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Search of human proteins with 31657142
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
(1179 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 2367 0.0
gi|116295258 integrin alpha 2 precursor [Homo sapiens] 840 0.0
gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 820 0.0
gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 717 0.0
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 397 e-110
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 395 e-109
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 386 e-107
gi|34452173 integrin alpha X precursor [Homo sapiens] 375 e-103
gi|62548866 integrin, alpha D precursor [Homo sapiens] 365 e-100
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 328 2e-89
gi|148728188 integrin, alpha E precursor [Homo sapiens] 292 1e-78
gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 246 1e-64
gi|67191027 integrin alpha 4 precursor [Homo sapiens] 233 1e-60
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 233 1e-60
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 230 7e-60
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 227 6e-59
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 227 6e-59
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 224 3e-58
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 218 4e-56
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 217 5e-56
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 211 3e-54
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 211 3e-54
gi|56237029 integrin alpha 5 precursor [Homo sapiens] 206 1e-52
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 193 7e-49
gi|49170034 integrin, alpha 8 [Homo sapiens] 192 1e-48
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 187 4e-47
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 110 6e-24
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 97 7e-20
gi|62548862 matrilin 2 isoform b precursor [Homo sapiens] 94 6e-19
gi|62548860 matrilin 2 isoform a precursor [Homo sapiens] 94 6e-19
>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
Length = 1179
Score = 2367 bits (6135), Expect = 0.0
Identities = 1179/1179 (100%), Positives = 1179/1179 (100%)
Query: 1 MAPRPRARPGVAVACCWLLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGK 60
MAPRPRARPGVAVACCWLLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGK
Sbjct: 1 MAPRPRARPGVAVACCWLLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGK 60
Query: 61 WVLIGSPLVGQPKNRTGDVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLV 120
WVLIGSPLVGQPKNRTGDVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLV
Sbjct: 61 WVLIGSPLVGQPKNRTGDVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLV 120
Query: 121 TNPNGGFLACGPLYAYRCGHLHYTTGICSDVSPTFQVVNSIAPVQECSTQLDIVIVLDGS 180
TNPNGGFLACGPLYAYRCGHLHYTTGICSDVSPTFQVVNSIAPVQECSTQLDIVIVLDGS
Sbjct: 121 TNPNGGFLACGPLYAYRCGHLHYTTGICSDVSPTFQVVNSIAPVQECSTQLDIVIVLDGS 180
Query: 181 NSIYPWDSVTAFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKI 240
NSIYPWDSVTAFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKI
Sbjct: 181 NSIYPWDSVTAFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKI 240
Query: 241 VQRGGRQTMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDE 300
VQRGGRQTMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDE
Sbjct: 241 VQRGGRQTMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDE 300
Query: 301 NIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIF 360
NIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIF
Sbjct: 301 NIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIF 360
Query: 361 ALEATADQSAASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTT 420
ALEATADQSAASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTT
Sbjct: 361 ALEATADQSAASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTT 420
Query: 421 FNVESTKKNEPLASYLGYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQT 480
FNVESTKKNEPLASYLGYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQT
Sbjct: 421 FNVESTKKNEPLASYLGYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQT 480
Query: 481 LSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQM 540
LSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQM
Sbjct: 481 LSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQM 540
Query: 541 SLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHG 600
SLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHG
Sbjct: 541 SLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHG 600
Query: 601 GAVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAA 660
GAVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAA
Sbjct: 601 GAVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAA 660
Query: 661 LFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEADL 720
LFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEADL
Sbjct: 661 LFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEADL 720
Query: 721 QYRVTLDSLRQISRSFFSGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVRITLDFN 780
QYRVTLDSLRQISRSFFSGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVRITLDFN
Sbjct: 721 QYRVTLDSLRQISRSFFSGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVRITLDFN 780
Query: 781 LTDPENGPVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFN 840
LTDPENGPVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFN
Sbjct: 781 LTDPENGPVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFN 840
Query: 841 VSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKDSCESNHNITCKVGYPFLRRGEMVT 900
VSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKDSCESNHNITCKVGYPFLRRGEMVT
Sbjct: 841 VSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKDSCESNHNITCKVGYPFLRRGEMVT 900
Query: 901 FKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYH 960
FKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYH
Sbjct: 901 FKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYH 960
Query: 961 ISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPT 1020
ISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPT
Sbjct: 961 ISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPT 1020
Query: 1021 GLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILDCNTCKFATITCNLTSSDIS 1080
GLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILDCNTCKFATITCNLTSSDIS
Sbjct: 1021 GLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILDCNTCKFATITCNLTSSDIS 1080
Query: 1081 QVNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLVLSSSNQKRELAIQISKDGLPGRV 1140
QVNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLVLSSSNQKRELAIQISKDGLPGRV
Sbjct: 1081 QVNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLVLSSSNQKRELAIQISKDGLPGRV 1140
Query: 1141 PLWVILLSAFAGLLLLMLLILALWKIGFFKRPLKKKMEK 1179
PLWVILLSAFAGLLLLMLLILALWKIGFFKRPLKKKMEK
Sbjct: 1141 PLWVILLSAFAGLLLLMLLILALWKIGFFKRPLKKKMEK 1179
>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
Length = 1181
Score = 840 bits (2171), Expect = 0.0
Identities = 476/1182 (40%), Positives = 697/1182 (58%), Gaps = 67/1182 (5%)
Query: 22 VLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYK 81
+L CC+++NV + + FSGP + FGY VQQ+ N +G W+L+GSP G P+NR GDVYK
Sbjct: 23 ILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYK 82
Query: 82 CPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPN-GGFLACGPLYAYRCGH 140
CPV + C KL+L +TSIPNVTE+K NM+ G L N GGFL CGPL+A +CG+
Sbjct: 83 CPVDLSTAT-CEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCGPLWAQQCGN 141
Query: 141 LHYTTGICSDVSPTFQVVNSIAPV-QECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLER 199
+YTTG+CSD+SP FQ+ S +P Q C + +D+V+V D SNSIYPWD+V FL ++
Sbjct: 142 QYYTTGVCSDISPDFQLSASFSPATQPCPSLIDVVVVCDESNSIYPWDAVKNFLEKFVQG 201
Query: 200 MDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTARK 259
+DIGP +TQVG++QY N FNLN Y + EE++VA + Q GG T T I ARK
Sbjct: 202 LDIGPTKTQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARK 261
Query: 260 EAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLS 319
A++ A G RR KVMV+VTDGESHD LK VI C +NI RF IA+LG NR L
Sbjct: 262 YAYSAASGGRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALD 321
Query: 320 TEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQ 379
T+ ++EIK+IAS PTE++FFNVSDE AL+ TLGE+IF++E T Q +F+MEMSQ
Sbjct: 322 TKNLIKEIKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGTV-QGGDNFQMEMSQ 380
Query: 380 TGFSAHYS--QDWVMLGAVGAYDWNGTVVMQKA-SQIIIPRNTTFNVESTKKNEPLASYL 436
GFSA YS D +MLGAVGA+ W+GT+V + + +I P+ + + + +SYL
Sbjct: 381 VGFSADYSSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAFDQILQDRNH---SSYL 437
Query: 437 GYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRM-EDGNIKILQTLSGEQIGSYFGSILT 495
GY+V +A ++ ++AG PR N+TGQ+++Y + E+GNI ++Q G+QIGSYFGS+L
Sbjct: 438 GYSV-AAISTGESTHFVAGAPRANYTGQIVLYSVNENGNITVIQAHRGDQIGSYFGSVLC 496
Query: 496 TTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQH 555
+ D+DKD+ TD+LLVGAPMYM K+E+G+VY++ + + LE +
Sbjct: 497 SVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYLFTIKEGILGQHQFLEGPE--------- 547
Query: 556 NSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRK 615
EN RFG+AIAA+ D+N+DGFND+++G+PLE+ + GAVYIY+G TIR
Sbjct: 548 ---GIEN------TRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGTIRT 598
Query: 616 EYAQRIPSGGDG---KTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKV 672
+Y+Q+I G DG L++FG+S+ G DLNGD +TDV+IG G WS+ +A V +
Sbjct: 599 KYSQKI-LGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAI 657
Query: 673 TMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEADLQYRVTLD----S 728
+F P K+ + KN I +CF K + + + + Y +TLD S
Sbjct: 658 EASFTPEKITLVNKNAQ--------IILKLCFSAKFRPTKQN-NQVAIVYNITLDADGFS 708
Query: 729 LRQISRSFFSGTQERKVQRNITVRKSE-CTKHSFYMLDKHDFQDSVRITLDFNLTDPENG 787
R SR F ER +Q+N+ V +++ C +H Y+ + D +S+ + +D +L +P
Sbjct: 709 SRVTSRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQEPSDVVNSLDLRVDISLENPGTS 768
Query: 788 PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSL---HVATTEKDLLIVRSQNDKFNVSLT 844
P L+ + IPF KDCG CISDL L + ++ IV +QN + S+T
Sbjct: 769 PALEAYSETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQNKRLTFSVT 828
Query: 845 VKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKDSCE-------SNHNITCKVGYPFLRRGE 897
+KN ++SAYNT +V +S NL F+ ++ D E S ++ C VGYP L+R +
Sbjct: 829 LKNKRESAYNTGIVVDFSENLFFASF-SLPVDGTEVTCQVAASQKSVACDVGYPALKREQ 887
Query: 898 MVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSAS 957
VTF I F FN L ++ A S+S+E E +DN+VN+ IP+ Y+ + S +
Sbjct: 888 QVTFTINFDFNLQNLQNQASLSFQALSESQE--ENKADNLVNLKIPLLYDAEIHLTRSTN 945
Query: 958 EYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVL 1017
I+++ VP +++S ED+G + IF L +GS P+ + I P T P++
Sbjct: 946 INFYEISSDGNVPSIVHSFEDVGPKF-IFSLKVTTGSVPVSMATVIIHIPQYTKEKNPLM 1004
Query: 1018 YPTGLSSSENANCRPHIFEDPFSI-NSGKKMTTSTDHLKRGTILDCNTCKFATITCNLTS 1076
Y TG+ + + + + +P I + ++ +++ + L+C T + +TC L
Sbjct: 1005 YLTGVQTDKAGDISCNADINPLKIGQTSSSVSFKSENFRHTKELNCRTASCSNVTCWLKD 1064
Query: 1077 SDISQ---VNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLVLSSSNQKRELAIQISK 1133
+ VNV+ +W TF S F ++ LT E+ + N + + N + + I K
Sbjct: 1065 VHMKGEYFVNVTTRIWNGTFASSTFQTVQLTAAAEINTYNPEIYVIEDNTV-TIPLMIMK 1123
Query: 1134 DGLPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFKRPLKK 1175
VP VI+ S AG+LLL+ L+ LWK+GFFKR +K
Sbjct: 1124 PDEKAEVPTGVIIGSIIAGILLLLALVAILWKLGFFKRKYEK 1165
>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
Length = 1188
Score = 820 bits (2119), Expect = 0.0
Identities = 463/1212 (38%), Positives = 703/1212 (58%), Gaps = 86/1212 (7%)
Query: 10 GVAVACCWLLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLV 69
G+ VA W L++ +FN+D + G FGYTVQQ++ KW+++G+PL
Sbjct: 6 GLVVA--WALSLWPGFTDTFNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGAPLE 63
Query: 70 GQPKNRTGDVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNP-NGGFL 128
+TGDVYKCPV G C KL+L ++ NV+E K+NM G +L TNP + FL
Sbjct: 64 TNGYQKTGDVYKCPVIHGN---CTKLNLG-RVTLSNVSERKDNMRLGLSLATNPKDNSFL 119
Query: 129 ACGPLYAYRCGHLHYTTGICSDVSPTFQVVNSIAP-VQECSTQLDIVIVLDGSNSIYPWD 187
AC PL+++ CG +YTTG+CS V+ F+ ++AP +Q C T +DIVIVLDGSNSIYPW
Sbjct: 120 ACSPLWSHECGSSYYTTGMCSRVNSNFRFSKTVAPALQRCQTYMDIVIVLDGSNSIYPWV 179
Query: 188 SVTAFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQ 247
V FL ++L++ IGP Q QVG+VQYGE+V HEF+LN Y S ++V+ AA I QRGG +
Sbjct: 180 EVQHFLINILKKFYIGPGQIQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTE 239
Query: 248 TMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSI 307
T TA GI+ AR EAF +G R+G KKVM+++TDGESHD+ L+KVIQ E +N+ R+++
Sbjct: 240 TRTAFGIEFARSEAFQ--KGGRKGAKKVMIVITDGESHDSPDLEKVIQQSERDNVTRYAV 297
Query: 308 AILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATAD 367
A+LG YNR ++ E F+ EIK IAS+P +KHFFNV+DE AL IV LG+RIF+LE T +
Sbjct: 298 AVLGYYNRRGINPETFLNEIKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGT-N 356
Query: 368 QSAASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTK 427
++ SF +EMSQTGFS+H +D V+LGAVGAYDWNG V+ + ++ +IP ++ E +
Sbjct: 357 KNETSFGLEMSQTGFSSHVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPE 416
Query: 428 KNEPLASYLGYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDG-NIKILQTLSGEQI 486
+ + +YLGYTV S +S +Y+AG PR+NHTG+VI++ M + ++ I Q + G+QI
Sbjct: 417 ELKNHGAYLGYTVTSVVSSRQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQI 476
Query: 487 GSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIK 546
GSYFGS +T+ DID D TD+LLVGAPMY E E+GKVYVY L Q F Y +L+
Sbjct: 477 GSYFGSEITSVDIDGDGVTDVLLVGAPMYFN-EGRERGKVYVYELRQNLFVYNGTLK--- 532
Query: 547 QTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIY 606
+S + +N ARFG++IA+V+DLN D +ND+V+GAPLED+H GA+YI+
Sbjct: 533 ---------DSHSYQN------ARFGSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIF 577
Query: 607 HGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRD 666
HG +I K QRI + L++FG SIHG++DLN DGL D+ +G LG A + WSR
Sbjct: 578 HGFRGSILKTPKQRITASELATGLQYFGCSIHGQLDLNEDGLIDLAVGALGNAVILWSRP 637
Query: 667 VAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEADLQYRVTL 726
V + +++FEP+K+NI ++C G++ C+ A +CF + ++Y T+
Sbjct: 638 VVQINASLHFEPSKINIFHRDCKRSGRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATM 697
Query: 727 DSLRQISRSFFSGTQERKVQRNITVRKSE--CTKHSFYMLDKHDFQDSVRITLDFNLTDP 784
D R R+ +R R + + + C + +F++LD D+ V +++++L DP
Sbjct: 698 DERRYTPRAHLDEGGDRFTNRAVLLSSGQELCERINFHVLDTADYVKPVTFSVEYSLEDP 757
Query: 785 ENGPVLDDSLPNSVHEYIPFAKDCGNKEKCISDL-------------------------- 818
++GP+LDD P ++ +PF C E C+ DL
Sbjct: 758 DHGPMLDDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDC 817
Query: 819 SLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKDSC 878
S + + + + I+ S + V T++N ++AY+T + S NL F+ + IQK+
Sbjct: 818 SAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQFASL--IQKEDS 875
Query: 879 ESN----------HNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEE 928
+ + C V YPF R V F++ F+F+ S + ++ I L+A SDS E
Sbjct: 876 DGSIECVNEERRLQKQVCNVSYPFFRAKAKVAFRLDFEFSKSIFLHHLEIELAAGSDSNE 935
Query: 929 PPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYL 988
T DNV + +KYE + F S+S H + N + + + IG + +
Sbjct: 936 RDSTKEDNVAPLRFHLKYEADVLFTRSSSLSHYEVKPNSS----LERYDGIGPPFSCIFR 991
Query: 989 IRKSGSFPMPELKLSISFPNMTSNGYPVL-YPTGLSSSENANCRPHIFEDPFSINSGKKM 1047
I+ G FP+ + + I+ P T +G +L L+ N +C + + ++ +
Sbjct: 992 IQNLGLFPIHGMMMKITIPIATRSGNRLLKLRDFLTDEANTSC------NIWGNSTEYRP 1045
Query: 1048 TTSTDHLKRGTILDCNTCKFATITCNLTSSDISQVNVSLI--LWKPTFIKSYFSSLNLTI 1105
T + L+R L+ + +I CN+ ++N L+ LW + + S+ + +
Sbjct: 1046 TPVEEDLRRAPQLNHSNSDVVSINCNIRLVPNQEINFHLLGNLWLRSLKALKYKSMKIMV 1105
Query: 1106 RGEL-RSENASLVLSSSNQKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALW 1164
L R ++ + + R++ +ISK +VP+W+I+ S GLLLL LL+LALW
Sbjct: 1106 NAALQRQFHSPFIFREEDPSRQIVFEISKQE-DWQVPIWIIVGSTLGGLLLLALLVLALW 1164
Query: 1165 KIGFFKRPLKKK 1176
K+GFF+ +++
Sbjct: 1165 KLGFFRSARRRR 1176
>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
Length = 1167
Score = 717 bits (1850), Expect = 0.0
Identities = 428/1182 (36%), Positives = 657/1182 (55%), Gaps = 66/1182 (5%)
Query: 26 CVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVG 85
C FN+D + F GP E FGY+V Q+ +W+L+G+P G +R GDVY+CPVG
Sbjct: 20 CSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAPWDGPSGDRRGDVYRCPVG 79
Query: 86 RGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLV-TNPNGGFLACGPLYAYRCGHLHYT 144
+ PC K L + + N + NM G +L+ T+ +GGF+AC PL++ CG ++
Sbjct: 80 GAHNAPCAKGHLG-DYQLGNSSHPAVNMHLGMSLLETDGDGGFMACAPLWSRACGSSVFS 138
Query: 145 TGICSDVSPTFQVVNSIAPV-QECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLERMDIG 203
+GIC+ V +FQ S+AP Q C T +D+VIVLDGSNSIYPW V FL L+ ++ I
Sbjct: 139 SGICARVDASFQPQGSLAPTAQRCPTYMDVVIVLDGSNSIYPWSEVQTFLRRLVGKLFID 198
Query: 204 PKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFT 263
P+Q QVG+VQYGE+ HE++L + + EEV+ AAK + +R GR+T TA I A E F+
Sbjct: 199 PEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQAIMVACTEGFS 258
Query: 264 EARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKF 323
++ G R +++V+VTDGESHD L ++ CE + R+ IA+LG Y R F
Sbjct: 259 QSHGGRPEAARLLVVVTDGESHDGEELPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSF 318
Query: 324 VEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFS 383
+ EI++IAS+P E+ FFNV+DE AL IV LG+RIF LE + ++ +SF +EMSQ GFS
Sbjct: 319 LREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHAENESSFGLEMSQIGFS 378
Query: 384 AHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSA 443
H +D ++ G VGAYDW G+V+ + + P E + A+YLGY+V+S
Sbjct: 379 THRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQNHAAYLGYSVSSM 438
Query: 444 TASSGDVLYIAGQPRYNHTGQVIIYRM-EDGNIKILQTLSGEQIGSYFGSILTTTDIDKD 502
G L+++G PR+ H G+VI +++ +DG +++ Q+L GEQIGSYFGS L D D+D
Sbjct: 439 LLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGEQIGSYFGSELCPLDTDRD 498
Query: 503 SNTDILLVGAPMYMGTEKEEQGKVYVYAL-NQTRFEYQMSLEPIKQTCCSSRQHNSCTTE 561
TD+LLV APM++G + +E G+VYVY + Q+ Q +L+P
Sbjct: 499 GTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQP----------------- 541
Query: 562 NKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRI 621
P ARFG A+ A+ DLN DGF D+ +GAPLED H GA+Y+YHG+ +R AQRI
Sbjct: 542 --EPPQDARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRI 599
Query: 622 PSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKV 681
+ L +FG+S+ G +DL+GD L DV +G G A L SR + + ++ P +
Sbjct: 600 AAASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAI 659
Query: 682 NIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQ 741
++ +++C G+E VC+ A +CF V ++ ++ +++ +LD +R+ F G+
Sbjct: 660 SVVQRDCRRRGQEAVCLTAALCFQVTSRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSG 719
Query: 742 ERKVQR--NITVRKSECTKHSFYMLDKHDFQDSVRITLDF---NLTDPENGPVLDDSLPN 796
+R R ++V C + F++LD D+ V +T+ F N T P GPVL++ P
Sbjct: 720 QRLSPRRLRLSVGNVTCEQLHFHVLDTSDYLRPVALTVTFALDNTTKP--GPVLNEGSPT 777
Query: 797 SVHEYIPFAKDCGNKEKCISDLSLHV----ATTEKDLLIVRSQNDKFNVSLTVKNTKDSA 852
S+ + +PF+KDCG +C++DL L V + K +VR K VS T++N K++A
Sbjct: 778 SIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKENA 837
Query: 853 YNTRTIVHYSPNLVFSGI----EAIQKDSC--ESNHNITCKVGYPFLRRGEMVTFKILFQ 906
YNT + +S NL + + E+ K C S H C VG+P + G VTF + F+
Sbjct: 838 YNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAHARLCSVGHPVFQTGAKVTFLLEFE 897
Query: 907 FNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAAN 966
F+ S L+ V + L+A+SDS E TL DN S ++YE L F S ++ + +
Sbjct: 898 FSCSSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSESTLHRYEVHPY 957
Query: 967 ETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSS-- 1024
T+P G E ++ G + + L +S P + G Y LS
Sbjct: 958 GTLP------VGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHGGN---YFLSLSQVI 1008
Query: 1025 SENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILDCNTCKFATITCNLTS-SDISQVN 1083
+ NA+C +P + L+ L+ + + + C+L + ++V+
Sbjct: 1009 TNNASCIVQNLTEP------PGPPVHPEELQHTNRLNGSNTQCQVVRCHLGQLAKGTEVS 1062
Query: 1084 VSL--ILWKPTFIKSYFSSLNLTIRGELRSENAS-LVLSSSNQKRELAIQISKDGLPGRV 1140
V L ++ F ++ F SL + EL +E S L L+ +++ E +++ + P +
Sbjct: 1063 VGLLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLLEVVQT-RPILI 1121
Query: 1141 PLWVILLSAFAGLLLLMLLILALWKIGFF---KRPLKKKMEK 1179
LW+++ S GLLLL LL+ LWK+GFF K P ++K E+
Sbjct: 1122 SLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPEEEKREE 1163
>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
Length = 1152
Score = 397 bits (1021), Expect = e-110
Identities = 346/1214 (28%), Positives = 554/1214 (45%), Gaps = 128/1214 (10%)
Query: 18 LLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTG 77
LL L C FN+D +N+MTF FG +V Q + G V++G+P N+ G
Sbjct: 6 LLLTALTLCHGFNLDTENAMTFQENARG-FGQSVVQLQ---GSRVVVGAPQEIVAANQRG 61
Query: 78 DVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLV-TNPNGGFLACGPLYAY 136
+Y+C G P ++L +PV NM+ G +L T LACGP
Sbjct: 62 SLYQCDYSTGSCEP-IRLQVPVEAV---------NMSLGLSLAATTSPPQLLACGPTVHQ 111
Query: 137 RCGHLHYTTGICSDVSPTFQVVNSIAP--VQECSTQ-LDIVIVLDGSNSIYPWD--SVTA 191
C Y G+C + P ++ C + DI ++DGS SI P D +
Sbjct: 112 TCSENTYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKE 171
Query: 192 FLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTA 251
F++ ++E++ +T ++QY E F ++ + K I Q GR T TA
Sbjct: 172 FVSTVMEQLK--KSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGR-THTA 228
Query: 252 LGIDTARKEAFTEARGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAIL 310
GI +E F GAR+ K++V++TDGE D + VI + + E + R+ I +
Sbjct: 229 TGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVG 288
Query: 311 GSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSA 370
++ +EK +E+ +IAS+P H F V++ AL TI L E+IFA+E T S+
Sbjct: 289 DAFR-----SEKSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSS 343
Query: 371 ASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNE 430
+SFE EMSQ GFSA + + +L VG+YDW G V + + + +TF + ++
Sbjct: 344 SSFEHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKE-----KSTFINMTRVDSD 398
Query: 431 PLASYLGYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYF 490
+YLGY + L + G PRY H G V ++R G + + G QIG+YF
Sbjct: 399 MNDAYLGYAAAIILRNRVQSL-VLGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYF 457
Query: 491 GSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCC 550
G+ L + D+D + +TD++L+GAP Y E+ G+V V L + R +Q C
Sbjct: 458 GASLCSVDVDSNGSTDLVLIGAPHYY--EQTRGGQVSVCPLPRGRARWQ----------C 505
Query: 551 SSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHG-S 609
+ + + +P G RFG A+ + D+N D D+ IGAP E+D+ GAVY++HG S
Sbjct: 506 DAVLYG-----EQGQPWG-RFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTS 559
Query: 610 GKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAV 669
G I ++QRI L++FGQS+ G DL DGL D+T+G G L S+ V
Sbjct: 560 GSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLR 619
Query: 670 VKVTMNFEPNKVNIQKKNCH---MEGKETVCINATVCFDVKLKSKEDTIYEADLQ----Y 722
VK M F P +V C+ ++GKE VC V+ KS D + E +Q Y
Sbjct: 620 VKAIMEFNPREVARNVFECNDQVVKGKEAG--EVRVCLHVQ-KSTRDRLREGQIQSVVTY 676
Query: 723 RVTLDSLRQISRSFFSGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVR---ITLDF 779
+ LDS R SR+ F+ T + +R V T + + + +D V + L+F
Sbjct: 677 DLALDSGRPHSRAVFNET-KNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNF 735
Query: 780 NLTDPENG------PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVR 833
+L PVL + PF K+CGN C DLS+ + D L+V
Sbjct: 736 SLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVG 795
Query: 834 SQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD--------SCESN---- 881
+ FNV++TV+N + +Y T+ + +L + + +Q +CES
Sbjct: 796 GPRE-FNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTE 854
Query: 882 -----HNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDN 936
+ +C + +P VTF I F ++ + N + L A SE +
Sbjct: 855 VSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGN-KLLLKANVTSENNMPRTNKT 913
Query: 937 VVNISIPVKYEVGLQFYS-SASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSF 995
+ +PVKY V + S S +++ A+E V+ + N
Sbjct: 914 EFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN-------------L 960
Query: 996 PMPELKLSISFPNMTSNGYPVLYP-TGLSSSENANCRPHIFEDPFSINSGKKMTTSTD-- 1052
L +S+ F V++ ++ SEN + H E ++ + +D
Sbjct: 961 GQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKE---------RLPSHSDFL 1011
Query: 1053 -HLKRGTILDCNTCKFATITCNLTSSDI-SQVNVSL--ILWKPTFIKSYFSSLNLTIRGE 1108
L++ +++C+ I C++ I + N +L L +IK+ + L + E
Sbjct: 1012 AELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAE 1071
Query: 1109 LRSENASLVL---SSSNQKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWK 1165
+ ++ L + + + ++ +P +PL I+ S+ GLLLL L+ AL+K
Sbjct: 1072 ILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPNPLPL--IVGSSVGGLLLLALITAALYK 1129
Query: 1166 IGFFKRPLKKKMEK 1179
+GFFKR K M +
Sbjct: 1130 LGFFKRQYKDMMSE 1143
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 395 bits (1015), Expect = e-109
Identities = 345/1214 (28%), Positives = 554/1214 (45%), Gaps = 127/1214 (10%)
Query: 18 LLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTG 77
LL L C FN+D +N+MTF FG +V Q + G V++G+P N+ G
Sbjct: 6 LLLTALTLCHGFNLDTENAMTFQENARG-FGQSVVQLQ---GSRVVVGAPQEIVAANQRG 61
Query: 78 DVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLV-TNPNGGFLACGPLYAY 136
+Y+C G P ++L +PV NM+ G +L T LACGP
Sbjct: 62 SLYQCDYSTGSCEP-IRLQVPVEAV---------NMSLGLSLAATTSPPQLLACGPTVHQ 111
Query: 137 RCGHLHYTTGICSDVSPTFQVVNSIAP--VQECSTQ-LDIVIVLDGSNSIYPWD--SVTA 191
C Y G+C + P ++ C + DI ++DGS SI P D +
Sbjct: 112 TCSENTYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKE 171
Query: 192 FLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTA 251
F++ ++E++ +T ++QY E F ++ + K I Q GR T TA
Sbjct: 172 FVSTVMEQLK--KSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGR-THTA 228
Query: 252 LGIDTARKEAFTEARGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAIL 310
GI +E F GAR+ K++V++TDGE D + VI + + E + R+ I +
Sbjct: 229 TGIRKVVRELFNITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVG 288
Query: 311 GSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSA 370
++ +EK +E+ +IAS+P H F V++ AL TI L E+IFA+E T S+
Sbjct: 289 DAFR-----SEKSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSS 343
Query: 371 ASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNE 430
+SFE EMSQ GFSA + + +L VG+YDW G V + + + +TF + ++
Sbjct: 344 SSFEHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKE-----KSTFINMTRVDSD 398
Query: 431 PLASYLGYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYF 490
+YLGY + L + G PRY H G V ++R G + + G QIG+YF
Sbjct: 399 MNDAYLGYAAAIILRNRVQSL-VLGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYF 457
Query: 491 GSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCC 550
G+ L + D+D + +TD++L+GAP Y QTR Q+S+ P+ +
Sbjct: 458 GASLCSVDVDSNGSTDLVLIGAPHY---------------YEQTR-GGQVSVCPLPRGQR 501
Query: 551 SSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHG-S 609
+ Q ++ + +P G RFG A+ + D+N D D+ IGAP E+D+ GAVY++HG S
Sbjct: 502 ARWQCDAVLYGEQGQPWG-RFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTS 560
Query: 610 GKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAV 669
G I ++QRI L++FGQS+ G DL DGL D+T+G G L S+ V
Sbjct: 561 GSGISPSHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLR 620
Query: 670 VKVTMNFEPNKVNIQKKNCH---MEGKETVCINATVCFDVKLKSKEDTIYEADLQ----Y 722
VK M F P +V C+ ++GKE VC V+ KS D + E +Q Y
Sbjct: 621 VKAIMEFNPREVARNVFECNDQVVKGKEAG--EVRVCLHVQ-KSTRDRLREGQIQSVVTY 677
Query: 723 RVTLDSLRQISRSFFSGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVR---ITLDF 779
+ LDS R SR+ F+ T + +R V T + + + +D V + L+F
Sbjct: 678 DLALDSGRPHSRAVFNET-KNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNF 736
Query: 780 NLTDPENG------PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVR 833
+L PVL + PF K+CGN C DLS+ + D L+V
Sbjct: 737 SLVGTPLSAFGNLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVG 796
Query: 834 SQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD--------SCESN---- 881
+ FNV++TV+N + +Y T+ + +L + + +Q +CES
Sbjct: 797 GPRE-FNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTE 855
Query: 882 -----HNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDN 936
+ +C + +P VTF I F ++ + N + L A SE +
Sbjct: 856 VSGALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGN-KLLLKANVTSENNMPRTNKT 914
Query: 937 VVNISIPVKYEVGLQFYS-SASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSF 995
+ +PVKY V + S S +++ A+E V+ + N
Sbjct: 915 EFQLELPVKYAVYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN-------------L 961
Query: 996 PMPELKLSISFPNMTSNGYPVLYP-TGLSSSENANCRPHIFEDPFSINSGKKMTTSTD-- 1052
L +S+ F V++ ++ SEN + H E ++ + +D
Sbjct: 962 GQRSLPISLVFLVPVRLNQTVIWDRPQVTFSENLSSTCHTKE---------RLPSHSDFL 1012
Query: 1053 -HLKRGTILDCNTCKFATITCNLTSSDI-SQVNVSL--ILWKPTFIKSYFSSLNLTIRGE 1108
L++ +++C+ I C++ I + N +L L +IK+ + L + E
Sbjct: 1013 AELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAE 1072
Query: 1109 LRSENASLVL---SSSNQKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWK 1165
+ ++ L + + + ++ +P +PL I+ S+ GLLLL L+ AL+K
Sbjct: 1073 ILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPNPLPL--IVGSSVGGLLLLALITAALYK 1130
Query: 1166 IGFFKRPLKKKMEK 1179
+GFFKR K M +
Sbjct: 1131 LGFFKRQYKDMMSE 1144
>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
Length = 1170
Score = 386 bits (992), Expect = e-107
Identities = 338/1201 (28%), Positives = 554/1201 (46%), Gaps = 149/1201 (12%)
Query: 28 SFNVDVKNSMTFSGPVEDM-FGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGR 86
S+N+DV+ + +FS P FGY V Q G V++G+P G N TG +Y+C G
Sbjct: 25 SYNLDVRGARSFSPPRAGRHFGYRVLQV----GNGVIVGAPGEG---NSTGSLYQCQSGT 77
Query: 87 GESLPCVKLDLPVNTSIPNVTEVKENMT---FGSTLVTNP-NGGFLACGPLYAYRCGHLH 142
G LP VT N T G TL T+P +G LAC P + C
Sbjct: 78 GHCLP--------------VTLRGSNYTSKYLGMTLATDPTDGSILACDPGLSRTCDQNT 123
Query: 143 YTTGICSDVSPTFQ--VVNSIAPVQEC-STQLDIVIVLDGSNSIYP--WDSVTAFLNDLL 197
Y +G+C Q ++ QEC +D+V + DGS S+ P + + F+ D++
Sbjct: 124 YLSGLCYLFRQNLQGPMLQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVM 183
Query: 198 ERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTA 257
+++ Q VQ+ + EF+ + Y ++ A K V+ T T I+
Sbjct: 184 KKLS--NTSYQFAAVQFSTSYKTEFDFSDYVKRKDP-DALLKHVKHMLLLTNTFGAINYV 240
Query: 258 RKEAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGN 317
E F E GAR KV++I+TDGE+ D+ + ++I R+ I I +
Sbjct: 241 ATEVFREELGARPDATKVLIIITDGEATDSGNIDAA------KDIIRYIIGI-----GKH 289
Query: 318 LSTEKFVEEIKSIASEPTEKHFFNVSDELA-LVTIVKTLGERIFALEATADQSAASFEME 376
T++ E + AS+P + F + D L + L ++I+ +E T+ Q SF ME
Sbjct: 290 FQTKESQETLHKFASKPASE-FVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNME 348
Query: 377 MSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYL 436
+S +G SA S+ ++GAVGA DW G + KA ++ TF E A YL
Sbjct: 349 LSSSGISADLSRGHAVVGAVGAKDWAGGFLDLKADL----QDDTFIGNEPLTPEVRAGYL 404
Query: 437 GYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDG--NIKILQTLSGEQIGSYFGSIL 494
GYTV + L +G PRY H G+V++++ G + +QT+ G QIGSYFG L
Sbjct: 405 GYTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGEL 464
Query: 495 TTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQ 554
D+D+D T++LL+GAP++ G ++ G+V++Y Q FE L+
Sbjct: 465 CGVDVDQDGETELLLIGAPLFYGEQRG--GRVFIYQRRQLGFEEVSELQG---------- 512
Query: 555 HNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIR 614
+ P G RFG AI A+ D+N DG D+ +GAPLE+ GAVYI++G +
Sbjct: 513 -------DPGYPLG-RFGEAITALTDINGDGLVDVAVGAPLEEQ--GAVYIFNGRHGGLS 562
Query: 615 KEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTM 674
+ +QRI +++FG+SIHG DL GDGL DV +G + SR V + M
Sbjct: 563 PQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLM 622
Query: 675 NFEPNKVNIQKKNC--HMEGKETVCINATVCFDVK-LKSKEDTIYEADLQYRVTLDSLRQ 731
+F P ++ + + C K +N T+CF +K L + A+L Y + LD R
Sbjct: 623 SFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRT 682
Query: 732 ISRSFFSGTQERKVQRNITVRKS-ECTKHSFYM-LDKHDFQDSVRITLDFNLTDPEN--- 786
R F G + +++RNI V S CT SF+ + D + ++L+F+L + E
Sbjct: 683 RRRGLFPGGR-HELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPR 741
Query: 787 ---------GPVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQND 837
P+L SL + E IPF K+CG +KC ++L + + L + +
Sbjct: 742 DQRAQGKDIPPILRPSLHSETWE-IPFEKNCGEDKKCEANLRVSFSPARSRALRL-TAFA 799
Query: 838 KFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD-----SCES--------NHNI 884
+V L++ N ++ AY + +H+ P L F +E ++ SCE + +
Sbjct: 800 SLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRAL 859
Query: 885 TCKVGYPFLRRGEMVTFKILFQ--FNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISI 942
+C V P + G V +++F N+S+ ++V ++ + T ++E+ + L DN I
Sbjct: 860 SCNVSSPIFKAGHSVALQMMFNTLVNSSW-GDSVELHANVTCNNED-SDLLEDNSATTII 917
Query: 943 PVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSF---PMPE 999
P+ Y + + + + ++ P++ +++ Y +R S +P
Sbjct: 918 PILYPINI-LIQDQEDSTLYVSFTPKGPKI--------HQVKHMYQVRIQPSIHDHNIPT 968
Query: 1000 LKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTI 1059
L+ + P S G P+ + + C +ED +++ + + G +
Sbjct: 969 LEAVVGVPQPPSEG-PITHQWSVQMEPPVPCH---YEDL------ERLPDAAEPCLPGAL 1018
Query: 1060 LDCNTCKFATITCNL--TSSDISQVNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLV 1117
C I + T + ++ S + + S S N + L NASL
Sbjct: 1019 FRCPVVFRQEILVQVIGTLELVGEIEASSMF---SLCSSLSISFNSSKHFHLYGSNASLA 1075
Query: 1118 LSSSNQKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFKRPLKKKM 1177
+ + D + + L++ +LS GLLLL+L+ + L+K+GFFKR LK+KM
Sbjct: 1076 ----------QVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKM 1125
Query: 1178 E 1178
E
Sbjct: 1126 E 1126
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 375 bits (962), Expect = e-103
Identities = 337/1215 (27%), Positives = 550/1215 (45%), Gaps = 133/1215 (10%)
Query: 18 LLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTG 77
LL L + FN+D + F FG +V QY N WV++G+P N+TG
Sbjct: 9 LLFTALATSLGFNLDTEELTAFRVDSAG-FGDSVVQYANS---WVVVGAPQKITAANQTG 64
Query: 78 DVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGGFLACGPLYAYR 137
+Y+C G P + L +P P + ++ ST T+P+ LACGP +
Sbjct: 65 GLYQCGYSTGACEP-IGLQVP-----PEAVNMSLGLSLAST--TSPSQ-LLACGPTVHHE 115
Query: 138 CGHLHYTTGICSDVSPTFQVVNSIAPVQECSTQ-LDIVIVLDGSNSIYPWDSVTA--FLN 194
CG Y TG+C + PT QEC Q DIV ++DGS SI + T F+
Sbjct: 116 CGRNMYLTGLCFLLGPTQLTQRLPVSRQECPRQEQDIVFLIDGSGSISSRNFATMMNFVR 175
Query: 195 DLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGI 254
++ + TQ ++Q+ F ++ + L + Q G T TA I
Sbjct: 176 AVISQFQ--RPSTQFSLMQFSNKFQTHFTFEEFRRSSNPLSLLASVHQLQGF-TYTATAI 232
Query: 255 DTARKEAFTEARGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAI-LGS 312
F + GARR K+++++TDG+ D+ K VI + I R++I + L
Sbjct: 233 QNVVHRLFHASYGARRDAAKILIVITDGKKEGDSLDYKDVIPMADAAGIIRYAIGVGLAF 292
Query: 313 YNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAAS 372
NR + +E+ IAS+P+++H F V D AL I L E+IFA+E T S++S
Sbjct: 293 QNRNSW------KELNDIASKPSQEHIFKVEDFDALKDIQNQLKEKIFAIEGTETTSSSS 346
Query: 373 FEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPL 432
FE+EM+Q GFSA ++ D +LGAVG++ W+G + + + TF S + +
Sbjct: 347 FELEMAQEGFSAVFTPDGPVLGAVGSFTWSGGAFLYPPNM-----SPTFINMSQENVDMR 401
Query: 433 ASYLGYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGS 492
SYLGY+ A L + G PRY HTG+ +I+ ++ ++G QIGSYFG+
Sbjct: 402 DSYLGYSTELALWKGVQSL-VLGAPRYQHTGKAVIFTQVSRQWRMKAEVTGTQIGSYFGA 460
Query: 493 ILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSS 552
L + D+D D +TD++L+GAP Y E+ G+V V L + ++ C +
Sbjct: 461 SLCSVDVDSDGSTDLVLIGAPHYY--EQTRGGQVSVCPLPR----------GWRRWWCDA 508
Query: 553 RQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHG-SGK 611
+ + P G RFG A+ + D+N D D+VIGAP E+++ GAVY++HG G
Sbjct: 509 VLYG-----EQGHPWG-RFGAALTVLGDVNGDKLTDVVIGAPGEEENRGAVYLFHGVLGP 562
Query: 612 TIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVK 671
+I ++QRI L++FGQ++ G DL DGL D+ +G G L +R V V
Sbjct: 563 SISPSHSQRIAGSQLSSRLQYFGQALSGGQDLTQDGLVDLAVGARGQVLLLRTRPVLWVG 622
Query: 672 VTMNFEPNKVNIQKKNCHME-GKETVCINATVCFDVKLKSKEDTIYEADLQYRVTLDSL- 729
V+M F P ++ C + E + + +C + +SK + + DLQ VTLD
Sbjct: 623 VSMQFIPAEIPRSAFECREQVVSEQTLVQSNICLYIDKRSK-NLLGSRDLQSSVTLDLAL 681
Query: 730 ---RQISRSFFSGTQERKVQR-NITVRKSECTKHSFYMLDKHDFQDSVR-ITLDFNLT-- 782
R R+ F T+ R + R + K+ C +F +L +DSV ITL N T
Sbjct: 682 DPGRLSPRATFQETKNRSLSRVRVLGLKAHC--ENFNLLLPSCVEDSVTPITLRLNFTLV 739
Query: 783 ------DPENGPVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQN 836
P+L +PF K+CG C +L + + L+V S N
Sbjct: 740 GKPLLAFRNLRPMLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGS-N 798
Query: 837 DKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD--------SCES-------N 881
+ N + V N + +Y T + L + + QK +C+S
Sbjct: 799 LELNAEVMVWNDGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGT 858
Query: 882 HNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNIS 941
+ +C++ + R G +TF F + ++ + + L+A SE S +
Sbjct: 859 WSTSCRINHLIFRGGAQITFLATFDVSPKAVLGD-RLLLTANVSSENNTPRTSKTTFQLE 917
Query: 942 IPVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELK 1001
+PVKY V + ++++E + +N +E E ++ + + +L
Sbjct: 918 LPVKYAV-----------YTVVSSHEQFTKYLNFSESEEKESHVAMHRYQVNNLGQRDLP 966
Query: 1002 LSISF-PNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTD---HLKRG 1057
+SI+F + N V +S +N + R +S K ++D H+++
Sbjct: 967 VSINFWVPVELNQEAVWMDVEVSHPQNPSLR---------CSSEKIAPPASDFLAHIQKN 1017
Query: 1058 TILDCNTCKFATITCNLTSSDISQV-------NVSL-----ILWKPTFIKSYFS-SLNLT 1104
+LDC+ C++ S + + N+S IL K + S + + +
Sbjct: 1018 PVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVSVVSVAEITFDTS 1077
Query: 1105 IRGELRSENASLVLSSSNQKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALW 1164
+ +L + A + + + + K + PL I+ S+ GLLLL L+ L+
Sbjct: 1078 VYSQLPGQEAFM-------RAQTTTVLEKYKVHNPTPL--IVGSSIGGLLLLALITAVLY 1128
Query: 1165 KIGFFKRPLKKKMEK 1179
K+GFFKR K+ ME+
Sbjct: 1129 KVGFFKRQYKEMMEE 1143
>gi|62548866 integrin, alpha D precursor [Homo sapiens]
Length = 1161
Score = 365 bits (938), Expect = e-100
Identities = 329/1206 (27%), Positives = 548/1206 (45%), Gaps = 120/1206 (9%)
Query: 18 LLTVVLRCCVSFNVDVKNSMTFSGPVEDM--FGYTVQQYENEEGKWVLIGSPLVGQPKNR 75
LL VL FN+DV+ F ED FG +V Q+ G +++G+PL N+
Sbjct: 7 LLLSVLASYHGFNLDVEEPTIFQ---EDAGGFGQSVVQFG---GSRLVVGAPLEVVAANQ 60
Query: 76 TGDVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGG-FLACGPLY 134
TG +Y C G P +P++ V NM+ G TL + NG LACGP
Sbjct: 61 TGRLYDCAAATGMCQP-----IPLHIRPEAV-----NMSLGLTLAASTNGSRLLACGPTL 110
Query: 135 AYRCGHLHYTTGICSDVSPTFQVVNSIAPVQ-ECSTQ-LDIVIVLDGSNSI--YPWDSVT 190
CG Y+ G C + ++++ ++ EC Q +DIV ++DGS SI ++ +
Sbjct: 111 HRVCGENSYSKGSCLLLGSRWEIIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMK 170
Query: 191 AFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMT 250
F+ ++ + + T ++QY + F ++ ++ IVQ G T T
Sbjct: 171 GFVQAVMGQFE--GTDTLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGL-TFT 227
Query: 251 ALGIDTARKEAFTEARGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAI 309
A GI T + F GAR+ KK+++++TDG+ + D VI E I R++I +
Sbjct: 228 ATGILTVVTQLFHHKNGARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGV 287
Query: 310 LGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQS 369
G +G + + E+ +I+S P + H F V + AL +I K L E+I+A+E T ++
Sbjct: 288 -GHAFQGPTARQ----ELNTISSAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRA 342
Query: 370 AASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKN 429
++SF+ EMSQ GFS + D + LGAVG++ W+G + + + TF S +
Sbjct: 343 SSSFQHEMSQEGFSTALTMDGLFLGAVGSFSWSGGAFLYPPNM-----SPTFINMSQENV 397
Query: 430 EPLASYLGYTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSY 489
+ SYLGY+ A L + G PRY HTG+ +I+ + ++G QIGSY
Sbjct: 398 DMRDSYLGYSTELALWKGVQNL-VLGAPRYQHTGKAVIFTQVSRQWRKKAEVTGTQIGSY 456
Query: 490 FGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTC 549
FG+ L + D+D D +TD++L+GAP Y E+ G+V V L + R ++Q
Sbjct: 457 FGASLCSVDVDSDGSTDLILIGAPHYY--EQTRGGQVSVCPLPRGRVQWQC--------- 505
Query: 550 CSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGS 609
++ + P G RFG A+ + D+N D D+ IGAP E ++ GAVY++HG+
Sbjct: 506 ------DAVLRGEQGHPWG-RFGAALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLFHGA 558
Query: 610 GKT-IRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVA 668
++ I ++QRI S L++FGQ++ G DL DGL D+ +G G L S V
Sbjct: 559 SESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVGARGQVLLLRSLPVL 618
Query: 669 VVKVTMNFEPNKVNIQKKNCHMEGKETV-CINATVCFDVKLKSKEDTI--YEADLQYRVT 725
V V M F P +V C E + +ATVC ++ KS D + ++ +++ +
Sbjct: 619 KVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQ-KSSLDQLGDIQSSVRFDLA 677
Query: 726 LDSLRQISRSFFSGTQERKVQRNITVRKS-ECTKHSFYMLD-KHDFQDSVRITLDFNLT- 782
LD R SR+ F+ T+ + R T+ C + D D + + L+F+L
Sbjct: 678 LDPGRLTSRAIFNETKNPTLTRRKTLGLGIHCETLKLLLPDCVEDVVSPIILHLNFSLVR 737
Query: 783 ----DPEN-GPVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQND 837
P+N PVL + +PF K+CG C DL + ++ + L V S +
Sbjct: 738 EPIPSPQNLRPVLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTLSFSGLQTLTVGSSLE 797
Query: 838 KFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD--------SCES-------NH 882
NV +TV N + +Y T ++Y L + QK +CE+
Sbjct: 798 -LNVIVTVWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLR 856
Query: 883 NITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISI 942
+ C V +P G TF + F + + + + + A++ SE + S + +
Sbjct: 857 SSRCSVNHPIFHEGSNGTFIVTFDVSYKATLGD-RMLMRASASSENNKASSSKATFQLEL 915
Query: 943 PVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKL 1002
PVKY V + I+ E + N ++ + + +L +
Sbjct: 916 PVKYAV-----------YTMISRQEESTKYFNFATSDEKKMKEAEHRYRVNNLSQRDLAI 964
Query: 1003 SISF-PNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILD 1061
SI+F + NG V + S++ C S + + + R +LD
Sbjct: 965 SINFWVPVLLNGVAVWDVVMEAPSQSLPC--------VSERKPPQHSDFLTQISRSPMLD 1016
Query: 1062 CNTCKFATITCNLTSSDISQV-------NVSLILWKPTFIKSYF--SSLNLTIRGELRSE 1112
C+ C++ S + + N+S + T K S +T + S+
Sbjct: 1017 CSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQ 1076
Query: 1113 NASLVLSSSNQKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFKRP 1172
L + + ++ + + +D + +P +I+ S+ LLLL L+ L+K+GFFKR
Sbjct: 1077 ---LPGQEAFMRAQMEMVLEEDEVYNAIP--IIMGSSVGALLLLALITATLYKLGFFKRH 1131
Query: 1173 LKKKME 1178
K+ +E
Sbjct: 1132 YKEMLE 1137
>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
Length = 1086
Score = 328 bits (840), Expect = 2e-89
Identities = 280/1006 (27%), Positives = 467/1006 (46%), Gaps = 115/1006 (11%)
Query: 212 VQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGARRG 271
VQ+ + EF+ + Y ++ A K V+ T T I+ E F E GAR
Sbjct: 113 VQFSTSYKTEFDFSDYVKRKDP-DALLKHVKHMLLLTNTFGAINYVATEVFREELGARPD 171
Query: 272 VKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIA 331
KV++I+TDGE+ D+ + ++I R+ I I + T++ E + A
Sbjct: 172 ATKVLIIITDGEATDSGNIDAA------KDIIRYIIGI-----GKHFQTKESQETLHKFA 220
Query: 332 SEPTEKHFFNVSDELA-LVTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHYSQDW 390
S+P + F + D L + L ++I+ +E T+ Q SF ME+S +G SA S+
Sbjct: 221 SKPASE-FVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGH 279
Query: 391 VMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSATASSGDV 450
++GAVGA DW G + KA ++ TF E A YLGYTV +
Sbjct: 280 AVVGAVGAKDWAGGFLDLKADL----QDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTS 335
Query: 451 LYIAGQPRYNHTGQVIIYRMEDG--NIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDIL 508
L +G PRY H G+V++++ G + +QT+ G QIGSYFG L D+D+D T++L
Sbjct: 336 LLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELL 395
Query: 509 LVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCG 568
L+GAP++ G ++ G+V++Y Q FE L+ + P G
Sbjct: 396 LIGAPLFYGEQRG--GRVFIYQRRQLGFEEVSELQG-----------------DPGYPLG 436
Query: 569 ARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRIPSGGDGK 628
RFG AI A+ D+N DG D+ +GAPLE+ GAVYI++G + + +QRI
Sbjct: 437 -RFGEAITALTDINGDGLVDVAVGAPLEEQ--GAVYIFNGRHGGLSPQPSQRIEGTQVLS 493
Query: 629 TLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNC 688
+++FG+SIHG DL GDGL DV +G + SR V + M+F P ++ + + C
Sbjct: 494 GIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVEC 553
Query: 689 --HMEGKETVCINATVCFDVK-LKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQERKV 745
K +N T+CF +K L + A+L Y + LD R R F G + ++
Sbjct: 554 SYSTSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGR-HEL 612
Query: 746 QRNITVRKS-ECTKHSFYM-LDKHDFQDSVRITLDFNLTDPEN-----------GPVLDD 792
+RNI V S CT SF+ + D + ++L+F+L + E P+L
Sbjct: 613 RRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAGKDIPPILRP 672
Query: 793 SLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSA 852
SL + E IPF K+CG +KC ++L + + L + + +V L++ N ++ A
Sbjct: 673 SLHSETWE-IPFEKNCGEDKKCEANLRVSFSPARSRALRL-TAFASLSVELSLSNLEEDA 730
Query: 853 YNTRTIVHYSPNLVFSGIEAIQKD-----SCES--------NHNITCKVGYPFLRRGEMV 899
Y + +H+ P L F +E ++ SCE + ++C V P + G V
Sbjct: 731 YWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSV 790
Query: 900 TFKILFQ--FNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSAS 957
+++F N+S+ ++V ++ + T ++E+ + L DN IP+ Y + +
Sbjct: 791 ALQMMFNTLVNSSW-GDSVELHANVTCNNED-SDLLEDNSATTIIPILYPINI-LIQDQE 847
Query: 958 EYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSF---PMPELKLSISFPNMTSNGY 1014
+ + ++ P++ +++ Y +R S +P L+ + P S G
Sbjct: 848 DSTLYVSFTPKGPKI--------HQVKHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEG- 898
Query: 1015 PVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILDCNTCKFATITCNL 1074
P+ + + C +ED +++ + + G + C I +
Sbjct: 899 PITHQWSVQMEPPVPCH---YEDL------ERLPDAAEPCLPGALFRCPVVFRQEILVQV 949
Query: 1075 --TSSDISQVNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLVLSSSNQKRELAIQIS 1132
T + ++ S + + S S N + L NASL + +
Sbjct: 950 IGTLELVGEIEASSMF---SLCSSLSISFNSSKHFHLYGSNASLA----------QVVMK 996
Query: 1133 KDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFKRPLKKKME 1178
D + + L++ +LS GLLLL+L+ + L+K+GFFKR LK+KME
Sbjct: 997 VDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKME 1042
Score = 57.0 bits (136), Expect = 1e-07
Identities = 133/588 (22%), Positives = 216/588 (36%), Gaps = 114/588 (19%)
Query: 28 SFNVDVKNSMTFSGPVEDM-FGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGR 86
S+N+DV+ + +FS P FGY V Q G V++G+P G N TG +Y+C G
Sbjct: 25 SYNLDVRGARSFSPPRAGRHFGYRVLQV----GNGVIVGAPGEG---NSTGSLYQCQSGT 77
Query: 87 GESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGGFLACGPLYAYRCGHLHYTTG 146
G LPV N T + G TL T+P G + L+A Y T
Sbjct: 78 GHC-------LPVTLRGSNYT----SKYLGMTLATDPTDGSI----LFAAVQFSTSYKTE 122
Query: 147 ICSDVSPTFQVVNSIAPVQECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLERMD----- 201
D S + + A ++ L + N + + F +L R D
Sbjct: 123 F--DFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYV----ATEVFREELGARPDATKVL 176
Query: 202 ---IGPKQTQVGIVQYGEN-VTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTA 257
+ T G + ++ + + + K+ T+E K + + + L
Sbjct: 177 IIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASKPASEFVKILDTFEK 236
Query: 258 RKEAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGN 317
K+ FTE + KK+ VI +G S QD N++ S I +RG+
Sbjct: 237 LKDLFTELQ------KKIYVI--EGTSK---------QDLTSFNMELSSSGISADLSRGH 279
Query: 318 LSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEM 377
+ ++ ++ F ++ +L T + + E+
Sbjct: 280 -------AVVGAVGAKDWAGGFLDLKADLQDDTFI--------------GNEPLTPEVRA 318
Query: 378 SQTGFSAHY--SQDWVMLGAVGA--YDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLA 433
G++ + S+ L A GA Y G V++ + Q ++ T +
Sbjct: 319 GYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQ----GGGHWSQVQTIHGTQIG 374
Query: 434 SYLGYTVNSATA-SSGDV-LYIAGQPRY---NHTGQVIIYRMEDGNIKILQTLSGE---Q 485
SY G + G+ L + G P + G+V IY+ + + L G+
Sbjct: 375 SYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGRVFIYQRRQLGFEEVSELQGDPGYP 434
Query: 486 IGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPI 545
+G + +I TDI+ D D+ VGAP+ EEQG VY++ Q S
Sbjct: 435 LGRFGEAITALTDINGDGLVDV-AVGAPL------EEQGAVYIFNGRHGGLSPQPSQRIE 487
Query: 546 KQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGA 593
S Q FG +I VKDL DG D+ +GA
Sbjct: 488 GTQVLSGIQW---------------FGRSIHGVKDLEGDGLADVAVGA 520
>gi|148728188 integrin, alpha E precursor [Homo sapiens]
Length = 1179
Score = 292 bits (748), Expect = 1e-78
Identities = 276/1040 (26%), Positives = 465/1040 (44%), Gaps = 127/1040 (12%)
Query: 172 DIVIVLDGSNSIYPWDSVTA--FLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSS 229
+I I+LDGS SI P D A F+++++ + +VQYG + EF+L
Sbjct: 202 EIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQD 261
Query: 230 TEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGE-SHDNH 288
L + I Q G T TA + FT + G+RR KVMV++TDG D
Sbjct: 262 VMASLARVQNITQVGS-VTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPL 320
Query: 289 RLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELAL 348
L VI + + ++RF+I + + + + E+ IAS+P E H F V++ +AL
Sbjct: 321 NLTTVINSPKMQGVERFAIGVGEEF-----KSARTARELNLIASDPDETHAFKVTNYMAL 375
Query: 349 VTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAH-YSQDWVMLGAVGAYDWNGTVVM 407
++ L I ++E T + +++Q GFSA + V+LGAVGA+DW+G ++
Sbjct: 376 DGLLSKLRYNIISMEGTVGD---ALHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALL 432
Query: 408 QKASQIIIPRNTTFNVESTKKNEPLA---SYLGYTVNSATASSGDVLYIAGQPRYNHTGQ 464
R N + + A SYLGY V + + + YIAG PRY H G
Sbjct: 433 YDTRS---RRGRFLNQTAAAAADAEAAQYSYLGYAV-AVLHKTCSLSYIAGAPRYKHHGA 488
Query: 465 VIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQG 524
V + E L L GEQ+GSYFGS L DID D +TD LLV AP Y E+G
Sbjct: 489 VFELQKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFY--HVHGEEG 546
Query: 525 KVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLD 584
+VYVY L++ + SL I H T ARFG A+AA+ DL+ D
Sbjct: 547 RVYVYRLSEQ--DGSFSLARILS------GHPGFT--------NARFGFAMAAMGDLSQD 590
Query: 585 GFNDIVIGAPLED---DHG---GAVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIH 638
D+ IGAPLE D G G+VYIY+G + +QRI + L++FG S+
Sbjct: 591 KLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMA 650
Query: 639 GEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCI 698
G D++GDGL D+T+G LG A +F SR V +KV+M F P+ + I +
Sbjct: 651 GGFDISGDGLADITVGTLGQAVVFRSRPVVRLKVSMAFTPSALPIGFNG---------VV 701
Query: 699 NATVCFDVK--LKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQE-----RKVQRNITV 751
N +CF++ + E + EA L + + +D +Q R S + R+ +
Sbjct: 702 NVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQL 761
Query: 752 RKSECTKHSFYMLDKHDFQDSVRITLDFNLTDPEN-----GPVLDDSLPNSVHEYIPFAK 806
+ + L + D + + + + L PE P+LD +P+ K
Sbjct: 762 CEDLLLMPTEGELCEEDCFSNASVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEK 821
Query: 807 DCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLV 866
C NK C+++L L ++++L++ ++ N++LT N+ + +Y T ++Y NL
Sbjct: 822 ACKNKLFCVAELQLATTVSQQELVVGLTKELTLNINLT--NSGEDSYMTSMALNYPRNLQ 879
Query: 867 FSGIEA-----IQKDSCESNHNI---TCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTI 918
++ IQ D + ++ C++G+P L+R + ++ I
Sbjct: 880 LKRMQKPPSPNIQCDDPQPVASVLIMNCRIGHPVLKRSSAHVSVVWQLEENAFPNRTADI 939
Query: 919 YLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVPEVINSTED 978
++ T+ +E ++ N + +++ G +++ + ++ +N+ +
Sbjct: 940 TVTVTNSNER------RSLANETHTLQFRHGF----------VAVLSKPSI-MYVNTGQG 982
Query: 979 IGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDP 1038
+ + + + F E +L I P G V+ L+ ++ + E
Sbjct: 983 LSHHKEFLFHVHGENLFG-AEYQLQICVPTKL-RGLQVVAVKKLTRTQASTVCTWSQERA 1040
Query: 1039 FSINSGKKMTTSTDHLKRGTILDC-------NTCKFATITCNLTSSDISQVNVSLILWKP 1091
+ +S H++ + C N A I+ + + + V IL +
Sbjct: 1041 CAY-------SSVQHVEEWHSVSCVIASDKENVTVAAEISWDHSEELLKDVTELQILGEI 1093
Query: 1092 TFIKSYFSSLNLTIRGELRSENASLVLSSSNQKRELAIQISKDGLPGRVPLWVILLSAFA 1151
+F KS + LN + N + ++ + KD +P +I+ +
Sbjct: 1094 SFNKSLYEGLN-----------------AENHRTKITVVFLKDEKYHSLP--IIIKGSVG 1134
Query: 1152 GLLLLMLLILALWKIGFFKR 1171
GLL+L+++++ L+K GFFKR
Sbjct: 1135 GLLVLIVILVILFKCGFFKR 1154
>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
Length = 1035
Score = 246 bits (627), Expect = 1e-64
Identities = 237/861 (27%), Positives = 380/861 (44%), Gaps = 100/861 (11%)
Query: 379 QTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGY 438
Q G + ++++ V++GA G++ W GT+ + + NT + +YLGY
Sbjct: 195 QAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTD-----NTYLKLNDEVIMNRRYTYLGY 249
Query: 439 TVNSATASSGDVL-YIAGQPRYNHTGQVIIYRMEDGN---IKILQTLSGEQIGSYFGSIL 494
V + S + + G P+ G+V I+R + + IKI Q SG+++GSYFGS L
Sbjct: 250 AVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQA-SGKKMGSYFGSSL 308
Query: 495 TTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQ 554
D++ D +D LLVGAPM+ E Q VY+ N E Q++L
Sbjct: 309 CAVDLNGDGLSD-LLVGAPMFSEIRDEGQVTVYINRGNGA-LEEQLAL------------ 354
Query: 555 HNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIR 614
+ A FG +IA++ DL+ DGF D+ IGAP EDD GAVYIYHG I
Sbjct: 355 -------TGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIV 407
Query: 615 KEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGL--GGAALFWSRDVAVVKV 672
+Y+ ++ L+ FGQSI G +D++G+G DVT+G L +R V V V
Sbjct: 408 PQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDV 467
Query: 673 TMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEADLQYRVTLDSLR-- 730
++ F P +NI CH + C+N T CF K E L Y + D +
Sbjct: 468 SI-FLPGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPG---EIGLNYVLMADVAKKE 523
Query: 731 --QISRSFF--SGTQERKVQRNITVRKSECTKHSFYMLDKHDFQD-------------SV 773
Q+ R +F G +V + + E T + K QD S
Sbjct: 524 KGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSE 583
Query: 774 RITLDFNLTDPENGPVLDDSLPNSVHE--YIPFAKDCGNKEKCISDLSLH-----VATTE 826
+T + P PVL + + F ++C E C +DL L + E
Sbjct: 584 HVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNC-RSEDCAADLQLQGKLLLSSMDE 642
Query: 827 KDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD----SCE--S 880
K L + ++++++ N D AY+ + S L F I QK+ SCE
Sbjct: 643 KTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFF--INMWQKEEMGISCELLE 700
Query: 881 NHNITCKVGYPFLRRGEMVTFKILFQFNTSYLM---ENVTIYLSATSDSEEPPETLSDNV 937
+ + C VG+PF+R F ++ F+TS+L E ++ ++A S + E E+L DN
Sbjct: 701 SDFLKCSVGFPFMRSKSKYEFSVI--FDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNT 758
Query: 938 VNISIPVKYEVGLQFYSSASE----YHISIAANETVPEVINSTEDIGNEINIFYLIRKSG 993
+ + +P+ +EV S Y S+ A + ++ E INI + +G
Sbjct: 759 LVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQ--LDDLECHFQPINITLQVYNTG 816
Query: 994 SFPMPELKLSISFPNMTSNGYPVLYPTG--LSSSENANCRPHIFEDPFSINSGKK---MT 1048
+P +SISFPN S+G ++ + E NC P I ++ T
Sbjct: 817 PSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFHT 876
Query: 1049 TSTDHLKRG-TILDCNTCKFATIT--CN---LTSSDISQVNVSLILWKPTFIKSYFSSLN 1102
K G +LDC + +T CN L + +++ ++L K S +
Sbjct: 877 IFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQ 936
Query: 1103 LTIRGELRSENASLVLSSSNQKRELAIQISKDGL-----PGRVPLWVILLSAFAGLLLLM 1157
R +++ + A V+ ++ E + + + L G V W+I +S G+L+ +
Sbjct: 937 FMSRAKVKVDPALRVVEIAHGNPE-EVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFL 995
Query: 1158 LLILALWKIGFFKRPLKKKME 1178
LL + LWK+GFF+R K+ +E
Sbjct: 996 LLAVLLWKMGFFRRRYKEIIE 1016
Score = 50.8 bits (120), Expect = 7e-06
Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 15/127 (11%)
Query: 28 SFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRT----GDVYKCP 83
++N+D + + F GP + FGY V ++ ++ +WVL+G+P + + G V+KC
Sbjct: 29 AYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVLVGAPKADSKYSPSVKSPGAVFKCR 88
Query: 84 VGRGESLPCVKLDLPVNTSI-----PNVTEVKENMTFGSTLVTNP--NGGFLACGPLYAY 136
V C +LD+ + E +++ G +L P +G LAC A+
Sbjct: 89 VHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSLARQPKADGRVLAC----AH 144
Query: 137 RCGHLHY 143
R +++Y
Sbjct: 145 RWKNIYY 151
>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
Length = 1032
Score = 233 bits (593), Expect = 1e-60
Identities = 225/857 (26%), Positives = 380/857 (44%), Gaps = 96/857 (11%)
Query: 379 QTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNE-PLASYLG 437
Q G S+ Y++D +++GA G+ W G++ + + + K+N+ SYLG
Sbjct: 199 QAGISSFYTKDLIVMGAPGSSYWTGSLFVYNIT------TNKYKAFLDKQNQVKFGSYLG 252
Query: 438 YTVNSATASSGDVL-YIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTT 496
Y+V + S + G P++ G+ I+ +++ + IL + G+++GSYFG+ +
Sbjct: 253 YSVGAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEMKGKKLGSYFGASVCA 312
Query: 497 TDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHN 556
D++ D +D LLVGAPM + E+G+V+VY +N ++E
Sbjct: 313 VDLNADGFSD-LLVGAPMQ--STIREEGRVFVY-INSGSGAVMNAME------------- 355
Query: 557 SCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKE 616
T ++ ARFG +I + D++ DGF D+ IGAP EDD GA+YIY+G I
Sbjct: 356 --TNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISST 413
Query: 617 YAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGL--GGAALFWSRDVAVVKVTM 674
++QRI K+L FGQSI G++D + +G DV +G A L +R V +V ++
Sbjct: 414 FSQRIEGLQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASL 473
Query: 675 NFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEADLQYRVTLDSLRQIS- 733
+ P VN K +C G +VCI+ T+CF K K I L Y ++LD R+
Sbjct: 474 S-HPESVNRTKFDCVENGWPSVCIDLTLCFSYKGKEVPGYIV---LFYNMSLDVNRKAES 529
Query: 734 --RSFFSGTQERKV---QRNITVRKSECTKHSFYM-LDKHDFQDSVRITLDFNLTD---- 783
R +FS V ++ R++ C H +M D D ++I ++L
Sbjct: 530 PPRFYFSSNGTSDVITGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVIS 589
Query: 784 -------PENGPVLDDSLPNSV-HEYIPFAKDCGNKEKCISDLSLHVAT------TEKDL 829
P P+L + + I FA+ C + E C +DL + K
Sbjct: 590 KRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAH-ENCSADLQVSAKIGFLKPHENKTY 648
Query: 830 LIVRSQND-KFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD--SCESNHN--- 883
L V S NVSL N D AY T V L F I +++ +CE N
Sbjct: 649 LAVGSMKTLMLNVSLF--NAGDDAYETTLHVKLPVGLYFIKILELEEKQINCEVTDNSGV 706
Query: 884 --ITCKVGYPFLRRGEMVTFKILFQFNT-SYLMENVTIYLSATSDSEEPPETLSDNVVNI 940
+ C +GY ++ + L ++ S E+++I + AT ++EE + L + V +
Sbjct: 707 VQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTV 766
Query: 941 SIPVKYEVGLQFYSSASEYHISIAAN-ETVPEVINSTEDIGNEINIFYLIRKSGSFPMPE 999
+IP+KYEV L + + +N E PE + ++N+ + + +G+ P
Sbjct: 767 AIPLKYEVKLTVHGFVNPTSFVYGSNDENEPETC-----MVEKMNLTFHVINTGNSMAPN 821
Query: 1000 LKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGK----------KMTT 1049
+ + I PN S L+ + C ++ ++ K + +
Sbjct: 822 VSVEIMVPNSFSPQTDKLFNILDVQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLS 881
Query: 1050 STD-HLKRGTILDCNTCKFATITCNLTSSDISQVNVSLILWKPTFIK-SYFSSLNLTIRG 1107
TD L D + F + S + V++ L +P+ ++ S+L IR
Sbjct: 882 KTDKRLLYCIKADPHCLNFLCNFGKMESGKEASVHIQL-EGRPSILEMDETSALKFEIRA 940
Query: 1108 ELRSENASLVLSSSNQKRELAIQISKDGLPGRVP-----LWVILLSAFAGLLLLMLLILA 1162
E V+ + K E + +GL + P + +I S GL++L+L+
Sbjct: 941 TGFPEPNPRVIELN--KDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYV 998
Query: 1163 LWKIGFFKRPLKKKMEK 1179
+WK GFFKR K +++
Sbjct: 999 MWKAGFFKRQYKSILQE 1015
Score = 63.9 bits (154), Expect = 8e-10
Identities = 51/183 (27%), Positives = 79/183 (43%), Gaps = 21/183 (11%)
Query: 1 MAPRPRARPGVAVACCWLLTVVLRCCVS------FNVDVKNSMTFSGPVEDMFGYTVQQY 54
MA R PG A TV+L C+ +NVD ++++ + GP +FGY+V +
Sbjct: 1 MAWEARREPGPRRAAV-RETVMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLH 59
Query: 55 ENEEGKWVLIGSPLVGQPKNRT----GDVYKCPVGRGESLPCVKLDLPVNTSIP---NVT 107
+ +W+L+G+P N + G +Y+C +G+ C +L L P
Sbjct: 60 SHGANRWLLVGAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQLGSPNGEPCGKTCL 119
Query: 108 EVKENMTFGSTLVTNP--NGGFLACGPLYA---YRCGHLHYTTGICSDVSPTF--QVVNS 160
E ++N G TL P NG + CG + Y TG C V P ++
Sbjct: 120 EERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFYIKNENKLPTGGCYGVPPDLRTELSKR 179
Query: 161 IAP 163
IAP
Sbjct: 180 IAP 182
>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
Length = 1051
Score = 233 bits (593), Expect = 1e-60
Identities = 225/871 (25%), Positives = 369/871 (42%), Gaps = 115/871 (13%)
Query: 374 EMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLA 433
E M Q G S ++Q+ V GA GAY+W G S +I + + S K E
Sbjct: 193 ETGMCQLGTSGGFTQNTVYFGAPGAYNWKGN------SYMIQRKEWDLSEYSYKDPEDQG 246
Query: 434 S-YLGYT--VNSATASSGDVLYIAGQPRYNHTGQVIIYRME-DGNIKILQTLSGEQIGSY 489
+ Y+GYT V S ++ + G PR+ H G V + E G+++ Q L G Q+G+Y
Sbjct: 247 NLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAY 306
Query: 490 FGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTC 549
FGS + D++ D D LLVGAP Y ++E G +YV+ + Q
Sbjct: 307 FGSAIALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVF---------------MNQAG 350
Query: 550 CSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGS 609
S H S P G+ FG ++A++ D+N DGF DI +GAP E G VYIYH S
Sbjct: 351 TSFPAHPSLLLHG---PSGSAFGLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSS 405
Query: 610 GKTIRKEYAQRIPSGGDG-KTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVA 668
K + ++ Q I G L FG S+ G+MD++ + D+ +G L +
Sbjct: 406 SKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPV 465
Query: 669 VVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEAD--LQYRVTL 726
+ V P + C T C+ +CF +S + Y + L Y +
Sbjct: 466 INIVHKTLVPRPAVLDPALC----TATSCVQVELCFAYN-QSAGNPNYRRNITLAYTLEA 520
Query: 727 DSLRQISRSFFSGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVR---ITLDFNL-- 781
D R+ R F+G++ ++ + C K ++D + +D +R I+++++L
Sbjct: 521 DRDRRPPRLRFAGSESAVFHGFFSMPEMRCQKLELLLMD--NLRDKLRPIIISMNYSLPL 578
Query: 782 ---TDPENG-------PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVA-TTEKDLL 830
P G P+L+ + H + F K+CG KC S+L + A +E+
Sbjct: 579 RMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQK 638
Query: 831 IVRSQND----KFNVSLTVKNTKDS------AYNTRTIVHYSPNLVFSGIEAIQKDSCES 880
+ R Q K +S+ V NT+ S A+ + P L+ S + +C++
Sbjct: 639 LSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPALLLSSVR--PPGACQA 696
Query: 881 NHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNI 940
N I C++G PF R M + ++ + L ++ S + DN+ +
Sbjct: 697 NETIFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQ------DNLWPM 750
Query: 941 SIPVKYEVGLQFYSSASEYHISIAANETV--PEVINSTEDIGNEINIFYLIRKSGS--FP 996
+ + + LQ S + + TV + + ED+G+ + + + G
Sbjct: 751 ILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVG 810
Query: 997 MPELKLSISFPNMTSNGYPVLYPTGLSSSENAN--CRPH---------IFEDPFSINSGK 1045
+ L L + +P SNG +LYPT ++ N + CRP DP S
Sbjct: 811 LGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSP 870
Query: 1046 K-----------------MTTSTDHLKRGTILDCNTCKFATITCNLTSSD---ISQVNVS 1085
+ + K T+L C T + + D ++ V V
Sbjct: 871 QRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAPVVTNVTVK 930
Query: 1086 LILWKPTFIKSY--FSSLNLTIRGELRSENASLVLSSSNQKRELAIQISK---DGLPGRV 1140
+W TFI+ Y F + + L + ++ N+ ++ I + LP +
Sbjct: 931 ARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPAEI 990
Query: 1141 PLWVILLSAFAGLLLLMLLILALWKIGFFKR 1171
LW++L++ AGLLLL L+IL LWK GFFKR
Sbjct: 991 ELWLVLVAVGAGLLLLGLIILLLWKCGFFKR 1021
Score = 39.7 bits (91), Expect = 0.017
Identities = 42/147 (28%), Positives = 67/147 (45%), Gaps = 16/147 (10%)
Query: 1 MAPRPRARPGVA--VACCWLLTVVLRCCV--SFNVDVKNSMTF-SGPVEDMFGYTV---Q 52
M P P P + C L V CV +FN+D + + +G +FGY+V +
Sbjct: 1 MGPGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHR 60
Query: 53 QYENEEGKWVLIGSPL-VGQPK---NRTGDVYKCPVGRGESLPCVKLDLPVNTSIPNVTE 108
Q E ++ +L G+P + P NRTG VY CP+ + C ++++ V +
Sbjct: 61 QTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKD-DCERMNITVKNDPGH--H 117
Query: 109 VKENMTFGSTLVT-NPNGGFLACGPLY 134
+ E+M G T+ + P G L C Y
Sbjct: 118 IIEDMWLGVTVASQGPAGRVLVCAHRY 144
>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
Length = 1066
Score = 230 bits (586), Expect = 7e-60
Identities = 224/871 (25%), Positives = 368/871 (42%), Gaps = 115/871 (13%)
Query: 374 EMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLA 433
E M Q G S ++Q+ V GA GAY+W G S +I + + S K E
Sbjct: 193 ETGMCQLGTSGGFTQNTVYFGAPGAYNWKGN------SYMIQRKEWDLSEYSYKDPEDQG 246
Query: 434 S-YLGYT--VNSATASSGDVLYIAGQPRYNHTGQVIIYRME-DGNIKILQTLSGEQIGSY 489
+ Y+GYT V S ++ + G PR+ H G V + E G+++ Q L G Q+G+Y
Sbjct: 247 NLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQVGAY 306
Query: 490 FGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTC 549
FGS + D++ D D LLVGAP Y ++E G +YV+ + Q
Sbjct: 307 FGSAIALADLNNDGWQD-LLVGAPYYFERKEEVGGAIYVF---------------MNQAG 350
Query: 550 CSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGS 609
S H S P G+ FG ++A++ D+N DGF DI +GAP E G VYIYH S
Sbjct: 351 TSFPAHPSLLLHG---PSGSAFGLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSS 405
Query: 610 GKTIRKEYAQRIPSGGDG-KTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVA 668
K + ++ Q I G L FG S+ G+MD++ + D+ +G L +
Sbjct: 406 SKGLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPV 465
Query: 669 VVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEAD--LQYRVTL 726
+ V P + C T C+ +CF +S + Y + L Y +
Sbjct: 466 INIVHKTLVPRPAVLDPALC----TATSCVQVELCFAYN-QSAGNPNYRRNITLAYTLEA 520
Query: 727 DSLRQISRSFFSGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVR---ITLDFNL-- 781
D R+ R F+G++ ++ + C K ++D + +D +R I+++++L
Sbjct: 521 DRDRRPPRLRFAGSESAVFHGFFSMPEMRCQKLELLLMD--NLRDKLRPIIISMNYSLPL 578
Query: 782 ---TDPENG-------PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVA-TTEKDLL 830
P G P+L+ + H + F K+CG KC S+L + A +E+
Sbjct: 579 RMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAFVSEQQQK 638
Query: 831 IVRSQND----KFNVSLTVKNTKDS------AYNTRTIVHYSPNLVFSGIEAIQKDSCES 880
+ R Q K +S+ V NT+ S A+ + P L+ S + +C++
Sbjct: 639 LSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPALLLSSVR--PPGACQA 696
Query: 881 NHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNI 940
N I C++G PF R M + ++ + L ++ S + DN+ +
Sbjct: 697 NETIFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQ------DNLWPM 750
Query: 941 SIPVKYEVGLQFYSSASEYHISIAANETV--PEVINSTEDIGNEINIFYLIRKSGS--FP 996
+ + + LQ S + + TV + + ED+G+ + + + G
Sbjct: 751 ILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPMGEGLVG 810
Query: 997 MPELKLSISFPNMTSNGYPVLYPTGLSSSENAN--CRPH---------IFEDPFSINSGK 1045
+ L L + +P SNG +LYPT ++ N + CRP DP S
Sbjct: 811 LGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWPCRPPGDLINPLNLTLSDPGDRPSSP 870
Query: 1046 K-----------------MTTSTDHLKRGTILDCNTCKFATITCNLTSSD---ISQVNVS 1085
+ + K T+L C T + + D ++ V V
Sbjct: 871 QRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWLECPIPDAPVVTNVTVK 930
Query: 1086 LILWKPTFIKSY--FSSLNLTIRGELRSENASLVLSSSNQKRELAIQISK---DGLPGRV 1140
+W TFI+ Y F + + L + ++ N+ ++ I + LP +
Sbjct: 931 ARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWFSVDIDSELVEELPAEI 990
Query: 1141 PLWVILLSAFAGLLLLMLLILALWKIGFFKR 1171
LW++L++ AGLLLL L+IL LWK FFKR
Sbjct: 991 ELWLVLVAVGAGLLLLGLIILLLWKCDFFKR 1021
Score = 39.7 bits (91), Expect = 0.017
Identities = 42/147 (28%), Positives = 67/147 (45%), Gaps = 16/147 (10%)
Query: 1 MAPRPRARPGVA--VACCWLLTVVLRCCV--SFNVDVKNSMTF-SGPVEDMFGYTV---Q 52
M P P P + C L V CV +FN+D + + +G +FGY+V +
Sbjct: 1 MGPGPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHR 60
Query: 53 QYENEEGKWVLIGSPL-VGQPK---NRTGDVYKCPVGRGESLPCVKLDLPVNTSIPNVTE 108
Q E ++ +L G+P + P NRTG VY CP+ + C ++++ V +
Sbjct: 61 QTERQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKD-DCERMNITVKNDPGH--H 117
Query: 109 VKENMTFGSTLVT-NPNGGFLACGPLY 134
+ E+M G T+ + P G L C Y
Sbjct: 118 IIEDMWLGVTVASQGPAGRVLVCAHRY 144
>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
Length = 1044
Score = 227 bits (578), Expect = 6e-59
Identities = 242/914 (26%), Positives = 399/914 (43%), Gaps = 161/914 (17%)
Query: 379 QTGFSAHYSQD--WVMLGAVGAYDWNGTVVMQKASQ----IIIPRNTTFNVESTKKNEPL 432
Q G +A +S D +++ GA G Y+W GT ++ +Q + + + K+ +P
Sbjct: 101 QQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPR 160
Query: 433 A------SYLGYTVNSATA--SSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQT-LSG 483
SY G++++S + ++ ++AG PR NH G V+I R + + + + LSG
Sbjct: 161 LIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSG 220
Query: 484 EQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLE 543
E++ S FG L D++ D D L+VGAP + ++E G VYVY LNQ + +
Sbjct: 221 ERLTSGFGYSLAVADLNSDGWPD-LIVGAPYFFERQEELGGAVYVY-LNQGG--HWAGIS 276
Query: 544 PIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAV 603
P++ C S + FG ++A + DLN DGF DI +GAP + D G V
Sbjct: 277 PLR--LCGSPD--------------SMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKV 318
Query: 604 YIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAA-LF 662
+IYHGS + + +Q + G+ +K FG S+ G +D++G+ D+ +G L A LF
Sbjct: 319 FIYHGSSLGVVAKPSQVLE--GEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLF 376
Query: 663 WSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFD-VKLKSKE------DTI 715
+R + V ++ P +++++ NC G +VC++ VCF + + S D +
Sbjct: 377 RARPILHVSHEVSIAPRSIDLEQPNC--AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYV 434
Query: 716 YEADLQYRVTLDSLRQISRSFF--SGTQERKVQRNITV-----RKSECTKHSFYMLDK-H 767
+AD R+ Q+ R F +E K Q + TV C F + +
Sbjct: 435 LDADTDRRLR----GQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVK 490
Query: 768 DFQDSVRITLDFNLTDPEN------------GPVLDDSLPNSVHEYIPFAKD-CGNKEKC 814
D ++ +TL ++L P P+L+ P++ I F K CG + C
Sbjct: 491 DKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKIC 550
Query: 815 ISDLSL-------HVATTE----------KDLLIVRSQNDKFNVSLTVKNTK-------- 849
S+L L V+ TE L S + L V N
Sbjct: 551 QSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQA 610
Query: 850 --DSAYNTRTIVHYSPNLVFSGIEAI---QKDSCESNHN---ITCKVGYPFLRRGEMVTF 901
D A+ + +V +L +SG+ A+ +K C SN N + C++G P ++RG VTF
Sbjct: 611 DGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNP-MKRGAQVTF 669
Query: 902 KILFQ-----FNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSA 956
++ T+ L V + L+ S+ E P V+ V E+ L A
Sbjct: 670 YLILSTSGISIETTEL--EVELLLATISEQELHP-------VSARARVFIELPLSIAGMA 720
Query: 957 SEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSF--PMPELKLSISFPNMTSNGY 1014
+ + + S D+G+++ + G + L+I +P+ +NG
Sbjct: 721 IPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGK 780
Query: 1015 PVLYPT------GLSSSENANC--RPHIF--------------EDPFSINSGKKMT---- 1048
+LYP G + C RP+I E P G++
Sbjct: 781 WLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMS 840
Query: 1049 ---TSTDHLKRGTILDC--NTCKFATITCNLTSSDISQV-NVSLILWKPTFIKSYFS--S 1100
S+ K+ LDC T +C L S D + V +V LW TF++ Y + S
Sbjct: 841 WWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKS 900
Query: 1101 LNLTIRGELRSENASLVLSSSNQKRELAIQISKDGLP---GRVPLWVILLSAFAGLLLLM 1157
L + +R + +++ L + + + + D + VP WVILL+ AGLL+L
Sbjct: 901 LEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLA 960
Query: 1158 LLILALWKIGFFKR 1171
LL+L LWK+GFFKR
Sbjct: 961 LLVLLLWKMGFFKR 974
>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 1141
Score = 227 bits (578), Expect = 6e-59
Identities = 242/914 (26%), Positives = 399/914 (43%), Gaps = 161/914 (17%)
Query: 379 QTGFSAHYSQD--WVMLGAVGAYDWNGTVVMQKASQ----IIIPRNTTFNVESTKKNEPL 432
Q G +A +S D +++ GA G Y+W GT ++ +Q + + + K+ +P
Sbjct: 198 QQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPR 257
Query: 433 A------SYLGYTVNSATA--SSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQT-LSG 483
SY G++++S + ++ ++AG PR NH G V+I R + + + + LSG
Sbjct: 258 LIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSG 317
Query: 484 EQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLE 543
E++ S FG L D++ D D L+VGAP + ++E G VYVY LNQ + +
Sbjct: 318 ERLTSGFGYSLAVADLNSDGWPD-LIVGAPYFFERQEELGGAVYVY-LNQGG--HWAGIS 373
Query: 544 PIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAV 603
P++ C S + FG ++A + DLN DGF DI +GAP + D G V
Sbjct: 374 PLR--LCGSPD--------------SMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKV 415
Query: 604 YIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAA-LF 662
+IYHGS + + +Q + G+ +K FG S+ G +D++G+ D+ +G L A LF
Sbjct: 416 FIYHGSSLGVVAKPSQVLE--GEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLF 473
Query: 663 WSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFD-VKLKSKE------DTI 715
+R + V ++ P +++++ NC G +VC++ VCF + + S D +
Sbjct: 474 RARPILHVSHEVSIAPRSIDLEQPNC--AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYV 531
Query: 716 YEADLQYRVTLDSLRQISRSFF--SGTQERKVQRNITV-----RKSECTKHSFYMLDK-H 767
+AD R+ Q+ R F +E K Q + TV C F + +
Sbjct: 532 LDADTDRRLR----GQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVK 587
Query: 768 DFQDSVRITLDFNLTDPEN------------GPVLDDSLPNSVHEYIPFAKD-CGNKEKC 814
D ++ +TL ++L P P+L+ P++ I F K CG + C
Sbjct: 588 DKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKIC 647
Query: 815 ISDLSL-------HVATTE----------KDLLIVRSQNDKFNVSLTVKNTK-------- 849
S+L L V+ TE L S + L V N
Sbjct: 648 QSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQA 707
Query: 850 --DSAYNTRTIVHYSPNLVFSGIEAI---QKDSCESNHN---ITCKVGYPFLRRGEMVTF 901
D A+ + +V +L +SG+ A+ +K C SN N + C++G P ++RG VTF
Sbjct: 708 DGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNP-MKRGAQVTF 766
Query: 902 KILFQ-----FNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSA 956
++ T+ L V + L+ S+ E P V+ V E+ L A
Sbjct: 767 YLILSTSGISIETTEL--EVELLLATISEQELHP-------VSARARVFIELPLSIAGMA 817
Query: 957 SEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSF--PMPELKLSISFPNMTSNGY 1014
+ + + S D+G+++ + G + L+I +P+ +NG
Sbjct: 818 IPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGK 877
Query: 1015 PVLYPT------GLSSSENANC--RPHIF--------------EDPFSINSGKKMT---- 1048
+LYP G + C RP+I E P G++
Sbjct: 878 WLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMS 937
Query: 1049 ---TSTDHLKRGTILDC--NTCKFATITCNLTSSDISQV-NVSLILWKPTFIKSYFS--S 1100
S+ K+ LDC T +C L S D + V +V LW TF++ Y + S
Sbjct: 938 WWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKS 997
Query: 1101 LNLTIRGELRSENASLVLSSSNQKRELAIQISKDGLP---GRVPLWVILLSAFAGLLLLM 1157
L + +R + +++ L + + + + D + VP WVILL+ AGLL+L
Sbjct: 998 LEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLA 1057
Query: 1158 LLILALWKIGFFKR 1171
LL+L LWK+GFFKR
Sbjct: 1058 LLVLLLWKMGFFKR 1071
Score = 57.4 bits (137), Expect = 8e-08
Identities = 38/128 (29%), Positives = 61/128 (47%), Gaps = 11/128 (8%)
Query: 18 LLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTV---QQYENEEGKWVLIGSP----LVG 70
L+ ++ V+FN+DV ++ G +FG++V +Q + W+L+G+P L G
Sbjct: 23 LVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPG 82
Query: 71 QPKNRTGDVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFG-STLVTNPNGGFLA 129
Q NRTG ++ CP+ E C ++D+ + E KEN G S P G +
Sbjct: 83 QQANRTGGLFACPLSL-EETDCYRVDIDQGADMQK--ESKENQWLGVSVRSQGPGGKIVT 139
Query: 130 CGPLYAYR 137
C Y R
Sbjct: 140 CAHRYEAR 147
>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
Length = 1137
Score = 224 bits (572), Expect = 3e-58
Identities = 242/911 (26%), Positives = 394/911 (43%), Gaps = 159/911 (17%)
Query: 379 QTGFSAHYSQD--WVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEP----- 431
Q G +A +S D +++ GA G Y+W G + + P + P
Sbjct: 198 QQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSD-PDQLVYKTLDPADRLPGPAGD 256
Query: 432 --LASYLGYTVNSATA--SSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQT-LSGEQI 486
L SYLG++++S + ++ ++AG PR NH G V+I R + + + + LSGE++
Sbjct: 257 LALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERL 316
Query: 487 GSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIK 546
S FG L D++ D D L+VGAP + ++E G VYVY LNQ + + P++
Sbjct: 317 TSGFGYSLAVADLNSDGWPD-LIVGAPYFFERQEELGGAVYVY-LNQGG--HWAGISPLR 372
Query: 547 QTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIY 606
C S + FG ++A + DLN DGF DI +GAP + D G V+IY
Sbjct: 373 --LCGSPD--------------SMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIY 414
Query: 607 HGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAA-LFWSR 665
HGS + + +Q + G+ +K FG S+ G +D++G+ D+ +G L A LF +R
Sbjct: 415 HGSSLGVVAKPSQVLE--GEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRAR 472
Query: 666 DVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFD-VKLKSKE------DTIYEA 718
+ V ++ P +++++ NC G +VC++ VCF + + S D + +A
Sbjct: 473 PILHVSHEVSIAPRSIDLEQPNC--AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDA 530
Query: 719 DLQYRVTLDSLRQISRSFF--SGTQERKVQRNITV-----RKSECTKHSFYMLDK-HDFQ 770
D R+ Q+ R F +E K Q + TV C F + + D
Sbjct: 531 DTDRRLR----GQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKL 586
Query: 771 DSVRITLDFNLTDPEN------------GPVLDDSLPNSVHEYIPFAKD-CGNKEKCISD 817
++ +TL ++L P P+L+ P++ I F K CG + C S+
Sbjct: 587 RAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSN 646
Query: 818 LSL-------HVATTE----------KDLLIVRSQNDKFNVSLTVKNTK----------D 850
L L V+ TE L S + L V N D
Sbjct: 647 LQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGD 706
Query: 851 SAYNTRTIVHYSPNLVFSGIEAI---QKDSCESNHN---ITCKVGYPFLRRGEMVTFKIL 904
A+ + +V +L +SG+ A+ +K C SN N + C++G P ++RG VTF ++
Sbjct: 707 DAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNP-MKRGAQVTFYLI 765
Query: 905 FQ-----FNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEY 959
T+ L V + L+ S+ E P V+ V E+ L A
Sbjct: 766 LSTSGISIETTEL--EVELLLATISEQELHP-------VSARARVFIELPLSIAGMAIPQ 816
Query: 960 HISIAANETVPEVINSTEDIGNEINIFYLIRKSGSF--PMPELKLSISFPNMTSNGYPVL 1017
+ + + S D+G+++ + G + L+I +P+ +NG +L
Sbjct: 817 QLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLL 876
Query: 1018 YPT------GLSSSENANC--RPHIF--------------EDPFSINSGKKMT------- 1048
YP G + C RP+I E P G++
Sbjct: 877 YPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWP 936
Query: 1049 TSTDHLKRGTILDC--NTCKFATITCNLTSSDISQV-NVSLILWKPTFIKSYFS--SLNL 1103
S+ K+ LDC T +C L S D + V +V LW TF++ Y + SL +
Sbjct: 937 VSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEV 996
Query: 1104 TIRGELRSENASLVLSSSNQKRELAIQISKDGLP---GRVPLWVILLSAFAGLLLLMLLI 1160
+R + +++ L + + + + D + VP WVILL+ AGLL+L LL+
Sbjct: 997 IVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLV 1056
Query: 1161 LALWKIGFFKR 1171
L LWK+GFFKR
Sbjct: 1057 LLLWKMGFFKR 1067
Score = 57.4 bits (137), Expect = 8e-08
Identities = 38/128 (29%), Positives = 61/128 (47%), Gaps = 11/128 (8%)
Query: 18 LLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTV---QQYENEEGKWVLIGSP----LVG 70
L+ ++ V+FN+DV ++ G +FG++V +Q + W+L+G+P L G
Sbjct: 23 LVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPG 82
Query: 71 QPKNRTGDVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFG-STLVTNPNGGFLA 129
Q NRTG ++ CP+ E C ++D+ + E KEN G S P G +
Sbjct: 83 QQANRTGGLFACPLSL-EETDCYRVDIDQGADMQK--ESKENQWLGVSVRSQGPGGKIVT 139
Query: 130 CGPLYAYR 137
C Y R
Sbjct: 140 CAHRYEAR 147
>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo
sapiens]
Length = 1073
Score = 218 bits (554), Expect = 4e-56
Identities = 213/898 (23%), Positives = 389/898 (43%), Gaps = 141/898 (15%)
Query: 379 QTGFSAHYSQD--WVMLGAVGAYDWNGTVVMQKASQIIIPRNT----TFNVESTKKNE-- 430
Q G +A +++D +++ GA G Y+W G V +++ + N + V +++
Sbjct: 189 QQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDES 248
Query: 431 ----PLASYLGYTVNSATA--SSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKIL--QTLS 482
P SYLG++++S S ++ +++G PR NH+G V++ + + + +L
Sbjct: 249 LVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFD 308
Query: 483 GEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSL 542
GE + S FG + D++KD DI+ +GAP Y + E G VYVY Q R+ ++
Sbjct: 309 GEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYMNQQGRWN---NV 364
Query: 543 EPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGA 602
+PI+ N + FG A+ + D+N DG+ DI +GAP +D G
Sbjct: 365 KPIRL----------------NGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDL--GK 406
Query: 603 VYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAA-L 661
V+IYHGS I + Q + +FG SI G MDL+ + DV +G L + +
Sbjct: 407 VFIYHGSANGINTKPTQVLKG-----ISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTI 461
Query: 662 FWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEADLQ 721
F SR V ++ T+ PN++++++K +C+ CF+ + Y +
Sbjct: 462 FRSRPVINIQKTITVTPNRIDLRQKTA-CGAPSGICLQVKSCFEY---TANPAGYNPSIS 517
Query: 722 YRVTLDSLRQISRSFFSGT-------QERKVQRNITVRKSE---CTKHSFYMLDK-HDFQ 770
TL++ ++ +S S E K + +T+++ + C + + ++ D D
Sbjct: 518 IVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKL 577
Query: 771 DSVRITLDFNLTDPENG----------PVLDDSLPNSVHEYIPFAKD-CGNKEKCISDLS 819
+ IT + +P + P+L+ P + H + F K+ CG+ C S+L
Sbjct: 578 RPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLK 637
Query: 820 LHVATTEKD----------------LLIVRSQNDKFNVSLTVKNTK----------DSAY 853
L ++ L+++ Q D + +TV N+ D A+
Sbjct: 638 LEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKD-IALEITVTNSPSNPRNPTKDGDDAH 696
Query: 854 NTRTIVHYSPNLVFSGIEAIQ-----KDSCESNHN---ITCKVGYPFLRRGEMVTFKILF 905
+ I + L +S ++ + SC +N N C++G PF R + + +L
Sbjct: 697 EAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLS 756
Query: 906 QFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAA 965
++ ++ I L + S + DN+ I+ K + L S +
Sbjct: 757 TTEVTFDTPDLDINLKLETTSNQ------DNLAPITAKAKVVIELLLSVSGVAKPSQVYF 810
Query: 966 NETV--PEVINSTEDIGNEINIFYLIRKSGSFPMPEL---KLSISFPNMTSNGYPVLYPT 1020
TV + + S +++G+ I + + G P+ L L+I +P SNG +LY
Sbjct: 811 GGTVVGEQAMKSEDEVGSLIEYEFRVINLGK-PLTNLGTATLNIQWPKEISNGKWLLYLV 869
Query: 1021 GLSSS--ENANCRPHIFEDPFSI----NSGKKMTTSTDHLKRGTILDCNT-CKFATITCN 1073
+ S E C P + ++ NS KK + + K+ T+ C+
Sbjct: 870 KVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCS 929
Query: 1074 LTSSDIS--------QVNVSLIL----WKPTFIKSY--FSSLNLTIRGELRSENASLVLS 1119
+ + ++ SLIL W TF++ Y + L++ +R + A+ +
Sbjct: 930 VNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIR 989
Query: 1120 SSNQKRELAIQISKDGLPGR---VPLWVILLSAFAGLLLLMLLILALWKIGFFKRPLK 1174
N ++ + + + VP W+IL++ AG+L+L LL+ LWK GFFKR K
Sbjct: 990 LPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNKK 1047
Score = 42.0 bits (97), Expect = 0.003
Identities = 37/125 (29%), Positives = 62/125 (49%), Gaps = 16/125 (12%)
Query: 24 RCCVSFNVDVK--NSMTFSGPVEDMFGYTVQ---QYENEEGKWVLIGSP----LVGQPKN 74
R +FN+D + N + G +FG+++ Q + E+ + +L+G+P L Q N
Sbjct: 19 RLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRAN 78
Query: 75 RTGDVYKCPV-GRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVT-NPNGGFLACGP 132
RTG +Y C + RG PC +++ N + P +E KE+ G T+ + P G + C
Sbjct: 79 RTGGLYSCDITARG---PCTRIEFD-NDADP-TSESKEDQWMGVTVQSQGPGGKVVTCAH 133
Query: 133 LYAYR 137
Y R
Sbjct: 134 RYEKR 138
>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo
sapiens]
Length = 1091
Score = 217 bits (553), Expect = 5e-56
Identities = 212/895 (23%), Positives = 388/895 (43%), Gaps = 141/895 (15%)
Query: 379 QTGFSAHYSQD--WVMLGAVGAYDWNGTVVMQKASQIIIPRNT----TFNVESTKKNE-- 430
Q G +A +++D +++ GA G Y+W G V +++ + N + V +++
Sbjct: 189 QQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDES 248
Query: 431 ----PLASYLGYTVNSATA--SSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKIL--QTLS 482
P SYLG++++S S ++ +++G PR NH+G V++ + + + +L
Sbjct: 249 LVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFD 308
Query: 483 GEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSL 542
GE + S FG + D++KD DI+ +GAP Y + E G VYVY Q R+ ++
Sbjct: 309 GEGLASSFGYDVAVVDLNKDGWQDIV-IGAPQYFDRDGEVGGAVYVYMNQQGRWN---NV 364
Query: 543 EPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGA 602
+PI+ N + FG A+ + D+N DG+ DI +GAP +D G
Sbjct: 365 KPIRL----------------NGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDL--GK 406
Query: 603 VYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAA-L 661
V+IYHGS I + Q + +FG SI G MDL+ + DV +G L + +
Sbjct: 407 VFIYHGSANGINTKPTQVLKG-----ISPYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTI 461
Query: 662 FWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEADLQ 721
F SR V ++ T+ PN++++++K +C+ CF+ + Y +
Sbjct: 462 FRSRPVINIQKTITVTPNRIDLRQKTA-CGAPSGICLQVKSCFEY---TANPAGYNPSIS 517
Query: 722 YRVTLDSLRQISRSFFSGT-------QERKVQRNITVRKSE---CTKHSFYMLDK-HDFQ 770
TL++ ++ +S S E K + +T+++ + C + + ++ D D
Sbjct: 518 IVGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKL 577
Query: 771 DSVRITLDFNLTDPENG----------PVLDDSLPNSVHEYIPFAKD-CGNKEKCISDLS 819
+ IT + +P + P+L+ P + H + F K+ CG+ C S+L
Sbjct: 578 RPIPITASVEIQEPSSRRRVNSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLK 637
Query: 820 LHVATTEKD----------------LLIVRSQNDKFNVSLTVKNTK----------DSAY 853
L ++ L+++ Q D + +TV N+ D A+
Sbjct: 638 LEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKD-IALEITVTNSPSNPRNPTKDGDDAH 696
Query: 854 NTRTIVHYSPNLVFSGIEAIQ-----KDSCESNHN---ITCKVGYPFLRRGEMVTFKILF 905
+ I + L +S ++ + SC +N N C++G PF R + + +L
Sbjct: 697 EAKLIATFPDTLTYSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLS 756
Query: 906 QFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAA 965
++ ++ I L + S + DN+ I+ K + L S +
Sbjct: 757 TTEVTFDTPDLDINLKLETTSNQ------DNLAPITAKAKVVIELLLSVSGVAKPSQVYF 810
Query: 966 NETV--PEVINSTEDIGNEINIFYLIRKSGSFPMPEL---KLSISFPNMTSNGYPVLYPT 1020
TV + + S +++G+ I + + G P+ L L+I +P SNG +LY
Sbjct: 811 GGTVVGEQAMKSEDEVGSLIEYEFRVINLGK-PLTNLGTATLNIQWPKEISNGKWLLYLV 869
Query: 1021 GLSSS--ENANCRPHIFEDPFSI----NSGKKMTTSTDHLKRGTILDCNT-CKFATITCN 1073
+ S E C P + ++ NS KK + + K+ T+ C+
Sbjct: 870 KVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCS 929
Query: 1074 LTSSDIS--------QVNVSLIL----WKPTFIKSY--FSSLNLTIRGELRSENASLVLS 1119
+ + ++ SLIL W TF++ Y + L++ +R + A+ +
Sbjct: 930 VNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIR 989
Query: 1120 SSNQKRELAIQISKDGLPGR---VPLWVILLSAFAGLLLLMLLILALWKIGFFKR 1171
N ++ + + + VP W+IL++ AG+L+L LL+ LWK GFFKR
Sbjct: 990 LPNAGTQVRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKR 1044
Score = 42.0 bits (97), Expect = 0.003
Identities = 37/125 (29%), Positives = 62/125 (49%), Gaps = 16/125 (12%)
Query: 24 RCCVSFNVDVK--NSMTFSGPVEDMFGYTVQ---QYENEEGKWVLIGSP----LVGQPKN 74
R +FN+D + N + G +FG+++ Q + E+ + +L+G+P L Q N
Sbjct: 19 RLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLLVGAPRAEALPLQRAN 78
Query: 75 RTGDVYKCPV-GRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVT-NPNGGFLACGP 132
RTG +Y C + RG PC +++ N + P +E KE+ G T+ + P G + C
Sbjct: 79 RTGGLYSCDITARG---PCTRIEFD-NDADP-TSESKEDQWMGVTVQSQGPGGKVVTCAH 133
Query: 133 LYAYR 137
Y R
Sbjct: 134 RYEKR 138
>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
Length = 1002
Score = 211 bits (537), Expect = 3e-54
Identities = 223/886 (25%), Positives = 381/886 (43%), Gaps = 123/886 (13%)
Query: 379 QTGFSAHYSQ-DWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLA---- 433
Q GFS +++ D V+LG G++ W G ++ + ++I+ + NV S K N LA
Sbjct: 140 QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDP--NVYSIKYNNQLATRTA 197
Query: 434 ------SYLGYTVNSATASSGDVL--YIAGQPRYNHT-GQVIIYRMEDG-NIKILQTLSG 483
SYLGY+V + +GD + +++G PR T G V IY DG N+ L +G
Sbjct: 198 QAIFDDSYLGYSV-AVGDFNGDGIDDFVSGVPRAARTLGMVYIY---DGKNMSSLYNFTG 253
Query: 484 EQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGT----EKEEQGKVYVYALNQTRFEYQ 539
EQ+ +YFG + TDI+ D D+ +GAP++M + +E G+V V +L + ++Q
Sbjct: 254 EQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSV-SLQRASGDFQ 311
Query: 540 MSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLE-DD 598
TT+ ARFG+AIA + DL+ DGFNDI I AP +D
Sbjct: 312 -------------------TTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGED 352
Query: 599 HGGAVYIYHGSGKTIRKEYAQRIPSGGDGKTLK-FFGQSIHGEMDLNGDGLTDVTIGGLG 657
G VYI++G + +Q + +++ FG S+ G D++ +G D+ +G G
Sbjct: 353 KKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFG 412
Query: 658 --GAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGK--ETVCINATVCFDVKLKSKED 713
A L+ +R V V + P+ +N K C + G + C N C +K K
Sbjct: 413 VDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFC--LKADGKGV 470
Query: 714 TIYEADLQYRVTLDSLRQ---ISRSFFSGTQERKVQRNITVRKS---ECTKHSFYMLDKH 767
+ + Q + LD L+Q I R+ F ++ +N+T+ + +C + Y+ D+
Sbjct: 471 LPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDES 530
Query: 768 DFQDSV-------RITLDFNLTDPENG--PVLDDSLPNSVHEYIPFAKDCGNKEKCISDL 818
+F+D + LD+ G P+L+ P ++ DCG C L
Sbjct: 531 EFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKL 590
Query: 819 SLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGI----EAIQ 874
+ V + +K + I ++ + + +N + AY IV F G+ EA+
Sbjct: 591 EVSVDSDQKKIYI--GDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALA 648
Query: 875 KDSC-----ESNHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEP 929
+ SC + C +G P ++ G + + F + M+ S D +
Sbjct: 649 RLSCAFKTENQTRQVVCDLGNP-MKAGTQLLAGLRFSVHQQSEMDT-----SVKFDLQIQ 702
Query: 930 PETLSDNV---VNISIPVKYEVGLQFYSSASEYHISIAA-NETVPEVINSTEDIGNEINI 985
L D V V+ + + ++ +S HI + N E + ED+G +
Sbjct: 703 SSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQH 762
Query: 986 FYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGK 1045
Y +R +G + L + +P +N +LY NC + +P I
Sbjct: 763 IYELRNNGPSSFSKAMLHLQWPYKYNNN-TLLYILHYDIDGPMNCTSDMEINPLRIKISS 821
Query: 1046 KMTTST----------DHL--------KRGTI--LDCNTCKFATITCNLTSSDISQ---V 1082
TT DHL G I L C + I C + D + +
Sbjct: 822 LQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAIL 881
Query: 1083 NVSLILWKPTFIKSYFSSLNLTIRG-------ELRSENASLVLSSSNQKRELAIQISKDG 1135
V +LW TF+ + + +++ E +N + +++ +
Sbjct: 882 YVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQP 941
Query: 1136 LPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFK--RPLKKKMEK 1179
P VP+WVI+L+ AGLLLL +L+ ++++GFFK RP +++ E+
Sbjct: 942 APMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQER 987
>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
Length = 1048
Score = 211 bits (537), Expect = 3e-54
Identities = 223/886 (25%), Positives = 381/886 (43%), Gaps = 123/886 (13%)
Query: 379 QTGFSAHYSQ-DWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLA---- 433
Q GFS +++ D V+LG G++ W G ++ + ++I+ + NV S K N LA
Sbjct: 186 QGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDP--NVYSIKYNNQLATRTA 243
Query: 434 ------SYLGYTVNSATASSGDVL--YIAGQPRYNHT-GQVIIYRMEDG-NIKILQTLSG 483
SYLGY+V + +GD + +++G PR T G V IY DG N+ L +G
Sbjct: 244 QAIFDDSYLGYSV-AVGDFNGDGIDDFVSGVPRAARTLGMVYIY---DGKNMSSLYNFTG 299
Query: 484 EQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGT----EKEEQGKVYVYALNQTRFEYQ 539
EQ+ +YFG + TDI+ D D+ +GAP++M + +E G+V V +L + ++Q
Sbjct: 300 EQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEVGQVSV-SLQRASGDFQ 357
Query: 540 MSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLE-DD 598
TT+ ARFG+AIA + DL+ DGFNDI I AP +D
Sbjct: 358 -------------------TTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGED 398
Query: 599 HGGAVYIYHGSGKTIRKEYAQRIPSGGDGKTLK-FFGQSIHGEMDLNGDGLTDVTIGGLG 657
G VYI++G + +Q + +++ FG S+ G D++ +G D+ +G G
Sbjct: 399 KKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFG 458
Query: 658 --GAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGK--ETVCINATVCFDVKLKSKED 713
A L+ +R V V + P+ +N K C + G + C N C +K K
Sbjct: 459 VDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFC--LKADGKGV 516
Query: 714 TIYEADLQYRVTLDSLRQ---ISRSFFSGTQERKVQRNITVRKS---ECTKHSFYMLDKH 767
+ + Q + LD L+Q I R+ F ++ +N+T+ + +C + Y+ D+
Sbjct: 517 LPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDES 576
Query: 768 DFQDSV-------RITLDFNLTDPENG--PVLDDSLPNSVHEYIPFAKDCGNKEKCISDL 818
+F+D + LD+ G P+L+ P ++ DCG C L
Sbjct: 577 EFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLDCGEDNVCKPKL 636
Query: 819 SLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGI----EAIQ 874
+ V + +K + I ++ + + +N + AY IV F G+ EA+
Sbjct: 637 EVSVDSDQKKIYI--GDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALA 694
Query: 875 KDSC-----ESNHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEP 929
+ SC + C +G P ++ G + + F + M+ S D +
Sbjct: 695 RLSCAFKTENQTRQVVCDLGNP-MKAGTQLLAGLRFSVHQQSEMDT-----SVKFDLQIQ 748
Query: 930 PETLSDNV---VNISIPVKYEVGLQFYSSASEYHISIAA-NETVPEVINSTEDIGNEINI 985
L D V V+ + + ++ +S HI + N E + ED+G +
Sbjct: 749 SSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENPETEEDVGPVVQH 808
Query: 986 FYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGK 1045
Y +R +G + L + +P +N +LY NC + +P I
Sbjct: 809 IYELRNNGPSSFSKAMLHLQWPYKYNNN-TLLYILHYDIDGPMNCTSDMEINPLRIKISS 867
Query: 1046 KMTTST----------DHL--------KRGTI--LDCNTCKFATITCNLTSSDISQ---V 1082
TT DHL G I L C + I C + D + +
Sbjct: 868 LQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAIL 927
Query: 1083 NVSLILWKPTFIKSYFSSLNLTIRG-------ELRSENASLVLSSSNQKRELAIQISKDG 1135
V +LW TF+ + + +++ E +N + +++ +
Sbjct: 928 YVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQP 987
Query: 1136 LPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFK--RPLKKKMEK 1179
P VP+WVI+L+ AGLLLL +L+ ++++GFFK RP +++ E+
Sbjct: 988 APMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQER 1033
Score = 49.3 bits (116), Expect = 2e-05
Identities = 42/145 (28%), Positives = 60/145 (41%), Gaps = 14/145 (9%)
Query: 3 PRPRARPGVAVACCWLLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWV 62
PR R R G L ++L C +FN+DV + +SGP FG+ V + +
Sbjct: 5 PRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRM 64
Query: 63 LIGSPLVGQPKNRT--------GDVYKCPVGRGESLPCVKLDLPVNTSI--PNVTEVKEN 112
+ LVG PK T G V KC ++ D N + E K +
Sbjct: 65 FL---LVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSH 121
Query: 113 MTFGSTLVTNPNGGFLACGPLYAYR 137
FG++ V + LAC PLY +R
Sbjct: 122 QWFGAS-VRSKQDKILACAPLYHWR 145
>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
Length = 1049
Score = 206 bits (523), Expect = 1e-52
Identities = 219/866 (25%), Positives = 374/866 (43%), Gaps = 98/866 (11%)
Query: 379 QTGFSAHYSQDW-VMLGAVGAYDWNGTVVMQKASQII---IPRNTTFNVESTKKNEPLAS 434
Q GFSA +++ V+LG G+Y W G ++ QI P V+ + +S
Sbjct: 206 QGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAESYYPEYLINLVQGQLQTRQASS 265
Query: 435 -----YLGYTVNSATASSGDVL-YIAGQPRYNHT-GQVIIYRMEDGNIKILQTLSGEQIG 487
YLGY+V S D ++AG P+ N T G V I D I+ L SGEQ+
Sbjct: 266 IYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGNLTYGYVTILNGSD--IRSLYNFSGEQMA 323
Query: 488 SYFGSILTTTDIDKDSNTDILLVGAPMYMGT----EKEEQGKVYVYALNQTRFEYQMSLE 543
SYFG + TD++ D D LLVGAP+ M +E G+VYVY ++ +E
Sbjct: 324 SYFGYAVAATDVNGDGLDD-LLVGAPLLMDRTPDGRPQEVGRVYVY------LQHPAGIE 376
Query: 544 PIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDD-HGGA 602
P + RFG+++ + DL+ DG+ND+ IGAP + G
Sbjct: 377 PTPTLTLTGHDEFG------------RFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGV 424
Query: 603 VYIYHGSGKTIRKEYAQRI-PSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLG--GA 659
V+++ G + + +Q + P T FFG ++ G DL+G+G D+ +G G A
Sbjct: 425 VFVFPGGPGGLGSKPSQVLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKA 484
Query: 660 ALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTI-YEA 718
++ R + ++ P N ++++C +EG CIN + C + K D+I +
Sbjct: 485 VVYRGRPIVSASASLTIFPAMFNPEERSCSLEGNPVACINLSFCLNASGKHVADSIGFTV 544
Query: 719 DLQYRVTLDSLRQ---ISRSFFSGTQERKVQRNITVR---KSECTKHSFYMLDKHDFQDS 772
+LQ LD +Q + R+ F +++ + + + ++ + +C + Y+ ++ +F+D
Sbjct: 545 ELQ----LDWQKQKGGVRRALFLASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRDK 600
Query: 773 ---VRITLDFNLTDPENG-------PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHV 822
+ I L+F+L DP+ P L + + + DCG C+ DL L V
Sbjct: 601 LSPIHIALNFSL-DPQAPVDSHGLRPALHYQSKSRIEDKAQILLDCGEDNICVPDLQLEV 659
Query: 823 ATTEKDLLIVRSQNDKFNVSLTVKNTKDS-AYNTRTIVHYSPNLVFSGIEA----IQKDS 877
+ + + + N++ +N + AY V P +SG+ S
Sbjct: 660 FGEQNHVYL--GDKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGLVRHPGNFSSLS 717
Query: 878 CE-----SNHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENV-TIYLSATSDSEEPPE 931
C+ + + C +G P ++ G + + +F +L + TI S+
Sbjct: 718 CDYFAVNQSRLLVCDLGNP-MKAGASLWGGL--RFTVPHLRDTKKTIQFDFQILSKNLNN 774
Query: 932 TLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVP-EVINSTEDIGNEINIFYLIR 990
+ SD VV+ + V+ + + + + ++ P + ED+G ++ Y +
Sbjct: 775 SQSD-VVSFRLSVEAQAQVTLNGVSKPEAVLFPVSDWHPRDQPQKEEDLGPAVHHVYELI 833
Query: 991 KSGSFPMPELKLSISFPNMTSNGYPVLYPT---GLSSSENANCRPHIFE-DPFSI--NSG 1044
G + + L +S P G +LY T GL+ + N P E DP +
Sbjct: 834 NQGPSSISQGVLELSCPQALE-GQQLLYVTRVTGLNCTTNHPINPKGLELDPEGSLHHQQ 892
Query: 1045 KKMTTSTDHLKRGT-ILDCNTCKFATITCNLT---SSDISQVNVSLILWKPTFIKSYFSS 1100
K+ S G IL C + + C L + + + +W TF++
Sbjct: 893 KREAPSRSSASSGPQILKCPEAECFRLRCELGPLHQQESQSLQLHFRVWAKTFLQREHQP 952
Query: 1101 LNL---TIRGELRSENASLVLSSSNQKRELAIQISKDGLPGR--VPLWVILLSAFAGLLL 1155
+L + L+ L ++R++A + G VPLW+I+L+ GLLL
Sbjct: 953 FSLQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLWIIILAILFGLLL 1012
Query: 1156 LMLLILALWKIGFFKR--PLKKKMEK 1179
L LLI L+K+GFFKR P MEK
Sbjct: 1013 LGLLIYILYKLGFFKRSLPYGTAMEK 1038
Score = 45.8 bits (107), Expect = 2e-04
Identities = 43/148 (29%), Positives = 64/148 (43%), Gaps = 18/148 (12%)
Query: 5 PRARPGVAVACCWLLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYE-NEEGKWVL 63
PR RP + LL R FN+D + SGP FG++V+ Y +G VL
Sbjct: 19 PRRRPPLLPLLLLLLPPPPRVG-GFNLDAEAPAVLSGPPGSFFGFSVEFYRPGTDGVSVL 77
Query: 64 IGSPLVGQPKN---RTGDVYKCPVGRGESLPCVKLDLP------VNTSIPN-----VTEV 109
+G+P + + G VY CP G + C ++ + +S+ + E
Sbjct: 78 VGAPKANTSQPGVLQGGAVYLCPWGASPT-QCTPIEFDSKGSRLLESSLSSSEGEEPVEY 136
Query: 110 KENMTFGSTLVTNPNGGFLACGPLYAYR 137
K FG+T V LAC PLY++R
Sbjct: 137 KSLQWFGAT-VRAHGSSILACAPLYSWR 163
>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
Length = 1012
Score = 193 bits (491), Expect = 7e-49
Identities = 211/842 (25%), Positives = 356/842 (42%), Gaps = 120/842 (14%)
Query: 422 NVESTKKNEPLA----------SYLGYTVNSATASSGDVL--YIAGQPRYNHT-GQVIIY 468
NV S K N LA SYLGY+V + +GD + +++G PR T G V IY
Sbjct: 192 NVYSIKYNNQLATRTAQAIFDDSYLGYSV-AVGDFNGDGIDDFVSGVPRAARTLGMVYIY 250
Query: 469 RMEDG-NIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGT----EKEEQ 523
DG N+ L +GEQ+ +YFG + TDI+ D D+ +GAP++M + +E
Sbjct: 251 ---DGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVF-IGAPLFMDRGSDGKLQEV 306
Query: 524 GKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNL 583
G+V V +L + ++Q TT+ ARFG+AIA + DL+
Sbjct: 307 GQVSV-SLQRASGDFQ-------------------TTKLNGFEVFARFGSAIAPLGDLDQ 346
Query: 584 DGFNDIVIGAPLE-DDHGGAVYIYHGSGKTIRKEYAQRIPSGGDGKTLK-FFGQSIHGEM 641
DGFNDI I AP +D G VYI++G + +Q + +++ FG S+ G
Sbjct: 347 DGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGAT 406
Query: 642 DLNGDGLTDVTIGGLG--GAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGK--ETVC 697
D++ +G D+ +G G A L+ +R V V + P+ +N K C + G + C
Sbjct: 407 DIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSC 466
Query: 698 INATVCFDVKLKSKEDTIYEADLQYRVTLDSLRQ---ISRSFFSGTQERKVQRNITVRKS 754
N C +K K + + Q + LD L+Q I R+ F ++ +N+T+ +
Sbjct: 467 FNVRFC--LKADGKGVLPRKLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRG 524
Query: 755 ---ECTKHSFYMLDKHDFQDSV-------RITLDFNLTDPENG--PVLDDSLPNSVHEYI 802
+C + Y+ D+ +F+D + LD+ G P+L+ P ++
Sbjct: 525 GLMQCEELIAYLRDESEFRDKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQA 584
Query: 803 PFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYS 862
DCG C L + V + +K + I ++ + + +N + AY IV
Sbjct: 585 HILLDCGEDNVCKPKLEVSVDSDQKKIYI--GDDNPLTLIVKAQNQGEGAYEAELIVSIP 642
Query: 863 PNLVFSGI----EAIQKDSC-----ESNHNITCKVGYPFLRRGEMVTFKILFQFNTSYLM 913
F G+ EA+ + SC + C +G P ++ G + + F + M
Sbjct: 643 LQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNP-MKAGTQLLAGLRFSVHQQSEM 701
Query: 914 ENVTIYLSATSDSEEPPETLSDNV---VNISIPVKYEVGLQFYSSASEYHISIAA-NETV 969
+ S D + L D V V+ + + ++ +S HI + N
Sbjct: 702 DT-----SVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEH 756
Query: 970 PEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENAN 1029
E + ED+G + Y +R +G + L + +P +N +LY N
Sbjct: 757 KENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNN-TLLYILHYDIDGPMN 815
Query: 1030 CRPHIFEDPFSINSGKKMTTST----------DHL--------KRGTI--LDCNTCKFAT 1069
C + +P I TT DHL G I L C +
Sbjct: 816 CTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGCGVAQCLK 875
Query: 1070 ITCNLTSSDISQ---VNVSLILWKPTFIKSYFSSLNLTIRG-------ELRSENASLVLS 1119
I C + D + + V +LW TF+ + + +++ E +N +
Sbjct: 876 IVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDI 935
Query: 1120 SSNQKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFK--RPLKKKM 1177
+++ + P VP+WVI+L+ AGLLLL +L+ ++++GFFK RP +++
Sbjct: 936 TNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQ 995
Query: 1178 EK 1179
E+
Sbjct: 996 ER 997
Score = 49.3 bits (116), Expect = 2e-05
Identities = 42/145 (28%), Positives = 60/145 (41%), Gaps = 14/145 (9%)
Query: 3 PRPRARPGVAVACCWLLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWV 62
PR R R G L ++L C +FN+DV + +SGP FG+ V + +
Sbjct: 5 PRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRM 64
Query: 63 LIGSPLVGQPKNRT--------GDVYKCPVGRGESLPCVKLDLPVNTSI--PNVTEVKEN 112
+ LVG PK T G V KC ++ D N + E K +
Sbjct: 65 FL---LVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSH 121
Query: 113 MTFGSTLVTNPNGGFLACGPLYAYR 137
FG++ V + LAC PLY +R
Sbjct: 122 QWFGAS-VRSKQDKILACAPLYHWR 145
>gi|49170034 integrin, alpha 8 [Homo sapiens]
Length = 1063
Score = 192 bits (489), Expect = 1e-48
Identities = 220/885 (24%), Positives = 375/885 (42%), Gaps = 136/885 (15%)
Query: 379 QTGFSAH-YSQDWVMLGAVGAYDWNGTVVMQKASQIIIP---RNTTFNVESTKKNEPLA- 433
Q GFS Y +++G G++ W G V+ + II ++ + K+ E
Sbjct: 201 QAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVADIIANYSFKDILRKLAGEKQTEVAPA 260
Query: 434 ----SYLGYTVNSA--TASSGDVLYIAGQPR-YNHTGQVIIYRMEDGNIKILQTLSGEQI 486
SYLGY+V + T S L +AG PR + G V I D + +Q +GEQ+
Sbjct: 261 SYDDSYLGYSVAAGEFTGDSQQEL-VAGIPRGAQNFGYVSIINSTD--MTFIQNFTGEQM 317
Query: 487 GSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKE----EQGKVYVYALNQTRFEYQMSL 542
SYFG + +D++ D D+L VGAP++M E E E G++Y+Y
Sbjct: 318 ASYFGYTVVVSDVNSDGLDDVL-VGAPLFMEREFESNPREVGQIYLYLQ----------- 365
Query: 543 EPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLED-DHGG 601
SS E G RFG+A+A + DLN DG+NDI IG P D G
Sbjct: 366 -------VSSLLFRDPQILTGTETFG-RFGSAMAHLGDLNQDGYNDIAIGVPFAGKDQRG 417
Query: 602 AVYIYHGSGKTIRKEYAQ---------RIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVT 652
V IY+G+ + + +Q +PSG FG ++ G+ D++ + D+
Sbjct: 418 KVLIYNGNKDGLNTKPSQVLQGVWASHAVPSG--------FGFTLRGDSDIDKNDYPDLI 469
Query: 653 IG--GLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKET--VCINATVCFDVKL 708
+G G G A++ +R V V + P +N++ K C + T C + VC V
Sbjct: 470 VGAFGTGKVAVYRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTG 529
Query: 709 KSKEDTIYEADLQYRVTLDSLRQ---ISRSFFSGTQERKVQRNITVRKS---ECTKHSFY 762
+S +TI L V LDSL+Q I R+ F + + +++ +C Y
Sbjct: 530 QSIANTIV---LMAEVQLDSLKQKGAIKRTLFLDNHQAHRVFPLVIKRQKSHQCQDFIVY 586
Query: 763 MLDKHDFQDS---VRITLDFNLTDP------ENGPVLDDSLPNSVHEYIPFAKDCGNKEK 813
+ D+ +F+D + I+L+++L + E P+L+ N V E DCG
Sbjct: 587 LRDETEFRDKLSPINISLNYSLDESTFKEGLEVKPILNYYRENIVSEQAHILVDCGEDNL 646
Query: 814 CISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAI 873
C+ DL L A +K +I+ +N + + +N + AY V + GIE
Sbjct: 647 CVPDLKLS-ARPDKHQVIIGDENHLMLI-INARNEGEGAYEAELFVMIPEEADYVGIERN 704
Query: 874 QKD----SCESN-HNIT----CKVGYPFLRRGEMVTFKILFQFNTSYLME---NVTIYLS 921
K SCE N+T C +G P + + + +F L + ++ L
Sbjct: 705 NKGFRPLSCEYKMENVTRMVVCDLGNPMVSG---TNYSLGLRFAVPRLEKTNMSINFDLQ 761
Query: 922 ATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVPEVI-NSTEDIG 980
S +++ P++ N V++ I + ++ + I + + PE + E++G
Sbjct: 762 IRSSNKDNPDS---NFVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVG 818
Query: 981 NEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFS 1040
+ Y + G + + L + +P + + +LY + + C+P+ +P
Sbjct: 819 PLVEHIYELHNIGPSTISDTILEVGWPFSARDEF-LLYIFHIQTLGPLQCQPNPNINPQD 877
Query: 1041 IN-----------SGKKMTTSTDHLKR--------------GTILDCNTCKFATITC--- 1072
I S ++ HL R IL+C + I+C
Sbjct: 878 IKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSPAKILNCTNIECLQISCAVG 937
Query: 1073 NLTSSDISQVNVSLILWKPTFIK------SYFSSLNLTIRGELRSENASLVLSSSNQKRE 1126
L + + + V LW TF++ + S ++ ++ ++ + + S +
Sbjct: 938 RLEGGESAVLKVRSRLWAHTFLQRKNDPYALASLVSFEVKKMPYTDQPAKLPEGSIAIKT 997
Query: 1127 LAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIGFFKR 1171
I + + + +PLWVI+L+ GLL+L +L LALWK GFF R
Sbjct: 998 SVIWATPN-VSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDR 1041
Score = 56.2 bits (134), Expect = 2e-07
Identities = 48/154 (31%), Positives = 63/154 (40%), Gaps = 24/154 (15%)
Query: 3 PRPRARPGVAVACCWLLTVVLR----CCVSFNVDVKNSMTFSGPVEDMFGYTVQQYENEE 58
PR P +A CC + + C +FN+DV+ +SGP FGY V + +
Sbjct: 9 PRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVDFHIPD- 67
Query: 59 GKWVLIGSPLVGQPKNRT--------GDVYKCPVGRGESLPC--VKLDLPVNTSI----- 103
S LVG PK T G VY CP S C + D N I
Sbjct: 68 ---ARTASVLVGAPKANTSQPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRVNGT 124
Query: 104 PNVTEVKENMTFGSTLVTNPNGGFLACGPLYAYR 137
E K N FG+T+ + G +AC PLY +R
Sbjct: 125 KEPIEFKSNQWFGATVKAH-KGKVVACAPLYHWR 157
>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
Length = 1039
Score = 187 bits (476), Expect = 4e-47
Identities = 210/880 (23%), Positives = 362/880 (41%), Gaps = 106/880 (12%)
Query: 372 SFEMEMSQTGFSAHYSQDW-VMLGAVGAYDWNGTVVMQKASQIII---PRNTTFNVES-- 425
S++ + GFS+ +Q ++LGA G Y + G + + I P ++V S
Sbjct: 192 SWDKRYCEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVADIFSSYRPGILLWHVSSQS 251
Query: 426 ----TKKNEPLASYLGYTVNSATASSGDVL---YIAGQPRYNHT-GQVIIYRMEDGNIKI 477
+ E Y GY+V + GD+ Y+ G P ++ T G V I D +
Sbjct: 252 LSFDSSNPEYFDGYWGYSV-AVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL---DSYYQR 307
Query: 478 LQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKE----EQGKVYVYALNQ 533
L L GEQ+ SYFG + TD++ D D LLVGAP+YM + + E G+VY++ Q
Sbjct: 308 LHRLRGEQMASYFGHSVAVTDVNGDGRHD-LLVGAPLYMESRADRKLAEVGRVYLFL--Q 364
Query: 534 TRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGA 593
R + + + T RFG+AIA + DL+ DG+NDI + A
Sbjct: 365 PRGPHALGAPSLLLT---------------GTQLYGRFGSAIAPLGDLDRDGYNDIAVAA 409
Query: 594 PLEDDHG-GAVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVT 652
P G G V ++ G + +R +Q + S T FG S+ G +D++ +G D+
Sbjct: 410 PYGGPSGRGQVLVFLGQSEGLRSRPSQVLDS--PFPTGSAFGFSLRGAVDIDDNGYPDLI 467
Query: 653 IGGLGGAALFWSRDVAVVKVTMNF-EPNKVNIQKKNCHMEGKETV--CINATVCFDVKLK 709
+G G + R VVK ++ + +N K+C + +T C N +C
Sbjct: 468 VGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGA--- 524
Query: 710 SKEDTIYEADLQYRVTLDSL--RQISRSFFSGTQERKVQRNITVRKSE---CTKHSFYML 764
+ + + L + LD RQ R G+Q+ N+ + C ++
Sbjct: 525 TGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLR 584
Query: 765 DKHDFQDSVR---ITLDFNLTDPENGPVLDDSLPNSVH--EYIPFAKDCGNKEKCISDLS 819
D+ DF+D + ++L+ +L E G L H E DCG + C+ L
Sbjct: 585 DEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQEQTRIVLDCGEDDVCVPQLQ 644
Query: 820 LHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVF----SGIEAIQK 875
L + T LL+ ++ + + N + AY VH + S +E ++
Sbjct: 645 LTASVTGSPLLV--GADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNVEGFER 702
Query: 876 DSCESNHN-----ITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPP 930
C + C++G P + ++ ++ N E+V+ L S + + P
Sbjct: 703 LICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNP 762
Query: 931 ETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIR 990
+ +V + +PV+ E ++ ++ + +AA E E NS + G ++ Y +
Sbjct: 763 NS---KIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGEREQ-NSLDSWGPKVEHTYELH 818
Query: 991 KSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTS 1050
+G + L LSI P S +LY + C P +P ++ G + +
Sbjct: 819 NNGPGTVNGLHLSIHLPGQ-SQPSDLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSP 877
Query: 1051 TD----HLKRG------------------TILDCNTCKFATITCNLTSSDISQ---VNVS 1085
+ H KR ++ C++ + C+L Q V V
Sbjct: 878 SPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTVL 937
Query: 1086 LILWKPTFIKSYFSSLNLTIRGELRSENASLV---LSSSNQKRELAIQISKDGLPGRVPL 1142
LW P+ + L + LS + ++ Q+ + +P+
Sbjct: 938 AFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAIPI 997
Query: 1143 WVILLSAFAGLLLLMLLILALWKIGFFKR---PLKKKMEK 1179
W +L+ GLLLL +L+LA+WK+GFFKR PL++ E+
Sbjct: 998 WWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDEE 1037
Score = 36.2 bits (82), Expect = 0.19
Identities = 24/96 (25%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 17 WLLTVVLRCCV----SFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGK-WVLIGSP-LVG 70
W+L ++ C + N+D ++GP FG+++ +++ G+ +++G+P +G
Sbjct: 16 WVLLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRTLG 75
Query: 71 QPKNRTGDVYKCPVGRGESLPCVKLDLPVNTSIPNV 106
+ TG V+ CP R E C L + NV
Sbjct: 76 PSQEETGGVFLCP-WRAEGGQCPSLLFDLRDETRNV 110
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor
[Homo sapiens]
Length = 3063
Score = 110 bits (276), Expect = 6e-24
Identities = 71/192 (36%), Positives = 108/192 (56%), Gaps = 17/192 (8%)
Query: 164 VQECSTQL--DIVIVLDGSNSI--YPWDSVTAFLNDLLERMDIGPKQTQVGIVQYGENVT 219
+Q+CS D+V ++DGS S+ + + F+ L+ DIG ++T+VG+VQY +
Sbjct: 130 IQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTR 189
Query: 220 HEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGARRGVKKVMVIV 279
EFNLN+Y +E+L A KKI +GG TMT ID K FTE+ GAR G KV +I+
Sbjct: 190 TEFNLNQYYQRDELLAAIKKIPYKGG-NTMTGDAIDYLVKNTFTESAGARVGFPKVAIII 248
Query: 280 TDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHF 339
TDG+S D + ++ + ++ FS+ I + +E+K IAS P+ H
Sbjct: 249 TDGKSQDEVEIP--ARELRNVGVEVFSLGIKAA----------DAKELKQIASTPSLNHV 296
Query: 340 FNVSDELALVTI 351
FNV++ A+V I
Sbjct: 297 FNVANFDAIVDI 308
Score = 94.0 bits (232), Expect = 8e-19
Identities = 74/255 (29%), Positives = 127/255 (49%), Gaps = 30/255 (11%)
Query: 107 TEVKENMTFGSTLVTNPNGGFLA--CGPLYAYRCGHLHYTTGICSDVSPTFQVVNSIAPV 164
T V E + G+T N G F PL L TT V+ ++
Sbjct: 1141 TVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT-----------VMPILSSG 1189
Query: 165 QECST--QLDIVIVLDGSNSI--YPWDSVTAFLNDLLERMDIGPKQTQVGIVQYGENVTH 220
EC T + DIV+++DGS SI + +V +F++ ++E DIGPK+ Q+ + QY +
Sbjct: 1190 MECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRT 1249
Query: 221 EFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGARRGVKKVMVIVT 280
E+ LN + + +L A + +GG T+T + ++ R++ F G R +K+ V++T
Sbjct: 1250 EWQLNAHRDKKSLLQAVANLPYKGG-NTLTGMALNFIRQQNFRTQAGMRPRARKIGVLIT 1308
Query: 281 DGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFF 340
DG+S D+ ++ + +DE ++ F+I I + E+K IA++P + H +
Sbjct: 1309 DGKSQDD--VEAPSKKLKDEGVELFAIGIKNADE----------VELKMIATDPDDTHAY 1356
Query: 341 NVSDELALVTIVKTL 355
NV+D +L IV L
Sbjct: 1357 NVADFESLSRIVDDL 1371
Score = 91.3 bits (225), Expect = 5e-18
Identities = 58/185 (31%), Positives = 96/185 (51%), Gaps = 19/185 (10%)
Query: 166 ECST----QLDIVIVLDGSNSI--YPWDSVTAFLNDLLERMDIGPKQTQVGIVQYGENVT 219
ECS + DIV ++DGS SI + V AFL L++ +I P + Q+ +VQY +
Sbjct: 430 ECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPH 489
Query: 220 HEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGARRGVKKVMVIV 279
EF L K++ E+++ A RGG T T + R++ F ++G+R V KVM+++
Sbjct: 490 TEFTLKKFTKVEDIIEAINTFPYRGG-STNTGKAMTYVREKIFVPSKGSRSNVPKVMILI 548
Query: 280 TDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHF 339
TDG+S D R + + +++ F++ + + E+++IAS P E H
Sbjct: 549 TDGKSSDAFRDPAI--KLRNSDVEIFAVGVKDAVR----------SELEAIASPPAETHV 596
Query: 340 FNVSD 344
F V D
Sbjct: 597 FTVED 601
Score = 76.6 bits (187), Expect = 1e-13
Identities = 63/198 (31%), Positives = 92/198 (46%), Gaps = 20/198 (10%)
Query: 153 PTFQVVNSIAPVQEC--STQLDIVIVLDGSNSIYP--WDSVTAFLNDLLERMD-IGPKQT 207
PT +I P ++ + DIV + D S SI ++ V F+ + + D I P
Sbjct: 2302 PTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGI 2361
Query: 208 QVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARG 267
QV VQY + V EF LN Y+ L A + I RGG T T + +++ T G
Sbjct: 2362 QVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGG-NTRTGKALTFIKEKVLTWESG 2420
Query: 268 ARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILG-SYNRGNLSTEKFVEE 326
R+ V KV+V+VTDG S D +KK + F + + YN E
Sbjct: 2421 MRKNVPKVLVVVTDGRSQD--EVKKAALVIQQSGFSVFVVGVADVDYN-----------E 2467
Query: 327 IKSIASEPTEKHFFNVSD 344
+ +IAS+P+E+H F V D
Sbjct: 2468 LANIASKPSERHVFIVDD 2485
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 97.4 bits (241), Expect = 7e-20
Identities = 57/186 (30%), Positives = 109/186 (58%), Gaps = 15/186 (8%)
Query: 172 DIVIVLDGSNSI--YPWDSVTAFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSS 229
DIVI++DGS SI + + V FL +L+ D+G ++T++G+ QY + E++LN +S+
Sbjct: 158 DIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLAQYSGDPRIEWHLNAFST 217
Query: 230 TEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGESHDNHR 289
+EV+ A + + +GG T+T L ++ + +F G+R GV K+ +++TDG+S D+
Sbjct: 218 KDEVIEAVRNLPYKGG-NTLTGLALNYIFENSFKPEAGSRTGVSKIGILITDGKSQDD-- 274
Query: 290 LKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALV 349
+ ++ + ++ F+I + + V E++ IASEP H +NV++ +
Sbjct: 275 IIPPSRNLRESGVELFAIGVKNA----------DVNELQEIASEPDSTHVYNVAEFDLMH 324
Query: 350 TIVKTL 355
T+V++L
Sbjct: 325 TVVESL 330
Score = 87.4 bits (215), Expect = 7e-17
Identities = 64/197 (32%), Positives = 103/197 (52%), Gaps = 20/197 (10%)
Query: 153 PTFQVVNSIAPVQEC--STQLDIVIVLDGSNSIYP--WDSVTAFLNDLLERMD-IGPKQT 207
PTF +I P +E + + D+V ++DGS SI ++ + +FL + ++ IG T
Sbjct: 1013 PTFPP--TIPPAKEVCKAAKADLVFMVDGSWSIGDENFNKIISFLYSTVGALNKIGTDGT 1070
Query: 208 QVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARG 267
QV +VQ+ ++ EF LN Y + E +L A K I +GG T T I R FT G
Sbjct: 1071 QVAMVQFTDDPRTEFKLNAYKTKETLLDAIKHISYKGGN-TKTGKAIKYVRDTLFTAESG 1129
Query: 268 ARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEI 327
RRG+ KV+V++TDG S D+ + K+ ++ + + F+I + + E+
Sbjct: 1130 TRRGIPKVIVVITDGRSQDD--VNKISREMQLDGYSIFAIGV----------ADADYSEL 1177
Query: 328 KSIASEPTEKHFFNVSD 344
SI S+P+ +H F V D
Sbjct: 1178 VSIGSKPSARHVFFVDD 1194
>gi|62548862 matrilin 2 isoform b precursor [Homo sapiens]
Length = 937
Score = 94.4 bits (233), Expect = 6e-19
Identities = 69/209 (33%), Positives = 107/209 (51%), Gaps = 20/209 (9%)
Query: 172 DIVIVLDGSNSIYPWD--SVTAFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSS 229
D+V ++D S S+ D V F+ D+L+ +DIGP T+VG++QYG V +EF+L +
Sbjct: 57 DLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTFKR 116
Query: 230 TEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGA---RRGVKKVMVIVTDGESHD 286
EV A K+ ++ TMT L I A AF+EA GA R V +V++IVTDG D
Sbjct: 117 KSEVERAVKR-MRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTDGRPQD 175
Query: 287 NHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDEL 346
+ + +V D I F+I + G + +KSI SEP E H F V++
Sbjct: 176 S--VAEVAAKARDTGILIFAIGV------GQVD----FNTLKSIGSEPHEDHVFLVANFS 223
Query: 347 ALVTIVKTLGERIFALE--ATADQSAASF 373
+ T+ +++ +T + + A F
Sbjct: 224 QIETLTSVFQKKLCTAHMCSTLEHNCAHF 252
Score = 77.4 bits (189), Expect = 7e-14
Identities = 57/216 (26%), Positives = 104/216 (48%), Gaps = 23/216 (10%)
Query: 138 CGHLHYTTG---ICSDVSPTFQVVNSIAPVQECST-QLDIVIVLDGSNSIYP--WDSVTA 191
C H+ G IC S F + ++C+ +D+V V+DGS S+ ++ V
Sbjct: 618 CEHICVNNGNSYICK-CSEGFVLAEDGRRCKKCTEGPIDLVFVIDGSKSLGEENFEVVKQ 676
Query: 192 FLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTA 251
F+ +++ + I PK +VG++QY V EF L ++S +++ A ++ G+ +MT
Sbjct: 677 FVTGIIDSLTISPKAARVGLLQYSTQVHTEFTLRNFNSAKDMKKAVAH-MKYMGKGSMTG 735
Query: 252 LGIDTARKEAFTEARGAR---RGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIA 308
L + + +FT+ GAR V + ++ TDG + D+ + + + I +++
Sbjct: 736 LALKHMFERSFTQGEGARPLSTRVPRAAIVFTDGRAQDD--VSEWASKAKANGITMYAVG 793
Query: 309 ILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSD 344
+ + EE++ IASEPT KH F D
Sbjct: 794 V----------GKAIEEELQEIASEPTNKHLFYAED 819
>gi|62548860 matrilin 2 isoform a precursor [Homo sapiens]
Length = 956
Score = 94.4 bits (233), Expect = 6e-19
Identities = 69/209 (33%), Positives = 107/209 (51%), Gaps = 20/209 (9%)
Query: 172 DIVIVLDGSNSIYPWD--SVTAFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSS 229
D+V ++D S S+ D V F+ D+L+ +DIGP T+VG++QYG V +EF+L +
Sbjct: 57 DLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTFKR 116
Query: 230 TEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGA---RRGVKKVMVIVTDGESHD 286
EV A K+ ++ TMT L I A AF+EA GA R V +V++IVTDG D
Sbjct: 117 KSEVERAVKR-MRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTDGRPQD 175
Query: 287 NHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDEL 346
+ + +V D I F+I + G + +KSI SEP E H F V++
Sbjct: 176 S--VAEVAAKARDTGILIFAIGV------GQVD----FNTLKSIGSEPHEDHVFLVANFS 223
Query: 347 ALVTIVKTLGERIFALE--ATADQSAASF 373
+ T+ +++ +T + + A F
Sbjct: 224 QIETLTSVFQKKLCTAHMCSTLEHNCAHF 252
Score = 77.4 bits (189), Expect = 7e-14
Identities = 57/216 (26%), Positives = 104/216 (48%), Gaps = 23/216 (10%)
Query: 138 CGHLHYTTG---ICSDVSPTFQVVNSIAPVQECST-QLDIVIVLDGSNSIYP--WDSVTA 191
C H+ G IC S F + ++C+ +D+V V+DGS S+ ++ V
Sbjct: 618 CEHICVNNGNSYICK-CSEGFVLAEDGRRCKKCTEGPIDLVFVIDGSKSLGEENFEVVKQ 676
Query: 192 FLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTA 251
F+ +++ + I PK +VG++QY V EF L ++S +++ A ++ G+ +MT
Sbjct: 677 FVTGIIDSLTISPKAARVGLLQYSTQVHTEFTLRNFNSAKDMKKAVAH-MKYMGKGSMTG 735
Query: 252 LGIDTARKEAFTEARGAR---RGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIA 308
L + + +FT+ GAR V + ++ TDG + D+ + + + I +++
Sbjct: 736 LALKHMFERSFTQGEGARPLSTRVPRAAIVFTDGRAQDD--VSEWASKAKANGITMYAVG 793
Query: 309 ILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSD 344
+ + EE++ IASEPT KH F D
Sbjct: 794 V----------GKAIEEELQEIASEPTNKHLFYAED 819
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,686,177
Number of Sequences: 37866
Number of extensions: 1901568
Number of successful extensions: 4869
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 4328
Number of HSP's gapped (non-prelim): 163
length of query: 1179
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1066
effective length of database: 13,968,660
effective search space: 14890591560
effective search space used: 14890591560
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.