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Search of human proteins with 33285006
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33285006 Rsb-66 protein [Homo sapiens]
(168 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33285006 Rsb-66 protein [Homo sapiens] 344 2e-95
gi|221316689 cytidine triphosphate synthase II [Homo sapiens] 30 1.3
gi|28559085 cytidine triphosphate synthase II [Homo sapiens] 30 1.3
gi|28559083 cytidine triphosphate synthase II [Homo sapiens] 30 1.3
gi|4758844 nucleoporin 155kDa isoform 2 [Homo sapiens] 29 2.2
gi|24430149 nucleoporin 155kDa isoform 1 [Homo sapiens] 29 2.2
gi|116536087 phosphodiesterase 11A isoform 3 [Homo sapiens] 28 2.8
gi|116536085 phosphodiesterase 11A isoform 4 [Homo sapiens] 28 2.8
gi|197276647 leucine rich repeat (in FLII) interacting protein 2... 28 3.7
gi|8922256 estrogen-related receptor beta like 1 [Homo sapiens] 28 3.7
gi|31543535 R3H domain containing 1 [Homo sapiens] 28 4.8
gi|41349476 PR domain containing 5 [Homo sapiens] 28 4.8
gi|94400925 synaptonemal complex protein 2-like [Homo sapiens] 28 4.8
gi|221316642 nuclear distribution gene E homolog 1 [Homo sapiens] 27 6.3
gi|8923110 nuclear distribution gene E homolog 1 [Homo sapiens] 27 6.3
gi|8923224 leucine rich repeat (in FLII) interacting protein 2 i... 27 6.3
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 27 6.3
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 27 6.3
gi|4502623 cyclin H [Homo sapiens] 27 6.3
gi|155722985 SMC5 protein [Homo sapiens] 27 8.3
>gi|33285006 Rsb-66 protein [Homo sapiens]
Length = 168
Score = 344 bits (882), Expect = 2e-95
Identities = 168/168 (100%), Positives = 168/168 (100%)
Query: 1 MNEVKESLRSIEQKYKLFQQQQLTFTAALEHCRENAHDKIRPISSIGQVQSYMEHYCNSS 60
MNEVKESLRSIEQKYKLFQQQQLTFTAALEHCRENAHDKIRPISSIGQVQSYMEHYCNSS
Sbjct: 1 MNEVKESLRSIEQKYKLFQQQQLTFTAALEHCRENAHDKIRPISSIGQVQSYMEHYCNSS 60
Query: 61 TDRRVLLMFLDICSELNKLCQHFEAVHSGTPVTNNLLEKCKTLVSQSNDLSSLRAKYPHD 120
TDRRVLLMFLDICSELNKLCQHFEAVHSGTPVTNNLLEKCKTLVSQSNDLSSLRAKYPHD
Sbjct: 61 TDRRVLLMFLDICSELNKLCQHFEAVHSGTPVTNNLLEKCKTLVSQSNDLSSLRAKYPHD 120
Query: 121 VVNHLSCDEARNHYGGVVSLIPLILDLMKEWIAHSEKLPRKVLQHGTT 168
VVNHLSCDEARNHYGGVVSLIPLILDLMKEWIAHSEKLPRKVLQHGTT
Sbjct: 121 VVNHLSCDEARNHYGGVVSLIPLILDLMKEWIAHSEKLPRKVLQHGTT 168
>gi|221316689 cytidine triphosphate synthase II [Homo sapiens]
Length = 586
Score = 29.6 bits (65), Expect = 1.3
Identities = 13/40 (32%), Positives = 22/40 (55%), Gaps = 1/40 (2%)
Query: 121 VVNHLSCDEARNHY-GGVVSLIPLILDLMKEWIAHSEKLP 159
+ H+ E R Y G V ++P I D ++EW+ + K+P
Sbjct: 93 IYQHVINKERRGDYLGKTVQVVPHITDAVQEWVMNQAKVP 132
>gi|28559085 cytidine triphosphate synthase II [Homo sapiens]
Length = 586
Score = 29.6 bits (65), Expect = 1.3
Identities = 13/40 (32%), Positives = 22/40 (55%), Gaps = 1/40 (2%)
Query: 121 VVNHLSCDEARNHY-GGVVSLIPLILDLMKEWIAHSEKLP 159
+ H+ E R Y G V ++P I D ++EW+ + K+P
Sbjct: 93 IYQHVINKERRGDYLGKTVQVVPHITDAVQEWVMNQAKVP 132
>gi|28559083 cytidine triphosphate synthase II [Homo sapiens]
Length = 586
Score = 29.6 bits (65), Expect = 1.3
Identities = 13/40 (32%), Positives = 22/40 (55%), Gaps = 1/40 (2%)
Query: 121 VVNHLSCDEARNHY-GGVVSLIPLILDLMKEWIAHSEKLP 159
+ H+ E R Y G V ++P I D ++EW+ + K+P
Sbjct: 93 IYQHVINKERRGDYLGKTVQVVPHITDAVQEWVMNQAKVP 132
>gi|4758844 nucleoporin 155kDa isoform 2 [Homo sapiens]
Length = 1332
Score = 28.9 bits (63), Expect = 2.2
Identities = 33/121 (27%), Positives = 55/121 (45%), Gaps = 19/121 (15%)
Query: 3 EVKESLRSIEQKYKLFQQQQLT--FTAALEHCRENAHDKIRPISSIGQVQSYMEHYCNS- 59
E++E L+ K + + ++LT A+L +C IR +++ + +++ C
Sbjct: 754 ELQEQLKITTFKDLVIRDKELTGALIASLINCY------IRDNAAVDGISLHLQDICPLL 807
Query: 60 -STDRRVLLMFLDICSELNKLCQHFEAVHSGTPVTNNLLEKCKTLVSQSN--DLSSLRAK 116
STD ICS+ N+L Q V + T L E K SN DLS++ A+
Sbjct: 808 YSTDDA-------ICSKANELLQRSRQVQNKTEKERMLRESLKEYQKISNQVDLSNVCAQ 860
Query: 117 Y 117
Y
Sbjct: 861 Y 861
>gi|24430149 nucleoporin 155kDa isoform 1 [Homo sapiens]
Length = 1391
Score = 28.9 bits (63), Expect = 2.2
Identities = 33/121 (27%), Positives = 55/121 (45%), Gaps = 19/121 (15%)
Query: 3 EVKESLRSIEQKYKLFQQQQLT--FTAALEHCRENAHDKIRPISSIGQVQSYMEHYCNS- 59
E++E L+ K + + ++LT A+L +C IR +++ + +++ C
Sbjct: 813 ELQEQLKITTFKDLVIRDKELTGALIASLINCY------IRDNAAVDGISLHLQDICPLL 866
Query: 60 -STDRRVLLMFLDICSELNKLCQHFEAVHSGTPVTNNLLEKCKTLVSQSN--DLSSLRAK 116
STD ICS+ N+L Q V + T L E K SN DLS++ A+
Sbjct: 867 YSTDDA-------ICSKANELLQRSRQVQNKTEKERMLRESLKEYQKISNQVDLSNVCAQ 919
Query: 117 Y 117
Y
Sbjct: 920 Y 920
>gi|116536087 phosphodiesterase 11A isoform 3 [Homo sapiens]
Length = 683
Score = 28.5 bits (62), Expect = 2.8
Identities = 18/67 (26%), Positives = 25/67 (37%)
Query: 62 DRRVLLMFLDICSELNKLCQHFEAVHSGTPVTNNLLEKCKTLVSQSNDLSSLRAKYPHDV 121
D +V+ M+L C Q F A + LLE L + DL + K H
Sbjct: 105 DEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRA 164
Query: 122 VNHLSCD 128
L C+
Sbjct: 165 QTLLKCE 171
>gi|116536085 phosphodiesterase 11A isoform 4 [Homo sapiens]
Length = 933
Score = 28.5 bits (62), Expect = 2.8
Identities = 18/67 (26%), Positives = 25/67 (37%)
Query: 62 DRRVLLMFLDICSELNKLCQHFEAVHSGTPVTNNLLEKCKTLVSQSNDLSSLRAKYPHDV 121
D +V+ M+L C Q F A + LLE L + DL + K H
Sbjct: 355 DEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRA 414
Query: 122 VNHLSCD 128
L C+
Sbjct: 415 QTLLKCE 421
>gi|197276647 leucine rich repeat (in FLII) interacting protein 2
isoform 3 [Homo sapiens]
Length = 424
Score = 28.1 bits (61), Expect = 3.7
Identities = 26/102 (25%), Positives = 46/102 (45%), Gaps = 11/102 (10%)
Query: 1 MNEVKESLRSIEQKYKLFQQQQLTFTAALEHCRENAHDKIRPISSI--GQVQSYMEHYCN 58
+ E+KESL +E+KYK + + A L++ + N ++ + + Q + E Y
Sbjct: 133 LKELKESLSEVEEKYK----KAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRE 188
Query: 59 SSTDRRVLLMFLDICSELNKLCQH-FEAVHSGTPVTNNLLEK 99
+ + L +CS L QH E + G + L+EK
Sbjct: 189 NEEKSKELERQKHMCSVL----QHKMEELKEGLRQRDELIEK 226
>gi|8922256 estrogen-related receptor beta like 1 [Homo sapiens]
Length = 429
Score = 28.1 bits (61), Expect = 3.7
Identities = 23/106 (21%), Positives = 50/106 (47%), Gaps = 17/106 (16%)
Query: 76 LNKLCQHFEAVHSGTPVTNNLLEKCKTLVSQSNDLSSLRAKYPHDVVNHL---------S 126
++++ QH + S T L+K ++++ + S R KY ++ + +L
Sbjct: 265 VDQMHQHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQ 324
Query: 127 CDEARNHY----GGVVSLIPLILDLMKEWIAHSEKLPRKVLQHGTT 168
EA+ Y GGV L+ ++M+E EK+ +++ + G++
Sbjct: 325 LSEAKERYQQGNGGVTERTRLLSEVMEE----LEKVKQEMEEKGSS 366
>gi|31543535 R3H domain containing 1 [Homo sapiens]
Length = 1099
Score = 27.7 bits (60), Expect = 4.8
Identities = 16/46 (34%), Positives = 22/46 (47%), Gaps = 5/46 (10%)
Query: 30 EHCRENAHDKIRPISSIGQVQSYMEHYCNSSTDRRVLLMFLDICSE 75
EHC EN D RP+ S GQ + S+ + L+ L +C E
Sbjct: 47 EHCIENNIDLQRPLQSFGQTGKR-----SKSSSKLKLVRSLAVCEE 87
>gi|41349476 PR domain containing 5 [Homo sapiens]
Length = 630
Score = 27.7 bits (60), Expect = 4.8
Identities = 30/120 (25%), Positives = 43/120 (35%), Gaps = 17/120 (14%)
Query: 44 SSIGQVQSYMEHYCNSSTDRRVLLMFLDICSELNK----LCQHFEAVHSGTPVTNNLLEK 99
SS S+ +H D R + D C + K L +H E VH+G P +
Sbjct: 241 SSFSSASSFEQHQETCRGDARFVCK-ADSCGKRLKSKDALKRHQENVHTGDPKKKLICSV 299
Query: 100 CKTLVSQSNDLSSLRAKYPHDVVNHLSCDEARNHYGGVVSLIPLILDLMKEWIAHSEKLP 159
C S ++ L R H++ C E + L + I HSEK P
Sbjct: 300 CNKKCSSASSLQEHRK--IHEI---FDCQECMKKFISA-------NQLKRHMITHSEKRP 347
>gi|94400925 synaptonemal complex protein 2-like [Homo sapiens]
Length = 812
Score = 27.7 bits (60), Expect = 4.8
Identities = 14/39 (35%), Positives = 21/39 (53%)
Query: 12 EQKYKLFQQQQLTFTAALEHCRENAHDKIRPISSIGQVQ 50
E+K K+ Q+ LT + +L+H N DK P S + Q
Sbjct: 624 EEKPKIVNQESLTESTSLKHKLRNLEDKDIPEGSFAKSQ 662
>gi|221316642 nuclear distribution gene E homolog 1 [Homo sapiens]
Length = 335
Score = 27.3 bits (59), Expect = 6.3
Identities = 25/115 (21%), Positives = 49/115 (42%), Gaps = 13/115 (11%)
Query: 2 NEVKESLRSIEQKYKLFQQQQLTFTAALEHCRENAHDKIRPISSI-GQVQSYMEHYCNSS 60
N ++ L +I++K+++ + +ALE D + +I Q+Q Y+ ++
Sbjct: 69 NRLRMELETIKEKFEVQHSEGYRQISALE-------DDLAQTKAIKDQLQKYIRELEQAN 121
Query: 61 TD-----RRVLLMFLDICSELNKLCQHFEAVHSGTPVTNNLLEKCKTLVSQSNDL 110
D R ++ D LN+ + + S NLLE + L ++ DL
Sbjct: 122 DDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDL 176
>gi|8923110 nuclear distribution gene E homolog 1 [Homo sapiens]
Length = 335
Score = 27.3 bits (59), Expect = 6.3
Identities = 25/115 (21%), Positives = 49/115 (42%), Gaps = 13/115 (11%)
Query: 2 NEVKESLRSIEQKYKLFQQQQLTFTAALEHCRENAHDKIRPISSI-GQVQSYMEHYCNSS 60
N ++ L +I++K+++ + +ALE D + +I Q+Q Y+ ++
Sbjct: 69 NRLRMELETIKEKFEVQHSEGYRQISALE-------DDLAQTKAIKDQLQKYIRELEQAN 121
Query: 61 TD-----RRVLLMFLDICSELNKLCQHFEAVHSGTPVTNNLLEKCKTLVSQSNDL 110
D R ++ D LN+ + + S NLLE + L ++ DL
Sbjct: 122 DDLERAKRATIMSLEDFEQRLNQAIERNAFLESELDEKENLLESVQRLKDEARDL 176
>gi|8923224 leucine rich repeat (in FLII) interacting protein 2
isoform 2 [Homo sapiens]
Length = 400
Score = 27.3 bits (59), Expect = 6.3
Identities = 25/102 (24%), Positives = 47/102 (46%), Gaps = 11/102 (10%)
Query: 1 MNEVKESLRSIEQKYKLFQQQQLTFTAALEHCRENAHDKIRPISSI--GQVQSYMEHYCN 58
++E++ESL +E+KYK + + A L++ + N ++ + + Q + E Y
Sbjct: 109 LSELRESLSEVEEKYK----KAMVSNAQLDNEKNNLIYQVDTLKDVIEEQEEQMAEFYRE 164
Query: 59 SSTDRRVLLMFLDICSELNKLCQH-FEAVHSGTPVTNNLLEK 99
+ + L +CS L QH E + G + L+EK
Sbjct: 165 NEEKSKELERQKHMCSVL----QHKMEELKEGLRQRDELIEK 202
>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
[Homo sapiens]
Length = 8749
Score = 27.3 bits (59), Expect = 6.3
Identities = 29/130 (22%), Positives = 51/130 (39%), Gaps = 17/130 (13%)
Query: 5 KESLRSIEQKYKLFQQQQLTFTAALEHCRENAHDKIRPISSIGQVQSYMEHYCNSSTDRR 64
K+ + + + K F++ + L +E +K P + + + S D+R
Sbjct: 926 KKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDPEELLRRHTEFF-----SQLDQR 980
Query: 65 VLLMFLDICSELNKLCQHFEAVHSGTPVTNNLLEKCKTLVSQSNDLSSLRAKYPHDVVNH 124
VL FL C EL + E L E + L Q D L+ + P+ ++ H
Sbjct: 981 VLNAFLKACDELTDILPEQE--------QQGLQEAVRKLHKQWKD---LQGEAPYHLL-H 1028
Query: 125 LSCDEARNHY 134
L D +N +
Sbjct: 1029 LKIDVEKNRF 1038
>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
[Homo sapiens]
Length = 8797
Score = 27.3 bits (59), Expect = 6.3
Identities = 29/130 (22%), Positives = 51/130 (39%), Gaps = 17/130 (13%)
Query: 5 KESLRSIEQKYKLFQQQQLTFTAALEHCRENAHDKIRPISSIGQVQSYMEHYCNSSTDRR 64
K+ + + + K F++ + L +E +K P + + + S D+R
Sbjct: 919 KKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDPEELLRRHTEFF-----SQLDQR 973
Query: 65 VLLMFLDICSELNKLCQHFEAVHSGTPVTNNLLEKCKTLVSQSNDLSSLRAKYPHDVVNH 124
VL FL C EL + E L E + L Q D L+ + P+ ++ H
Sbjct: 974 VLNAFLKACDELTDILPEQE--------QQGLQEAVRKLHKQWKD---LQGEAPYHLL-H 1021
Query: 125 LSCDEARNHY 134
L D +N +
Sbjct: 1022 LKIDVEKNRF 1031
>gi|4502623 cyclin H [Homo sapiens]
Length = 323
Score = 27.3 bits (59), Expect = 6.3
Identities = 28/116 (24%), Positives = 42/116 (36%), Gaps = 19/116 (16%)
Query: 10 SIEQKYKLFQQQQLTFTAALEHCRENAHDKIRPISSIGQVQSYMEHYCNSST----DRRV 65
++ Y L+ Q+ TA L SS + ME Y + S +R
Sbjct: 199 ALTDAYLLYTPSQIALTAIL--------------SSASRAGITMESYLSESLMLKENRTC 244
Query: 66 LLMFLDICSELNKLCQHFEAVHS-GTPVTNNLLEKCKTLVSQSNDLSSLRAKYPHD 120
L LDI + L + +E S V LE+C + N ++ R Y D
Sbjct: 245 LSQLLDIMKSMRNLVKKYEPPRSEEVAVLKQKLERCHSAELALNVITKKRKGYEDD 300
>gi|155722985 SMC5 protein [Homo sapiens]
Length = 1101
Score = 26.9 bits (58), Expect = 8.3
Identities = 36/138 (26%), Positives = 56/138 (40%), Gaps = 28/138 (20%)
Query: 3 EVKESLRSIEQKY-------KLFQQQQLTFTAALEHCRENAHDKIRPIS----SIGQVQS 51
E K R +EQK KL +Q T LE A KI+ I+ + +
Sbjct: 699 ERKTKKRQLEQKISSKLGSLKLMEQD----TCNLEEEERKASTKIKEINVQKAKLVTELT 754
Query: 52 YMEHYCNSSTDRRV--LLMFLDICSELNKLCQHFEAVHSGTPVTNN-----------LLE 98
+ C S ++V +L + SE NKL + A S +T LL+
Sbjct: 755 NLIKICTSLHIQKVDLILQNTTVISEKNKLESDYMAASSQLRLTEQHFIELDENRQRLLQ 814
Query: 99 KCKTLVSQSNDLSSLRAK 116
KCK L+ ++ + +L A+
Sbjct: 815 KCKELMKRARQVCNLGAE 832
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.131 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,966,938
Number of Sequences: 37866
Number of extensions: 228774
Number of successful extensions: 641
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 632
Number of HSP's gapped (non-prelim): 22
length of query: 168
length of database: 18,247,518
effective HSP length: 95
effective length of query: 73
effective length of database: 14,650,248
effective search space: 1069468104
effective search space used: 1069468104
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.