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Search of human proteins with 31795544
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31795544 origin recognition complex, subunit 1 [Homo
sapiens]
(861 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31795544 origin recognition complex, subunit 1 [Homo sapiens] 1709 0.0
gi|4502703 cell division cycle 6 protein [Homo sapiens] 170 5e-42
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 60 7e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 50 7e-06
gi|32454748 origin recognition complex subunit 4 [Homo sapiens] 44 6e-04
gi|32454746 origin recognition complex subunit 4 [Homo sapiens] 44 6e-04
gi|32454750 origin recognition complex subunit 4 [Homo sapiens] 44 6e-04
gi|4507241 structure specific recognition protein 1 [Homo sapiens] 44 8e-04
gi|82775371 coiled-coil domain containing 93 [Homo sapiens] 44 8e-04
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 44 8e-04
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 41 0.004
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 41 0.004
gi|109255230 centrosomal protein 170kDa isoform beta [Homo sapiens] 41 0.004
gi|109255228 centrosomal protein 170kDa isoform alpha [Homo sapi... 41 0.004
gi|109255232 centrosomal protein 170kDa isoform gamma [Homo sapi... 41 0.004
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 40 0.012
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 39 0.016
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 39 0.016
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 39 0.027
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 39 0.027
gi|11321634 CD2-associated protein [Homo sapiens] 38 0.035
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 38 0.035
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 38 0.035
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 38 0.046
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap... 38 0.046
gi|239758038 PREDICTED: mucin 3A, cell surface associated, parti... 37 0.079
gi|122937243 dual specificity phosphatase 27 [Homo sapiens] 36 0.13
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 36 0.13
gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens] 36 0.13
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 36 0.13
>gi|31795544 origin recognition complex, subunit 1 [Homo sapiens]
Length = 861
Score = 1709 bits (4425), Expect = 0.0
Identities = 861/861 (100%), Positives = 861/861 (100%)
Query: 1 MAHYPTRLKTRKTYSWVGRPLLDRKLHYQTYREMCVKTEGCSTEIHIQIGQFVLIEGDDD 60
MAHYPTRLKTRKTYSWVGRPLLDRKLHYQTYREMCVKTEGCSTEIHIQIGQFVLIEGDDD
Sbjct: 1 MAHYPTRLKTRKTYSWVGRPLLDRKLHYQTYREMCVKTEGCSTEIHIQIGQFVLIEGDDD 60
Query: 61 ENPYVAKLLELFEDDSDPPPKKRARVQWFVRFCEVPACKRHLLGRKPGAQEIFWYDYPAC 120
ENPYVAKLLELFEDDSDPPPKKRARVQWFVRFCEVPACKRHLLGRKPGAQEIFWYDYPAC
Sbjct: 61 ENPYVAKLLELFEDDSDPPPKKRARVQWFVRFCEVPACKRHLLGRKPGAQEIFWYDYPAC 120
Query: 121 DSNINAETIIGLVRVIPLAPKDVVPTNLKNEKTLFVKLSWNEKKFRPLSSELFAELNKPQ 180
DSNINAETIIGLVRVIPLAPKDVVPTNLKNEKTLFVKLSWNEKKFRPLSSELFAELNKPQ
Sbjct: 121 DSNINAETIIGLVRVIPLAPKDVVPTNLKNEKTLFVKLSWNEKKFRPLSSELFAELNKPQ 180
Query: 181 ESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLELG 240
ESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLELG
Sbjct: 181 ESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLELG 240
Query: 241 NLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEKTRETG 300
NLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEKTRETG
Sbjct: 241 NLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEKTRETG 300
Query: 301 LSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKK 360
LSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKK
Sbjct: 301 LSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKK 360
Query: 361 RDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSS 420
RDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSS
Sbjct: 361 RDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSS 420
Query: 421 SDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLA 480
SDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLA
Sbjct: 421 SDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLA 480
Query: 481 AQEPASVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGK 540
AQEPASVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGK
Sbjct: 481 AQEPASVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGK 540
Query: 541 TATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKATANHAAEL 600
TATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKATANHAAEL
Sbjct: 541 TATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKATANHAAEL 600
Query: 601 LAKQFCTRGSPQETTVLLVDELDLLWTHKQDIMYNLFDWPTHKEARLVVLAIANTMDLPE 660
LAKQFCTRGSPQETTVLLVDELDLLWTHKQDIMYNLFDWPTHKEARLVVLAIANTMDLPE
Sbjct: 601 LAKQFCTRGSPQETTVLLVDELDLLWTHKQDIMYNLFDWPTHKEARLVVLAIANTMDLPE 660
Query: 661 RIMMNRVSSRLGLTRMCFQPYTYSQLQQILRSRLKHLKAFEDDAIQLVARKVAALSGDAR 720
RIMMNRVSSRLGLTRMCFQPYTYSQLQQILRSRLKHLKAFEDDAIQLVARKVAALSGDAR
Sbjct: 661 RIMMNRVSSRLGLTRMCFQPYTYSQLQQILRSRLKHLKAFEDDAIQLVARKVAALSGDAR 720
Query: 721 RCLDICRRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRA 780
RCLDICRRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRA
Sbjct: 721 RCLDICRRATEICEFSQQKPDSPGLVTIAHSMEAVDEMFSSSYITAIKNSSVLEQSFLRA 780
Query: 781 ILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRND 840
ILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRND
Sbjct: 781 ILAEFRRSGLEEATFQQIYSQHVALCRMEGLPYPTMSETMAVCSHLGSCRLLLVEPSRND 840
Query: 841 LLLRVRLNVSQDDVLYALKDE 861
LLLRVRLNVSQDDVLYALKDE
Sbjct: 841 LLLRVRLNVSQDDVLYALKDE 861
>gi|4502703 cell division cycle 6 protein [Homo sapiens]
Length = 560
Score = 170 bits (431), Expect = 5e-42
Identities = 129/471 (27%), Positives = 228/471 (48%), Gaps = 52/471 (11%)
Query: 422 DEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLAA 481
D + P R + + SS++ S T ++ + C L
Sbjct: 99 DNQLTIKSPSKRELAKVHQNKILSSVRKSQEITTNSEQRCPLKKESACVR-------LFK 151
Query: 482 QEPASVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGKT 541
QE + ++A+L L+ +AVP+ LP RE+E I NF+ + G +Y+SG PGTGKT
Sbjct: 152 QE-GTCYQQAKLVLN-TAVPDRLPAREREMDVIRNFLREHICGKKAGSLYLSGAPGTGKT 209
Query: 542 ATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKATANHAAEL- 600
A + +++ L++ ++ F+ I +N M L V+ I Q++ ++ + ++
Sbjct: 210 ACLSRILQDLKK-----ELKGFKTIMLNCMSLRTAQAVFPAIAQEICQEEVSRPAGKDMM 264
Query: 601 --LAKQFCTRGSPQETTVLLVDELDLLWTHKQDIMYNLFDWPTHKEARLVVLAIANTMDL 658
L K P VL++DE+D L + QD++Y LF+WP + LV++ IANT+DL
Sbjct: 265 RKLEKHMTAEKGPM--IVLVLDEMDQLDSKGQDVLYTLFEWPWLSNSHLVLIGIANTLDL 322
Query: 659 PERIMMNRVSSRLGLTRMC------FQPYTYSQLQQILRSRLKHL---KAFEDDAIQLVA 709
+RI+ RL C F PYT +Q+ IL+ RL + + ++ A+Q A
Sbjct: 323 TDRIL-----PRLQAREKCKPQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAVQFCA 377
Query: 710 RKVAALSGDARRCLDICRRATEICEFSQQK------------------PDSPGLVTIAHS 751
RKV+A+SGD R+ LD+CRRA EI E + P GL+ I+
Sbjct: 378 RKVSAVSGDVRKALDVCRRAIEIVESDVKSQTILKPLSECKSPSEPLIPKRVGLIHISQV 437
Query: 752 MEAVDEMFSSSYITAIKNSSVLEQSFL-RAILAEFRRSGLEEATFQQIYSQHVALCRMEG 810
+ VD + ++S L+Q L +++ R+ ++E T ++Y + +CR +
Sbjct: 438 ISEVDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEVTLGKLYEAYSKVCRKQQ 497
Query: 811 LPYPTMSETMAVCSHLGSCRLLLVEPSRNDLLLRVRLNVSQDDVLYALKDE 861
+ SE +++ L + +L ++ ++ L +V + + ++ +ALKD+
Sbjct: 498 VAAVDQSECLSLSGLLEARGILGLKRNKETRLTKVFFKIEEKEIEHALKDK 548
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 60.5 bits (145), Expect = 7e-09
Identities = 74/351 (21%), Positives = 142/351 (40%), Gaps = 22/351 (6%)
Query: 162 EKKFRPLSSELFAELNKPQESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKS 221
E++ + +E A K +S K + A++KS E V +++ A +
Sbjct: 498 EEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 557
Query: 222 RQTPTHPLTPRARKRLELGNLGNPQMSQQTSCASLDSPGRIK-----RKVAFSEITSPSK 276
++P +P + + +P+ ++ + SP K + E SP++
Sbjct: 558 AKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE 617
Query: 277 RSQPDKLQTLSPA-LKAPEKTRETGLSYTEDDKKA-SPEHRIILRTRIAAS--KTIDIRE 332
P K + SPA +K+PEK + + +KA SPE A S K
Sbjct: 618 AKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSP 677
Query: 333 ERTLTPISGGQRS-----SVVPSVILKPENIKKRDAKEAKAQNEATSTPHRIRRKSSVLT 387
E+ +P+ +S S V PE K +EAK+ +A S P + K+
Sbjct: 678 EKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKS-PVKEEAKTPEKA 736
Query: 388 MNRIRQQLRFLGNSKSDQEEKEI-LPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRS- 445
+ ++++ + +KS ++ K + + + E + +E + P +A V ++S
Sbjct: 737 KSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSP 796
Query: 446 -SLKSSLHTLTKVPKKSLKPRTPRCAAP---QIRSRSLAAQEPASVLEEAR 492
KS L K P+K + P+ +P + + + + +EP EE +
Sbjct: 797 EKAKSPLKEDAKAPEKEI-PKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEK 846
Score = 48.5 bits (114), Expect = 3e-05
Identities = 58/266 (21%), Positives = 110/266 (41%), Gaps = 46/266 (17%)
Query: 243 GNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPA-LKAPEKTRETGL 301
G + ++ SP + + E SP++ P+K + SPA +K+PEK +
Sbjct: 496 GGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAK---- 551
Query: 302 SYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKKR 361
S +++ K+ PE +K+ + E ++ P+ + PE K
Sbjct: 552 SPAKEEAKSPPE-----------AKSPEKEEAKS-------------PAEVKSPEKAKSP 587
Query: 362 DAKEAKAQNEATS-----TPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEI 416
+EAK+ EA S +P + KS + ++++ + KS ++ K P E
Sbjct: 588 AKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKS--PTKEE 645
Query: 417 SDS----SSDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKP-----RTP 467
+ S S E+E + P ++P KS + K P+K+ P ++P
Sbjct: 646 AKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSP 705
Query: 468 RCAAPQIRSRSLAAQEPAS-VLEEAR 492
A ++ + + ++ S V EEA+
Sbjct: 706 EKAKSPVKEEAKSPEKAKSPVKEEAK 731
Score = 43.1 bits (100), Expect = 0.001
Identities = 64/302 (21%), Positives = 118/302 (39%), Gaps = 46/302 (15%)
Query: 181 ESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLELG 240
+S K + PV+ ++KS E +P + AK E S K TP K
Sbjct: 689 KSPEKAKSPVKEEAKSPEKAK-SPVKEEAKSPEKAKSPVKEEAK-----TPEKAK----- 737
Query: 241 NLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEKTRETG 300
+P + S SP + K ++ SP ++ P K + SPA K PEK +
Sbjct: 738 ---SPVKEEAKSPEKAKSPEKAKT----LDVKSPEAKT-PAKEEARSPADKFPEKAK--- 786
Query: 301 LSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKK 360
S +++ K+ + + L+ A + ++E +P+ + KP+ +K
Sbjct: 787 -SPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEE----------KPQEVKV 835
Query: 361 RDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSS 420
++ + + +A +TP +K S + + K +++++ + + S
Sbjct: 836 KEPPKKAEEEKAPATPKTEEKKDS----KKEEAPKKEAPKPKVEEKKEPAVEKPKESKVE 891
Query: 421 SDEEEA----STPPLPRRAPRTVSRNLRSSLKSSLHTLTKVP-----KKSLKPRTPRCAA 471
+ +EEA P + AP V + K K P K+ KP + AA
Sbjct: 892 AKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAA 951
Query: 472 PQ 473
P+
Sbjct: 952 PE 953
Score = 32.0 bits (71), Expect = 2.5
Identities = 48/251 (19%), Positives = 96/251 (38%), Gaps = 31/251 (12%)
Query: 185 KCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLELGNLGN 244
K + PV+ + KS E +P + AK E + ++P K E+
Sbjct: 784 KAKSPVKEEVKSPEKAK-SPLKEDAKAPEKEIPKKEEVKSPVK----EEEKPQEVKVKEP 838
Query: 245 PQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEKTRETGLSYT 304
P+ +++ + +P ++K + E + +P + PA++ P++++
Sbjct: 839 PKKAEEEKAPA--TPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEE 896
Query: 305 EDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIK----- 359
+DKK P ++ + +E+ + + PS KP K
Sbjct: 897 AEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPS---KPAEKKEAAPE 953
Query: 360 KRDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDS 419
K+D KE KA+ + K T+++ + K+++ EK S
Sbjct: 954 KKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSK------PKAEKAEK----------S 997
Query: 420 SSDEEEASTPP 430
SS +++ S PP
Sbjct: 998 SSTDQKDSKPP 1008
Score = 30.8 bits (68), Expect = 5.6
Identities = 59/260 (22%), Positives = 105/260 (40%), Gaps = 32/260 (12%)
Query: 61 ENPYVAKLLELFEDDSDPPPKKRARVQWFVRFCEVPACKRHLLGRKPGAQEIFWYDYPAC 120
++P AK L++ ++ P K+ AR PA K + P +E+ P
Sbjct: 751 KSPEKAKTLDVKSPEAKTPAKEEARS---------PADKFPEKAKSPVKEEV---KSPEK 798
Query: 121 DSNINAETIIGLVRVIPLAPKDVVPTNLKNE-KTLFVKLSWNEKKFR----PLSSELFAE 175
+ E + IP K+ V + +K E K VK+ KK P + + +
Sbjct: 799 AKSPLKEDAKAPEKEIP--KKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEK 856
Query: 176 LNKPQESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARK 235
+ +E A K + P + E P E ++E++ ++ ++ P A
Sbjct: 857 KDSKKEEAPKKEAPKPKVEEKKEPAVEKPKE---SKVEAKKEEAEDKKKVPTP-EKEAPA 912
Query: 236 RLELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQ--PDKLQTLSPALKAP 293
++E+ P+ ++T A + P K K E + P+++ + P+K T K P
Sbjct: 913 KVEVKEDAKPK--EKTEVAKKE-PDDAKAK----EPSKPAEKKEAAPEKKDTKEEKAKKP 965
Query: 294 EKTRETGLSYTEDDKKASPE 313
E+ +T EDDK S E
Sbjct: 966 EEKPKTEAKAKEDDKTLSKE 985
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 50.4 bits (119), Expect = 7e-06
Identities = 82/347 (23%), Positives = 135/347 (38%), Gaps = 53/347 (15%)
Query: 174 AELNKPQESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRA 233
+E + +S AK + P+R +S+S SP ++ R S+S +P PRA
Sbjct: 1557 SESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPR------RSRSGSSPEVKDKPRA 1610
Query: 234 RKRLELGNLGNPQMS-------QQTSCASLDSPGRIKRKVAFSEITS----PSK------ 276
R + G+ +P+ + S + S GR S S P K
Sbjct: 1611 APRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARR 1670
Query: 277 --RSQPD-KLQTLSP-----ALKAPEKTRETGLSYTEDDKKASPEHRIILRTRIAASKTI 328
RS P+ K ++ +P + +PE TR+ LS +SPE R R S ++
Sbjct: 1671 GSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSV 1730
Query: 329 DIREERTLTPISGGQRSSVVP----------SVILKPENIKKRDAKEAKAQNEATSTPHR 378
E + S +RS+ P S KP +++ ++++ E T T R
Sbjct: 1731 SSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQR---SRSRSRREKTRTTRR 1787
Query: 379 IRRKSSVLTMNRIRQ----QLRFLGNSKSDQEEKEILPAAEISDSSSDEE---EASTPPL 431
R S + +R RQ + R + PA + S +S + TPP
Sbjct: 1788 RDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPT 1847
Query: 432 PRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRS 478
R+ R+ SR + K S + + + RTP + + RSR+
Sbjct: 1848 SRK--RSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRT 1892
Score = 47.8 bits (112), Expect = 4e-05
Identities = 72/317 (22%), Positives = 123/317 (38%), Gaps = 29/317 (9%)
Query: 191 RAKSKSAESPS-WTPAEHVAKRIESRHSASKSRQTPTH-PLTPRARKRLELGNLGNPQMS 248
R +S+S SP+ W KR SR S + R++ + PL R R R + +
Sbjct: 1849 RKRSRSRTSPAPW-------KRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSR 1901
Query: 249 QQTSCASLDSPGR---IKRKVAFSEITSPSKRSQPDKLQTLS--------PALKAPEKTR 297
+TS S R + R+ + S ++R + T P + ++R
Sbjct: 1902 SRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSR 1961
Query: 298 ETGLSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPEN 357
++ + SP R R+R S R +P++ + S V +
Sbjct: 1962 TPPVTRRRSRSRTSPITR--RRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSR 2019
Query: 358 IKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAE-- 415
+ A ++++ P + R S L + R R + R ++ + PA
Sbjct: 2020 SRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRR-RSRSRTPRTARGKRSLTRSPPAIRRR 2078
Query: 416 -ISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQI 474
S SSSD ++TPP R + SR +L SS + P S P RC +P +
Sbjct: 2079 SASGSSSDRSRSATPPATRN--HSGSRTPPVALNSSRMSCFSRPSMSPTP-LDRCRSPGM 2135
Query: 475 RSRSLAAQEPASVLEEA 491
+++ P SVL++A
Sbjct: 2136 LEPLGSSRTPMSVLQQA 2152
Score = 40.8 bits (94), Expect = 0.005
Identities = 72/343 (20%), Positives = 126/343 (36%), Gaps = 56/343 (16%)
Query: 191 RAKSKSAESPSWTPAEHVAKRIESR-------HSASKSRQTPTHPLTP------------ 231
R +S+S + P W+ + + +R SR HS S + + + TP
Sbjct: 531 RGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPA 590
Query: 232 --RARKRLELGNLGNPQMSQQTSCASLDSPGRIKRKVAF-----SEITSPSKRSQPDKLQ 284
R+R R + + + +P R + + S SP++RS + +
Sbjct: 591 RRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSR 650
Query: 285 TLSPALKAPEKT---RETGLSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISG 341
T + ++ +T R S T + R R + S+T R+ + +
Sbjct: 651 TPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRR 710
Query: 342 GQRSSVVPSVILKPENIKKRDAKEAKAQNEATS-----------TPHRIRRKSSVLTMNR 390
G+ S P + + +R K +Q + S + R R SS + +
Sbjct: 711 GRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAK 770
Query: 391 IRQQLR--FLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPL---------PRRAPRTV 439
R LR G+S +++ + P S SS + ++ TPP P++ +T
Sbjct: 771 SRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTP 830
Query: 440 SRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQ 482
SR SS SS H K PR +PQ +S+ Q
Sbjct: 831 SRQSHSS--SSPHPKV---KSGTPPRQGSITSPQANEQSVTPQ 868
Score = 37.7 bits (86), Expect = 0.046
Identities = 86/379 (22%), Positives = 125/379 (32%), Gaps = 59/379 (15%)
Query: 166 RPLSSELFAELNKPQESAAKCQKPVRAKSKSAESP-----SWTPAEHVAKRIE------- 213
R S E + + P+ + P R +S+S SP S TP+ H
Sbjct: 1412 RTPSRERSSSASSPEMKDGLPRTPSR-RSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIP 1470
Query: 214 -----SRHSASKSRQTPTHPLTPRARKRL----ELGNLG-NPQMSQQTSCASLDSP---- 259
R S + P TPR R R EL N PQ + S +S+D
Sbjct: 1471 RTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVAR 1530
Query: 260 ---GRIKRKVAFSEI-----TSPSKRSQPDKLQTLSPALKAPEKTRETGLSYTEDDKKAS 311
G+ R + E+ SP +RS+ D + P + R S E D K+
Sbjct: 1531 TPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR 1590
Query: 312 PEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKKRDAKEAKAQNE 371
R R+R +S + + R G SS P P + +R + ++
Sbjct: 1591 LSPR---RSRSGSSPEVK-DKPRAAPRAQSGSDSSPEPKA-PAPRALPRRSRSGSSSKGR 1645
Query: 372 ATS------------------TPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPA 413
S T R R S R S + K L
Sbjct: 1646 GPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSR 1705
Query: 414 AEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQ 473
S SSS E + TPP RR+P S +SS + ++ K + R +P
Sbjct: 1706 RSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRT-KTTSRRGRSPS 1764
Query: 474 IRSRSLAAQEPASVLEEAR 492
+ R L S E+ R
Sbjct: 1765 PKPRGLQRSRSRSRREKTR 1783
Score = 35.0 bits (79), Expect = 0.30
Identities = 54/227 (23%), Positives = 86/227 (37%), Gaps = 22/227 (9%)
Query: 163 KKFRPLSSELFAELNKPQESAAKCQKPVRAKSKSAESPSWTPA--EHVAKRIESRHSASK 220
K+ R SS + + S++ S S S P E KR+ S A K
Sbjct: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPK 2587
Query: 221 SRQTPTHPL--TPRARKRLELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRS 278
P TP RKR + + S +S +S S + S +S S S
Sbjct: 2588 EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647
Query: 279 QPDKLQTLSPALKAPEKTRETGLSYTEDDKKASPEHRIILRTRIAASKTIDIREERTL-- 336
P SPA P+ L KK P R R+R +R+ R+L
Sbjct: 2648 SP------SPAKPGPQ-----ALPKPASPKKPPPGER---RSRSPRKPIDSLRDSRSLSY 2693
Query: 337 TPISGGQRSSVVPSVILKPENIKKRDAKEAKAQNEATSTPHRIRRKS 383
+P+ +R S PS + + +R ++ + + ++ S H+ RR++
Sbjct: 2694 SPVE-RRRPSPQPSPRDQQSSSSERGSRRGQ-RGDSRSPSHKRRRET 2738
Score = 33.1 bits (74), Expect = 1.1
Identities = 65/312 (20%), Positives = 105/312 (33%), Gaps = 43/312 (13%)
Query: 179 PQESAAKCQKPVRAKSKSAESPSWT---PAEHVAKRIESRHSASKSRQTPTHPLTPRARK 235
P +S ++ S+ ++PS + PA+ + + +SR +
Sbjct: 2414 PSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQ 2473
Query: 236 RLELGNLGNPQMS--QQTSCASLDSPGRIKRKVAFSEITSPSKRS---QPDKLQTLSPAL 290
L G + S S+ +PG V S++ P + QP L L PA
Sbjct: 2474 SLSSGAVATTTSSAGDHNGMLSVPAPG-----VPHSDVGEPPASTGAQQPSALAALQPA- 2527
Query: 291 KAPEKTRETGLSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPS 350
K R + S + +S + + S + D S G V P
Sbjct: 2528 ----KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD----------SEGSSLPVQPE 2573
Query: 351 VILKPENIKKRDAKEAKAQNEATS-TPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKE 409
V LK KEA + TP + +R+SS + + +S S
Sbjct: 2574 VALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSS 2633
Query: 410 ILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRC 469
++ S SSS + P P+ P+ S K P + R+PR
Sbjct: 2634 SSSSSSSSSSSSSSSPSPAKPGPQALPKPASPK-------------KPPPGERRSRSPRK 2680
Query: 470 AAPQIR-SRSLA 480
+R SRSL+
Sbjct: 2681 PIDSLRDSRSLS 2692
Score = 32.7 bits (73), Expect = 1.5
Identities = 60/297 (20%), Positives = 105/297 (35%), Gaps = 39/297 (13%)
Query: 215 RHSASKSRQTPTHPLTPRARKRLELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSP 274
R S+S TP + + R +P+ ++ S + K +P
Sbjct: 175 RESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTP 234
Query: 275 -SKRSQPDKLQTLSPALKAPEKTRETGLSYTEDDKKASPEHRIILRTRIAASKT-IDIRE 332
SKR DK + S + K+R S + D +S R R+R AA+KT
Sbjct: 235 KSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSR--SRSRSAAAKTHTTALA 292
Query: 333 ERTLTPISGGQRSSVVPSVILKPENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNRIR 392
R+ +P SG + P +P + + + S+P+ + K
Sbjct: 293 GRSPSPASGRRGEGDAP--FSEPGTTSTQRPSSPETATKQPSSPYEDKDK---------- 340
Query: 393 QQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSLH 452
D++EK + S S E ++ P P P R+ S +
Sbjct: 341 -----------DKKEK-----SATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATT 384
Query: 453 TLTKVP------KKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPES 503
L++ P + R+P + ++ S + P S + ++ H S+ PES
Sbjct: 385 PLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSP-QPTKVSRHASSSPES 440
Score = 31.2 bits (69), Expect = 4.3
Identities = 83/368 (22%), Positives = 126/368 (34%), Gaps = 79/368 (21%)
Query: 179 PQESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLE 238
PQE A P R K K + P V R ES + +TP PR R
Sbjct: 1172 PQEDATA--SPPRQKDKFSPFP-------VQDRPESSLVFKDTLRTP-----PRERS--- 1214
Query: 239 LGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALK------- 291
G +P+ +Q S S E+ S+ L LS LK
Sbjct: 1215 -GAGSSPETKEQNSALPTSSQDE-----ELMEVVEKSEEPAGQILSHLSSELKEMSTSNF 1268
Query: 292 --APEKTRETGLSYTEDDKKA---------------------SPEHRIILRTRIAASK-- 326
+PE +S T D ++ SPEH+ + + + +
Sbjct: 1269 ESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFG 1328
Query: 327 -TIDIREERTL-TPISGGQRSSVVPSVILKPENIKKRDAKEAKAQNEATSTPHRIRRKSS 384
++ R L T ++ G S V + N + D + S+ H SS
Sbjct: 1329 SPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGH----SSS 1384
Query: 385 VLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLR 444
L+ + + + G S + +L A + S AS+P + PRT SR R
Sbjct: 1385 ELSPDAVEKA----GMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSR 1440
Query: 445 SSLKSSLHTLTKVPKK-SLK---------PRTPRCAAPQIRSRSLAAQEPASVLEEARLR 494
S L + P + SL PRTP + RS ++ EP ++ + R R
Sbjct: 1441 SGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTP----SRGRSECDSSPEPKALPQTPRPR 1496
Query: 495 LHVSAVPE 502
+ PE
Sbjct: 1497 SRSPSSPE 1504
>gi|32454748 origin recognition complex subunit 4 [Homo sapiens]
Length = 436
Score = 43.9 bits (102), Expect = 6e-04
Identities = 44/206 (21%), Positives = 87/206 (42%), Gaps = 19/206 (9%)
Query: 510 EFQDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVN 569
+++ + ++ L + I G G+GKT ++ ++ L + + ++ + +N
Sbjct: 43 QYKHLSELLKRTALHGESNSVLIIGPRGSGKTMLINHALKELMEIEEVSE--NVLQVHLN 100
Query: 570 GMKLTEPHQVYVQI-----LQKLTGQKATANHAAEL------LAKQFCTRGSPQETTVLL 618
G+ +I L+ + G K + A L L K T P + +
Sbjct: 101 GLLQINDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCP---VIFI 157
Query: 619 VDELDLLWTHK-QDIMYNLFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTRM- 676
+DE DL HK Q ++YNLFD + + V+ + +D+ E ++ RV SR ++
Sbjct: 158 LDEFDLFAHHKNQTLLYNLFDISQSAQTPIAVIGLTCRLDILE-LLEKRVKSRFSHRQIH 216
Query: 677 CFQPYTYSQLQQILRSRLKHLKAFED 702
+ + Q +I + +L F D
Sbjct: 217 LMNSFGFPQYVKIFKEQLSLPAEFPD 242
>gi|32454746 origin recognition complex subunit 4 [Homo sapiens]
Length = 436
Score = 43.9 bits (102), Expect = 6e-04
Identities = 44/206 (21%), Positives = 87/206 (42%), Gaps = 19/206 (9%)
Query: 510 EFQDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVN 569
+++ + ++ L + I G G+GKT ++ ++ L + + ++ + +N
Sbjct: 43 QYKHLSELLKRTALHGESNSVLIIGPRGSGKTMLINHALKELMEIEEVSE--NVLQVHLN 100
Query: 570 GMKLTEPHQVYVQI-----LQKLTGQKATANHAAEL------LAKQFCTRGSPQETTVLL 618
G+ +I L+ + G K + A L L K T P + +
Sbjct: 101 GLLQINDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCP---VIFI 157
Query: 619 VDELDLLWTHK-QDIMYNLFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTRM- 676
+DE DL HK Q ++YNLFD + + V+ + +D+ E ++ RV SR ++
Sbjct: 158 LDEFDLFAHHKNQTLLYNLFDISQSAQTPIAVIGLTCRLDILE-LLEKRVKSRFSHRQIH 216
Query: 677 CFQPYTYSQLQQILRSRLKHLKAFED 702
+ + Q +I + +L F D
Sbjct: 217 LMNSFGFPQYVKIFKEQLSLPAEFPD 242
>gi|32454750 origin recognition complex subunit 4 [Homo sapiens]
Length = 436
Score = 43.9 bits (102), Expect = 6e-04
Identities = 44/206 (21%), Positives = 87/206 (42%), Gaps = 19/206 (9%)
Query: 510 EFQDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVN 569
+++ + ++ L + I G G+GKT ++ ++ L + + ++ + +N
Sbjct: 43 QYKHLSELLKRTALHGESNSVLIIGPRGSGKTMLINHALKELMEIEEVSE--NVLQVHLN 100
Query: 570 GMKLTEPHQVYVQI-----LQKLTGQKATANHAAEL------LAKQFCTRGSPQETTVLL 618
G+ +I L+ + G K + A L L K T P + +
Sbjct: 101 GLLQINDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCP---VIFI 157
Query: 619 VDELDLLWTHK-QDIMYNLFDWPTHKEARLVVLAIANTMDLPERIMMNRVSSRLGLTRM- 676
+DE DL HK Q ++YNLFD + + V+ + +D+ E ++ RV SR ++
Sbjct: 158 LDEFDLFAHHKNQTLLYNLFDISQSAQTPIAVIGLTCRLDILE-LLEKRVKSRFSHRQIH 216
Query: 677 CFQPYTYSQLQQILRSRLKHLKAFED 702
+ + Q +I + +L F D
Sbjct: 217 LMNSFGFPQYVKIFKEQLSLPAEFPD 242
>gi|4507241 structure specific recognition protein 1 [Homo sapiens]
Length = 709
Score = 43.5 bits (101), Expect = 8e-04
Identities = 57/231 (24%), Positives = 93/231 (40%), Gaps = 27/231 (11%)
Query: 206 EHVAKRIESRHSASKSRQTPTHPLTPRARKRLELGNLGNPQMSQQTSCASLDSPGRIKRK 265
E VA+ +S SAS S + RK+L+ + + S+ K+
Sbjct: 489 EDVAEEFDSNASASSSSNEGDSDRDEKKRKQLKKAKMAKDRKSR-------------KKP 535
Query: 266 VAFSEITSPSKRSQPDKLQTL-SPALKAPEKTRETGLSYTEDDKKASPEHRIILRTRIAA 324
V + P+ +P L A + K+ G+S T+ KKA + + + +
Sbjct: 536 VEVKKGKDPNAPKRPMSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEE 595
Query: 325 --SKTIDIRE--ERTLTPISGGQRSSVVPSVILKPENIKKRDAKEAKAQNEATSTPHR-I 379
K D R E+ + GG+ S K + KK+ K+ K + E STP R
Sbjct: 596 WDRKAEDARRDYEKAMKEYEGGRGESS------KRDKSKKK--KKVKVKMEKKSTPSRGS 647
Query: 380 RRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPP 430
KSS ++ + F+ + +S E + S+ S +EE ASTPP
Sbjct: 648 SSKSSSRQLSESFKSKEFVSSDESSSGENKSKKKRRRSEDSEEEELASTPP 698
>gi|82775371 coiled-coil domain containing 93 [Homo sapiens]
Length = 631
Score = 43.5 bits (101), Expect = 8e-04
Identities = 57/242 (23%), Positives = 105/242 (43%), Gaps = 32/242 (13%)
Query: 275 SKRSQPDKLQTLSPALKAPEKTRETGLSYTEDDKKASPEHRIILRTRIAASKTIDIREER 334
S++S+ +K + AL A E ++ ED+ +A+ E RI + T EE
Sbjct: 212 SRQSKMEKAEDKKTALPAGLSATEKADAHEEDELRAAEEQRI---QSLMTKMTAMANEES 268
Query: 335 TLTPISGGQRSSVVPSVI--LKPENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNR-I 391
LT S GQ + + I + E +K+ A+ E T RRK V+++N+ I
Sbjct: 269 RLTASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRK--VISLNKQI 326
Query: 392 RQQLRFLGNSKSDQ--------EEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNL 443
Q+ + L ++ E K+ L + D+E+A+ + +A ++ +NL
Sbjct: 327 AQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSILQNL 386
Query: 444 RS------SLKSS--------LHTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLE 489
R+ +LKS +T++ ++ + R AP+ ++L++ EP L
Sbjct: 387 RALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAER--APRGDEKTLSSGEPPGTLT 444
Query: 490 EA 491
A
Sbjct: 445 SA 446
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 43.5 bits (101), Expect = 8e-04
Identities = 74/342 (21%), Positives = 122/342 (35%), Gaps = 43/342 (12%)
Query: 147 NLKNEKTLFVKLSWNEKKFRPLSSELFAELNKPQESAAKCQKPVRAKSKSAESPSWTPAE 206
N+ + F++L E K R + E A + K E K K + S+ S +P
Sbjct: 115 NIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSP-- 172
Query: 207 HVAKRIESRHSASKSRQTP-------THPLTPRARKRLELGNLGNPQMSQQTSCASLDSP 259
+R +SR + + R +P +H +PR R + +P ++ L P
Sbjct: 173 ---RRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTK---SRSPSPAPEKKEKTPELPEP 226
Query: 260 GRIKRKVAFSEITSPSKRSQPDKLQTL-SPALKAPEKT--RETGLSYTEDDKKASPEHRI 316
++ + E TS S + K + + P +PEK +E T ++ + R
Sbjct: 227 SVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRS 286
Query: 317 ILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKKRDAKEAKAQNEATSTP 376
R+R + S T R R+ + +R PS ++R + + P
Sbjct: 287 RTRSR-SPSHTRPRRRHRSRSRSYSPRRR---PSP-------RRRPSPRRRTPPRRMPPP 335
Query: 377 HRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAP 436
R RR S + R R G+S S S SS PP +P
Sbjct: 336 PRHRRSRSPVRRRR-RSSASLSGSSSS-------------SSSSRSRSPPKKPPKRTSSP 381
Query: 437 RTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRS 478
+R L S P + P+T PQ +R+
Sbjct: 382 PRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRT 423
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 41.2 bits (95), Expect = 0.004
Identities = 96/477 (20%), Positives = 168/477 (35%), Gaps = 108/477 (22%)
Query: 149 KNEKTLFVKLSWNEKKFRPLSSELFAELNKPQESAAKCQKPVRAKSKSAESPSWTPAEHV 208
K++ +FVK+ +K + + E K ++S+ + + +SKS+E S
Sbjct: 1787 KDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSK---RSKSSEHKSRKRTSES 1843
Query: 209 AKRIESRHSASKSRQTPTHPLTPRARKRLELGNLGNPQMSQQTSCASLDSPGRIKRKVAF 268
R R S SKS ++ T R+R R R +R+ +
Sbjct: 1844 RSRARKRSSKSKSHRSQT-----RSRSR-----------------------SRRRRRSSR 1875
Query: 269 SEITSPSKRSQPDKLQTLSPALKAPEKTRETGLSYTEDDKKASPEHRIILRTRIAASKTI 328
S S +RS + + SP ++ + R+ S + D++K + A
Sbjct: 1876 SRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKT-----------VRARSRT 1924
Query: 329 DIREERTLTPISGGQRSSVV---PSVILKPENIKKRDAKEAKAQNEATSTPHRIRRKSSV 385
R R+ TP S +RS V S + P + ++ ++ + + TP R R S
Sbjct: 1925 PSRRSRSHTP-SRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPS- 1982
Query: 386 LTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRS 445
R R R + + ++ S S + T PL RR R+ R RS
Sbjct: 1983 ---RRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT-PLRRRFSRSPIRRKRS 2038
Query: 446 SLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPESLP 505
+ S + R+P + L + A +LE A+ +P
Sbjct: 2039 -------------RSSERGRSP---------KRLTDLDKAQLLEIAKANAAAMCAKAGVP 2076
Query: 506 CREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQA-------- 557
+E K+ +GG AT+ E+ +Q AQ+
Sbjct: 2077 LPPNLKPAPPPTIEEKVAKKSGG-------------ATIEELTEKCKQIAQSKEDDDVIV 2123
Query: 558 ---------NDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKATANHAAELLAKQF 605
+ PPF + + KL+EP ++ + + K T + L K+F
Sbjct: 2124 NKPHVSDEEEEEPPFYH---HPFKLSEPKPIFFNL--NIAAAKPTPPKSQVTLTKEF 2175
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 41.2 bits (95), Expect = 0.004
Identities = 96/477 (20%), Positives = 168/477 (35%), Gaps = 108/477 (22%)
Query: 149 KNEKTLFVKLSWNEKKFRPLSSELFAELNKPQESAAKCQKPVRAKSKSAESPSWTPAEHV 208
K++ +FVK+ +K + + E K ++S+ + + +SKS+E S
Sbjct: 1787 KDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSK---RSKSSEHKSRKRTSES 1843
Query: 209 AKRIESRHSASKSRQTPTHPLTPRARKRLELGNLGNPQMSQQTSCASLDSPGRIKRKVAF 268
R R S SKS ++ T R+R R R +R+ +
Sbjct: 1844 RSRARKRSSKSKSHRSQT-----RSRSR-----------------------SRRRRRSSR 1875
Query: 269 SEITSPSKRSQPDKLQTLSPALKAPEKTRETGLSYTEDDKKASPEHRIILRTRIAASKTI 328
S S +RS + + SP ++ + R+ S + D++K + A
Sbjct: 1876 SRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKT-----------VRARSRT 1924
Query: 329 DIREERTLTPISGGQRSSVV---PSVILKPENIKKRDAKEAKAQNEATSTPHRIRRKSSV 385
R R+ TP S +RS V S + P + ++ ++ + + TP R R S
Sbjct: 1925 PSRRSRSHTP-SRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPS- 1982
Query: 386 LTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRS 445
R R R + + ++ S S + T PL RR R+ R RS
Sbjct: 1983 ---RRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRT-PLRRRFSRSPIRRKRS 2038
Query: 446 SLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSAVPESLP 505
+ S + R+P + L + A +LE A+ +P
Sbjct: 2039 -------------RSSERGRSP---------KRLTDLDKAQLLEIAKANAAAMCAKAGVP 2076
Query: 506 CREQEFQDIYNFVESKLLDHTGGCMYISGVPGTGKTATVHEVIRCLQQAAQA-------- 557
+E K+ +GG AT+ E+ +Q AQ+
Sbjct: 2077 LPPNLKPAPPPTIEEKVAKKSGG-------------ATIEELTEKCKQIAQSKEDDDVIV 2123
Query: 558 ---------NDVPPFQYIEVNGMKLTEPHQVYVQILQKLTGQKATANHAAELLAKQF 605
+ PPF + + KL+EP ++ + + K T + L K+F
Sbjct: 2124 NKPHVSDEEEEEPPFYH---HPFKLSEPKPIFFNL--NIAAAKPTPPKSQVTLTKEF 2175
>gi|109255230 centrosomal protein 170kDa isoform beta [Homo sapiens]
Length = 1486
Score = 41.2 bits (95), Expect = 0.004
Identities = 79/346 (22%), Positives = 136/346 (39%), Gaps = 39/346 (11%)
Query: 171 ELFAELNKPQE-----SAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTP 225
E F + ++P E S +K + +++SK ++ ++ + S S RQ
Sbjct: 681 ETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGS 740
Query: 226 THPLTPRARKRLELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSK--------R 277
P +EL N Q S S +L S RI+ + SE P +
Sbjct: 741 FTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER---SESLDPDSSMDTTLILK 797
Query: 278 SQPDKLQTLSPALKAPEKTRE--TGLSYTEDDKKASPEHRIILRTRIAA----SKTIDIR 331
+ L L+ KT E SY D+ SPE + + I+ ++ +
Sbjct: 798 DTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNS-ISPESDVDTASTISLVTGETERKSTQ 856
Query: 332 EERTLTPISGGQRSSVVPSV-ILKPENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNR 390
+ ++ T + + S+ PS + K + R+ E K ++ +T R + V + R
Sbjct: 857 KRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGR 916
Query: 391 IRQQLRFLGNSKSDQEEKEILPAAEISDSSS-DEEEASTPPLPRRAPRTVSRNLRSSLKS 449
IRQ L +D ++ +P + ISD S D+E S P R + ++ S L+
Sbjct: 917 IRQPSVDL----TDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEG 972
Query: 450 SLHTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEP--ASVLEEARL 493
S T +K +P + +S +L P S+L ARL
Sbjct: 973 SKVTKSKT--------SPVVSGSSSKSTTLPRPRPTRTSLLRRARL 1010
>gi|109255228 centrosomal protein 170kDa isoform alpha [Homo sapiens]
Length = 1584
Score = 41.2 bits (95), Expect = 0.004
Identities = 79/346 (22%), Positives = 136/346 (39%), Gaps = 39/346 (11%)
Query: 171 ELFAELNKPQE-----SAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTP 225
E F + ++P E S +K + +++SK ++ ++ + S S RQ
Sbjct: 779 ETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGS 838
Query: 226 THPLTPRARKRLELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSK--------R 277
P +EL N Q S S +L S RI+ + SE P +
Sbjct: 839 FTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER---SESLDPDSSMDTTLILK 895
Query: 278 SQPDKLQTLSPALKAPEKTRE--TGLSYTEDDKKASPEHRIILRTRIAA----SKTIDIR 331
+ L L+ KT E SY D+ SPE + + I+ ++ +
Sbjct: 896 DTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNS-ISPESDVDTASTISLVTGETERKSTQ 954
Query: 332 EERTLTPISGGQRSSVVPSV-ILKPENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNR 390
+ ++ T + + S+ PS + K + R+ E K ++ +T R + V + R
Sbjct: 955 KRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGR 1014
Query: 391 IRQQLRFLGNSKSDQEEKEILPAAEISDSSS-DEEEASTPPLPRRAPRTVSRNLRSSLKS 449
IRQ L +D ++ +P + ISD S D+E S P R + ++ S L+
Sbjct: 1015 IRQPSVDL----TDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEG 1070
Query: 450 SLHTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEP--ASVLEEARL 493
S T +K +P + +S +L P S+L ARL
Sbjct: 1071 SKVTKSKT--------SPVVSGSSSKSTTLPRPRPTRTSLLRRARL 1108
>gi|109255232 centrosomal protein 170kDa isoform gamma [Homo sapiens]
Length = 1460
Score = 41.2 bits (95), Expect = 0.004
Identities = 79/346 (22%), Positives = 136/346 (39%), Gaps = 39/346 (11%)
Query: 171 ELFAELNKPQE-----SAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTP 225
E F + ++P E S +K + +++SK ++ ++ + S S RQ
Sbjct: 681 ETFKQESQPPEKNSGHSTSKGDRVAQSESKRRKAEEILKSQTPKGGDKKESSKSLVRQGS 740
Query: 226 THPLTPRARKRLELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSK--------R 277
P +EL N Q S S +L S RI+ + SE P +
Sbjct: 741 FTIEKPSPNIPIELIPHINKQTSSTPSSLALTSASRIRER---SESLDPDSSMDTTLILK 797
Query: 278 SQPDKLQTLSPALKAPEKTRE--TGLSYTEDDKKASPEHRIILRTRIAA----SKTIDIR 331
+ L L+ KT E SY D+ SPE + + I+ ++ +
Sbjct: 798 DTEAVMAFLEAKLREDNKTDEGPDTPSYNRDNS-ISPESDVDTASTISLVTGETERKSTQ 856
Query: 332 EERTLTPISGGQRSSVVPSV-ILKPENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNR 390
+ ++ T + + S+ PS + K + R+ E K ++ +T R + V + R
Sbjct: 857 KRKSFTSLYKDRCSTGSPSKDVTKSSSSGAREKMEKKTKSRSTDVGSRADGRKFVQSSGR 916
Query: 391 IRQQLRFLGNSKSDQEEKEILPAAEISDSSS-DEEEASTPPLPRRAPRTVSRNLRSSLKS 449
IRQ L +D ++ +P + ISD S D+E S P R + ++ S L+
Sbjct: 917 IRQPSVDL----TDDDQTSSVPHSAISDIMSSDQETYSCKPHGRTPLTSADEHVHSKLEG 972
Query: 450 SLHTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEP--ASVLEEARL 493
S T +K +P + +S +L P S+L ARL
Sbjct: 973 SKVTKSKT--------SPVVSGSSSKSTTLPRPRPTRTSLLRRARL 1010
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 39.7 bits (91), Expect = 0.012
Identities = 67/298 (22%), Positives = 104/298 (34%), Gaps = 72/298 (24%)
Query: 180 QESAAKCQKPVRAKSKSAESPSWTP----AEHVAK--RIESRHSASKSRQTPTHPLTPRA 233
+ES KP+ +KS ES TP HV K ++ES+ + P T
Sbjct: 542 RESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTET--- 598
Query: 234 RKRLELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAP 293
P +++V E SP K +K T A
Sbjct: 599 ------------------------KPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAK 634
Query: 294 EKTRETGLSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVIL 353
EKT + +DKK E K + +E++ TPI ++
Sbjct: 635 EKTVKKETKVKPEDKKEEKE---------KPKKEVAKKEDK--TPIKKEEKP-------- 675
Query: 354 KPENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPA 413
K E +KK KE K E P + +K + ++++++ + +EEKE P
Sbjct: 676 KKEEVKKEVKKEIK--KEEKKEPKKEVKKET--PPKEVKKEVKKEEKKEVKKEEKE--PK 729
Query: 414 AEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAA 471
EI D +++STP + P + KVPKK + AA
Sbjct: 730 KEIKKLPKDAKKSSTPLSEAKKPAALK--------------PKVPKKEESVKKDSVAA 773
Score = 39.3 bits (90), Expect = 0.016
Identities = 39/227 (17%), Positives = 92/227 (40%), Gaps = 11/227 (4%)
Query: 261 RIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEKTRETGLSYTEDDKKA-SPEHRIILR 319
R + K E+T + +P K+++ + +K +T + +K+ S E ++
Sbjct: 558 RKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVK 617
Query: 320 TRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKKRDAKEAK--AQNEATSTPH 377
+A + D++ + + +V +KPE+ K+ K K A+ E +
Sbjct: 618 AEVAEKQATDVKPK-------AAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIK 670
Query: 378 RIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPR 437
+ + ++++++ + +E K+ P E+ EE+ + +
Sbjct: 671 KEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKK 730
Query: 438 TVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEP 484
+ + + + KSS +LKP+ P+ ++ S+AA +P
Sbjct: 731 EIKKLPKDAKKSSTPLSEAKKPAALKPKVPK-KEESVKKDSVAAGKP 776
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 39.3 bits (90), Expect = 0.016
Identities = 79/383 (20%), Positives = 126/383 (32%), Gaps = 48/383 (12%)
Query: 121 DSNINAETIIG--LVRVIPLAPKDVVPTNLKNEKTLFVKLSWNEKKFRPLSSELFAELNK 178
DS + +G V V+ L +KT+ L EK P + +E K
Sbjct: 1628 DSELKTPPSVGPPSVTVVTLESAPSALEKTTGDKTVEAPLVTEEKTVEPAT---VSEEAK 1684
Query: 179 PQESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTP---THPLTPRARK 235
P A PV + P P + A S Q P P TP A
Sbjct: 1685 PASEPAPA--PVEQLEQVDLPPGADPDKEAAMMPAGVEEGSSGDQPPYLDAKPPTPGASF 1742
Query: 236 RLELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEK 295
N+ +P+ DS + + SE + K +PD P +
Sbjct: 1743 SQAESNV-DPEP---------DSTQPLSKPAQKSEEANEPKAEKPDATADAEPDANQKAE 1792
Query: 296 TRETGLSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKP 355
+D + P +AA + +R+ TP+ S V V K
Sbjct: 1793 AAPESQPPASEDLEVDPP--------VAAKDKKPNKSKRSKTPVQAAAVSIVEKPVTRKS 1844
Query: 356 ENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKE-ILPAA 414
E I + K + + ++ ++ +T + NS +D E E LP +
Sbjct: 1845 ERIDREKLKRSNSPRGEAQKLLELKMEAEKITRTASK-------NSAADLEHPEPSLPLS 1897
Query: 415 E--------ISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRT 466
+ + D E S P PR + L L+ + T P++ P+T
Sbjct: 1898 RTRRRNVRSVYATMGDHENRSPVKEPVEQPRVTRKRLERELQEAAAVPT-TPRRGRPPKT 1956
Query: 467 PRCAAPQIRSRSLAAQEPASVLE 489
R A + + A+EPA L+
Sbjct: 1957 RRRADEEEENE---AKEPAETLK 1976
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 39.3 bits (90), Expect = 0.016
Identities = 51/201 (25%), Positives = 92/201 (45%), Gaps = 16/201 (7%)
Query: 232 RARKRLELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALK 291
RA+++LE G+ +MSQ++ + +I+ K+ E +++ D Q S L+
Sbjct: 1054 RAKRKLE----GDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHS--LQ 1107
Query: 292 APEKTRETGLSYTEDDKKASPEHRIILRTRIAASKTIDIRE----ERTLTPISGGQRSSV 347
+K +E E +++ EH LR +I ++ RE L SG + +
Sbjct: 1108 FQKKIKELQARIEELEEEIEAEHT--LRAKIEKQRSDLARELEEISERLEEASGATSAQI 1165
Query: 348 VPSVILKPENIK-KRDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQE 406
+ + E K +RD +EA Q+EAT+ R ++ SV + +Q+ L K E
Sbjct: 1166 EMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELG---EQIDNLQRVKQKLE 1222
Query: 407 EKEILPAAEISDSSSDEEEAS 427
+++ EI D +S+ E S
Sbjct: 1223 KEKSELKMEIDDMASNIEALS 1243
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 38.5 bits (88), Expect = 0.027
Identities = 70/309 (22%), Positives = 117/309 (37%), Gaps = 56/309 (18%)
Query: 175 ELNKPQESAAKCQKPVRAKSKSAES------PSWTPAEHVAKRIESRHSASKSRQTPTHP 228
E + K +KP+++ SK A S PS P +R S KSR++ +
Sbjct: 311 ERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRSRSPL 370
Query: 229 LTPRARKRLELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSP 288
L R K Q S + SPGR + + KR +P++ + SP
Sbjct: 371 LNDRRSK-------------QSKSPSRTLSPGRRAKSRSLER-----KRREPERRRLSSP 412
Query: 289 ALKAPEKTRETGLSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQRSSVV 348
+ R+ LS E K ASP +R R R+ +PI RS
Sbjct: 413 R----TRPRDDILSRRERSKDASPINRWSPTRR------------RSRSPIRRRSRSP-- 454
Query: 349 PSVILKPENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNRIR-----QQLRFLGN-SK 402
L+ +R ++ + ++ + R+RR+S R R ++ +F G+ S+
Sbjct: 455 ----LRRSRSPRRRSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDKFKGSLSE 510
Query: 403 SDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTV----SRNLRSSLKSSLHTLTKVP 458
+ E+E + D +EE+ RR R + L S+ + P
Sbjct: 511 GMKVEQESSSDDNLEDFDVEEEDEEALIEQRRIQRQAIVQKYKYLAEDSNMSVPSEPSSP 570
Query: 459 KKSLKPRTP 467
+ S + R+P
Sbjct: 571 QSSTRTRSP 579
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 38.5 bits (88), Expect = 0.027
Identities = 72/371 (19%), Positives = 131/371 (35%), Gaps = 33/371 (8%)
Query: 166 RPLSSELFAELNKPQESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHS--ASKSRQ 223
RP +S + + K +E + +K A+ +S + PA A+ S S + KS+
Sbjct: 406 RPEASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPASPRARLSASTASELSPKSKA 465
Query: 224 TPTHPLTPRARKRLELGNLGN----PQMSQQTSCASLDSPGRIKRK--------VAFSEI 271
P+ P T R + G P + GR++RK A E
Sbjct: 466 RPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPED 525
Query: 272 TSPSKRSQPDKLQTLSPALKAPEKTRETGLS--YTEDDKKASPEHRIILRTRIAASKTID 329
S SKR ++ ++ +PA AP + E +P +L + A + +
Sbjct: 526 KSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPV- 584
Query: 330 IREERTLTPISGGQRSSVVPSVILKPENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMN 389
T + G + +L + + R+ +E + Q R + L
Sbjct: 585 -----TPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLARE 639
Query: 390 -----------RIRQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRT 438
R R++ ++++QEE+E L + + EEA L R
Sbjct: 640 AEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQ 699
Query: 439 VSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVS 498
R + L + K +KS T + + + + ++ EP +E L
Sbjct: 700 QQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVEARSPGLQKE 759
Query: 499 AVPESLPCREQ 509
AV + P ++
Sbjct: 760 AVQKEEPIPQE 770
>gi|11321634 CD2-associated protein [Homo sapiens]
Length = 639
Score = 38.1 bits (87), Expect = 0.035
Identities = 50/211 (23%), Positives = 93/211 (44%), Gaps = 14/211 (6%)
Query: 284 QTLSPALKAPEKTRETGLSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGGQ 343
+T S ++ P+K R G+ + + K+ S + LRTR ++S+T + + E+ L S G
Sbjct: 199 ETASGSVTQPKKIR--GIGFGDIFKEGS----VKLRTRTSSSETEEKKPEKPLILQSLGP 252
Query: 344 RSSVVPSVILKPEN-IKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSK 402
++ V E IK ++ E T+ ++ ++ + I ++ G +
Sbjct: 253 KTQSVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHL--ISKETGEAGWWR 310
Query: 403 SDQEEKE-ILP---AAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLK-SSLHTLTKV 457
+ KE + P A +I++ D + PP P +AP + + K SL K
Sbjct: 311 GELNGKEGVFPDNFAVQINELDKDFPKPKKPPPPAKAPAPKPELIAAEKKYFSLKPEEKD 370
Query: 458 PKKSLKPRTPRCAAPQIRSRSLAAQEPASVL 488
K +L+ + + AAPQ+ + AS L
Sbjct: 371 EKSTLEQKPSKPAAPQVPPKKPTPPTKASNL 401
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 38.1 bits (87), Expect = 0.035
Identities = 41/161 (25%), Positives = 78/161 (48%), Gaps = 19/161 (11%)
Query: 260 GRIKRKVAFSEITSPSKRSQPDKLQTL-SPALKAPEKT--RETGLSYTED--DKKASPEH 314
G+++RKV +E +S + T SP K+ EKT + T + E+ + +P
Sbjct: 1215 GKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAE 1274
Query: 315 RIILRTRIAASK----TIDIREE--RTLTPISG-GQRSSVVPSVILKPENIKKRDAKEAK 367
+I+ ++ SK + EE ++ PIS G+ +SV+ +V KP NI K KE++
Sbjct: 1275 DVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESE 1334
Query: 368 AQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEK 408
+I++ + ++ I+ +++ NS S ++ K
Sbjct: 1335 PS-------EKIQKFTKDVSHEIIQHEVKSSKNSASSEKGK 1368
Score = 30.0 bits (66), Expect = 9.6
Identities = 49/262 (18%), Positives = 93/262 (35%), Gaps = 22/262 (8%)
Query: 180 QESAAKCQKPVRAKSKSA---ESPSWTPAEHVA---KRIESRHSASKSRQTPTHPLTPRA 233
+E K +P+ + K A ++ S P+ V K E K + +H +
Sbjct: 1295 EEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHE 1354
Query: 234 RKRLELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAP 293
K + ++ + L+ KRK + T P K S D+L
Sbjct: 1355 VKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNS----TQPEKESNLDRLNEQGNFKSLS 1410
Query: 294 EKTRETGLSYTEDDKKASP--------EHRIILRTR-IAASKTIDIREERTLTPISGGQR 344
+ ++E S D +AS + + TR ++SK D + E T S +
Sbjct: 1411 QSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRN 1470
Query: 345 SSVVPSVILKP---ENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNS 401
KP ++ K+ ++K N + S + + R ++ + + +
Sbjct: 1471 KDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKN 1530
Query: 402 KSDQEEKEILPAAEISDSSSDE 423
EK +L A +SS ++
Sbjct: 1531 PCKDREKHVLEARNNKESSGNK 1552
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 38.1 bits (87), Expect = 0.035
Identities = 41/161 (25%), Positives = 78/161 (48%), Gaps = 19/161 (11%)
Query: 260 GRIKRKVAFSEITSPSKRSQPDKLQTL-SPALKAPEKT--RETGLSYTED--DKKASPEH 314
G+++RKV +E +S + T SP K+ EKT + T + E+ + +P
Sbjct: 1249 GKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAE 1308
Query: 315 RIILRTRIAASK----TIDIREE--RTLTPISG-GQRSSVVPSVILKPENIKKRDAKEAK 367
+I+ ++ SK + EE ++ PIS G+ +SV+ +V KP NI K KE++
Sbjct: 1309 DVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESE 1368
Query: 368 AQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEK 408
+I++ + ++ I+ +++ NS S ++ K
Sbjct: 1369 PS-------EKIQKFTKDVSHEIIQHEVKSSKNSASSEKGK 1402
Score = 30.0 bits (66), Expect = 9.6
Identities = 49/262 (18%), Positives = 93/262 (35%), Gaps = 22/262 (8%)
Query: 180 QESAAKCQKPVRAKSKSA---ESPSWTPAEHVA---KRIESRHSASKSRQTPTHPLTPRA 233
+E K +P+ + K A ++ S P+ V K E K + +H +
Sbjct: 1329 EEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHE 1388
Query: 234 RKRLELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAP 293
K + ++ + L+ KRK + T P K S D+L
Sbjct: 1389 VKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNS----TQPEKESNLDRLNEQGNFKSLS 1444
Query: 294 EKTRETGLSYTEDDKKASP--------EHRIILRTR-IAASKTIDIREERTLTPISGGQR 344
+ ++E S D +AS + + TR ++SK D + E T S +
Sbjct: 1445 QSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRN 1504
Query: 345 SSVVPSVILKP---ENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNS 401
KP ++ K+ ++K N + S + + R ++ + + +
Sbjct: 1505 KDSASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKN 1564
Query: 402 KSDQEEKEILPAAEISDSSSDE 423
EK +L A +SS ++
Sbjct: 1565 PCKDREKHVLEARNNKESSGNK 1586
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 37.7 bits (86), Expect = 0.046
Identities = 76/367 (20%), Positives = 131/367 (35%), Gaps = 71/367 (19%)
Query: 178 KPQESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRL 237
KPQ AAK P +AKS ++S S + E + + QT P RA ++
Sbjct: 151 KPQAKAAKAP-PKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKI 209
Query: 238 ELGNLGNPQMSQQTSCASLDSPG--------------RIKRKVAFSEITSPSKRS----- 278
G + S +S +S DS ++ K T+P+++S
Sbjct: 210 ANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSED 269
Query: 279 ---------------QPDKLQTLSPALKAPEKTRETGLSYTEDDKKASPEHRIILRTRIA 323
+P ++ P AP + G T+ KKA + + + + +
Sbjct: 270 SSSDEEEEQKKPMKNKPGPYSSVPPP-SAPPPKKSLG---TQPPKKAVEKQQPVESSEDS 325
Query: 324 ASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKKRDAKEAKAQNEATSTPHRIRRKS 383
+ ++ EE P +VV KP KK + + + +S K
Sbjct: 326 SDESDSSSEEEKKPPTK-----AVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKP 380
Query: 384 SVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEI----------SDSSSDEEEASTPPLPR 433
+ T N + +KS + P + +DSSS EEE+S+ +
Sbjct: 381 AGTTKNSSNKPAV---TTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEK 437
Query: 434 RAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARL 493
+ +++ K++L +P K APQ SR ++ +S EE
Sbjct: 438 TKKMVATTKPKATAKAAL----SLPAKQ---------APQ-GSRDSSSDSDSSSSEEEEE 483
Query: 494 RLHVSAV 500
+ SAV
Sbjct: 484 KTSKSAV 490
Score = 30.4 bits (67), Expect = 7.3
Identities = 47/222 (21%), Positives = 80/222 (36%), Gaps = 32/222 (14%)
Query: 259 PGRIKRKVAFSEITSPSKRSQPDKLQTLSP----------ALKAPEKTRETGLSYTEDDK 308
PG+ K + S + S ++ Q P A KAP K ++ S ++
Sbjct: 116 PGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSS 175
Query: 309 KASP---EHRIILRTRIAASKTIDIREERTLTPISGGQRSSVVPSVILKPENIKKRDAKE 365
+ P + I + A + R I+ G+ +S S + D++E
Sbjct: 176 EDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSS---SSSSSSSDDSEE 232
Query: 366 AKAQNEATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEE 425
KA +TP + K V+ ++ S S + DSSSDEEE
Sbjct: 233 EKA----AATPKKTVPKKQVVAKAPVKAATTPTRKSSSSE------------DSSSDEEE 276
Query: 426 ASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTP 467
P+ + S S+ T+ PKK+++ + P
Sbjct: 277 EQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQP 318
>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo
sapiens]
Length = 2365
Score = 37.7 bits (86), Expect = 0.046
Identities = 75/330 (22%), Positives = 127/330 (38%), Gaps = 42/330 (12%)
Query: 169 SSELFAELNKPQESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHS--ASKSRQTPT 226
SS A + P+ S A+ P RA S + + P A+R R S +S +R T
Sbjct: 565 SSPNRATRDNPRTSCAQRDNP-RASSPNRATRD-NPTTSCAQRDNPRASRTSSPNRATRD 622
Query: 227 HPLTPRARK---RLELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDKL 283
+P T A++ R N Q S +TSCA D P + + + D
Sbjct: 623 NPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNP 682
Query: 284 QTLSPALKAPEKTRETGLSYTEDDKKASPEHRIIL---RTRIA---------ASKTIDIR 331
+ SP+ ++ T + +D + +SP RT A ++TI
Sbjct: 683 RASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRD 742
Query: 332 EERTLTPISGGQRSSVVPSVILKPENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNRI 391
RT R+S P+ ++ EN++ ++ N TS+P+R R + T
Sbjct: 743 NPRTSCAQRDNPRAS-SPNRTIQQENLRTSCTRQ---DNPRTSSPNRATR-DNPRTSCAQ 797
Query: 392 RQQLRFLGNSKSDQEE------KEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRS 445
R LR ++ Q++ ++ +P + S + D + S P R+
Sbjct: 798 RDNLRASSPIRATQQDNPRTCIQQNIPRS--SSTQQDNPKTSCTKRDNLRPTCTQRDRTQ 855
Query: 446 SLK--------SSLHTLTKVPKKSLKPRTP 467
S SS T+ K++L+P +P
Sbjct: 856 SFSFQRDNPGTSSSQCCTQ--KENLRPSSP 883
Score = 35.0 bits (79), Expect = 0.30
Identities = 68/332 (20%), Positives = 123/332 (37%), Gaps = 24/332 (7%)
Query: 166 RPLSSELFAELNKPQESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTP 225
R S + + P+ S A+ P RA S + P A R R S+
Sbjct: 635 RASSPNRTTQQDSPRTSCARRDDP-RASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQ 693
Query: 226 THPLTPRARK---RLELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQPDK 282
+P T A++ R N Q + +TSCA D+P R + +Q D
Sbjct: 694 ENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDN 753
Query: 283 LQTLSPALKAPEKTRETGLSYTEDDKKASPEHRIILRTRIAASKTIDIREERTLTPISGG 342
+ SP ++ T + ++ + +SP R + ++ ++R +PI
Sbjct: 754 PRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRAS---SPIRAT 810
Query: 343 QRSSVVPSVILKPENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQ---QLRFLG 399
Q+ + P ++ +NI + + + N TS R + + +R + Q G
Sbjct: 811 QQDN--PRTCIQ-QNIPR--SSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPG 865
Query: 400 NSKSD--QEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHT---- 453
S S +++ + P++ + + S+P + S LR + T
Sbjct: 866 TSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPS 925
Query: 454 ---LTKVPKKSLKPRTPRCAAPQIRSRSLAAQ 482
++VP S+ R + PQ S S AQ
Sbjct: 926 RSKQSEVPWASIALRPTQGDRPQTSSPSRPAQ 957
Score = 30.0 bits (66), Expect = 9.6
Identities = 59/273 (21%), Positives = 94/273 (34%), Gaps = 42/273 (15%)
Query: 213 ESRHSASKSRQTPTHPLTPRARKRLELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEIT 272
E+ ++S TP T R P+ S + LD+P
Sbjct: 308 ETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNP------------- 354
Query: 273 SPSKRSQPDKLQTLSPALKAPEKTRETGLSYTEDDKKASPEHRIILRTRIAASKTIDIRE 332
+ +Q D QT P + T +D + +SP ++T
Sbjct: 355 -RTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSP------------NRTTQREN 401
Query: 333 ERTLTPISGGQRSSVVPSVILKPENIKKRDAKEAKAQ--NEATSTPHRIRRKSSVLTMNR 390
RT S QR + S P + + + + AQ N S+P R R + + +
Sbjct: 402 SRT----SCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQ 457
Query: 391 IRQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVS----RNLRSS 446
R R S++ + S + D AS+P R T S N R+S
Sbjct: 458 -RDNPR---ASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRAS 513
Query: 447 LKSSLHTLTK-VPKKSLKPR-TPRCAAPQIRSR 477
SS + T+ P+ S R PR ++P +R
Sbjct: 514 RTSSPNRATRDNPRTSCAQRDNPRASSPNRAAR 546
>gi|239758038 PREDICTED: mucin 3A, cell surface associated, partial
[Homo sapiens]
Length = 909
Score = 37.0 bits (84), Expect = 0.079
Identities = 64/293 (21%), Positives = 105/293 (35%), Gaps = 30/293 (10%)
Query: 193 KSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLELGNLGNPQMSQQTS 252
K+ S +PS+T + + + HSA + T T R ++ + + ++
Sbjct: 260 KTTSHSTPSFTSS--ITTTETTSHSAHSFTSSITTTETTSHNTRSFTSSITTTETNSHST 317
Query: 253 CASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKAPEKTRETGLSYTEDDKKASP 312
+ S + +E TS S S + T T ET ++ T
Sbjct: 318 TSFTSS-------ITTTETTSHSTPSFSSSITTTETXXXXXXXTSETAVTPTPV------ 364
Query: 313 EHRIILRTRIAASKTIDIREERTLTPISGGQRSSVV-----PSVILKPENIKKRDAKEAK 367
T + S I RTLTP S G +S+ PS+ + R +
Sbjct: 365 -------TPSSLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFPSIPTDISTLPTRTHIISS 417
Query: 368 AQN-EATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEA 426
+ + ++T T + S TM+ +R LR N+ I+ E + +
Sbjct: 418 SPSIQSTETSSLVGTTSP--TMSTVRMTLRITENTPISSFSTSIVVIPETPTQTPPVLTS 475
Query: 427 STPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSL 479
+T AP TV+ S S+LHTLT S T + P S +L
Sbjct: 476 ATGTQTSPAPTTVTFGSTDSSTSTLHTLTPSTALSTIVSTSQVPIPSTHSSTL 528
>gi|122937243 dual specificity phosphatase 27 [Homo sapiens]
Length = 1158
Score = 36.2 bits (82), Expect = 0.13
Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 9/104 (8%)
Query: 340 SGGQRSSVVPSVILKPENIKKRDAKEAKAQNEA--TSTPHRIRRKSSVLTMNRIRQQLRF 397
SG R S +L+ K K +K+Q+E TS+ H N +R RF
Sbjct: 955 SGSSRGKYTRSSLLRETESKSSSYKFSKSQSEEQDTSSYHEANG-------NSVRSTSRF 1007
Query: 398 LGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSR 441
+S + E + +++SS EE+ P RR P + R
Sbjct: 1008 SSSSTREGREMHKFSRSTYNETSSSREESPEPYFFRRTPESSER 1051
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 36.2 bits (82), Expect = 0.13
Identities = 83/375 (22%), Positives = 136/375 (36%), Gaps = 63/375 (16%)
Query: 178 KPQESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRL 237
+ QE A K + + K ++ S P E + I+S + ++P+ P RK+
Sbjct: 342 RSQEEARKSHLARQQQEKEMKTTS--PLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKA 399
Query: 238 ELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEITSPSKRSQ----------PDKLQTLS 287
L L S++ ++P + K A S P S+ P L LS
Sbjct: 400 SLVALPEQTASEE------ETPPPLLTKEASSPPPHPQLHSEEEIEPMEGPAPPVLIQLS 453
Query: 288 PALKAPEKTRE--------------TGLSYTEDDKKASPEHRI---ILRTRIAASKTIDI 330
P TRE + LS D K SP ++ + + S D
Sbjct: 454 PP-NTDADTRELLVSQHTVQLVGGLSPLSSPSDTKAESPAEKVPEESVLPLVQKSTLADY 512
Query: 331 REERTLTPISGGQRSSVVPSVILKPENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNR 390
++ L P S RS+ + ++ + K +E Q R R ++L +R
Sbjct: 513 SAQKDLEPES--DRSAQPLPLKIEELALAKGITEECLKQPSLEQKEGR-RASHTLLPSHR 569
Query: 391 IRQQL-----RFLGNSKSDQEEKEILPAAEISDSSS-------DEEEASTPPLPRRAPRT 438
++Q R +S S + P + S S S D +A T PR P+
Sbjct: 570 LKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKM 629
Query: 439 VSRNL---RSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRL 495
SR+ RS +S + + +KSL P R ++ ++P+S E A
Sbjct: 630 GSRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTE----TKDPSSGQEVA---- 681
Query: 496 HVSAVPESLPCREQE 510
VP+ C +E
Sbjct: 682 -TPPVPQLQVCEPKE 695
Score = 35.8 bits (81), Expect = 0.17
Identities = 74/353 (20%), Positives = 123/353 (34%), Gaps = 40/353 (11%)
Query: 180 QESAAKCQKPVRAKSKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRA------ 233
+E K + ++ KSKS P T A + + +TP LT A
Sbjct: 370 EEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTKEASSPPPH 429
Query: 234 -----RKRLELGNLGNPQMSQQTSCASLDSPGR--IKRKVAFSEITSPSKRSQPDKLQTL 286
+ +E P + Q S + D+ R + + + S S P +
Sbjct: 430 PQLHSEEEIEPMEGPAPPVLIQLSPPNTDADTRELLVSQHTVQLVGGLSPLSSPSDTKAE 489
Query: 287 SPALKAPEKT------RETGLSYT-------EDDKKASPEHRIILRTRIAASKTIDIREE 333
SPA K PE++ + T Y+ E D+ A P I +A T + ++
Sbjct: 490 SPAEKVPEESVLPLVQKSTLADYSAQKDLEPESDRSAQPLPLKIEELALAKGITEECLKQ 549
Query: 334 RTLTPISGGQRSSVVPSVILKPENIKKRDAKEAKAQNEATSTPHRIRRKSSVLTMNRIRQ 393
+L G + S +L +K+ + + ++S+ R R +S + +R
Sbjct: 550 PSLEQKEGRRAS----HTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHS 605
Query: 394 QLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSL------ 447
LR + Q P S E+ + R R+ S N R SL
Sbjct: 606 PLRSKQRDVA-QARTHANPRGRPKMGSRSTSESRS--RSRSRSRSASSNSRKSLSPGVSR 662
Query: 448 -KSSLHTLTKVPKKSLKPRTPRCAAPQIRSRSLAAQEPASVLEEARLRLHVSA 499
S+ +T TK P + TP Q+ +S ++ RL SA
Sbjct: 663 DSSTSYTETKDPSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQPESA 715
>gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]
Length = 1486
Score = 36.2 bits (82), Expect = 0.13
Identities = 68/301 (22%), Positives = 106/301 (35%), Gaps = 30/301 (9%)
Query: 194 SKSAESPSWTPAEHVAKRIESRHSASKSRQTPTHPLTPRARKRLELGNLGNPQMSQQTSC 253
S ++ + S T E + S S+ + +TP H TP G T
Sbjct: 517 STTSFTSSITTTETTSHSTPSFSSSITTTETPLHS-TP-----------GLTSWVTTTKT 564
Query: 254 ASLDSPGRIKRKVAFSEITSPSKRSQPDKLQTLSPALKA-PEKTRETGLSYTEDDKKASP 312
S +PG + + +E TS S + T ++ P + T S A
Sbjct: 565 TSHITPG-LTSSITTTETTSHSTPGFTSSITTTETTSESTPSLSSSTIYSTVSTSTTAIT 623
Query: 313 EHRIILRTRI--------AASKTIDIREERTLTPISGGQRSSVV-----PSVILKPENIK 359
H T + + S I RTLTP S G +S+ PS+ +
Sbjct: 624 SHFTTSETAVTPTPVTPSSLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFPSIPTDISTLP 683
Query: 360 KRDAKEAKAQN-EATSTPHRIRRKSSVLTMNRIRQQLRFLGNSKSDQEEKEILPAAEISD 418
R + + + ++T T + S TM+ +R LR N+ I+ E
Sbjct: 684 TRTHIISSSPSIQSTETSSLVGTTSP--TMSTVRMTLRITENTPISSFSTSIVVIPETPT 741
Query: 419 SSSDEEEASTPPLPRRAPRTVSRNLRSSLKSSLHTLTKVPKKSLKPRTPRCAAPQIRSRS 478
+ ++T AP TV+ S S+LHTLT S T + P S +
Sbjct: 742 QTPPVLTSATGTQTSPAPTTVTFGSTDSSTSTLHTLTPSTALSTIVSTSQVPIPSTHSST 801
Query: 479 L 479
L
Sbjct: 802 L 802
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 36.2 bits (82), Expect = 0.13
Identities = 54/271 (19%), Positives = 113/271 (41%), Gaps = 29/271 (10%)
Query: 212 IESRHSASKSRQTPTHPLTPRARKRLELGNLGNPQMSQQTSCASLDSPGRIKRKVAFSEI 271
+E + + QTP P + + +EL + N +M ++ K V+
Sbjct: 339 LEESIPSKPAAQTP--PASIEVDENIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQ 396
Query: 272 TSPSKRSQPDKLQTLSPALKAPEKTRETGLSYTEDDKKASPEHRIILRTR----IAASKT 327
PS ++ P +T PA+K PE+ R S + + ++ SP+ ++ R + S T
Sbjct: 397 PVPSIKNVPQIDRTKKPAVKLPEEHRIK--SESTNHEQQSPQSGKVIPDRSTKPVVFSPT 454
Query: 328 IDIREERTLTPISGGQRSSVVPSVILKPENIKKRDAKEAKAQNEATSTPHRIRRKSSVLT 387
+ + +E + + +L +N ++++ +E + + + RK
Sbjct: 455 LMLTDEE--------KARIHAETALLMEKNKQEKELRERQQEEQKEKL-----RKEEQEQ 501
Query: 388 MNRIRQQLRFLGNSKSDQEEKEILPAAEISDSSSDEEEASTPPLPRRAPRTVSRNLRSSL 447
+ +Q+ ++ Q+ KE + E + +++E S + + ++ R S
Sbjct: 502 KAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKETSA-----KRGKEITGVKRQS- 555
Query: 448 KSSLHTLTKVPKKSLKPRTPRCAAPQIRSRS 478
S H T KKS++ R RC P+I+ +S
Sbjct: 556 -KSEHE-TSDAKKSVEDRGKRCPTPEIQKKS 584
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.130 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,225,355
Number of Sequences: 37866
Number of extensions: 1499981
Number of successful extensions: 6367
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 197
Number of HSP's that attempted gapping in prelim test: 6088
Number of HSP's gapped (non-prelim): 448
length of query: 861
length of database: 18,247,518
effective HSP length: 111
effective length of query: 750
effective length of database: 14,044,392
effective search space: 10533294000
effective search space used: 10533294000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.