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Search of human proteins with 33186882
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33186882 testis serine protease 2 [Homo sapiens]
(293 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33186882 testis serine protease 2 [Homo sapiens] 619 e-177
gi|239753543 PREDICTED: similar to hCG2041108 [Homo sapiens] 226 1e-59
gi|239748119 PREDICTED: similar to hCG2041108 [Homo sapiens] 226 1e-59
gi|239742018 PREDICTED: similar to hCG2041108 [Homo sapiens] 226 1e-59
gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens] 202 2e-52
gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ... 202 2e-52
gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ... 202 2e-52
gi|21614531 testisin isoform 2 [Homo sapiens] 180 2e-45
gi|5803197 testisin isoform 1 [Homo sapiens] 179 3e-45
gi|4506153 prostasin preproprotein [Homo sapiens] 169 3e-42
gi|148806900 epidermis-specific serine protease-like protein [Ho... 166 2e-41
gi|13994276 marapsin [Homo sapiens] 166 2e-41
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 165 4e-41
gi|21614533 testisin isoform 3 [Homo sapiens] 161 7e-40
gi|58218970 protease, serine, 36 [Homo sapiens] 159 3e-39
gi|117956391 protease, serine, 33 [Homo sapiens] 159 3e-39
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 157 8e-39
gi|205360905 testis-specific serine protease 1 [Homo sapiens] 157 1e-38
gi|148231605 ovochymase 2 [Homo sapiens] 156 2e-38
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 155 5e-38
gi|4503627 coagulation factor XI precursor [Homo sapiens] 154 7e-38
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 152 3e-37
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 152 3e-37
gi|4505881 plasminogen [Homo sapiens] 152 4e-37
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 151 6e-37
gi|68508970 tryptase beta 2 precursor [Homo sapiens] 150 1e-36
gi|32698940 transmembrane protease, serine 12 [Homo sapiens] 150 1e-36
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] 150 2e-36
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens] 149 2e-36
gi|110578663 hypothetical protein LOC203074 [Homo sapiens] 149 4e-36
>gi|33186882 testis serine protease 2 [Homo sapiens]
Length = 293
Score = 619 bits (1595), Expect = e-177
Identities = 293/293 (100%), Positives = 293/293 (100%)
Query: 1 MSSGGGSRGLLAWLLLLQPWPGQNWAGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPL 60
MSSGGGSRGLLAWLLLLQPWPGQNWAGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPL
Sbjct: 1 MSSGGGSRGLLAWLLLLQPWPGQNWAGMAAPRLPSPLLSEEGGENPEASPAPGPEAGPPL 60
Query: 61 NLFTSFPGDSLLCGRTPLRIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGH 120
NLFTSFPGDSLLCGRTPLRIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGH
Sbjct: 61 NLFTSFPGDSLLCGRTPLRIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGH 120
Query: 121 CISSRFHYSVKMGDRSVYNENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTS 180
CISSRFHYSVKMGDRSVYNENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTS
Sbjct: 121 CISSRFHYSVKMGDRSVYNENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTS 180
Query: 181 NIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKAL 240
NIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKAL
Sbjct: 181 NIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKAL 240
Query: 241 SSTKDVIIKGMVCGYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR 293
SSTKDVIIKGMVCGYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR
Sbjct: 241 SSTKDVIIKGMVCGYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR 293
>gi|239753543 PREDICTED: similar to hCG2041108 [Homo sapiens]
Length = 299
Score = 226 bits (577), Expect = 1e-59
Identities = 119/289 (41%), Positives = 173/289 (59%), Gaps = 27/289 (9%)
Query: 2 SSGGGSRGLLAWLLLLQPWPGQNWAGMAAPR------LPSPLLSEEGGENPEASP----- 50
S G S GLLAW LLLQPW + AG + PS L S GG++P AS
Sbjct: 3 SQSGSSLGLLAWFLLLQPWLEEARAGRVGAQGGVALLFPSALPSGPGGQDPGASGWEPPP 62
Query: 51 --APGPEAGPPLNLFTSFPGDSLL---CGRTPLRIVGGVDAEEGRWPWQVSVRTKGRHIC 105
APG A P P LL CG+ RI GG+ A + +WPWQVS++T RHIC
Sbjct: 63 VGAPGSPAAPQSRGNAVRPASVLLPSACGQRTSRITGGLPAPDRKWPWQVSLQTSNRHIC 122
Query: 106 GGTLVTATWVLTAGHCIS---------SRFHYSVKMGDRSVYNEN-TSVVVSVQRAFVHP 155
GG+L+ WVLTA HCIS S Y+VK+GD +V++ + T++VV V+ +H
Sbjct: 123 GGSLIARHWVLTAAHCISGVDPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVIHR 182
Query: 156 KFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLA 215
F++ I ND+AL L PVN++++IQ +C+P++ F V+ T CWVTGWGK E EK+
Sbjct: 183 YFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEKIV 242
Query: 216 SEILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVCGYKEQGKDSCQ 264
+E Q+ + I+ +++CN+++++ + +++ KG +CGY +QGKD+CQ
Sbjct: 243 TE-PQEAELSIILHDKCNEVLKEKIRMRSEMVKKGTICGYNDQGKDACQ 290
>gi|239748119 PREDICTED: similar to hCG2041108 [Homo sapiens]
Length = 299
Score = 226 bits (577), Expect = 1e-59
Identities = 119/289 (41%), Positives = 173/289 (59%), Gaps = 27/289 (9%)
Query: 2 SSGGGSRGLLAWLLLLQPWPGQNWAGMAAPR------LPSPLLSEEGGENPEASP----- 50
S G S GLLAW LLLQPW + AG + PS L S GG++P AS
Sbjct: 3 SQSGSSLGLLAWFLLLQPWLEEARAGRVGAQGGVALLFPSALPSGPGGQDPGASGWEPPP 62
Query: 51 --APGPEAGPPLNLFTSFPGDSLL---CGRTPLRIVGGVDAEEGRWPWQVSVRTKGRHIC 105
APG A P P LL CG+ RI GG+ A + +WPWQVS++T RHIC
Sbjct: 63 VGAPGSPAAPQSRGNAVRPASVLLPSACGQRTSRITGGLPAPDRKWPWQVSLQTSNRHIC 122
Query: 106 GGTLVTATWVLTAGHCIS---------SRFHYSVKMGDRSVYNEN-TSVVVSVQRAFVHP 155
GG+L+ WVLTA HCIS S Y+VK+GD +V++ + T++VV V+ +H
Sbjct: 123 GGSLIARHWVLTAAHCISGVDPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVIHR 182
Query: 156 KFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLA 215
F++ I ND+AL L PVN++++IQ +C+P++ F V+ T CWVTGWGK E EK+
Sbjct: 183 YFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEKIV 242
Query: 216 SEILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVCGYKEQGKDSCQ 264
+E Q+ + I+ +++CN+++++ + +++ KG +CGY +QGKD+CQ
Sbjct: 243 TE-PQEAELSIILHDKCNEVLKEKIRMRSEMVKKGTICGYNDQGKDACQ 290
>gi|239742018 PREDICTED: similar to hCG2041108 [Homo sapiens]
Length = 299
Score = 226 bits (577), Expect = 1e-59
Identities = 119/289 (41%), Positives = 173/289 (59%), Gaps = 27/289 (9%)
Query: 2 SSGGGSRGLLAWLLLLQPWPGQNWAGMAAPR------LPSPLLSEEGGENPEASP----- 50
S G S GLLAW LLLQPW + AG + PS L S GG++P AS
Sbjct: 3 SQSGSSLGLLAWFLLLQPWLEEARAGRVGAQGGVALLFPSALPSGPGGQDPGASGWEPPP 62
Query: 51 --APGPEAGPPLNLFTSFPGDSLL---CGRTPLRIVGGVDAEEGRWPWQVSVRTKGRHIC 105
APG A P P LL CG+ RI GG+ A + +WPWQVS++T RHIC
Sbjct: 63 VGAPGSPAAPQSRGNAVRPASVLLPSACGQRTSRITGGLPAPDRKWPWQVSLQTSNRHIC 122
Query: 106 GGTLVTATWVLTAGHCIS---------SRFHYSVKMGDRSVYNEN-TSVVVSVQRAFVHP 155
GG+L+ WVLTA HCIS S Y+VK+GD +V++ + T++VV V+ +H
Sbjct: 123 GGSLIARHWVLTAAHCISGVDPGGSSCSHLEYTVKLGDTNVHHRSKTALVVPVRDVVIHR 182
Query: 156 KFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLA 215
F++ I ND+AL L PVN++++IQ +C+P++ F V+ T CWVTGWGK E EK+
Sbjct: 183 YFTSPGIIENDIALALLDFPVNYSTHIQLVCLPEQAFMVQAGTNCWVTGWGKVNETEKIV 242
Query: 216 SEILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVCGYKEQGKDSCQ 264
+E Q+ + I+ +++CN+++++ + +++ KG +CGY +QGKD+CQ
Sbjct: 243 TE-PQEAELSIILHDKCNEVLKEKIRMRSEMVKKGTICGYNDQGKDACQ 290
>gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]
Length = 410
Score = 202 bits (515), Expect = 2e-52
Identities = 113/273 (41%), Positives = 156/273 (57%), Gaps = 32/273 (11%)
Query: 46 PEASPAPGPEA--GPPLNLFTSFP--GDSL--------------LCGRTPLRIVGGVDAE 87
PE S APG A GPP + TS G++L CG R++GG+ A
Sbjct: 111 PETSVAPGSPATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGLPAP 170
Query: 88 EGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCISSRFHYSVKMGDRSVYNENTSVVVS 147
+WPWQVS++T H CGG+L+ WVLTA HC+ F G R + + +
Sbjct: 171 NKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCV---FRGCGWEGGRWLL----AGIGR 223
Query: 148 VQRAFVH------PKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCW 201
+A+ H P T+ +D+AL L + VN++S+IQP C+P++ F+VE T CW
Sbjct: 224 WDQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECW 283
Query: 202 VTGWGKTPEREKLASE-ILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVCGYKEQGK 260
VTGWG+ E +LQ+ + IM +E+C ++++ S ++ +G VCGY +QGK
Sbjct: 284 VTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVCGYNDQGK 343
Query: 261 DSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR 293
D+CQGDSGG L CE N TWVQVGIVSWGIGCGR
Sbjct: 344 DACQGDSGGPLVCELNGTWVQVGIVSWGIGCGR 376
>gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo
sapiens]
Length = 410
Score = 202 bits (515), Expect = 2e-52
Identities = 113/273 (41%), Positives = 156/273 (57%), Gaps = 32/273 (11%)
Query: 46 PEASPAPGPEA--GPPLNLFTSFP--GDSL--------------LCGRTPLRIVGGVDAE 87
PE S APG A GPP + TS G++L CG R++GG+ A
Sbjct: 111 PETSVAPGSPATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGLPAP 170
Query: 88 EGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCISSRFHYSVKMGDRSVYNENTSVVVS 147
+WPWQVS++T H CGG+L+ WVLTA HC+ F G R + + +
Sbjct: 171 NKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCV---FRGCGWEGGRWLL----AGIGR 223
Query: 148 VQRAFVH------PKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCW 201
+A+ H P T+ +D+AL L + VN++S+IQP C+P++ F+VE T CW
Sbjct: 224 WDQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECW 283
Query: 202 VTGWGKTPEREKLASE-ILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVCGYKEQGK 260
VTGWG+ E +LQ+ + IM +E+C ++++ S ++ +G VCGY +QGK
Sbjct: 284 VTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVCGYNDQGK 343
Query: 261 DSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR 293
D+CQGDSGG L CE N TWVQVGIVSWGIGCGR
Sbjct: 344 DACQGDSGGPLVCELNGTWVQVGIVSWGIGCGR 376
>gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo
sapiens]
Length = 410
Score = 202 bits (515), Expect = 2e-52
Identities = 113/273 (41%), Positives = 156/273 (57%), Gaps = 32/273 (11%)
Query: 46 PEASPAPGPEA--GPPLNLFTSFP--GDSL--------------LCGRTPLRIVGGVDAE 87
PE S APG A GPP + TS G++L CG R++GG+ A
Sbjct: 111 PETSVAPGSPATAGPPGSWVTSASTVGEALESDGISDLGRQFSQACGHRVSRMIGGLPAP 170
Query: 88 EGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCISSRFHYSVKMGDRSVYNENTSVVVS 147
+WPWQVS++T H CGG+L+ WVLTA HC+ F G R + + +
Sbjct: 171 NKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCV---FRGCGWEGGRWLL----AGIGR 223
Query: 148 VQRAFVH------PKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCW 201
+A+ H P T+ +D+AL L + VN++S+IQP C+P++ F+VE T CW
Sbjct: 224 WDQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAGTECW 283
Query: 202 VTGWGKTPEREKLASE-ILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVCGYKEQGK 260
VTGWG+ E +LQ+ + IM +E+C ++++ S ++ +G VCGY +QGK
Sbjct: 284 VTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTVCGYNDQGK 343
Query: 261 DSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR 293
D+CQGDSGG L CE N TWVQVGIVSWGIGCGR
Sbjct: 344 DACQGDSGGPLVCELNGTWVQVGIVSWGIGCGR 376
>gi|21614531 testisin isoform 2 [Homo sapiens]
Length = 312
Score = 180 bits (456), Expect = 2e-45
Identities = 108/267 (40%), Positives = 142/267 (53%), Gaps = 26/267 (9%)
Query: 37 LLSEEGGENPEASPAPGPEAGPPLNLFTSFPGDSLLCGRTPL--RIVGGVDAEEGRWPWQ 94
LL+ G PE+ A P +GP CGR + RIVGG DAE GRWPWQ
Sbjct: 12 LLARAGLRKPESQEA-APLSGP--------------CGRRVITSRIVGGEDAELGRWPWQ 56
Query: 95 VSVRTKGRHICGGTLVTATWVLTAGHC----ISSRFHYSVKMGDRSVYNENTSVVVSVQR 150
S+R H+CG +L++ W LTA HC +S + V+ G + S+ R
Sbjct: 57 GSLRLWDSHVCGVSLLSHRWALTAAHCFETDLSDPSGWMVQFGQLTSMPSFWSLQAYYTR 116
Query: 151 AFVHPKFSTVTTIRN---DLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGK 207
FV + + + N D+AL++L PV +T +IQPIC+ F+ E RT CWVTGWG
Sbjct: 117 YFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGWGY 176
Query: 208 TPEREKLAS-EILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVCGYKEQGKDSCQGD 266
E E L S LQ+V I+ CN + K S KD+ + G + GKD+C GD
Sbjct: 177 IKEDEALPSPHTLQEVQVAIINNSMCNHLFLK-YSFRKDIFGDMVCAGNAQGGKDACFGD 235
Query: 267 SGGRLACEYNDTWVQVGIVSWGIGCGR 293
SGG LAC N W Q+G+VSWG+GCGR
Sbjct: 236 SGGPLACNKNGLWYQIGVVSWGVGCGR 262
>gi|5803197 testisin isoform 1 [Homo sapiens]
Length = 314
Score = 179 bits (454), Expect = 3e-45
Identities = 108/269 (40%), Positives = 142/269 (52%), Gaps = 28/269 (10%)
Query: 37 LLSEEGGENPEASPAPGPEAGPPLNLFTSFPGDSLLCGRTPL--RIVGGVDAEEGRWPWQ 94
LL+ G PE+ A P +GP CGR + RIVGG DAE GRWPWQ
Sbjct: 12 LLARAGLRKPESQEA-APLSGP--------------CGRRVITSRIVGGEDAELGRWPWQ 56
Query: 95 VSVRTKGRHICGGTLVTATWVLTAGHC------ISSRFHYSVKMGDRSVYNENTSVVVSV 148
S+R H+CG +L++ W LTA HC +S + V+ G + S+
Sbjct: 57 GSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYY 116
Query: 149 QRAFVHPKFSTVTTIRN---DLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGW 205
R FV + + + N D+AL++L PV +T +IQPIC+ F+ E RT CWVTGW
Sbjct: 117 TRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGW 176
Query: 206 GKTPEREKLAS-EILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVCGYKEQGKDSCQ 264
G E E L S LQ+V I+ CN + K S KD+ + G + GKD+C
Sbjct: 177 GYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLK-YSFRKDIFGDMVCAGNAQGGKDACF 235
Query: 265 GDSGGRLACEYNDTWVQVGIVSWGIGCGR 293
GDSGG LAC N W Q+G+VSWG+GCGR
Sbjct: 236 GDSGGPLACNKNGLWYQIGVVSWGVGCGR 264
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 169 bits (427), Expect = 3e-42
Identities = 95/237 (40%), Positives = 126/237 (53%), Gaps = 9/237 (3%)
Query: 64 TSFPGDSLLCGRTP-LRIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCI 122
T G CG P RI GG A G+WPWQVS+ +G H+CGG+LV+ WVL+A HC
Sbjct: 28 TGAEGAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCF 87
Query: 123 SSRFH---YSVKMGDRSVYNENTSVVVSVQRAFV-HPKFSTVTTIRNDLALLQLQHPVNF 178
S H Y VK+G + + + VS + + HP + + + D+ALLQL P+ F
Sbjct: 88 PSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGS-QGDIALLQLSRPITF 146
Query: 179 TSNIQPICIPQENFQVEGRTRCWVTGWGK-TPEREKLASEILQDVDQYIMCYEECNKIIQ 237
+ I+PIC+P N C VTGWG P L + LQ ++ ++ E CN +
Sbjct: 147 SRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYN 206
Query: 238 -KALSSTKDVIIKGMVC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCG 292
A + + MVC GY E GKD+CQGDSGG L+C W GIVSWG CG
Sbjct: 207 IDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACG 263
>gi|148806900 epidermis-specific serine protease-like protein [Homo
sapiens]
Length = 328
Score = 166 bits (421), Expect = 2e-41
Identities = 91/223 (40%), Positives = 128/223 (57%), Gaps = 11/223 (4%)
Query: 79 RIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCIS---SRFHYSVKMGDR 135
R+VGG DA GRWPWQVS+ ICGG+LV+ +LTA HCI + F Y+V +G
Sbjct: 27 RVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSERLILTAAHCIQPTWTTFSYTVWLGSI 86
Query: 136 SVYNENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVE 195
+V + V V + +HPK+ T D+ALL+L V FTS I PIC+P Q+
Sbjct: 87 TVGDSRKRVKYYVSKIVIHPKYQDTTA---DVALLKLSSQVTFTSAILPICLPSVTKQLA 143
Query: 196 GRTRCWVTGWGKTPE-REKLASEILQDVDQYIMCYEECNKI---IQKALSSTKDVIIKGM 251
CWVTGWGK E ++ LQ+ + I+ + C ++ I L + + VI +
Sbjct: 144 IPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQACEQLYNPIGIFLPALEPVIKEDK 203
Query: 252 VC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR 293
+C G + KDSC+GDSGG L+C + W+Q G+VSWG+ CG+
Sbjct: 204 ICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQTGVVSWGLECGK 246
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 166 bits (420), Expect = 2e-41
Identities = 89/230 (38%), Positives = 122/230 (53%), Gaps = 9/230 (3%)
Query: 73 CGRTPL--RIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCI---SSRFH 127
CGR + R+VGG D +EG WPWQVS++ G H CGG+L+ WVLTA HC S
Sbjct: 26 CGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSL 85
Query: 128 YSVKMGDRSVYNENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICI 187
Y V +G R + + + R T D+AL++L+ PV FT+ I P+C+
Sbjct: 86 YQVLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCL 145
Query: 188 PQENFQVEGRTRCWVTGWGKTPEREKLAS-EILQDVDQYIMCYEECNKIIQK--ALSSTK 244
P + E CWVTGWG E + L ILQ + I+ +CN + K
Sbjct: 146 PDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQP 205
Query: 245 DVIIKGMVC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR 293
I M+C G++E KD+C+GDSGG L C +W+Q G++SWG GC R
Sbjct: 206 KTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCAR 255
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 165 bits (418), Expect = 4e-41
Identities = 94/235 (40%), Positives = 133/235 (56%), Gaps = 17/235 (7%)
Query: 68 GDSLLCG-RTPLRIVGGVDAEEGRWPWQVSVRTK---GRHICGGTLVTATWVLTAGHCIS 123
GD+ +C +T RIVGG ++ G WPWQVS++ K RH+CGG+L+ WVLTA HC
Sbjct: 378 GDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD 437
Query: 124 SRFHYSVKMGDRSVYN----ENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFT 179
V + N + ++ +H + V+ +D+AL++LQ P+N+T
Sbjct: 438 GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYK-VSEGNHDIALIKLQAPLNYT 496
Query: 180 SNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKA 239
+PIC+P + T CWVTGWG + E+ ++ + ILQ V+ ++ EEC K Q
Sbjct: 497 EFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQN-ILQKVNIPLVTNEECQKRYQDY 555
Query: 240 LSSTKDVIIKGMVC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR 293
I + MVC GYKE GKD+C+GDSGG L C++N W VGI SWG GC R
Sbjct: 556 K------ITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCAR 604
>gi|21614533 testisin isoform 3 [Homo sapiens]
Length = 300
Score = 161 bits (407), Expect = 7e-40
Identities = 103/269 (38%), Positives = 134/269 (49%), Gaps = 42/269 (15%)
Query: 37 LLSEEGGENPEASPAPGPEAGPPLNLFTSFPGDSLLCGRTPL--RIVGGVDAEEGRWPWQ 94
LL+ G PE+ A P +GP CGR + RIVGG DAE GRWPWQ
Sbjct: 12 LLARAGLRKPESQEA-APLSGP--------------CGRRVITSRIVGGEDAELGRWPWQ 56
Query: 95 VSVRTKGRHICGGTLVTATWVLTAGHC------ISSRFHYSVKMGDRSVYNENTSVVVSV 148
S+R H+CG +L++ W LTA HC +S + V+ G + S+
Sbjct: 57 GSLRLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYY 116
Query: 149 QRAFVHPKFSTVTTIRN---DLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGW 205
R FV + + + N D+AL++L PV +T +IQPIC+ F+ E RT CWVTGW
Sbjct: 117 TRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTDCWVTGW 176
Query: 206 GKTPEREKLAS-EILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVCGYKEQGKDSCQ 264
G E E L S LQ+V I+ CN + K S KD+
Sbjct: 177 GYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLK-YSFRKDIF--------------GDM 221
Query: 265 GDSGGRLACEYNDTWVQVGIVSWGIGCGR 293
GDSGG LAC N W Q+G+VSWG+GCGR
Sbjct: 222 GDSGGPLACNKNGLWYQIGVVSWGVGCGR 250
>gi|58218970 protease, serine, 36 [Homo sapiens]
Length = 855
Score = 159 bits (402), Expect = 3e-39
Identities = 96/256 (37%), Positives = 130/256 (50%), Gaps = 12/256 (4%)
Query: 49 SPAPGPEAGPPLNLFTSFPGDSLLCGRTP--LRIVGGVDAEEGRWPWQVSVRTKGRHICG 106
SP PG L+ P D L CGR RIVGG +A+ G WPWQVS+ G HICG
Sbjct: 15 SPIPGAFQDSALSPTQEEPED-LDCGRPEPSARIVGGSNAQPGTWPWQVSLHHGGGHICG 73
Query: 107 GTLVTATWVLTAGHC------ISSRFHYSVKMGDRSVYNENTSVVVSVQRAFVHPKFSTV 160
G+L+ +WVL+A HC + +SV +G S A V P +
Sbjct: 74 GSLIAPSWVLSAAHCFMTNGTLEPAAEWSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQ 133
Query: 161 TTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASE-IL 219
+ DLALL+L P + + P+C+P+ + + T CW TGWG E + L +L
Sbjct: 134 VELGADLALLRLASPASLGPAVWPVCLPRASHRFVHGTACWATGWGDVQEADPLPLPWVL 193
Query: 220 QDVDQYIMCYEECNKII-QKALSSTKDVIIKGMVC-GYKEQGKDSCQGDSGGRLACEYND 277
Q+V+ ++ C + Q + I+ GM+C GY E +D+CQGDSGG L CE
Sbjct: 194 QEVELRLLGEATCQCLYSQPGPFNLTLQILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGG 253
Query: 278 TWVQVGIVSWGIGCGR 293
W Q GI S+G GCGR
Sbjct: 254 RWFQAGITSFGFGCGR 269
Score = 68.9 bits (167), Expect = 5e-12
Identities = 59/225 (26%), Positives = 84/225 (37%), Gaps = 17/225 (7%)
Query: 73 CGRTPLRIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCISSRFHYSVKM 132
CG+ P G WPW+ V G C G LV+ +WVL C
Sbjct: 325 CGKAP---------RPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPP 375
Query: 133 GDRSVYN---ENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQ 189
D + + V R H S +DLALLQL+ PVN ++ +P+C+P
Sbjct: 376 RDLDAWRVLLPSRPRAERVARLVQHENASWDNA--SDLALLQLRTPVNLSAASRPVCLPH 433
Query: 190 ENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKALSSTKDVIIK 249
+RC + WG+ L L + + + C Q A
Sbjct: 434 PEHYFLPGSRCRLARWGR--GEPALGPGALLEAELLGGWWCHCLYGRQGAAVPLPGDPPH 491
Query: 250 GMVCGYKEQGK-DSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR 293
+ Y+E+ + SC DS L C+ TW GI + GC R
Sbjct: 492 ALCPAYQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGCLR 536
Score = 63.9 bits (154), Expect = 2e-10
Identities = 50/203 (24%), Positives = 84/203 (41%), Gaps = 20/203 (9%)
Query: 91 WPWQVSVRTKGRHICGGTLVTATWVLTAGHCISSRFHYSVKMGDRSVYNENTSVVV---S 147
WPW V G +C G L+ WVL A HC+ +V + + S +
Sbjct: 601 WPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQ 660
Query: 148 VQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGK 207
V R + + +R LALL+L V + + PIC+ + CWV GW +
Sbjct: 661 VSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICLHPAG--IPPGASCWVLGWKE 718
Query: 208 TPEREKLASEILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVCG-YKEQGKDSCQGD 266
+R +A+ + I+ C+ + Q ++ G +C Y E ++ C+
Sbjct: 719 PQDRVPVAAAV------SILTQRICDCLYQ-------GILPPGTLCVLYAEGQENRCEMT 765
Query: 267 SGGRLACEYND-TWVQVGIVSWG 288
S L C+ + +W+ VG+ G
Sbjct: 766 SAPPLLCQMTEGSWILVGMAVQG 788
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 159 bits (402), Expect = 3e-39
Identities = 90/232 (38%), Positives = 127/232 (54%), Gaps = 11/232 (4%)
Query: 70 SLLCG--RTPLRIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCISSR-- 125
S CG R RIVGG D +G WPWQ S++ +G H+CGG+L+ WVLTA HC R
Sbjct: 25 SAACGQPRMSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRAL 84
Query: 126 -FHYSVKMGD-RSVYNENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQ 183
Y V++G R ++ V V+R + P +S R DLALLQL+ PV ++ +Q
Sbjct: 85 PAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSE-DGARGDLALLQLRRPVPLSARVQ 143
Query: 184 PICIPQENFQVEGRTRCWVTGWGKTPEREKLAS-EILQDVDQYIMCYEECNKI--IQKAL 240
P+C+P + T C VTGWG L LQ V ++ C+ + + +
Sbjct: 144 PVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADV 203
Query: 241 SSTKDVIIKGMVC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGC 291
+ +++ G +C GY + KD+CQGDSGG L C + +WV VG+VSWG GC
Sbjct: 204 PQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGC 255
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 157 bits (398), Expect = 8e-39
Identities = 86/225 (38%), Positives = 129/225 (57%), Gaps = 21/225 (9%)
Query: 79 RIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHC-----ISSRFHYSVKMG 133
RIVGG + EG WPWQ S++ +GRHICGG L+ WV+TA HC ++S ++V +G
Sbjct: 576 RIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFLG 635
Query: 134 DRSVYNENT---SVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQE 190
V+ + V V R +HP + + D+ALLQL HPV ++ ++P+C+P
Sbjct: 636 --KVWQNSRWPGEVSFKVSRLLLHP-YHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPAR 692
Query: 191 NFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKALSSTKDVIIKG 250
+ E CW+TGWG E + S LQ VD ++ + C+++ + ++
Sbjct: 693 SHFFEPGLHCWITGWGALREGGPI-SNALQKVDVQLIPQDLCSEVYRYQVTPR------- 744
Query: 251 MVC-GYKEQGKDSCQGDSGGRLACE-YNDTWVQVGIVSWGIGCGR 293
M+C GY++ KD+CQGDSGG L C+ + W G+VSWG+GCGR
Sbjct: 745 MLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGR 789
>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
Length = 318
Score = 157 bits (397), Expect = 1e-38
Identities = 92/252 (36%), Positives = 135/252 (53%), Gaps = 17/252 (6%)
Query: 55 EAGPPLNLFTSFPGDSLLCGRTPLR--IVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTA 112
+AGP G CG + + GGV++ GRWPWQ S+R + RH CGG+L++
Sbjct: 28 QAGPGAARRPGGGGREEACGHREIHALVAGGVESARGRWPWQASLRLRRRHRCGGSLLSR 87
Query: 113 TWVLTAGHCISSRFH---YSVKMGD----RSVYNENT-SVVVSVQRAFVHPKFSTVTTIR 164
WVL+A HC ++ ++V++G+ + +N S VQ V+P + +R
Sbjct: 88 RWVLSAAHCFQKHYYPSEWTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNP--DALGVLR 145
Query: 165 NDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGK-TPEREKLASEI-LQDV 222
ND+ALL+L V + + IQPICI F R CWVTGWG +P L L++
Sbjct: 146 NDIALLRLASSVTYNAYIQPICIESSTFNFVHRPDCWVTGWGLISPSGTPLPPPYNLREA 205
Query: 223 DQYIMCYEECNKIIQKALSSTKDVIIKGMVCGYKEQGK-DSCQGDSGGRLACEYNDTWVQ 281
I+ CN + ++ S++ +I M C E G D+C+GDSGG L C+ + W Q
Sbjct: 206 QVTILNNTRCNYLFEQ--PSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVCDKDGLWYQ 263
Query: 282 VGIVSWGIGCGR 293
VGIVSWG+ CG+
Sbjct: 264 VGIVSWGMDCGQ 275
>gi|148231605 ovochymase 2 [Homo sapiens]
Length = 564
Score = 156 bits (395), Expect = 2e-38
Identities = 82/221 (37%), Positives = 128/221 (57%), Gaps = 10/221 (4%)
Query: 79 RIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCISSRFHYS---VKMGDR 135
RI+GG E+G +PWQVS++ + +HICGG++V+ WV+TA HCI++R S V G+
Sbjct: 51 RILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEY 110
Query: 136 SV-YNENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQV 194
+ + ++++ +HP FST + D+ALL++ F + PIC+P+ Q
Sbjct: 111 DLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQF 170
Query: 195 EGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVC- 253
E C GWG+ E L S++LQ+V+ I+ +EEC + L+ + + K +C
Sbjct: 171 EAGFICTTAGWGRLTEGGVL-SQVLQEVNLPILTWEEC---VAALLTLKRPISGKTFLCT 226
Query: 254 GYKEQGKDSCQGDSGGRLAC-EYNDTWVQVGIVSWGIGCGR 293
G+ + G+D+CQGDSGG L C W G+ SWG+GCGR
Sbjct: 227 GFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGR 267
>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
Length = 321
Score = 155 bits (391), Expect = 5e-38
Identities = 94/247 (38%), Positives = 130/247 (52%), Gaps = 20/247 (8%)
Query: 56 AGPPLNLFTSFPGDSLLCGRTPL-----RIVGGVDAEEGRWPWQVSVRTKGRHICGGTLV 110
A P ++L T PG CGR + RIVGG A G WPWQ S+R + H+CGG+L+
Sbjct: 13 AVPGVSLRTLQPG----CGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLL 68
Query: 111 TATWVLTAGHCISSRFH---YSVKMGDRSVYNENTSVVVSVQRAFVHPKFSTVTTIRNDL 167
+ WVLTA HC S + Y V +G+ + + +V++ +H S D+
Sbjct: 69 SPQWVLTAAHCFSGSLNSSDYQVHLGELEI--TLSPHFSTVRQIILHSSPSGQPGTSGDI 126
Query: 168 ALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASEI-LQDVDQYI 226
AL++L PV +S I P+C+P+ + RCWVTGWG T E E L L++V +
Sbjct: 127 ALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSV 186
Query: 227 MCYEECNKIIQKALSSTKDVIIKGMVCGYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVS 286
+ E C + S ++ M+C D+CQ DSGG L C+ N WVQ GIVS
Sbjct: 187 VDTETCRRDYPGPGGS---ILQPDMLCA--RGPGDACQDDSGGPLVCQVNGAWVQAGIVS 241
Query: 287 WGIGCGR 293
WG GCGR
Sbjct: 242 WGEGCGR 248
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 154 bits (390), Expect = 7e-38
Identities = 90/224 (40%), Positives = 129/224 (57%), Gaps = 18/224 (8%)
Query: 79 RIVGGVDAEEGRWPWQVSVRTKG---RHICGGTLVTATWVLTAGHC---ISSRFHYSVKM 132
RIVGG + G WPWQV++ T RH+CGG+++ W+LTA HC + S V
Sbjct: 387 RIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYS 446
Query: 133 G--DRSVYNENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQE 190
G ++S E+TS VQ +H ++ + D+ALL+L+ VN+T + +PIC+P +
Sbjct: 447 GILNQSEIKEDTSFF-GVQEIIIHDQYKMAES-GYDIALLKLETTVNYTDSQRPICLPSK 504
Query: 191 NFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKALSSTKDVIIKG 250
+ T CWVTGWG R+K+ + LQ ++ EEC QK K I
Sbjct: 505 GDRNVIYTDCWVTGWGYRKLRDKIQNT-LQKAKIPLVTNEEC----QKRYRGHK--ITHK 557
Query: 251 MVC-GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR 293
M+C GY+E GKD+C+GDSGG L+C++N+ W VGI SWG GC +
Sbjct: 558 MICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQ 601
>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
Length = 529
Score = 152 bits (384), Expect = 3e-37
Identities = 75/220 (34%), Positives = 119/220 (54%), Gaps = 12/220 (5%)
Query: 79 RIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCI----SSRFHYSVKMGD 134
RIVGG A G WPWQVS+ + H+CGG+++T W++TA HC+ ++ +H++ G
Sbjct: 292 RIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGI 351
Query: 135 RSVYNENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQV 194
V++ HP + + T ND+AL++LQ P+ F ++P+C+P +
Sbjct: 352 LRQSFMFYGAGYQVEKVISHPNYDSKTK-NNDIALMKLQKPLTFNDLVKPVCLPNPGMML 410
Query: 195 EGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVC- 253
+ CW++GWG T E+ K SE+L ++ + CN + ++I M+C
Sbjct: 411 QPEQLCWISGWGATEEKGK-TSEVLNAAKVLLIETQRCN-----SRYVYDNLITPAMICA 464
Query: 254 GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR 293
G+ + DSCQGDSGG L N+ W +G SWG GC +
Sbjct: 465 GFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAK 504
>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
sapiens]
Length = 492
Score = 152 bits (384), Expect = 3e-37
Identities = 75/220 (34%), Positives = 119/220 (54%), Gaps = 12/220 (5%)
Query: 79 RIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCI----SSRFHYSVKMGD 134
RIVGG A G WPWQVS+ + H+CGG+++T W++TA HC+ ++ +H++ G
Sbjct: 255 RIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGI 314
Query: 135 RSVYNENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQV 194
V++ HP + + T ND+AL++LQ P+ F ++P+C+P +
Sbjct: 315 LRQSFMFYGAGYQVEKVISHPNYDSKTK-NNDIALMKLQKPLTFNDLVKPVCLPNPGMML 373
Query: 195 EGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVC- 253
+ CW++GWG T E+ K SE+L ++ + CN + ++I M+C
Sbjct: 374 QPEQLCWISGWGATEEKGK-TSEVLNAAKVLLIETQRCN-----SRYVYDNLITPAMICA 427
Query: 254 GYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR 293
G+ + DSCQGDSGG L N+ W +G SWG GC +
Sbjct: 428 GFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAK 467
>gi|4505881 plasminogen [Homo sapiens]
Length = 810
Score = 152 bits (383), Expect = 4e-37
Identities = 84/226 (37%), Positives = 120/226 (53%), Gaps = 22/226 (9%)
Query: 75 RTPLRIVGGVDAEEGRWPWQVSVRTK-GRHICGGTLVTATWVLTAGHCISSR---FHYSV 130
+ P R+VGG A WPWQVS+RT+ G H CGGTL++ WVLTA HC+ Y V
Sbjct: 576 KCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKV 635
Query: 131 KMGDRSVYNENTSVV-VSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQ 189
+G N V + V R F+ P R D+ALL+L P T + P C+P
Sbjct: 636 ILGAHQEVNLEPHVQEIEVSRLFLEPT-------RKDIALLKLSSPAVITDKVIPACLPS 688
Query: 190 ENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNK--IIQKALSSTKDVI 247
N+ V RT C++TGWG+T + + +L++ ++ + CN+ + + ST+
Sbjct: 689 PNYVVADRTECFITGWGET--QGTFGAGLLKEAQLPVIENKVCNRYEFLNGRVQSTE--- 743
Query: 248 IKGMVCGYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR 293
+ G+ G DSCQGDSGG L C D ++ G+ SWG+GC R
Sbjct: 744 ---LCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCAR 786
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 151 bits (382), Expect = 6e-37
Identities = 95/255 (37%), Positives = 129/255 (50%), Gaps = 31/255 (12%)
Query: 55 EAGPPLNLFTSFPGDSLLC---GRTPL--RIVGGVDAEEGRWPWQVSVRTKGRHICGGTL 109
EA P N TS SL C G PL RIVGG GRWPWQ SV RH CGG++
Sbjct: 188 EAWQPRNNCTSGQVVSLRCSECGARPLASRIVGGQSVAPGRWPWQASVALGFRHTCGGSV 247
Query: 110 VTATWVLTAGHCISSRFHYSVKMGDRSVYNENTSVV----------VSVQRAFVHPKFST 159
+ WV+TA HC+ +S ++ S + + +V V+R HP +S
Sbjct: 248 LAPRWVVTAAHCM-----HSFRLARLSSWRVHAGLVSHSAVRPHQGALVERIIPHPLYS- 301
Query: 160 VTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTRCWVTGWGKTPEREKLASEIL 219
D+ALL+LQ +NF+ + +C+P + +RCWV+GWG T +S++L
Sbjct: 302 AQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGSRCWVSGWGHTHPSHTYSSDML 361
Query: 220 QDVDQYIMCYEECNK--IIQKALSSTKDVIIKGMVC-GYKEQGKDSCQGDSGGRLACEYN 276
QD + + CN + AL+ M+C GY + D+CQGDSGG L C
Sbjct: 362 QDTVVPLFSTQLCNSSCVYSGALTPR-------MLCAGYLDGRADACQGDSGGPLVCPDG 414
Query: 277 DTWVQVGIVSWGIGC 291
DTW VG+VSWG GC
Sbjct: 415 DTWRLVGVVSWGRGC 429
>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
Length = 275
Score = 150 bits (380), Expect = 1e-36
Identities = 87/224 (38%), Positives = 123/224 (54%), Gaps = 14/224 (6%)
Query: 80 IVGGVDAEEGRWPWQVSVRTKGR---HICGGTLVTATWVLTAGHCISSRFH----YSVKM 132
IVGG +A +WPWQVS+R + R H CGG+L+ WVLTA HC+ V++
Sbjct: 31 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90
Query: 133 GDRSVYNENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENF 192
++ +Y ++ + VS R VHP+F T I D+ALL+L+ PVN +S++ + +P +
Sbjct: 91 REQHLYYQDQLLPVS--RIIVHPQFYTAQ-IGADIALLELEEPVNVSSHVHTVTLPPASE 147
Query: 193 QVEGRTRCWVTGWGKTPEREKLASEI-LQDVDQYIMCYEECNKIIQKALSSTKDVII--K 249
CWVTGWG E+L L+ V IM C+ + DV I
Sbjct: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207
Query: 250 GMVCGYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR 293
M+C + +DSCQGDSGG L C+ N TW+Q G+VSWG GC +
Sbjct: 208 DMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQ 250
>gi|32698940 transmembrane protease, serine 12 [Homo sapiens]
Length = 348
Score = 150 bits (379), Expect = 1e-36
Identities = 93/241 (38%), Positives = 135/241 (56%), Gaps = 28/241 (11%)
Query: 73 CGRTPL-------RIVGGVDAEEGRWPWQVSVRTK-GR---HICGGTLVTATWVLTAGHC 121
CG PL RI+GG +A+ G WPW VS++ K GR H+CGGTLV WVLTA HC
Sbjct: 64 CGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHC 123
Query: 122 ---ISSRFHYSVKMGDRSVYNENT-SVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVN 177
S ++ +G +++ + + ++ +HP F + + ND+AL L+ V
Sbjct: 124 TKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYV-NDIALFHLKKAVR 182
Query: 178 FTSNIQPICIPQENFQV-EGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKII 236
+ IQPIC+P + FQ+ +G T+C+++GWG+T E E A+ ILQD + + + E CN
Sbjct: 183 YNDYIQPICLPFDVFQILDGNTKCFISGWGRTKE-EGNATNILQDAEVHYISREMCN--- 238
Query: 237 QKALSSTKDVIIKGMVCGYKEQGK-DSCQGDSGGRLAC---EYNDTWVQVGIVSWGIGCG 292
+ S +I C E G D+C+GDSGG L C EY +V +GI S+G GCG
Sbjct: 239 --SERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFV-MGITSYGHGCG 295
Query: 293 R 293
R
Sbjct: 296 R 296
>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
Length = 275
Score = 150 bits (378), Expect = 2e-36
Identities = 87/224 (38%), Positives = 122/224 (54%), Gaps = 14/224 (6%)
Query: 80 IVGGVDAEEGRWPWQVSVRTKG---RHICGGTLVTATWVLTAGHCISSRFH----YSVKM 132
IVGG +A +WPWQVS+R G H CGG+L+ WVLTA HC+ V++
Sbjct: 31 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 90
Query: 133 GDRSVYNENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENF 192
++ +Y ++ + VS R VHP+F T I D+ALL+L+ PVN +S++ + +P +
Sbjct: 91 REQHLYYQDQLLPVS--RIIVHPQFYTAQ-IGADIALLELEEPVNVSSHVHTVTLPPASE 147
Query: 193 QVEGRTRCWVTGWGKTPEREKLASEI-LQDVDQYIMCYEECNKIIQKALSSTKDVII--K 249
CWVTGWG E+L L+ V IM C+ + DV I
Sbjct: 148 TFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRD 207
Query: 250 GMVCGYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR 293
M+C + +DSCQGDSGG L C+ N TW+Q G+VSWG GC +
Sbjct: 208 DMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQ 250
>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
Length = 2040
Score = 149 bits (377), Expect = 2e-36
Identities = 84/224 (37%), Positives = 119/224 (53%), Gaps = 27/224 (12%)
Query: 75 RTPLRIVGGVDAEEGRWPWQVSVRTK-GRHICGGTLVTATWVLTAGHCI--SSR-FHYSV 130
+ P IVGG A WPWQVS+RT+ G+H CGGTL++ WVLTA HC+ SSR Y V
Sbjct: 1815 KCPGSIVGGCVAHPHSWPWQVSLRTRFGKHFCGGTLISPEWVLTAAHCLKKSSRPSSYKV 1874
Query: 131 KMGDRSVYNENTSVV-VSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQ 189
+G N + V + V R F+ P + D+ALL+L P T + P C+P
Sbjct: 1875 ILGAHQEVNLESHVQEIEVSRLFLEPT-------QADIALLKLSRPAVITDKVMPACLPS 1927
Query: 190 ENFQVEGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKALSSTKDVIIK 249
++ V RT C++TGWG+T + + +L++ ++ E CN K
Sbjct: 1928 PDYMVTARTECYITGWGET--QGTFGTGLLKEAQLLVIENEVCNH-------------YK 1972
Query: 250 GMVCGYKEQGKDSCQGDSGGRLACEYNDTWVQVGIVSWGIGCGR 293
+ + +G DSCQGDSGG L C D ++ G+ SWG+GC R
Sbjct: 1973 YICAEHLARGTDSCQGDSGGPLVCFEKDKYILQGVTSWGLGCAR 2016
>gi|110578663 hypothetical protein LOC203074 [Homo sapiens]
Length = 352
Score = 149 bits (375), Expect = 4e-36
Identities = 97/277 (35%), Positives = 137/277 (49%), Gaps = 34/277 (12%)
Query: 31 PRLPSP------LLSEEGGENPEASPAPGPEAGPPLNLFTSFPGD-SLLCGRTPL-RIVG 82
PR P P L G P+ P P S GD S+ GRT RI G
Sbjct: 20 PRTPLPEAGVAILGRARGAHRPQPPHPPSP---------VSECGDRSIFEGRTRYSRITG 70
Query: 83 GVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCISSRFHYSVKMGDRSVYNENT 142
G++AE G +PWQVS++ + CGG+++ W+LTA HC+ S + ++ N+ T
Sbjct: 71 GMEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGTNDLT 130
Query: 143 SVVVSVQRA---FVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQVEGRTR 199
S + ++ +H F + ND+ALL L P+ PIC+P + R
Sbjct: 131 SPSMEIKEVASIILHKDFKR-ANMDNDIALLLLASPIKLDDLKVPICLPTQPGPATWR-E 188
Query: 200 CWVTGWGKTPEREKLASEI-LQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVC-GYKE 257
CWV GWG+T +K + + L IM +EEC+K+ K + K M+C GYK
Sbjct: 189 CWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPK--------LTKNMLCAGYKN 240
Query: 258 QGKDSCQGDSGGRLAC--EYNDTWVQVGIVSWGIGCG 292
+ D+C+GDSGG L C E + W QVGI+SWG CG
Sbjct: 241 ESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCG 277
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.444
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,361,944
Number of Sequences: 37866
Number of extensions: 723254
Number of successful extensions: 4338
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 186
Number of HSP's successfully gapped in prelim test: 73
Number of HSP's that attempted gapping in prelim test: 3594
Number of HSP's gapped (non-prelim): 380
length of query: 293
length of database: 18,247,518
effective HSP length: 101
effective length of query: 192
effective length of database: 14,423,052
effective search space: 2769225984
effective search space used: 2769225984
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.