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Search of human proteins with 32698866
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32698866 spindle pole body component 24 homolog [Homo
sapiens]
(197 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32698866 spindle pole body component 24 homolog [Homo sapiens] 386 e-108
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 51 6e-07
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 51 6e-07
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 51 6e-07
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 49 4e-06
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 49 4e-06
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 49 4e-06
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 49 4e-06
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 48 6e-06
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 48 6e-06
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 48 6e-06
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 48 6e-06
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 48 6e-06
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 48 6e-06
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 48 6e-06
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 48 6e-06
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 47 1e-05
gi|194353964 coiled-coil domain containing 157 [Homo sapiens] 45 4e-05
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 44 1e-04
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 43 2e-04
gi|16262452 cingulin [Homo sapiens] 43 2e-04
gi|5803145 ralA binding protein 1 [Homo sapiens] 42 3e-04
gi|31982906 cingulin-like 1 [Homo sapiens] 42 3e-04
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 42 3e-04
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 40 0.001
gi|148746195 trichohyalin [Homo sapiens] 40 0.001
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho... 40 0.001
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 40 0.001
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho... 40 0.001
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho... 40 0.001
>gi|32698866 spindle pole body component 24 homolog [Homo sapiens]
Length = 197
Score = 386 bits (991), Expect = e-108
Identities = 197/197 (100%), Positives = 197/197 (100%)
Query: 1 MAAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEK 60
MAAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEK
Sbjct: 1 MAAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEK 60
Query: 61 EVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLER 120
EVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLER
Sbjct: 61 EVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLER 120
Query: 121 QEKEVDEDTTVTIPSAVYVAQLYHQVSKIEWDYECEPGMVKGIHHGPSVAQPIHLDSTQL 180
QEKEVDEDTTVTIPSAVYVAQLYHQVSKIEWDYECEPGMVKGIHHGPSVAQPIHLDSTQL
Sbjct: 121 QEKEVDEDTTVTIPSAVYVAQLYHQVSKIEWDYECEPGMVKGIHHGPSVAQPIHLDSTQL 180
Query: 181 SRKFISDYLWSLVDTEW 197
SRKFISDYLWSLVDTEW
Sbjct: 181 SRKFISDYLWSLVDTEW 197
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 51.2 bits (121), Expect = 6e-07
Identities = 42/165 (25%), Positives = 81/165 (49%), Gaps = 9/165 (5%)
Query: 15 LSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVH 74
++ L + A+A+++ E+++ L + AEK+L+E++ +E + ++Q+
Sbjct: 1841 IAALESKLAQAEEQLEQETRERILSGKLVRR--AEKRLKEVVLQVEEERRVADQLRDQLE 1898
Query: 75 QGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDE-----DT 129
+G + ++QL+ L+EA EE +R +A +L RELE++ E + R+ +
Sbjct: 1899 KGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPL 1958
Query: 130 TVTIPSAVYVAQLYHQVSKIEWDYECEPGMVKGIHHGPSVAQPIH 174
T T + V +L V+ E E +PG G P + P H
Sbjct: 1959 TFTTRTVRQVFRLEEGVASDEEAEEAQPG--SGPSPEPEGSPPAH 2001
Score = 40.0 bits (92), Expect = 0.001
Identities = 29/110 (26%), Positives = 57/110 (51%), Gaps = 11/110 (10%)
Query: 19 GANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGV 78
G E +RRL G ++ E+++E Q AE+ ++ E+E+ +L A++ +GG
Sbjct: 1074 GRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAED---EGGA 1130
Query: 79 ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDED 128
Q L++ L+EA +A+L + +LE + E+Q +++ E+
Sbjct: 1131 RAQLLKS-LREA-------QAALAEAQEDLESERVARTKAEKQRRDLGEE 1172
Score = 38.5 bits (88), Expect = 0.004
Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 10/137 (7%)
Query: 20 ANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVE 79
A AEA +RL + E V+RL + +++L + TM+ E + L++ E+ + +
Sbjct: 1423 AREAEALTQRLAEKTE-TVDRLERGRRRLQQELDDA-TMDLEQQRQLVSTLEKKQRKFDQ 1480
Query: 80 LQQLE-AGLQEAGEEDTRLKAS-------LLQLTRELEELKEIEADLERQEKEVDEDTTV 131
L E A + A EE R +A L LTR LEE +E +LERQ + + +
Sbjct: 1481 LLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA 1540
Query: 132 TIPSAVYVAQLYHQVSK 148
+ S V + H++ +
Sbjct: 1541 LLSSKDDVGKSVHELER 1557
Score = 32.7 bits (73), Expect = 0.20
Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Query: 47 GAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQ-LT 105
G +QL E + + L A+ Q+ + Q+ EAG EAGEE R A + LT
Sbjct: 1372 GLREQLEEEAAARERAGRELQTAQAQLSEWR-RRQEEEAGALEAGEEARRRAAREAEALT 1430
Query: 106 RELEELKEIEADLERQEKEVDED 128
+ L E E LER + + ++
Sbjct: 1431 QRLAEKTETVDRLERGRRRLQQE 1453
Score = 32.0 bits (71), Expect = 0.35
Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 15/110 (13%)
Query: 27 QRRLLGRHEQVVERLLETQDGAEKQLR--EILTMEKEVAQSLLNAKEQVHQGGVELQQLE 84
+R L GR E ER + KQLR E+ E+ ++L A + +G EL++L+
Sbjct: 1602 ERDLQGRDEAGEERRRQLA----KQLRDAEVERDEERKQRTLAVAARKKLEG--ELEELK 1655
Query: 85 A-------GLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDE 127
A G +EA ++ +++A + +L RE+EE + ++ Q +E ++
Sbjct: 1656 AQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEK 1705
Score = 29.3 bits (64), Expect = 2.3
Identities = 36/159 (22%), Positives = 66/159 (41%), Gaps = 14/159 (8%)
Query: 3 AFRDIEEVSQGLLSLLGA-NRAEAQQRRLLGRHEQVV------ERLLETQDGAEKQLREI 55
A R+ E ++Q L +R E +RRL + +L+ T + +++ ++
Sbjct: 1422 AAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQL 1481
Query: 56 LTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTR----ELEEL 111
L EK + +E+ G E + L A EE+ + L + R ELE L
Sbjct: 1482 LAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1541
Query: 112 KEIEADLERQEKEVDEDTTVTIPSAVYVAQLYHQVSKIE 150
+ D+ + E++ V +A L QV+++E
Sbjct: 1542 LSSKDDVGKSVHELERACRVAEQAA---NDLRAQVTELE 1577
Score = 28.5 bits (62), Expect = 3.9
Identities = 27/128 (21%), Positives = 60/128 (46%), Gaps = 9/128 (7%)
Query: 6 DIEEVSQGLLSL-LGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQ 64
++EE+ + S G A Q R++ + +++ + ET+ E EI + +E +
Sbjct: 1650 ELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSRE----EIFSQNRESEK 1705
Query: 65 SLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASL----LQLTRELEELKEIEADLER 120
L + +V + EL + ++A ++ + + L LEE +++E L +
Sbjct: 1706 RLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQ 1765
Query: 121 QEKEVDED 128
E+E++E+
Sbjct: 1766 LEEELEEE 1773
Score = 27.7 bits (60), Expect = 6.6
Identities = 28/101 (27%), Positives = 49/101 (48%), Gaps = 7/101 (6%)
Query: 24 EAQQRRLLGRHEQVVERLLETQDGAEKQLREI--LTMEKEVAQSLLNAKEQVHQGGVELQ 81
+ Q R +G + V +L E + +QLR L E E + L A++Q + + +
Sbjct: 893 QQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELE--LVVS 950
Query: 82 QLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQE 122
+LEA GEE+ + + R + ++E+EA LE +E
Sbjct: 951 ELEA---RVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEE 988
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 51.2 bits (121), Expect = 6e-07
Identities = 42/165 (25%), Positives = 81/165 (49%), Gaps = 9/165 (5%)
Query: 15 LSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVH 74
++ L + A+A+++ E+++ L + AEK+L+E++ +E + ++Q+
Sbjct: 1833 IAALESKLAQAEEQLEQETRERILSGKLVRR--AEKRLKEVVLQVEEERRVADQLRDQLE 1890
Query: 75 QGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDE-----DT 129
+G + ++QL+ L+EA EE +R +A +L RELE++ E + R+ +
Sbjct: 1891 KGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPL 1950
Query: 130 TVTIPSAVYVAQLYHQVSKIEWDYECEPGMVKGIHHGPSVAQPIH 174
T T + V +L V+ E E +PG G P + P H
Sbjct: 1951 TFTTRTVRQVFRLEEGVASDEEAEEAQPG--SGPSPEPEGSPPAH 1993
Score = 40.0 bits (92), Expect = 0.001
Identities = 29/110 (26%), Positives = 57/110 (51%), Gaps = 11/110 (10%)
Query: 19 GANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGV 78
G E +RRL G ++ E+++E Q AE+ ++ E+E+ +L A++ +GG
Sbjct: 1066 GRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAED---EGGA 1122
Query: 79 ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDED 128
Q L++ L+EA +A+L + +LE + E+Q +++ E+
Sbjct: 1123 RAQLLKS-LREA-------QAALAEAQEDLESERVARTKAEKQRRDLGEE 1164
Score = 38.5 bits (88), Expect = 0.004
Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 10/137 (7%)
Query: 20 ANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVE 79
A AEA +RL + E V+RL + +++L + TM+ E + L++ E+ + +
Sbjct: 1415 AREAEALTQRLAEKTE-TVDRLERGRRRLQQELDDA-TMDLEQQRQLVSTLEKKQRKFDQ 1472
Query: 80 LQQLE-AGLQEAGEEDTRLKAS-------LLQLTRELEELKEIEADLERQEKEVDEDTTV 131
L E A + A EE R +A L LTR LEE +E +LERQ + + +
Sbjct: 1473 LLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA 1532
Query: 132 TIPSAVYVAQLYHQVSK 148
+ S V + H++ +
Sbjct: 1533 LLSSKDDVGKSVHELER 1549
Score = 32.7 bits (73), Expect = 0.20
Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Query: 47 GAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQ-LT 105
G +QL E + + L A+ Q+ + Q+ EAG EAGEE R A + LT
Sbjct: 1364 GLREQLEEEAAARERAGRELQTAQAQLSEWR-RRQEEEAGALEAGEEARRRAAREAEALT 1422
Query: 106 RELEELKEIEADLERQEKEVDED 128
+ L E E LER + + ++
Sbjct: 1423 QRLAEKTETVDRLERGRRRLQQE 1445
Score = 32.0 bits (71), Expect = 0.35
Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 15/110 (13%)
Query: 27 QRRLLGRHEQVVERLLETQDGAEKQLR--EILTMEKEVAQSLLNAKEQVHQGGVELQQLE 84
+R L GR E ER + KQLR E+ E+ ++L A + +G EL++L+
Sbjct: 1594 ERDLQGRDEAGEERRRQLA----KQLRDAEVERDEERKQRTLAVAARKKLEG--ELEELK 1647
Query: 85 A-------GLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDE 127
A G +EA ++ +++A + +L RE+EE + ++ Q +E ++
Sbjct: 1648 AQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEK 1697
Score = 29.3 bits (64), Expect = 2.3
Identities = 36/159 (22%), Positives = 66/159 (41%), Gaps = 14/159 (8%)
Query: 3 AFRDIEEVSQGLLSLLGA-NRAEAQQRRLLGRHEQVV------ERLLETQDGAEKQLREI 55
A R+ E ++Q L +R E +RRL + +L+ T + +++ ++
Sbjct: 1414 AAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQL 1473
Query: 56 LTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTR----ELEEL 111
L EK + +E+ G E + L A EE+ + L + R ELE L
Sbjct: 1474 LAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1533
Query: 112 KEIEADLERQEKEVDEDTTVTIPSAVYVAQLYHQVSKIE 150
+ D+ + E++ V +A L QV+++E
Sbjct: 1534 LSSKDDVGKSVHELERACRVAEQAA---NDLRAQVTELE 1569
Score = 28.5 bits (62), Expect = 3.9
Identities = 27/128 (21%), Positives = 60/128 (46%), Gaps = 9/128 (7%)
Query: 6 DIEEVSQGLLSL-LGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQ 64
++EE+ + S G A Q R++ + +++ + ET+ E EI + +E +
Sbjct: 1642 ELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSRE----EIFSQNRESEK 1697
Query: 65 SLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASL----LQLTRELEELKEIEADLER 120
L + +V + EL + ++A ++ + + L LEE +++E L +
Sbjct: 1698 RLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQ 1757
Query: 121 QEKEVDED 128
E+E++E+
Sbjct: 1758 LEEELEEE 1765
Score = 27.7 bits (60), Expect = 6.6
Identities = 28/101 (27%), Positives = 49/101 (48%), Gaps = 7/101 (6%)
Query: 24 EAQQRRLLGRHEQVVERLLETQDGAEKQLREI--LTMEKEVAQSLLNAKEQVHQGGVELQ 81
+ Q R +G + V +L E + +QLR L E E + L A++Q + + +
Sbjct: 885 QQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELE--LVVS 942
Query: 82 QLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQE 122
+LEA GEE+ + + R + ++E+EA LE +E
Sbjct: 943 ELEA---RVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEE 980
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 51.2 bits (121), Expect = 6e-07
Identities = 42/165 (25%), Positives = 81/165 (49%), Gaps = 9/165 (5%)
Query: 15 LSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVH 74
++ L + A+A+++ E+++ L + AEK+L+E++ +E + ++Q+
Sbjct: 1874 IAALESKLAQAEEQLEQETRERILSGKLVRR--AEKRLKEVVLQVEEERRVADQLRDQLE 1931
Query: 75 QGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDE-----DT 129
+G + ++QL+ L+EA EE +R +A +L RELE++ E + R+ +
Sbjct: 1932 KGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGPL 1991
Query: 130 TVTIPSAVYVAQLYHQVSKIEWDYECEPGMVKGIHHGPSVAQPIH 174
T T + V +L V+ E E +PG G P + P H
Sbjct: 1992 TFTTRTVRQVFRLEEGVASDEEAEEAQPG--SGPSPEPEGSPPAH 2034
Score = 40.0 bits (92), Expect = 0.001
Identities = 29/110 (26%), Positives = 57/110 (51%), Gaps = 11/110 (10%)
Query: 19 GANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGV 78
G E +RRL G ++ E+++E Q AE+ ++ E+E+ +L A++ +GG
Sbjct: 1107 GRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAED---EGGA 1163
Query: 79 ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDED 128
Q L++ L+EA +A+L + +LE + E+Q +++ E+
Sbjct: 1164 RAQLLKS-LREA-------QAALAEAQEDLESERVARTKAEKQRRDLGEE 1205
Score = 38.5 bits (88), Expect = 0.004
Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 10/137 (7%)
Query: 20 ANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVE 79
A AEA +RL + E V+RL + +++L + TM+ E + L++ E+ + +
Sbjct: 1456 AREAEALTQRLAEKTE-TVDRLERGRRRLQQELDDA-TMDLEQQRQLVSTLEKKQRKFDQ 1513
Query: 80 LQQLE-AGLQEAGEEDTRLKAS-------LLQLTRELEELKEIEADLERQEKEVDEDTTV 131
L E A + A EE R +A L LTR LEE +E +LERQ + + +
Sbjct: 1514 LLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEA 1573
Query: 132 TIPSAVYVAQLYHQVSK 148
+ S V + H++ +
Sbjct: 1574 LLSSKDDVGKSVHELER 1590
Score = 32.7 bits (73), Expect = 0.20
Identities = 26/83 (31%), Positives = 39/83 (46%), Gaps = 2/83 (2%)
Query: 47 GAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQ-LT 105
G +QL E + + L A+ Q+ + Q+ EAG EAGEE R A + LT
Sbjct: 1405 GLREQLEEEAAARERAGRELQTAQAQLSEWR-RRQEEEAGALEAGEEARRRAAREAEALT 1463
Query: 106 RELEELKEIEADLERQEKEVDED 128
+ L E E LER + + ++
Sbjct: 1464 QRLAEKTETVDRLERGRRRLQQE 1486
Score = 32.0 bits (71), Expect = 0.35
Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 15/110 (13%)
Query: 27 QRRLLGRHEQVVERLLETQDGAEKQLR--EILTMEKEVAQSLLNAKEQVHQGGVELQQLE 84
+R L GR E ER + KQLR E+ E+ ++L A + +G EL++L+
Sbjct: 1635 ERDLQGRDEAGEERRRQLA----KQLRDAEVERDEERKQRTLAVAARKKLEG--ELEELK 1688
Query: 85 A-------GLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDE 127
A G +EA ++ +++A + +L RE+EE + ++ Q +E ++
Sbjct: 1689 AQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEK 1738
Score = 29.3 bits (64), Expect = 2.3
Identities = 36/159 (22%), Positives = 66/159 (41%), Gaps = 14/159 (8%)
Query: 3 AFRDIEEVSQGLLSLLGA-NRAEAQQRRLLGRHEQVV------ERLLETQDGAEKQLREI 55
A R+ E ++Q L +R E +RRL + +L+ T + +++ ++
Sbjct: 1455 AAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQL 1514
Query: 56 LTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTR----ELEEL 111
L EK + +E+ G E + L A EE+ + L + R ELE L
Sbjct: 1515 LAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1574
Query: 112 KEIEADLERQEKEVDEDTTVTIPSAVYVAQLYHQVSKIE 150
+ D+ + E++ V +A L QV+++E
Sbjct: 1575 LSSKDDVGKSVHELERACRVAEQAA---NDLRAQVTELE 1610
Score = 28.5 bits (62), Expect = 3.9
Identities = 27/128 (21%), Positives = 60/128 (46%), Gaps = 9/128 (7%)
Query: 6 DIEEVSQGLLSL-LGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQ 64
++EE+ + S G A Q R++ + +++ + ET+ E EI + +E +
Sbjct: 1683 ELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSRE----EIFSQNRESEK 1738
Query: 65 SLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASL----LQLTRELEELKEIEADLER 120
L + +V + EL + ++A ++ + + L LEE +++E L +
Sbjct: 1739 RLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQ 1798
Query: 121 QEKEVDED 128
E+E++E+
Sbjct: 1799 LEEELEEE 1806
Score = 27.7 bits (60), Expect = 6.6
Identities = 28/101 (27%), Positives = 49/101 (48%), Gaps = 7/101 (6%)
Query: 24 EAQQRRLLGRHEQVVERLLETQDGAEKQLREI--LTMEKEVAQSLLNAKEQVHQGGVELQ 81
+ Q R +G + V +L E + +QLR L E E + L A++Q + + +
Sbjct: 926 QQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELE--LVVS 983
Query: 82 QLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQE 122
+LEA GEE+ + + R + ++E+EA LE +E
Sbjct: 984 ELEA---RVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEE 1021
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 48.5 bits (114), Expect = 4e-06
Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 3/89 (3%)
Query: 33 RHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGE 92
R +Q + L+ +D K+L+EIL ++ + KEQ +G ++QL+ L+EA E
Sbjct: 1835 REKQAATKSLKQKD---KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEE 1891
Query: 93 EDTRLKASLLQLTRELEELKEIEADLERQ 121
E R+ A+ +L REL+E E + R+
Sbjct: 1892 ESQRINANRRKLQRELDEATESNEAMGRE 1920
Score = 38.9 bits (89), Expect = 0.003
Identities = 35/131 (26%), Positives = 65/131 (49%), Gaps = 17/131 (12%)
Query: 8 EEVSQGLLSLL-GANRAEAQQRRLLGRHEQVVERLLETQDGAE-------------KQLR 53
EE+++ L S L G N + ++RRL R Q+ E L E Q E +QL
Sbjct: 1711 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLS 1770
Query: 54 EILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKE 113
L E+ AQ +A++Q+ + EL+ ++ G ++ K+++ L ++ +L+E
Sbjct: 1771 NELATERSTAQKNESARQQLERQNKELRSKLHEME--GAVKSKFKSTIAALEAKIAQLEE 1828
Query: 114 IEADLERQEKE 124
+ + E +EK+
Sbjct: 1829 -QVEQEAREKQ 1838
Score = 36.2 bits (82), Expect = 0.019
Identities = 31/120 (25%), Positives = 58/120 (48%), Gaps = 11/120 (9%)
Query: 24 EAQQRR---LLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSL---LNAKEQVHQGG 77
E +QR+ LL + + + + +D AE + RE T +A++L L AKE++ +
Sbjct: 1447 EKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN 1506
Query: 78 ----VELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTTVTI 133
E++ L + + G+ L+ S L ++EE+K +LE E + ED + +
Sbjct: 1507 KMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE-DELQATEDAKLRL 1565
Score = 34.7 bits (78), Expect = 0.054
Identities = 25/123 (20%), Positives = 59/123 (47%), Gaps = 9/123 (7%)
Query: 15 LSLLGANRAEAQQR-----RLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNA 69
+S L N AE +++ +L +HE ++ L EK +E+ +++++ +
Sbjct: 1008 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1067
Query: 70 KEQVHQGGVELQQLEAGLQEAGEE----DTRLKASLLQLTRELEELKEIEADLERQEKEV 125
EQ+ ++ +L+ L + EE RL + Q L++++E+E + ++++
Sbjct: 1068 HEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDL 1127
Query: 126 DED 128
D +
Sbjct: 1128 DSE 1130
Score = 34.3 bits (77), Expect = 0.070
Identities = 27/110 (24%), Positives = 56/110 (50%), Gaps = 14/110 (12%)
Query: 21 NRAEAQQRRLLGRHEQVVERLLETQD--GAEKQLREILTMEKEVAQSLLNAKEQVHQGGV 78
N+AE Q+R L E + L +T D +++LR E V + L+ + + H+
Sbjct: 1135 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHE--A 1192
Query: 79 ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDED 128
++Q++ +A EE LT +LE+ K +A+L++ ++ ++++
Sbjct: 1193 QVQEMRQKHAQAVEE----------LTEQLEQFKRAKANLDKNKQTLEKE 1232
Score = 32.7 bits (73), Expect = 0.20
Identities = 27/104 (25%), Positives = 49/104 (47%), Gaps = 3/104 (2%)
Query: 22 RAEAQQRRLLGRHEQVVER--LLETQDGAEKQL-REILTMEKEVAQSLLNAKEQVHQGGV 78
+AE + + L +H Q+ E LL+ Q AE +L E M +A +E +H+
Sbjct: 870 KAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEA 929
Query: 79 ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQE 122
L++ E Q+ E ++ +L L +LEE + L+ ++
Sbjct: 930 RLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEK 973
Score = 32.0 bits (71), Expect = 0.35
Identities = 35/145 (24%), Positives = 65/145 (44%), Gaps = 12/145 (8%)
Query: 5 RDIEEVSQGLLSLLGA-NRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVA 63
++IE ++Q A ++ E + RL +Q ++ L+ D + + + +++
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRL----QQELDDLVVDLDNQRQLVSNLEKKQRKFD 1454
Query: 64 QSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEK 123
Q L K + E + EA EA E++T+ L L R LEE E + +LER K
Sbjct: 1455 QLLAEEKNISSKYADERDRAEA---EAREKETKA----LSLARALEEALEAKEELERTNK 1507
Query: 124 EVDEDTTVTIPSAVYVAQLYHQVSK 148
+ + + S V + H++ K
Sbjct: 1508 MLKAEMEDLVSSKDDVGKNVHELEK 1532
Score = 29.3 bits (64), Expect = 2.3
Identities = 34/134 (25%), Positives = 66/134 (49%), Gaps = 16/134 (11%)
Query: 7 IEEVSQGLLSLLGAN-RAEAQQRRLLGRHEQVVERLLETQDGAEKQL-REILTMEKEVA- 63
+EE+ L + A R E + L G+ E+ ++ E + +QL R++ E E+
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELED 1607
Query: 64 ----QSLLNAKEQVHQGGVELQQLEA-----GLQEAGEEDTRLKASLLQLTRELEELK-- 112
++L A ++ +G ++ +L+A G +EA ++ +L+A + RELE+ +
Sbjct: 1608 ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARAS 1667
Query: 113 --EIEADLERQEKE 124
EI A + EK+
Sbjct: 1668 RDEIFATAKENEKK 1681
Score = 28.9 bits (63), Expect = 3.0
Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Query: 50 KQLREILTMEKEVA---QSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTR 106
K L ++ E+E+ L KE+ + EL++LE + EE L+ L T
Sbjct: 842 KPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETE 901
Query: 107 ELEELKEIEADLERQEKEVDE 127
E +E+ L +++E++E
Sbjct: 902 LYAEAEEMRVRLAAKKQELEE 922
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 48.5 bits (114), Expect = 4e-06
Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 3/89 (3%)
Query: 33 RHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGE 92
R +Q + L+ +D K+L+EIL ++ + KEQ +G ++QL+ L+EA E
Sbjct: 1842 REKQAATKSLKQKD---KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEE 1898
Query: 93 EDTRLKASLLQLTRELEELKEIEADLERQ 121
E R+ A+ +L REL+E E + R+
Sbjct: 1899 ESQRINANRRKLQRELDEATESNEAMGRE 1927
Score = 38.9 bits (89), Expect = 0.003
Identities = 35/131 (26%), Positives = 65/131 (49%), Gaps = 17/131 (12%)
Query: 8 EEVSQGLLSLL-GANRAEAQQRRLLGRHEQVVERLLETQDGAE-------------KQLR 53
EE+++ L S L G N + ++RRL R Q+ E L E Q E +QL
Sbjct: 1718 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLS 1777
Query: 54 EILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKE 113
L E+ AQ +A++Q+ + EL+ ++ G ++ K+++ L ++ +L+E
Sbjct: 1778 NELATERSTAQKNESARQQLERQNKELRSKLHEME--GAVKSKFKSTIAALEAKIAQLEE 1835
Query: 114 IEADLERQEKE 124
+ + E +EK+
Sbjct: 1836 -QVEQEAREKQ 1845
Score = 36.2 bits (82), Expect = 0.019
Identities = 31/120 (25%), Positives = 58/120 (48%), Gaps = 11/120 (9%)
Query: 24 EAQQRR---LLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSL---LNAKEQVHQGG 77
E +QR+ LL + + + + +D AE + RE T +A++L L AKE++ +
Sbjct: 1454 EKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN 1513
Query: 78 ----VELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTTVTI 133
E++ L + + G+ L+ S L ++EE+K +LE E + ED + +
Sbjct: 1514 KMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE-DELQATEDAKLRL 1572
Score = 34.7 bits (78), Expect = 0.054
Identities = 25/123 (20%), Positives = 59/123 (47%), Gaps = 9/123 (7%)
Query: 15 LSLLGANRAEAQQR-----RLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNA 69
+S L N AE +++ +L +HE ++ L EK +E+ +++++ +
Sbjct: 1015 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1074
Query: 70 KEQVHQGGVELQQLEAGLQEAGEE----DTRLKASLLQLTRELEELKEIEADLERQEKEV 125
EQ+ ++ +L+ L + EE RL + Q L++++E+E + ++++
Sbjct: 1075 HEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDL 1134
Query: 126 DED 128
D +
Sbjct: 1135 DSE 1137
Score = 34.3 bits (77), Expect = 0.070
Identities = 27/110 (24%), Positives = 56/110 (50%), Gaps = 14/110 (12%)
Query: 21 NRAEAQQRRLLGRHEQVVERLLETQD--GAEKQLREILTMEKEVAQSLLNAKEQVHQGGV 78
N+AE Q+R L E + L +T D +++LR E V + L+ + + H+
Sbjct: 1142 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHE--A 1199
Query: 79 ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDED 128
++Q++ +A EE LT +LE+ K +A+L++ ++ ++++
Sbjct: 1200 QVQEMRQKHAQAVEE----------LTEQLEQFKRAKANLDKNKQTLEKE 1239
Score = 32.7 bits (73), Expect = 0.20
Identities = 27/104 (25%), Positives = 49/104 (47%), Gaps = 3/104 (2%)
Query: 22 RAEAQQRRLLGRHEQVVER--LLETQDGAEKQL-REILTMEKEVAQSLLNAKEQVHQGGV 78
+AE + + L +H Q+ E LL+ Q AE +L E M +A +E +H+
Sbjct: 877 KAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEA 936
Query: 79 ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQE 122
L++ E Q+ E ++ +L L +LEE + L+ ++
Sbjct: 937 RLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEK 980
Score = 32.0 bits (71), Expect = 0.35
Identities = 35/145 (24%), Positives = 65/145 (44%), Gaps = 12/145 (8%)
Query: 5 RDIEEVSQGLLSLLGA-NRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVA 63
++IE ++Q A ++ E + RL +Q ++ L+ D + + + +++
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRL----QQELDDLVVDLDNQRQLVSNLEKKQRKFD 1461
Query: 64 QSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEK 123
Q L K + E + EA EA E++T+ L L R LEE E + +LER K
Sbjct: 1462 QLLAEEKNISSKYADERDRAEA---EAREKETKA----LSLARALEEALEAKEELERTNK 1514
Query: 124 EVDEDTTVTIPSAVYVAQLYHQVSK 148
+ + + S V + H++ K
Sbjct: 1515 MLKAEMEDLVSSKDDVGKNVHELEK 1539
Score = 29.3 bits (64), Expect = 2.3
Identities = 34/134 (25%), Positives = 66/134 (49%), Gaps = 16/134 (11%)
Query: 7 IEEVSQGLLSLLGAN-RAEAQQRRLLGRHEQVVERLLETQDGAEKQL-REILTMEKEVA- 63
+EE+ L + A R E + L G+ E+ ++ E + +QL R++ E E+
Sbjct: 1555 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELED 1614
Query: 64 ----QSLLNAKEQVHQGGVELQQLEA-----GLQEAGEEDTRLKASLLQLTRELEELK-- 112
++L A ++ +G ++ +L+A G +EA ++ +L+A + RELE+ +
Sbjct: 1615 ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARAS 1674
Query: 113 --EIEADLERQEKE 124
EI A + EK+
Sbjct: 1675 RDEIFATAKENEKK 1688
Score = 28.9 bits (63), Expect = 3.0
Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Query: 50 KQLREILTMEKEVA---QSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTR 106
K L ++ E+E+ L KE+ + EL++LE + EE L+ L T
Sbjct: 849 KPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETE 908
Query: 107 ELEELKEIEADLERQEKEVDE 127
E +E+ L +++E++E
Sbjct: 909 LYAEAEEMRVRLAAKKQELEE 929
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 48.5 bits (114), Expect = 4e-06
Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 3/89 (3%)
Query: 33 RHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGE 92
R +Q + L+ +D K+L+EIL ++ + KEQ +G ++QL+ L+EA E
Sbjct: 1842 REKQAATKSLKQKD---KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEE 1898
Query: 93 EDTRLKASLLQLTRELEELKEIEADLERQ 121
E R+ A+ +L REL+E E + R+
Sbjct: 1899 ESQRINANRRKLQRELDEATESNEAMGRE 1927
Score = 38.9 bits (89), Expect = 0.003
Identities = 35/131 (26%), Positives = 65/131 (49%), Gaps = 17/131 (12%)
Query: 8 EEVSQGLLSLL-GANRAEAQQRRLLGRHEQVVERLLETQDGAE-------------KQLR 53
EE+++ L S L G N + ++RRL R Q+ E L E Q E +QL
Sbjct: 1718 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLS 1777
Query: 54 EILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKE 113
L E+ AQ +A++Q+ + EL+ ++ G ++ K+++ L ++ +L+E
Sbjct: 1778 NELATERSTAQKNESARQQLERQNKELRSKLHEME--GAVKSKFKSTIAALEAKIAQLEE 1835
Query: 114 IEADLERQEKE 124
+ + E +EK+
Sbjct: 1836 -QVEQEAREKQ 1845
Score = 36.2 bits (82), Expect = 0.019
Identities = 31/120 (25%), Positives = 58/120 (48%), Gaps = 11/120 (9%)
Query: 24 EAQQRR---LLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSL---LNAKEQVHQGG 77
E +QR+ LL + + + + +D AE + RE T +A++L L AKE++ +
Sbjct: 1454 EKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN 1513
Query: 78 ----VELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTTVTI 133
E++ L + + G+ L+ S L ++EE+K +LE E + ED + +
Sbjct: 1514 KMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE-DELQATEDAKLRL 1572
Score = 34.7 bits (78), Expect = 0.054
Identities = 25/123 (20%), Positives = 59/123 (47%), Gaps = 9/123 (7%)
Query: 15 LSLLGANRAEAQQR-----RLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNA 69
+S L N AE +++ +L +HE ++ L EK +E+ +++++ +
Sbjct: 1015 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1074
Query: 70 KEQVHQGGVELQQLEAGLQEAGEE----DTRLKASLLQLTRELEELKEIEADLERQEKEV 125
EQ+ ++ +L+ L + EE RL + Q L++++E+E + ++++
Sbjct: 1075 HEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDL 1134
Query: 126 DED 128
D +
Sbjct: 1135 DSE 1137
Score = 34.3 bits (77), Expect = 0.070
Identities = 27/110 (24%), Positives = 56/110 (50%), Gaps = 14/110 (12%)
Query: 21 NRAEAQQRRLLGRHEQVVERLLETQD--GAEKQLREILTMEKEVAQSLLNAKEQVHQGGV 78
N+AE Q+R L E + L +T D +++LR E V + L+ + + H+
Sbjct: 1142 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHE--A 1199
Query: 79 ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDED 128
++Q++ +A EE LT +LE+ K +A+L++ ++ ++++
Sbjct: 1200 QVQEMRQKHAQAVEE----------LTEQLEQFKRAKANLDKNKQTLEKE 1239
Score = 32.7 bits (73), Expect = 0.20
Identities = 27/104 (25%), Positives = 49/104 (47%), Gaps = 3/104 (2%)
Query: 22 RAEAQQRRLLGRHEQVVER--LLETQDGAEKQL-REILTMEKEVAQSLLNAKEQVHQGGV 78
+AE + + L +H Q+ E LL+ Q AE +L E M +A +E +H+
Sbjct: 877 KAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEA 936
Query: 79 ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQE 122
L++ E Q+ E ++ +L L +LEE + L+ ++
Sbjct: 937 RLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEK 980
Score = 32.0 bits (71), Expect = 0.35
Identities = 35/145 (24%), Positives = 65/145 (44%), Gaps = 12/145 (8%)
Query: 5 RDIEEVSQGLLSLLGA-NRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVA 63
++IE ++Q A ++ E + RL +Q ++ L+ D + + + +++
Sbjct: 1406 KEIENLTQQYEEKAAAYDKLEKTKNRL----QQELDDLVVDLDNQRQLVSNLEKKQRKFD 1461
Query: 64 QSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEK 123
Q L K + E + EA EA E++T+ L L R LEE E + +LER K
Sbjct: 1462 QLLAEEKNISSKYADERDRAEA---EAREKETKA----LSLARALEEALEAKEELERTNK 1514
Query: 124 EVDEDTTVTIPSAVYVAQLYHQVSK 148
+ + + S V + H++ K
Sbjct: 1515 MLKAEMEDLVSSKDDVGKNVHELEK 1539
Score = 29.3 bits (64), Expect = 2.3
Identities = 34/134 (25%), Positives = 66/134 (49%), Gaps = 16/134 (11%)
Query: 7 IEEVSQGLLSLLGAN-RAEAQQRRLLGRHEQVVERLLETQDGAEKQL-REILTMEKEVA- 63
+EE+ L + A R E + L G+ E+ ++ E + +QL R++ E E+
Sbjct: 1555 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELED 1614
Query: 64 ----QSLLNAKEQVHQGGVELQQLEA-----GLQEAGEEDTRLKASLLQLTRELEELK-- 112
++L A ++ +G ++ +L+A G +EA ++ +L+A + RELE+ +
Sbjct: 1615 ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARAS 1674
Query: 113 --EIEADLERQEKE 124
EI A + EK+
Sbjct: 1675 RDEIFATAKENEKK 1688
Score = 28.9 bits (63), Expect = 3.0
Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Query: 50 KQLREILTMEKEVA---QSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTR 106
K L ++ E+E+ L KE+ + EL++LE + EE L+ L T
Sbjct: 849 KPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETE 908
Query: 107 ELEELKEIEADLERQEKEVDE 127
E +E+ L +++E++E
Sbjct: 909 LYAEAEEMRVRLAAKKQELEE 929
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 48.5 bits (114), Expect = 4e-06
Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 3/89 (3%)
Query: 33 RHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGE 92
R +Q + L+ +D K+L+EIL ++ + KEQ +G ++QL+ L+EA E
Sbjct: 1835 REKQAATKSLKQKD---KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEE 1891
Query: 93 EDTRLKASLLQLTRELEELKEIEADLERQ 121
E R+ A+ +L REL+E E + R+
Sbjct: 1892 ESQRINANRRKLQRELDEATESNEAMGRE 1920
Score = 38.9 bits (89), Expect = 0.003
Identities = 35/131 (26%), Positives = 65/131 (49%), Gaps = 17/131 (12%)
Query: 8 EEVSQGLLSLL-GANRAEAQQRRLLGRHEQVVERLLETQDGAE-------------KQLR 53
EE+++ L S L G N + ++RRL R Q+ E L E Q E +QL
Sbjct: 1711 EELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLS 1770
Query: 54 EILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKE 113
L E+ AQ +A++Q+ + EL+ ++ G ++ K+++ L ++ +L+E
Sbjct: 1771 NELATERSTAQKNESARQQLERQNKELRSKLHEME--GAVKSKFKSTIAALEAKIAQLEE 1828
Query: 114 IEADLERQEKE 124
+ + E +EK+
Sbjct: 1829 -QVEQEAREKQ 1838
Score = 36.2 bits (82), Expect = 0.019
Identities = 31/120 (25%), Positives = 58/120 (48%), Gaps = 11/120 (9%)
Query: 24 EAQQRR---LLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSL---LNAKEQVHQGG 77
E +QR+ LL + + + + +D AE + RE T +A++L L AKE++ +
Sbjct: 1447 EKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTN 1506
Query: 78 ----VELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTTVTI 133
E++ L + + G+ L+ S L ++EE+K +LE E + ED + +
Sbjct: 1507 KMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELE-DELQATEDAKLRL 1565
Score = 34.7 bits (78), Expect = 0.054
Identities = 25/123 (20%), Positives = 59/123 (47%), Gaps = 9/123 (7%)
Query: 15 LSLLGANRAEAQQR-----RLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNA 69
+S L N AE +++ +L +HE ++ L EK +E+ +++++ +
Sbjct: 1008 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1067
Query: 70 KEQVHQGGVELQQLEAGLQEAGEE----DTRLKASLLQLTRELEELKEIEADLERQEKEV 125
EQ+ ++ +L+ L + EE RL + Q L++++E+E + ++++
Sbjct: 1068 HEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDL 1127
Query: 126 DED 128
D +
Sbjct: 1128 DSE 1130
Score = 34.3 bits (77), Expect = 0.070
Identities = 27/110 (24%), Positives = 56/110 (50%), Gaps = 14/110 (12%)
Query: 21 NRAEAQQRRLLGRHEQVVERLLETQD--GAEKQLREILTMEKEVAQSLLNAKEQVHQGGV 78
N+AE Q+R L E + L +T D +++LR E V + L+ + + H+
Sbjct: 1135 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHE--A 1192
Query: 79 ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDED 128
++Q++ +A EE LT +LE+ K +A+L++ ++ ++++
Sbjct: 1193 QVQEMRQKHAQAVEE----------LTEQLEQFKRAKANLDKNKQTLEKE 1232
Score = 32.7 bits (73), Expect = 0.20
Identities = 27/104 (25%), Positives = 49/104 (47%), Gaps = 3/104 (2%)
Query: 22 RAEAQQRRLLGRHEQVVER--LLETQDGAEKQL-REILTMEKEVAQSLLNAKEQVHQGGV 78
+AE + + L +H Q+ E LL+ Q AE +L E M +A +E +H+
Sbjct: 870 KAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEA 929
Query: 79 ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQE 122
L++ E Q+ E ++ +L L +LEE + L+ ++
Sbjct: 930 RLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEK 973
Score = 32.0 bits (71), Expect = 0.35
Identities = 35/145 (24%), Positives = 65/145 (44%), Gaps = 12/145 (8%)
Query: 5 RDIEEVSQGLLSLLGA-NRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVA 63
++IE ++Q A ++ E + RL +Q ++ L+ D + + + +++
Sbjct: 1399 KEIENLTQQYEEKAAAYDKLEKTKNRL----QQELDDLVVDLDNQRQLVSNLEKKQRKFD 1454
Query: 64 QSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEK 123
Q L K + E + EA EA E++T+ L L R LEE E + +LER K
Sbjct: 1455 QLLAEEKNISSKYADERDRAEA---EAREKETKA----LSLARALEEALEAKEELERTNK 1507
Query: 124 EVDEDTTVTIPSAVYVAQLYHQVSK 148
+ + + S V + H++ K
Sbjct: 1508 MLKAEMEDLVSSKDDVGKNVHELEK 1532
Score = 29.3 bits (64), Expect = 2.3
Identities = 34/134 (25%), Positives = 66/134 (49%), Gaps = 16/134 (11%)
Query: 7 IEEVSQGLLSLLGAN-RAEAQQRRLLGRHEQVVERLLETQDGAEKQL-REILTMEKEVA- 63
+EE+ L + A R E + L G+ E+ ++ E + +QL R++ E E+
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELED 1607
Query: 64 ----QSLLNAKEQVHQGGVELQQLEA-----GLQEAGEEDTRLKASLLQLTRELEELK-- 112
++L A ++ +G ++ +L+A G +EA ++ +L+A + RELE+ +
Sbjct: 1608 ERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARAS 1667
Query: 113 --EIEADLERQEKE 124
EI A + EK+
Sbjct: 1668 RDEIFATAKENEKK 1681
Score = 28.9 bits (63), Expect = 3.0
Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 3/81 (3%)
Query: 50 KQLREILTMEKEVA---QSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTR 106
K L ++ E+E+ L KE+ + EL++LE + EE L+ L T
Sbjct: 842 KPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETE 901
Query: 107 ELEELKEIEADLERQEKEVDE 127
E +E+ L +++E++E
Sbjct: 902 LYAEAEEMRVRLAAKKQELEE 922
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 47.8 bits (112), Expect = 6e-06
Identities = 35/118 (29%), Positives = 65/118 (55%), Gaps = 9/118 (7%)
Query: 20 ANRAEAQQRRLLGRHEQVVERLLETQDG-AEKQLREILTMEKEVAQSLLNAKEQVHQGGV 78
A RA+A+Q L R +Q + +E AE+ LR+ +E+E+ L +E HQ +
Sbjct: 2147 ARRAQAEQAAL--RQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNL 2204
Query: 79 ---ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEV---DEDTT 130
ELQ+L+A EA + ++++ L + ++EEL +++A +E + + + D+D T
Sbjct: 2205 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2262
Score = 40.4 bits (93), Expect = 0.001
Identities = 33/116 (28%), Positives = 60/116 (51%), Gaps = 8/116 (6%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLRE----ILTMEKEVAQSLLNAKEQVHQGG 77
R EA+ R L+ R + +R L+ + KQ+ E + +E A+ A+E + Q
Sbjct: 2246 RIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQR 2305
Query: 78 VELQQLEAGLQEAGEEDTRLK--ASLLQLTREL--EELKEIEADLERQEKEVDEDT 129
+++ +A +E TRLK A LLQ +EL E+ + ++ D E+ +++ E+T
Sbjct: 2306 ALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2361
Score = 35.4 bits (80), Expect = 0.032
Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 12/125 (9%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQ 81
R E ++R + + ERL E + EKQ +++A++ AK Q + ELQ
Sbjct: 1343 RMEEEERLAEQQRAEERERLAEVEAALEKQ--------RQLAEAHAQAKAQAEREAKELQ 1394
Query: 82 QL----EAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTTVTIPSAV 137
Q +EA + + K S+ + ++L + E E + ++ E E + + I +
Sbjct: 1395 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1454
Query: 138 YVAQL 142
V +L
Sbjct: 1455 RVVRL 1459
Score = 33.9 bits (76), Expect = 0.092
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 21/127 (16%)
Query: 23 AEAQQRRLLGRHEQVVERLLETQDG------AEKQLREILTMEKE--------VAQSLLN 68
A+ Q RRL EQ+ ++L E G AE+Q + ++ E E ++++
Sbjct: 2339 AQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQAR 2398
Query: 69 AKE-------QVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQ 121
A+E Q + G +L + E QE L+ Q + E L+E A+LER+
Sbjct: 2399 AEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELERE 2458
Query: 122 EKEVDED 128
++++ ++
Sbjct: 2459 KEKLQQE 2465
Score = 33.1 bits (74), Expect = 0.16
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 9/105 (8%)
Query: 26 QQRRLLGRHEQVVERLLE-TQDGAEKQLRE--------ILTMEKEVAQSLLNAKEQVHQG 76
+ RRL R EQ R L+ Q+ A+K+L+ + E+E+ Q+L + + Q
Sbjct: 2020 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2079
Query: 77 GVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQ 121
E + +EA E + + Q R++EE + ++ E Q
Sbjct: 2080 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2124
Score = 32.3 bits (72), Expect = 0.27
Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 16/126 (12%)
Query: 12 QGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREI-------LTMEKEVAQ 64
Q + L +AEA+ R R Q +E L + AE++LR+ + + E AQ
Sbjct: 1512 QAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ 1571
Query: 65 SLLNAKEQVHQGGV--ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQE 122
A+ Q + + QLE LQE ++ QL E E + +A+ ER
Sbjct: 1572 RSAEAELQSKRASFAEKTAQLERSLQEE-------HVAVAQLREEAERRAQQQAEAERAR 1624
Query: 123 KEVDED 128
+E + +
Sbjct: 1625 EEAERE 1630
Score = 31.6 bits (70), Expect = 0.46
Identities = 24/95 (25%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQ 81
RAE +R + E++ E+L T+ ++++ + T+E + QS +A E++ + EL+
Sbjct: 2398 RAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDA-ERLREAIAELE 2456
Query: 82 QLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEA 116
+ + LQ+ + +LK+ +Q ++ + L+E +A
Sbjct: 2457 REKEKLQQEAKL-LQLKSEEMQTVQQEQLLQETQA 2490
Score = 31.2 bits (69), Expect = 0.60
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 18/119 (15%)
Query: 24 EAQQRRLL----GRHE-QVVERLLETQDGAEKQLR-------EILTMEKEVAQSLLNAK- 70
EA QRR L +H+ + ERL + + ++ +L + L ++V + +L K
Sbjct: 1873 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1932
Query: 71 --EQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDE 127
E+ G EL+ LE G + EDT +L E +++ A+ ER+ +E +E
Sbjct: 1933 SFEKAAAGKAELE-LELGRIRSNAEDTLRSKEQAEL--EAARQRQLAAEEERRRREAEE 1988
Score = 28.5 bits (62), Expect = 3.9
Identities = 34/134 (25%), Positives = 56/134 (41%), Gaps = 15/134 (11%)
Query: 5 RDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQ 64
R IE+ L L A+AQQ R E Q E++ + ++ +E +
Sbjct: 2507 RFIEQEKAKLEQLFQDEVAKAQQLR---------EEQQRQQQQMEQERQRLVASMEEARR 2557
Query: 65 SLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKE 124
A+E V + ELQQLE Q+ +++ L +L +L+ L+E +E
Sbjct: 2558 RQHEAEEGVRRKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2614
Query: 125 VDED---TTVTIPS 135
V T T+P+
Sbjct: 2615 VTASQVAATKTLPN 2628
Score = 28.1 bits (61), Expect = 5.0
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 25/123 (20%)
Query: 29 RLLGRHEQVVERLLETQDGAEKQLREI-------------LTMEKEVAQSLLNAKEQVHQ 75
RL + E+V ++ Q AEKQ E ++E+A+ L + Q+ +
Sbjct: 1643 RLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE 1702
Query: 76 GGV--------ELQQLEAGLQEAGEEDTRLKASLLQLTRE----LEELKEIEADLERQEK 123
G EL +L A ++ ++ L+ L +L RE ++ +E+EA+L +
Sbjct: 1703 GTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1762
Query: 124 EVD 126
E++
Sbjct: 1763 EME 1765
Score = 27.7 bits (60), Expect = 6.6
Identities = 29/135 (21%), Positives = 54/135 (40%), Gaps = 13/135 (9%)
Query: 20 ANRAEAQQRRLLGRHEQV------VERLLETQDGAEKQLREILTMEKEVAQSLLNAKE-- 71
A +AEA +R L E++ +E + GAE +L+ + +E A+E
Sbjct: 1437 ARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEA 1496
Query: 72 -----QVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVD 126
QV +Q E L + + + + LEEL+ + ER+ ++ +
Sbjct: 1497 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1556
Query: 127 EDTTVTIPSAVYVAQ 141
+ + A+ AQ
Sbjct: 1557 VERARQVQVALETAQ 1571
Score = 27.3 bits (59), Expect = 8.6
Identities = 37/136 (27%), Positives = 62/136 (45%), Gaps = 16/136 (11%)
Query: 4 FRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREI--LTMEKE 61
FR++ E + L +L EA+++R L + +R + AEK L I T K
Sbjct: 1796 FRELAEEAARLRALA----EEAKRQRQLAEEDAARQRAEAERVLAEK-LAAIGEATRLKT 1850
Query: 62 VAQSLLNAKEQVHQGGVELQQLEAGL-----QEAGEEDTRLKASLLQLTR----ELEELK 112
A+ L KE ++ L + EA ++A + ++ L QL + ELE K
Sbjct: 1851 EAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQK 1910
Query: 113 EIEADLERQEKEVDED 128
+ D RQ ++V+E+
Sbjct: 1911 GLVEDTLRQRRQVEEE 1926
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 47.8 bits (112), Expect = 6e-06
Identities = 35/118 (29%), Positives = 65/118 (55%), Gaps = 9/118 (7%)
Query: 20 ANRAEAQQRRLLGRHEQVVERLLETQDG-AEKQLREILTMEKEVAQSLLNAKEQVHQGGV 78
A RA+A+Q L R +Q + +E AE+ LR+ +E+E+ L +E HQ +
Sbjct: 2151 ARRAQAEQAAL--RQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNL 2208
Query: 79 ---ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEV---DEDTT 130
ELQ+L+A EA + ++++ L + ++EEL +++A +E + + + D+D T
Sbjct: 2209 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2266
Score = 40.4 bits (93), Expect = 0.001
Identities = 33/116 (28%), Positives = 60/116 (51%), Gaps = 8/116 (6%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLRE----ILTMEKEVAQSLLNAKEQVHQGG 77
R EA+ R L+ R + +R L+ + KQ+ E + +E A+ A+E + Q
Sbjct: 2250 RIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQR 2309
Query: 78 VELQQLEAGLQEAGEEDTRLK--ASLLQLTREL--EELKEIEADLERQEKEVDEDT 129
+++ +A +E TRLK A LLQ +EL E+ + ++ D E+ +++ E+T
Sbjct: 2310 ALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2365
Score = 35.4 bits (80), Expect = 0.032
Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 12/125 (9%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQ 81
R E ++R + + ERL E + EKQ +++A++ AK Q + ELQ
Sbjct: 1347 RMEEEERLAEQQRAEERERLAEVEAALEKQ--------RQLAEAHAQAKAQAEREAKELQ 1398
Query: 82 QL----EAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTTVTIPSAV 137
Q +EA + + K S+ + ++L + E E + ++ E E + + I +
Sbjct: 1399 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1458
Query: 138 YVAQL 142
V +L
Sbjct: 1459 RVVRL 1463
Score = 33.9 bits (76), Expect = 0.092
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 21/127 (16%)
Query: 23 AEAQQRRLLGRHEQVVERLLETQDG------AEKQLREILTMEKE--------VAQSLLN 68
A+ Q RRL EQ+ ++L E G AE+Q + ++ E E ++++
Sbjct: 2343 AQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQAR 2402
Query: 69 AKE-------QVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQ 121
A+E Q + G +L + E QE L+ Q + E L+E A+LER+
Sbjct: 2403 AEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELERE 2462
Query: 122 EKEVDED 128
++++ ++
Sbjct: 2463 KEKLQQE 2469
Score = 33.1 bits (74), Expect = 0.16
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 9/105 (8%)
Query: 26 QQRRLLGRHEQVVERLLE-TQDGAEKQLRE--------ILTMEKEVAQSLLNAKEQVHQG 76
+ RRL R EQ R L+ Q+ A+K+L+ + E+E+ Q+L + + Q
Sbjct: 2024 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2083
Query: 77 GVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQ 121
E + +EA E + + Q R++EE + ++ E Q
Sbjct: 2084 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2128
Score = 32.3 bits (72), Expect = 0.27
Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 16/126 (12%)
Query: 12 QGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREI-------LTMEKEVAQ 64
Q + L +AEA+ R R Q +E L + AE++LR+ + + E AQ
Sbjct: 1516 QAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ 1575
Query: 65 SLLNAKEQVHQGGV--ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQE 122
A+ Q + + QLE LQE ++ QL E E + +A+ ER
Sbjct: 1576 RSAEAELQSKRASFAEKTAQLERSLQEE-------HVAVAQLREEAERRAQQQAEAERAR 1628
Query: 123 KEVDED 128
+E + +
Sbjct: 1629 EEAERE 1634
Score = 31.6 bits (70), Expect = 0.46
Identities = 24/95 (25%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQ 81
RAE +R + E++ E+L T+ ++++ + T+E + QS +A E++ + EL+
Sbjct: 2402 RAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDA-ERLREAIAELE 2460
Query: 82 QLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEA 116
+ + LQ+ + +LK+ +Q ++ + L+E +A
Sbjct: 2461 REKEKLQQEAKL-LQLKSEEMQTVQQEQLLQETQA 2494
Score = 31.2 bits (69), Expect = 0.60
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 18/119 (15%)
Query: 24 EAQQRRLL----GRHE-QVVERLLETQDGAEKQLR-------EILTMEKEVAQSLLNAK- 70
EA QRR L +H+ + ERL + + ++ +L + L ++V + +L K
Sbjct: 1877 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1936
Query: 71 --EQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDE 127
E+ G EL+ LE G + EDT +L E +++ A+ ER+ +E +E
Sbjct: 1937 SFEKAAAGKAELE-LELGRIRSNAEDTLRSKEQAEL--EAARQRQLAAEEERRRREAEE 1992
Score = 28.5 bits (62), Expect = 3.9
Identities = 34/134 (25%), Positives = 56/134 (41%), Gaps = 15/134 (11%)
Query: 5 RDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQ 64
R IE+ L L A+AQQ R E Q E++ + ++ +E +
Sbjct: 2511 RFIEQEKAKLEQLFQDEVAKAQQLR---------EEQQRQQQQMEQERQRLVASMEEARR 2561
Query: 65 SLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKE 124
A+E V + ELQQLE Q+ +++ L +L +L+ L+E +E
Sbjct: 2562 RQHEAEEGVRRKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2618
Query: 125 VDED---TTVTIPS 135
V T T+P+
Sbjct: 2619 VTASQVAATKTLPN 2632
Score = 28.1 bits (61), Expect = 5.0
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 25/123 (20%)
Query: 29 RLLGRHEQVVERLLETQDGAEKQLREI-------------LTMEKEVAQSLLNAKEQVHQ 75
RL + E+V ++ Q AEKQ E ++E+A+ L + Q+ +
Sbjct: 1647 RLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE 1706
Query: 76 GGV--------ELQQLEAGLQEAGEEDTRLKASLLQLTRE----LEELKEIEADLERQEK 123
G EL +L A ++ ++ L+ L +L RE ++ +E+EA+L +
Sbjct: 1707 GTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1766
Query: 124 EVD 126
E++
Sbjct: 1767 EME 1769
Score = 27.7 bits (60), Expect = 6.6
Identities = 29/135 (21%), Positives = 54/135 (40%), Gaps = 13/135 (9%)
Query: 20 ANRAEAQQRRLLGRHEQV------VERLLETQDGAEKQLREILTMEKEVAQSLLNAKE-- 71
A +AEA +R L E++ +E + GAE +L+ + +E A+E
Sbjct: 1441 ARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEA 1500
Query: 72 -----QVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVD 126
QV +Q E L + + + + LEEL+ + ER+ ++ +
Sbjct: 1501 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1560
Query: 127 EDTTVTIPSAVYVAQ 141
+ + A+ AQ
Sbjct: 1561 VERARQVQVALETAQ 1575
Score = 27.3 bits (59), Expect = 8.6
Identities = 37/136 (27%), Positives = 62/136 (45%), Gaps = 16/136 (11%)
Query: 4 FRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREI--LTMEKE 61
FR++ E + L +L EA+++R L + +R + AEK L I T K
Sbjct: 1800 FRELAEEAARLRALA----EEAKRQRQLAEEDAARQRAEAERVLAEK-LAAIGEATRLKT 1854
Query: 62 VAQSLLNAKEQVHQGGVELQQLEAGL-----QEAGEEDTRLKASLLQLTR----ELEELK 112
A+ L KE ++ L + EA ++A + ++ L QL + ELE K
Sbjct: 1855 EAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQK 1914
Query: 113 EIEADLERQEKEVDED 128
+ D RQ ++V+E+
Sbjct: 1915 GLVEDTLRQRRQVEEE 1930
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 47.8 bits (112), Expect = 6e-06
Identities = 35/118 (29%), Positives = 65/118 (55%), Gaps = 9/118 (7%)
Query: 20 ANRAEAQQRRLLGRHEQVVERLLETQDG-AEKQLREILTMEKEVAQSLLNAKEQVHQGGV 78
A RA+A+Q L R +Q + +E AE+ LR+ +E+E+ L +E HQ +
Sbjct: 2147 ARRAQAEQAAL--RQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNL 2204
Query: 79 ---ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEV---DEDTT 130
ELQ+L+A EA + ++++ L + ++EEL +++A +E + + + D+D T
Sbjct: 2205 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2262
Score = 40.4 bits (93), Expect = 0.001
Identities = 33/116 (28%), Positives = 60/116 (51%), Gaps = 8/116 (6%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLRE----ILTMEKEVAQSLLNAKEQVHQGG 77
R EA+ R L+ R + +R L+ + KQ+ E + +E A+ A+E + Q
Sbjct: 2246 RIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQR 2305
Query: 78 VELQQLEAGLQEAGEEDTRLK--ASLLQLTREL--EELKEIEADLERQEKEVDEDT 129
+++ +A +E TRLK A LLQ +EL E+ + ++ D E+ +++ E+T
Sbjct: 2306 ALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2361
Score = 35.4 bits (80), Expect = 0.032
Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 12/125 (9%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQ 81
R E ++R + + ERL E + EKQ +++A++ AK Q + ELQ
Sbjct: 1343 RMEEEERLAEQQRAEERERLAEVEAALEKQ--------RQLAEAHAQAKAQAEREAKELQ 1394
Query: 82 QL----EAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTTVTIPSAV 137
Q +EA + + K S+ + ++L + E E + ++ E E + + I +
Sbjct: 1395 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1454
Query: 138 YVAQL 142
V +L
Sbjct: 1455 RVVRL 1459
Score = 33.9 bits (76), Expect = 0.092
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 21/127 (16%)
Query: 23 AEAQQRRLLGRHEQVVERLLETQDG------AEKQLREILTMEKE--------VAQSLLN 68
A+ Q RRL EQ+ ++L E G AE+Q + ++ E E ++++
Sbjct: 2339 AQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQAR 2398
Query: 69 AKE-------QVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQ 121
A+E Q + G +L + E QE L+ Q + E L+E A+LER+
Sbjct: 2399 AEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELERE 2458
Query: 122 EKEVDED 128
++++ ++
Sbjct: 2459 KEKLQQE 2465
Score = 33.1 bits (74), Expect = 0.16
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 9/105 (8%)
Query: 26 QQRRLLGRHEQVVERLLE-TQDGAEKQLRE--------ILTMEKEVAQSLLNAKEQVHQG 76
+ RRL R EQ R L+ Q+ A+K+L+ + E+E+ Q+L + + Q
Sbjct: 2020 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2079
Query: 77 GVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQ 121
E + +EA E + + Q R++EE + ++ E Q
Sbjct: 2080 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2124
Score = 32.3 bits (72), Expect = 0.27
Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 16/126 (12%)
Query: 12 QGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREI-------LTMEKEVAQ 64
Q + L +AEA+ R R Q +E L + AE++LR+ + + E AQ
Sbjct: 1512 QAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ 1571
Query: 65 SLLNAKEQVHQGGV--ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQE 122
A+ Q + + QLE LQE ++ QL E E + +A+ ER
Sbjct: 1572 RSAEAELQSKRASFAEKTAQLERSLQEE-------HVAVAQLREEAERRAQQQAEAERAR 1624
Query: 123 KEVDED 128
+E + +
Sbjct: 1625 EEAERE 1630
Score = 31.6 bits (70), Expect = 0.46
Identities = 24/95 (25%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQ 81
RAE +R + E++ E+L T+ ++++ + T+E + QS +A E++ + EL+
Sbjct: 2398 RAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDA-ERLREAIAELE 2456
Query: 82 QLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEA 116
+ + LQ+ + +LK+ +Q ++ + L+E +A
Sbjct: 2457 REKEKLQQEAKL-LQLKSEEMQTVQQEQLLQETQA 2490
Score = 31.2 bits (69), Expect = 0.60
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 18/119 (15%)
Query: 24 EAQQRRLL----GRHE-QVVERLLETQDGAEKQLR-------EILTMEKEVAQSLLNAK- 70
EA QRR L +H+ + ERL + + ++ +L + L ++V + +L K
Sbjct: 1873 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1932
Query: 71 --EQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDE 127
E+ G EL+ LE G + EDT +L E +++ A+ ER+ +E +E
Sbjct: 1933 SFEKAAAGKAELE-LELGRIRSNAEDTLRSKEQAEL--EAARQRQLAAEEERRRREAEE 1988
Score = 28.5 bits (62), Expect = 3.9
Identities = 34/134 (25%), Positives = 56/134 (41%), Gaps = 15/134 (11%)
Query: 5 RDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQ 64
R IE+ L L A+AQQ R E Q E++ + ++ +E +
Sbjct: 2507 RFIEQEKAKLEQLFQDEVAKAQQLR---------EEQQRQQQQMEQERQRLVASMEEARR 2557
Query: 65 SLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKE 124
A+E V + ELQQLE Q+ +++ L +L +L+ L+E +E
Sbjct: 2558 RQHEAEEGVRRKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2614
Query: 125 VDED---TTVTIPS 135
V T T+P+
Sbjct: 2615 VTASQVAATKTLPN 2628
Score = 28.1 bits (61), Expect = 5.0
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 25/123 (20%)
Query: 29 RLLGRHEQVVERLLETQDGAEKQLREI-------------LTMEKEVAQSLLNAKEQVHQ 75
RL + E+V ++ Q AEKQ E ++E+A+ L + Q+ +
Sbjct: 1643 RLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE 1702
Query: 76 GGV--------ELQQLEAGLQEAGEEDTRLKASLLQLTRE----LEELKEIEADLERQEK 123
G EL +L A ++ ++ L+ L +L RE ++ +E+EA+L +
Sbjct: 1703 GTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1762
Query: 124 EVD 126
E++
Sbjct: 1763 EME 1765
Score = 27.7 bits (60), Expect = 6.6
Identities = 29/135 (21%), Positives = 54/135 (40%), Gaps = 13/135 (9%)
Query: 20 ANRAEAQQRRLLGRHEQV------VERLLETQDGAEKQLREILTMEKEVAQSLLNAKE-- 71
A +AEA +R L E++ +E + GAE +L+ + +E A+E
Sbjct: 1437 ARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEA 1496
Query: 72 -----QVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVD 126
QV +Q E L + + + + LEEL+ + ER+ ++ +
Sbjct: 1497 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1556
Query: 127 EDTTVTIPSAVYVAQ 141
+ + A+ AQ
Sbjct: 1557 VERARQVQVALETAQ 1571
Score = 27.3 bits (59), Expect = 8.6
Identities = 37/136 (27%), Positives = 62/136 (45%), Gaps = 16/136 (11%)
Query: 4 FRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREI--LTMEKE 61
FR++ E + L +L EA+++R L + +R + AEK L I T K
Sbjct: 1796 FRELAEEAARLRALA----EEAKRQRQLAEEDAARQRAEAERVLAEK-LAAIGEATRLKT 1850
Query: 62 VAQSLLNAKEQVHQGGVELQQLEAGL-----QEAGEEDTRLKASLLQLTR----ELEELK 112
A+ L KE ++ L + EA ++A + ++ L QL + ELE K
Sbjct: 1851 EAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQK 1910
Query: 113 EIEADLERQEKEVDED 128
+ D RQ ++V+E+
Sbjct: 1911 GLVEDTLRQRRQVEEE 1926
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 47.8 bits (112), Expect = 6e-06
Identities = 35/118 (29%), Positives = 65/118 (55%), Gaps = 9/118 (7%)
Query: 20 ANRAEAQQRRLLGRHEQVVERLLETQDG-AEKQLREILTMEKEVAQSLLNAKEQVHQGGV 78
A RA+A+Q L R +Q + +E AE+ LR+ +E+E+ L +E HQ +
Sbjct: 2115 ARRAQAEQAAL--RQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNL 2172
Query: 79 ---ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEV---DEDTT 130
ELQ+L+A EA + ++++ L + ++EEL +++A +E + + + D+D T
Sbjct: 2173 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2230
Score = 40.4 bits (93), Expect = 0.001
Identities = 33/116 (28%), Positives = 60/116 (51%), Gaps = 8/116 (6%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLRE----ILTMEKEVAQSLLNAKEQVHQGG 77
R EA+ R L+ R + +R L+ + KQ+ E + +E A+ A+E + Q
Sbjct: 2214 RIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQR 2273
Query: 78 VELQQLEAGLQEAGEEDTRLK--ASLLQLTREL--EELKEIEADLERQEKEVDEDT 129
+++ +A +E TRLK A LLQ +EL E+ + ++ D E+ +++ E+T
Sbjct: 2274 ALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2329
Score = 35.4 bits (80), Expect = 0.032
Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 12/125 (9%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQ 81
R E ++R + + ERL E + EKQ +++A++ AK Q + ELQ
Sbjct: 1311 RMEEEERLAEQQRAEERERLAEVEAALEKQ--------RQLAEAHAQAKAQAEREAKELQ 1362
Query: 82 QL----EAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTTVTIPSAV 137
Q +EA + + K S+ + ++L + E E + ++ E E + + I +
Sbjct: 1363 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1422
Query: 138 YVAQL 142
V +L
Sbjct: 1423 RVVRL 1427
Score = 33.9 bits (76), Expect = 0.092
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 21/127 (16%)
Query: 23 AEAQQRRLLGRHEQVVERLLETQDG------AEKQLREILTMEKE--------VAQSLLN 68
A+ Q RRL EQ+ ++L E G AE+Q + ++ E E ++++
Sbjct: 2307 AQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQAR 2366
Query: 69 AKE-------QVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQ 121
A+E Q + G +L + E QE L+ Q + E L+E A+LER+
Sbjct: 2367 AEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELERE 2426
Query: 122 EKEVDED 128
++++ ++
Sbjct: 2427 KEKLQQE 2433
Score = 33.1 bits (74), Expect = 0.16
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 9/105 (8%)
Query: 26 QQRRLLGRHEQVVERLLE-TQDGAEKQLRE--------ILTMEKEVAQSLLNAKEQVHQG 76
+ RRL R EQ R L+ Q+ A+K+L+ + E+E+ Q+L + + Q
Sbjct: 1988 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2047
Query: 77 GVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQ 121
E + +EA E + + Q R++EE + ++ E Q
Sbjct: 2048 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2092
Score = 32.3 bits (72), Expect = 0.27
Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 16/126 (12%)
Query: 12 QGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREI-------LTMEKEVAQ 64
Q + L +AEA+ R R Q +E L + AE++LR+ + + E AQ
Sbjct: 1480 QAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ 1539
Query: 65 SLLNAKEQVHQGGV--ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQE 122
A+ Q + + QLE LQE ++ QL E E + +A+ ER
Sbjct: 1540 RSAEAELQSKRASFAEKTAQLERSLQEE-------HVAVAQLREEAERRAQQQAEAERAR 1592
Query: 123 KEVDED 128
+E + +
Sbjct: 1593 EEAERE 1598
Score = 31.6 bits (70), Expect = 0.46
Identities = 24/95 (25%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQ 81
RAE +R + E++ E+L T+ ++++ + T+E + QS +A E++ + EL+
Sbjct: 2366 RAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDA-ERLREAIAELE 2424
Query: 82 QLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEA 116
+ + LQ+ + +LK+ +Q ++ + L+E +A
Sbjct: 2425 REKEKLQQEAKL-LQLKSEEMQTVQQEQLLQETQA 2458
Score = 31.2 bits (69), Expect = 0.60
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 18/119 (15%)
Query: 24 EAQQRRLL----GRHE-QVVERLLETQDGAEKQLR-------EILTMEKEVAQSLLNAK- 70
EA QRR L +H+ + ERL + + ++ +L + L ++V + +L K
Sbjct: 1841 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1900
Query: 71 --EQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDE 127
E+ G EL+ LE G + EDT +L E +++ A+ ER+ +E +E
Sbjct: 1901 SFEKAAAGKAELE-LELGRIRSNAEDTLRSKEQAEL--EAARQRQLAAEEERRRREAEE 1956
Score = 28.5 bits (62), Expect = 3.9
Identities = 34/134 (25%), Positives = 56/134 (41%), Gaps = 15/134 (11%)
Query: 5 RDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQ 64
R IE+ L L A+AQQ R E Q E++ + ++ +E +
Sbjct: 2475 RFIEQEKAKLEQLFQDEVAKAQQLR---------EEQQRQQQQMEQERQRLVASMEEARR 2525
Query: 65 SLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKE 124
A+E V + ELQQLE Q+ +++ L +L +L+ L+E +E
Sbjct: 2526 RQHEAEEGVRRKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2582
Query: 125 VDED---TTVTIPS 135
V T T+P+
Sbjct: 2583 VTASQVAATKTLPN 2596
Score = 28.1 bits (61), Expect = 5.0
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 25/123 (20%)
Query: 29 RLLGRHEQVVERLLETQDGAEKQLREI-------------LTMEKEVAQSLLNAKEQVHQ 75
RL + E+V ++ Q AEKQ E ++E+A+ L + Q+ +
Sbjct: 1611 RLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE 1670
Query: 76 GGV--------ELQQLEAGLQEAGEEDTRLKASLLQLTRE----LEELKEIEADLERQEK 123
G EL +L A ++ ++ L+ L +L RE ++ +E+EA+L +
Sbjct: 1671 GTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1730
Query: 124 EVD 126
E++
Sbjct: 1731 EME 1733
Score = 27.7 bits (60), Expect = 6.6
Identities = 29/135 (21%), Positives = 54/135 (40%), Gaps = 13/135 (9%)
Query: 20 ANRAEAQQRRLLGRHEQV------VERLLETQDGAEKQLREILTMEKEVAQSLLNAKE-- 71
A +AEA +R L E++ +E + GAE +L+ + +E A+E
Sbjct: 1405 ARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEA 1464
Query: 72 -----QVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVD 126
QV +Q E L + + + + LEEL+ + ER+ ++ +
Sbjct: 1465 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1524
Query: 127 EDTTVTIPSAVYVAQ 141
+ + A+ AQ
Sbjct: 1525 VERARQVQVALETAQ 1539
Score = 27.3 bits (59), Expect = 8.6
Identities = 37/136 (27%), Positives = 62/136 (45%), Gaps = 16/136 (11%)
Query: 4 FRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREI--LTMEKE 61
FR++ E + L +L EA+++R L + +R + AEK L I T K
Sbjct: 1764 FRELAEEAARLRALA----EEAKRQRQLAEEDAARQRAEAERVLAEK-LAAIGEATRLKT 1818
Query: 62 VAQSLLNAKEQVHQGGVELQQLEAGL-----QEAGEEDTRLKASLLQLTR----ELEELK 112
A+ L KE ++ L + EA ++A + ++ L QL + ELE K
Sbjct: 1819 EAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQK 1878
Query: 113 EIEADLERQEKEVDED 128
+ D RQ ++V+E+
Sbjct: 1879 GLVEDTLRQRRQVEEE 1894
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 47.8 bits (112), Expect = 6e-06
Identities = 35/118 (29%), Positives = 65/118 (55%), Gaps = 9/118 (7%)
Query: 20 ANRAEAQQRRLLGRHEQVVERLLETQDG-AEKQLREILTMEKEVAQSLLNAKEQVHQGGV 78
A RA+A+Q L R +Q + +E AE+ LR+ +E+E+ L +E HQ +
Sbjct: 2284 ARRAQAEQAAL--RQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNL 2341
Query: 79 ---ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEV---DEDTT 130
ELQ+L+A EA + ++++ L + ++EEL +++A +E + + + D+D T
Sbjct: 2342 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2399
Score = 40.4 bits (93), Expect = 0.001
Identities = 33/116 (28%), Positives = 60/116 (51%), Gaps = 8/116 (6%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLRE----ILTMEKEVAQSLLNAKEQVHQGG 77
R EA+ R L+ R + +R L+ + KQ+ E + +E A+ A+E + Q
Sbjct: 2383 RIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQR 2442
Query: 78 VELQQLEAGLQEAGEEDTRLK--ASLLQLTREL--EELKEIEADLERQEKEVDEDT 129
+++ +A +E TRLK A LLQ +EL E+ + ++ D E+ +++ E+T
Sbjct: 2443 ALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2498
Score = 35.4 bits (80), Expect = 0.032
Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 12/125 (9%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQ 81
R E ++R + + ERL E + EKQ +++A++ AK Q + ELQ
Sbjct: 1480 RMEEEERLAEQQRAEERERLAEVEAALEKQ--------RQLAEAHAQAKAQAEREAKELQ 1531
Query: 82 QL----EAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTTVTIPSAV 137
Q +EA + + K S+ + ++L + E E + ++ E E + + I +
Sbjct: 1532 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1591
Query: 138 YVAQL 142
V +L
Sbjct: 1592 RVVRL 1596
Score = 33.9 bits (76), Expect = 0.092
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 21/127 (16%)
Query: 23 AEAQQRRLLGRHEQVVERLLETQDG------AEKQLREILTMEKE--------VAQSLLN 68
A+ Q RRL EQ+ ++L E G AE+Q + ++ E E ++++
Sbjct: 2476 AQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQAR 2535
Query: 69 AKE-------QVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQ 121
A+E Q + G +L + E QE L+ Q + E L+E A+LER+
Sbjct: 2536 AEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELERE 2595
Query: 122 EKEVDED 128
++++ ++
Sbjct: 2596 KEKLQQE 2602
Score = 33.1 bits (74), Expect = 0.16
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 9/105 (8%)
Query: 26 QQRRLLGRHEQVVERLLE-TQDGAEKQLRE--------ILTMEKEVAQSLLNAKEQVHQG 76
+ RRL R EQ R L+ Q+ A+K+L+ + E+E+ Q+L + + Q
Sbjct: 2157 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2216
Query: 77 GVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQ 121
E + +EA E + + Q R++EE + ++ E Q
Sbjct: 2217 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2261
Score = 32.3 bits (72), Expect = 0.27
Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 16/126 (12%)
Query: 12 QGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREI-------LTMEKEVAQ 64
Q + L +AEA+ R R Q +E L + AE++LR+ + + E AQ
Sbjct: 1649 QAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ 1708
Query: 65 SLLNAKEQVHQGGV--ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQE 122
A+ Q + + QLE LQE ++ QL E E + +A+ ER
Sbjct: 1709 RSAEAELQSKRASFAEKTAQLERSLQEE-------HVAVAQLREEAERRAQQQAEAERAR 1761
Query: 123 KEVDED 128
+E + +
Sbjct: 1762 EEAERE 1767
Score = 31.6 bits (70), Expect = 0.46
Identities = 24/95 (25%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQ 81
RAE +R + E++ E+L T+ ++++ + T+E + QS +A E++ + EL+
Sbjct: 2535 RAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDA-ERLREAIAELE 2593
Query: 82 QLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEA 116
+ + LQ+ + +LK+ +Q ++ + L+E +A
Sbjct: 2594 REKEKLQQEAKL-LQLKSEEMQTVQQEQLLQETQA 2627
Score = 31.2 bits (69), Expect = 0.60
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 18/119 (15%)
Query: 24 EAQQRRLL----GRHE-QVVERLLETQDGAEKQLR-------EILTMEKEVAQSLLNAK- 70
EA QRR L +H+ + ERL + + ++ +L + L ++V + +L K
Sbjct: 2010 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 2069
Query: 71 --EQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDE 127
E+ G EL+ LE G + EDT +L E +++ A+ ER+ +E +E
Sbjct: 2070 SFEKAAAGKAELE-LELGRIRSNAEDTLRSKEQAEL--EAARQRQLAAEEERRRREAEE 2125
Score = 28.5 bits (62), Expect = 3.9
Identities = 34/134 (25%), Positives = 56/134 (41%), Gaps = 15/134 (11%)
Query: 5 RDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQ 64
R IE+ L L A+AQQ R E Q E++ + ++ +E +
Sbjct: 2644 RFIEQEKAKLEQLFQDEVAKAQQLR---------EEQQRQQQQMEQERQRLVASMEEARR 2694
Query: 65 SLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKE 124
A+E V + ELQQLE Q+ +++ L +L +L+ L+E +E
Sbjct: 2695 RQHEAEEGVRRKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2751
Query: 125 VDED---TTVTIPS 135
V T T+P+
Sbjct: 2752 VTASQVAATKTLPN 2765
Score = 28.1 bits (61), Expect = 5.0
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 25/123 (20%)
Query: 29 RLLGRHEQVVERLLETQDGAEKQLREI-------------LTMEKEVAQSLLNAKEQVHQ 75
RL + E+V ++ Q AEKQ E ++E+A+ L + Q+ +
Sbjct: 1780 RLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE 1839
Query: 76 GGV--------ELQQLEAGLQEAGEEDTRLKASLLQLTRE----LEELKEIEADLERQEK 123
G EL +L A ++ ++ L+ L +L RE ++ +E+EA+L +
Sbjct: 1840 GTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1899
Query: 124 EVD 126
E++
Sbjct: 1900 EME 1902
Score = 27.7 bits (60), Expect = 6.6
Identities = 29/135 (21%), Positives = 54/135 (40%), Gaps = 13/135 (9%)
Query: 20 ANRAEAQQRRLLGRHEQV------VERLLETQDGAEKQLREILTMEKEVAQSLLNAKE-- 71
A +AEA +R L E++ +E + GAE +L+ + +E A+E
Sbjct: 1574 ARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEA 1633
Query: 72 -----QVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVD 126
QV +Q E L + + + + LEEL+ + ER+ ++ +
Sbjct: 1634 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1693
Query: 127 EDTTVTIPSAVYVAQ 141
+ + A+ AQ
Sbjct: 1694 VERARQVQVALETAQ 1708
Score = 27.3 bits (59), Expect = 8.6
Identities = 37/136 (27%), Positives = 62/136 (45%), Gaps = 16/136 (11%)
Query: 4 FRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREI--LTMEKE 61
FR++ E + L +L EA+++R L + +R + AEK L I T K
Sbjct: 1933 FRELAEEAARLRALA----EEAKRQRQLAEEDAARQRAEAERVLAEK-LAAIGEATRLKT 1987
Query: 62 VAQSLLNAKEQVHQGGVELQQLEAGL-----QEAGEEDTRLKASLLQLTR----ELEELK 112
A+ L KE ++ L + EA ++A + ++ L QL + ELE K
Sbjct: 1988 EAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQK 2047
Query: 113 EIEADLERQEKEVDED 128
+ D RQ ++V+E+
Sbjct: 2048 GLVEDTLRQRRQVEEE 2063
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 47.8 bits (112), Expect = 6e-06
Identities = 35/118 (29%), Positives = 65/118 (55%), Gaps = 9/118 (7%)
Query: 20 ANRAEAQQRRLLGRHEQVVERLLETQDG-AEKQLREILTMEKEVAQSLLNAKEQVHQGGV 78
A RA+A+Q L R +Q + +E AE+ LR+ +E+E+ L +E HQ +
Sbjct: 2125 ARRAQAEQAAL--RQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNL 2182
Query: 79 ---ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEV---DEDTT 130
ELQ+L+A EA + ++++ L + ++EEL +++A +E + + + D+D T
Sbjct: 2183 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2240
Score = 40.4 bits (93), Expect = 0.001
Identities = 33/116 (28%), Positives = 60/116 (51%), Gaps = 8/116 (6%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLRE----ILTMEKEVAQSLLNAKEQVHQGG 77
R EA+ R L+ R + +R L+ + KQ+ E + +E A+ A+E + Q
Sbjct: 2224 RIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQR 2283
Query: 78 VELQQLEAGLQEAGEEDTRLK--ASLLQLTREL--EELKEIEADLERQEKEVDEDT 129
+++ +A +E TRLK A LLQ +EL E+ + ++ D E+ +++ E+T
Sbjct: 2284 ALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2339
Score = 35.4 bits (80), Expect = 0.032
Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 12/125 (9%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQ 81
R E ++R + + ERL E + EKQ +++A++ AK Q + ELQ
Sbjct: 1321 RMEEEERLAEQQRAEERERLAEVEAALEKQ--------RQLAEAHAQAKAQAEREAKELQ 1372
Query: 82 QL----EAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTTVTIPSAV 137
Q +EA + + K S+ + ++L + E E + ++ E E + + I +
Sbjct: 1373 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1432
Query: 138 YVAQL 142
V +L
Sbjct: 1433 RVVRL 1437
Score = 33.9 bits (76), Expect = 0.092
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 21/127 (16%)
Query: 23 AEAQQRRLLGRHEQVVERLLETQDG------AEKQLREILTMEKE--------VAQSLLN 68
A+ Q RRL EQ+ ++L E G AE+Q + ++ E E ++++
Sbjct: 2317 AQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQAR 2376
Query: 69 AKE-------QVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQ 121
A+E Q + G +L + E QE L+ Q + E L+E A+LER+
Sbjct: 2377 AEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELERE 2436
Query: 122 EKEVDED 128
++++ ++
Sbjct: 2437 KEKLQQE 2443
Score = 33.1 bits (74), Expect = 0.16
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 9/105 (8%)
Query: 26 QQRRLLGRHEQVVERLLE-TQDGAEKQLRE--------ILTMEKEVAQSLLNAKEQVHQG 76
+ RRL R EQ R L+ Q+ A+K+L+ + E+E+ Q+L + + Q
Sbjct: 1998 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2057
Query: 77 GVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQ 121
E + +EA E + + Q R++EE + ++ E Q
Sbjct: 2058 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2102
Score = 32.3 bits (72), Expect = 0.27
Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 16/126 (12%)
Query: 12 QGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREI-------LTMEKEVAQ 64
Q + L +AEA+ R R Q +E L + AE++LR+ + + E AQ
Sbjct: 1490 QAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ 1549
Query: 65 SLLNAKEQVHQGGV--ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQE 122
A+ Q + + QLE LQE ++ QL E E + +A+ ER
Sbjct: 1550 RSAEAELQSKRASFAEKTAQLERSLQEE-------HVAVAQLREEAERRAQQQAEAERAR 1602
Query: 123 KEVDED 128
+E + +
Sbjct: 1603 EEAERE 1608
Score = 31.6 bits (70), Expect = 0.46
Identities = 24/95 (25%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQ 81
RAE +R + E++ E+L T+ ++++ + T+E + QS +A E++ + EL+
Sbjct: 2376 RAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDA-ERLREAIAELE 2434
Query: 82 QLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEA 116
+ + LQ+ + +LK+ +Q ++ + L+E +A
Sbjct: 2435 REKEKLQQEAKL-LQLKSEEMQTVQQEQLLQETQA 2468
Score = 31.2 bits (69), Expect = 0.60
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 18/119 (15%)
Query: 24 EAQQRRLL----GRHE-QVVERLLETQDGAEKQLR-------EILTMEKEVAQSLLNAK- 70
EA QRR L +H+ + ERL + + ++ +L + L ++V + +L K
Sbjct: 1851 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1910
Query: 71 --EQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDE 127
E+ G EL+ LE G + EDT +L E +++ A+ ER+ +E +E
Sbjct: 1911 SFEKAAAGKAELE-LELGRIRSNAEDTLRSKEQAEL--EAARQRQLAAEEERRRREAEE 1966
Score = 28.5 bits (62), Expect = 3.9
Identities = 34/134 (25%), Positives = 56/134 (41%), Gaps = 15/134 (11%)
Query: 5 RDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQ 64
R IE+ L L A+AQQ R E Q E++ + ++ +E +
Sbjct: 2485 RFIEQEKAKLEQLFQDEVAKAQQLR---------EEQQRQQQQMEQERQRLVASMEEARR 2535
Query: 65 SLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKE 124
A+E V + ELQQLE Q+ +++ L +L +L+ L+E +E
Sbjct: 2536 RQHEAEEGVRRKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2592
Query: 125 VDED---TTVTIPS 135
V T T+P+
Sbjct: 2593 VTASQVAATKTLPN 2606
Score = 28.1 bits (61), Expect = 5.0
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 25/123 (20%)
Query: 29 RLLGRHEQVVERLLETQDGAEKQLREI-------------LTMEKEVAQSLLNAKEQVHQ 75
RL + E+V ++ Q AEKQ E ++E+A+ L + Q+ +
Sbjct: 1621 RLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE 1680
Query: 76 GGV--------ELQQLEAGLQEAGEEDTRLKASLLQLTRE----LEELKEIEADLERQEK 123
G EL +L A ++ ++ L+ L +L RE ++ +E+EA+L +
Sbjct: 1681 GTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1740
Query: 124 EVD 126
E++
Sbjct: 1741 EME 1743
Score = 27.7 bits (60), Expect = 6.6
Identities = 29/135 (21%), Positives = 54/135 (40%), Gaps = 13/135 (9%)
Query: 20 ANRAEAQQRRLLGRHEQV------VERLLETQDGAEKQLREILTMEKEVAQSLLNAKE-- 71
A +AEA +R L E++ +E + GAE +L+ + +E A+E
Sbjct: 1415 ARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEA 1474
Query: 72 -----QVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVD 126
QV +Q E L + + + + LEEL+ + ER+ ++ +
Sbjct: 1475 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1534
Query: 127 EDTTVTIPSAVYVAQ 141
+ + A+ AQ
Sbjct: 1535 VERARQVQVALETAQ 1549
Score = 27.3 bits (59), Expect = 8.6
Identities = 37/136 (27%), Positives = 62/136 (45%), Gaps = 16/136 (11%)
Query: 4 FRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREI--LTMEKE 61
FR++ E + L +L EA+++R L + +R + AEK L I T K
Sbjct: 1774 FRELAEEAARLRALA----EEAKRQRQLAEEDAARQRAEAERVLAEK-LAAIGEATRLKT 1828
Query: 62 VAQSLLNAKEQVHQGGVELQQLEAGL-----QEAGEEDTRLKASLLQLTR----ELEELK 112
A+ L KE ++ L + EA ++A + ++ L QL + ELE K
Sbjct: 1829 EAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQK 1888
Query: 113 EIEADLERQEKEVDED 128
+ D RQ ++V+E+
Sbjct: 1889 GLVEDTLRQRRQVEEE 1904
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 47.8 bits (112), Expect = 6e-06
Identities = 35/118 (29%), Positives = 65/118 (55%), Gaps = 9/118 (7%)
Query: 20 ANRAEAQQRRLLGRHEQVVERLLETQDG-AEKQLREILTMEKEVAQSLLNAKEQVHQGGV 78
A RA+A+Q L R +Q + +E AE+ LR+ +E+E+ L +E HQ +
Sbjct: 2133 ARRAQAEQAAL--RQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNL 2190
Query: 79 ---ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEV---DEDTT 130
ELQ+L+A EA + ++++ L + ++EEL +++A +E + + + D+D T
Sbjct: 2191 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2248
Score = 40.4 bits (93), Expect = 0.001
Identities = 33/116 (28%), Positives = 60/116 (51%), Gaps = 8/116 (6%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLRE----ILTMEKEVAQSLLNAKEQVHQGG 77
R EA+ R L+ R + +R L+ + KQ+ E + +E A+ A+E + Q
Sbjct: 2232 RIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQR 2291
Query: 78 VELQQLEAGLQEAGEEDTRLK--ASLLQLTREL--EELKEIEADLERQEKEVDEDT 129
+++ +A +E TRLK A LLQ +EL E+ + ++ D E+ +++ E+T
Sbjct: 2292 ALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2347
Score = 35.4 bits (80), Expect = 0.032
Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 12/125 (9%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQ 81
R E ++R + + ERL E + EKQ +++A++ AK Q + ELQ
Sbjct: 1329 RMEEEERLAEQQRAEERERLAEVEAALEKQ--------RQLAEAHAQAKAQAEREAKELQ 1380
Query: 82 QL----EAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTTVTIPSAV 137
Q +EA + + K S+ + ++L + E E + ++ E E + + I +
Sbjct: 1381 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1440
Query: 138 YVAQL 142
V +L
Sbjct: 1441 RVVRL 1445
Score = 33.9 bits (76), Expect = 0.092
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 21/127 (16%)
Query: 23 AEAQQRRLLGRHEQVVERLLETQDG------AEKQLREILTMEKE--------VAQSLLN 68
A+ Q RRL EQ+ ++L E G AE+Q + ++ E E ++++
Sbjct: 2325 AQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQAR 2384
Query: 69 AKE-------QVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQ 121
A+E Q + G +L + E QE L+ Q + E L+E A+LER+
Sbjct: 2385 AEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELERE 2444
Query: 122 EKEVDED 128
++++ ++
Sbjct: 2445 KEKLQQE 2451
Score = 33.1 bits (74), Expect = 0.16
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 9/105 (8%)
Query: 26 QQRRLLGRHEQVVERLLE-TQDGAEKQLRE--------ILTMEKEVAQSLLNAKEQVHQG 76
+ RRL R EQ R L+ Q+ A+K+L+ + E+E+ Q+L + + Q
Sbjct: 2006 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2065
Query: 77 GVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQ 121
E + +EA E + + Q R++EE + ++ E Q
Sbjct: 2066 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2110
Score = 32.3 bits (72), Expect = 0.27
Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 16/126 (12%)
Query: 12 QGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREI-------LTMEKEVAQ 64
Q + L +AEA+ R R Q +E L + AE++LR+ + + E AQ
Sbjct: 1498 QAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ 1557
Query: 65 SLLNAKEQVHQGGV--ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQE 122
A+ Q + + QLE LQE ++ QL E E + +A+ ER
Sbjct: 1558 RSAEAELQSKRASFAEKTAQLERSLQEE-------HVAVAQLREEAERRAQQQAEAERAR 1610
Query: 123 KEVDED 128
+E + +
Sbjct: 1611 EEAERE 1616
Score = 31.6 bits (70), Expect = 0.46
Identities = 24/95 (25%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQ 81
RAE +R + E++ E+L T+ ++++ + T+E + QS +A E++ + EL+
Sbjct: 2384 RAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDA-ERLREAIAELE 2442
Query: 82 QLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEA 116
+ + LQ+ + +LK+ +Q ++ + L+E +A
Sbjct: 2443 REKEKLQQEAKL-LQLKSEEMQTVQQEQLLQETQA 2476
Score = 31.2 bits (69), Expect = 0.60
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 18/119 (15%)
Query: 24 EAQQRRLL----GRHE-QVVERLLETQDGAEKQLR-------EILTMEKEVAQSLLNAK- 70
EA QRR L +H+ + ERL + + ++ +L + L ++V + +L K
Sbjct: 1859 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1918
Query: 71 --EQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDE 127
E+ G EL+ LE G + EDT +L E +++ A+ ER+ +E +E
Sbjct: 1919 SFEKAAAGKAELE-LELGRIRSNAEDTLRSKEQAEL--EAARQRQLAAEEERRRREAEE 1974
Score = 28.5 bits (62), Expect = 3.9
Identities = 34/134 (25%), Positives = 56/134 (41%), Gaps = 15/134 (11%)
Query: 5 RDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQ 64
R IE+ L L A+AQQ R E Q E++ + ++ +E +
Sbjct: 2493 RFIEQEKAKLEQLFQDEVAKAQQLR---------EEQQRQQQQMEQERQRLVASMEEARR 2543
Query: 65 SLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKE 124
A+E V + ELQQLE Q+ +++ L +L +L+ L+E +E
Sbjct: 2544 RQHEAEEGVRRKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2600
Query: 125 VDED---TTVTIPS 135
V T T+P+
Sbjct: 2601 VTASQVAATKTLPN 2614
Score = 28.1 bits (61), Expect = 5.0
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 25/123 (20%)
Query: 29 RLLGRHEQVVERLLETQDGAEKQLREI-------------LTMEKEVAQSLLNAKEQVHQ 75
RL + E+V ++ Q AEKQ E ++E+A+ L + Q+ +
Sbjct: 1629 RLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE 1688
Query: 76 GGV--------ELQQLEAGLQEAGEEDTRLKASLLQLTRE----LEELKEIEADLERQEK 123
G EL +L A ++ ++ L+ L +L RE ++ +E+EA+L +
Sbjct: 1689 GTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1748
Query: 124 EVD 126
E++
Sbjct: 1749 EME 1751
Score = 27.7 bits (60), Expect = 6.6
Identities = 29/135 (21%), Positives = 54/135 (40%), Gaps = 13/135 (9%)
Query: 20 ANRAEAQQRRLLGRHEQV------VERLLETQDGAEKQLREILTMEKEVAQSLLNAKE-- 71
A +AEA +R L E++ +E + GAE +L+ + +E A+E
Sbjct: 1423 ARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEA 1482
Query: 72 -----QVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVD 126
QV +Q E L + + + + LEEL+ + ER+ ++ +
Sbjct: 1483 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1542
Query: 127 EDTTVTIPSAVYVAQ 141
+ + A+ AQ
Sbjct: 1543 VERARQVQVALETAQ 1557
Score = 27.3 bits (59), Expect = 8.6
Identities = 37/136 (27%), Positives = 62/136 (45%), Gaps = 16/136 (11%)
Query: 4 FRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREI--LTMEKE 61
FR++ E + L +L EA+++R L + +R + AEK L I T K
Sbjct: 1782 FRELAEEAARLRALA----EEAKRQRQLAEEDAARQRAEAERVLAEK-LAAIGEATRLKT 1836
Query: 62 VAQSLLNAKEQVHQGGVELQQLEAGL-----QEAGEEDTRLKASLLQLTR----ELEELK 112
A+ L KE ++ L + EA ++A + ++ L QL + ELE K
Sbjct: 1837 EAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQK 1896
Query: 113 EIEADLERQEKEVDED 128
+ D RQ ++V+E+
Sbjct: 1897 GLVEDTLRQRRQVEEE 1912
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 47.8 bits (112), Expect = 6e-06
Identities = 35/118 (29%), Positives = 65/118 (55%), Gaps = 9/118 (7%)
Query: 20 ANRAEAQQRRLLGRHEQVVERLLETQDG-AEKQLREILTMEKEVAQSLLNAKEQVHQGGV 78
A RA+A+Q L R +Q + +E AE+ LR+ +E+E+ L +E HQ +
Sbjct: 2174 ARRAQAEQAAL--RQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNL 2231
Query: 79 ---ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEV---DEDTT 130
ELQ+L+A EA + ++++ L + ++EEL +++A +E + + + D+D T
Sbjct: 2232 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2289
Score = 40.4 bits (93), Expect = 0.001
Identities = 33/116 (28%), Positives = 60/116 (51%), Gaps = 8/116 (6%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLRE----ILTMEKEVAQSLLNAKEQVHQGG 77
R EA+ R L+ R + +R L+ + KQ+ E + +E A+ A+E + Q
Sbjct: 2273 RIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQR 2332
Query: 78 VELQQLEAGLQEAGEEDTRLK--ASLLQLTREL--EELKEIEADLERQEKEVDEDT 129
+++ +A +E TRLK A LLQ +EL E+ + ++ D E+ +++ E+T
Sbjct: 2333 ALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEET 2388
Score = 35.4 bits (80), Expect = 0.032
Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 12/125 (9%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQ 81
R E ++R + + ERL E + EKQ +++A++ AK Q + ELQ
Sbjct: 1370 RMEEEERLAEQQRAEERERLAEVEAALEKQ--------RQLAEAHAQAKAQAEREAKELQ 1421
Query: 82 QL----EAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTTVTIPSAV 137
Q +EA + + K S+ + ++L + E E + ++ E E + + I +
Sbjct: 1422 QRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEI 1481
Query: 138 YVAQL 142
V +L
Sbjct: 1482 RVVRL 1486
Score = 33.9 bits (76), Expect = 0.092
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 21/127 (16%)
Query: 23 AEAQQRRLLGRHEQVVERLLETQDG------AEKQLREILTMEKE--------VAQSLLN 68
A+ Q RRL EQ+ ++L E G AE+Q + ++ E E ++++
Sbjct: 2366 AQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQAR 2425
Query: 69 AKE-------QVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQ 121
A+E Q + G +L + E QE L+ Q + E L+E A+LER+
Sbjct: 2426 AEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELERE 2485
Query: 122 EKEVDED 128
++++ ++
Sbjct: 2486 KEKLQQE 2492
Score = 33.1 bits (74), Expect = 0.16
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 9/105 (8%)
Query: 26 QQRRLLGRHEQVVERLLE-TQDGAEKQLRE--------ILTMEKEVAQSLLNAKEQVHQG 76
+ RRL R EQ R L+ Q+ A+K+L+ + E+E+ Q+L + + Q
Sbjct: 2047 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2106
Query: 77 GVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQ 121
E + +EA E + + Q R++EE + ++ E Q
Sbjct: 2107 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQ 2151
Score = 32.3 bits (72), Expect = 0.27
Identities = 33/126 (26%), Positives = 54/126 (42%), Gaps = 16/126 (12%)
Query: 12 QGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREI-------LTMEKEVAQ 64
Q + L +AEA+ R R Q +E L + AE++LR+ + + E AQ
Sbjct: 1539 QAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ 1598
Query: 65 SLLNAKEQVHQGGV--ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQE 122
A+ Q + + QLE LQE ++ QL E E + +A+ ER
Sbjct: 1599 RSAEAELQSKRASFAEKTAQLERSLQEE-------HVAVAQLREEAERRAQQQAEAERAR 1651
Query: 123 KEVDED 128
+E + +
Sbjct: 1652 EEAERE 1657
Score = 31.6 bits (70), Expect = 0.46
Identities = 24/95 (25%), Positives = 54/95 (56%), Gaps = 2/95 (2%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQ 81
RAE +R + E++ E+L T+ ++++ + T+E + QS +A E++ + EL+
Sbjct: 2425 RAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDA-ERLREAIAELE 2483
Query: 82 QLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEA 116
+ + LQ+ + +LK+ +Q ++ + L+E +A
Sbjct: 2484 REKEKLQQEAKL-LQLKSEEMQTVQQEQLLQETQA 2517
Score = 31.2 bits (69), Expect = 0.60
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 18/119 (15%)
Query: 24 EAQQRRLL----GRHE-QVVERLLETQDGAEKQLR-------EILTMEKEVAQSLLNAK- 70
EA QRR L +H+ + ERL + + ++ +L + L ++V + +L K
Sbjct: 1900 EAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKA 1959
Query: 71 --EQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDE 127
E+ G EL+ LE G + EDT +L E +++ A+ ER+ +E +E
Sbjct: 1960 SFEKAAAGKAELE-LELGRIRSNAEDTLRSKEQAEL--EAARQRQLAAEEERRRREAEE 2015
Score = 28.5 bits (62), Expect = 3.9
Identities = 34/134 (25%), Positives = 56/134 (41%), Gaps = 15/134 (11%)
Query: 5 RDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQ 64
R IE+ L L A+AQQ R E Q E++ + ++ +E +
Sbjct: 2534 RFIEQEKAKLEQLFQDEVAKAQQLR---------EEQQRQQQQMEQERQRLVASMEEARR 2584
Query: 65 SLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKE 124
A+E V + ELQQLE Q+ +++ L +L +L+ L+E +E
Sbjct: 2585 RQHEAEEGVRRKQEELQQLE---QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEE 2641
Query: 125 VDED---TTVTIPS 135
V T T+P+
Sbjct: 2642 VTASQVAATKTLPN 2655
Score = 28.1 bits (61), Expect = 5.0
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 25/123 (20%)
Query: 29 RLLGRHEQVVERLLETQDGAEKQLREI-------------LTMEKEVAQSLLNAKEQVHQ 75
RL + E+V ++ Q AEKQ E ++E+A+ L + Q+ +
Sbjct: 1670 RLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAE 1729
Query: 76 GGV--------ELQQLEAGLQEAGEEDTRLKASLLQLTRE----LEELKEIEADLERQEK 123
G EL +L A ++ ++ L+ L +L RE ++ +E+EA+L +
Sbjct: 1730 GTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRA 1789
Query: 124 EVD 126
E++
Sbjct: 1790 EME 1792
Score = 27.7 bits (60), Expect = 6.6
Identities = 29/135 (21%), Positives = 54/135 (40%), Gaps = 13/135 (9%)
Query: 20 ANRAEAQQRRLLGRHEQV------VERLLETQDGAEKQLREILTMEKEVAQSLLNAKE-- 71
A +AEA +R L E++ +E + GAE +L+ + +E A+E
Sbjct: 1464 ARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEA 1523
Query: 72 -----QVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVD 126
QV +Q E L + + + + LEEL+ + ER+ ++ +
Sbjct: 1524 ERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAE 1583
Query: 127 EDTTVTIPSAVYVAQ 141
+ + A+ AQ
Sbjct: 1584 VERARQVQVALETAQ 1598
Score = 27.3 bits (59), Expect = 8.6
Identities = 37/136 (27%), Positives = 62/136 (45%), Gaps = 16/136 (11%)
Query: 4 FRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREI--LTMEKE 61
FR++ E + L +L EA+++R L + +R + AEK L I T K
Sbjct: 1823 FRELAEEAARLRALA----EEAKRQRQLAEEDAARQRAEAERVLAEK-LAAIGEATRLKT 1877
Query: 62 VAQSLLNAKEQVHQGGVELQQLEAGL-----QEAGEEDTRLKASLLQLTR----ELEELK 112
A+ L KE ++ L + EA ++A + ++ L QL + ELE K
Sbjct: 1878 EAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQK 1937
Query: 113 EIEADLERQEKEVDED 128
+ D RQ ++V+E+
Sbjct: 1938 GLVEDTLRQRRQVEEE 1953
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 47.0 bits (110), Expect = 1e-05
Identities = 26/73 (35%), Positives = 41/73 (56%)
Query: 49 EKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTREL 108
EK+L+EI ++ + KEQ+ + ++QL+ L+EA EE TR AS +L REL
Sbjct: 1848 EKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQREL 1907
Query: 109 EELKEIEADLERQ 121
++ E L R+
Sbjct: 1908 DDATEANEGLSRE 1920
Score = 37.4 bits (85), Expect = 0.008
Identities = 38/155 (24%), Positives = 71/155 (45%), Gaps = 13/155 (8%)
Query: 1 MAAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREI---LT 57
+ +EE + LL AEA +RL + ++L +T++ +++L ++ L
Sbjct: 1384 LGTIESLEEAKKKLLK-----DAEALSQRLEEK-ALAYDKLEKTKNRLQQELDDLTVDLD 1437
Query: 58 MEKEVAQSLLNAKEQVHQGGVELQQLEAGLQE----AGEEDTRLKASLLQLTRELEELKE 113
+++VA +L +++ Q E + + A E A E + L L R LEE E
Sbjct: 1438 HQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALE 1497
Query: 114 IEADLERQEKEVDEDTTVTIPSAVYVAQLYHQVSK 148
+ + ERQ K++ D + S V + H++ K
Sbjct: 1498 AKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEK 1532
Score = 37.0 bits (84), Expect = 0.011
Identities = 30/108 (27%), Positives = 55/108 (50%), Gaps = 10/108 (9%)
Query: 21 NRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVEL 80
N+AE Q+R L E + L +T D Q +E+ T ++ L A E+ E
Sbjct: 1135 NKAEKQKRDLSEELEALKTELEDTLDTTAAQ-QELRTKREQEVAELKKALEE------ET 1187
Query: 81 QQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDED 128
+ EA +Q+ + R +L +L+ +LE+ K +A+LE+ ++ ++ D
Sbjct: 1188 KNHEAQIQDMRQ---RHATALEELSEQLEQAKRFKANLEKNKQGLETD 1232
Score = 35.8 bits (81), Expect = 0.024
Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 14/117 (11%)
Query: 20 ANRAEAQQRR---LLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSL---LNAKEQV 73
A+ E +Q++ LL + + R E +D AE + RE T +A++L L AKE+
Sbjct: 1443 ASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEF 1502
Query: 74 HQGGVEL----QQLEAGLQEAGEEDTRLKASLLQLTRELEE----LKEIEADLERQE 122
+ +L + L + + G+ L+ S L +++EE L+E+E +L+ E
Sbjct: 1503 ERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATE 1559
Score = 35.4 bits (80), Expect = 0.032
Identities = 34/155 (21%), Positives = 78/155 (50%), Gaps = 9/155 (5%)
Query: 7 IEEVSQGLLSLLGANRAEAQQRRLL-GRHEQVVERLLETQDGAEKQLREILTMEKEVAQS 65
I+++ + +L L N ++++L+ R + +L E ++ A K L +I ++ +
Sbjct: 980 IKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKA-KNLAKIRNKQEVMISD 1038
Query: 66 LLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELK----EIEADLERQ 121
L +E++ + Q+LE ++ E T L+ + +L +++ELK + E +L+
Sbjct: 1039 L---EERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGA 1095
Query: 122 EKEVDEDTTVTIPSAVYVAQLYHQVSKIEWDYECE 156
D++T + V +L Q+++++ D+E E
Sbjct: 1096 LARGDDETLHKNNALKVVRELQAQIAELQEDFESE 1130
Score = 31.6 bits (70), Expect = 0.46
Identities = 23/81 (28%), Positives = 41/81 (50%), Gaps = 3/81 (3%)
Query: 50 KQLREILTMEKEVA---QSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTR 106
K L ++ E+E+ + LL KE+ + EL+++E Q+ EE L L T
Sbjct: 842 KPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETE 901
Query: 107 ELEELKEIEADLERQEKEVDE 127
E +E+ A L +++E++E
Sbjct: 902 LFAEAEEMRARLAAKKQELEE 922
Score = 29.6 bits (65), Expect = 1.7
Identities = 24/106 (22%), Positives = 50/106 (47%), Gaps = 26/106 (24%)
Query: 38 VERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRL 97
+E L+ ++D K + E+ ++ + Q QV + +L++LE LQ + RL
Sbjct: 1513 MEDLMSSKDDVGKNVHELEKSKRALEQ-------QVEEMRTQLEELEDELQATEDAKLRL 1565
Query: 98 KASL----LQLTRELE---------------ELKEIEADLERQEKE 124
+ ++ Q R+L+ +++E+EA+LE + K+
Sbjct: 1566 EVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQ 1611
Score = 27.3 bits (59), Expect = 8.6
Identities = 23/87 (26%), Positives = 40/87 (45%), Gaps = 7/87 (8%)
Query: 41 LLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKAS 100
L E + +L + T+ +E + + + +LQ + LQ E+TR K +
Sbjct: 1278 LAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQ----EETRQKLN 1333
Query: 101 LLQLTRELEELKEIEADLERQEKEVDE 127
L R+LEE K L+ Q++E +E
Sbjct: 1334 LSSRIRQLEEEKN---SLQEQQEEEEE 1357
>gi|194353964 coiled-coil domain containing 157 [Homo sapiens]
Length = 752
Score = 45.1 bits (105), Expect = 4e-05
Identities = 33/100 (33%), Positives = 54/100 (54%), Gaps = 6/100 (6%)
Query: 16 SLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQ 75
SL RA +Q L + + + L+ + ++ E L E+E Q L A++++ Q
Sbjct: 446 SLQAKQRALLKQLDSLDQEREELRGSLDEAEAQRARVEEQLQSEREQGQCQLRAQQELLQ 505
Query: 76 GGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIE 115
LQ+ + GL++A T L+ ++L+L RELEELKE E
Sbjct: 506 S---LQREKQGLEQA---TTDLRLTILELERELEELKERE 539
Score = 31.6 bits (70), Expect = 0.46
Identities = 52/199 (26%), Positives = 80/199 (40%), Gaps = 32/199 (16%)
Query: 1 MAAFRDIEEVSQGLLSLLGAN--RAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTM 58
+ F+ + + S GL L A R A+QR+ L R + VE L + AE Q +
Sbjct: 251 LGQFQQLVQDSMGLRPLPAATVGRWAAEQRKDLTRLSKHVEALRAQLEEAEGQKDGLRKQ 310
Query: 59 EKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADL 118
++ Q+L +EQ G +Q E Q E + + QL E +LK A L
Sbjct: 311 AGKLEQAL--KQEQ----GARRRQAEEDEQCLSEWEHDKQ----QLLTETSDLKTKMATL 360
Query: 119 ERQEKEVDEDTTVTIPSAV--------------YVAQLYHQVSKIEWDYECEPGMVKGIH 164
ER+ K+ E T A V QL QV ++E + G ++G
Sbjct: 361 ERELKQQRESTQAVEAKAQQLQEEGERRAAAERQVQQLEEQVQQLEAQVQLLVGRLEG-- 418
Query: 165 HGPSVAQPIHLDSTQLSRK 183
Q + ST+L ++
Sbjct: 419 ----AGQQVCWASTELDKE 433
Score = 28.1 bits (61), Expect = 5.0
Identities = 26/103 (25%), Positives = 46/103 (44%), Gaps = 8/103 (7%)
Query: 20 ANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVE 79
A A+AQQ + G ER ++ E+Q++++ + + L A +QV E
Sbjct: 373 AVEAKAQQLQEEGERRAAAERQVQQ---LEEQVQQLEAQVQLLVGRLEGAGQQVCWASTE 429
Query: 80 LQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQE 122
L + +A + L+A L ++L+ L D ER+E
Sbjct: 430 LDKEKARVDSMVRHQESLQAKQRALLKQLDSL-----DQEREE 467
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 43.5 bits (101), Expect = 1e-04
Identities = 28/101 (27%), Positives = 52/101 (51%), Gaps = 4/101 (3%)
Query: 31 LGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAK----EQVHQGGVELQQLEAG 86
LG Q V+ L + E++L+ I + KE Q LL + + + E +++ A
Sbjct: 261 LGLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAK 320
Query: 87 LQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDE 127
L + +L+ L+ LT+ +EEL+E +L++ E+E+ E
Sbjct: 321 LANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQE 361
Score = 33.5 bits (75), Expect = 0.12
Identities = 26/112 (23%), Positives = 56/112 (50%), Gaps = 4/112 (3%)
Query: 21 NRAEAQQRRL--LGRHEQVVERLLETQDGAE-KQLREILTMEKEVAQSLLNAKEQ-VHQG 76
N E ++ RL L E+ + E ++ +LR+ L K A L++ ++ + Q
Sbjct: 202 NLLEQERERLKKLLEQEKAYQARKEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQL 261
Query: 77 GVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDED 128
G++ Q+++ Q+ EE+ +LKA + + ++L ++E D E + ++
Sbjct: 262 GLQSQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQE 313
Score = 30.8 bits (68), Expect = 0.78
Identities = 32/132 (24%), Positives = 61/132 (46%), Gaps = 23/132 (17%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAE---------KQLREILTMEKEVAQSLLNAKEQ 72
+ E L+ E + +R+LE + E ++LR+ L E+ ++ L E+
Sbjct: 368 KGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEK 427
Query: 73 VHQGGVELQQLEAGLQEAGEEDTRLKASL---LQLTREL-----------EELKEIEADL 118
+ + EL++LE ++ E T+L +L LT++L +EL+ E+ L
Sbjct: 428 LQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRL 487
Query: 119 ERQEKEVDEDTT 130
E+ E + +D T
Sbjct: 488 EKAELSLKDDLT 499
Score = 30.8 bits (68), Expect = 0.78
Identities = 21/105 (20%), Positives = 43/105 (40%), Gaps = 6/105 (5%)
Query: 5 RDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQ 64
+ +EE+ + + E + RH ++ + L+ + KE
Sbjct: 679 QQLEEIKHQIAKNKAIEKGEVVSQEAELRHR------FRLEEAKSRDLKAEVQALKEKIH 732
Query: 65 SLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELE 109
L+N ++Q+ Q V+ L+ E ++ + +L LT+ELE
Sbjct: 733 ELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKELE 777
Score = 29.6 bits (65), Expect = 1.7
Identities = 27/134 (20%), Positives = 63/134 (47%), Gaps = 8/134 (5%)
Query: 24 EAQQRRLLGRHEQVVERLLETQDGAEKQLR-------EILTMEKEVAQSLLNAKEQVHQG 76
E + R HE++ +L Q+ +QLR + + +E ++L A+E++ +
Sbjct: 304 EHKASRFSQEHEEMNAKLAN-QESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQEL 362
Query: 77 GVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTTVTIPSA 136
++ + E G E L+ +L++ + EE+ + E+ K++ E+ +
Sbjct: 363 RDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELR 422
Query: 137 VYVAQLYHQVSKIE 150
+ V +L ++S++E
Sbjct: 423 LEVEKLQKRMSELE 436
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 43.1 bits (100), Expect = 2e-04
Identities = 24/73 (32%), Positives = 40/73 (54%)
Query: 49 EKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTREL 108
EK+L+++L + ++ K+Q + L+QL+ L+EA EE R AS +L REL
Sbjct: 1841 EKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQREL 1900
Query: 109 EELKEIEADLERQ 121
E+ E + R+
Sbjct: 1901 EDATETADAMNRE 1913
Score = 37.0 bits (84), Expect = 0.011
Identities = 31/102 (30%), Positives = 55/102 (53%), Gaps = 15/102 (14%)
Query: 26 QQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEA 85
Q+ ++ + E++V ++ E Q AE +L E+ T++ ++ L +EQ+ Q E
Sbjct: 843 QEEEMMAKEEELV-KVREKQLAAENRLTEMETLQSQLMAEKLQLQEQL--------QAET 893
Query: 86 GLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDE 127
L EE L+A +LT + +EL+EI DLE + +E +E
Sbjct: 894 ELCAEAEE---LRA---RLTAKKQELEEICHDLEARVEEEEE 929
Score = 37.0 bits (84), Expect = 0.011
Identities = 27/110 (24%), Positives = 55/110 (50%), Gaps = 14/110 (12%)
Query: 21 NRAEAQQRRLLGRHEQVVERLLETQD--GAEKQLREILTMEKEVAQSLLNAKEQVHQGGV 78
N+AE Q+R L E + L +T D A+++LR E + + L + + H+
Sbjct: 1128 NKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHE--A 1185
Query: 79 ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDED 128
++Q++ +A EE L +LE+ K ++A+LE+ ++ ++ +
Sbjct: 1186 QIQEMRQKHSQAVEE----------LAEQLEQTKRVKANLEKAKQTLENE 1225
Score = 34.7 bits (78), Expect = 0.054
Identities = 39/144 (27%), Positives = 67/144 (46%), Gaps = 14/144 (9%)
Query: 21 NRAEA--QQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGV 78
NR EA Q R+L + + + L +T+ E EIL KE + L + + ++ Q
Sbjct: 1632 NRDEAIKQLRKLQAQMKDCMRELDDTRASRE----EILAQAKENEKKLKSMEAEMIQLQE 1687
Query: 79 ELQQLEAGLQEAGEEDTRLKASLLQLTRE----LEELKEIEADLERQEKEVDED--TTVT 132
EL E ++A +E L + + + LEE + +EA + + E+E++E+ T
Sbjct: 1688 ELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTEL 1747
Query: 133 IPSAVYVAQLYHQVSKIEWDYECE 156
I + A L Q+ +I D E
Sbjct: 1748 INDRLKKANL--QIDQINTDLNLE 1769
Score = 34.3 bits (77), Expect = 0.070
Identities = 39/145 (26%), Positives = 66/145 (45%), Gaps = 12/145 (8%)
Query: 5 RDIEEVSQGLLSLLGA-NRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVA 63
+D+E +SQ + A ++ E + RL +Q ++ LL D + + +K+
Sbjct: 1392 KDLEGLSQRHEEKVAAYDKLEKTKTRL----QQELDDLLVDLDHQRQSACNLEKKQKKFD 1447
Query: 64 QSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEK 123
Q L K + E + EA EA E++T+ L L R LEE E +A+LER K
Sbjct: 1448 QLLAEEKTISAKYAEERDRAEA---EAREKETKA----LSLARALEEAMEQKAELERLNK 1500
Query: 124 EVDEDTTVTIPSAVYVAQLYHQVSK 148
+ + + S V + H++ K
Sbjct: 1501 QFRTEMEDLMSSKDDVGKSVHELEK 1525
Score = 33.1 bits (74), Expect = 0.16
Identities = 27/104 (25%), Positives = 53/104 (50%), Gaps = 8/104 (7%)
Query: 29 RLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQ 88
+L +HE ++ L E EKQ +E+ +++ + +Q+ + ++ +L+ L
Sbjct: 1020 KLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLA 1079
Query: 89 EAGEEDTRLKASLLQLTRELEE----LKEIEADLERQEKEVDED 128
+ EE L+A+L ++ E + LK+I +LE Q E+ ED
Sbjct: 1080 KKEEE---LQAALARVEEEAAQKNMALKKIR-ELESQISELQED 1119
Score = 32.7 bits (73), Expect = 0.20
Identities = 29/124 (23%), Positives = 57/124 (45%), Gaps = 26/124 (20%)
Query: 20 ANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVE 79
A +A+ RL + +E L+ ++D K + E+ ++ + Q QV + +
Sbjct: 1488 AMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQ-------QVEEMKTQ 1540
Query: 80 LQQLEAGLQEAGEEDTRLKASL----LQLTRELE---------------ELKEIEADLER 120
L++LE LQ + RL+ +L Q R+L+ +++E+EA+LE
Sbjct: 1541 LEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELED 1600
Query: 121 QEKE 124
+ K+
Sbjct: 1601 ERKQ 1604
Score = 32.3 bits (72), Expect = 0.27
Identities = 28/154 (18%), Positives = 74/154 (48%), Gaps = 7/154 (4%)
Query: 7 IEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSL 66
++++ + + L N A++++LL +++ E + EK + + ++ + +
Sbjct: 973 LKKLEEEQIILEDQNCKLAKEKKLL--EDRIAEFTTNLTEEEEKS-KSLAKLKNKHEAMI 1029
Query: 67 LNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELK----EIEADLERQE 122
+ +E++ + + Q+LE ++ + T L + +L ++ ELK + E +L+
Sbjct: 1030 TDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAAL 1089
Query: 123 KEVDEDTTVTIPSAVYVAQLYHQVSKIEWDYECE 156
V+E+ + + +L Q+S+++ D E E
Sbjct: 1090 ARVEEEAAQKNMALKKIRELESQISELQEDLESE 1123
Score = 30.0 bits (66), Expect = 1.3
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 21/114 (18%)
Query: 23 AEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQ 82
AE + RL + +++ E + + E+ E+E Q L K+++ Q +Q+
Sbjct: 899 AEELRARLTAKKQELEEICHDLEARVEE--------EEERCQHLQAEKKKMQQN---IQE 947
Query: 83 LEAGLQEAGEEDTRLKASLLQLTRE--LEELKEIEADLERQ------EKEVDED 128
LE L+E EE R K L ++T E L++L+E + LE Q EK++ ED
Sbjct: 948 LEEQLEE--EESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLED 999
Score = 29.6 bits (65), Expect = 1.7
Identities = 32/141 (22%), Positives = 66/141 (46%), Gaps = 9/141 (6%)
Query: 21 NRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVEL 80
+RAEA+ R + + L E + + +L + + + L+++K+ V + EL
Sbjct: 1465 DRAEAEAREKETKALSLARALEEAME-QKAELERLNKQFRTEMEDLMSSKDDVGKSVHEL 1523
Query: 81 QQLEAGLQEAGEEDTRLKASLLQLTRELEELKE----IEADLERQEKEVDEDTT-VTIPS 135
++ + L++ EE +K L +L EL+ ++ +E +L+ + + + D S
Sbjct: 1524 EKSKRALEQQVEE---MKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQS 1580
Query: 136 AVYVAQLYHQVSKIEWDYECE 156
QL QV ++E + E E
Sbjct: 1581 EEKKKQLVRQVREMEAELEDE 1601
Score = 28.9 bits (63), Expect = 3.0
Identities = 24/98 (24%), Positives = 47/98 (47%), Gaps = 5/98 (5%)
Query: 34 HEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVEL-QQLEAGLQEAGE 92
HE ++ + + A ++L E L K V +L AK+ + EL +++ LQ G+
Sbjct: 1183 HEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGD 1242
Query: 93 EDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTT 130
+ + K ++ +L+EL+ + ER E+ + T
Sbjct: 1243 SEHKRK----KVEAQLQELQVKFNEGERVRTELADKVT 1276
Score = 28.9 bits (63), Expect = 3.0
Identities = 19/90 (21%), Positives = 42/90 (46%)
Query: 40 RLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKA 99
++ + ++ + + +E K+V ++ K+ + Q E + E +A + TRLK
Sbjct: 1815 KIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQ 1874
Query: 100 SLLQLTRELEELKEIEADLERQEKEVDEDT 129
QL EE + A + ++E+++ T
Sbjct: 1875 LKRQLEEAEEEAQRANASRRKLQRELEDAT 1904
Score = 28.5 bits (62), Expect = 3.9
Identities = 23/107 (21%), Positives = 53/107 (49%), Gaps = 6/107 (5%)
Query: 24 EAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQ-- 81
E +R+L G + +++ E Q + ++ E+E+ +L +E+ Q + L+
Sbjct: 1047 EKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKI 1106
Query: 82 -QLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDE 127
+LE+ + E E+ +AS + ++ +L E +LE + E+++
Sbjct: 1107 RELESQISELQEDLESERASRNKAEKQKRDLGE---ELEALKTELED 1150
Score = 27.3 bits (59), Expect = 8.6
Identities = 24/123 (19%), Positives = 50/123 (40%), Gaps = 14/123 (11%)
Query: 20 ANRAEAQQRRLLGRHEQVVERLLE--------------TQDGAEKQLREILTMEKEVAQS 65
A EAQ + + +H Q VE L E + E + E+ K + Q
Sbjct: 1180 AKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQG 1239
Query: 66 LLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEV 125
+++ + + +LQ+L+ E T L + +L EL+ + + + + + ++
Sbjct: 1240 KGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKL 1299
Query: 126 DED 128
+D
Sbjct: 1300 TKD 1302
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 42.7 bits (99), Expect = 2e-04
Identities = 34/122 (27%), Positives = 59/122 (48%), Gaps = 6/122 (4%)
Query: 8 EEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERL---LETQDGAEKQLREILTMEKEVAQ 64
EE + +LG + + R L+ E V RL L+ + ++QL E L +E
Sbjct: 730 EENDEFRRRILGLEQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEG 789
Query: 65 SLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKE 124
SL AK + L++ + GL G+E L +L + ++ E L+ +A+LE Q++
Sbjct: 790 SLAAAKRALE---ARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAELEEQKRL 846
Query: 125 VD 126
+D
Sbjct: 847 LD 848
Score = 34.7 bits (78), Expect = 0.054
Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 5/107 (4%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQ 81
+ A R L E+ E Q +K ++ ++E+ Q + +E + G +++
Sbjct: 549 KMSALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEEMEEELGEKIE 608
Query: 82 QLEAGLQEAGEE--DTR-LKASLLQLTRELEELKEIEADLERQEKEV 125
L+ L++A DTR ++ +L R EELKE++A ERQ +EV
Sbjct: 609 VLQRELEQARASAGDTRQVEVLKKELLRTQEELKELQA--ERQSQEV 653
Score = 30.0 bits (66), Expect = 1.3
Identities = 29/131 (22%), Positives = 59/131 (45%), Gaps = 10/131 (7%)
Query: 7 IEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLE----------TQDGAEKQLREIL 56
+E++ ++ G+ +A A Q L + E++ +L E +Q G E+QL E
Sbjct: 341 LEKMQPLVMVSSGSTKAVAGQGELTRKVEELQRKLDEEVKKRQKLEPSQVGLERQLEEKT 400
Query: 57 TMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEA 116
+ + L K + Q ELQ ++ L + + L+ +++L +L+ ++ E
Sbjct: 401 EECSRLQELLERRKGEAQQSNKELQNMKRLLDQGEDLRHGLETQVMELQNKLKHVQGPEP 460
Query: 117 DLERQEKEVDE 127
E K++ E
Sbjct: 461 AKEVLLKDLLE 471
Score = 29.3 bits (64), Expect = 2.3
Identities = 30/136 (22%), Positives = 61/136 (44%), Gaps = 13/136 (9%)
Query: 6 DIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQS 65
D+ Q LL L + + LG +V++R LE + R++ ++KE+ ++
Sbjct: 581 DLRATKQELLQL---RMEKEEMEEELGEKIEVLQRELEQARASAGDTRQVEVLKKELLRT 637
Query: 66 LLNAKE-QVHQGGVEL------QQLE---AGLQEAGEEDTRLKASLLQLTRELEELKEIE 115
KE Q + E+ ++LE A L+ + L+ LQL + L++L++
Sbjct: 638 QEELKELQAERQSQEVAGRHRDRELEKQLAVLRVEADRGRELEEQNLQLQKTLQQLRQDC 697
Query: 116 ADLERQEKEVDEDTTV 131
+ + + + + TV
Sbjct: 698 EEASKAKMVAEAEATV 713
Score = 27.3 bits (59), Expect = 8.6
Identities = 29/126 (23%), Positives = 57/126 (45%), Gaps = 18/126 (14%)
Query: 14 LLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLRE----------ILTMEKEVA 63
L +L GA + E R +Q VE + + +QLR +L E++
Sbjct: 497 LTALKGALKEEVASR------DQEVEHVRQQYQRDTEQLRRSMQDATQDHAVLEAERQKM 550
Query: 64 QSLLNA-KEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEEL-KEIEADLERQ 121
+L+ + ++ + E ++ Q+ E+ K LLQL E EE+ +E+ +E
Sbjct: 551 SALVRGLQRELEETSEETGHWQSMFQKNKEDLRATKQELLQLRMEKEEMEEELGEKIEVL 610
Query: 122 EKEVDE 127
++E+++
Sbjct: 611 QRELEQ 616
>gi|5803145 ralA binding protein 1 [Homo sapiens]
Length = 655
Score = 42.0 bits (97), Expect = 3e-04
Identities = 22/96 (22%), Positives = 51/96 (53%)
Query: 31 LGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEA 90
+ +E+V+ LL ++ + E+L ME+ + + + + KE++ + E+ ++++ Q
Sbjct: 472 MNENEEVINILLAQENEILTEQEELLAMEQFLRRQIASEKEEIERLRAEIAEIQSRQQHG 531
Query: 91 GEEDTRLKASLLQLTRELEELKEIEADLERQEKEVD 126
E + + + EEL+ I DL+RQ +E++
Sbjct: 532 RSETEEYSSESESESEDEEELQIILEDLQRQNEELE 567
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 42.0 bits (97), Expect = 3e-04
Identities = 35/127 (27%), Positives = 67/127 (52%), Gaps = 6/127 (4%)
Query: 12 QGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKE 71
+GL+ + A AE + R L E+ L + E++++E++ + SL + K+
Sbjct: 1145 EGLVVQMEARIAELEDR--LESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQKD 1202
Query: 72 QVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTTV 131
Q+ + L+ ++ ++EA EE RL++S +L RELEE ++ L+ Q + +D +
Sbjct: 1203 QL---SLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRL 1259
Query: 132 -TIPSAV 137
+PS V
Sbjct: 1260 KKLPSKV 1266
Score = 32.7 bits (73), Expect = 0.20
Identities = 29/128 (22%), Positives = 58/128 (45%), Gaps = 4/128 (3%)
Query: 2 AAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKE 61
A R + V + + +L AQ V+ LLE + ++ E+ +
Sbjct: 573 ATKRKVNLVFEKIQTLKSRAAGSAQGNNQACNSTSEVKDLLEQKSKLTIEVAELQRQLQL 632
Query: 62 VAQSLLNAKEQVHQGGVELQQLEAGLQEAGEEDT----RLKASLLQLTRELEELKEIEAD 117
++ N KE+ + L++L + E EE++ RL+ S +L + LEEL +++ +
Sbjct: 633 EVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKME 692
Query: 118 LERQEKEV 125
E+ + E+
Sbjct: 693 REQHQTEI 700
Score = 32.7 bits (73), Expect = 0.20
Identities = 27/128 (21%), Positives = 59/128 (46%), Gaps = 11/128 (8%)
Query: 24 EAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQL 83
+ + +L GR E++ R+ + Q R+I ++ + A+ AKE + + E++QL
Sbjct: 828 QEENEKLQGRSEELERRVAQLQ-------RQIEDLKGDEAK----AKETLKKYEGEIRQL 876
Query: 84 EAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDTTVTIPSAVYVAQLY 143
E L A +E+ ++ L ELE + + +++K++ E + +L
Sbjct: 877 EEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLK 936
Query: 144 HQVSKIEW 151
+++ W
Sbjct: 937 NEMENERW 944
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 42.0 bits (97), Expect = 3e-04
Identities = 41/142 (28%), Positives = 73/142 (51%), Gaps = 12/142 (8%)
Query: 3 AFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLL--ETQDGAEKQLREILTMEK 60
A ++ SQ L + N A+A + R + E ++L +TQ A + L + L ++K
Sbjct: 2044 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKK 2103
Query: 61 EVAQSLLNAKEQVHQGGVELQ-QLEAGLQEAGEEDTRLKASLLQLTRE---LEE-LKEIE 115
E+ + + K Q+ Q +L+ +LE ++ +E ++ L L RE LEE + EI+
Sbjct: 2104 ELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQ 2163
Query: 116 ADLERQEKEVDE-----DTTVT 132
L +++KEV + D+TVT
Sbjct: 2164 VTLNKKDKEVQQLQENLDSTVT 2185
Score = 34.3 bits (77), Expect = 0.070
Identities = 19/76 (25%), Positives = 42/76 (55%), Gaps = 4/76 (5%)
Query: 75 QGGVELQQLEAGLQEAGEEDTRLK----ASLLQLTRELEELKEIEADLERQEKEVDEDTT 130
QGG + Q++A L+E E L+ ++ +LT++ EE+ +++ + +Q E++ T
Sbjct: 1299 QGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKT 1358
Query: 131 VTIPSAVYVAQLYHQV 146
V+ + V+ L ++
Sbjct: 1359 VSHEAEVHAESLQQKL 1374
Score = 33.5 bits (75), Expect = 0.12
Identities = 32/132 (24%), Positives = 58/132 (43%), Gaps = 8/132 (6%)
Query: 1 MAAFRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEK 60
+ A D ++ L +L+ R+ + Q + L Q R + A + L E
Sbjct: 2971 LMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQYQ---RQASPETSASPDGSQNLVYET 3027
Query: 61 EVAQSLLN-AKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLE 119
E+ ++ LN + +++HQ + +QQL + + EE L L ++ L E ++ DL
Sbjct: 3028 ELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLL 3087
Query: 120 RQ----EKEVDE 127
EK+V E
Sbjct: 3088 NHCAVLEKQVQE 3099
Score = 32.7 bits (73), Expect = 0.20
Identities = 40/187 (21%), Positives = 82/187 (43%), Gaps = 32/187 (17%)
Query: 24 EAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQL 83
++QQ++ LLE Q K+L +E + A E + + LQ+
Sbjct: 2548 DSQQKQ-----------LLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEE 2596
Query: 84 EAGLQEAGEEDTRLKASLLQLTRELEELKE------IEADLERQEKEVDEDTTVTIPSAV 137
+ Q+ +E LK S+ QLTR++ L+E A L+ +E+EV + + S
Sbjct: 2597 K---QDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQK 2653
Query: 138 YVAQLYHQVSKIEWDYECEPGMV--------KGIHHGPSVAQPIHLDSTQLSRKFISDYL 189
+A+L ++ ++ + + G + K +HH + + + T+ + + +++
Sbjct: 2654 RIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMR----NETETAEERVAELA 2709
Query: 190 WSLVDTE 196
LV+ E
Sbjct: 2710 RDLVEME 2716
Score = 31.2 bits (69), Expect = 0.60
Identities = 21/106 (19%), Positives = 55/106 (51%), Gaps = 5/106 (4%)
Query: 63 AQSLLNAKEQVHQGGVELQQLEAGLQEAGEE----DTRLKASLLQLTRELEELKEIEADL 118
++ + +EQ+++ G+E++ L+ EA +L++S LQ+ LE L+E++ L
Sbjct: 1336 SEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIA-GLEHLRELQPKL 1394
Query: 119 ERQEKEVDEDTTVTIPSAVYVAQLYHQVSKIEWDYECEPGMVKGIH 164
+ +K + + + +++ ++KI+ + + ++K +H
Sbjct: 1395 DELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALH 1440
Score = 27.3 bits (59), Expect = 8.6
Identities = 21/79 (26%), Positives = 40/79 (50%), Gaps = 11/79 (13%)
Query: 42 LETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGE-EDTRL--- 97
+E + ++ ++E L +++ L K+ + Q V+LQQ + LQE + D ++
Sbjct: 40 MEFNNTTQEDVQERLAYAEQLVVEL---KDIIRQKDVQLQQKDEALQEERKAADNKIKKL 96
Query: 98 ----KASLLQLTRELEELK 112
KA L L + +EE+K
Sbjct: 97 KLHAKAKLTSLNKYIEEMK 115
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 40.4 bits (93), Expect = 0.001
Identities = 33/144 (22%), Positives = 66/144 (45%), Gaps = 5/144 (3%)
Query: 10 VSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNA 69
+S+ LL L A A++R + ++ E L Q ++ RE+ T +++ ++LL
Sbjct: 1744 LSRALLELRAEMTAAAEERIISATSQK--EAHLNVQQIVDRHTRELKTQVEDLNENLLKL 1801
Query: 70 KEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVD--- 126
KE + L L + E + + + ++ RE EE+ + +L+RQ K +
Sbjct: 1802 KEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGL 1861
Query: 127 EDTTVTIPSAVYVAQLYHQVSKIE 150
+ +T + +L +V K+E
Sbjct: 1862 QGKPLTDNKQSLIEELQRKVKKLE 1885
Score = 38.5 bits (88), Expect = 0.004
Identities = 31/145 (21%), Positives = 65/145 (44%), Gaps = 19/145 (13%)
Query: 24 EAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSL-------------LNAK 70
+ ++ L+ ++ +VE + + EKQ E+L+ME EV + + + A
Sbjct: 890 QVNEKSLIRQYTTLVELERQLRKENEKQKNELLSMEAEVCEKIGCLQRFKEMAIFKIAAL 949
Query: 71 EQVHQGGVELQQLEAGLQEAGEEDTRLK------ASLLQLTRELEELKEIEADLERQEKE 124
++V V L +LE ++ E + + L+Q T LE L+ L+ Q +
Sbjct: 950 QKVVDNSVSLSELELANKQYNELTAKYRDILQKDNMLVQRTSNLEHLECENISLKEQVES 1009
Query: 125 VDEDTTVTIPSAVYVAQLYHQVSKI 149
++++ +T + Q + Q +K+
Sbjct: 1010 INKELEITKEKLHTIEQAWEQETKL 1034
Score = 35.4 bits (80), Expect = 0.032
Identities = 35/130 (26%), Positives = 59/130 (45%), Gaps = 19/130 (14%)
Query: 36 QVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVEL--------------- 80
+V E E Q+ R ++ K AQ + A E+V + G E
Sbjct: 36 EVNELKSEKQENVIHLFRITQSLMKMKAQEVELALEEVEKAGEEQAKFENQLKTKVMKLE 95
Query: 81 QQLEAGLQEAGEEDTR-LKASLLQLTRELEELKEIEADLERQEKEVDEDTTVTIPSAVYV 139
+LE Q AG DTR L+ + QL ++LE+ + +LE EKE++++ V A+
Sbjct: 96 NELEMAQQSAGGRDTRFLRNEICQLEKQLEQK---DRELEDMEKELEKEKKVNEQLALRN 152
Query: 140 AQLYHQVSKI 149
+ ++ SK+
Sbjct: 153 EEAENENSKL 162
Score = 30.0 bits (66), Expect = 1.3
Identities = 26/139 (18%), Positives = 66/139 (47%), Gaps = 16/139 (11%)
Query: 6 DIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLL----------ETQDGAEKQLREI 55
DI + +Q + L + ++ + + ++ + +E+ + ET+ G +++L+ +
Sbjct: 2285 DIAKKNQSITDLKQLVKEATEREQKVNKYNEDLEQQIKILKHVPEGAETEQGLKRELQVL 2344
Query: 56 LT----MEKEVAQSLLNAKEQVHQGGVE--LQQLEAGLQEAGEEDTRLKASLLQLTRELE 109
++KE A+ + + Q G E + + ++ + +T+LK S L+ E
Sbjct: 2345 RLANHQLDKEKAELIHQIEANKDQSGAESTIPDADQLKEKIKDLETQLKMSDLEKQHLKE 2404
Query: 110 ELKEIEADLERQEKEVDED 128
E+K+++ +LE + E+
Sbjct: 2405 EIKKLKKELENFDPSFFEE 2423
Score = 28.9 bits (63), Expect = 3.0
Identities = 38/147 (25%), Positives = 70/147 (47%), Gaps = 16/147 (10%)
Query: 29 RLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKE--QVHQGGVELQQLEA- 85
+++ +E++ + L + D AEK L + K + +LN K Q+ + G LQ E+
Sbjct: 2201 KIIAENERLRKELKKETDAAEK-----LRIAKNNLE-ILNEKMTVQLEETGKRLQFAESR 2254
Query: 86 GLQEAGEEDTRLKASLLQLTRELE-ELKEIEADLERQEKEVDEDTTVTIPSAVYVAQLYH 144
G Q G + K+ + +TR E +LKE+E D+ ++ + + D + A Q
Sbjct: 2255 GPQLEGADSKSWKS--IVVTRMYETKLKELETDIAKKNQSI-TDLKQLVKEATEREQ--- 2308
Query: 145 QVSKIEWDYECEPGMVKGIHHGPSVAQ 171
+V+K D E + ++K + G Q
Sbjct: 2309 KVNKYNEDLEQQIKILKHVPEGAETEQ 2335
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 40.4 bits (93), Expect = 0.001
Identities = 40/122 (32%), Positives = 64/122 (52%), Gaps = 13/122 (10%)
Query: 4 FRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVA 63
+R+ EE+ Q LL R E ++RR Q ER +D +++ ++L E+E
Sbjct: 990 YREEEELQQEEEQLL---REEREKRR-----RQEWERQYRKKDELQQEEEQLLREEREKR 1041
Query: 64 QSLLNAKEQVHQGGVELQQLEAGLQEAGEE-DTRLKASLLQLTRELEELKEIEADLERQE 122
+ L +E+ ++ ELQQ E L GEE +TR + L + R+ EEL++ E L R+E
Sbjct: 1042 R--LQERERQYREEEELQQEEEQL--LGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097
Query: 123 KE 124
E
Sbjct: 1098 PE 1099
Score = 37.7 bits (86), Expect = 0.006
Identities = 39/141 (27%), Positives = 65/141 (46%), Gaps = 21/141 (14%)
Query: 4 FRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGA-------------EK 50
+R+ EE+ Q LLG R E ++R+ L R + E L + ++ E+
Sbjct: 1050 YREEEELQQEEEQLLGEER-ETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERER 1108
Query: 51 QLREILTMEKEVAQSLLNAKEQVHQGGVELQQLEAGLQEAGEE-------DTRLKASLLQ 103
Q RE +++E Q L +E+ + +E Q E + EE + R + L +
Sbjct: 1109 QCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELER 1168
Query: 104 LTRELEELKEIEADLERQEKE 124
RE EEL++ E L R+E+E
Sbjct: 1169 QYREEEELQQEEEQLLREEQE 1189
Score = 34.3 bits (77), Expect = 0.070
Identities = 31/109 (28%), Positives = 53/109 (48%), Gaps = 5/109 (4%)
Query: 17 LLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQG 76
LL E Q+ R Q ER ++ +++ ++L E+E + +E+ ++
Sbjct: 905 LLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRR--QERERQYRK 962
Query: 77 GVELQQLEAGLQEAGEE-DTRLKASLLQLTRELEELKEIEADLERQEKE 124
+LQQ E L GEE + R + + RE EEL++ E L R+E+E
Sbjct: 963 DKKLQQKEEQL--LGEEPEKRRRQEREKKYREEEELQQEEEQLLREERE 1009
Score = 33.9 bits (76), Expect = 0.092
Identities = 35/121 (28%), Positives = 59/121 (48%), Gaps = 11/121 (9%)
Query: 4 FRDIEEVSQGLLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVA 63
+R +E+ Q LL R E ++RRL R ER ++ +++ ++L E+E
Sbjct: 1020 YRKKDELQQEEEQLL---REEREKRRLQER-----ERQYREEEELQQEEEQLLGEERETR 1071
Query: 64 QSLLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEK 123
+ E+ ++ ELQQ E L E + R + + RE EEL++ E L R+E+
Sbjct: 1072 RR--QELERQYRKEEELQQEEEQLLRE-EPEKRRRQERERQCREEEELQQEEEQLLREER 1128
Query: 124 E 124
E
Sbjct: 1129 E 1129
Score = 32.7 bits (73), Expect = 0.20
Identities = 38/131 (29%), Positives = 65/131 (49%), Gaps = 18/131 (13%)
Query: 4 FRDIEEVSQG-LLSLLGANRAEAQQRRLLGRHEQVVERLLETQDGAEKQLRE-ILTMEKE 61
F D E++ + LL L R E QQ+R R Q +R+ + ++ E + RE +L E+E
Sbjct: 204 FPDEEQLRRRELLELRRKGREEKQQQR---RERQ--DRVFQEEEEKEWRKRETVLRKEEE 258
Query: 62 VAQS--------LLNAKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKE 113
Q L +EQ+ + +E Q+L QE ++ RL+ QL R+ EE +
Sbjct: 259 KLQEEEPQRQRELQEEEEQLRK--LERQELRRERQEEEQQQQRLRRE-QQLRRKQEEERR 315
Query: 114 IEADLERQEKE 124
+ + R+++E
Sbjct: 316 EQQEERREQQE 326
Score = 32.7 bits (73), Expect = 0.20
Identities = 40/147 (27%), Positives = 67/147 (45%), Gaps = 20/147 (13%)
Query: 17 LLGANRAEAQQRRLLGRHEQVVERL-------LETQDGAEKQLREILTMEKEVAQSLLNA 69
LL QQR + E++ +RL LE ++ E++L+ E+E Q LL +
Sbjct: 578 LLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKRE-EPEEERRQQLLKS 636
Query: 70 KEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKEVDEDT 129
+EQ + QQL QE E+ RLK + LE+ + E + ER+E+E+ E+
Sbjct: 637 EEQEER---RQQQLRREQQERREQ--RLKRE--EEEERLEQRLKREHEEERREQELAEEE 689
Query: 130 TVTIPSAVYVAQLYHQVSKIEWDYECE 156
++ ++ K +W E E
Sbjct: 690 QEQARE-----RIKSRIPKWQWQLESE 711
Score = 31.6 bits (70), Expect = 0.46
Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 31/130 (23%)
Query: 24 EAQQRRLLGRHEQVVE-RLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVH--QGGVEL 80
E ++R+L Q E R L ++ E++ R+ EKE+ L +EQ+ + +L
Sbjct: 792 EQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKEL--QFLEEEEQLQRRERAQQL 849
Query: 81 QQLEAGLQE-------------------AGEEDTRLKASLL-------QLTRELEELKEI 114
Q+ E GLQE EE R + +L QL +E + L+E
Sbjct: 850 QEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEE 909
Query: 115 EADLERQEKE 124
E +L+R+E+E
Sbjct: 910 EEELQREERE 919
Score = 28.9 bits (63), Expect = 3.0
Identities = 28/108 (25%), Positives = 55/108 (50%), Gaps = 12/108 (11%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEKQLREILTMEKEVAQSLLNAKEQVHQGGVELQ 81
R + ++R+ L +Q+ + LE + E+QLR+ E Q L +E+ ++ +E +
Sbjct: 1701 RRQERERKFLQEEQQLRRQELERKFREEEQLRQ------ETEQEQLRRQER-YRKILEEE 1753
Query: 82 QLEAGLQE----AGEEDTRLK-ASLLQLTRELEELKEIEADLERQEKE 124
QL +E E D + + L+ RE ++L+ E+D + +E+E
Sbjct: 1754 QLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEE 1801
Score = 27.7 bits (60), Expect = 6.6
Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 4/106 (3%)
Query: 22 RAEAQQRRLLGRHEQVVERLLETQDGAEK---QLREILTMEKEVAQSLLNAKEQVHQGGV 78
RA+ Q G E R + Q +K QL E + + +EQ+ +
Sbjct: 845 RAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQ 904
Query: 79 ELQQLEAGLQEAGEEDTRLKASLLQLTRELEELKEIEADLERQEKE 124
LQ+ E LQ E R + Q RE E+L++ E L R+E+E
Sbjct: 905 LLQEEEEELQREEREKRRRQEQERQY-REEEQLQQEEEQLLREERE 949
>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
sapiens]
Length = 638
Score = 40.4 bits (93), Expect = 0.001
Identities = 37/128 (28%), Positives = 65/128 (50%), Gaps = 25/128 (19%)
Query: 21 NRAEAQQRRLLGRHE------QVVERLLETQDGAEKQLR-EILTMEKEV------AQSLL 67
N+ E + R ++ + E QV +R LE G QL +++++EKE + LL
Sbjct: 89 NKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLL 148
Query: 68 N-------AKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQ----LTRELEELKEIEA 116
A +QV + +++ QLE L+E +E LK SL + L++++E+L ++
Sbjct: 149 EYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDL-NVKC 207
Query: 117 DLERQEKE 124
L +EKE
Sbjct: 208 QLLEKEKE 215
>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
sapiens]
Length = 725
Score = 40.4 bits (93), Expect = 0.001
Identities = 37/128 (28%), Positives = 65/128 (50%), Gaps = 25/128 (19%)
Query: 21 NRAEAQQRRLLGRHE------QVVERLLETQDGAEKQLR-EILTMEKEV------AQSLL 67
N+ E + R ++ + E QV +R LE G QL +++++EKE + LL
Sbjct: 176 NKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLL 235
Query: 68 N-------AKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQ----LTRELEELKEIEA 116
A +QV + +++ QLE L+E +E LK SL + L++++E+L ++
Sbjct: 236 EYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDL-NVKC 294
Query: 117 DLERQEKE 124
L +EKE
Sbjct: 295 QLLEKEKE 302
Score = 29.6 bits (65), Expect = 1.7
Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 3/72 (4%)
Query: 43 ETQDGAEKQLREILTMEKEVAQSLLNAKEQ---VHQGGVELQQLEAGLQEAGEEDTRLKA 99
E++ ++K +++ +EKE+ L Q + EL+++EA L A E T L A
Sbjct: 73 ESKKESQKNDKDLKILEKEIRVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSA 132
Query: 100 SLLQLTRELEEL 111
+ L ++L EL
Sbjct: 133 NNATLEKQLIEL 144
>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
sapiens]
Length = 709
Score = 40.4 bits (93), Expect = 0.001
Identities = 37/128 (28%), Positives = 65/128 (50%), Gaps = 25/128 (19%)
Query: 21 NRAEAQQRRLLGRHE------QVVERLLETQDGAEKQLR-EILTMEKEV------AQSLL 67
N+ E + R ++ + E QV +R LE G QL +++++EKE + LL
Sbjct: 160 NKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLL 219
Query: 68 N-------AKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQ----LTRELEELKEIEA 116
A +QV + +++ QLE L+E +E LK SL + L++++E+L ++
Sbjct: 220 EYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDL-NVKC 278
Query: 117 DLERQEKE 124
L +EKE
Sbjct: 279 QLLEKEKE 286
>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
sapiens]
Length = 724
Score = 40.4 bits (93), Expect = 0.001
Identities = 37/128 (28%), Positives = 65/128 (50%), Gaps = 25/128 (19%)
Query: 21 NRAEAQQRRLLGRHE------QVVERLLETQDGAEKQLR-EILTMEKEV------AQSLL 67
N+ E + R ++ + E QV +R LE G QL +++++EKE + LL
Sbjct: 175 NKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLL 234
Query: 68 N-------AKEQVHQGGVELQQLEAGLQEAGEEDTRLKASLLQ----LTRELEELKEIEA 116
A +QV + +++ QLE L+E +E LK SL + L++++E+L ++
Sbjct: 235 EYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDL-NVKC 293
Query: 117 DLERQEKE 124
L +EKE
Sbjct: 294 QLLEKEKE 301
Score = 28.1 bits (61), Expect = 5.0
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
Query: 48 AEKQLREILTMEKEVAQSLLNAKEQ---VHQGGVELQQLEAGLQEAGEEDTRLKASLLQL 104
++K +++ +EKE+ L Q + EL+++EA L A E T L A+ L
Sbjct: 77 SQKNDKDLKILEKEIRVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNATL 136
Query: 105 TRELEEL 111
++L EL
Sbjct: 137 EKQLIEL 143
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,887,670
Number of Sequences: 37866
Number of extensions: 299858
Number of successful extensions: 3888
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 196
Number of HSP's successfully gapped in prelim test: 434
Number of HSP's that attempted gapping in prelim test: 2189
Number of HSP's gapped (non-prelim): 1887
length of query: 197
length of database: 18,247,518
effective HSP length: 97
effective length of query: 100
effective length of database: 14,574,516
effective search space: 1457451600
effective search space used: 1457451600
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.