjct: 252 ERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE 311
Query: 259 SQRKMNALFEGRRIEFAEQINKMEARPRRQS--MKEKEHQVVRNEEQKAEQEEGKVAQRE 316
+ K+ E R E E+I + E + RRQ M EKE ++ R EE E+EE K+ ++E
Sbjct: 312 WEEKIQEQEEKIR-EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE-KMRRQE 369
Query: 317 E---ELEETGNQHNDV---------EIEEAGEEEEKEIAIVHSDAEKEQEEE-----EQK 359
E E EE + ++ E+EE E+EK + EK QEEE E++
Sbjct: 370 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK----IREQEEKRQEEEKIREQEKR 425
Query: 360 QEMEVKM-EEETEVRESEKQQDSQPEEVMDVLEMV---ENVKHVIADQEVMETNRVESVE 415
QE E KM +E ++RE E++ Q +++ E + E ++ QE E R E
Sbjct: 426 QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 485
Query: 416 PSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQ 475
+ E ++ E E E + K+ + + +E + E+E + +E++E + E +
Sbjct: 486 HEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKI----REQEEKIREQEEKMWRQEEKIR 541
Query: 476 PQPQSQPQLQLQSQSQPVLQSQPPSQPED 504
Q + + + + + + + + + ED
Sbjct: 542 EQEEMWREEEKMHEQEKIWEEEKRQEQED 570
Score = 60.5 bits (145), Expect = 5e-09
Identities = 72/349 (20%), Positives = 158/349 (45%), Gaps = 55/349 (15%)
Query: 160 STVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQ 219
S VAT+++K + IE E+ E + +E R + +E ++ L++K++L + +
Sbjct: 182 SAVATQKKKADRYIE---ELTKERDALSLELYRNTITDEELKEKNAK--LQEKLQLVESE 236
Query: 220 EEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQIN 279
+ + N K +K R + L+ + Q + A G+ ++
Sbjct: 237 KSEIQLNVKELK---------------RKLERAKLLLPQQQLQAEADHLGKELQSVSA-- 279
Query: 280 KMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEE 339
K++A+ + + +Q +E+K ++E K+ + EE+++E EE E+E
Sbjct: 280 KLQAQVEENELWNRLNQ---QQEEKMWRQEEKIQEWEEKIQEQ---------EEKIREQE 327
Query: 340 KEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHV 399
++I +EQEE+ ++QE E+ E+E ++R E+ + E++ EM+ +
Sbjct: 328 EKI--------REQEEKMRRQE-EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 378
Query: 400 IADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESE 459
+ QE M + E + +ELE +M E E +E + +E + + +E E
Sbjct: 379 MRRQEEMMWEKEEKI--------RELEEKMH-EQEKIREQEEKRQEEEKIREQEKRQEQE 429
Query: 460 EK---EEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDL 505
K +E++ Q E + + + + Q + + + + + + + E++
Sbjct: 430 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEM 478
Score = 43.1 bits (100), Expect = 9e-04
Identities = 37/173 (21%), Positives = 76/173 (43%), Gaps = 22/173 (12%)
Query: 75 KQRDLEGAVSRLGGERRTRRESRQESDPE--------DDDVKKPALQSSVVATSKERTRR 126
K R+ E V R + R + E RQE + + + +K Q + +E+ R
Sbjct: 578 KIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIRE 637
Query: 127 DLIQDQNMDEKGKQRNRRIFG----------LLMGTLQKFKQESTVATERQKRRQEIEQK 176
Q +EK ++ ++ + +K +++ E++++ +E E+
Sbjct: 638 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEM 697
Query: 177 LEVQAE----EERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEH 225
++ Q E +E K E E + +E + ++ E ++ EQ+V L Q +E+ EH
Sbjct: 698 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 100 bits (248), Expect = 6e-21
Identities = 149/624 (23%), Positives = 251/624 (40%), Gaps = 74/624 (11%)
Query: 148 LLMGTLQKFK------QESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFE-ERR 200
L++ LQK Q ++ E + I+Q LE Q E R+++E E RE E E
Sbjct: 106 LMLENLQKHSTPHAAFQPNSQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEA 165
Query: 201 AKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQ 260
+ ++E ++ + + L ++ + + + I + + + +
Sbjct: 166 SAESEDEMIHPEGVASLLPPDFQSSLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGE 225
Query: 261 RKMNALFEGRRIEFAEQINKMEARPRRQS----MKEKEHQVVRNEEQKAEQEEGKVAQRE 316
R+ + + + R + +E E +++ ++ + + ++ EE++ E+EE + E
Sbjct: 226 RRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEE 285
Query: 317 EELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVK------MEEET 370
EE ++ G + + I + +EE +EI V + ++ + + QE EV +
Sbjct: 286 EEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQE 345
Query: 371 EVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVES---VEPSENEASKELEP 427
E R+S + Q +E+ + E + + + Q + E ++ S + +AS P
Sbjct: 346 EARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALP 405
Query: 428 EM---EFEIEPD---KECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQ-- 479
E E E P KE S P + SEE+ E P P + Q P
Sbjct: 406 EQTASEEETPPPLLTKEASSPPPHPQ--------LHSEEEIEPMEGPAPPVLIQLSPPNT 457
Query: 480 ---------SQPQLQL-------QSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQE-QGH 522
SQ +QL S S +S PE+ L ++Q + Q
Sbjct: 458 DADTRELLVSQHTVQLVGGLSPLSSPSDTKAESPAEKVPEESVLPLVQKSTLADYSAQKD 517
Query: 523 LLPE--RKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSS 580
L PE R P+ +K+ E+ + +T E K + + GR + T R S
Sbjct: 518 LEPESDRSAQPLP-LKIEELALAKGIT---EECLKQPSLEQKEGRRASHTLLPSHRLKQS 573
Query: 581 SSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTS-------------S 627
+ SSSS +SSSS SSS S S S SS S S S S RD + + + S
Sbjct: 574 ADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRS 633
Query: 628 SSESRSRSRGRGHNRDRKHRRSVD-RKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSD 686
+SESRSRSR R + R+S+ RD+S K G T
Sbjct: 634 TSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTETKDPSSGQEVATPPVPQLQVCEP 693
Query: 687 RKR-SISESSRSGKRSSRSERDRK 709
++R S S SS +R S+ E K
Sbjct: 694 KERTSTSSSSVQARRLSQPESAEK 717
Score = 52.4 bits (124), Expect = 1e-06
Identities = 81/446 (18%), Positives = 158/446 (35%), Gaps = 57/446 (12%)
Query: 296 QVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEE 355
QVV E Q+ Q E + ++E E E VE+ E + + D +
Sbjct: 923 QVVPAEGQENGQREEEEEEKEPEAEPPVPPQVSVEVALPPPAEHEVKKVTLGDTLTRRSI 982
Query: 356 EEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVE-----NVKHVIAD-----QEV 405
+QK + + +++ + + ++ + +V +K ++ +E
Sbjct: 983 SQQKSGVSITIDDPVRTAQVPSPPRGKISNIVHISNLVRPFTLGQLKELLGRTGTLVEEA 1042
Query: 406 METNRVES---VEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALD------MEK 456
++++S V S E + + P K L LD +++
Sbjct: 1043 FWIDKIKSHCFVTYSTVEEAVATRTALHGVKWPQSNPKFLCADYAEQDELDYHRGLLVDR 1102
Query: 457 ESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQV 516
SE K E++ P+P P P PQ P ++ + AV + +
Sbjct: 1103 PSETKTEEQGIPRPLHPPPPPPVQPPQ-------------HPRAEQREQERAVREQWAER 1149
Query: 517 TQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSR 576
+E R + + K+ E P ++RSRSR R R + +KS+ +
Sbjct: 1150 EREMERRERTRSEREWDRDKVREGP---------------RSRSRSRDRRRKERAKSKEK 1194
Query: 577 SSSSSSSSSSSTSSSSGSSSSSGSSSS-------RSSSSSSSSTSGSSSRDSSSSTSSSS 629
S + + + ++ + S + + R
Sbjct: 1195 KSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKE 1254
Query: 630 ESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKR 689
+ + R +R+ R ++R++R ER + + RD +G +D++ DR+R
Sbjct: 1255 QEEEEQKEREKEAERERNRQLEREKRREHSRERDRERER-ERERD-RGDRDRDRERDRER 1312
Query: 690 SISESSRSGKRSSRSERDRKSDRKDK 715
R KR SRS R R + +D+
Sbjct: 1313 GRERDRRDTKRHSRS-RSRSTPVRDR 1337
Score = 50.8 bits (120), Expect = 4e-06
Identities = 132/699 (18%), Positives = 258/699 (36%), Gaps = 96/699 (13%)
Query: 50 PGGGRGRGSLLLR-RGFSDSGGGPPAKQRDLEGAVSR---------LGGERRTRRESRQE 99
P G R S + + R S G PA++ + + SR L E E +E
Sbjct: 221 PRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEE 280
Query: 100 SDPED---DDVKKPALQSSVVATSKERTRR--DLIQDQNMDEKGKQRNRRIFGLLMGTLQ 154
D E+ DD + + ++ ++ KE + ++ MDE+ K R++ L G
Sbjct: 281 EDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRF 340
Query: 155 KFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLE--QK 212
QE + +++QE E K EEE +++++ + +E+ + RL E +K
Sbjct: 341 TRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQG--LKEKSKSPSPPRLTEDRKK 398
Query: 213 VELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRI 272
L L E+ +T P L P +L E + + EG
Sbjct: 399 ASLVALPEQTASEE---------ETPPPLLTKEASSPPPHPQLHSEEEIEP---MEGPAP 446
Query: 273 EFAEQIN--KMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVE 330
Q++ +A R + + Q+V + + K E++ E
Sbjct: 447 PVLIQLSPPNTDADTRELLVSQHTVQLVGGLSPLSSPSDTKAESPAEKVPEE-------- 498
Query: 331 IEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVL 390
++ +A + + E E + Q + +K+EE + ++ QP L
Sbjct: 499 -SVLPLVQKSTLADYSAQKDLEPESDRSAQPLPLKIEELALAKGITEECLKQPS-----L 552
Query: 391 EMVENVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVS 450
E E + A ++ ++R++ S + S +S SP S
Sbjct: 553 EQKEGRR---ASHTLLPSHRLKQSADSSSSRSSS-------SSSSSSRSRSRSPDSSG-S 601
Query: 451 ALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVL 510
S++++ ++ P +P+ S+ + +S+S+ +S + + LS
Sbjct: 602 RSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLS---- 657
Query: 511 QPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPE-----SKSKTKTRSRSRGR 565
P V+++ E KD P ++ PV + P+ S S + R S+
Sbjct: 658 ---PGVSRDSSTSYTETKD-PSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQPE 713
Query: 566 ARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSST 625
+ K R + S + + +++ +S +++S S + + T
Sbjct: 714 SAEKHVTQRLQPERGSPKKCEAEEAEPPAATQPQTSETQTSHLPESERIHHTVEEKEEVT 773
Query: 626 SSSSESRSRSR--------GRGHNRDRKHRRSVDRKRRDTSGLERSHK-------SSKG- 669
+SE+R + + D + SV+ + + S L +S K ++KG
Sbjct: 774 MDTSENRPENDVPEPPMPIADQVSNDDRPEGSVEDEEKKESSLPKSFKRKISVVSATKGV 833
Query: 670 -GSSRDTKGSKDKNSR--------SDRKRSISESSRSGK 699
+ DT+G + R + +K SIS ++ S K
Sbjct: 834 PAGNSDTEGGQPGRKRRWGASTATTQKKPSISITTESLK 872
Score = 48.1 bits (113), Expect = 3e-05
Identities = 48/224 (21%), Positives = 94/224 (41%), Gaps = 33/224 (14%)
Query: 157 KQESTVATERQKRRQEIEQKLEVQAEEE--RKQVENERRELFEER-RAKQTELRLLEQKV 213
+QE V + +R +E+E++ ++E E R +V R R R ++ + E+K
Sbjct: 1137 EQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKS 1196
Query: 214 ELAQLQEEWNEHNAKIIK--YIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRR 271
E + +E E AK++ + +TK P ++++P QK E ++R
Sbjct: 1197 EKKEKAQE--EPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAER---------- 1244
Query: 272 IEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEI 331
A+ R + KE+E EEQK ++E + + + E +H+
Sbjct: 1245 -----------AKEREKRRKEQEE-----EEQKEREKEAERERNRQLEREKRREHSRERD 1288
Query: 332 EEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRES 375
E E E++ D E+++E ++ + K + R +
Sbjct: 1289 RERERERERDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRST 1332
Score = 47.0 bits (110), Expect = 6e-05
Identities = 39/189 (20%), Positives = 84/189 (44%), Gaps = 16/189 (8%)
Query: 210 EQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEG 269
EQ+ + ++E+W E ++ + RT+++ R P ++ + +RK A +
Sbjct: 1134 EQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKE 1193
Query: 270 RRIEFAEQ-------------INKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQRE 316
++ E E+ K +A P + + Q+V+ E ++AE+ + + +R+
Sbjct: 1194 KKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRK 1253
Query: 317 EELEETGNQHNDVEIEEAGEEEEKEIAIVHS---DAEKEQEEEEQKQEMEVKMEEETEVR 373
E+ EE + E + E+E HS D E+E+E E + + + E + E
Sbjct: 1254 EQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERG 1313
Query: 374 ESEKQQDSQ 382
++D++
Sbjct: 1314 RERDRRDTK 1322
Score = 42.0 bits (97), Expect = 0.002
Identities = 42/166 (25%), Positives = 69/166 (41%), Gaps = 25/166 (15%)
Query: 72 PPAKQRDLEGAVSRLGGERRTRRESRQESDPE---DDDVKKPALQSSVVATSKERTRRDL 128
P A+QR+ E AV ER E R+ + E D D + +S + + R R
Sbjct: 1131 PRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAK 1190
Query: 129 IQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTV--------------------ATERQK 168
+++ ++K K + LL +K K + A ER+K
Sbjct: 1191 SKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREK 1250
Query: 169 RRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVE 214
RR+E E+ E Q E E++ R+L E+R + + R E++ E
Sbjct: 1251 RRKEQEE--EEQKEREKEAERERNRQLEREKRREHSRERDRERERE 1294
Score = 38.5 bits (88), Expect = 0.022
Identities = 38/150 (25%), Positives = 61/150 (40%), Gaps = 42/150 (28%)
Query: 271 RIEFAEQINKMEARPRRQSMKEKEHQVVRN------------EEQKAEQEEGKVAQREEE 318
R ++AE+ +ME R R +S +E + VR +++A+ +E K ++E+
Sbjct: 1143 REQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKA 1202
Query: 319 LEE------------------------TGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQE 354
EE T +Q E E A +E+E KEQE
Sbjct: 1203 QEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKERE------KRRKEQE 1256
Query: 355 EEEQKQEMEVKMEEETEVRESEKQQDSQPE 384
EEEQK+ + E E EK+++ E
Sbjct: 1257 EEEQKEREKEAERERNRQLEREKRREHSRE 1286
Score = 34.7 bits (78), Expect = 0.32
Identities = 57/252 (22%), Positives = 91/252 (36%), Gaps = 53/252 (21%)
Query: 279 NKMEARPRRQSMKEKEH-----QVVRNEEQKAEQEEGKV-AQREEELEETGNQH-NDVEI 331
+ ++AR Q ++H Q R +K E EE + A + + ET H + E
Sbjct: 702 SSVQARRLSQPESAEKHVTQRLQPERGSPKKCEAEEAEPPAATQPQTSETQTSHLPESER 761
Query: 332 EEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEE----ETEVRESEKQQDSQPEEVM 387
EE++E+ + S+ E + E + ++ E V + EK++ S P+
Sbjct: 762 IHHTVEEKEEVTMDTSENRPENDVPEPPMPIADQVSNDDRPEGSVEDEEKKESSLPKSFK 821
Query: 388 DVLEMVENVKHVIADQEVME------------TNRVESVEPS---ENEASKELEPEM--- 429
+ +V K V A E + +PS E+ K L P++
Sbjct: 822 RKISVVSATKGVPAGNSDTEGGQPGRKRRWGASTATTQKKPSISITTESLKSLIPDIKPL 881
Query: 430 -----------------EFEIEP-------DKECKSLSPGKENVSALDMEKESEEKEEKE 465
E E E DK K + V A E E+EE+E
Sbjct: 882 AGQEAVVDLHADDSRISEDETERNGDDGTHDKGLKICRTVTQVVPAEGQENGQREEEEEE 941
Query: 466 SEPQPEPVAQPQ 477
EP+ EP PQ
Sbjct: 942 KEPEAEPPVPPQ 953
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 97.8 bits (242), Expect = 3e-20
Identities = 94/401 (23%), Positives = 202/401 (50%), Gaps = 49/401 (12%)
Query: 75 KQRDLEGAVSRLGGERRTRRESRQESDPE--DDDVKKPALQSSVVATSKERTRRDLIQDQ 132
++ +L +++ E+ R+E + + E + +K Q + +E+ RR Q++
Sbjct: 347 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR---QEE 403
Query: 133 NMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKL----EVQAEEERKQV 188
M EK +++ RR ++ +K +++ + E++++ +E+E+K+ +++ +EE++Q
Sbjct: 404 MMWEK-EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 462
Query: 189 ENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRM 248
E + RE +E+R +Q E ++ Q+ ++ + +E+ E K+ R + K H
Sbjct: 463 EEKIRE--QEKRQEQ-EAKMWRQEEKIREQEEKIREQEEKMW---RQEEKIH-------- 508
Query: 249 CPATQKLIEESQRKMNALFEGRRIEFAEQ---------INKMEARPRRQSMK-----EKE 294
+K+ EE +R+ + + EQ I++ E + R+Q K EK
Sbjct: 509 --EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKM 566
Query: 295 H---QVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEK 351
H + +R +E+K ++E K+ ++EE++ E + + E E E+EEK + EK
Sbjct: 567 HDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQE-EMTQEQEEK----MGEQEEK 621
Query: 352 EQEEEEQKQEMEVKME-EETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNR 410
E+EE+ QE E KM +E ++RE EK+ Q E++ + EM++ + + +QE +
Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 681
Query: 411 VESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSA 451
E ++ E + ++ E E E+ ++ + + +E++ A
Sbjct: 682 EEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
Score = 95.1 bits (235), Expect = 2e-19
Identities = 86/382 (22%), Positives = 182/382 (47%), Gaps = 39/382 (10%)
Query: 156 FKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRE---LFEERRAKQTELRLLEQK 212
++QE + E +++ QE E+K+ Q E+ R+Q E RR+ ++E+ + + ++ +K
Sbjct: 364 WRQEEKIQ-EWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK 422
Query: 213 VELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRI 272
E + QEE + I+ + K +K+ E+ +++ E +I
Sbjct: 423 EEKMRRQEEMMWEKEEKIRELEEKMHEQ------------EKIREQEEKRQ----EEEKI 466
Query: 273 EFAEQINKMEARPRRQSMK---------EKEHQVVRNEEQKAEQEEGKVAQREEELEETG 323
E+ + EA+ RQ K E+E ++ R EE+ EQE+ + ++ +E EE
Sbjct: 467 REQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMW 526
Query: 324 NQHNDV-EIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKM-EEETEVRESEKQQDS 381
Q + E EE ++EK +H EK +++EE+ E KM ++E ++RE E++
Sbjct: 527 RQEEKIREQEEIWRQKEK----IHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWR 582
Query: 382 QPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKS 441
Q E++ + E + + I +QE M + E + E + ++ E E E + ++ +
Sbjct: 583 QEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEK 642
Query: 442 LSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQ 501
+ ++ + + E++ E+EE E + + Q + + + ++Q Q + + + +
Sbjct: 643 IREQEKKIR--EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMW 700
Query: 502 PEDLSLAVLQPTPQVTQEQGHL 523
+++ L Q ++ + Q HL
Sbjct: 701 EQEVRLR--QQEEKMQEHQEHL 720
Score = 82.4 bits (202), Expect = 1e-15
Identities = 116/465 (24%), Positives = 207/465 (44%), Gaps = 53/465 (11%)
Query: 82 AVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQR 141
AV +L GE R +S ++++ S VAT K++ D+ ++E K+R
Sbjct: 213 AVKQLEGEARDLISRLHDSWKFAGELEQAL---SAVATQKKKA------DRYIEELTKER 263
Query: 142 NRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRA 201
+ L T+ E +++ ++++KL++ E E+ +++ +EL +R+
Sbjct: 264 DALSLELYRNTITD--------EELKEKNAKLQEKLQL-VESEKSEIQLNVKEL--KRKL 312
Query: 202 KQTELRLLEQKV--ELAQLQEEWNEHNAKIIKYIR-TKTKPHLFYIPGRMCPATQKLIEE 258
++ +L L +Q++ E L +E +AK+ + + L ++ I+E
Sbjct: 313 ERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE 372
Query: 259 SQRKMNALFEGRRIEFAEQINKMEARPRRQS--MKEKEHQVVRNEEQKAEQEEGKVAQRE 316
+ K+ E R E E+I + E + RRQ M EKE ++ R EE E+EE K+ ++E
Sbjct: 373 WEEKIQEQEEKIR-EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE-KMRRQE 430
Query: 317 EELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEE-----EQKQEMEVKM----- 366
E + E + E+EE E+EK + EK QEEE E++QE E KM
Sbjct: 431 EMMWE--KEEKIRELEEKMHEQEK----IREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 484
Query: 367 ---EEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASK 423
E+E ++RE E++ Q E++ + ++ E K +QE M + E E K
Sbjct: 485 KIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKR--QEQEEMWRQEEKIREQEEIWRQK 542
Query: 424 ELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQ 483
E E E +I +E ++ D E++ E+EEK Q E + + + + + Q
Sbjct: 543 EKIHEQEEKIRKQEE----KMWRQEEKMHDQEEKIREQEEKVWR-QEEKIREQEEKIREQ 597
Query: 484 LQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERK 528
+ + + + Q Q E Q QE+ E K
Sbjct: 598 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEK 642
Score = 75.5 bits (184), Expect = 2e-13
Identities = 89/473 (18%), Positives = 203/473 (42%), Gaps = 54/473 (11%)
Query: 78 DLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEK 137
+LE A+S + +++ +E E D + ++++ + L + + E
Sbjct: 237 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 296
Query: 138 GKQRNRRIFGLLMGTLQKFK------QESTVATERQKRRQEIEQKLEVQAEEE----RKQ 187
K + L L++ K Q A K Q + KL+ Q EE R
Sbjct: 297 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 356
Query: 188 VENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGR 247
+ E + +E + ++ E ++ EQ+ ++ + +E+ E K+ + + + +
Sbjct: 357 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM------RRQEEMMWEKEE 410
Query: 248 MCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQ 307
++++ E + KM E E E+I ++E + M E+E ++ EE++ Q
Sbjct: 411 KMRRQEEMMWEKEEKMRRQ-EEMMWEKEEKIRELE-----EKMHEQE-KIREQEEKR--Q 461
Query: 308 EEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKME 367
EE K+ ++E+ E+ + +EEK + EK +E+EE+ E K+
Sbjct: 462 EEEKIREQEKRQEQEA---------KMWRQEEK----IREQEEKIREQEEKMWRQEEKIH 508
Query: 368 EETEVRESEKQQDS-----------QPEEVMDVLEMVENVKHVIADQEVMETNRVESVEP 416
E+ ++RE EK+Q+ + EE+ E + + I QE + E +
Sbjct: 509 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHD 568
Query: 417 SENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQP 476
E + ++ E E + ++ + + +E + + E+ ++E+EEK E + + Q
Sbjct: 569 QEEKIREQEEKVWRQEEKIREQEEKIREQEEKIR--EQEEMTQEQEEKMGEQEEKMCEQE 626
Query: 477 QPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKD 529
+ + + +++ Q + + + + + ++ ++ ++ QEQ + E+++
Sbjct: 627 EKMQEQEEKMRRQEEKIREQEKKIREQE---EKIREQEEMMQEQEEKMWEQEE 676
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 96.7 bits (239), Expect = 7e-20
Identities = 137/648 (21%), Positives = 278/648 (42%), Gaps = 66/648 (10%)
Query: 89 ERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIFGL 148
E++ +R RQ+ ++++ K+ + +V+ +E+ + + Q Q ++ +++ R+ L
Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK---L 281
Query: 149 LMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRL 208
L++ +QE E+Q++R EQ+L + EEER++ + ERRE +ERR +Q E R
Sbjct: 282 ERQELRRERQEE----EQQQQRLRREQQLRRKQEEERREQQEERREQ-QERREQQEERR- 335
Query: 209 LEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFE 268
EQ QL+ E E + ++ + + + + +E +R+ L
Sbjct: 336 -EQ-----QLRREQEERREQQLRREQEEERRE----------QQLRREQEEERREQQLRR 379
Query: 269 GRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQ-REEELEETGNQHN 327
+++ +Q+ + E + RR+ +E Q+ R ++ + EQ+ + Q R E+ EE Q +
Sbjct: 380 EQQLRREQQLRR-EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKH 438
Query: 328 DVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQ---KQEMEVKMEEETEVR-----ESEKQQ 379
+ E E + E+E E+E E EQ KQ+++ EEE R E E+++
Sbjct: 439 EQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERRE 498
Query: 380 DSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKE--------LEPEMEF 431
+ E E E + + QE E R++ SE + +E L+ E E
Sbjct: 499 QQERREQQLRREQEERREQRLKRQE--EEERLQQRLRSEQQLRREQEERREQLLKREEEK 556
Query: 432 EIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQ-PQLQLQSQS 490
+E ++ + L +E +++E E ++++ Q E + Q + + +L+ + +
Sbjct: 557 RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERR 616
Query: 491 QPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHP 550
+ L+ + P E+ +L+ Q + Q L E+++ + +K E +
Sbjct: 617 EQRLKREEPE--EERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEER----LEQ 670
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
K + + R + A + ++R R S S + + S S R
Sbjct: 671 RLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQR 730
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHR-RSVDRKRRDTSGLERSHKSSKG 669
R R S + +R HR + + +RRD + ++ + S+
Sbjct: 731 RRQEQEEKR-----------RRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSER 779
Query: 670 GSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR 717
G R + + R + R +E + ++ E + K R+ +RR
Sbjct: 780 GRQRLSARPPLREQRERQLR--AEERQQREQRFLPEEEEKEQRRRQRR 825
Score = 95.9 bits (237), Expect = 1e-19
Identities = 137/653 (20%), Positives = 255/653 (39%), Gaps = 60/653 (9%)
Query: 89 ERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIFGL 148
E R R+ ++E D + A + S + R L + + + ++R +R
Sbjct: 751 EERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRF 810
Query: 149 LMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRL 208
L +K +Q ER+K Q +E++ ++Q E +Q++ E L E++ ++++ +
Sbjct: 811 LPEEEEK-EQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQR 869
Query: 209 LEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFE 268
+QK QL+EE K + H Y PA Q+ + + Q+ +
Sbjct: 870 RDQKWRW-QLEEE-------------RKRRRHTLYAK----PALQEQLRKEQQLLQ---- 907
Query: 269 GRRIEFAEQINKMEARPRRQSMKEK----EHQVVRNEEQKAEQEEGKVAQREEELEETGN 324
E E++ + E RR+ +E+ E Q+ + EEQ +E K ++E E + +
Sbjct: 908 ----EEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKD 963
Query: 325 QHNDVEIEEA-GEEEEKEIAIVHSDAEKEQEEEEQ-KQEMEVKMEEETEVRESE------ 376
+ + E+ GEE EK + EK+ EEE+ +QE E + EE E R +
Sbjct: 964 KKLQQKEEQLLGEEPEKRR---RQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQY 1020
Query: 377 -KQQDSQPEEVMDVLE------MVENVKHVIADQEVMETNRVESVEPSENEASKELEPEM 429
K+ + Q EE + E + E + ++E+ + E E +ELE +
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQY 1080
Query: 430 EFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQ 489
E E +E + L +E E+E + +EE+E + + E + + + + + + +L+ Q
Sbjct: 1081 RKEEELQQEEEQLL-REEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ 1139
Query: 490 SQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVH 549
+ + Q E+ L +P + QE E ++ E +L E
Sbjct: 1140 ----YREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
Query: 550 PESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSS 609
+ + R + + R + RS + + +
Sbjct: 1196 ERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED 1255
Query: 610 SSSTSGSSSRDSSSSTSSSSE-SRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSK 668
S S +D E R + R R RDR +R + +R + S+
Sbjct: 1256 SQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQ 1315
Query: 669 GGSS--RDTKGSKDKNSRSDRKRSISE---SSRSGKRSSRSERDRKSDRKDKR 716
R+ + K + +DRK E R + R ERDRK ++ R
Sbjct: 1316 EEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELR 1368
Score = 90.9 bits (224), Expect = 4e-18
Identities = 107/503 (21%), Positives = 227/503 (45%), Gaps = 47/503 (9%)
Query: 8 LQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLLLRRGFSD 67
LQE+ + + L+ +E +RKL ++ R + + R R LRR +
Sbjct: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ-------RLRREQQLRRKQEE 312
Query: 68 SGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRD 127
++R+ + ERR ++E R+E + ++ Q + +E R
Sbjct: 313 ERREQQEERREQQ--------ERREQQEERREQQLRREQEERREQQ--LRREQEEERREQ 362
Query: 128 LIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRR-QEIEQKLEVQAEEERK 186
++ + +E+ +Q+ RR L Q+ ++E + E+Q RR Q++ ++ +++ E++ +
Sbjct: 363 QLRREQEEERREQQLRREQQLRRE--QQLRREQQLRREQQLRREQQLRREQQLRREQQLR 420
Query: 187 QVENERRELFEERRAKQTELRLLEQKVELAQLQE-EWNEHNAKIIKYIRTKTKPHLFYIP 245
+ + RRE EER ++ E EQ+++ Q + +W + + ++ + + K L
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
Query: 246 GRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKA 305
+EE +R+ +++ EQ + E R +RQ +E+ Q +R+E+Q
Sbjct: 481 EEERRERWLKLEEEERREQQERREQQLR-REQEERREQRLKRQEEEERLQQRLRSEQQLR 539
Query: 306 EQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVK 365
++E +R E+L + EEEK + + ++E+EE++ ++ +K
Sbjct: 540 REQE----ERREQLLK--------------REEEKRLEQERREQRLKREQEERRDQL-LK 580
Query: 366 MEEETEVRESEKQQDSQPE-----EVMDVLEMVENVKHVIADQEVMETNRVESVEPSENE 420
EEE + +++Q+ + E E ++ LE E + + +E E R + ++ E E
Sbjct: 581 REEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQE 640
Query: 421 ASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQS 480
++ + E + ++ K + L E E E +E++ +E + E +
Sbjct: 641 ERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSR 700
Query: 481 QPQLQLQSQSQ-PVLQSQPPSQP 502
P+ Q Q +S+ QS+ S+P
Sbjct: 701 IPKWQWQLESEADARQSKVYSRP 723
Score = 89.4 bits (220), Expect = 1e-17
Identities = 102/499 (20%), Positives = 209/499 (41%), Gaps = 45/499 (9%)
Query: 16 KESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLLLRRGFS--------- 66
K+ LKN+ E R P+D + + L L GR + L F
Sbjct: 30 KKDLKNLLEREFGAVLRRPHDPKTVDLILELLDLDSNGRVDFNEFLLFIFKVAQACYYAL 89
Query: 67 -DSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTR 125
+ G K+ +G S L + R + E ++ +P D +++ Q ++
Sbjct: 90 GQATGLDEEKRARCDGKESLL--QDRRQEEDQRRFEPRDRQLEEEPGQRR--RQKRQEQE 145
Query: 126 RDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEER 185
R+L + + EK ++ +R L + +QE ER+ ++++ + EE
Sbjct: 146 RELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFP 205
Query: 186 KQVENERRELFEERRA----KQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHL 241
+ + RREL E RR KQ + R + +V + ++EW + + K
Sbjct: 206 DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRK---------- 255
Query: 242 FYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNE 301
+KL EE ++ L E E ++ + E R RQ ++++ ++ R +
Sbjct: 256 ---------EEEKLQEEEPQRQRELQEEE--EQLRKLERQELRRERQEEEQQQQRLRREQ 304
Query: 302 EQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQE 361
+ + +QEE + Q+EE E+ + E E E+E + + +E+EE+++E
Sbjct: 305 QLRRKQEEERREQQEERREQQERREQQEERREQQLRREQE---ERREQQLRREQEEERRE 361
Query: 362 MEVKMEEETEVRESE--KQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSEN 419
+++ E+E E RE + ++Q + E+ + + + + + +Q++ ++ +
Sbjct: 362 QQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 421
Query: 420 EASKELEPEME-FEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQP 478
E E E E E + ++E + +E D K EE E E E + + + + Q
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481
Query: 479 QSQPQLQLQSQSQPVLQSQ 497
+ + + L+ + + + Q
Sbjct: 482 EERRERWLKLEEEERREQQ 500
Score = 87.0 bits (214), Expect = 5e-17
Identities = 132/666 (19%), Positives = 254/666 (38%), Gaps = 72/666 (10%)
Query: 75 KQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNM 134
++R+ E + L E + +R R + E++D LQ + RRD +
Sbjct: 823 QRREREKELQFLEEEEQLQRRERAQQLQEEED----GLQEDQERRRSQEQRRDQKWRWQL 878
Query: 135 DEKGKQRNRRIFG--LLMGTLQKFKQ------ESTVATERQKRRQEIEQKLEVQAEEERK 186
+E+ K+R ++ L L+K +Q E ER+KRR++ EQ+ + + EE+ +
Sbjct: 879 EEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQ-EQERQYREEEQLQ 937
Query: 187 QVENERRELFEERRAKQTELRLLEQKVELAQLQEEW-NEHNAKIIKYIRTKTKPHLFYIP 245
Q E + E+R +Q R + +L Q +E+ E K + R K +
Sbjct: 938 QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKK----YREE 993
Query: 246 GRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKA 305
+ ++L+ E + K RR E+ Q K + ++++E Q++R E +K
Sbjct: 994 EELQQEEEQLLREEREKR------RRQEWERQYRK------KDELQQEEEQLLREEREKR 1041
Query: 306 E-QEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEV 364
QE + + EEEL++ Q E E +E + KE+E +++++++
Sbjct: 1042 RLQERERQYREEEELQQEEEQLLGEERETRRRQE------LERQYRKEEELQQEEEQLLR 1095
Query: 365 KMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKE 424
+ E+ +E E+Q + E + +++ + QE+ R E E E
Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155
Query: 425 LEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQL 484
EPE E +++ + ++ L E++ + ++E+E + + E Q Q + Q
Sbjct: 1156 EEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYR 1215
Query: 485 QLQSQSQPVLQSQPPSQ------------PEDLSLAVLQPTP----QVTQEQGHLLPERK 528
+S Q +P + E+ L+ + Q Q+ HLL E++
Sbjct: 1216 DEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQ 1275
Query: 529 DFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSST 588
+ E + + + + R K +K R R S
Sbjct: 1276 ERDREQERR-----------RWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREE 1324
Query: 589 SSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRR 648
+ R E R + +GR + + R
Sbjct: 1325 REEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLR 1384
Query: 649 SVDRKR---RDTSGLERSHKSSKGGSSRDTKGSKDKN--SRSDRKRSISESSRSGKRSSR 703
+R+R ++ L + + RD K +++ SR +R R E + + R
Sbjct: 1385 RQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR---R 1441
Query: 704 SERDRK 709
ER+RK
Sbjct: 1442 QERERK 1447
Score = 84.0 bits (206), Expect = 5e-16
Identities = 116/645 (17%), Positives = 260/645 (40%), Gaps = 54/645 (8%)
Query: 89 ERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIFGL 148
+ R R + R PE++ +++ + + K R R+ + Q + E+ +++ RR
Sbjct: 1281 QERRRWQQRDRHFPEEEQLEREEQKEA-----KRRDRKSQEEKQLLREEREEKRRR---- 1331
Query: 149 LMGTLQKFKQESTVATERQK---RRQEIEQKLEVQA----EEERKQVENERRELFEERRA 201
T +KF++E + ER++ RRQE ++K + E+ RK +E E+R +ER
Sbjct: 1332 -QETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERER 1390
Query: 202 K----QTELRLLEQKVELAQLQE-EWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLI 256
K + +LR E++ +L Q ++ ++ E ++ + R + K R +K +
Sbjct: 1391 KFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDR-KFREEEQQVRRQERERKFL 1449
Query: 257 EESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQRE 316
EE Q+ L + R +F E+ ++ R +Q +++ + EEQ+ ++E RE
Sbjct: 1450 EEEQQ----LRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFRE 1505
Query: 317 EELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEE--EEQKQEMEVKMEEETEVRE 374
+EL + +E E+ ++++ + + + ++E ++++Q+ + K EE ++R+
Sbjct: 1506 QELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQ 1565
Query: 375 SEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIE 434
++Q +E + K + +Q+V + E + ++ E + + E
Sbjct: 1566 EREEQQLSRQE--------RDRKFRLEEQKVRRQEQERKFMEDEQQLRRQ-EGQQQLRQE 1616
Query: 435 PDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVL 494
D++ + + + ++ +++ E EPQ + Q + + + + +L
Sbjct: 1617 RDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLL 1676
Query: 495 QSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKD--FPVESVKLTEVPVEPVLTVHPES 552
Q + E+ L + + +E+ L + ++ F E +L +E +
Sbjct: 1677 Q-----EGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQL 1731
Query: 553 KSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSS 612
+ +T+ R K + R S
Sbjct: 1732 RQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791
Query: 613 TSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSS 672
S R+ E + R + RD K+R ++ + LE + +
Sbjct: 1792 ESDRKFREEEQLRQEREEQQLRPQ----QRDGKYRWEEEQLQ-----LEEQEQRLRQERD 1842
Query: 673 RDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR 717
R + + ++ +R E + ++ R ER+RK + RR
Sbjct: 1843 RQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRR 1887
Score = 81.3 bits (199), Expect = 3e-15
Identities = 124/669 (18%), Positives = 260/669 (38%), Gaps = 75/669 (11%)
Query: 89 ERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIFGL 148
ER RR QE +++ + + + ++R R++ + D+K +Q+ ++ G
Sbjct: 917 EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLG- 975
Query: 149 LMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEE---RKQVENERRELFEERRAKQTE 205
E RQ+R ++ ++ E+Q EEE R++ E RR+ +E + K+ E
Sbjct: 976 ----------EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDE 1025
Query: 206 LR-----LLEQKVELAQLQE---------EWNEHNAKIIKYIR-TKTKPHL---FYIPGR 247
L+ LL ++ E +LQE E + +++ R T+ + L +
Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
Query: 248 MCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVV----RNEEQ 303
+ ++L+ E K R+ E++ + E + R+ +++ Q + R EE+
Sbjct: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEE 1145
Query: 304 KAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEME 363
++EE + + E+ + E EE +EEE+ + +EQE+ Q++E +
Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLL-------REEQEKRRQERERQ 1198
Query: 364 VKMEEETEVRESEKQQDSQPEEVMDVLEMVENVK-HVIADQEVMETNRVESVEPSENEAS 422
+ EEE + R+ KQ+ ++ D+ E K + + D +V R ENE
Sbjct: 1199 YREEEELQ-RQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGR-------ENEQF 1250
Query: 423 KELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESE-PQPEPVAQPQPQSQ 481
++LE + + ++ + L ++ D E+E ++++ P+ E + + + +
Sbjct: 1251 RQLEDSQLRDRQSQQDLQHLLGEQQE---RDREQERRRWQQRDRHFPEEEQLEREEQKEA 1307
Query: 482 PQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVP 541
+ +SQ + L + + Q T + +E+ LL ER++ P+ +
Sbjct: 1308 KRRDRKSQEEKQLLREEREEKRR-----RQETDRKFREEEQLLQEREEQPLRRQERDRKF 1362
Query: 542 VEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSS 601
E L + + + R R + R + +
Sbjct: 1363 REEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQ 1422
Query: 602 SSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDR--------KHRRSVDRK 653
SR R E + + R H + R + + + R+
Sbjct: 1423 LSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQER-HRKFREEEQLLQEREEQQLHRQ 1481
Query: 654 RRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRK-----RSISESSRSGKRSSRSERDR 708
RD LE + + R + + ++ +RK + + R K ++ R
Sbjct: 1482 ERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLR 1541
Query: 709 KSDRKDKRR 717
+ +R +RR
Sbjct: 1542 RQERGQQRR 1550
Score = 80.5 bits (197), Expect = 5e-15
Identities = 100/464 (21%), Positives = 192/464 (41%), Gaps = 69/464 (14%)
Query: 120 SKERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEV 179
S+E R+ L ++Q + + +QR KF QE E+Q RRQE Q+
Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQR-------------KFLQE-----EQQLRRQERGQQRRQ 1551
Query: 180 QAEE---ERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTK 236
+ E +Q+ ER E R+ + + RL EQKV + + ++ E ++
Sbjct: 1552 DRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQL------- 1604
Query: 237 TKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQ 296
R Q+L +E RK E ++ + ++ + R + E+E Q
Sbjct: 1605 ----------RRQEGQQQLRQERDRKFR---EDEQLLQEREEQQLHRQERDRKFLEEEPQ 1651
Query: 297 VVRNE-EQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEE 355
+ R E EQ+ + + + EE+L + G + E + E+E + + E++ +
Sbjct: 1652 LRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ 1711
Query: 356 EEQ---KQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVE 412
EEQ +QE+E K EE ++R+ +Q+ L E + ++ ++++ R E
Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQEQ---------LRRQERYRKILEEEQL----RPE 1758
Query: 413 SVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEP 472
E ++ + E ++ ++E + L + + + E+ +E+EE++ PQ
Sbjct: 1759 REEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRD 1818
Query: 473 VAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPV 532
+ QLQL+ Q Q + Q + + A TQE+ E++ +
Sbjct: 1819 --GKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFA--------TQEKSR-REEQELWQE 1867
Query: 533 ESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSR 576
E K + + H + K + R R G +++ K R
Sbjct: 1868 EEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGR 1911
Score = 79.0 bits (193), Expect = 1e-14
Identities = 109/536 (20%), Positives = 234/536 (43%), Gaps = 26/536 (4%)
Query: 9 QEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLLLRRGFSDS 68
++ L++ +E+ ++ E ++ RD + R + L + R LRR +
Sbjct: 455 RDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEER 514
Query: 69 GGGPPAKQRDLEGAVSRLGGERRTRRES--RQESDPEDDDVKKPALQSSVVATSKERTRR 126
+Q + E RL E++ RRE R+E + ++ K+ + +E+ R
Sbjct: 515 REQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEER 574
Query: 127 DLIQDQNMDEKGKQRNRRIFGLLMGTL-QKFKQESTVATERQKRRQEIEQKLEVQAEEER 185
+DQ + + ++R +R+ L Q+ K+E E+++RR EQ+L+ + EE
Sbjct: 575 ---RDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERR---EQRLKREEPEEE 628
Query: 186 KQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIP 245
++ + + E EERR +Q E++ + + +EE E + +K + +
Sbjct: 629 RRQQLLKSEEQEERRQQQLRREQQERREQRLKREEE-EERLEQRLKREHEEERREQELAE 687
Query: 246 GRMCPATQKL---IEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEE 302
A +++ I + Q ++ + + R+ + + K E + RRQ +EK R E
Sbjct: 688 EEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRR---RRES 744
Query: 303 QKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEE--EEQKQ 360
+ QEE + ++++E E+ + + EE E + ++ E+ + + E++Q
Sbjct: 745 ELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQ 804
Query: 361 EMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENE 420
+ E + E E +E ++Q + E+ + LE E ++ Q++ E E E
Sbjct: 805 QREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQE-EEDGLQEDQERR 863
Query: 421 ASKELEPEMEFEIEPDKECKS------LSPGKENVSALDMEKESEEKEEKESEPQPEPVA 474
S+E + ++ + ++E K P + + + EE+EE + E + +
Sbjct: 864 RSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRR 923
Query: 475 QPQP-QSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKD 529
Q Q Q + + QLQ + + +L+ + + + ++ Q++ LL E +
Sbjct: 924 QEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPE 979
Score = 79.0 bits (193), Expect = 1e-14
Identities = 92/437 (21%), Positives = 195/437 (44%), Gaps = 68/437 (15%)
Query: 89 ERRTRRESR----QESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNM--DEKGKQRN 142
E++ RR+ R +E + + ++ L+ ++R R+ L ++Q + E+G+QR
Sbjct: 1491 EQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRR 1550
Query: 143 RRIFGLLMGTLQKFKQESTVATERQKR---RQEIEQKLEVQA------EEERKQVENERR 193
+ +KF++E + ER+++ RQE ++K ++ E+ERK +E+E++
Sbjct: 1551 Q-------DRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQ 1603
Query: 194 --------ELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIK----YIRTKTKPHL 241
+L +ER K E L Q+ E QL + E + K ++ R + + L
Sbjct: 1604 LRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQ--ERDRKFLEEEPQLRRQEREQQL 1661
Query: 242 FYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNE 301
+ R ++L++E + + E R +F E+ ++ + R + ++E Q+ R E
Sbjct: 1662 RHDRDRKFREEEQLLQEGEEQQLRRQERDR-KFREEEQQLRRQERERKFLQEEQQLRRQE 1720
Query: 302 -EQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQ-- 358
E+K +EE + E+E ++ + EE E +E + + +++ EEEQ
Sbjct: 1721 LERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLR 1780
Query: 359 ---------KQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETN 409
QE + K EE ++R+ ++Q +P++ + K+
Sbjct: 1781 QEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQ--------RDGKY----------- 1821
Query: 410 RVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQ 469
R E + E + L E + + +++ + + L E+E + ++E+E + +
Sbjct: 1822 RWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLR 1881
Query: 470 PEPVAQPQPQSQPQLQL 486
E + + Q + Q Q+
Sbjct: 1882 EEHIRRQQKEEQRHRQV 1898
Score = 72.8 bits (177), Expect = 1e-12
Identities = 89/446 (19%), Positives = 188/446 (42%), Gaps = 67/446 (15%)
Query: 94 RESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTL 153
RE+ Q ED ++ Q + E+ RD Q++ + +QR+R
Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERR---RWQQRDRH--------- 1292
Query: 154 QKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKV 213
F +E + E QK + ++K +E KQ+ E RE E+RR ++T+ + E++
Sbjct: 1293 --FPEEEQLEREEQKEAKRRDRK-----SQEEKQLLREERE--EKRRRQETDRKFREEEQ 1343
Query: 214 ELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRIE 273
L + +E+ P R +K EE R +GR+
Sbjct: 1344 LLQEREEQ-----------------------PLRRQERDRKFREEELRHQE---QGRKFL 1377
Query: 274 FAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEE 333
EQ + + R R+ +E++ + E+Q + + K + E++L E +
Sbjct: 1378 EEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQ-------ERDR 1430
Query: 334 AGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKM-EEETEVRESEKQQDSQPEEVMDVLEM 392
EEE+++ + + +EE++ +QE K EEE ++E E+QQ + E LE
Sbjct: 1431 KFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEE 1490
Query: 393 VENVKHVIADQEVMETNRVESVEPS----ENEASKELEPEMEFEIEPDKECKSLSPGKEN 448
+ ++ D++ E + S EP E E + ++ +++ + G++
Sbjct: 1491 EQQLRRQERDRKFRE-QELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQR 1549
Query: 449 VSALDMEKESEEKEEKESEPQPEPVAQPQPQ-----SQPQLQLQSQSQPVLQSQPPSQPE 503
D +++ E+E+ E + + +++ + + +++ Q Q + ++ + + +
Sbjct: 1550 --RQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQ 1607
Query: 504 DLSLAVLQPTPQVTQEQGHLLPERKD 529
+ + Q + +E LL ER++
Sbjct: 1608 EGQQQLRQERDRKFREDEQLLQEREE 1633
Score = 67.0 bits (162), Expect = 6e-11
Identities = 66/307 (21%), Positives = 141/307 (45%), Gaps = 17/307 (5%)
Query: 85 RLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRD--LIQDQNMDEKGKQRN 142
RL ++ R+E ++ ++ +++ Q + + R D L+Q++ + +Q
Sbjct: 1582 RLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQER 1641
Query: 143 RRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENER--RELFEERR 200
R F L++ ++E + +R ++ +E EQ L+ E++ ++ E +R RE ++ R
Sbjct: 1642 DRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLR 1701
Query: 201 AKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQ 260
++ E + L+++ QL+ + E + + +R +T+ R +K++EE Q
Sbjct: 1702 RQERERKFLQEE---QQLRRQELERKFREEEQLRQETEQEQL----RRQERYRKILEEEQ 1754
Query: 261 RKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEE--QKAEQEEGKVAQREEE 318
+ E + Q + R Q +E+E Q +R++E +K +EE +REE+
Sbjct: 1755 LRP----EREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQ 1810
Query: 319 LEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQ 378
+ EE + E++ + + +++ EEQ E EE E+ + E+Q
Sbjct: 1811 QLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQ 1870
Query: 379 QDSQPEE 385
+ Q E
Sbjct: 1871 KRRQERE 1877
Score = 31.2 bits (69), Expect = 3.5
Identities = 22/97 (22%), Positives = 41/97 (42%), Gaps = 4/97 (4%)
Query: 619 RDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGS 678
R + E +S + R RDR+ RR + R+ ER + ++ + KG
Sbjct: 141 RQEQERELAEGEEQSEKQERLEQRDRQ-RRDEELWRQRQEWQEREERRAEEEQLQSCKGH 199
Query: 679 KDKNSRSD---RKRSISESSRSGKRSSRSERDRKSDR 712
+ + + R+R + E R G+ + +R + DR
Sbjct: 200 ETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDR 236
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 95.5 bits (236), Expect = 2e-19
Identities = 90/403 (22%), Positives = 199/403 (49%), Gaps = 35/403 (8%)
Query: 75 KQRDLEGAVSRLGGERRTRRESRQESDPE--DDDVKKPALQSSVVATSKERTRRDLIQDQ 132
++ +L +++ E+ R+E + + E + +K Q + +E+ RR Q++
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRR---QEE 342
Query: 133 NMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKL----EVQAEEERKQV 188
M EK +++ RR ++ +K ++ + E++++ +E+E+K+ +++ +EE++Q
Sbjct: 343 MMWEK-EEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 401
Query: 189 ENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRM 248
E + RE +E+R +Q E ++ Q+ ++ + +E+ E K+ R + K H
Sbjct: 402 EEKIRE--QEKRQEQ-EAKMWRQEEKIREQEEKIREQEKKMW---RQEEKIH-------- 447
Query: 249 CPATQKLIEESQRKMNALF--EGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAE 306
+K+ EE +R+ + +I E+I + + + Q K+ + V +E+K
Sbjct: 448 --EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMH 505
Query: 307 QEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKM 366
+E K+ ++EE++ + + E E+ E+EEK + E QE+EE+ E E KM
Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQE-EKIREQEEK----IREQEEMMQEQEEKMGEQEEKM 560
Query: 367 EEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELE 426
+E+ ++R E++ Q E++ + E + + I +QE + E ++ E + ++ E
Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620
Query: 427 PEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQ 469
E E + ++ + + +E + + E ++EEK E Q
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKM--WEQEVRLRQQEEKMQEHQ 661
Score = 89.0 bits (219), Expect = 1e-17
Identities = 85/361 (23%), Positives = 172/361 (47%), Gaps = 21/361 (5%)
Query: 156 FKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRE---LFE-ERRAKQTELRLLEQ 211
++QE + E +++ QE E+K+ Q E+ R+Q E RR+ ++E E + ++ E + E+
Sbjct: 303 WRQEEKIQ-EWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK 361
Query: 212 KVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRR 271
+ ++ +L+E E KI + + +K+ E+ +R+ R+
Sbjct: 362 EEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 421
Query: 272 IEFA----EQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEE-----GKVAQREEELEET 322
E E+I + E + RQ K E + +R EE++ EQEE K+ ++EE +
Sbjct: 422 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK 481
Query: 323 GNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKM-EEETEVRESEKQQDS 381
H +I + E+ ++ +H EK +E+EE+ E K+ E+E ++RE E++
Sbjct: 482 EKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIRE 541
Query: 382 QPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSE-----NEASKELEPEMEFEIEPD 436
Q E + + E + + + +QE M + E E E +E E ++ + E
Sbjct: 542 QEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKI 601
Query: 437 KECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQS 496
+E + + +E + E++ E+EEK E + + Q + + +++L+ Q + + +
Sbjct: 602 REQEEMMQEQEE-KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 660
Query: 497 Q 497
Q
Sbjct: 661 Q 661
Score = 81.6 bits (200), Expect = 2e-15
Identities = 98/481 (20%), Positives = 202/481 (41%), Gaps = 44/481 (9%)
Query: 78 DLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEK 137
+LE A+S + +++ +E E D + ++++ + L + + E
Sbjct: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVES 235
Query: 138 GKQRNRRIFGLLMGTLQKFK------QESTVATERQKRRQEIEQKLEVQAEEE----RKQ 187
K + L L++ K Q A K Q + KL+ Q EE R
Sbjct: 236 EKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLN 295
Query: 188 VENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGR 247
+ E + +E + ++ E ++ EQ+ ++ + +E+ E K+ + + + +
Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM------RRQEEMMWEKEE 349
Query: 248 MCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARP------RRQSMKEKEHQVVRNE 301
++++ E + KM L E E E+I ++E + R Q K +E + +R +
Sbjct: 350 KMRRQEEMMWEKEEKMRRL-EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 408
Query: 302 EQKAEQE------EGKVAQREEELEETGNQ--------HNDVEIEEAGEEEEKEIAIVHS 347
E++ EQE E K+ ++EE++ E + H +I E + +E+E
Sbjct: 409 EKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 468
Query: 348 DAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVME 407
+ +EQEE +++E KM E+ ++R+ E++ Q E++ D E + + + QE
Sbjct: 469 EKIREQEEIWRQKE---KMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI 525
Query: 408 TNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESE 467
+ E + E + ++ E E E + ++ + + +E E++ E+EEK E
Sbjct: 526 REQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM---QEQEKMRRQEEKIREQEEKIRE 582
Query: 468 PQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPER 527
Q E + + + + Q + + + ++Q Q E Q QE+ E
Sbjct: 583 -QKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 641
Query: 528 K 528
K
Sbjct: 642 K 642
Score = 75.9 bits (185), Expect = 1e-13
Identities = 104/465 (22%), Positives = 215/465 (46%), Gaps = 41/465 (8%)
Query: 82 AVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQR 141
AV +L GE R +S ++++ S VAT K++ D+ ++E K+R
Sbjct: 152 AVKQLEGEARDLISRLHDSWKFAGELEQAL---SAVATQKKKA------DRYIEELTKER 202
Query: 142 NRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRA 201
+ L T+ E +++ ++++KL++ E E+ +++ +EL +R+
Sbjct: 203 DALSLELYRNTITD--------EELKEKNAKLQEKLQL-VESEKSEIQLNVKEL--KRKL 251
Query: 202 KQTELRLLEQKV--ELAQLQEEWNEHNAKIIKYIR-TKTKPHLFYIPGRMCPATQKLIEE 258
++ +L L +Q++ E L +E +AK+ + + L ++ I+E
Sbjct: 252 ERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQE 311
Query: 259 SQRKMNALFEGRRIEFAEQINKMEARPRRQS--MKEKEHQVVRNEEQKAEQEEGKVAQRE 316
+ K+ E R E E+I + E + RRQ M EKE ++ R EE E+EE K+ + E
Sbjct: 312 WEEKIQEQEEKIR-EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE-KMRRLE 369
Query: 317 EELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESE 376
E + E + E+EE E+EK + E++++EEE+ +E E + E+E ++ E
Sbjct: 370 EMMWE--KEEKIRELEEKMHEQEKI-----REQEEKRQEEEKIREQEKRQEQEAKMWRQE 422
Query: 377 KQQDSQPEEVMDVLEMVENVKHVIADQEVM--ETNRVESVEPSENEASKELEPEMEFEIE 434
++ Q E++ + + + + I +QE + E R E E E + E+ + E
Sbjct: 423 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 482
Query: 435 PDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVL 494
E + + +E V E++ ++EEK E + + Q + + + +++ Q + +
Sbjct: 483 KMHEQEKIRKQEEKV--WRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR 540
Query: 495 QSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTE 539
+ + Q ++ + + + QEQ + + + + K+ E
Sbjct: 541 EQEEMMQEQEEKMGEQE---EKMQEQEKMRRQEEKIREQEEKIRE 582
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 94.0 bits (232), Expect = 4e-19
Identities = 96/442 (21%), Positives = 203/442 (45%), Gaps = 36/442 (8%)
Query: 85 RLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRD---LIQDQNMDEKGKQR 141
RL + + RE Q+ +++ + + Q + +ER R Q++ M E+ + R
Sbjct: 339 RLWEQEKQMREQEQKMRDQEERMWE---QDERLREKEERMREQEKMWEQEEKMQEEERIR 395
Query: 142 NRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQ--VENERRELFEER 199
R +K ++E E++++ Q+ E+ + Q E+E +Q + ++ +L+E+
Sbjct: 396 ERE---------KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE 446
Query: 200 RAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEES 259
+ ++ E ++ EQ+ ++ +E W + + + + ++ +M QK+ ++
Sbjct: 447 KMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQE 506
Query: 260 QRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEEL 319
+R E E++ + E R R Q ++ + +R E++ EQE+ Q E+
Sbjct: 507 ERMW---------EQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMR 557
Query: 320 EETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETE-VRESEKQ 378
EE + + ++ E E ++ + EK +E+EE+ E E KM+E+ E + E E++
Sbjct: 558 EEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK 617
Query: 379 QDSQPEE--VMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPD 436
Q EE + + EM+ + + +QE + E + E E +E E +M+ + E
Sbjct: 618 MWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQE-EKMREQEEKMQGQEEKM 676
Query: 437 KECKSLSPGKENVSALDMEK--ESEEK---EEKESEPQPEPVAQPQPQSQPQLQLQSQSQ 491
+E + G+E EK EEK +E++ Q E + + + + +++ Q +
Sbjct: 677 REQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKE 736
Query: 492 PVLQSQPPSQPEDLSLAVLQPT 513
+Q + P E S L P+
Sbjct: 737 K-MQERLPEHEERCSEPCLPPS 757
Score = 89.7 bits (221), Expect = 8e-18
Identities = 108/520 (20%), Positives = 222/520 (42%), Gaps = 77/520 (14%)
Query: 3 VAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLLLR 62
V TLQE++ + +E L+ ++ IRK + + RL G
Sbjct: 227 VQTNTLQEEMWRQEEELREQEKKIRK----QEEKMWRQEERLREQEG------------- 269
Query: 63 RGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKE 122
K R+ E + R R + + +E + E + KK Q + +E
Sbjct: 270 ------------KMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEE 317
Query: 123 RTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQA- 181
+ + + +EK ++ R++ +QE + + QK R + E+ E
Sbjct: 318 KMWEQEEKMREQEEKMWRQEERLW----------EQEKQMREQEQKMRDQEERMWEQDER 367
Query: 182 --EEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKP 239
E+E + E E+ ++E+ Q E R+ E++ ++ + +E E K+ K +
Sbjct: 368 LREKEERMREQEK--MWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQ 425
Query: 240 HLFYIPGRMCPATQKLI---EESQRKMNALFE-GRRIEFAEQINKMEARP-RRQSMKEKE 294
+ P ++ + E+ Q + ++E +I E++ E + R++ M+E+E
Sbjct: 426 EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQE 485
Query: 295 HQV------VRNEEQKAEQEEGKVAQREEELEE----------TGNQHNDVEIEEAGEEE 338
Q+ +R++EQK +E ++ +++E L E Q + E+ +E+
Sbjct: 486 DQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQ 545
Query: 339 EKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETE-VRESEKQQDSQPEEVMDVLEMVENVK 397
EK+ D E++ EEE+ +E E KM EE E +RE E++ Q E++ + E + +
Sbjct: 546 EKKT----WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE 601
Query: 398 HVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKE 457
+ +QE + E + E E + + EM +E E + ++ + E++
Sbjct: 602 EKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQ-------EQEEKMWEQEEK 654
Query: 458 SEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQ 497
E+EEK E + + Q + + + ++Q Q + + + +
Sbjct: 655 MREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQE 694
Score = 76.6 bits (187), Expect = 7e-14
Identities = 102/426 (23%), Positives = 198/426 (46%), Gaps = 41/426 (9%)
Query: 97 RQESDPEDDDVKKPALQSSVVAT----SKERTRRDLIQDQNMDEKGKQRNRRIFGL-LMG 151
R+E + +D ++ Q + + T S++ R+ +D N+ E R G
Sbjct: 84 RREIEAQDHTIRILTCQKTELETALYYSQDAARK--FEDGNLGESKDLAGRLHHSWHFAG 141
Query: 152 TLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELF-EERRAKQTELRLLE 210
LQ+ S V+T +K + IE E+ E + +E R + EE + K EL +
Sbjct: 142 ELQRAL--SAVSTWHKKADRYIE---ELTKERDALSLELYRNTITNEELKKKNAEL---Q 193
Query: 211 QKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGR 270
+K+ LA+ ++ + N K +K + K F +P T L EE R+ L E
Sbjct: 194 EKLRLAESEKSEIQLNVKELKRKLERAK---FLLPQVQ---TNTLQEEMWRQEEELREQE 247
Query: 271 RIEFAEQINKM---EARPRRQSMKEKEHQV-VRNEEQKAEQEEGKVAQREEELEETGNQH 326
+ + +Q KM E R R Q K +E + +R +E++ ++E ++ ++E+EL E Q
Sbjct: 248 K-KIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELRE---QK 303
Query: 327 NDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKM-EEETEVRESEKQQDSQPEE 385
E EE +E+E++ + EK +E+EE+ E ++ E+E ++RE E++ Q E
Sbjct: 304 KLREQEEQMQEQEEK---MWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360
Query: 386 VMDVLEMVENVKHVIADQEVM-----ETNRVESVEPSENEASKELEPEMEFEIEPDKECK 440
+ + E + + + +QE M + E + E + +E E E E + K+ +
Sbjct: 361 MWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 420
Query: 441 SLSPGKENVSALDMEKESEEK--EEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQP 498
++ +E E +EK E+++ + Q E + + + + + Q ++ Q + + + +
Sbjct: 421 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 480
Query: 499 PSQPED 504
+ ED
Sbjct: 481 MREQED 486
Score = 73.2 bits (178), Expect = 8e-13
Identities = 92/402 (22%), Positives = 181/402 (45%), Gaps = 42/402 (10%)
Query: 131 DQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVEN 190
D+ ++E K+R+ L T+ E +K+ E+++KL + AE E+ +++
Sbjct: 158 DRYIEELTKERDALSLELYRNTITN--------EELKKKNAELQEKLRL-AESEKSEIQL 208
Query: 191 ERRELFEE-RRAK----QTELRLLEQKVELAQLQEEWNEHNAKIIKYIRT--KTKPHLFY 243
+EL + RAK Q + L++ E+ + +EE E KI K + + L
Sbjct: 209 NVKELKRKLERAKFLLPQVQTNTLQE--EMWRQEEELREQEKKIRKQEEKMWRQEERLRE 266
Query: 244 IPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQ 303
G+M +K+ + +R E R E E + + R + + M+E+E ++ EE+
Sbjct: 267 QEGKMREQEEKMRRQEKRLREQEKELREQE-KELREQKKLREQEEQMQEQEEKMWEQEEK 325
Query: 304 KAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEE----------EKEIAIVHSDAEKEQ 353
EQEE K+ ++EE L E Q + E + +EE EKE + + EQ
Sbjct: 326 MREQEE-KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQ 384
Query: 354 EE----EEQKQEMEVKMEEETE-VRESEKQQDSQPEEVMDVLEMVENVKHVIADQE-VME 407
EE EE+ +E E KM EE E +RE E++ Q E + + E + + +E + E
Sbjct: 385 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 444
Query: 408 TNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESE 467
+++ E E +++ + E + K + ++ + E++ ++E+K +
Sbjct: 445 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD 504
Query: 468 ------PQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPE 503
Q E + + + + + Q ++ Q + + + + + E
Sbjct: 505 QEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQE 546
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 93.6 bits (231), Expect = 6e-19
Identities = 94/425 (22%), Positives = 204/425 (48%), Gaps = 37/425 (8%)
Query: 75 KQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNM 134
K RD E + R + E +E + + V+K ++ +E+ RD Q++ M
Sbjct: 391 KMRDQEERMWEQDERLREKEERMREQEKMWEQVEK--MREEKKMQEQEKKTRD--QEEKM 446
Query: 135 DEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQ--VENER 192
E+ + R R +K ++E E++++ Q+ E+ + Q E+E +Q + ++
Sbjct: 447 QEEERIRERE---------KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK 497
Query: 193 RELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPAT 252
+L+E+ + ++ E ++ EQ+ ++ +E W + + + + ++ +M
Sbjct: 498 EKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 557
Query: 253 QKLIEESQR--KMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEG 310
QK+ ++ +R K E + + E++ + E R+ +E +++R +E+K +++E
Sbjct: 558 QKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE 617
Query: 311 KVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEE---EQKQEMEVKME 367
K+ ++EE++ E + + E E+ E+EEK + EK E++ EQK+ K+
Sbjct: 618 KMQEQEEKMWEQEEKMQEQE-EKMWEQEEK----MWEQEEKMWEQQRLPEQKE----KLW 668
Query: 368 EETEVRESEKQQDSQPEEVMDVLEM---VENVKHVIADQEVMETNRVESVEPSENEASKE 424
E +++E EK Q+ Q E++ + +M + + DQE M ES+ E + +E
Sbjct: 669 EHEKMQEQEKMQE-QEEKIWEQEKMEKKTQEQEKKTWDQEKMREE--ESMREREKKMREE 725
Query: 425 LEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQL 484
E E E + ++ + + +E + + E++ E+EEK E Q P + + ++
Sbjct: 726 EEMMREQEEKMQEQEEKMQEQEEEM--WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM 783
Query: 485 QLQSQ 489
Q Q +
Sbjct: 784 QEQEK 788
Score = 90.5 bits (223), Expect = 5e-18
Identities = 107/549 (19%), Positives = 250/549 (45%), Gaps = 40/549 (7%)
Query: 3 VAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLLLR 62
V TLQE++ + +E L+ ++ IRK + ++ + G R + + R
Sbjct: 265 VQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQ------EGKMREQEEKMWR 318
Query: 63 RGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKE 122
+ + R+ E + E R ++E R++ + + +K Q + +E
Sbjct: 319 Q---------EKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEE 369
Query: 123 RTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAE 182
+ R Q++ + E+ KQ + + + ++Q+ + + ++ R++ + +V+
Sbjct: 370 KMWR---QEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKM 426
Query: 183 EERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLF 242
E K+++ + ++ ++ Q E R+ E++ ++ + +E E K+ K +
Sbjct: 427 REEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 486
Query: 243 YIPGRMCPATQKLI---EESQRKMNALFEGR-RIEFAEQINKMEARP-RRQSMKEKEHQV 297
+ P ++ + E+ Q + ++E +I E++ E + R++ M+E+E Q+
Sbjct: 487 EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM 546
Query: 298 ------VRNEEQKA-EQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAE 350
+R++EQK +QEE + +E+ ++T +Q + EE E EK++ +
Sbjct: 547 WEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMR-EEEEMM 605
Query: 351 KEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNR 410
+EQEE+ Q+QE E E+E ++ E E++ Q E++ + E + + + +Q+ + +
Sbjct: 606 REQEEKMQEQE-EKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQK 664
Query: 411 VESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQP 470
+ E + + ++++ + E E +K K ++ D EK EE+ +E E +
Sbjct: 665 EKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQ--EQEKKTWDQEKMREEESMREREKKM 722
Query: 471 EPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDF 530
+ + + ++Q Q + + + Q E + + ++ ++Q LPE+K+
Sbjct: 723 REEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKM----WEQEEKMWEQQ--RLPEQKEK 776
Query: 531 PVESVKLTE 539
E K+ E
Sbjct: 777 LWEHEKMQE 785
Score = 87.0 bits (214), Expect = 5e-17
Identities = 96/474 (20%), Positives = 210/474 (44%), Gaps = 22/474 (4%)
Query: 110 PALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKR 169
P +Q++ + R +L + + K +++ R L K +++ ++KR
Sbjct: 263 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKR 322
Query: 170 RQEIEQKLEVQAEEERKQVE-NERRELFEERRAK--QTELRLLEQKVELAQLQEE-WNEH 225
+E E++L Q +E R+Q E E+ E +E+ K + E ++ EQ+ ++ + +E W +
Sbjct: 323 LREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 382
Query: 226 NAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKM---E 282
+ + + + RM ++L E+ +R ++E + KM E
Sbjct: 383 KQMREQEQKMRDQEE------RMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQE 436
Query: 283 ARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEI 342
+ R Q K +E + +R E+K +EE + ++EE++++ + E +E ++ E
Sbjct: 437 KKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQ 496
Query: 343 AIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIAD 402
+ EK QE+EE+ E E K+ ++ E+ EK+ Q E++ + + + + + D
Sbjct: 497 KEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ-EKMREQEDQMWEQEEKMRD 555
Query: 403 QEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKE 462
QE ++ E +E E K+ + E E ++ + +E +M +E EEK
Sbjct: 556 QEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE---EMMREQEEKM 612
Query: 463 EKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQE--Q 520
+++ E E Q + + + ++Q Q + + + + ++ + Q P+ ++ +
Sbjct: 613 QEQEEKMQE---QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE 669
Query: 521 GHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSR 574
+ E++ + K+ E T E K+ + + R R + K R
Sbjct: 670 HEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMR 723
Score = 80.9 bits (198), Expect = 4e-15
Identities = 89/387 (22%), Positives = 174/387 (44%), Gaps = 36/387 (9%)
Query: 76 QRDLEGAVSRLGGERRTRRES----RQESDPEDDDVKKPALQSSVVATSKERTRRDLIQD 131
Q ++ G ++ + + R + QE D + K + + ++E+ ++ Q+
Sbjct: 523 QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQE 582
Query: 132 QNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAE----EERKQ 187
+ M E+ + R R +K ++E + E++++ QE E+K++ Q E +E K
Sbjct: 583 EKMREEERMRERE---------KKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKM 633
Query: 188 VENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGR 247
E E + +E + + E ++ EQ+ Q ++ W EH K+ + + + + + +
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLW-EHE-KMQEQEKMQEQEEKIWEQEK 691
Query: 248 MCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQ 307
M TQ+ Q K E R E + + + + R + M+E+E ++ EE+ EQ
Sbjct: 692 MEKKTQE-----QEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQ 746
Query: 308 EEGKVAQRE---EELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEV 364
EE Q E E+ E+ Q E +E E EK + EK E+EE+ ++ E
Sbjct: 747 EEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEK-----MQEQEKIWEQEEKMRDQEE 801
Query: 365 KME-EETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVE---PSENE 420
KM +E ++R E++ Q E++ E + + + QE + E +E + E
Sbjct: 802 KMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEE 861
Query: 421 ASKELEPEMEFEIEPDKECKSLSPGKE 447
+E E +M + E +E + G+E
Sbjct: 862 KMREQEEKMRGQEEKMREQEEKMRGQE 888
Score = 79.0 bits (193), Expect = 1e-14
Identities = 100/377 (26%), Positives = 181/377 (48%), Gaps = 39/377 (10%)
Query: 128 LIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQ 187
LI ++ D G+ + F G LQ+ S V+T +K + IE E+ E +
Sbjct: 159 LIPGESKDLAGRLHHSWHFA---GELQRAL--SAVSTRHKKADRYIE---ELTKERDALS 210
Query: 188 VENERRELF-EERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPG 246
+E R + EE + K EL ++K+ LA+ ++ + N K +K + K F +P
Sbjct: 211 LELYRNTITNEELKKKNAEL---QEKLPLAESEKSEIQLNVKELKRKLERAK---FLLPQ 264
Query: 247 RMCPATQKLIEESQRKMNALFEGRRIEFAEQINKM---EARPRRQS--MKEKEHQVVRNE 301
T L EE R+ L E + + +Q KM E R R Q M+E+E ++ R E
Sbjct: 265 VQ---TNTLQEEMWRQEEELREQEK-KIRKQEEKMWRQEERLREQEGKMREQEEKMWRQE 320
Query: 302 EQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQE 361
++ EQE+ ++ ++E+EL E ++ +E +E++E + +EQEE+ +QE
Sbjct: 321 KRLREQEK-ELREQEKELRE----QKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQE 375
Query: 362 MEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVM----ETNRVESVEPS 417
E E+E ++RE E++ Q E + + E + + + +QE M E R E
Sbjct: 376 -ERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQE 434
Query: 418 ENEASKELEPEMEFEIEPDKECKSLSPGKENVSALD--MEKESE---EKEEKESEPQPEP 472
+ + +++ E +M+ E + K + +E + + M+K+ E E+EEKE + Q P
Sbjct: 435 QEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 494
Query: 473 VAQPQPQSQPQLQLQSQ 489
+ + Q ++Q Q +
Sbjct: 495 EQKEKLWEQEKMQEQEE 511
Score = 71.2 bits (173), Expect = 3e-12
Identities = 69/321 (21%), Positives = 150/321 (46%), Gaps = 22/321 (6%)
Query: 75 KQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNM 134
K R+ E R R R++ + + +K Q + +E+ + +
Sbjct: 584 KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQ 643
Query: 135 DEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERR- 193
+EK ++ +++ QK K + Q++ QE E+K+ Q + E+K E E++
Sbjct: 644 EEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKT 703
Query: 194 ----ELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMC 249
++ EE ++ E ++ E++ + + +E+ E K+ + + ++ +M
Sbjct: 704 WDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKM-----QEQEEEMWEQEEKMW 758
Query: 250 PATQKLIEESQ--RKMNALFEGRRIEFAEQINKMEARPRRQSMKEK-EHQVVRNEEQKAE 306
+K+ E+ + + L+E +++ E+I + E + R Q K + + + +R +E+K
Sbjct: 759 EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMR 818
Query: 307 QEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKM 366
+E K+ +EE++ + E + G+EE+ E EK Q +EE+ +E E KM
Sbjct: 819 GQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKME--------EKMQGQEEKMREQEEKM 870
Query: 367 E-EETEVRESEKQQDSQPEEV 386
+E ++RE E++ Q E++
Sbjct: 871 RGQEEKMREQEEKMRGQEEKI 891
Score = 48.5 bits (114), Expect = 2e-05
Identities = 45/243 (18%), Positives = 112/243 (46%), Gaps = 18/243 (7%)
Query: 89 ERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIFGL 148
E+ E QE + + +K Q + ++E+ ++ Q++ +E+ + +
Sbjct: 665 EKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREK---- 720
Query: 149 LMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVEN---ERRELFEERRAKQTE 205
K ++E + E++++ QE E+K++ Q EE +Q E + +++E++R + +
Sbjct: 721 ------KMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQK 774
Query: 206 LRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNA 265
+L E + ++ + ++ W + + + + + ++ + + KM
Sbjct: 775 EKLWEHE-KMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWG 833
Query: 266 LFE---GRRIEFAEQINKMEARPRRQSMKEKEHQV-VRNEEQKAEQEEGKVAQREEELEE 321
E G+ + Q KME + + Q K +E + +R +E+K ++E K+ +EE++
Sbjct: 834 QEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIYC 893
Query: 322 TGN 324
G+
Sbjct: 894 VGS 896
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 90.9 bits (224), Expect = 4e-18
Identities = 125/494 (25%), Positives = 198/494 (40%), Gaps = 59/494 (11%)
Query: 253 QKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKV 312
+ L E +K+ +G++ +K P+R+ + + EE++ E ++ +V
Sbjct: 983 ENLKREHTKKVKEKLKGKK-------DKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQV 1035
Query: 313 AQREEELEETGNQH----NDVEIEEAGEEE---EKEIAIVHSDAEKEQEEEEQKQEMEVK 365
Q +E + + N N ++ E++ EE+ + + V SD ++ +++ +
Sbjct: 1036 TQESKEKKVSENNETIKDNILKTEKSSEEDLSGKHDTVTVSSDLDQFTKDDSKLSISPTA 1095
Query: 366 MEEETEV---RESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEAS 422
+ E V + + ++S P V DVL+ +N++ D+ +VE P N +
Sbjct: 1096 LNTEENVACLQNIQHVEESVPNGVEDVLQTDDNMEICTPDRS--SPAKVEETSPLGN--A 1151
Query: 423 KELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQP 482
+ P++ + K++++ + E ++E SE + Q S
Sbjct: 1152 RLDTPDINIVL------------KQDMATEHPQAEVVKQESSMSESKVLGEVGKQDSSSA 1199
Query: 483 QLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERK--DFPVESVKLTEV 540
L +S + SQ + ++ + Q G+L VE LT V
Sbjct: 1200 SLASAGESTGKKEVAEKSQ-----INLIDKKWKPLQGVGNLAAPNAATSSAVEVKVLTTV 1254
Query: 541 PVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGS 600
P + E KSK K R S KT++ R + SSS T S S S
Sbjct: 1255 PEMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSP 1314
Query: 601 SSSRSSSSSSS---------STSGSSSRDSSSSTSSSSESRSRSRG---RGHNRDRKHRR 648
S SRS S + S S S S SR S+SS S S SRSRSRG RG R R
Sbjct: 1315 SRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSY 1374
Query: 649 SVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESS------RSGKRSS 702
+ R TS RS SS SR + D R RS S+ S RS R S
Sbjct: 1375 RSYKSHR-TSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRS 1433
Query: 703 RSERDRKSDRKDKR 716
RS R SD + R
Sbjct: 1434 RSCRSYGSDSESDR 1447
Score = 65.1 bits (157), Expect = 2e-10
Identities = 78/332 (23%), Positives = 136/332 (40%), Gaps = 37/332 (11%)
Query: 407 ETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEE------ 460
+T + + PS+ E+SK M+ + ++ +S S + S D K ++
Sbjct: 453 QTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLT 512
Query: 461 ---KEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQ----------PEDLSL 507
++ S+ + ++ +S+ + S S+ +S+ S+ P +
Sbjct: 513 HSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTAS 572
Query: 508 AVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRAR 567
+ + P T+ + + ++ V+ V +PV P+ P S+ K + R
Sbjct: 573 QLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYER 632
Query: 568 NKTSKSR-----------SRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGS 616
+ K++ S ++ + SSSS +S S S+ S+ S SS S+ S
Sbjct: 633 IQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRS 692
Query: 617 SSRDSSSSTSSSSESRSRSRGRGHNRDR--KHRRSVDRKRRDTSGLERSHKSSKGGSSRD 674
SR S S + S S +RSRS H+R R R K D S RS S SS D
Sbjct: 693 RSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRS-SSYTSISSDD 751
Query: 675 TKGSKDKNSRSDRKRSISESSRSGKRSSRSER 706
+ +K + S +K S+S K SS SE+
Sbjct: 752 GRRAKRRLRSSGKKNSVSHK----KHSSSSEK 779
Score = 63.5 bits (153), Expect = 6e-10
Identities = 78/305 (25%), Positives = 125/305 (40%), Gaps = 33/305 (10%)
Query: 441 SLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPV--LQSQP 498
S S ++ S + S+ E K + +P Q ++ + +++ PV L P
Sbjct: 555 SKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSP 614
Query: 499 PSQPEDLSLAVLQPTPQVTQEQG----HLLPERKDFPVESVKLT---------EVPVEPV 545
P +P+ + QE HLLP + + + ++K T E E
Sbjct: 615 PPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESD 674
Query: 546 LTVHPE-----SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGS 600
+ + + S+S ++RSRS S +RSRS +SS S S S SS S S +
Sbjct: 675 QSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSD 734
Query: 601 SSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGL 660
S S SSS +S S R + SS + S S + + K S K RD S
Sbjct: 735 HSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSC 794
Query: 661 ERSHKSSKGG--SSRDTKGS----------KDKNSRSDRKRSISESSRSGKRSSRSERDR 708
R + S+ S D++ S K+K + +R + E +R G+ S+SER+
Sbjct: 795 VRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNR-GEEKSKSEREC 853
Query: 709 KSDRK 713
+K
Sbjct: 854 PHSKK 858
Score = 61.6 bits (148), Expect = 2e-09
Identities = 97/453 (21%), Positives = 172/453 (37%), Gaps = 51/453 (11%)
Query: 246 GRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKA 305
G + + K + E +RK EG ++ + + S E EH+ R + K
Sbjct: 174 GVLATKSIKDVFEKKRKKPTHSEG-----SDSSSNSSSSSESSSESELEHERSRRRKHKR 228
Query: 306 EQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVK 365
+ + +R +E + N + G E + ++ ++ + ++++ V+
Sbjct: 229 RPKVKRSKKRRKEASSSEEPRNKHAMNPKGHSERSD-----TNEKRSVDSSAKREKPVVR 283
Query: 366 MEEETEVRESE-KQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKE 424
EE V E+ + P + + +V +++DQ+ PS +++ ++
Sbjct: 284 PEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQK-----------PSVSKSGRK 332
Query: 425 LEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKES--EPQPEPVAQPQPQSQP 482
++ +S S ++ S+ EE + + P E ++ S P
Sbjct: 333 IKGRGTIRYHTPPRSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDP 392
Query: 483 ---QLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKL-- 537
+ +S SQ DLS A + GH RK+ V+ K
Sbjct: 393 CSSRWDERSLSQRSRSWSYNGYYSDLSTA---------RHSGHHKKRRKEKKVKHKKKGK 443
Query: 538 --------TEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTS 589
+ +L SK+ TR R ++S+S S SS SS S S
Sbjct: 444 KQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKS 503
Query: 590 SSSGSSSSSGSS--SSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHR 647
SS + SS S RS S S S + GSS S +++ SSS SRSRS+ R ++ HR
Sbjct: 504 DKDVQSSLTHSSRDSYRSKSHSQSYSRGSSR--SRTASKSSSHSRSRSKSRSSSKS-GHR 560
Query: 648 RSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKD 680
+ + R T+ +K K R T +
Sbjct: 561 KRASKSPRKTASQLSENKPVKTEPLRATMAQNE 593
Score = 58.5 bits (140), Expect = 2e-08
Identities = 47/160 (29%), Positives = 73/160 (45%), Gaps = 10/160 (6%)
Query: 552 SKSKTKTRSR----SRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSS 607
S S++ TRSR S R+R+ +S+S SR+ S S S +SS + SS G + R
Sbjct: 701 SYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLR 760
Query: 608 SSSSSTSGSSSRDSSSS--TSSSSESRSRSRGRGHNRDRKHRRSV----DRKRRDTSGLE 661
SS S S + SSSS T S + R R + + R S+ D ++ +
Sbjct: 761 SSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQ 820
Query: 662 RSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRS 701
+ + K G T ++KN ++ +S E S KR+
Sbjct: 821 SAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRT 860
Score = 53.9 bits (128), Expect = 5e-07
Identities = 93/372 (25%), Positives = 140/372 (37%), Gaps = 68/372 (18%)
Query: 394 ENVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALD 453
+++K V + T+ S S + +S E E E E E + K K S
Sbjct: 179 KSIKDVFEKKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRS--- 235
Query: 454 MEKESEEKEEKESEPQPEPVAQPQPQSQPQ--LQLQSQSQPVLQSQPPSQPEDLSLAVLQ 511
K+ ++ EP+ + P+ S+ + +S + +P +PE++
Sbjct: 236 --KKRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIP----- 288
Query: 512 PTPQVTQEQGHLLPERKDFPVESVKLT-EVP-VEPVLTVHPESKSKTKTRSRSRGRARNK 569
P P E LL R+D PV + + ++P V P+++ S SK+ + + RG R
Sbjct: 289 PVP----ENRFLL--RRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYH 342
Query: 570 TSKSRSRSSSSSSSSSSSTSSS---------------SGSSSSSGSSSSRSSSSSSSSTS 614
T RSRS S S SS + SG S G S SS S
Sbjct: 343 TPP-RSRSCSESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERS 401
Query: 615 GSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLE-RSHKSSKG---- 669
S R S S + S +R GH++ R+ + V K++ R HK +K
Sbjct: 402 -LSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRIL 460
Query: 670 ---------GSSRDTKGSKDKNSRSDRKRSISESSRSGKR---------------SSRSE 705
S+R K S D+ RS R S+S S S KR SSR
Sbjct: 461 IPSDIESSKSSTRRMKSSCDRE-RSSRSSSLS-SHHSSKRDWSKSDKDVQSSLTHSSRDS 518
Query: 706 RDRKSDRKDKRR 717
KS + R
Sbjct: 519 YRSKSHSQSYSR 530
Score = 50.8 bits (120), Expect = 4e-06
Identities = 47/171 (27%), Positives = 72/171 (42%), Gaps = 8/171 (4%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSG---SSSSRSSSS 608
S S T S RA+ + S ++S S SSS+ + S G SS R S
Sbjct: 741 SSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSE 800
Query: 609 SSSSTSGSSSRDSSSSTSSSSESRSRSRG---RGHNRDRKHRRSVDRK--RRDTSGLERS 663
S SS SS + SS ++ S +G R HN+ K+R K R +R+
Sbjct: 801 SRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRT 860
Query: 664 HKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
K + R+ K KN + S S S R ++S+++ SD+++
Sbjct: 861 LKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEE 911
Score = 40.8 bits (94), Expect = 0.004
Identities = 132/638 (20%), Positives = 229/638 (35%), Gaps = 113/638 (17%)
Query: 61 LRRGFSDS-GGGPPAKQRDLEGAV--SRLGGERRTRRESRQESDPEDDDVKKPALQSS-- 115
L+ SD G K+++ G+ S ER + S+ +S P D + A S
Sbjct: 861 LKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSES 920
Query: 116 --------VVATSKERTRRDLIQDQNMDEKGKQR--------------NRRIFGLLMGTL 153
V T+K T L D + KQR N R G
Sbjct: 921 EVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNR------GKP 974
Query: 154 QKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKV 213
QK K S E KR + K +++ ++++K +R++ F Q L E++
Sbjct: 975 QKHKHGSK---ENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHW----QPPLEFGEEEE 1027
Query: 214 ELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEE--SQRKMNALFEGRR 271
E ++ E K + K ++ T+K EE S +
Sbjct: 1028 EEIDDKQVTQESKEKKVSENNETIKDNIL--------KTEKSSEEDLSGKHDTVTVSSDL 1079
Query: 272 IEFAEQINKMEARPRRQSMKEKEH--QVVRNEEQKAEQEEGKVAQREEELEE-TGNQHND 328
+F + +K+ P + +E Q +++ E+ V Q ++ +E T ++ +
Sbjct: 1080 DQFTKDDSKLSISPTALNTEENVACLQNIQHVEESVPNGVEDVLQTDDNMEICTPDRSSP 1139
Query: 329 VEIEEAG-------EEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDS 381
++EE + + I + A + + E KQE M E + E KQ S
Sbjct: 1140 AKVEETSPLGNARLDTPDINIVLKQDMATEHPQAEVVKQESS--MSESKVLGEVGKQDSS 1197
Query: 382 QPE-----EVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELE-------PEM 429
E E+ E + + D++ V ++ S +E PEM
Sbjct: 1198 SASLASAGESTGKKEVAEKSQINLIDKKWKPLQGVGNLAAPNAATSSAVEVKVLTTVPEM 1257
Query: 430 E-----FEIEPDKECK--SLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQP 482
+ EI+ + + SL + L+ ++E E P + +Q + S+
Sbjct: 1258 KPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRS 1317
Query: 483 QLQLQSQSQ----PVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLT 538
+ + +++S+ V S S+ + + + ++ +G R S +
Sbjct: 1318 RSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSY 1377
Query: 539 EVPVEPVLTVHPESKSKTKTRSRSRG-------RARNKT-----SKSRSRSSSSSSSS-- 584
+ +T +RSRSR R+R+ T S+SRSRS S S S
Sbjct: 1378 K-------------SHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYH 1424
Query: 585 -SSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDS 621
S + S S S GS S S S + SSR S
Sbjct: 1425 RGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESSRYS 1462
Score = 30.4 bits (67), Expect = 6.0
Identities = 29/139 (20%), Positives = 49/139 (35%), Gaps = 16/139 (11%)
Query: 515 QVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSR 574
+V ++ +L + P V++ + V ++ + K K + S G + S S
Sbjct: 148 EVIEQIENLKTDAASRPYADVRVIDCGVLATKSIKDVFEKKRKKPTHSEGSDSSSNSSSS 207
Query: 575 SRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSR 634
S SSS S S R S R +S+S ++
Sbjct: 208 SESSSESELEH--------------ERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHA 253
Query: 635 SRGRGHNR--DRKHRRSVD 651
+GH+ D +RSVD
Sbjct: 254 MNPKGHSERSDTNEKRSVD 272
>gi|169166609 PREDICTED: similar to ribonucleic acid binding protein
S1 isoform 6 [Homo sapiens]
Length = 305
Score = 90.1 bits (222), Expect = 6e-18
Identities = 61/121 (50%), Positives = 73/121 (60%), Gaps = 9/121 (7%)
Query: 552 SKSKTKTRSRSRG---------RARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSS 602
S K+K RS+ +G R R+KT K RS SS SSS+ S S+S+SS SS+S SS
Sbjct: 35 SDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSS 94
Query: 603 SRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLER 662
S SSSSS+SS SGSSS SSS+SSSS S S SR R NR R +S KR + R
Sbjct: 95 SGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRR 154
Query: 663 S 663
S
Sbjct: 155 S 155
Score = 78.6 bits (192), Expect = 2e-14
Identities = 55/114 (48%), Positives = 70/114 (61%), Gaps = 7/114 (6%)
Query: 547 TVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSS-SSSSTSSSSGSSSSSGSSSSRS 605
T K + + ++R R A + +S +RSRSSS+SSS SS+ST SSSGSSSSS SS S S
Sbjct: 49 TKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGS 108
Query: 606 SSSS-SSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTS 658
SS+S SSS+S SS S S + RSRS+ + RD K +RKRR S
Sbjct: 109 SSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEK-----ERKRRSPS 157
Score = 62.4 bits (150), Expect = 1e-09
Identities = 51/154 (33%), Positives = 71/154 (46%), Gaps = 13/154 (8%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
S +K K RS + + R+K K ++ SS T +SS S S+ SRSSS+SSS
Sbjct: 27 SPTKRKDRSDEKSKDRSK-DKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSS 85
Query: 612 -------STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTS-----G 659
S+SGSSS +SS + SSS SRS S RR D +RR S
Sbjct: 86 GSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPK 145
Query: 660 LERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISE 693
+ + + S + TK + +R+ K I E
Sbjct: 146 RDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIME 179
Score = 58.9 bits (141), Expect = 2e-08
Identities = 51/157 (32%), Positives = 71/157 (45%), Gaps = 32/157 (20%)
Query: 554 SKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSST 613
S TK + RS +++++ SK + + SS + S+SSGSSS+RS SSS+SS+
Sbjct: 27 SPTKRKDRSDEKSKDR-SKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSS 85
Query: 614 SGSSSRDSSS-STSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSS 672
S+S SSS S+SSS+ SRS S S RS SS S
Sbjct: 86 GSSTSTGSSSGSSSSSASSRSGS----------------------SSTSRSSSSSSSSGS 123
Query: 673 RDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRK 709
+ N R R +S K R E++RK
Sbjct: 124 PSPSRRRHDNRRRSRSKS--------KPPKRDEKERK 152
Score = 49.7 bits (117), Expect = 9e-06
Identities = 45/137 (32%), Positives = 58/137 (42%), Gaps = 8/137 (5%)
Query: 584 SSSSTSSSSGSSSSSGSSSSRSSSSSS-SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNR 642
S S G ++ SS+R+ S + S S+D S ++ ES + RGR R
Sbjct: 4 SGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTR 63
Query: 643 DRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISES-SRSGKRS 701
R+ S R RS +S GSS T S +S S RS S S SRS S
Sbjct: 64 KRRSASSGSSSTR-----SRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS 118
Query: 702 SRSERDRKSDRK-DKRR 717
S S S R+ D RR
Sbjct: 119 SSSGSPSPSRRRHDNRR 135
Score = 47.0 bits (110), Expect = 6e-05
Identities = 42/152 (27%), Positives = 64/152 (42%), Gaps = 14/152 (9%)
Query: 567 RNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTS 626
+ KS +R+ S + S S S G++ + SS + R S+SS S
Sbjct: 15 KENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGAT--KESSEKDRGRDKTRKRRSASSGS 72
Query: 627 SSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSD 686
SS+ SRS S + +SG S SS+ GSS ++ S +S S
Sbjct: 73 SSTRSRSSSTSSSGS---------STSTGSSSGSSSSSASSRSGSSSTSRSS--SSSSSS 121
Query: 687 RKRSISESSRSGKRSSRSE-RDRKSDRKDKRR 717
S S +R SRS+ + K D K+++R
Sbjct: 122 GSPSPSRRRHDNRRRSRSKSKPPKRDEKERKR 153
Score = 33.9 bits (76), Expect = 0.54
Identities = 28/80 (35%), Positives = 38/80 (47%), Gaps = 7/80 (8%)
Query: 503 EDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRS 562
E + VL P P+ T + P R+ P + L P + P +S + RSRS
Sbjct: 232 EITATVVLAPWPRPTPRR--FSPPRRMLPPPPMWLRSPPRMRRRSRSPRRRSPVRRRSRS 289
Query: 563 RGRARNKTSKSRSRSSSSSS 582
GR R+ RSRSSS+SS
Sbjct: 290 PGRRRH-----RSRSSSNSS 304
>gi|113415994 PREDICTED: similar to ribonucleic acid binding protein
S1 isoform 2 [Homo sapiens]
Length = 305
Score = 90.1 bits (222), Expect = 6e-18
Identities = 61/121 (50%), Positives = 73/121 (60%), Gaps = 9/121 (7%)
Query: 552 SKSKTKTRSRSRG---------RARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSS 602
S K+K RS+ +G R R+KT K RS SS SSS+ S S+S+SS SS+S SS
Sbjct: 35 SDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSS 94
Query: 603 SRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLER 662
S SSSSS+SS SGSSS SSS+SSSS S S SR R NR R +S KR + R
Sbjct: 95 SGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRR 154
Query: 663 S 663
S
Sbjct: 155 S 155
Score = 78.6 bits (192), Expect = 2e-14
Identities = 55/114 (48%), Positives = 70/114 (61%), Gaps = 7/114 (6%)
Query: 547 TVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSS-SSSSTSSSSGSSSSSGSSSSRS 605
T K + + ++R R A + +S +RSRSSS+SSS SS+ST SSSGSSSSS SS S S
Sbjct: 49 TKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGS 108
Query: 606 SSSS-SSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTS 658
SS+S SSS+S SS S S + RSRS+ + RD K +RKRR S
Sbjct: 109 SSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEK-----ERKRRSPS 157
Score = 62.4 bits (150), Expect = 1e-09
Identities = 51/154 (33%), Positives = 71/154 (46%), Gaps = 13/154 (8%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
S +K K RS + + R+K K ++ SS T +SS S S+ SRSSS+SSS
Sbjct: 27 SPTKRKDRSDEKSKDRSK-DKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSS 85
Query: 612 -------STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTS-----G 659
S+SGSSS +SS + SSS SRS S RR D +RR S
Sbjct: 86 GSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPK 145
Query: 660 LERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISE 693
+ + + S + TK + +R+ K I E
Sbjct: 146 RDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIME 179
Score = 58.9 bits (141), Expect = 2e-08
Identities = 51/157 (32%), Positives = 71/157 (45%), Gaps = 32/157 (20%)
Query: 554 SKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSST 613
S TK + RS +++++ SK + + SS + S+SSGSSS+RS SSS+SS+
Sbjct: 27 SPTKRKDRSDEKSKDR-SKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSS 85
Query: 614 SGSSSRDSSS-STSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSS 672
S+S SSS S+SSS+ SRS S S RS SS S
Sbjct: 86 GSSTSTGSSSGSSSSSASSRSGS----------------------SSTSRSSSSSSSSGS 123
Query: 673 RDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRK 709
+ N R R +S K R E++RK
Sbjct: 124 PSPSRRRHDNRRRSRSKS--------KPPKRDEKERK 152
Score = 49.7 bits (117), Expect = 9e-06
Identities = 45/137 (32%), Positives = 58/137 (42%), Gaps = 8/137 (5%)
Query: 584 SSSSTSSSSGSSSSSGSSSSRSSSSSS-SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNR 642
S S G ++ SS+R+ S + S S+D S ++ ES + RGR R
Sbjct: 4 SGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTR 63
Query: 643 DRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISES-SRSGKRS 701
R+ S R RS +S GSS T S +S S RS S S SRS S
Sbjct: 64 KRRSASSGSSSTR-----SRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS 118
Query: 702 SRSERDRKSDRK-DKRR 717
S S S R+ D RR
Sbjct: 119 SSSGSPSPSRRRHDNRR 135
Score = 47.0 bits (110), Expect = 6e-05
Identities = 42/152 (27%), Positives = 64/152 (42%), Gaps = 14/152 (9%)
Query: 567 RNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTS 626
+ KS +R+ S + S S S G++ + SS + R S+SS S
Sbjct: 15 KENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGAT--KESSEKDRGRDKTRKRRSASSGS 72
Query: 627 SSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSD 686
SS+ SRS S + +SG S SS+ GSS ++ S +S S
Sbjct: 73 SSTRSRSSSTSSSGS---------STSTGSSSGSSSSSASSRSGSSSTSRSS--SSSSSS 121
Query: 687 RKRSISESSRSGKRSSRSE-RDRKSDRKDKRR 717
S S +R SRS+ + K D K+++R
Sbjct: 122 GSPSPSRRRHDNRRRSRSKSKPPKRDEKERKR 153
Score = 33.9 bits (76), Expect = 0.54
Identities = 28/80 (35%), Positives = 38/80 (47%), Gaps = 7/80 (8%)
Query: 503 EDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRS 562
E + VL P P+ T + P R+ P + L P + P +S + RSRS
Sbjct: 232 EITATVVLAPWPRPTPRR--FSPPRRMLPPPPMWLRSPPRMRRRSRSPRRRSPVRRRSRS 289
Query: 563 RGRARNKTSKSRSRSSSSSS 582
GR R+ RSRSSS+SS
Sbjct: 290 PGRRRH-----RSRSSSNSS 304
>gi|6857826 RNA-binding protein S1, serine-rich domain [Homo
sapiens]
Length = 305
Score = 90.1 bits (222), Expect = 6e-18
Identities = 61/121 (50%), Positives = 73/121 (60%), Gaps = 9/121 (7%)
Query: 552 SKSKTKTRSRSRG---------RARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSS 602
S K+K RS+ +G R R+KT K RS SS SSS+ S S+S+SS SS+S SS
Sbjct: 35 SDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSS 94
Query: 603 SRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLER 662
S SSSSS+SS SGSSS SSS+SSSS S S SR R NR R +S KR + R
Sbjct: 95 SGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRR 154
Query: 663 S 663
S
Sbjct: 155 S 155
Score = 78.6 bits (192), Expect = 2e-14
Identities = 55/114 (48%), Positives = 70/114 (61%), Gaps = 7/114 (6%)
Query: 547 TVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSS-SSSSTSSSSGSSSSSGSSSSRS 605
T K + + ++R R A + +S +RSRSSS+SSS SS+ST SSSGSSSSS SS S S
Sbjct: 49 TKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGS 108
Query: 606 SSSS-SSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTS 658
SS+S SSS+S SS S S + RSRS+ + RD K +RKRR S
Sbjct: 109 SSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEK-----ERKRRSPS 157
Score = 62.4 bits (150), Expect = 1e-09
Identities = 51/154 (33%), Positives = 71/154 (46%), Gaps = 13/154 (8%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
S +K K RS + + R+K K ++ SS T +SS S S+ SRSSS+SSS
Sbjct: 27 SPTKRKDRSDEKSKDRSK-DKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSS 85
Query: 612 -------STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTS-----G 659
S+SGSSS +SS + SSS SRS S RR D +RR S
Sbjct: 86 GSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPK 145
Query: 660 LERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISE 693
+ + + S + TK + +R+ K I E
Sbjct: 146 RDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIME 179
Score = 58.9 bits (141), Expect = 2e-08
Identities = 51/157 (32%), Positives = 71/157 (45%), Gaps = 32/157 (20%)
Query: 554 SKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSST 613
S TK + RS +++++ SK + + SS + S+SSGSSS+RS SSS+SS+
Sbjct: 27 SPTKRKDRSDEKSKDR-SKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSS 85
Query: 614 SGSSSRDSSS-STSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSS 672
S+S SSS S+SSS+ SRS S S RS SS S
Sbjct: 86 GSSTSTGSSSGSSSSSASSRSGS----------------------SSTSRSSSSSSSSGS 123
Query: 673 RDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRK 709
+ N R R +S K R E++RK
Sbjct: 124 PSPSRRRHDNRRRSRSKS--------KPPKRDEKERK 152
Score = 49.7 bits (117), Expect = 9e-06
Identities = 45/137 (32%), Positives = 58/137 (42%), Gaps = 8/137 (5%)
Query: 584 SSSSTSSSSGSSSSSGSSSSRSSSSSS-SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNR 642
S S G ++ SS+R+ S + S S+D S ++ ES + RGR R
Sbjct: 4 SGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTR 63
Query: 643 DRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISES-SRSGKRS 701
R+ S R RS +S GSS T S +S S RS S S SRS S
Sbjct: 64 KRRSASSGSSSTR-----SRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS 118
Query: 702 SRSERDRKSDRK-DKRR 717
S S S R+ D RR
Sbjct: 119 SSSGSPSPSRRRHDNRR 135
Score = 47.0 bits (110), Expect = 6e-05
Identities = 42/152 (27%), Positives = 64/152 (42%), Gaps = 14/152 (9%)
Query: 567 RNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTS 626
+ KS +R+ S + S S S G++ + SS + R S+SS S
Sbjct: 15 KENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGAT--KESSEKDRGRDKTRKRRSASSGS 72
Query: 627 SSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSD 686
SS+ SRS S + +SG S SS+ GSS ++ S +S S
Sbjct: 73 SSTRSRSSSTSSSGS---------STSTGSSSGSSSSSASSRSGSSSTSRSS--SSSSSS 121
Query: 687 RKRSISESSRSGKRSSRSE-RDRKSDRKDKRR 717
S S +R SRS+ + K D K+++R
Sbjct: 122 GSPSPSRRRHDNRRRSRSKSKPPKRDEKERKR 153
>gi|18379334 RNA-binding protein S1, serine-rich domain [Homo
sapiens]
Length = 305
Score = 90.1 bits (222), Expect = 6e-18
Identities = 61/121 (50%), Positives = 73/121 (60%), Gaps = 9/121 (7%)
Query: 552 SKSKTKTRSRSRG---------RARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSS 602
S K+K RS+ +G R R+KT K RS SS SSS+ S S+S+SS SS+S SS
Sbjct: 35 SDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSS 94
Query: 603 SRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLER 662
S SSSSS+SS SGSSS SSS+SSSS S S SR R NR R +S KR + R
Sbjct: 95 SGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRR 154
Query: 663 S 663
S
Sbjct: 155 S 155
Score = 78.6 bits (192), Expect = 2e-14
Identities = 55/114 (48%), Positives = 70/114 (61%), Gaps = 7/114 (6%)
Query: 547 TVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSS-SSSSTSSSSGSSSSSGSSSSRS 605
T K + + ++R R A + +S +RSRSSS+SSS SS+ST SSSGSSSSS SS S S
Sbjct: 49 TKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGS 108
Query: 606 SSSS-SSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTS 658
SS+S SSS+S SS S S + RSRS+ + RD K +RKRR S
Sbjct: 109 SSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEK-----ERKRRSPS 157
Score = 62.4 bits (150), Expect = 1e-09
Identities = 51/154 (33%), Positives = 71/154 (46%), Gaps = 13/154 (8%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
S +K K RS + + R+K K ++ SS T +SS S S+ SRSSS+SSS
Sbjct: 27 SPTKRKDRSDEKSKDRSK-DKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSS 85
Query: 612 -------STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTS-----G 659
S+SGSSS +SS + SSS SRS S RR D +RR S
Sbjct: 86 GSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPK 145
Query: 660 LERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISE 693
+ + + S + TK + +R+ K I E
Sbjct: 146 RDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIME 179
Score = 58.9 bits (141), Expect = 2e-08
Identities = 51/157 (32%), Positives = 71/157 (45%), Gaps = 32/157 (20%)
Query: 554 SKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSST 613
S TK + RS +++++ SK + + SS + S+SSGSSS+RS SSS+SS+
Sbjct: 27 SPTKRKDRSDEKSKDR-SKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSS 85
Query: 614 SGSSSRDSSS-STSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSS 672
S+S SSS S+SSS+ SRS S S RS SS S
Sbjct: 86 GSSTSTGSSSGSSSSSASSRSGS----------------------SSTSRSSSSSSSSGS 123
Query: 673 RDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRK 709
+ N R R +S K R E++RK
Sbjct: 124 PSPSRRRHDNRRRSRSKS--------KPPKRDEKERK 152
Score = 49.7 bits (117), Expect = 9e-06
Identities = 45/137 (32%), Positives = 58/137 (42%), Gaps = 8/137 (5%)
Query: 584 SSSSTSSSSGSSSSSGSSSSRSSSSSS-SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNR 642
S S G ++ SS+R+ S + S S+D S ++ ES + RGR R
Sbjct: 4 SGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTR 63
Query: 643 DRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISES-SRSGKRS 701
R+ S R RS +S GSS T S +S S RS S S SRS S
Sbjct: 64 KRRSASSGSSSTR-----SRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS 118
Query: 702 SRSERDRKSDRK-DKRR 717
S S S R+ D RR
Sbjct: 119 SSSGSPSPSRRRHDNRR 135
Score = 47.0 bits (110), Expect = 6e-05
Identities = 42/152 (27%), Positives = 64/152 (42%), Gaps = 14/152 (9%)
Query: 567 RNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTS 626
+ KS +R+ S + S S S G++ + SS + R S+SS S
Sbjct: 15 KENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGAT--KESSEKDRGRDKTRKRRSASSGS 72
Query: 627 SSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSD 686
SS+ SRS S + +SG S SS+ GSS ++ S +S S
Sbjct: 73 SSTRSRSSSTSSSGS---------STSTGSSSGSSSSSASSRSGSSSTSRSS--SSSSSS 121
Query: 687 RKRSISESSRSGKRSSRSE-RDRKSDRKDKRR 717
S S +R SRS+ + K D K+++R
Sbjct: 122 GSPSPSRRRHDNRRRSRSKSKPPKRDEKERKR 153
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 89.7 bits (221), Expect = 8e-18
Identities = 124/581 (21%), Positives = 234/581 (40%), Gaps = 60/581 (10%)
Query: 64 GFSDSGGGPPAKQRDLEGAVSRLGGE----RRTRRESRQESDPEDDDVKKPALQSSVVAT 119
G SD G A + + E G E +E+ E+ PE +DV+ P +
Sbjct: 1827 GQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPE 1886
Query: 120 SKERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLE- 178
S++ + + + +G + +K Q T + E + E E + E
Sbjct: 1887 SEDVETPEAEWEVQPESEGAEAPE---------AEKEAQPETESVEALETEGEDEPESEG 1937
Query: 179 ---VQAEEERKQVENERR---ELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKY 232
+AEE ++ E + + E+ E + A++ E + + VE +++ E E +
Sbjct: 1938 AEAQEAEEAAQEAEGQTQPESEVIESQEAEE-EAQPESEDVEALEVEVETQEAEGEAQPE 1996
Query: 233 IRTKTKPHLFYIPGRMCPATQKLIEESQ----RKMNALFEGRRIEFAEQINKMEARPRRQ 288
P G M A ++ ES + + E + +E Q + +A+P
Sbjct: 1997 SEDVEAPE---AEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESD 2053
Query: 289 SMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSD 348
++ E E++A++ EG+V + E E + E E + E + + ++
Sbjct: 2054 GVEAPE------AEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAE 2107
Query: 349 AEKEQEEEEQKQEMEVKMEEETE-VRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVME 407
E ++ E + E E + + E+E + E + ++QPE E V+ A+ E
Sbjct: 2108 GEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPES--------EGVEAQDAEGEA-- 2157
Query: 408 TNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESE 467
+ ES EA +E +PE+E P+ E ++ P E + A + E E++ + E
Sbjct: 2158 --QPESEGIEAQEAEEEAQPELEGVEAPEAEGEA-QPESEGIEAPEAEGEAQPELEGVEA 2214
Query: 468 PQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHL-LPE 526
P+ E AQP+P+ + + ++QP +S+ +Q E + +PQV+ G
Sbjct: 2215 PEAEEEAQPEPEGVETPEAEGEAQP--ESEGETQGEK------KGSPQVSLGDGQSEEAS 2266
Query: 527 RKDFPVESVKLTEVPVEPVLTVHPESKSKT---KTRSRSRGRARNKTSKSRSRSSSSSSS 583
PV + T P T H S+T +R+ S G K S++ + S
Sbjct: 2267 ESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSP 2326
Query: 584 SSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSS 624
+ ST + ++ S+S + GS + + +S
Sbjct: 2327 DAKSTGTPHAERKATRMYPESSTSEQEEAPLGSRTPEQGAS 2367
Score = 75.1 bits (183), Expect = 2e-13
Identities = 73/359 (20%), Positives = 149/359 (41%), Gaps = 23/359 (6%)
Query: 282 EARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKE 341
EA+P + ++ E + E + Q E + + E E + DVE EA E + E
Sbjct: 1843 EAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPE 1902
Query: 342 IAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIA 401
AE + E+E + E E ETE + + + ++ +E + + E
Sbjct: 1903 ----SEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEG--QTQP 1956
Query: 402 DQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEK 461
+ EV+E+ E E+E + LE E+E + E + E + P E+V A + E E +E
Sbjct: 1957 ESEVIESQEAEEEAQPESEDVEALEVEVETQ-EAEGEAQ---PESEDVEAPEAEGEMQEA 2012
Query: 462 EEKESEPQPEPV-AQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQ 520
EE E++P+ + V AQP+ + + +++ ++Q +++ +QPE + + + + +
Sbjct: 2013 EE-EAQPESDGVEAQPKSEGEEAQEVEGETQ---KTEGDAQPESDGVEAPEAEEEAQEAE 2068
Query: 521 GHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSS 580
G + + ES E V E +++ ++ A + K+ +
Sbjct: 2069 GEVQEAEGEAHPES--------EDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPE 2120
Query: 581 SSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRG 639
+ + S + + G + S + G + +S + +E ++ G
Sbjct: 2121 TEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEG 2179
Score = 73.6 bits (179), Expect = 6e-13
Identities = 97/459 (21%), Positives = 154/459 (33%), Gaps = 64/459 (13%)
Query: 268 EGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHN 327
EG +E + EA Q E +E + E E + + E E E
Sbjct: 1880 EGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAE 1939
Query: 328 DVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVM 387
E EEA +E E + E ++ EEE + E E E EV E + ++QPE
Sbjct: 1940 AQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESED 1999
Query: 388 DVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELE--------------------- 426
E ++ E++ VE+ SE E ++E+E
Sbjct: 2000 VEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPE 2059
Query: 427 ------------PEMEFEIEPDKEC-------KSLSPGKENVSALDMEKESEEKE----- 462
E E E P+ E P E V A + E E+++ E
Sbjct: 2060 AEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAP 2119
Query: 463 EKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQE--- 519
E E E QPE P+++ + Q +S+ ++ +QPE + + + E
Sbjct: 2120 ETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEG 2179
Query: 520 ------QGHLLPERKDFPVESVKLTEVP-VEPVLTVHPESKSKTKTRSRSRGRARNKTSK 572
+G PE + + P +E V E +++ + A +
Sbjct: 2180 VEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQP 2239
Query: 573 SRSRSSSSSSSSSSSTSSSSGSSSSSGSSSS---RSSSSSSSSTSGSSSRDSSSSTSSSS 629
+ S S G S + SSS + S G + S + S
Sbjct: 2240 ESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPS 2299
Query: 630 ESRSRSRGRGHNRDRKH------RRSVDRKRRDTSGLER 662
SR+ S G +D ++ RS D K T ER
Sbjct: 2300 SSRASSWGNCWQKDSENDHVLGDTRSPDAKSTGTPHAER 2338
Score = 73.2 bits (178), Expect = 8e-13
Identities = 89/424 (20%), Positives = 170/424 (40%), Gaps = 44/424 (10%)
Query: 285 PRRQSMKEKEHQVVRNEEQKAE-QEEGKVAQREEELEETGNQHNDVE-IEEAGEEEEKEI 342
P + + E + V E + E Q E + A+ E +E + VE +E GE+E +
Sbjct: 1877 PEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPE-- 1934
Query: 343 AIVHSDAEKEQEEEEQKQEMEVKMEEETEVRES-EKQQDSQPEEVMDVLEMVENVKHVIA 401
S+ + QE EE QE E + + E+EV ES E ++++QPE E VE ++ +
Sbjct: 1935 ----SEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPES-----EDVEALEVEVE 1985
Query: 402 DQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEK 461
QE + ES + EA E++ E E E +P+ + P E A ++E E+ +K
Sbjct: 1986 TQEAEGEAQPESEDVEAPEAEGEMQ-EAEEEAQPESDGVEAQPKSEGEEAQEVEGET-QK 2043
Query: 462 EEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQG 521
E +++P+ + V P+ + + Q + ++ P S+ D A + P + +G
Sbjct: 2044 TEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQP---ESEG 2100
Query: 522 HLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSS 581
PE + E+ K + PE++ + + S + ++ + S
Sbjct: 2101 VEAPEAEG---EAQKAEGIEA-------PETEGEAQPESEG-----IEAPEAEGEAQPES 2145
Query: 582 SSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHN 641
+ + S G + + + G + ++ SE G
Sbjct: 2146 EGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEA 2205
Query: 642 RDR----KHRRSVDRKRRDTSGLE------RSHKSSKGGSSRDTKGSKDKNSRSDRKRSI 691
+ + + + + + G+E + S+G + + KGS + +
Sbjct: 2206 QPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEA 2265
Query: 692 SESS 695
SESS
Sbjct: 2266 SESS 2269
Score = 53.1 bits (126), Expect = 9e-07
Identities = 79/433 (18%), Positives = 153/433 (35%), Gaps = 61/433 (14%)
Query: 306 EQEEGKVAQREEELEETGNQHNDVEIEEAGEE---EEKEIAIVHSDAEKEQEEEEQKQEM 362
E E+G+ +QR N+ D ++ EA + +E+E +S+ E E +QE
Sbjct: 1742 EGEDGEGSQRL-------NRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEG 1794
Query: 363 E-VKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEA 421
E + ET + S + + Q E DQ+ +++ E +E E E
Sbjct: 1795 EGISERGETGGQGSGHEDNLQGEAAAG------------GDQDPGQSDGAEGIEAPEAEG 1842
Query: 422 SKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQ 481
E +PE E P+ E +E E E E E E E QPE P+++
Sbjct: 1843 --EAQPESEGVEAPEAE----GDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAE 1896
Query: 482 PQLQLQSQSQPVLQSQPPSQPEDLSLAVL---------------QPTPQVTQE-QGHLLP 525
++Q +S+ +++ +QPE S+ L Q + QE +G P
Sbjct: 1897 WEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQP 1956
Query: 526 ERKDF-----------PVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSR 574
E + E V+ EV VE T E +++ ++ A + ++
Sbjct: 1957 ESEVIESQEAEEEAQPESEDVEALEVEVE---TQEAEGEAQPESEDVEAPEAEGEMQEAE 2013
Query: 575 SRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSR 634
+ S + S + + ++ + + G + ++ +
Sbjct: 2014 EEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQE 2073
Query: 635 SRGRGH--NRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSIS 692
+ G H + D + + + ++ G+E + + + + + I
Sbjct: 2074 AEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIE 2133
Query: 693 ESSRSGKRSSRSE 705
G+ SE
Sbjct: 2134 APEAEGEAQPESE 2146
Score = 50.4 bits (119), Expect = 6e-06
Identities = 67/233 (28%), Positives = 103/233 (44%), Gaps = 29/233 (12%)
Query: 293 KEHQVVRNEEQKAE---QEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDA 349
+E + N EQ AE QEE ++ + +E E G Q V++EE EE + V +
Sbjct: 1281 EEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEE 1340
Query: 350 EKEQEEEEQKQEMEVKMEEETEV-RESEKQQDSQPEEVMDVLE---MVENVKHVIADQEV 405
KE E E Q QE E ++EE E E +++ Q EEV + E E ++ + ++ +
Sbjct: 1341 TKETEGEGQ-QEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGL 1399
Query: 406 METNRVESVEPSE-----NEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEE 460
E V E SE + S+E +P E E G+ + SA E E
Sbjct: 1400 PEEGSVHGQELSEASSPDGKGSQEDDPVQEEE-----------AGRASASA---EPCPAE 1445
Query: 461 KEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPT 513
E+ +EP P +++ P S + Q SQ +P L+ P + QPT
Sbjct: 1446 GTEEPTEP-PSHLSETDP-SASERQSGSQLEPGLEKPPGATMMGQEHTQAQPT 1496
Score = 38.9 bits (89), Expect = 0.017
Identities = 45/219 (20%), Positives = 86/219 (39%), Gaps = 28/219 (12%)
Query: 277 QINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGE 336
Q+ + + + ++E+ Q+ + ++ QEEG + +E E G Q + ++EE
Sbjct: 1302 QLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEE--- 1358
Query: 337 EEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEE--ETEVRESEKQQDSQPEEVMDVLEMVE 394
I + E QEE Q +E++ E + E E +++ PEE
Sbjct: 1359 -------IEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEE--------- 1402
Query: 395 NVKHVIADQEVMETNRVESVEPSENEASKELEP-EMEFEIEPDKECKSLSPGKENVSALD 453
+ QE+ E + + E++ +E E EP C + +
Sbjct: 1403 ---GSVHGQELSEASSPDGKGSQEDDPVQEEEAGRASASAEP---CPAEGTEEPTEPPSH 1456
Query: 454 MEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQP 492
+ + E++S Q EP + P + Q +Q+QP
Sbjct: 1457 LSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQP 1495
Score = 34.3 bits (77), Expect = 0.41
Identities = 73/309 (23%), Positives = 111/309 (35%), Gaps = 76/309 (24%)
Query: 327 NDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEV 386
N+ E E EE+ + + EQ E QE EV++EE E E E Q+ +
Sbjct: 1272 NEDEAERDSEEQ-------RASSNLEQLAENTVQE-EVQLEETKEGTEGEGLQEEAVQ-- 1321
Query: 387 MDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGK 446
+E K QE E ++E + +E E +E E ++E EIE G
Sbjct: 1322 ------LEETKTEEGLQE--EGVQLEETKETEGEGQQEEEAQLE-EIE--------ETGG 1364
Query: 447 ENVSALDMEKESEEKEEKESEPQPEPVAQ-------PQPQSQPQLQLQSQSQPVLQSQPP 499
E + ++ E E KE E Q E + + P+ S +L S P
Sbjct: 1365 EGLQEEGVQLE-EVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSP---DGKG 1420
Query: 500 SQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTR 559
SQ +D P +E G + P E TE P EP P S+T
Sbjct: 1421 SQEDD---------PVQEEEAGRASASAEPCPAEG---TEEPTEP-----PSHLSET--- 1460
Query: 560 SRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSR 619
S+S S + G G++ + + T G++ R
Sbjct: 1461 ------------------DPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQPTQGAAER 1502
Query: 620 DSSSSTSSS 628
SS + S++
Sbjct: 1503 SSSVACSAA 1511
Score = 31.2 bits (69), Expect = 3.5
Identities = 28/116 (24%), Positives = 48/116 (41%), Gaps = 31/116 (26%)
Query: 564 GRARNKTSKSRSRSSSSSSSSSSSTSS-----------SSGSSSSSGSSSSRS----SSS 608
G+AR +TS+ + +S + S SS G+ ++G++ +R S
Sbjct: 557 GKARAETSQQEASEGGDPASPALSLSSLRSDDLQAETQGQGTEQATGAAVTREPLVLGLS 616
Query: 609 SSSSTSGSSSRDSSSSTSSSSESRSRSRG----------------RGHNRDRKHRR 648
S + G+SS S+ ++S + R RSR RGH R +R+
Sbjct: 617 CSWDSEGASSTPSTCTSSQQGQRRHRSRASAMSSPSSPGLGRVAPRGHPRHSHYRK 672
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 89.4 bits (220), Expect = 1e-17
Identities = 103/440 (23%), Positives = 198/440 (45%), Gaps = 37/440 (8%)
Query: 109 KPALQSSVVATSKE-RTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQ 167
K AL+ ++V K R D+ +++ +R L+ + + T T RQ
Sbjct: 1936 KLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQ 1995
Query: 168 KRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNA 227
++ ++EQ+L ERK E+ L E+R E + + K+E + Q + +
Sbjct: 1996 RKMTQVEQELF-----ERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQR 2050
Query: 228 KIIKYIRT--KTKPHLFYIPGRM---CPATQKLIEESQRKMNALFEGRRIEFAEQINKME 282
K+ K R K + L P ++ A QKL + +RK+ I+ + +
Sbjct: 2051 KLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRD-ERKLTQ----EEIKMTKMKRALF 2105
Query: 283 ARPRRQSMKEKEHQVVRNE--EQKAE--QEEGKVAQREEELEETGNQHNDVEIEEAGEEE 338
+ RR S+++ + + + E+++E ++E K+A+++ +L + EE EE
Sbjct: 2106 VKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKL--ANKMRRMINKEEKMTEE 2163
Query: 339 EKEIAIVHSDAEKEQEEEEQKQEMEVK--MEEETEVRESEKQQDSQPEEVMDVLEMVENV 396
E ++A HS+ + EEE +E EV ++ R+ K+ D E+ ++ VE+
Sbjct: 2164 ESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESE 2223
Query: 397 KHVIADQEVM--ETNRVESVEPSENEASKELEPEMEFEI-EPDKECKSLSPGKENVSALD 453
+H + E + E + ES+ E E +E E E E+ E ++E K G+E
Sbjct: 2224 EHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEK----Q 2279
Query: 454 MEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPT 513
+EKE EEK++K+ E + E V + + + + ++ S+ + S + E SL
Sbjct: 2280 VEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSL------ 2333
Query: 514 PQVTQEQGHLLPERKDFPVE 533
+ + +L + K F ++
Sbjct: 2334 EEEVDREKEILKKEKQFKLQ 2353
Score = 68.6 bits (166), Expect = 2e-11
Identities = 81/405 (20%), Positives = 177/405 (43%), Gaps = 57/405 (14%)
Query: 88 GERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTR--RDLIQDQNMDEKGKQ----R 141
G+R+ + SR+ + K+PA + ++ ++ TR R L Q++ K K+ +
Sbjct: 2048 GQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVK 2107
Query: 142 NRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRA 201
RR+ ++++ K + + ++R E+ + + A ++RK RR + +E +
Sbjct: 2108 ERRL------SIEQSKLDIK-EWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKM 2160
Query: 202 KQTELRLLEQKVE-LAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQ 260
+ E +L + E + +EE ++I +++ + + +
Sbjct: 2161 TEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWR---------------------K 2199
Query: 261 RKMNALFEGRRIEFAEQINKMEARPR-RQSMKEKEHQVVRNEEQKAEQEEGKVAQREEEL 319
RK + + +F+ Q++++E+ + M+ ++ + E +E+EE + + E E
Sbjct: 2200 RKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREE 2259
Query: 320 EETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEV---RESE 376
EE + + + EE GEE++ E +K+++++E+ QE E EE+ E+ E+E
Sbjct: 2260 EEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETE 2319
Query: 377 KQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPD 436
D + EE LE + V ++E+++ + ++ ++ + E +
Sbjct: 2320 SLSDEEEEEESCSLE-----EEVDREKEILKKEKQFKLQEQRRKSLRGRERVLSI----- 2369
Query: 437 KECKSLSPGKENVSALDMEKESEEK------EEKESEPQPEPVAQ 475
+ + GK L + K +K E KE P P P Q
Sbjct: 2370 --LRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKTPVPVPEKQ 2412
Score = 66.6 bits (161), Expect = 8e-11
Identities = 119/620 (19%), Positives = 248/620 (40%), Gaps = 81/620 (13%)
Query: 157 KQESTVATERQKRRQE---IEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKV 213
++E +A +R+K +E + Q+ E+ +E+ K +++ + EE R + +L+E+K+
Sbjct: 1751 EEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKM 1810
Query: 214 ELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEE----SQRKMNALFEG 269
+LAQ +E W ++ TK K + Y + + L +E +QRK N L+
Sbjct: 1811 KLAQKRERWINSMEEL-----TKNK-MILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNK 1864
Query: 270 RRIEFAEQ-----------INKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEE 318
R+ +++ NK+ A+ + +EKE V++ +E+ AE E+ K+ Q E+
Sbjct: 1865 ERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKE-TVIKKKEKLAETEK-KLVQVEDS 1922
Query: 319 L----EETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVR- 373
L E+ + + +E+A + +K + E + +EE+ +E+K E ++R
Sbjct: 1923 LAKKQEKLAQEKMKLALEKAMVQGKKRLR-----GELDIAKEEKALNLEMKRLAEEKMRL 1977
Query: 374 --------ESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKEL 425
+ E + S+ ++ V + + K + ++ ++ +R+ ++E SE A +L
Sbjct: 1978 VEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESE-IAKGKL 2036
Query: 426 E---------------PEMEFEIEPDKECKSLSPGKEN--VSALDM----EKESEEKEEK 464
E + ++ +E S P K N + AL E++ ++E K
Sbjct: 2037 EFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIK 2096
Query: 465 ESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLL 524
++ + + + S Q +L + + + ++ LA Q ++ + ++
Sbjct: 2097 MTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQ--RKLANKMRRMI 2154
Query: 525 PERKDFPVESVKLTEVPVEPVLTVHPESKSK-------TKTRSRSRGRARNKTSKSRSRS 577
+ + E KL E +L E + K R R R A+ + K + +
Sbjct: 2155 NKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAK-RGDKPKEKF 2213
Query: 578 SSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRG 637
SS S S S + S SS + E +
Sbjct: 2214 SSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEE 2273
Query: 638 RGHNRD-RKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSR 696
G + K +K+++ E K + ++ S SD + E
Sbjct: 2274 EGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEE----EEEE 2329
Query: 697 SGKRSSRSERDRKSDRKDKR 716
S +R+++ +K+K+
Sbjct: 2330 SCSLEEEVDREKEILKKEKQ 2349
Score = 65.1 bits (157), Expect = 2e-10
Identities = 103/519 (19%), Positives = 220/519 (42%), Gaps = 50/519 (9%)
Query: 80 EGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRD---LIQDQNMDE 136
E + + G + E QE + K ++ + + SKE+ +D + ++ +
Sbjct: 1493 EEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSR 1552
Query: 137 KGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELF 196
+G+++ +++ Q+ QE ++R E+K +A+EERK + E +
Sbjct: 1553 EGEEKEQQVT-----EEQRHIQEEHKWARIHRKRARAEKK---RAQEERKLAQEEEKLAQ 1604
Query: 197 EERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTK--PHLFYIPGRMCPATQK 254
EER+ Q E +L + V++ Q E + K + T + L ++ +K
Sbjct: 1605 EERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKK 1664
Query: 255 LIEE----SQRKMNALFEGRRIEFAEQI--NKMEARPRRQSMKEKEHQVVRNEEQKAEQE 308
L ++ ++ + +G ++ + I K+E P+R+ + + + + E ++ E +
Sbjct: 1665 LAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWD 1724
Query: 309 EGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEE 368
+++ +EEEL NQ +EE + E+E A+ + +EE + QE E+ ++E
Sbjct: 1725 MEELSWKEEEL----NQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQE 1780
Query: 369 ETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSEN--EASKELE 426
+ ++ + +++ + E + E + K +A + N +E + ++ K L
Sbjct: 1781 KEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLA 1840
Query: 427 PEMEFEIEPDKECKSLSPGKENV------------------SALDM-EKESEEKEEKESE 467
E + + +KE L+ KEN+ + L M K + EEK ++
Sbjct: 1841 QEKK-NLAQEKE--KLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQ 1897
Query: 468 PQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQE-QGHL--L 524
+ + + + ++ + +L + + Q E + LA+ + Q + +G L
Sbjct: 1898 EKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIA 1957
Query: 525 PERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSR 563
E K +E +L E + V SK +T SR R
Sbjct: 1958 KEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQR 1996
Score = 56.2 bits (134), Expect = 1e-07
Identities = 92/501 (18%), Positives = 206/501 (41%), Gaps = 56/501 (11%)
Query: 93 RRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMD------------EKGKQ 140
++ES+ + D DV P + + + R D+IQ + E+ ++
Sbjct: 1295 KKESKVLLEDLDWDVVPP--EKKPIFIQEGAIREDMIQGVTQEVIRHKEVMPREEEQAQK 1352
Query: 141 RNRRIFGL-------LMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERR 193
+ R + GL G F + V ++ ++E ++ + ++ RK V+ ER+
Sbjct: 1353 KARDMLGLEETQVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPKQGRKAVQKERK 1412
Query: 194 ELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRT-------KTKPHLFYIPG 246
+R + E + E+ E+A L+E+ + K++ RT K + G
Sbjct: 1413 VGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHG 1472
Query: 247 RMCPATQKLIEESQRKMNALFE-----GRRIEFAEQINKMEARPRRQSMKEK-EHQVVRN 300
+ + EE ++++ E G ++ E++ + + + + + K+ E+ +
Sbjct: 1473 ETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSK 1532
Query: 301 EEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVH---SDAEKEQEEEE 357
+++ ++E +V EE E + V E+ +EE + A +H + AEK++ +EE
Sbjct: 1533 SKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEE 1592
Query: 358 QK---QEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESV 414
+K +E ++ EE +E K + + D EM + +E + +
Sbjct: 1593 RKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLS 1652
Query: 415 EPSENEASKELEPEMEFEIEPDKECKSLSPG----------KENVSALDMEKESEEKEEK 464
+ +E A K + ++E +E K G + V L +++ + +EK
Sbjct: 1653 QEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEK 1712
Query: 465 ESEPQPEPVAQPQPQ-SQPQLQLQSQSQPVLQSQPPSQPEDLSLA-----VLQPTPQVTQ 518
E + E + + S + +L + +++ + E+ +LA + + ++ Q
Sbjct: 1713 ELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQ 1772
Query: 519 EQGHLLPERKDFPVESVKLTE 539
E+ L+ E++ K+ E
Sbjct: 1773 EEELLIQEKEKLAQHKEKMPE 1793
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 89.0 bits (219), Expect = 1e-17
Identities = 76/201 (37%), Positives = 93/201 (46%), Gaps = 40/201 (19%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
S S++++ SRSR R+R+ + KSRSRS SS SS S S S S S S S SRS S S S
Sbjct: 184 SYSRSRSHSRSRSRSRH-SRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRS 242
Query: 612 --STSGSSSRDSSSSTSSS----------------------------------SESRSRS 635
S S S++ S S S S S+S+SRS
Sbjct: 243 KKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRS 302
Query: 636 RGRGHNRDRKHRRSVDRKRRDTSGL--ERSHKSSKGGS-SRDTKGSKDKNSRSDRKRSIS 692
R + + + R SV R R L RS SKGGS SR SK K+ R RKRS
Sbjct: 303 RSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSRE 362
Query: 693 ESSRSGKRSSRSERDRKSDRK 713
ES + S+SER RK K
Sbjct: 363 ESRSRSRSRSKSERSRKRGSK 383
Score = 77.8 bits (190), Expect = 3e-14
Identities = 77/272 (28%), Positives = 111/272 (40%), Gaps = 20/272 (7%)
Query: 461 KEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQ 520
K S ++ + +S+ + +S+S+ QS+ S+ E + + +
Sbjct: 203 KSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSA 262
Query: 521 GHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGR---ARNKTSKSRSRS 577
G + KD E ++ + +P KSK+K+RSRS+ R + S SR RS
Sbjct: 263 GKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRS 322
Query: 578 SSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSG-SSSRDSSSSTSSSSESRSRSR 636
S S S S S G S S SRS S S G SR+ S S S S RSR
Sbjct: 323 QEKSLRQSRSRSRSKGGS----RSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSR 378
Query: 637 GRGHNRDRKHRRSVDRKRRDTS-----------GLERSHKSSKGGSSRDTKGSKDKNSRS 685
RG RD K S +K+ DT ER H S+ S R+ +G + +
Sbjct: 379 KRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSE-SSQREGRGESENAGTN 437
Query: 686 DRKRSISESSRSGKRSSRSERDRKSDRKDKRR 717
RS S S+ K + SE +S K R
Sbjct: 438 QETRSRSRSNSKSKPNLPSESRSRSKSASKTR 469
Score = 70.5 bits (171), Expect = 5e-12
Identities = 71/303 (23%), Positives = 129/303 (42%), Gaps = 22/303 (7%)
Query: 417 SENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQP 476
S + +SK + +S S + + +++S +++S + +
Sbjct: 206 SRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKS 265
Query: 477 QPQSQPQLQLQSQSQPVL---QSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVE 533
+ +S+ Q + + Q+ + +S+ PS+ + S + + + +E+ R +
Sbjct: 266 RSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEK 325
Query: 534 SVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKT-SKSRSRSSSSSSSS---SSSTS 589
S++ + S+S++K++ + +GR R++ S+SRSRS S S S S
Sbjct: 326 SLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRD 385
Query: 590 SSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRS 649
S +GSS + S S S S S S R+ + S SS E R S G N++ + R
Sbjct: 386 SKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSR-- 443
Query: 650 VDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRK 709
RS+ SK +++ S+ K++ R RS S SRS RS R R
Sbjct: 444 -----------SRSNSKSKPNLPSESR-SRSKSASKTRSRSKSR-SRSASRSPSRSRSRS 490
Query: 710 SDR 712
R
Sbjct: 491 HSR 493
Score = 59.3 bits (142), Expect = 1e-08
Identities = 56/169 (33%), Positives = 70/169 (41%), Gaps = 15/169 (8%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSS-SGSSSSRSSSSS 609
E T+ R +K R RS S S S S S S S S S S S SS+SS S
Sbjct: 158 EKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSK 217
Query: 610 SSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKG 669
S S S S SR SRS+SR R +R R ++ R RSH + K
Sbjct: 218 SRSRSRSGSR-----------SRSKSRSRSQSRSRS-KKEKSRSPSKEKSRSRSHSAGKS 265
Query: 670 GS-SRDTKGSK-DKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKR 716
S S+D K N + +S S S K SRS + ++KR
Sbjct: 266 RSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKR 314
Score = 58.5 bits (140), Expect = 2e-08
Identities = 66/255 (25%), Positives = 98/255 (38%), Gaps = 27/255 (10%)
Query: 437 KECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQP-----QPQSQPQLQLQSQSQ 491
K+ KS SP KE + S K +S+ Q E Q +P+S+ + +S+S+
Sbjct: 243 KKEKSRSPSKEKSRS---RSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSK 299
Query: 492 PVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPE 551
+SQ E+ +V + Q + R S + +
Sbjct: 300 SRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKR 359
Query: 552 SKSKTKTRSRSRG---RARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSS 608
S+ ++++RSRSR R+R + SK S++ SS T S S S S R +
Sbjct: 360 SREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAK 419
Query: 609 SSSS----------------TSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDR 652
S SS T S +S S + SESRSRS+ R R RS
Sbjct: 420 SESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSA 479
Query: 653 KRRDTSGLERSHKSS 667
R + RSH S
Sbjct: 480 SRSPSRSRSRSHSRS 494
Score = 45.1 bits (105), Expect = 2e-04
Identities = 64/308 (20%), Positives = 121/308 (39%), Gaps = 48/308 (15%)
Query: 279 NKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDV--EIEEAGE 336
++ ++ R +S KEK + + + GK + ++ E Q+ND + +
Sbjct: 232 SRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP 291
Query: 337 EEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENV 396
K + S +++ + EEE++ + +E +R+S + S+ ++
Sbjct: 292 SRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSK 351
Query: 397 KHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEK 456
+ E +R S S++E S ++ S D +
Sbjct: 352 DKRKGRKRSREESRSRSRSRSKSERS-----------------------RKRGSKRDSKA 388
Query: 457 ESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQV 516
S +K++KE + + + + S+ + +S+S SQ + E + Q T
Sbjct: 389 GSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSES-----SQREGRGESENAGTNQETRSR 443
Query: 517 TQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKT-SKSRS 575
++ P + P ES SKS +KTRSRS+ R+R+ + S SRS
Sbjct: 444 SRSNSKSKP---NLPSES--------------RSRSKSASKTRSRSKSRSRSASRSPSRS 486
Query: 576 RSSSSSSS 583
RS S S S
Sbjct: 487 RSRSHSRS 494
Score = 35.8 bits (81), Expect = 0.14
Identities = 22/79 (27%), Positives = 31/79 (39%)
Query: 639 GHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSG 698
G R R + RS R + S+ GSS+ + SRS + SRS
Sbjct: 178 GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQ 237
Query: 699 KRSSRSERDRKSDRKDKRR 717
RS + +S K+K R
Sbjct: 238 SRSRSKKEKSRSPSKEKSR 256
Score = 34.7 bits (78), Expect = 0.32
Identities = 41/181 (22%), Positives = 74/181 (40%), Gaps = 15/181 (8%)
Query: 4 AVRTLQEQLEKAKESLKNVDENIRKLTGRDPND--------VRPIQARLLALSGPGGGRG 55
A ++ + ++A+E ++N D N+ K R P+ R + R+ RG
Sbjct: 262 AGKSRSKSKDQAEEKIQNND-NVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRG 320
Query: 56 RG---SLLLRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQES---DPEDDDVKK 109
R SL R S S GG ++ R + + G +R+R ESR S + K+
Sbjct: 321 RSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKR 380
Query: 110 PALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKR 169
+ + S +SK++ + D + Q+ R + ++ + ES A Q+
Sbjct: 381 GSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQET 440
Query: 170 R 170
R
Sbjct: 441 R 441
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 89.0 bits (219), Expect = 1e-17
Identities = 98/449 (21%), Positives = 207/449 (46%), Gaps = 62/449 (13%)
Query: 82 AVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRR--------------D 127
AV +L GE R +S ++++ S VAT K++ R +
Sbjct: 140 AVKQLEGEARDLISRLHDSWKFAGELEQAL---SAVATQKKKADRYIEELTKERDALSLE 196
Query: 128 LIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEI------EQKLEVQA 181
L ++ DE+ K++N ++ L ++ K E + + KR+ E +Q+L+ +A
Sbjct: 197 LYRNTITDEELKEKNAKLQEKLQ-LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEA 255
Query: 182 EEERKQVEN---------ERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKY 232
+ K++++ E EL+ R +Q E ++ Q+ ++ + +E+ E KI +
Sbjct: 256 DHLGKELQSVSAKLQAQVEENELWN-RLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQ 314
Query: 233 I-RTKTKPHLFYIPGRMCPATQKLIEESQRKMNAL----FEGRRIEFAEQINKMEARPRR 287
+ + + + + ++++ E + K+ L E +I E+ + E + R
Sbjct: 315 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIRE 374
Query: 288 QSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHS 347
Q ++++ + +E+K ++E K+ ++EE ++E + E+ GE+EEK
Sbjct: 375 QEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQE--------QEEKMGEQEEK------- 419
Query: 348 DAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQE--- 404
EQEEE Q+QE +++ +EE ++RE EK+ Q E++ + EM++ + + +QE
Sbjct: 420 --MWEQEEEMQEQEEKMRRQEE-KIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKM 476
Query: 405 -VMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSAL-DMEKESEEKE 462
E E E + K E E + + +K + +E + + E++ E+E
Sbjct: 477 CEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE 536
Query: 463 EKESEPQPEPVAQPQPQSQPQLQLQSQSQ 491
EK E + + Q + + +++L+ Q +
Sbjct: 537 EKMQEQEEKMRRQEEKMREQEVRLRQQEE 565
Score = 80.9 bits (198), Expect = 4e-15
Identities = 75/290 (25%), Positives = 145/290 (50%), Gaps = 26/290 (8%)
Query: 156 FKQESTVATERQKRRQEIEQKLEVQAEEERKQVE------NERRELFEERRAKQTELRLL 209
++QE + ER+++ QE E+K+ Q E+ R+Q E + R E K+ ++R L
Sbjct: 291 WRQEEKIQ-EREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 349
Query: 210 EQKV---ELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQ--RKMN 264
E+K+ E + QEE + KI + + + + +M +K+ E+ + R+
Sbjct: 350 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE------AKMWRQEEKIREQEEKIREQE 403
Query: 265 ALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGN 324
+ + + + EQ KM + + M+E+E ++ R EE+ EQE+ K+ ++EE++ E
Sbjct: 404 EMMQEQEEKMGEQEEKMWEQ--EEEMQEQEEKMRRQEEKIREQEK-KIREQEEKIREQEE 460
Query: 325 QHNDVEIEEAGEEEEK---EIAIVHSDAEKEQEEEEQKQEMEVKM-EEETEVRESEKQQD 380
+ E E+ GE+E K + A + EK + +EE+ +E E K+ E+E ++RE E+
Sbjct: 461 MMQEQE-EKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 519
Query: 381 SQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPEME 430
Q E++ + E + + + +QE + E + E ++ E E
Sbjct: 520 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 73.9 bits (180), Expect = 5e-13
Identities = 64/317 (20%), Positives = 153/317 (48%), Gaps = 39/317 (12%)
Query: 157 KQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRE---LFE-ERRAKQTELRLLEQK 212
+Q+ ++++ QE E+K++ Q E+ R+Q E RR+ ++E E + ++ E + E++
Sbjct: 284 QQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 343
Query: 213 VELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRI 272
++ +L+E+ +E +K+ E+ +++ E +I
Sbjct: 344 EKIRELEEKMHEQ---------------------------EKIREQEEKRQ----EEEKI 372
Query: 273 EFAEQINKMEARPRRQSMKEKEHQV-VRNEEQKAEQEEGKVAQREEELEETGNQHNDVEI 331
E+ + EA+ RQ K +E + +R +E+ +++E K+ ++EE++ E + + E
Sbjct: 373 REQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE 432
Query: 332 EEAGEEE---EKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMD 388
+ +EE E+E I + + ++EE +++ E E+E ++ E E + Q E++
Sbjct: 433 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRR 492
Query: 389 VLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKEN 448
E + + I +QE + E ++ E + ++ E E E + ++ + + +E
Sbjct: 493 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 552
Query: 449 VSALDMEKESEEKEEKE 465
+ ++ +E++ +E
Sbjct: 553 MREQEVRLRQQEEKMQE 569
Score = 43.5 bits (101), Expect = 7e-04
Identities = 30/137 (21%), Positives = 67/137 (48%), Gaps = 4/137 (2%)
Query: 89 ERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIFGL 148
E + R + ++ + E+ ++ + E+ + Q+ M E+ +++ RR
Sbjct: 438 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQ-EEKMRRQEEK 496
Query: 149 LMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRL 208
+ +K +++ E+++ QE E+K+ E+E K E E + +E + ++ E ++
Sbjct: 497 IREQEKKIREQEEKIREQEEMMQEQEEKMW---EQEEKMCEQEEKMQEQEEKMRRQEEKM 553
Query: 209 LEQKVELAQLQEEWNEH 225
EQ+V L Q +E+ EH
Sbjct: 554 REQEVRLRQQEEKMQEH 570
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 89.0 bits (219), Expect = 1e-17
Identities = 62/163 (38%), Positives = 84/163 (51%), Gaps = 2/163 (1%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
SKS++ + S S ++ + S S S +S SS SS++S+SS SS SS SS S SSS SS+
Sbjct: 627 SKSESDS-SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685
Query: 612 STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGS 671
S+ S S DSS+S+ SS S S + D + S D ++S S SS
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSD 745
Query: 672 SRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D + SD S S+SS S S S+ SD D
Sbjct: 746 SSDSSNSSDSSDSSDSSNS-SDSSDSSDSSDSSDSSNSSDSND 787
Score = 85.1 bits (209), Expect = 2e-16
Identities = 59/164 (35%), Positives = 76/164 (46%), Gaps = 4/164 (2%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+SKS + + S + +S S + S+SS SS SS +S SS SS SS SS S SS SS
Sbjct: 637 DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
+S+ S S DSS S SS S S S + S D+S S SS
Sbjct: 697 NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS 756
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D + SD S+SS S S ++ SD D
Sbjct: 757 DSSDSSNSSDSSDSSDS----SDSSDSSNSSDSNDSSNSSDSSD 796
Score = 84.3 bits (207), Expect = 3e-16
Identities = 58/163 (35%), Positives = 77/163 (47%), Gaps = 1/163 (0%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
+ S + S S + + S S SS SS+SS SS SS S +SS S +SS S+SS SS
Sbjct: 910 NSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 969
Query: 612 STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGS 671
++ S S DSS+S+ SS S S + S D+S S SS +
Sbjct: 970 DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029
Query: 672 SRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D + SD S S+SS S S S+ SD D
Sbjct: 1030 SSDSSDSSDSSDSSDSSDS-SDSSDSSNSSDSSDSSDSSDSSD 1071
Score = 84.3 bits (207), Expect = 3e-16
Identities = 61/165 (36%), Positives = 77/165 (46%), Gaps = 2/165 (1%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
+ S + S S + + S S SS SS S+SS +S SS SS SS SS S SS SS
Sbjct: 940 NSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSD 999
Query: 612 STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGS 671
S++ S S DSS S+ SS+ S S + N S D+S S SS
Sbjct: 1000 SSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1059
Query: 672 SRDTKGSKDKNSRSDRKRS--ISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D + SD S SESS S S+ S+ SD D
Sbjct: 1060 SSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSD 1104
Score = 84.0 bits (206), Expect = 5e-16
Identities = 59/161 (36%), Positives = 72/161 (44%), Gaps = 1/161 (0%)
Query: 554 SKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSST 613
S + S S + N S S SS SS SS SS SS S +SS S +SS S S+SS S+
Sbjct: 918 SNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS 977
Query: 614 SGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSR 673
S+S DSS S+ SS S S + S D+S S SS S
Sbjct: 978 DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037
Query: 674 DTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
D+ S D + SD S S SS S S S+ SD D
Sbjct: 1038 DSSDSSDSSDSSDSSDS-SNSSDSSDSSDSSDSSDSSDSSD 1077
Score = 83.6 bits (205), Expect = 6e-16
Identities = 63/169 (37%), Positives = 84/169 (49%), Gaps = 7/169 (4%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
S S + S +++ +SKS S SS S S S SS S+SS SS +S SS S +SS+SS
Sbjct: 608 SDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSD 667
Query: 612 STSGSSSRDSSSST--SSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHK---- 665
S+ S S DSSSS+ S+SS+S S + S D D+S S+
Sbjct: 668 SSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSD 727
Query: 666 SSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
SS S D+ S D + SD S S+SS S S+ S+ SD D
Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNS-SDSSDSSDSSNSSDSSDSSDSSD 775
Score = 83.2 bits (204), Expect = 8e-16
Identities = 60/158 (37%), Positives = 75/158 (47%), Gaps = 1/158 (0%)
Query: 554 SKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSST 613
S + S S + + S + S SS+SS SS+SS SS S SS SS SS+S SS SS S+
Sbjct: 933 SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992
Query: 614 SGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSR 673
S S DSS+S+ SS S S + S D+S S SS S
Sbjct: 993 DSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052
Query: 674 DTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSD 711
D+ S D + SD S S+SS S S SE SD
Sbjct: 1053 DSSNSSDSSDSSDSSDS-SDSSDSSDSSDSSESSDSSD 1089
Score = 82.8 bits (203), Expect = 1e-15
Identities = 63/165 (38%), Positives = 81/165 (49%), Gaps = 3/165 (1%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSS-SSRSSSSS 609
+S + + + S + +S S S S SS+SS SS +S SS SS SS SS SS S SS
Sbjct: 655 DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSD 714
Query: 610 SSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKG 669
SS +S S+S DS SS SS S S S + D + S D+S S SS
Sbjct: 715 SSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSN-SSDSSDSSDSSNSSDSSDSSDS 773
Query: 670 GSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D N S+ S S+SS S S+ S+ SD D
Sbjct: 774 SDSSDSSNSSDSNDSSNSSDS-SDSSNSSDSSNSSDSSDSSDSSD 817
Score = 82.8 bits (203), Expect = 1e-15
Identities = 59/164 (35%), Positives = 76/164 (46%), Gaps = 1/164 (0%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
S S + S S R+ + S S SS SS+SS SS SS S SS+S SS S+SS S
Sbjct: 845 SDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSD 904
Query: 612 STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGS 671
S+ S+S DSS S++SS S S + N S D+S S SS +
Sbjct: 905 SSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSN 964
Query: 672 SRDTKGSKDKNSR-SDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S +S S S+SS S S S+ SD D
Sbjct: 965 SSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSD 1008
Score = 82.8 bits (203), Expect = 1e-15
Identities = 59/163 (36%), Positives = 74/163 (45%), Gaps = 1/163 (0%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
+ S S S + + S S SS SS+SS SS SS S S+SS SS S +SS SS
Sbjct: 928 NSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSD 987
Query: 612 STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGS 671
S+ S S DSS S++SS S S N S D+S S SS
Sbjct: 988 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047
Query: 672 SRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S + + SD S S+SS S S S+ SD D
Sbjct: 1048 SSDSSDSSNSSDSSDSSDS-SDSSDSSDSSDSSDSSESSDSSD 1089
Score = 82.8 bits (203), Expect = 1e-15
Identities = 59/163 (36%), Positives = 75/163 (46%), Gaps = 1/163 (0%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
S + + S + +S S S+SS SS SS +S SS SS SS SS S +SS SS
Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1062
Query: 612 STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGS 671
S+ S S DSS S+ SS S S N S D+S S SS +
Sbjct: 1063 SSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1122
Query: 672 SRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D + SD S S+SS S + S S+ SD D
Sbjct: 1123 SSDSSDSSDSSDSSDSSNS-SDSSDSSESSDSSDSSDSSDSSD 1164
Score = 82.4 bits (202), Expect = 1e-15
Identities = 59/161 (36%), Positives = 76/161 (47%), Gaps = 1/161 (0%)
Query: 554 SKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSST 613
S + + S + +S S S SS SS SS++S SS SS SS SS+S SS+SS S+
Sbjct: 969 SDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSS 1028
Query: 614 SGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSR 673
+ S S DSS S+ SS S S N S D+S S SS+ S
Sbjct: 1029 NSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSS 1088
Query: 674 DTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
D+ S D + SD S S+SS S S S+ SD D
Sbjct: 1089 DSSNSSDSSDSSDSSDS-SDSSDSSDSSDSSDSSNSSDSSD 1128
Score = 82.0 bits (201), Expect = 2e-15
Identities = 59/164 (35%), Positives = 75/164 (45%), Gaps = 1/164 (0%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S + + S + +S S + S SS SS SS +S SS SS SS SS S SS SS
Sbjct: 1032 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSS 1091
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
+S+ S S DSS S+ SS S S N S D+S S SS+
Sbjct: 1092 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESS 1151
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D + SD S S+SS S S S+ SD D
Sbjct: 1152 DSSDSSDSSDSSDSSDSSDS-SDSSDSSNSSDSSDSSDSSDSSD 1194
Score = 81.6 bits (200), Expect = 2e-15
Identities = 64/173 (36%), Positives = 85/173 (49%), Gaps = 10/173 (5%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSS-SSRSSSSSS 610
+ S + S S + + S + SS+SS SS SS SS S SS SS SS SS SS+SS
Sbjct: 863 NSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSD 922
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRR-------SVDRKRRDTSGLERS 663
SS S +SS +S+SS SS+S S S ++ D + S D D+S S
Sbjct: 923 SSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNS 982
Query: 664 HKSSKGGSSRDTKGSKDKNSRSDRKRS--ISESSRSGKRSSRSERDRKSDRKD 714
SS S D+ S D ++ SD S S+SS S S+ S+ SD D
Sbjct: 983 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 1035
Score = 81.6 bits (200), Expect = 2e-15
Identities = 58/166 (34%), Positives = 77/166 (46%), Gaps = 2/166 (1%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S + + S + +S S S+SS SS+SS +S+SS SS SS SS S SS SS
Sbjct: 990 DSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSS 1049
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S+ S+S DSS S+ SS S S + S D+S S SS
Sbjct: 1050 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSS 1109
Query: 671 SSRDTKGSKDKNSRSDRKRS--ISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D ++ SD S S+SS S S S+ SD D
Sbjct: 1110 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSD 1155
Score = 81.3 bits (199), Expect = 3e-15
Identities = 83/416 (19%), Positives = 144/416 (34%), Gaps = 23/416 (5%)
Query: 300 NEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQK 359
+E G + +E ++ GN + E+ + + +SD+
Sbjct: 479 SESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTN--NSDSNGNGNNGNDD 536
Query: 360 QEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSEN 419
+ + +++ +S+ S + D + + + +D + +++ +S + +
Sbjct: 537 NDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSS 596
Query: 420 EASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEK-ESEEKEEKESEPQPEPVAQPQP 478
++S + + + S K + S + + +S+ K + +
Sbjct: 597 DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDS 656
Query: 479 QSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLT 538
S S S S D S + E D S
Sbjct: 657 SDSSNSSNSSDSSDSSDSSDSSSSSDSS----NSSDSSDSSDSSNSSESSDSSDSS---- 708
Query: 539 EVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSS 598
+S S + S + + + +S S S SS+SS SS +S SS SS SS
Sbjct: 709 ------------DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS 756
Query: 599 GSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTS 658
SS S +SS SS S+ S S DSS+S+ S+ S S N S D+S
Sbjct: 757 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS 816
Query: 659 GLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
+ S+ S SS + S +S S S S RS S SD D
Sbjct: 817 DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD 872
Score = 81.3 bits (199), Expect = 3e-15
Identities = 88/422 (20%), Positives = 144/422 (34%), Gaps = 29/422 (6%)
Query: 300 NEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQK 359
++ K++ +GK + + ++ N + + ++ + + S + +
Sbjct: 535 DDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSD 594
Query: 360 QEMEVKMEEETEVRESEKQQDSQP--EEVMDVLEMVENVKHVIADQEVMETNRVESVEPS 417
+ ++ +S DS + D + + + + ++N +S + S
Sbjct: 595 SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNS 654
Query: 418 ENEASKELEPEMEFEIEPDKECKSLSPGKENVS-ALDMEKESEEKEEKESEPQPEPVAQP 476
++ S + D S S N S + D S E +S + +
Sbjct: 655 DSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSD 714
Query: 477 QPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVK 536
S S S S S D S D S
Sbjct: 715 SSDSSNSNSSDSDSSNSSDSSDSSNSSDSS----------------------DSSDSSNS 752
Query: 537 LTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSS 596
S S + S + + S S SS SS+SS S++SS S S
Sbjct: 753 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDS 812
Query: 597 SSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRD 656
S S S S+SS SS++S SS +SS +S SS+S S NR S D
Sbjct: 813 SDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD 872
Query: 657 TSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRS----ISESSRSGKRSSRSERDRKSDR 712
+S S SS S ++ S D ++ SD S S+SS S S SE SD
Sbjct: 873 SSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN 932
Query: 713 KD 714
+
Sbjct: 933 SN 934
Score = 81.3 bits (199), Expect = 3e-15
Identities = 59/164 (35%), Positives = 75/164 (45%), Gaps = 1/164 (0%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S + + + S + +S S S SS SS SS +S SS SS SS SS S SS SS
Sbjct: 1008 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1067
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S+ S S DSS S+ SS S S + + S D+S S SS
Sbjct: 1068 DSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1127
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D ++ SD S SESS S S S+ SD D
Sbjct: 1128 DSSDSSDSSDSSNSSDSSDS-SESSDSSDSSDSSDSSDSSDSSD 1170
Score = 80.9 bits (198), Expect = 4e-15
Identities = 58/163 (35%), Positives = 79/163 (48%), Gaps = 1/163 (0%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
S + + + S + +S S S SS+SS SS +S SS SS+SS SS+S SS+SS
Sbjct: 973 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSD 1032
Query: 612 STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGS 671
S+ S S DSS S+ SS S S + + S D+S S SS +
Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSN 1092
Query: 672 SRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D + SD S S+SS S S+ S+ SD D
Sbjct: 1093 SSDSSDSSDSSDSSDSSDS-SDSSDSSDSSNSSDSSDSSDSSD 1134
Score = 80.9 bits (198), Expect = 4e-15
Identities = 58/164 (35%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S + + S + +S S S+SS SS SS +S SS SS SS SS S +SS SS
Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 1034
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S+ S S DSS S+ SS S S + S D+S S SS
Sbjct: 1035 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSS 1094
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D + SD S S+SS S S S+ SD D
Sbjct: 1095 DSSDSSDSSDSSDSSDSSDS-SDSSDSSNSSDSSDSSDSSDSSD 1137
Score = 80.9 bits (198), Expect = 4e-15
Identities = 58/164 (35%), Positives = 77/164 (46%), Gaps = 1/164 (0%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S + + + S + +S S S SS SS SS +S SS SS+SS SS S SS SS
Sbjct: 1047 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSS 1106
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S+ S S DSS S++SS S S + S + D+S S SS
Sbjct: 1107 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSS 1166
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D ++ SD S S+SS S S S+ SD D
Sbjct: 1167 DSSDSSDSSDSSNSSDSSDS-SDSSDSSDSSDSSDSSDSSDSSD 1209
Score = 80.9 bits (198), Expect = 4e-15
Identities = 58/164 (35%), Positives = 76/164 (46%), Gaps = 1/164 (0%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S + + S + +S+S S SS+SS SS +S SS SS SS SS S SS SS
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1121
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
+S+ S S DSS S+ SS+ S S + S D+S S SS
Sbjct: 1122 NSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1181
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D + SD S S+SS S S S+ SD D
Sbjct: 1182 DSSDSSDSSDSSDSSDSSDS-SDSSDSSDSSDSSDSSDSSDSSD 1224
Score = 80.9 bits (198), Expect = 4e-15
Identities = 58/164 (35%), Positives = 76/164 (46%), Gaps = 1/164 (0%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S +++ S + +S S S SS SS SS +S SS SS+SS SS S SS SS
Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S++ S S DSS S+ SS S S + S D+S S SS
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1196
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D + SD S S+SS S S S+ + SD D
Sbjct: 1197 DSSDSSDSSDSSDSSDSSDS-SDSSDSSDSSDSSDSNESSDSSD 1239
Score = 80.5 bits (197), Expect = 5e-15
Identities = 57/161 (35%), Positives = 79/161 (49%), Gaps = 1/161 (0%)
Query: 554 SKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSST 613
S + S S + + S + S +S+SS SS+SS SS S SS+S SS+ S SS+SS +
Sbjct: 909 SNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDS 968
Query: 614 SGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSR 673
S S+S DSS S++SS S S + S D+S S SS S
Sbjct: 969 SDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSS 1028
Query: 674 DTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
++ S D + SD S S+SS S S+ S+ SD D
Sbjct: 1029 NSSDSSDSSDSSDSSDS-SDSSDSSDSSNSSDSSDSSDSSD 1068
Score = 80.1 bits (196), Expect = 7e-15
Identities = 58/164 (35%), Positives = 74/164 (45%), Gaps = 3/164 (1%)
Query: 552 SKSKTKTRSRSRGRARNKTSKS-RSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
S + + S G + +++S S SS SS SS SS SS S SS S SS+ S SS S
Sbjct: 838 SSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDS 897
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S++S S S DSS+S+ SS S S N S D+S S SS
Sbjct: 898 SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
+S D+ S D S S+SS S S S+ SD D
Sbjct: 958 NSSDSSNSSD--SSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSD 999
Score = 79.7 bits (195), Expect = 9e-15
Identities = 120/502 (23%), Positives = 195/502 (38%), Gaps = 85/502 (16%)
Query: 254 KLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVA 313
++IE S R EG E QIN +R KE E E+ + +G +
Sbjct: 198 EIIENSCRN-----EGNTSEITPQINS-----KRNGTKEAEVTPGTGEDAGLDNSDGSPS 247
Query: 314 QR-----------EEELEETGNQHNDV------EIEEAGEEEEKEIAIVHSDAEKEQEEE 356
++E EE GN + E ++ G+E++ + +I + KE +
Sbjct: 248 GNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDP 307
Query: 357 EQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEP 416
E K++ +++ + + E + +E + + H E+ RVE
Sbjct: 308 EGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNH-------RESKRVE---- 356
Query: 417 SENEASKELEPEMEFEIEPDK--ECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVA 474
N +KE E + + DK E K S G N++ ++ K +E KE+K
Sbjct: 357 --NRITKESETHAVGKSQ-DKGIEIKGPSSGNRNITK-EVGKGNEGKEDKGQHGM----- 407
Query: 475 QPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVES 534
+ +++Q + V P + E + T + G+ + DF +S
Sbjct: 408 -----ILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGY---DSYDFDDKS 459
Query: 535 VKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSS----SSTSS 590
++ + + ++ S++ S SRG A + +S+ + S S + S ++S
Sbjct: 460 MQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTS 519
Query: 591 SSGSSSSSG------------------SSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESR 632
+ +S S+G S SS S SS SS++S SS DSS S SS S S
Sbjct: 520 DTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSS--DSSDSDSSDSNSS 577
Query: 633 SRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSIS 692
S S + D S D D+S S SS S D+ S D S S + S S
Sbjct: 578 SDS----DSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDS 633
Query: 693 ESSRSGKRSSRSERDRKSDRKD 714
S S SS S SD D
Sbjct: 634 SDSDSKSDSSDSNSSDSSDNSD 655
Score = 79.7 bits (195), Expect = 9e-15
Identities = 57/164 (34%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S + + S + +S S + S SS SS SS +S SS SS SS SS+S SS SS
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S+ S S DSS S+ SS S S + S D+S S SS
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1124
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D + S+ S S+SS S S S+ SD D
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDS-SDSSESSDSSDSSDSSDSSDSSD 1167
Score = 79.7 bits (195), Expect = 9e-15
Identities = 58/163 (35%), Positives = 74/163 (45%), Gaps = 1/163 (0%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
S + + S + +S S S+SS SS SS +S SS SS SS SS S SS SS
Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSD 1089
Query: 612 STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGS 671
S++ S S DSS S+ SS S S + S D+S S SS
Sbjct: 1090 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSE 1149
Query: 672 SRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D + SD S S+SS S S+ S+ SD D
Sbjct: 1150 SSDSSDSSDSSDSSDSSDS-SDSSDSSDSSNSSDSSDSSDSSD 1191
Score = 79.7 bits (195), Expect = 9e-15
Identities = 58/164 (35%), Positives = 75/164 (45%), Gaps = 1/164 (0%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
ES + + + S + +S S S SS SS SS +S+SS SS SS SS S SS+SS
Sbjct: 1083 ESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 1142
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S+ S S DSS S+ SS S S + S D+S S SS
Sbjct: 1143 DSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1202
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D + SD S S+SS S + S+ SD D
Sbjct: 1203 DSSDSSDSSDSSDSSDSSDS-SDSSDSSDSNESSDSSDSSDSSD 1245
Score = 79.3 bits (194), Expect = 1e-14
Identities = 58/164 (35%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S + + S + +S S S SS SS+SS +S SS SS SS SS S SS SS
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1118
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S++ S S DSS S+ SS S S S D+S S SS
Sbjct: 1119 DSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1178
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
+S D+ S D + SD S S+SS S S S+ SD D
Sbjct: 1179 NSSDSSDSSDSSDSSDSSDS-SDSSDSSDSSDSSDSSDSSDSSD 1221
Score = 79.0 bits (193), Expect = 1e-14
Identities = 58/164 (35%), Positives = 73/164 (44%), Gaps = 1/164 (0%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S + + S + +S S S SS SS SS +S SS SS SS SS+S SS SS
Sbjct: 1041 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSS 1100
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S+ S S DSS S+ SS S S + S D+S S SS
Sbjct: 1101 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSS 1160
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D + SD S S+SS S S S+ SD D
Sbjct: 1161 DSSDSSDSSDSSDSSDSSNS-SDSSDSSDSSDSSDSSDSSDSSD 1203
Score = 79.0 bits (193), Expect = 1e-14
Identities = 58/164 (35%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S + + S + +S S S+SS SS SS +S SS SS+SS SS S SS SS
Sbjct: 1095 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S+ S S DSS S+ SS S S + + S D+S S SS
Sbjct: 1155 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1214
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D + SD S S+SS S S S SD D
Sbjct: 1215 DSSDSSDSSDSSDSSDSNES-SDSSDSSDSSDSSNSSDSSDSSD 1257
Score = 79.0 bits (193), Expect = 1e-14
Identities = 58/161 (36%), Positives = 73/161 (45%), Gaps = 1/161 (0%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S + + S + +S S S SS SS SS +S+SS SS SS SS S SS SS
Sbjct: 1101 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSS 1160
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S+ S S DSS S+ SS+ S S + S D+S S SS
Sbjct: 1161 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1220
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSD 711
S D+ S D N SD S S+SS S S S+ SD
Sbjct: 1221 DSSDSSDSSDSNESSDSSDS-SDSSDSSNSSDSSDSSDSSD 1260
Score = 78.6 bits (192), Expect = 2e-14
Identities = 55/165 (33%), Positives = 72/165 (43%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S + + S + +S S S SS SS SS++S SS SS SS SS S SS SS
Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSS 1163
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S+ S S DSS S++SS S S + S D+S S SS
Sbjct: 1164 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1223
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDK 715
S D+ S + + SD S S+ S S D SD D+
Sbjct: 1224 DSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDE 1268
Score = 78.2 bits (191), Expect = 2e-14
Identities = 57/166 (34%), Positives = 77/166 (46%), Gaps = 2/166 (1%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S + + + + S + +S S S SS SS SS++S SS SS SS SS S SS SS
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S+ S S DSS+S+ SS S S + S D+S S SS
Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1139
Query: 671 SSRDTKGSKDKNSRSDRKRS--ISESSRSGKRSSRSERDRKSDRKD 714
+S D+ S + + SD S S+SS S S S+ SD D
Sbjct: 1140 NSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1185
Score = 77.8 bits (190), Expect = 3e-14
Identities = 58/163 (35%), Positives = 77/163 (47%), Gaps = 1/163 (0%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
+ S + S S + +S S + S SS SS SS +S SS SS+SS SS S SS SS+
Sbjct: 958 NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSN 1017
Query: 612 STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGS 671
S+ S+S DSS+S+ SS S S + S D+S S SS
Sbjct: 1018 SSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1077
Query: 672 SRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ S D + S+ S S+SS S S S+ SD D
Sbjct: 1078 SSDSSESSDSSDSSNSSDS-SDSSDSSDSSDSSDSSDSSDSSD 1119
Score = 77.8 bits (190), Expect = 3e-14
Identities = 57/164 (34%), Positives = 74/164 (45%), Gaps = 1/164 (0%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S + + + S + +S S S SS+SS SS +S SS SS SS SS S SS SS
Sbjct: 1026 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESS 1085
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S+ S+S DSS S+ SS S S + S D+S S SS
Sbjct: 1086 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS 1145
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S ++ S D + SD S S+SS S S S SD D
Sbjct: 1146 DSSESSDSSDSSDSSDSSDS-SDSSDSSDSSDSSNSSDSSDSSD 1188
Score = 77.0 bits (188), Expect = 6e-14
Identities = 57/163 (34%), Positives = 74/163 (45%), Gaps = 1/163 (0%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
S + + S + +S S S SS SS SS++S SS SS SS SS S SS SS
Sbjct: 1057 SSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1116
Query: 612 STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGS 671
S+ S+S DSS S+ SS S S + + S D+S S SS
Sbjct: 1117 SSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSD 1176
Query: 672 SRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S ++ S D + SD S S+SS S S S+ SD D
Sbjct: 1177 SSNSSDSSDSSDSSDSSDS-SDSSDSSDSSDSSDSSDSSDSSD 1218
Score = 76.3 bits (186), Expect = 9e-14
Identities = 53/153 (34%), Positives = 68/153 (44%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
S + + S + +S S S SS SS SS +S SS SS SS SS S SS+SS
Sbjct: 1123 SSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1182
Query: 612 STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGS 671
S+ S S DSS S+ SS S S + S D+S S SS
Sbjct: 1183 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSD 1242
Query: 672 SRDTKGSKDKNSRSDRKRSISESSRSGKRSSRS 704
S D+ S D + SD S S+S+ S+S
Sbjct: 1243 SSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKS 1275
Score = 75.9 bits (185), Expect = 1e-13
Identities = 54/166 (32%), Positives = 71/166 (42%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S + + S + +S S S SS SS+SS +S SS SS SS SS S SS SS
Sbjct: 1107 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSS 1166
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S+ S S DSS+S+ SS S S + S D+S S SS
Sbjct: 1167 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1226
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKR 716
S D+ S D + SD S + S S S +D D +
Sbjct: 1227 DSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQ 1272
Score = 75.9 bits (185), Expect = 1e-13
Identities = 55/165 (33%), Positives = 74/165 (44%), Gaps = 6/165 (3%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S + + S + +S S + S SS SS SS +S SS SS SS SS S SS SS
Sbjct: 1116 DSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSS 1175
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S++ S S DSS S+ SS S S + S D+S S SS
Sbjct: 1176 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS------DSSDSSDSSDSSDSS 1229
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDK 715
S ++ S D + SD S S S S S+ + +SD + K
Sbjct: 1230 DSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274
Score = 75.9 bits (185), Expect = 1e-13
Identities = 55/158 (34%), Positives = 71/158 (44%), Gaps = 1/158 (0%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S + + + S +++S S S SS SS SS +S SS SS SS SS S SS SS
Sbjct: 1131 DSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1190
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S+ S S DSS S+ SS S S + S + D+S S SS
Sbjct: 1191 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSS 1250
Query: 671 SSRDTKGSKDKNSRS-DRKRSISESSRSGKRSSRSERD 707
S D+ S D S S D S S+S S S+ D
Sbjct: 1251 DSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSD 1288
Score = 72.8 bits (177), Expect = 1e-12
Identities = 54/164 (32%), Positives = 73/164 (44%), Gaps = 7/164 (4%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S + + + S + +S S S SS SS SS +S SS SS SS SS S SS SS
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1196
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S+ S S DSS S+ SS S S + + S D+S S SS
Sbjct: 1197 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSS 1256
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
S D+ + D N SD S+S ++ S+ D S+ D
Sbjct: 1257 DSSDS--TSDSNDESD-----SQSKSGNGNNNGSDSDSDSEGSD 1293
Score = 72.0 bits (175), Expect = 2e-12
Identities = 52/157 (33%), Positives = 69/157 (43%), Gaps = 2/157 (1%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
+S + + S + +S S S SS SS+SS +S SS SS SS SS S SS SS
Sbjct: 1146 DSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1205
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGG 670
S+ S S DSS S+ SS S S + S D+S + S S
Sbjct: 1206 DSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSS--DSSDSSDSTS 1263
Query: 671 SSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERD 707
S D S+ K+ + S S+S G S+ S D
Sbjct: 1264 DSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSD 1300
>gi|113415504 PREDICTED: similar to ribonucleic acid binding protein
S1 [Homo sapiens]
Length = 305
Score = 88.2 bits (217), Expect = 2e-17
Identities = 60/121 (49%), Positives = 72/121 (59%), Gaps = 9/121 (7%)
Query: 552 SKSKTKTRSRSRG---------RARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSS 602
S K+K RS+ +G R R+KT K S SS SSS+ S S+S+SS SS+S SS
Sbjct: 35 SDEKSKDRSKDKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSS 94
Query: 603 SRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLER 662
S SSSSS+SS SGSSS SSS+SSSS S S SR R NR R +S KR + R
Sbjct: 95 SGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRR 154
Query: 663 S 663
S
Sbjct: 155 S 155
Score = 78.6 bits (192), Expect = 2e-14
Identities = 55/114 (48%), Positives = 70/114 (61%), Gaps = 7/114 (6%)
Query: 547 TVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSS-SSSSTSSSSGSSSSSGSSSSRS 605
T K + + ++R R A + +S +RSRSSS+SSS SS+ST SSSGSSSSS SS S S
Sbjct: 49 TKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGS 108
Query: 606 SSSS-SSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTS 658
SS+S SSS+S SS S S + RSRS+ + RD K +RKRR S
Sbjct: 109 SSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEK-----ERKRRSPS 157
Score = 62.4 bits (150), Expect = 1e-09
Identities = 51/154 (33%), Positives = 71/154 (46%), Gaps = 13/154 (8%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
S +K K RS + + R+K K ++ SS T +SS S S+ SRSSS+SSS
Sbjct: 27 SPTKRKDRSDEKSKDRSK-DKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSS 85
Query: 612 -------STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTS-----G 659
S+SGSSS +SS + SSS SRS S RR D +RR S
Sbjct: 86 GSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPK 145
Query: 660 LERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISE 693
+ + + S + TK + +R+ K I E
Sbjct: 146 RDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIME 179
Score = 58.9 bits (141), Expect = 2e-08
Identities = 51/157 (32%), Positives = 71/157 (45%), Gaps = 32/157 (20%)
Query: 554 SKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSST 613
S TK + RS +++++ SK + + SS + S+SSGSSS+RS SSS+SS+
Sbjct: 27 SPTKRKDRSDEKSKDR-SKDKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSS 85
Query: 614 SGSSSRDSSS-STSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSS 672
S+S SSS S+SSS+ SRS S S RS SS S
Sbjct: 86 GSSTSTGSSSGSSSSSASSRSGS----------------------SSTSRSSSSSSSSGS 123
Query: 673 RDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRK 709
+ N R R +S K R E++RK
Sbjct: 124 PSPSRRRHDNRRRSRSKS--------KPPKRDEKERK 152
Score = 48.5 bits (114), Expect = 2e-05
Identities = 45/137 (32%), Positives = 57/137 (41%), Gaps = 8/137 (5%)
Query: 584 SSSSTSSSSGSSSSSGSSSSRSSSSSS-SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNR 642
S S G ++ SS+R+ S + S S+D S ++ ES + RGR R
Sbjct: 4 SGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTR 63
Query: 643 DRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISES-SRSGKRS 701
R S R RS +S GSS T S +S S RS S S SRS S
Sbjct: 64 KRHSASSGSSSTR-----SRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS 118
Query: 702 SRSERDRKSDRK-DKRR 717
S S S R+ D RR
Sbjct: 119 SSSGSPSPSRRRHDNRR 135
Score = 47.4 bits (111), Expect = 5e-05
Identities = 42/152 (27%), Positives = 64/152 (42%), Gaps = 14/152 (9%)
Query: 567 RNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTS 626
+ KS +R+ S + S S S G++ + SS + R S+SS S
Sbjct: 15 KENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGAT--KESSEKDRGRDKTRKRHSASSGS 72
Query: 627 SSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSD 686
SS+ SRS S + +SG S SS+ GSS ++ S +S S
Sbjct: 73 SSTRSRSSSTSSSGS---------STSTGSSSGSSSSSASSRSGSSSTSRSS--SSSSSS 121
Query: 687 RKRSISESSRSGKRSSRSE-RDRKSDRKDKRR 717
S S +R SRS+ + K D K+++R
Sbjct: 122 GSPSPSRRRHDNRRRSRSKSKPPKRDEKERKR 153
Score = 33.9 bits (76), Expect = 0.54
Identities = 28/80 (35%), Positives = 38/80 (47%), Gaps = 7/80 (8%)
Query: 503 EDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRS 562
E + VL P P+ T + P R+ P + L P + P +S + RSRS
Sbjct: 232 EITATVVLAPWPRPTPRR--FSPPRRMLPPPPMWLRSPPRMRRRSRSPRRRSPVRRRSRS 289
Query: 563 RGRARNKTSKSRSRSSSSSS 582
GR R+ RSRSSS+SS
Sbjct: 290 PGRRRH-----RSRSSSNSS 304
>gi|169166499 PREDICTED: similar to ribonucleic acid binding protein
S1 [Homo sapiens]
Length = 305
Score = 88.2 bits (217), Expect = 2e-17
Identities = 60/121 (49%), Positives = 72/121 (59%), Gaps = 9/121 (7%)
Query: 552 SKSKTKTRSRSRG---------RARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSS 602
S K+K RS+ +G R R+KT K S SS SSS+ S S+S+SS SS+S SS
Sbjct: 35 SDEKSKDRSKDKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSS 94
Query: 603 SRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLER 662
S SSSSS+SS SGSSS SSS+SSSS S S SR R NR R +S KR + R
Sbjct: 95 SGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRR 154
Query: 663 S 663
S
Sbjct: 155 S 155
Score = 78.6 bits (192), Expect = 2e-14
Identities = 55/114 (48%), Positives = 70/114 (61%), Gaps = 7/114 (6%)
Query: 547 TVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSS-SSSSTSSSSGSSSSSGSSSSRS 605
T K + + ++R R A + +S +RSRSSS+SSS SS+ST SSSGSSSSS SS S S
Sbjct: 49 TKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGS 108
Query: 606 SSSS-SSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTS 658
SS+S SSS+S SS S S + RSRS+ + RD K +RKRR S
Sbjct: 109 SSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEK-----ERKRRSPS 157
Score = 62.4 bits (150), Expect = 1e-09
Identities = 51/154 (33%), Positives = 71/154 (46%), Gaps = 13/154 (8%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
S +K K RS + + R+K K ++ SS T +SS S S+ SRSSS+SSS
Sbjct: 27 SPTKRKDRSDEKSKDRSK-DKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSS 85
Query: 612 -------STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTS-----G 659
S+SGSSS +SS + SSS SRS S RR D +RR S
Sbjct: 86 GSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPK 145
Query: 660 LERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISE 693
+ + + S + TK + +R+ K I E
Sbjct: 146 RDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIME 179
Score = 58.9 bits (141), Expect = 2e-08
Identities = 51/157 (32%), Positives = 71/157 (45%), Gaps = 32/157 (20%)
Query: 554 SKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSST 613
S TK + RS +++++ SK + + SS + S+SSGSSS+RS SSS+SS+
Sbjct: 27 SPTKRKDRSDEKSKDR-SKDKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSS 85
Query: 614 SGSSSRDSSS-STSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSS 672
S+S SSS S+SSS+ SRS S S RS SS S
Sbjct: 86 GSSTSTGSSSGSSSSSASSRSGS----------------------SSTSRSSSSSSSSGS 123
Query: 673 RDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRK 709
+ N R R +S K R E++RK
Sbjct: 124 PSPSRRRHDNRRRSRSKS--------KPPKRDEKERK 152
Score = 48.5 bits (114), Expect = 2e-05
Identities = 45/137 (32%), Positives = 57/137 (41%), Gaps = 8/137 (5%)
Query: 584 SSSSTSSSSGSSSSSGSSSSRSSSSSS-SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNR 642
S S G ++ SS+R+ S + S S+D S ++ ES + RGR R
Sbjct: 4 SGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTR 63
Query: 643 DRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISES-SRSGKRS 701
R S R RS +S GSS T S +S S RS S S SRS S
Sbjct: 64 KRHSASSGSSSTR-----SRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS 118
Query: 702 SRSERDRKSDRK-DKRR 717
S S S R+ D RR
Sbjct: 119 SSSGSPSPSRRRHDNRR 135
Score = 47.4 bits (111), Expect = 5e-05
Identities = 42/152 (27%), Positives = 64/152 (42%), Gaps = 14/152 (9%)
Query: 567 RNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTS 626
+ KS +R+ S + S S S G++ + SS + R S+SS S
Sbjct: 15 KENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGAT--KESSEKDRGRDKTRKRHSASSGS 72
Query: 627 SSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSD 686
SS+ SRS S + +SG S SS+ GSS ++ S +S S
Sbjct: 73 SSTRSRSSSTSSSGS---------STSTGSSSGSSSSSASSRSGSSSTSRSS--SSSSSS 121
Query: 687 RKRSISESSRSGKRSSRSE-RDRKSDRKDKRR 717
S S +R SRS+ + K D K+++R
Sbjct: 122 GSPSPSRRRHDNRRRSRSKSKPPKRDEKERKR 153
Score = 33.9 bits (76), Expect = 0.54
Identities = 28/80 (35%), Positives = 38/80 (47%), Gaps = 7/80 (8%)
Query: 503 EDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRS 562
E + VL P P+ T + P R+ P + L P + P +S + RSRS
Sbjct: 232 EITATVVLAPWPRPTPRR--FSPPRRMLPPPPMWLRSPPRMRRRSRSPRRRSPVRRRSRS 289
Query: 563 RGRARNKTSKSRSRSSSSSS 582
GR R+ RSRSSS+SS
Sbjct: 290 PGRRRH-----RSRSSSNSS 304
>gi|113415498 PREDICTED: similar to ribonucleic acid binding protein
S1 [Homo sapiens]
Length = 305
Score = 88.2 bits (217), Expect = 2e-17
Identities = 60/121 (49%), Positives = 72/121 (59%), Gaps = 9/121 (7%)
Query: 552 SKSKTKTRSRSRG---------RARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSS 602
S K+K RS+ +G R R+KT K S SS SSS+ S S+S+SS SS+S SS
Sbjct: 35 SDEKSKDRSKDKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSS 94
Query: 603 SRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLER 662
S SSSSS+SS SGSSS SSS+SSSS S S SR R NR R +S KR + R
Sbjct: 95 SGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRR 154
Query: 663 S 663
S
Sbjct: 155 S 155
Score = 78.6 bits (192), Expect = 2e-14
Identities = 55/114 (48%), Positives = 70/114 (61%), Gaps = 7/114 (6%)
Query: 547 TVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSS-SSSSTSSSSGSSSSSGSSSSRS 605
T K + + ++R R A + +S +RSRSSS+SSS SS+ST SSSGSSSSS SS S S
Sbjct: 49 TKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGS 108
Query: 606 SSSS-SSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTS 658
SS+S SSS+S SS S S + RSRS+ + RD K +RKRR S
Sbjct: 109 SSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEK-----ERKRRSPS 157
Score = 62.4 bits (150), Expect = 1e-09
Identities = 51/154 (33%), Positives = 71/154 (46%), Gaps = 13/154 (8%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
S +K K RS + + R+K K ++ SS T +SS S S+ SRSSS+SSS
Sbjct: 27 SPTKRKDRSDEKSKDRSK-DKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSS 85
Query: 612 -------STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTS-----G 659
S+SGSSS +SS + SSS SRS S RR D +RR S
Sbjct: 86 GSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPK 145
Query: 660 LERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISE 693
+ + + S + TK + +R+ K I E
Sbjct: 146 RDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIME 179
Score = 58.9 bits (141), Expect = 2e-08
Identities = 51/157 (32%), Positives = 71/157 (45%), Gaps = 32/157 (20%)
Query: 554 SKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSST 613
S TK + RS +++++ SK + + SS + S+SSGSSS+RS SSS+SS+
Sbjct: 27 SPTKRKDRSDEKSKDR-SKDKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSS 85
Query: 614 SGSSSRDSSS-STSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSS 672
S+S SSS S+SSS+ SRS S S RS SS S
Sbjct: 86 GSSTSTGSSSGSSSSSASSRSGS----------------------SSTSRSSSSSSSSGS 123
Query: 673 RDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRK 709
+ N R R +S K R E++RK
Sbjct: 124 PSPSRRRHDNRRRSRSKS--------KPPKRDEKERK 152
Score = 48.5 bits (114), Expect = 2e-05
Identities = 45/137 (32%), Positives = 57/137 (41%), Gaps = 8/137 (5%)
Query: 584 SSSSTSSSSGSSSSSGSSSSRSSSSSS-SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNR 642
S S G ++ SS+R+ S + S S+D S ++ ES + RGR R
Sbjct: 4 SGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTR 63
Query: 643 DRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISES-SRSGKRS 701
R S R RS +S GSS T S +S S RS S S SRS S
Sbjct: 64 KRHSASSGSSSTR-----SRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS 118
Query: 702 SRSERDRKSDRK-DKRR 717
S S S R+ D RR
Sbjct: 119 SSSGSPSPSRRRHDNRR 135
Score = 47.4 bits (111), Expect = 5e-05
Identities = 42/152 (27%), Positives = 64/152 (42%), Gaps = 14/152 (9%)
Query: 567 RNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTS 626
+ KS +R+ S + S S S G++ + SS + R S+SS S
Sbjct: 15 KENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGAT--KESSEKDRGRDKTRKRHSASSGS 72
Query: 627 SSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSD 686
SS+ SRS S + +SG S SS+ GSS ++ S +S S
Sbjct: 73 SSTRSRSSSTSSSGS---------STSTGSSSGSSSSSASSRSGSSSTSRSS--SSSSSS 121
Query: 687 RKRSISESSRSGKRSSRSE-RDRKSDRKDKRR 717
S S +R SRS+ + K D K+++R
Sbjct: 122 GSPSPSRRRHDNRRRSRSKSKPPKRDEKERKR 153
Score = 33.9 bits (76), Expect = 0.54
Identities = 28/80 (35%), Positives = 38/80 (47%), Gaps = 7/80 (8%)
Query: 503 EDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRS 562
E + VL P P+ T + P R+ P + L P + P +S + RSRS
Sbjct: 232 EITATVVLAPWPRPTPRR--FSPPRRMLPPPPMWLRSPPRMRRRSRSPRRRSPVRRRSRS 289
Query: 563 RGRARNKTSKSRSRSSSSSS 582
GR R+ RSRSSS+SS
Sbjct: 290 PGRRRH-----RSRSSSNSS 304
>gi|88973230 PREDICTED: similar to ribonucleic acid binding protein
S1 isoform 3 [Homo sapiens]
Length = 305
Score = 88.2 bits (217), Expect = 2e-17
Identities = 60/121 (49%), Positives = 72/121 (59%), Gaps = 9/121 (7%)
Query: 552 SKSKTKTRSRSRG---------RARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSS 602
S K+K RS+ +G R R+KT K S SS SSS+ S S+S+SS SS+S SS
Sbjct: 35 SDEKSKDRSKDKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSS 94
Query: 603 SRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLER 662
S SSSSS+SS SGSSS SSS+SSSS S S SR R NR R +S KR + R
Sbjct: 95 SGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRR 154
Query: 663 S 663
S
Sbjct: 155 S 155
Score = 78.6 bits (192), Expect = 2e-14
Identities = 55/114 (48%), Positives = 70/114 (61%), Gaps = 7/114 (6%)
Query: 547 TVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSS-SSSSTSSSSGSSSSSGSSSSRS 605
T K + + ++R R A + +S +RSRSSS+SSS SS+ST SSSGSSSSS SS S S
Sbjct: 49 TKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGS 108
Query: 606 SSSS-SSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTS 658
SS+S SSS+S SS S S + RSRS+ + RD K +RKRR S
Sbjct: 109 SSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEK-----ERKRRSPS 157
Score = 62.4 bits (150), Expect = 1e-09
Identities = 51/154 (33%), Positives = 71/154 (46%), Gaps = 13/154 (8%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
S +K K RS + + R+K K ++ SS T +SS S S+ SRSSS+SSS
Sbjct: 27 SPTKRKDRSDEKSKDRSK-DKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSS 85
Query: 612 -------STSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTS-----G 659
S+SGSSS +SS + SSS SRS S RR D +RR S
Sbjct: 86 GSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPK 145
Query: 660 LERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISE 693
+ + + S + TK + +R+ K I E
Sbjct: 146 RDEKERKRRSPSPKPTKVHIGRLTRNVTKDHIME 179
Score = 58.9 bits (141), Expect = 2e-08
Identities = 51/157 (32%), Positives = 71/157 (45%), Gaps = 32/157 (20%)
Query: 554 SKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSST 613
S TK + RS +++++ SK + + SS + S+SSGSSS+RS SSS+SS+
Sbjct: 27 SPTKRKDRSDEKSKDR-SKDKGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSSSTSSS 85
Query: 614 SGSSSRDSSS-STSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSS 672
S+S SSS S+SSS+ SRS S S RS SS S
Sbjct: 86 GSSTSTGSSSGSSSSSASSRSGS----------------------SSTSRSSSSSSSSGS 123
Query: 673 RDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRK 709
+ N R R +S K R E++RK
Sbjct: 124 PSPSRRRHDNRRRSRSKS--------KPPKRDEKERK 152
Score = 48.5 bits (114), Expect = 2e-05
Identities = 45/137 (32%), Positives = 57/137 (41%), Gaps = 8/137 (5%)
Query: 584 SSSSTSSSSGSSSSSGSSSSRSSSSSS-SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNR 642
S S G ++ SS+R+ S + S S+D S ++ ES + RGR R
Sbjct: 4 SGVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTR 63
Query: 643 DRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISES-SRSGKRS 701
R S R RS +S GSS T S +S S RS S S SRS S
Sbjct: 64 KRHSASSGSSSTR-----SRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSS 118
Query: 702 SRSERDRKSDRK-DKRR 717
S S S R+ D RR
Sbjct: 119 SSSGSPSPSRRRHDNRR 135
Score = 47.4 bits (111), Expect = 5e-05
Identities = 42/152 (27%), Positives = 64/152 (42%), Gaps = 14/152 (9%)
Query: 567 RNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTS 626
+ KS +R+ S + S S S G++ + SS + R S+SS S
Sbjct: 15 KENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGAT--KESSEKDRGRDKTRKRHSASSGS 72
Query: 627 SSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSD 686
SS+ SRS S + +SG S SS+ GSS ++ S +S S
Sbjct: 73 SSTRSRSSSTSSSGS---------STSTGSSSGSSSSSASSRSGSSSTSRSS--SSSSSS 121
Query: 687 RKRSISESSRSGKRSSRSE-RDRKSDRKDKRR 717
S S +R SRS+ + K D K+++R
Sbjct: 122 GSPSPSRRRHDNRRRSRSKSKPPKRDEKERKR 153
Score = 33.9 bits (76), Expect = 0.54
Identities = 28/80 (35%), Positives = 38/80 (47%), Gaps = 7/80 (8%)
Query: 503 EDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRS 562
E + VL P P+ T + P R+ P + L P + P +S + RSRS
Sbjct: 232 EITATVVLAPWPRPTPRR--FSPPRRMLPPPPMWLRSPPRMRRRSRSPRRRSPVRRRSRS 289
Query: 563 RGRARNKTSKSRSRSSSSSS 582
GR R+ RSRSSS+SS
Sbjct: 290 PGRRRH-----RSRSSSNSS 304
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 86.7 bits (213), Expect = 7e-17
Identities = 140/655 (21%), Positives = 257/655 (39%), Gaps = 106/655 (16%)
Query: 79 LEGAVSRLGGERRTRRESRQE---SDPEDDDV-KKPALQSSVVATSKERT-RRDLIQDQN 133
L+ + R +R + E+ E S+ E+++V ++ SS+V E T RRD ++ Q
Sbjct: 302 LKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTLRRDFLRLQQ 361
Query: 134 MDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQ---EIEQKLEVQAEEERKQVEN 190
+++ + RR Q+ QE + + + +RQ E ++++E Q E+ R+ E
Sbjct: 362 ENKERSEALRR---------QQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQ 412
Query: 191 ERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCP 250
+RRE E RR ++ E R EQ+
Sbjct: 413 QRRER-EARRQQEREQRRREQE-------------------------------------- 433
Query: 251 ATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEG 310
++ +EE +R+ E RR E ++ + E R+ ++E++ + ++Q +++
Sbjct: 434 -EKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAM 492
Query: 311 KVAQREEELEETGNQHNDVE-IEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEE 369
+ R E+EE H E ++ ++E+ + + D + + Q+ + +
Sbjct: 493 LLECRWREMEE----HRQAERLQRQLQQEQAYLLSLQHDHRRPHPQHSQQPPPPQQERSK 548
Query: 370 TEVRESEKQQDSQP-EEVMDVLEMVENVKHVIADQEVMETNRV-ESVEPSENEA-----S 422
E + +P + +V + H + + +T RV E PS +E+ S
Sbjct: 549 PSFHAPEPKAHYEPADRAREVEDRFRKTNHSSPEAQSKQTGRVLEPPVPSRSESFSNGNS 608
Query: 423 KELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQP 482
+ + P ++ EP + L+ K NVS + + S+P P+ A +SQ
Sbjct: 609 ESVHPALQRPAEPQVQWSHLASLKNNVSPV-------SRSHSFSDPSPK-FAHHHLRSQD 660
Query: 483 QLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQV-TQEQGHLLPERKDFPVESVKLTEVP 541
P +S+ SQ D PT + ++ +P R PV + +
Sbjct: 661 PC-------PPSRSEVLSQSSDSKSEAPDPTQKAWSRSDSDEVPPR--VPVRTTSRS--- 708
Query: 542 VEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSS 601
PVL+ +S + + S+ RN TS R S SS SS S
Sbjct: 709 --PVLS-RRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSG 765
Query: 602 SSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKH------------RRS 649
S S S S SG R SSS S S S+ D+K +
Sbjct: 766 SQPGSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFRPLKPAGEVDLTA 825
Query: 650 VDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRS 704
+ ++ R + HK + SS + G+ D+ D ++ ++ S SG +R+
Sbjct: 826 LAKELRAVEDVRPPHKVTDYSSSSEESGTTDEED-DDVEQEGADESTSGPEDTRA 879
Score = 68.2 bits (165), Expect = 3e-11
Identities = 101/462 (21%), Positives = 186/462 (40%), Gaps = 38/462 (8%)
Query: 280 KMEARPRRQSMKEKEHQVVRNEEQKAEQEEGK---VAQREEELEETGNQHNDVEIEEAGE 336
+ E + R ++++ ++ + E+Q EQEE K +A+R++ +E+ Q +E E+
Sbjct: 360 QQENKERSEALRRQQ---LLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLE-EQQRR 415
Query: 337 EEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQ---DSQPEEVMDVLEMV 393
E E +EQEE+ + +E+E + +EE E R +E+++ + + E + LE
Sbjct: 416 EREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEE 475
Query: 394 ENVKHVIADQEVMETNRVESVEPSENE-------ASKELEPEMEFEIEPDKECKSLSPGK 446
+ V+ Q + E + E E ++L+ E + + + + P
Sbjct: 476 QRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQH 535
Query: 447 ENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLS 506
+++ K S PEP A +P + + +++ + + S P +Q +
Sbjct: 536 S-----QQPPPPQQERSKPSFHAPEPKAHYEPADRAR-EVEDRFRKTNHSSPEAQSKQTG 589
Query: 507 LAVLQPTPQVTQ-------EQGHLLPERKDFP-VESVKLTEVP--VEPVLTVHPESKSKT 556
+ P P ++ E H +R P V+ L + V PV H S
Sbjct: 590 RVLEPPVPSRSESFSNGNSESVHPALQRPAEPQVQWSHLASLKNNVSPVSRSHSFSDPSP 649
Query: 557 KTRSRSRGRARNKTSKSRSRSSSSSSSSSSST---SSSSGSSSSSGSSSSRSSSSSSSST 613
K + R+++ SRS S SS S S + + S S S R ++S +
Sbjct: 650 KF-AHHHLRSQDPCPPSRSEVLSQSSDSKSEAPDPTQKAWSRSDSDEVPPRVPVRTTSRS 708
Query: 614 SGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSR 673
S RDS S S++ R + + + K G S SS GS
Sbjct: 709 PVLSRRDSPLQGSGQQNSQAGQRNSTSSIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQP 768
Query: 674 DT-KGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKD 714
+ GS+ + R RS S+S S + + + D+K+
Sbjct: 769 GSHPGSQSGSGERFRVRSSSKSEGSPSQRLENAVKKPEDKKE 810
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 86.3 bits (212), Expect = 9e-17
Identities = 61/141 (43%), Positives = 75/141 (53%), Gaps = 10/141 (7%)
Query: 551 ESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS 610
E + K +S R R+++++S SRS S SSS SSS S S S SSSS S SRSSS
Sbjct: 189 EEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRER 248
Query: 611 SSTSGSSSRDSSSSTSSSSESRSRSRGRGHN---RDRKHRR-----SVDRKRRDTSGL-- 660
S + GS SR SS S SS R RS + R+RK R S DRK+R T
Sbjct: 249 SRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSP 308
Query: 661 ERSHKSSKGGSSRDTKGSKDK 681
ER H+SS G S ++ S K
Sbjct: 309 ERRHRSSSGSSHSGSRSSSKK 329
Score = 83.2 bits (204), Expect = 8e-16
Identities = 63/143 (44%), Positives = 76/143 (53%), Gaps = 7/143 (4%)
Query: 566 ARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSST 625
+ K S RSRS S SS S SS+ SSS SSS S S S SSSSS S S SSSR+ S S
Sbjct: 193 SNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSR 252
Query: 626 SSSSESRSRS-RGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSR 684
S S S SRS RG R R + S R+ R S+ SS D K + ++
Sbjct: 253 GSKSRSSSRSHRGSSSPRKRSYSSSSSSPERN-----RKRSRSRSSSSGDRKKRRTRSRS 307
Query: 685 SDRK-RSISESSRSGKRSSRSER 706
+R+ RS S SS SG RSS ++
Sbjct: 308 PERRHRSSSGSSHSGSRSSSKKK 330
Score = 73.9 bits (180), Expect = 5e-13
Identities = 57/152 (37%), Positives = 72/152 (47%), Gaps = 7/152 (4%)
Query: 568 NKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSS 627
+K + S + +S S+ S+ RS S S SS S SSSR SS+ S
Sbjct: 165 SKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSR---SSSPS 221
Query: 628 SSESRSRSRGRGHNRDRKHRRSVDRKR-RDTSGLERSHKSSKGGSSRDTKGSKDKNSRS- 685
SS SRSRSR R + + RS R+R R RS S GSS K S +S S
Sbjct: 222 SSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSP 281
Query: 686 --DRKRSISESSRSGKRSSRSERDRKSDRKDK 715
+RKRS S SS SG R R R R +R+ +
Sbjct: 282 ERNRKRSRSRSSSSGDRKKRRTRSRSPERRHR 313
Score = 37.7 bits (86), Expect = 0.037
Identities = 29/123 (23%), Positives = 42/123 (34%), Gaps = 1/123 (0%)
Query: 593 GSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDR 652
G + S S D S E + +N D ++
Sbjct: 136 GKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNK 195
Query: 653 KRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDR 712
K+ + +S S SSR + S ++ R RS S SS+S RSS ER R
Sbjct: 196 KKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRS-SSSSQSRSRSSSRERSRSRGS 254
Query: 713 KDK 715
K +
Sbjct: 255 KSR 257
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 86.3 bits (212), Expect = 9e-17
Identities = 113/442 (25%), Positives = 172/442 (38%), Gaps = 75/442 (16%)
Query: 302 EQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQE 361
++ +E E+ K+A+++ + T E+E+A E+ E+E E EEE E
Sbjct: 146 QRPSEDEKKKLAEKKASIGYTYEDSTVAEVEKAAEKPEEE--------ESAAEEESNSDE 197
Query: 362 MEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEA 421
EV + + EV E Q E+V D+ + + +AD + + R + E +
Sbjct: 198 DEVIPDIDVEVDVDELNQ----EQVADLNKQATT--YGMADGDFVRMLRKDKEEAEAIKH 251
Query: 422 SKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQ-PQPQS 480
+K LE E K++ G+ + +E EK + + P A+ P
Sbjct: 252 AKALEEE-----------KAMYSGRRSRR---QRREFREKRLRGRKISPPSYARRDSPTY 297
Query: 481 QPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEV 540
P + S+S +S+ S PTP ++ + +
Sbjct: 298 DPYKRSPSESSSESRSRSRS-----------PTPGREEKITFITSFGGSDEEAAAAAAAA 346
Query: 541 PVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGS 600
V T P + + + R + + S S S SSS+S +SSS +SS S S S G
Sbjct: 347 AASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGG 406
Query: 601 S---SSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHN---------------- 641
S R + S S S S S SR S SRSRSRGR H+
Sbjct: 407 GYYRSGRHARSRSRSWSRSRSR-------SRRYSRSRSRGRRHSGGGSRDGHRYSRSPAR 459
Query: 642 --------RDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISE 693
R R S DR RR GL R H SS+ SS S+ ++ R S S
Sbjct: 460 RGGYGPRRRSRSRSHSGDRYRRGGRGL-RHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSP 518
Query: 694 SSRSGKRSSRSERDRKSDRKDK 715
S + SRS+ S ++K
Sbjct: 519 SQSRSRSRSRSQSPSPSPAREK 540
Score = 48.1 bits (113), Expect = 3e-05
Identities = 46/174 (26%), Positives = 74/174 (42%), Gaps = 8/174 (4%)
Query: 552 SKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSS 611
S+S + R R GR S SRSRSS S S S S + + S S S S S S S S S
Sbjct: 471 SRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQ 530
Query: 612 STSGSSSRD------SSSSTSSSSESRSRSRGRGHNRDRKHRRSVDR-KRRDTSGLERSH 664
S S S +R+ +S + + + G+ + ++ K R L R
Sbjct: 531 SPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQF 590
Query: 665 KS-SKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR 717
K+ K + + ++ R D R+++ R +R R + + +R+ R+
Sbjct: 591 KADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQ 644
Score = 30.8 bits (68), Expect = 4.6
Identities = 15/76 (19%), Positives = 37/76 (48%)
Query: 164 TERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWN 223
T ++K + +++ L Q + ++K + + + ER+ ++ ELR + +K+ + + +
Sbjct: 573 TPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREK 632
Query: 224 EHNAKIIKYIRTKTKP 239
E +Y R P
Sbjct: 633 EREEWERQYSRQSRSP 648
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 85.9 bits (211), Expect = 1e-16
Identities = 149/651 (22%), Positives = 248/651 (38%), Gaps = 87/651 (13%)
Query: 135 DEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQ----EIEQKLEVQAEEERK---Q 187
D KG++ RR L L K + ER++R + E+E+ +E Q EE++ +
Sbjct: 35 DYKGEEELRR----LEAALVKRPNPDILDHERKRRVELRCLELEEMMEEQGYEEQQIQEK 90
Query: 188 VENERRELFEE------RRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHL 241
V R L E+ + + + + +LA+L E+ NE +R
Sbjct: 91 VATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNER-------LRAAFGISD 143
Query: 242 FYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNE 301
Y+ G ++ E Q + E + P+++ K+K+ + R+E
Sbjct: 144 SYVDGSSFDPQRRAREAKQPAPEPPKPYSLVR--ESSSSRSPTPKQKKKKKKKDRGRRSE 201
Query: 302 EQKAEQEEGKVAQR-----EEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEE 356
+E K +++ E E ++ ++ + + ++++++ + + A K +
Sbjct: 202 SSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAH 261
Query: 357 EQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEP 416
+ + R + + + + D E + P
Sbjct: 262 RSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRP 321
Query: 417 SENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEP-------- 468
S E + + +P +E + DK+ K S + + S E+ S E P
Sbjct: 322 SSPETATK-QPSSPYE-DKDKDKKEKSATRPSPSP---ERSSTGPEPPAPTPLLAERHGG 376
Query: 469 QPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDL----SLAVLQPTPQVTQEQGHL- 523
P+P+A P SQ + S++ P PP PE L S P+PQ T+ H
Sbjct: 377 SPQPLA-TTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHAS 435
Query: 524 ----LPERKDFPVESVKLTEVPVEPVLT--------VHPESKSKTKTRSRS-----RGRA 566
P+ P +++ P + H + S+ RSRS RGR+
Sbjct: 436 SSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRS 495
Query: 567 RNKT----SKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSS-------SRSSSSSSSSTSG 615
R++T SRSRS S S+ S S G S SRS ++ S
Sbjct: 496 RSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSR 555
Query: 616 SSSRDSSSSTSSSSESRSRSR---GRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSS 672
S+ R S S S ++ RSRSR RG +R R R R R T RS ++ G S
Sbjct: 556 SARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRS 615
Query: 673 RD-TKGSKDKNSRSD---RKRSISESSRSGKRSSR--SERDRKSDRKDKRR 717
R T + +RS R RS S + RSG+ SR + R R R RR
Sbjct: 616 RSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARR 666
Score = 81.3 bits (199), Expect = 3e-15
Identities = 83/257 (32%), Positives = 111/257 (43%), Gaps = 37/257 (14%)
Query: 470 PEPVAQPQPQS----QPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLP 525
P QP + QP + +S S S S S + + +G LP
Sbjct: 2510 PASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLP 2569
Query: 526 ERKDFPVESVKL-TEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSS 584
+ + ++ V T P E V P + K K RS SSSSSSSS
Sbjct: 2570 VQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKR-------------KRRSSSSSSSSSS 2616
Query: 585 SSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDR 644
SSS+SSSS SSSSS SSSS SSSSSSSS+S S S + + + G R R
Sbjct: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSR 2676
Query: 645 KHRRSVD-------------RKRRDT---SGLERSHKSSKGGSSRDTKGSKDKNSRSDRK 688
R+ +D +RR + S ++ SS+ GS R +G D S S ++
Sbjct: 2677 SPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRG--DSRSPSHKR 2734
Query: 689 RSISESSRSGK-RSSRS 704
R + S R + RSSRS
Sbjct: 2735 RRETPSPRPMRHRSSRS 2751
Score = 75.9 bits (185), Expect = 1e-13
Identities = 95/338 (28%), Positives = 128/338 (37%), Gaps = 69/338 (20%)
Query: 436 DKECKSLSPGKENVSALDMEKESEEKEEKESEPQPE--PVAQPQPQSQPQLQLQSQSQPV 493
D+ P + S + E+ P P AQ QP+S QS+ +
Sbjct: 2403 DRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCL 2462
Query: 494 L-QSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPES 552
+ Q+ P + + LS + T + +L P V ++V P T +
Sbjct: 2463 IAQTTPVAGSQSLSSGAVATTTSSAGDHNGML----SVPAPGVPHSDVGEPPASTGAQQP 2518
Query: 553 KSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSS--------- 603
+ + R+ S SSSSSSSSSSS+SSSS SSSSSGSSSS
Sbjct: 2519 SALAALQPAKERRS--------SSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPV 2570
Query: 604 ----------------------------------RSSSSSSSSTSGSSSRDSSSSTSSSS 629
R SSSSSSS+S SSS SSSS+SSSS
Sbjct: 2571 QPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS 2630
Query: 630 ESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKD----KNSRS 685
S S S + S + S K G R K ++SRS
Sbjct: 2631 SSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRS 2690
Query: 686 ------DRKRSISESSRSGKRSSRSER-DRKSDRKDKR 716
+R+R + S ++SS SER R+ R D R
Sbjct: 2691 LSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSR 2728
Score = 68.6 bits (166), Expect = 2e-11
Identities = 86/343 (25%), Positives = 133/343 (38%), Gaps = 40/343 (11%)
Query: 400 IADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESE 459
+A + + +R S + + + S + E + PD + K+ +P L S
Sbjct: 1528 VARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTP-------LRQRSRSG 1580
Query: 460 EKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQE 519
E +S+ + P + + S P+++ + ++ P QS S PE + P P+
Sbjct: 1581 SSPEVDSKSRLSP-RRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKA-----PAPRALPR 1634
Query: 520 Q---GHLLPERKDFPVESVKLTEVPVEPVLT--------VHPESKSKTKTRSRSRGR--- 565
+ G R P S P P + PE K+K++T R R
Sbjct: 1635 RSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSS 1694
Query: 566 ---ARNKTSKSRSRSSSSSSSSSSST--------SSSSGSSSSSGSSSSRSSSSSSSSTS 614
R RSRS+SSS + S T S SS + SS R S+SS T
Sbjct: 1695 PELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTK 1754
Query: 615 GSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRD 674
+S R S S RSRSR R RR + TS R S+ +R
Sbjct: 1755 TTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTS-RRRQRSRSRSRVTRR 1813
Query: 675 TKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR 717
+G +SRS ++ S +S S +R RS S ++ + R
Sbjct: 1814 RRGGSGYHSRSPARQESSRTS-SRRRRGRSRTPPTSRKRSRSR 1855
Score = 66.6 bits (161), Expect = 8e-11
Identities = 63/179 (35%), Positives = 83/179 (46%), Gaps = 27/179 (15%)
Query: 552 SKSKTKTRSRSR-------GRARNKTS---KSRSRSSSSSSSSSSSTSSSSGSSSSS--- 598
S+S+T TR RSR GR+R++T +SR+RS S S S + SG S S
Sbjct: 594 SRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPA 653
Query: 599 --GSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRG----RGHNRD-------RK 645
G S SR+ + S S + +R S S S + R RSR RG +R R
Sbjct: 654 RRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRS 713
Query: 646 HRRSVDRKRRDTSGLERSHKS-SKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSR 703
H R+ R+ R S ER +KS + SR + K SR +RS S SS K SR
Sbjct: 714 HSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772
Score = 62.8 bits (151), Expect = 1e-09
Identities = 59/182 (32%), Positives = 83/182 (45%), Gaps = 29/182 (15%)
Query: 552 SKSKTKTRSRS---------------RGRARNKT---SKSRSRSSSSSSSSSSSTSSSSG 593
S++ + RSRS RGR+R++T +SR+RS S S S + SG
Sbjct: 586 SRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSG 645
Query: 594 SSSS-----SGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRR 648
S S G S SR+ + S S + +R S S S + R RSR R R R R
Sbjct: 646 RSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSR 705
Query: 649 SVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDR 708
S+ R+ R S + + GSS + K SR+ ++RS S SS K+S S R
Sbjct: 706 SLVRRGRSHS--RTPQRRGRSGSSSERK----NKSRTSQRRSRSNSSPEMKKSRISSRRS 759
Query: 709 KS 710
+S
Sbjct: 760 RS 761
Score = 62.4 bits (150), Expect = 1e-09
Identities = 96/448 (21%), Positives = 164/448 (36%), Gaps = 38/448 (8%)
Query: 302 EQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQE 361
E KA + + R E N+ + E +G E + V ++ QE
Sbjct: 1485 EPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQE 1544
Query: 362 MEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEA 421
++VK + R + DS P+ + + EV +R+ S S + +
Sbjct: 1545 LDVKPSASPQERS---ESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRL-SPRRSRSGS 1600
Query: 422 SKELE------PEMEFEIEPDKECKSLSP------GKENVSALDMEKESEEKEEKESEPQ 469
S E++ P + + E K+ +P + S+ E ES P+
Sbjct: 1601 SPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPE 1660
Query: 470 PEP---VAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVL----QPTPQVTQEQGH 522
P A+ +S P+ + +S++ P +S S PE A L + + +
Sbjct: 1661 HPPKSRTARRGSRSSPEPKTKSRTPPRRRSSR-SSPELTRKARLSRRSRSASSSPETRSR 1719
Query: 523 LLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSR------------SRGRARNKT 570
P + P S S +TKT SR R R+R++
Sbjct: 1720 TPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRR 1779
Query: 571 SKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSE 630
K+R+ S SS STS S S + R S + + ++SS ++S
Sbjct: 1780 EKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRR 1839
Query: 631 SRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSR-DTKGSKDKNSRSDRKR 689
RSR+ R R KR + +H+ S+ + + S+ + S R+R
Sbjct: 1840 GRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRR 1899
Query: 690 SISESSRSGKRSSRSERDRKSDRKDKRR 717
S S +S + +R SRS S R+ + R
Sbjct: 1900 SRSRTSVT-RRRSRSRASPVSRRRSRSR 1926
Score = 61.6 bits (148), Expect = 2e-09
Identities = 82/326 (25%), Positives = 115/326 (35%), Gaps = 46/326 (14%)
Query: 434 EPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPV-----AQPQPQSQPQLQLQS 488
EP SP ++ EK + + S P P+P A P+S P+
Sbjct: 389 EPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPES-PKPAPAP 447
Query: 489 QSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTV 548
S + S P S+ A + T + R P + + P
Sbjct: 448 GSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRM---GRSRSPATAKRGRSRSRTPTKRG 504
Query: 549 HPESKSKTKTRSRSR---GRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSS--GSSSS 603
H S+S RSRS GR+R+ + RSRS S S + G S S+ G S S
Sbjct: 505 HSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHS 564
Query: 604 RSSSSSSSSTSGSSSRDSSSSTSSSSESRSR-------------------------SRGR 638
RS ++ S S + +R S + + + RSR +R R
Sbjct: 565 RSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRR 624
Query: 639 GHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNS-------RSDRKRSI 691
R RRS R SG RS ++ G SR ++ S RS R RS
Sbjct: 625 SRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSR 684
Query: 692 SESSRSGKRSSRSERDRKSDRKDKRR 717
+ + R RS R R R RR
Sbjct: 685 TPARRGRSRSRTPRRGRSRSRSLVRR 710
Score = 61.2 bits (147), Expect = 3e-09
Identities = 74/325 (22%), Positives = 127/325 (39%), Gaps = 25/325 (7%)
Query: 413 SVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEP 472
S E S K P+ + KS +P + S + S E K +
Sbjct: 1654 STESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSS-----RSSPELTRKARLSRRSR 1708
Query: 473 VAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSL---AVLQPTPQVTQEQGHL-LPERK 528
A P+++ + + + P + S P++ S + P + T +G P+ +
Sbjct: 1709 SASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPR 1768
Query: 529 DFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSR-------SRSSSSS 581
+ S++ +R R R R+R++ ++ R SRS +
Sbjct: 1769 GLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQ 1828
Query: 582 SSSSSSTSSSSGSSSSSGSSSSRSSSSSS--------SSTSGSSSRDSSSSTSSSSESRS 633
SS +S+ G S + +S RS S +S S S ++ R S S T S RS
Sbjct: 1829 ESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRS 1888
Query: 634 RSRGRGHNRDR-KHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSIS 692
RSR +R R + R SV R+R + S + S+ + T+ + + R+RS S
Sbjct: 1889 RSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRS 1948
Query: 693 ESSRSGKRSSRSERDRKSDRKDKRR 717
+ +R SRS + R+ + R
Sbjct: 1949 RTPPVTRRRSRSRTPPVTRRRSRSR 1973
Score = 58.5 bits (140), Expect = 2e-08
Identities = 56/173 (32%), Positives = 85/173 (49%), Gaps = 13/173 (7%)
Query: 553 KSKTKTRSRSRGRARNKT-SKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSS- 610
+S+++T +R RGR+R++T ++ RSRS + + S S + + S S + + R S + S
Sbjct: 572 RSRSRTPAR-RGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSP 630
Query: 611 ---SSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSS 667
S S S +R S S S + R RSR R R + R +R SG RS +
Sbjct: 631 VRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARR---SGRSRSRTPA 687
Query: 668 KGGSSRDTKGSKDKN-SRSDRKRSISES---SRSGKRSSRSERDRKSDRKDKR 716
+ G SR + ++ SRS +R S S R G+ S SER KS +R
Sbjct: 688 RRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRR 740
Score = 54.7 bits (130), Expect = 3e-07
Identities = 60/199 (30%), Positives = 85/199 (42%), Gaps = 13/199 (6%)
Query: 527 RKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRS---RGRARNKTSKSRSRSSSSSSS 583
R P T PV ++ ++RSR+ RGR+R++T R RS S + +
Sbjct: 616 RSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPA 675
Query: 584 SSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRD 643
S S S + + G S SR+ S + R S S + RS G R
Sbjct: 676 RRSGRSRSR-TPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRS---GSSSERK 731
Query: 644 RKHRRSVDRKRRDTS-GLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSS 702
K R S R R ++S +++S SS+ S + SK K SR +RS+S SS K+ S
Sbjct: 732 NKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAK-SRLSLRRSLSGSSPCPKQKS 790
Query: 703 ----RSERDRKSDRKDKRR 717
R R S K K R
Sbjct: 791 QTPPRRSRSGSSQPKAKSR 809
Score = 54.3 bits (129), Expect = 4e-07
Identities = 44/155 (28%), Positives = 71/155 (45%), Gaps = 11/155 (7%)
Query: 550 PESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSS 609
P + ++++R+ RGR+R+++ R RS S + + SSS + S +S RS S+S
Sbjct: 686 PARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNS 745
Query: 610 SSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKG 669
S SR SS + S S RS++ K R S+ R +S + +
Sbjct: 746 SPEM--KKSRISSRRSRSLSSPRSKA---------KSRLSLRRSLSGSSPCPKQKSQTPP 794
Query: 670 GSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRS 704
SR SR+ +RS S SS K+ S++
Sbjct: 795 RRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKT 829
Score = 54.3 bits (129), Expect = 4e-07
Identities = 52/175 (29%), Positives = 81/175 (46%), Gaps = 8/175 (4%)
Query: 550 PESKSKTKTRSRSRGRARNKT---SKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSS 606
P +S+++ + R+R++T S+ RSRS +S S S S +S + S S +S S
Sbjct: 1860 PWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVS 1919
Query: 607 SSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVD----RKRRDTSGLER 662
S S + +R S S + ++ RSRSR R R R+ R R TS + R
Sbjct: 1920 RRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITR 1979
Query: 663 SHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR 717
S+ S + S+ + S R+RS S +S +R SRS R+ + R
Sbjct: 1980 RRSRSRT-SPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSR 2033
Score = 52.4 bits (124), Expect = 1e-06
Identities = 86/361 (23%), Positives = 125/361 (34%), Gaps = 30/361 (8%)
Query: 354 EEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVES 413
E E K++M + +E+ ++ P V D E K + + S
Sbjct: 1160 ETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSS 1219
Query: 414 VEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEP- 472
E E ++ + E +E + KS P + +S L E + ES P+ E
Sbjct: 1220 PETKEQNSALPTSSQDEELMEVVE--KSEEPAGQILSHLSSELKEMSTSNFESSPEVEER 1277
Query: 473 --VAQPQPQSQPQLQLQSQSQPVLQSQ---PPSQPEDLSLAVLQPTPQVTQEQGHLLPER 527
V+ QSQ Q L++ P + S P PE L+ +P G L R
Sbjct: 1278 PAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELS---NSPLRENSFGSPLEFR 1334
Query: 528 KDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSS 587
P L + ++ + G N+ S S+ SS
Sbjct: 1335 NSGP--------------LGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSG 1380
Query: 588 TSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHR 647
SSS S + + S+ S SS + R S SSS+ S G R+ R
Sbjct: 1381 HSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSR 1440
Query: 648 RSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERD 707
RD SG H S GSS G KD R RS +SS K ++ R
Sbjct: 1441 SGSSPGLRDGSGTPSRH--SLSGSS---PGMKDIPRTPSRGRSECDSSPEPKALPQTPRP 1495
Query: 708 R 708
R
Sbjct: 1496 R 1496
Score = 51.6 bits (122), Expect = 2e-06
Identities = 57/179 (31%), Positives = 80/179 (44%), Gaps = 18/179 (10%)
Query: 553 KSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSS---S 609
+S+++T SR R+R++TS +R RS S +S S S S + S SR+ ++ S
Sbjct: 1887 RSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRS 1946
Query: 610 SSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVD----RKRRDTSGLERSHK 665
S T + R S S T + RSRSR R R R+ R R TS + R
Sbjct: 1947 RSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRS 2006
Query: 666 SSKGG------SSRDTKGSKDKNSRS-----DRKRSISESSRSGKRSSRSERDRKSDRK 713
S+ S T + + SRS RKRS S S + +R SRS R + K
Sbjct: 2007 RSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGK 2065
Score = 51.2 bits (121), Expect = 3e-06
Identities = 87/369 (23%), Positives = 146/369 (39%), Gaps = 39/369 (10%)
Query: 369 ETEVRESEKQQDSQPEEVMDVLEMVEN-----VKHVIADQEVMETNRVESVEPSENEASK 423
ET+ + S SQ EE+M+V+E E + H+ ++ + M T+ ES E
Sbjct: 1221 ETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEER--- 1277
Query: 424 ELEPEMEFEIEPDKECKSLSPGK--ENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQ 481
P + ++ + SL + S+ S E +E + P E + +
Sbjct: 1278 ---PAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFR 1334
Query: 482 PQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTP------QVTQEQGHLLPERKDFPVESV 535
L ++ S+ L L+ P Q T+ GH E VE
Sbjct: 1335 NSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKA 1394
Query: 536 KLT--EVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSG 593
++ + PVL P + S+ ++ S S ++ ++ SR S S SS S +
Sbjct: 1395 GMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTP 1454
Query: 594 SS-SSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDR 652
S S SGSS + S G S DSS + ++ R R R + + + +
Sbjct: 1455 SRHSLSGSSPGMKDIPRTPS-RGRSECDSSPEPKALPQT-PRPRSRSPSSPELNNKCL-T 1511
Query: 653 KRRDTSGLERS-----------HKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRS 701
+R+ SG E S + S+ GSS++ K S S ++RS S+SS K
Sbjct: 1512 PQRERSGSESSVDQKTVARTPLGQRSRSGSSQEL---DVKPSASPQERSESDSSPDSKAK 1568
Query: 702 SRSERDRKS 710
+R+ ++S
Sbjct: 1569 TRTPLRQRS 1577
Score = 50.8 bits (120), Expect = 4e-06
Identities = 68/285 (23%), Positives = 110/285 (38%), Gaps = 21/285 (7%)
Query: 416 PSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQ 475
P NE S + FE PD E KS +P + + S S K S P P
Sbjct: 858 PQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSG------SSPPRVKSSTP---PRQS 908
Query: 476 PQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESV 535
P S PQ ++++ P +S S S + TP+ + R P +V
Sbjct: 909 PSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRS---------RSVSPCSNV 959
Query: 536 KLTEVP-VEPVLTVHPESKSKTKTRSR-SRGRARNKTSKSRSRSSSSSSSSSSSTSSSSG 593
+ +P + P++K K +T R S + + K ++++ S S S +
Sbjct: 960 ESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQE 1019
Query: 594 SSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRK 653
S S S S S + S+ S SS + + +S+ +R V +
Sbjct: 1020 KSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQS 1079
Query: 654 RRDTSGLE-RSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRS 697
++ L+ +S S KGG SR + + SRS ++ E S S
Sbjct: 1080 HSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSAS 1124
Score = 50.8 bits (120), Expect = 4e-06
Identities = 51/172 (29%), Positives = 68/172 (39%), Gaps = 11/172 (6%)
Query: 544 PVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSS 603
PV S++ TR RSR R +SRSR+ + S S + S +S
Sbjct: 1917 PVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSP 1976
Query: 604 RSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVD----RKRRDTSG 659
+ S S TS + R S S TS + RSRSR R R R+ R R T
Sbjct: 1977 ITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPL 2036
Query: 660 LERSHKSSKG-------GSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRS 704
L R S+ SR + ++ K S + +I S SG S RS
Sbjct: 2037 LPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRS 2088
Score = 49.7 bits (117), Expect = 9e-06
Identities = 48/177 (27%), Positives = 80/177 (45%), Gaps = 23/177 (12%)
Query: 552 SKSKTKTRSRS-----RGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSS 606
S++ + RSRS RGR+ ++T + R RS SSS + S +S S S+S +S
Sbjct: 694 SRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSR 753
Query: 607 SSSSSSTSGSSSRDSSSSTSS--------------SSESRSRSRGRGHNRDRKHRRSVDR 652
SS S S SS R + S S S++ R G ++ + R+ R
Sbjct: 754 ISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR 813
Query: 653 KRRDTSG---LERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSER 706
+ R +S ++S S+ S + K K+ R+ SI+ S ++ ++S +R
Sbjct: 814 RSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSIT-SPQANEQSVTPQR 869
Score = 48.1 bits (113), Expect = 3e-05
Identities = 48/163 (29%), Positives = 72/163 (44%), Gaps = 2/163 (1%)
Query: 556 TKTRSRSR-GRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTS 614
++ RSRSR A K S+SR+ ++ S S + S S S S SR S S +S +
Sbjct: 1848 SRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVT 1907
Query: 615 GSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRD 674
SR S +S S SRSR+ R R + R+ R + +S
Sbjct: 1908 RRRSR-SRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVT 1966
Query: 675 TKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR 717
+ S+ + S R+RS S +S +R SRS + R+ + R
Sbjct: 1967 RRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSR 2009
Score = 47.0 bits (110), Expect = 6e-05
Identities = 50/150 (33%), Positives = 62/150 (41%), Gaps = 11/150 (7%)
Query: 547 TVHPESKSKTK--TRSRSRGRARNKTSK-SRSRSSSSSSSSSSSTSSSSGSSSSSGSSSS 603
T S+S+T TR RSR R T + SRSR+S + S S +S S +S
Sbjct: 1941 TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP 2000
Query: 604 RSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRG----RGHNRDRK----HRRSVDRKRR 655
+ S S TS + R S S T + RSRSR R +R R RRS R R
Sbjct: 2001 VTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPR 2060
Query: 656 DTSGLERSHKSSKGGSSRDTKGSKDKNSRS 685
G +S R GS SRS
Sbjct: 2061 TARGKRSLTRSPPAIRRRSASGSSSDRSRS 2090
Score = 44.7 bits (104), Expect = 3e-04
Identities = 71/294 (24%), Positives = 106/294 (36%), Gaps = 36/294 (12%)
Query: 408 TNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESE 467
+ R S+ + PEM+ + +SLS + K + S
Sbjct: 728 SERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRS--------KAKSRLSLRRSL 779
Query: 468 PQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPER 527
P + + Q+ P+ SQP +S+ P + S + P P+ +
Sbjct: 780 SGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSS---PPPKQKSKTPSRQSHS 836
Query: 528 KDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSS 587
P VK P + +T P++ ++ T R + + +SR+ S S S SS
Sbjct: 837 SSSPHPKVKSGTPPRQGSIT-SPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSS 895
Query: 588 T----SSSSGSSSSSGSSSSRSS-----SSSSSSTSGSSSRDSSSSTSSSSESRSRSRGR 638
SS+ S S SSS + S S SGSSS S TS ++ RSRS
Sbjct: 896 PPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSP 955
Query: 639 GHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSIS 692
N + R + R S G SS DTK + R SIS
Sbjct: 956 CSNVE---SRLLPR------------YSHSGSSSPDTKVKPETPPRQSHSGSIS 994
Score = 40.0 bits (92), Expect = 0.008
Identities = 60/203 (29%), Positives = 75/203 (36%), Gaps = 35/203 (17%)
Query: 550 PESK----SKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSS--- 602
PE K S ++RS S R++ K+ S RS S SS S + S SGSS
Sbjct: 747 PEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKA 806
Query: 603 ------SRSSSSSSSSTSGSSSRDSSSSTSSSS-----ESRSRSRGRGHNRDRKHRRSVD 651
RS SSSS S S S SSSS +S + R + + +SV
Sbjct: 807 KSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVT 866
Query: 652 RKRR---------DTSGLERSHKSSKGGSSRDTKGS---KDKNSRSDR-----KRSISES 694
+RR + S S G S K S + SRS K IS
Sbjct: 867 PQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPR 926
Query: 695 SRSGKRSSRSERDRKSDRKDKRR 717
RS SS R + R RR
Sbjct: 927 QRSHSGSSSPSPSRVTSRTTPRR 949
Score = 36.6 bits (83), Expect = 0.083
Identities = 29/94 (30%), Positives = 45/94 (47%), Gaps = 5/94 (5%)
Query: 548 VHPESKSKTKTRSRSRGRARNKTS---KSRSRSSSSSSSSSSSTSSSSG--SSSSSGSSS 602
+ S+S+T R R R+R+ + +SRSR+ ++ S T S S+SGSSS
Sbjct: 2026 IRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSS 2085
Query: 603 SRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSR 636
RS S++ +T S + +SS SR
Sbjct: 2086 DRSRSATPPATRNHSGSRTPPVALNSSRMSCFSR 2119
Score = 34.3 bits (77), Expect = 0.41
Identities = 31/103 (30%), Positives = 47/103 (45%), Gaps = 3/103 (2%)
Query: 538 TEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSS 597
+ P+ P S + RSRSR + +S +RS + S+S SSS S S+
Sbjct: 2032 SRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSA 2091
Query: 598 SGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSES---RSRSRG 637
+ ++ S S + + +SSR S S S S + R RS G
Sbjct: 2092 TPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPG 2134
Score = 33.5 bits (75), Expect = 0.70
Identities = 123/630 (19%), Positives = 203/630 (32%), Gaps = 92/630 (14%)
Query: 53 GRGRGSLLLRRGFSDSGGGPPAKQRDLEGAVSRLGGERRT-------------RRESRQE 99
GR R RRG S S PA++R +R RT RR SR
Sbjct: 571 GRSRSRTPARRGRSRSR--TPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTR 628
Query: 100 SDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQRNR---RIFGLLMGTLQKF 156
S + + S + S+ RR + + +G+ R+R R G
Sbjct: 629 SPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPAR 688
Query: 157 KQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELA 216
+ S T R+ R + ++ Q E + +T R
Sbjct: 689 RGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPE 748
Query: 217 QLQEEWNEHNAKIIKYIRTKTKPHLFY---IPGRM-CPATQKLIEESQRKMNALFEGRRI 272
+ + ++ + R+K K L + G CP K + RR
Sbjct: 749 MKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCP-----------KQKSQTPPRRS 797
Query: 273 EFAEQINKMEAR-PRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEI 331
K ++R P R+S + + + Q + + T + +
Sbjct: 798 RSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITS 857
Query: 332 EEAGEEE--EKEIAIVHSDAEKEQEEEEQKQEM-----EVKMEEETEVRESEKQQDS-QP 383
+A E+ + + S + E + + +++ T R+S + S QP
Sbjct: 858 PQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQP 917
Query: 384 EEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKS-L 442
+ VK +I+ ++ + S PS + + P + P +S L
Sbjct: 918 K-----------VKAIISPRQRSHSG---SSSPSPSRVTSRTTPRRSRSVSPCSNVESRL 963
Query: 443 SP--GKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPP- 499
P S+ D + + E + P + + Q+ P L P Q +
Sbjct: 964 LPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKD 1023
Query: 500 ----SQPEDLSLA--VLQPTPQVTQEQGHLLPERKDFPVESVKL-----------TEVPV 542
S P LSL V TP P F V S++L ++
Sbjct: 1024 SLVQSCPGSLSLCAGVKSSTP----------PGESYFGVSSLQLKGQSQTSPDHRSDTSS 1073
Query: 543 EPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSS 602
V H ES S +S+ + K +SRS S + +S S G S+S
Sbjct: 1074 PEVRQSHSESPSL-----QSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLK 1128
Query: 603 SRSSSSSSSSTSGSSSRDSSSSTSSSSESR 632
S S S S SSS + S S +SR
Sbjct: 1129 SGMSPEQSRFQSDSSSYPTVDSNSLLGQSR 1158
Score = 30.8 bits (68), Expect = 4.6
Identities = 43/184 (23%), Positives = 70/184 (38%), Gaps = 26/184 (14%)
Query: 487 QSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVL 546
+S++ PV + + S+ TP VT+ + R P + + + P+
Sbjct: 1924 RSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRS-----RSRTPPVTRRRSRSRTSPIT 1978
Query: 547 TVHPESKSKTKTRSRSRGR--------ARNKTS-----KSRSRSSSSSSSSSSST----- 588
S++ TR RSR R +R++TS +SRSR+ + S S
Sbjct: 1979 RRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLP 2038
Query: 589 ---SSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRK 645
S S + S SR+ ++ S + S + S+S S RSR R
Sbjct: 2039 RKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRN 2098
Query: 646 HRRS 649
H S
Sbjct: 2099 HSGS 2102
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 84.3 bits (207), Expect = 3e-16
Identities = 143/691 (20%), Positives = 247/691 (35%), Gaps = 89/691 (12%)
Query: 75 KQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNM 134
K+RD E R + RE +E D E + ++ + +ER R + +
Sbjct: 721 KERDRERDRDR---DHDRERERERERDREKEREREREERERERERERERERERERERERA 777
Query: 135 DEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEI-EQKLEVQAEEERKQVENERR 193
E+ K+R R+ + ++ + +R+++R+EI E + +ERK + R
Sbjct: 778 RERDKERERQ---------RDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRN 828
Query: 194 ELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQ 253
E R R + ++ NE + + + +R + L P + Q
Sbjct: 829 EGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLS--PSHLTEDRQ 886
Query: 254 KLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKE-------------KEHQVVRN 300
+E RK RR E E K+ + +++ E HQ
Sbjct: 887 GRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDR 946
Query: 301 EEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHS----DAEKEQEEE 356
E +E K + ++ + +DV IE E E V S +K E++
Sbjct: 947 ETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKK 1006
Query: 357 EQKQEMEVKMEEETEVRESEKQQDSQPEEVM---DVLEMVENVKHVIADQEVMETNRVES 413
+K + + + +E ++S+K++ + + +++EM ++ D + E
Sbjct: 1007 RKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKE------ 1060
Query: 414 VEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPV 473
+ + ++ S E P+ E + + +PG S P P PV
Sbjct: 1061 -DTAFSDWSDEDVPDRTEVTEAEHTATATTPG------------STPSPLSSLLPPPPPV 1107
Query: 474 AQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQV-TQEQGHLLPERKDFPV 532
A + P + + + S T E H R V
Sbjct: 1108 ATATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTR--V 1165
Query: 533 ESVKLTEVPVEPVLTVHPESKSKTKT-------RSRSRGRARNKTSKSRSRSSSSSSSSS 585
E V+ V +E P + ++ + RS + GR R+ ++ S RS S
Sbjct: 1166 EKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRK 1225
Query: 586 SSTSSSSGSSSSSGS-----------------SSSRSSSSSSSSTSGSSSRDSSSSTSSS 628
S S + S SRS+SS + SSR SS +
Sbjct: 1226 RVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQ 1285
Query: 629 SESRSRS---RGRGHNRDR-KHRRSVDRKRRDTSGLERSHKSSKG---GSSRDTKGSKDK 681
SRS S R R RDR +H R +R+RRDT E + K RD +++
Sbjct: 1286 VHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERER 1345
Query: 682 NSRSDRKRSISESSRSGKRSSRSERDRKSDR 712
D++R + + R S ERDR DR
Sbjct: 1346 ERERDKRRDL-DRERERLISDSVERDRDRDR 1375
Score = 81.6 bits (200), Expect = 2e-15
Identities = 146/761 (19%), Positives = 285/761 (37%), Gaps = 145/761 (19%)
Query: 51 GGGRGRGSLLLRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKP 110
G RGR L +G S G Q D + S TR + + D +
Sbjct: 561 GRSRGRVPELPEKGSRGSRGS----QIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQ 616
Query: 111 ALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRR 170
A SS ER RRD + + R L ++ ++ V R +R
Sbjct: 617 ARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERA 676
Query: 171 QEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKII 230
+E +++ E E ER++ RE +ER ++ R E++ E + +E
Sbjct: 677 RERDRERERDRERERERERERDREREKERELERERAREREREREKERDRE---------- 726
Query: 231 KYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSM 290
R + + H R E + ++ + R R +
Sbjct: 727 ---RDRDRDH----------------------------DRERERERERDREKEREREREE 755
Query: 291 KEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKE-IAIVHSDA 349
+E+E + R E++ E+E + +R++E E + D E ++ G ++ +E + D
Sbjct: 756 RERERERERERERERERERERARERDKERE----RQRDWEDKDKGRDDRREKREEIREDR 811
Query: 350 EKEQEEEEQKQEMEVKMEEETEVRESEK-QQDSQPEEVMDVLEMVENVKHVIADQEVMET 408
+E+K + + E R+S K +++ P+ +N KH + Q V+
Sbjct: 812 NPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQ-VVRP 870
Query: 409 NRVESVEPS---ENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKE 465
S+ PS E+ + E + + E + KE VS++D ++E E E
Sbjct: 871 QESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESS 930
Query: 466 SEPQPEPVAQPQP---QSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGH 522
+ + Q ++ + +++ + +Q +P + ++ + + + + T E G
Sbjct: 931 RMRAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQ 990
Query: 523 LLPERKDFPVESV----------------------KLTEVPVEPVLTVHPE--------- 551
+ +K +S+ K P P +T E
Sbjct: 991 VFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKN 1050
Query: 552 -----SKSKTKTR----------SRSRGRARNKTSKSRSRSSSSSSSSS----------- 585
S+ K T R+ T+ + + S+ S SS
Sbjct: 1051 GILEDSQKKEDTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATA 1110
Query: 586 -SSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHN--- 641
++T ++ +++++ +++S S+S+ + STS + + ++++ ++ R R R
Sbjct: 1111 TATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVET 1170
Query: 642 -----RDRKHRRSVDRKRRDTSGLERSHKSSKGG---SSRDTKGSKDKNSRSDRKRSISE 693
D +HR+ +D+KR + G RS++S G S + + + +S RKR +
Sbjct: 1171 PHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHS 1230
Query: 694 SSR----------SGKRSSRSE--------RDRKSDRKDKR 716
SR +G+R SR + R SDR+D R
Sbjct: 1231 GSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSR 1271
Score = 75.5 bits (184), Expect = 2e-13
Identities = 131/685 (19%), Positives = 255/685 (37%), Gaps = 81/685 (11%)
Query: 74 AKQRDLEGAVSRLGGERRTRRESRQESDPEDD-DVKKPALQSSVVATSKERTR-RDLIQD 131
A++RD E R ER RE ++ + E + ++++ + KER R RD +D
Sbjct: 676 ARERDRERERDR---ERERERERERDREREKERELERERAREREREREKERDRERDRDRD 732
Query: 132 QNMD-EKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVEN 190
+ + E+ ++R+R ++E E ++R +E E++ E + E ER++
Sbjct: 733 HDRERERERERDR-------------EKEREREREERERERERERERERERERERERARE 779
Query: 191 ERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNA----KIIKYIRTKTKPHLFYIPG 246
+E +R + + +++ + +++E+ N + K K R + P P
Sbjct: 780 RDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPK 839
Query: 247 RMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVV------RN 300
R E +A G ++ RP+ H +
Sbjct: 840 RR--------REHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKE 891
Query: 301 EEQKAEQEEGKVAQREEELEE----TGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEE 356
E++K E++E E+EL+E Q EI E+ ++I H ++E +
Sbjct: 892 EDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDR 951
Query: 357 E----------QKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVM 406
QK+ ++ K E++ + + S+ +V + + K + ++
Sbjct: 952 AHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSP-KKGQKKKSIEKKRKKS 1010
Query: 407 ETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKES 466
+ + S E + ++ K+ P I +E + GK + +KE +
Sbjct: 1011 KGDSDISDEEAAQQSKKKRGPRTP-PITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSD 1069
Query: 467 EPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPE 526
E P+ + ++ + P S P LS ++L P P V +P
Sbjct: 1070 EDVPD-----------RTEVTEAEHTATATTPGSTPSPLS-SLLPPPPPVATATATTVPA 1117
Query: 527 R---------KDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARN-KTSKSRSR 576
F ++ ++ P T + ++ R R R +T
Sbjct: 1118 TLAATTAAAATSFSTSAITIS-TSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIE 1176
Query: 577 SSSSSSSSSSSTSSSSGSSSSSGSSSS---RSSSSSSSSTSGSSSRDSSSSTSSSSESRS 633
+ SSS GS+ S+ S +S RS S+ S+ SG S S R
Sbjct: 1177 DAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDRE 1236
Query: 634 RSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISE 693
+++ +RK R ++ + + S+ SSR + D+ S R S
Sbjct: 1237 KTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHS-RSGSFDS 1295
Query: 694 SSRSGKRSS-RSERDRKSDRKDKRR 717
R +R +R+R+ +R+D R+
Sbjct: 1296 RDRLQERDRYEHDRERERERRDTRQ 1320
Score = 72.8 bits (177), Expect = 1e-12
Identities = 101/420 (24%), Positives = 163/420 (38%), Gaps = 42/420 (10%)
Query: 320 EETGNQHNDVEIEEAGEEEEKEIAIVHSDAEK--EQEEEEQKQEMEVKMEEETEVRESEK 377
E N+ DV+ E E+ + V ++ + +E+E+ K E E E E E E
Sbjct: 87 ERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTPESEEENVEWET 146
Query: 378 QQDSQPEEVMD---VLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPEM-EFEI 433
+D ++ V E+ +K +E+M+ + + E KE+ PE+ ++
Sbjct: 147 NRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKL 206
Query: 434 EPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQ-P 492
P + S + S+ + S K+++++ P+ Q S+ QS+ + P
Sbjct: 207 SPSPSLRKSSKSPKRKSS--PKSSSASKKDRKTSAVSSPLLDQQRNSKTN---QSKKKGP 261
Query: 493 VLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPES 552
S PP PED++L G E+ + T + +
Sbjct: 262 RTPSPPPPIPEDIAL-------------GKKYKEKYKVKDRIEEKTRDGKDRGRDFERQR 308
Query: 553 KSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSS--- 609
+ + K RS S + SR SSSS S SS S S + S S + + +
Sbjct: 309 EKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLR 368
Query: 610 -SSSTSGSSSRDSSSSTSSSSESRSRSRGRG---HNR-----DRKHRRSVD----RKRRD 656
S+S S S S S RS R +G H R DR+H R D R R
Sbjct: 369 RSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREK 428
Query: 657 TSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKR 716
S ER ++ + SSRD + ++ DR+ + R R SR RD + R R
Sbjct: 429 DSREEREYEQDQS-SSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSR 487
Score = 56.2 bits (134), Expect = 1e-07
Identities = 113/665 (16%), Positives = 228/665 (34%), Gaps = 73/665 (10%)
Query: 90 RRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIFGLL 149
R++ + +++S P+ K ++S V++ + DQ + K Q ++ G
Sbjct: 213 RKSSKSPKRKSSPKSSSASKKDRKTSAVSSP--------LLDQQRNSKTNQSKKK--GPR 262
Query: 150 MGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLL 209
+ E ++ K + +++ ++E E+ + +R FE +R K+ + R
Sbjct: 263 TPSPPPPIPEDIALGKKYKEKYKVKDRIE-----EKTRDGKDRGRDFERQREKRDKPRST 317
Query: 210 ----EQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNA 265
+ ++ + + I+ R P P P+ Q+ + R+ +
Sbjct: 318 SPAGQHHSPISSRHHSSSSQSGSSIQ--RHSPSPRRKRTPS---PSYQRTLTPPLRRSAS 372
Query: 266 LFEGRRIEFAEQINKMEARPRRQS-MKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGN 324
+ + + + ++ PR +S M+EK R++ ++ Q + +R E+ +
Sbjct: 373 PYPSHSLSSPQ---RKQSPPRHRSPMREKG----RHDHERTSQSHDRRHERREDTRGKRD 425
Query: 325 QHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPE 384
+ D EE E+++ + H D + ++ +++ + + + E+R+S +DS+
Sbjct: 426 REKDSR-EEREYEQDQSSSRDHRDDREPRDGRDRRDARDTR--DRRELRDSRDMRDSR-- 480
Query: 385 EVMDVLEMVENVK-----------HVIADQEVMETNRVESVEPSEN-------------- 419
E+ D + + H D+E +T+R E P E+
Sbjct: 481 EMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSR 540
Query: 420 -EASKELEPEMEFEIEPDKECKSLS-----PGKENVSALDMEKESEEKEEKESEPQPEPV 473
E E E EI D+ +S P K + + + +S +
Sbjct: 541 TEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRS 600
Query: 474 AQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVT-QEQGHLLPERKDFPV 532
+ P+ P+ + Q++ + + + P + QG +D
Sbjct: 601 SYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERR 660
Query: 533 ESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSS 592
E ++ V + + + R R R R R + R R +
Sbjct: 661 EERRVDRVDDRRDERARERDRERERDRERERERERER---DREREKERELERERARERER 717
Query: 593 GSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDR 652
R RD E R R R R R+R+ R +R
Sbjct: 718 EREKERDRERDRDRDHDRERER-ERERDREKEREREREERERERERERERERERERERER 776
Query: 653 KRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDR 712
R ER RD + K + R DR R K+ R+E +
Sbjct: 777 ARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQ 836
Query: 713 KDKRR 717
KRR
Sbjct: 837 SPKRR 841
Score = 51.2 bits (121), Expect = 3e-06
Identities = 127/678 (18%), Positives = 241/678 (35%), Gaps = 98/678 (14%)
Query: 114 SSVVATSKERTRRDLIQD-----QNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQK 168
SS S ER DL + Q++D + ++RN + ++ES+ R+K
Sbjct: 71 SSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTE------ESSSPVRKESSRGRHREK 124
Query: 169 RRQEIEQKLEVQAEEERKQVENERREL----FEERRAKQTELRLLEQKV--ELAQLQEEW 222
+I ++ ++EEE + E R + + L + QK+ EL +L++E
Sbjct: 125 EDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQEN 184
Query: 223 NEHNAKII-------KYIRTKTKPHLFY-----IPGRMCPATQKLIEESQRKMNA----L 266
E +II + +R+K P P R + RK +A L
Sbjct: 185 MEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPL 244
Query: 267 FEGRRIEFAEQINKMEARPRR------------QSMKEKEHQVVRNEEQKAE-QEEGKVA 313
+ +R Q K R + KEK R EE+ + ++ G+
Sbjct: 245 LDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDF 304
Query: 314 QREEELEE-------TGNQHNDVEIEEAGEEEEKEIAIV-HSDAEKEQEEEEQKQEMEVK 365
+R+ E + G H+ + + +I HS + + + + +
Sbjct: 305 ERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLT 364
Query: 366 MEEETEVRESEKQQDSQPEEVMDVLE----MVENVKHVIADQEVMETNRVESVEPSENEA 421
S P+ M E +H R E E + +
Sbjct: 365 PPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKR 424
Query: 422 SKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQ 481
+E + E E E D+ S +++ + + ++ +++ + E + +
Sbjct: 425 DREKDSREEREYEQDQ-----SSSRDHRDDREPRDGRDRRDARDTRDRRE--LRDSRDMR 477
Query: 482 PQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKD-FPVESVK---- 536
+++ S+ +S+ P + +G ++D +P ES
Sbjct: 478 DSREMRDYSRDTKESRDPRDSRST-----RDAHDYRDREGRDTHRKEDTYPEESRSYGRN 532
Query: 537 -LTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKT-------------SKSRSRSSSSSS 582
L E + ++S+++ R+ GR+R + S+ S SS+S+
Sbjct: 533 HLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNY 592
Query: 583 SSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHN- 641
S T SS +R + SS RD + S R +G N
Sbjct: 593 HDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRND 652
Query: 642 ----RDRKHRRSVDR--KRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSIS-ES 694
+R+ R VDR RRD ER + + R+ + ++++ +++R + E
Sbjct: 653 ELERDERREERRVDRVDDRRDERARERDRERER-DRERERERERERDREREKERELERER 711
Query: 695 SRSGKRSSRSERDRKSDR 712
+R +R ERDR+ DR
Sbjct: 712 AREREREREKERDRERDR 729
Score = 46.6 bits (109), Expect = 8e-05
Identities = 87/479 (18%), Positives = 166/479 (34%), Gaps = 49/479 (10%)
Query: 276 EQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHN-DVEIEEA 334
+ ++++ +RQ + + ++++ E++ E+ E + ++E E ++ + + ++
Sbjct: 159 DYVHELSLEMKRQKI---QRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKS 215
Query: 335 GEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVE 394
+ +++ + S A K+ + + + ++ +S+K+ P + E +
Sbjct: 216 SKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIA 275
Query: 395 NVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDM 454
K +V + R+E + ++ E + E +P +S SP ++ S +
Sbjct: 276 LGKKYKEKYKVKD--RIEEKTRDGKDRGRDFERQREKRDKP----RSTSPAGQHHSPISS 329
Query: 455 EKESEEKEEKES----EPQPEPVAQPQPQSQPQLQ-----------LQSQSQPVLQSQPP 499
S + S P P P P Q L S S P + PP
Sbjct: 330 RHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPP 389
Query: 500 SQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTR 559
+ + +Q R+D + + + E +S S+
Sbjct: 390 RHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYE-QDQSSSRDHRD 448
Query: 560 SRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSR 619
R R++ +R S S S + SR S S+ R
Sbjct: 449 DREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYR 508
Query: 620 DSSSSTSSSSES----RSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDT 675
D + E SRS GR H R+ R + + R+ S E ++ + G SR
Sbjct: 509 DREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEI--RNDRMGRSRGR 566
Query: 676 KGS-KDKNSRSDRKRSI-SESSRSGKRSS---------------RSERDRKSDRKDKRR 717
+K SR R I S SS S S R RD+ D +RR
Sbjct: 567 VPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERR 625
Score = 40.4 bits (93), Expect = 0.006
Identities = 46/234 (19%), Positives = 97/234 (41%), Gaps = 20/234 (8%)
Query: 282 EARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKE 341
E R+ +++E +++ ++ ++ +RE E E + D E E + +
Sbjct: 1310 ERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVER 1369
Query: 342 IAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIA 401
D E + E + E K+E E E + + S+ +D M +++ V
Sbjct: 1370 DRDRDRDRTFESSQIESVKRCEAKLEGE---HERDLESTSRDSLALDKERMDKDLGSVQG 1426
Query: 402 DQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGK-ENVSALDMEKESEE 460
+E ++ R ES+E ++E+ +L+ + + +S + + + A D EK ++
Sbjct: 1427 FEETNKSERTESLEAGDDES--KLDDAHSLGSGAGEGYEPISDDELDEILAGDAEKREDQ 1484
Query: 461 KEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTP 514
++E E P+P L + L + P +P + A+L+ TP
Sbjct: 1485 QDE---EKMPDP-----------LDVIDVDWSGLMPKHPKEPREPGAALLKFTP 1524
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 83.6 bits (205), Expect = 6e-16
Identities = 102/503 (20%), Positives = 224/503 (44%), Gaps = 43/503 (8%)
Query: 107 VKKPALQSSVVATSKERTRRDLIQDQ-----------NMDEKGKQRNRRIFGLLMGTLQK 155
+KKP L+ V T+++R L+++ +++ K+R+ L T+
Sbjct: 155 IKKPWLRLGEV-TAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTITD 213
Query: 156 FKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVEL 215
+ + A ++K R +K E+Q + + + ER +L ++ Q E L ++++
Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQS 273
Query: 216 ------AQLQEE--WNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALF 267
AQ++E WN N + + + + + + +MC K+ E+ ++
Sbjct: 274 VSAKLQAQVEENELWNLLNQQQEEKM-WRQEEKIQEQEEKMCEQELKIREQEEKMWRQ-- 330
Query: 268 EGRRIEFAEQINKMEARPRRQSMKEKEHQV-VRNEEQKAEQEEGKVAQREEELEETGNQH 326
E + E E+I + E + RQ K +E + +R +E+K ++E K+ +++E+++E
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQE----- 385
Query: 327 NDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETE-VRESEKQQDSQPEE 385
+ EE +EEK E+E++ +E+ E KM E+ E +RE E++ Q E+
Sbjct: 386 ---QEEEMWRQEEK-------IREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEK 435
Query: 386 VMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPG 445
+ ++ EM+++ + + + E E ++ E + ++ E E E + ++ K L
Sbjct: 436 IRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLL--- 492
Query: 446 KENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDL 505
K+ + E++ +EEK E + + Q + + + +++ Q + Q + Q +++
Sbjct: 493 KQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEV 552
Query: 506 SLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGR 565
L L+ ++ LL T P+ V E++S + + RG
Sbjct: 553 RLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGH 612
Query: 566 ARNKTSKSRSRSSSSSSSSSSST 588
+ + + +S + S S+
Sbjct: 613 LQQYVAAYQQLASGKEALPSCSS 635
Score = 49.3 bits (116), Expect = 1e-05
Identities = 50/273 (18%), Positives = 129/273 (47%), Gaps = 31/273 (11%)
Query: 94 RESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTL 153
RE ++ +++ +++ Q + +E R + + +EK +++ R +
Sbjct: 363 REQEEKMWRQEEKIRE---QDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD 419
Query: 154 QKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKV 213
+K +++ ++++ +E+E+ ++ Q EE+ ++VE + +E E+ + ++ +++ E+K+
Sbjct: 420 EKIREQEEEMWRQEEKIRELEEMMQDQ-EEKLREVEEKMQEEEEKMQEQEEKIQRQEEKI 478
Query: 214 ELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRIE 273
Q QEE K++K +K+ E+ ++ E + E
Sbjct: 479 ---QEQEEKTWRQEKLLK-------------------QEEKIWEQEEKMWRQ--EEKMWE 514
Query: 274 FAEQINKMEARPRRQSMKEKEHQV-VRNEEQKAEQEEGKVAQREEELEETGNQHNDV--E 330
E++ + E + +RQ K +E +V + +E+K +++E ++ + EE L + G + +
Sbjct: 515 QEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGA 574
Query: 331 IEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEME 363
E+G + + + K QE + +Q+ +
Sbjct: 575 GRESGSQRLPTLTPILQVELKSQEAQSLQQQQD 607
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.301 0.119 0.305
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,736,541
Number of Sequences: 37866
Number of extensions: 1595634
Number of successful extensions: 90241
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1618
Number of HSP's successfully gapped in prelim test: 2212
Number of HSP's that attempted gapping in prelim test: 17417
Number of HSP's gapped (non-prelim): 28045
length of query: 717
length of database: 18,247,518
effective HSP length: 110
effective length of query: 607
effective length of database: 14,082,258
effective search space: 8547930606
effective search space used: 8547930606
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.