Search of human proteins with 31317241

Search of human proteins with 31317241

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31317241 interleukin 22-binding protein isoform 2 [Homo
sapiens]
         (231 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31317241 interleukin 22-binding protein isoform 2 [Homo sapiens]   483   e-137
gi|16418459 interleukin 22-binding protein isoform 1 [Homo sapiens]   467   e-132
gi|31317243 interleukin 22-binding protein isoform 3 [Homo sapiens]   272   2e-73
gi|31083156 interleukin 20 receptor, alpha [Homo sapiens]             132   2e-31
gi|31317239 interleukin 22 receptor, alpha 1 [Homo sapiens]           103   2e-22
gi|25014103 interleukin 28 receptor, alpha isoform 1 [Homo sapiens]    63   2e-10
gi|28416911 interleukin 28 receptor, alpha isoform 3 [Homo sapiens]    63   2e-10
gi|28416909 interleukin 28 receptor, alpha isoform 2 [Homo sapiens]    63   2e-10
gi|4503641 coagulation factor III precursor [Homo sapiens]             61   7e-10
gi|24430215 interleukin 10 receptor, beta precursor [Homo sapiens]     61   7e-10
gi|40255073 interleukin 20 receptor beta precursor [Homo sapiens]      61   9e-10
gi|222136575 interleukin 10 receptor, alpha precursor [Homo sapi...    57   2e-08
gi|46488932 interferon-alpha receptor 1 precursor [Homo sapiens]       54   1e-07
gi|4557880 interferon gamma receptor 1 precursor [Homo sapiens]        51   1e-06
gi|46488937 interferon alpha/beta receptor 2 isoform a precursor...    40   0.002
gi|46488935 interferon alpha/beta receptor 2 isoform b precursor...    40   0.002
gi|19923129 interferon alpha/beta receptor 2 isoform b precursor...    40   0.002
gi|47419934 interferon gamma receptor 2 precursor [Homo sapiens]       39   0.004
gi|62632748 killer-cell Ig-like receptor [Homo sapiens]                33   0.27 
gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo sapi...    30   1.7  
gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo sap...    30   1.7  
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         29   3.9  
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         29   3.9  
gi|4503993 growth hormone receptor precursor [Homo sapiens]            28   6.6  
gi|22212918 ciliary neurotrophic factor receptor preproprotein [...    28   6.6  
gi|4502931 ciliary neurotrophic factor receptor preproprotein [H...    28   6.6  

>gi|31317241 interleukin 22-binding protein isoform 2 [Homo sapiens]
          Length = 231

 Score =  483 bits (1244), Expect = e-137
 Identities = 231/231 (100%), Positives = 231/231 (100%)

Query: 1   MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPGRALTGNSSVY 60
           MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPGRALTGNSSVY
Sbjct: 1   MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPGRALTGNSSVY 60

Query: 61  FVQYKIYGQRQWKNKEDCWGTQELSCDLTSETSDIQEPYYGRVRAASAGSYSEWSMTPRF 120
           FVQYKIYGQRQWKNKEDCWGTQELSCDLTSETSDIQEPYYGRVRAASAGSYSEWSMTPRF
Sbjct: 61  FVQYKIYGQRQWKNKEDCWGTQELSCDLTSETSDIQEPYYGRVRAASAGSYSEWSMTPRF 120

Query: 121 TPWWETKIDPPVMNITQVNGSLLVILHAPNLPYRYQKEKNVSIEDYYELLYRVFIINNSL 180
           TPWWETKIDPPVMNITQVNGSLLVILHAPNLPYRYQKEKNVSIEDYYELLYRVFIINNSL
Sbjct: 121 TPWWETKIDPPVMNITQVNGSLLVILHAPNLPYRYQKEKNVSIEDYYELLYRVFIINNSL 180

Query: 181 EKEQKVYEGAHRAVEIEALTPHSSYCVVAEIYQPMLDRRSQRSEERCVEIP 231
           EKEQKVYEGAHRAVEIEALTPHSSYCVVAEIYQPMLDRRSQRSEERCVEIP
Sbjct: 181 EKEQKVYEGAHRAVEIEALTPHSSYCVVAEIYQPMLDRRSQRSEERCVEIP 231


>gi|16418459 interleukin 22-binding protein isoform 1 [Homo sapiens]
          Length = 263

 Score =  467 bits (1201), Expect = e-132
 Identities = 231/263 (87%), Positives = 231/263 (87%), Gaps = 32/263 (12%)

Query: 1   MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPGRALTGNSSVY 60
           MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPGRALTGNSSVY
Sbjct: 1   MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPGRALTGNSSVY 60

Query: 61  FVQYKI--------------------------------YGQRQWKNKEDCWGTQELSCDL 88
           FVQYKI                                YGQRQWKNKEDCWGTQELSCDL
Sbjct: 61  FVQYKIMFSCSMKSSHQKPSGCWQHISCNFPGCRTLAKYGQRQWKNKEDCWGTQELSCDL 120

Query: 89  TSETSDIQEPYYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQVNGSLLVILHA 148
           TSETSDIQEPYYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQVNGSLLVILHA
Sbjct: 121 TSETSDIQEPYYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQVNGSLLVILHA 180

Query: 149 PNLPYRYQKEKNVSIEDYYELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPHSSYCVV 208
           PNLPYRYQKEKNVSIEDYYELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPHSSYCVV
Sbjct: 181 PNLPYRYQKEKNVSIEDYYELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPHSSYCVV 240

Query: 209 AEIYQPMLDRRSQRSEERCVEIP 231
           AEIYQPMLDRRSQRSEERCVEIP
Sbjct: 241 AEIYQPMLDRRSQRSEERCVEIP 263


>gi|31317243 interleukin 22-binding protein isoform 3 [Homo sapiens]
          Length = 130

 Score =  272 bits (695), Expect = 2e-73
 Identities = 125/125 (100%), Positives = 125/125 (100%)

Query: 1   MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPGRALTGNSSVY 60
           MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPGRALTGNSSVY
Sbjct: 1   MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPGRALTGNSSVY 60

Query: 61  FVQYKIYGQRQWKNKEDCWGTQELSCDLTSETSDIQEPYYGRVRAASAGSYSEWSMTPRF 120
           FVQYKIYGQRQWKNKEDCWGTQELSCDLTSETSDIQEPYYGRVRAASAGSYSEWSMTPRF
Sbjct: 61  FVQYKIYGQRQWKNKEDCWGTQELSCDLTSETSDIQEPYYGRVRAASAGSYSEWSMTPRF 120

Query: 121 TPWWE 125
           TPWWE
Sbjct: 121 TPWWE 125


>gi|31083156 interleukin 20 receptor, alpha [Homo sapiens]
          Length = 553

 Score =  132 bits (333), Expect = 2e-31
 Identities = 74/199 (37%), Positives = 107/199 (53%), Gaps = 2/199 (1%)

Query: 30  KPQRVQFQSRNFHNILQWQPGRALTGNSSVYFVQYKIYGQRQWKNKEDCWGTQELSCDLT 89
           KP  + F S N  N+LQW P   L G    Y VQY IYGQ++W NK +C       CDL+
Sbjct: 39  KPANITFLSINMKNVLQWTPPEGLQGVKVTYTVQYFIYGQKKWLNKSECRNINRTYCDLS 98

Query: 90  SETSDIQEPYYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQVNGSLLVILHAP 149
           +ETSD +  YY +V+A      S+W+ + RF P+ ET+I PP + +T    S+ V+L AP
Sbjct: 99  AETSDYEHQYYAKVKAIWGTKCSKWAESGRFYPFLETQIGPPEVALTTDEKSISVVLTAP 158

Query: 150 NLPYRYQKEKNVSIEDYY-ELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPHSSYCVV 208
               R  ++  VS++  Y  L Y V ++N    +        H  V +  L P++ YCV 
Sbjct: 159 EKWKRNPEDLPVSMQQIYSNLKYNVSVLNTKSNRTWSQCVTNHTLV-LTWLEPNTLYCVH 217

Query: 209 AEIYQPMLDRRSQRSEERC 227
            E + P   RR+Q SE++C
Sbjct: 218 VESFVPGPPRRAQPSEKQC 236


>gi|31317239 interleukin 22 receptor, alpha 1 [Homo sapiens]
          Length = 574

 Score =  103 bits (256), Expect = 2e-22
 Identities = 66/190 (34%), Positives = 93/190 (48%), Gaps = 4/190 (2%)

Query: 32  QRVQFQSRNFHNILQWQPGRALTGNSSVYFVQYKIYGQRQWKNKEDCWGTQELSCDLTSE 91
           Q V+FQS NF NIL W  G   T ++ VY ++YK YG+R W  K+ C      SC+LT E
Sbjct: 26  QHVKFQSSNFENILTWDSGPEGTPDT-VYSIEYKTYGERDWVAKKGCQRITRKSCNLTVE 84

Query: 92  TSDIQEPYYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQVNGSLLVILHAPNL 151
           T ++ E YY RV A SAG  S   MT RF+    T + PP +       S+ +I+H    
Sbjct: 85  TGNLTELYYARVTAVSAGGRSATKMTDRFSSLQHTTLKPPDVTCISKVRSIQMIVHPTPT 144

Query: 152 PYRYQKEKNVSIED-YYELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPHSSYCVVAE 210
           P R      +++ED +++L Y + +  N     Q    G  R  E   LTP + +     
Sbjct: 145 PIRAGDGHRLTLEDIFHDLFYHLELQVN--RTYQMHLGGKQREYEFFGLTPDTEFLGTIM 202

Query: 211 IYQPMLDRRS 220
           I  P   + S
Sbjct: 203 ICVPTWAKES 212


>gi|25014103 interleukin 28 receptor, alpha isoform 1 [Homo sapiens]
          Length = 520

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 40/111 (36%), Positives = 56/111 (50%), Gaps = 7/111 (6%)

Query: 31  PQRVQFQSRNFHNILQWQPGRALTGNSS--VYFVQYKIYG-QRQWKNKEDCWGTQELSCD 87
           PQ V   S+NF   L W PG    GN     YFV Y+    +R+W+  E+C GT+EL C 
Sbjct: 27  PQNVTLLSQNFSVYLTWLPG---LGNPQDVTYFVAYQSSPTRRRWREVEECAGTKELLCS 83

Query: 88  LTS-ETSDIQEPYYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQ 137
           +   +  D+   + GRVR  S  S S W  +      +E +  PPV+ +TQ
Sbjct: 84  MMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEYLDYLFEVEPAPPVLVLTQ 134


>gi|28416911 interleukin 28 receptor, alpha isoform 3 [Homo sapiens]
          Length = 244

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 40/111 (36%), Positives = 56/111 (50%), Gaps = 7/111 (6%)

Query: 31  PQRVQFQSRNFHNILQWQPGRALTGNSS--VYFVQYKIYG-QRQWKNKEDCWGTQELSCD 87
           PQ V   S+NF   L W PG    GN     YFV Y+    +R+W+  E+C GT+EL C 
Sbjct: 27  PQNVTLLSQNFSVYLTWLPG---LGNPQDVTYFVAYQSSPTRRRWREVEECAGTKELLCS 83

Query: 88  LTS-ETSDIQEPYYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQ 137
           +   +  D+   + GRVR  S  S S W  +      +E +  PPV+ +TQ
Sbjct: 84  MMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEYLDYLFEVEPAPPVLVLTQ 134


>gi|28416909 interleukin 28 receptor, alpha isoform 2 [Homo sapiens]
          Length = 491

 Score = 62.8 bits (151), Expect = 2e-10
 Identities = 40/111 (36%), Positives = 56/111 (50%), Gaps = 7/111 (6%)

Query: 31  PQRVQFQSRNFHNILQWQPGRALTGNSS--VYFVQYKIYG-QRQWKNKEDCWGTQELSCD 87
           PQ V   S+NF   L W PG    GN     YFV Y+    +R+W+  E+C GT+EL C 
Sbjct: 27  PQNVTLLSQNFSVYLTWLPG---LGNPQDVTYFVAYQSSPTRRRWREVEECAGTKELLCS 83

Query: 88  LTS-ETSDIQEPYYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQ 137
           +   +  D+   + GRVR  S  S S W  +      +E +  PPV+ +TQ
Sbjct: 84  MMCLKKQDLYNKFKGRVRTVSPSSKSPWVESEYLDYLFEVEPAPPVLVLTQ 134


>gi|4503641 coagulation factor III precursor [Homo sapiens]
          Length = 295

 Score = 61.2 bits (147), Expect = 7e-10
 Identities = 55/230 (23%), Positives = 100/230 (43%), Gaps = 20/230 (8%)

Query: 11  LISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPGRALTGNSSVYFVQYKIYGQR 70
           L+ +    VAG   T  ++    + ++S NF  IL+W+P       + VY VQ       
Sbjct: 21  LLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPKPV----NQVYTVQIST-KSG 75

Query: 71  QWKNKEDCWGTQELSCDLTSE-TSDIQEPYYGRVRAASAGSYSE--------WSMTPRFT 121
            WK+K  C+ T +  CDLT E   D+++ Y  RV +  AG+           +  +P FT
Sbjct: 76  DWKSK--CFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGSAGEPLYENSPEFT 133

Query: 122 PWWETKI-DPPVMNITQVNGSLLVILHAPNLPYRYQKEKNVSIEDYY--ELLYRVFIINN 178
           P+ ET +  P + +  QV   + V +       R +    +S+ D +  +L+Y ++   +
Sbjct: 134 PYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVR-RNNTFLSLRDVFGKDLIYTLYYWKS 192

Query: 179 SLEKEQKVYEGAHRAVEIEALTPHSSYCVVAEIYQPMLDRRSQRSEERCV 228
           S   ++      +  +       +  + V A I    ++R+S  S   C+
Sbjct: 193 SSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVECM 242


>gi|24430215 interleukin 10 receptor, beta precursor [Homo sapiens]
          Length = 325

 Score = 61.2 bits (147), Expect = 7e-10
 Identities = 57/205 (27%), Positives = 90/205 (43%), Gaps = 27/205 (13%)

Query: 31  PQRVQFQSRNFHNILQWQPGRALTGN--SSVYFVQYKIYGQRQWKNKEDCWGTQELSCDL 88
           P+ V+  S NF NILQW+      GN   +  ++ Y+I+       ++ C  T    CD 
Sbjct: 24  PENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYRIF-------QDKCMNTTLTECDF 76

Query: 89  TSETSDIQEPYYG----RVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQVNGSLLV 144
           +S +       YG    RVRA  A  +S+W +   F P  +T I PP M +  +  SL +
Sbjct: 77  SSLSK------YGDHTLRVRAEFADEHSDW-VNITFCPVDDTIIGPPGMQVEVLADSLHM 129

Query: 145 ILHAPNLPYRYQ--KEKNVSIEDYYELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPH 202
              AP +   Y+    KNV    Y    Y V    N  +++ ++       V +  L P 
Sbjct: 130 RFLAPKIENEYETWTMKNV----YNSWTYNVQYWKNGTDEKFQITPQYDFEV-LRNLEPW 184

Query: 203 SSYCVVAEIYQPMLDRRSQRSEERC 227
           ++YCV    + P  ++  + SE  C
Sbjct: 185 TTYCVQVRGFLPDRNKAGEWSEPVC 209


>gi|40255073 interleukin 20 receptor beta precursor [Homo sapiens]
          Length = 311

 Score = 60.8 bits (146), Expect = 9e-10
 Identities = 52/205 (25%), Positives = 82/205 (40%), Gaps = 21/205 (10%)

Query: 31  PQRVQFQSRNFHNILQWQPGRALTGNSSVYFVQYK-----IYGQRQWKNKEDCWGTQELS 85
           PQ +   S N  ++L W P  A  G +  Y V+Y+     +Y    W     C  T+   
Sbjct: 38  PQNLSVLSTNMKHLLMWSPVIA-PGETVYYSVEYQGEYESLYTSHIWIPSSWCSLTEGPE 96

Query: 86  CDLTSETSDIQEPYYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQVNGSLLVI 145
           CD+T + +    PY  RVRA      S WS+         T +  P M IT+    L++ 
Sbjct: 97  CDVTDDIT-ATVPYNLRVRATLGSQTSAWSILKHPFNRNSTILTRPGMEITKDGFHLVIE 155

Query: 146 LHAPNLPYRYQKEKNVSIEDYYELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPHSSY 205
           L                +   +E L   +      E+  K+       V +E + P ++Y
Sbjct: 156 LE--------------DLGPQFEFLVAYWRREPGAEEHVKMVRSGGIPVHLETMEPGAAY 201

Query: 206 CVVAEIYQPMLDRRSQRSEERCVEI 230
           CV A+ +   + R S  S+  CVE+
Sbjct: 202 CVKAQTFVKAIGRYSAFSQTECVEV 226


>gi|222136575 interleukin 10 receptor, alpha precursor [Homo
           sapiens]
          Length = 578

 Score = 56.6 bits (135), Expect = 2e-08
 Identities = 58/238 (24%), Positives = 95/238 (39%), Gaps = 20/238 (8%)

Query: 1   MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQRVQFQSRNFHNILQWQPGRALTGNSSVY 60
           M+P  C +  L +     +       E   P  V F++  FH+IL W P       S+ Y
Sbjct: 1   MLP--CLVVLLAALLSLRLGSDAHGTELPSPPSVWFEAEFFHHILHWTP-IPNQSESTCY 57

Query: 61  FVQYKIYGQRQWKNKEDCWGTQELSCDLTSETSDI--QEPYYGRVRAASAGSYSEWSMTP 118
            V    YG   W +  +C  +Q LS DLT+ T D+     Y  RVRA     +S W++T 
Sbjct: 58  EVALLRYGIESWNSISNC--SQTLSYDLTAVTLDLYHSNGYRARVRAVDGSRHSNWTVTN 115

Query: 119 RFTPWWETKIDPPVMNITQVNGSLLVILHAPNLPYRYQKEKNVSIEDYYELLYRVF-IIN 177
                 E  +    +N+   NG +L  +  P       + K     D YE ++  F    
Sbjct: 116 TRFSVDEVTLTVGSVNLEIHNGFILGKIQLP-------RPKMAPANDTYESIFSHFREYE 168

Query: 178 NSLEKEQKVYEGAHRAVEIEALTPHSS-----YCVVAEIYQPMLDRRSQRSEERCVEI 230
            ++ K    +   H+ V+ E  +  +S     +CV  +        +   S+E C+ +
Sbjct: 169 IAIRKVPGNFTFTHKKVKHENFSLLTSGEVGEFCVQVKPSVASRSNKGMWSKEECISL 226


>gi|46488932 interferon-alpha receptor 1 precursor [Homo sapiens]
          Length = 557

 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 43/177 (24%), Positives = 77/177 (43%), Gaps = 9/177 (5%)

Query: 31  PQRVQFQSRNFHNILQWQPGRALTGNSSVYFVQYKIYGQRQWKNKEDCWGTQELSCDLTS 90
           PQ+V+    + + IL+W       GN +  F  Y+  G   W     C       C+ +S
Sbjct: 33  PQKVEVDIIDDNFILRWNRSDESVGNVTFSF-DYQKTGMDNWIKLSGCQNITSTKCNFSS 91

Query: 91  ETSDIQEPYYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQVNGSLLVILHAPN 150
              ++ E    R+RA    + S W     FTP+ + +I PP +++ +     +VI  +P 
Sbjct: 92  LKLNVYEEIKLRIRAEKENT-SSWYEVDSFTPFRKAQIGPPEVHL-EAEDKAIVIHISPG 149

Query: 151 LPYRYQKEKNVSIEDYYELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPHSSYCV 207
                 K+  +   D     Y + I  NS   E+++ E  +   +I  L+P ++YC+
Sbjct: 150 -----TKDSVMWALDGLSFTYSLVIWKNSSGVEERI-ENIYSRHKIYKLSPETTYCL 200



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 49/194 (25%), Positives = 77/194 (39%), Gaps = 26/194 (13%)

Query: 36  FQSRNFHNILQWQPGRALTGNSSVYFVQYKIYGQRQWKNKEDCWGTQELSCDLTSETSDI 95
           FQ +  H  L+  PG  L          YK      WK   DC   +   C         
Sbjct: 257 FQVQWLHAFLKRNPGNHL----------YK------WKQIPDCENVKTTQCVFPQNVFQ- 299

Query: 96  QEPYYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQVNGSLLVILHAPNLPYRY 155
           +  Y  RV+A+   + S WS   +F    +  + PPV NI  ++ S  + + AP      
Sbjct: 300 KGIYLLRVQASDGNNTSFWSEEIKFDTEIQAFLLPPVFNIRSLSDSFHIYIGAP------ 353

Query: 156 QKEKNVSIEDYYELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPHSSYCVVAEIY--Q 213
           ++  N  +   Y L+Y +    N+   E+K+ E     V +  L P + YCV A  +   
Sbjct: 354 KQSGNTPVIQDYPLIYEIIFWENTSNAERKIIE-KKTDVTVPNLKPLTVYCVKARAHTMD 412

Query: 214 PMLDRRSQRSEERC 227
             L++ S  S+  C
Sbjct: 413 EKLNKSSVFSDAVC 426


>gi|4557880 interferon gamma receptor 1 precursor [Homo sapiens]
          Length = 489

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 50/237 (21%), Positives = 100/237 (42%), Gaps = 19/237 (8%)

Query: 10  FLISFFLTGVAGTQSTHESLKPQ------RVQFQSRNFHNILQWQPGRALTGNSSVYFVQ 63
           FL+   + GV+  +     L P        V  +S N + I+ W+    +     V+ V+
Sbjct: 5   FLLPLVMQGVSRAEMGTADLGPSSVPTPTNVTIESYNMNPIVYWE--YQIMPQVPVFTVE 62

Query: 64  YKIYGQRQWKNKEDCWGTQELSCDLTSETSDIQEPYYGRVRAASAGSYSEWSMTPRFTPW 123
            K YG +  +  + C       C+++    D     + RV+A      S ++ +  F   
Sbjct: 63  VKNYGVKNSEWIDACINISHHYCNISDHVGDPSNSLWVRVKARVGQKESAYAKSEEFAVC 122

Query: 124 WETKIDPPVMNITQVNGSLLVILHAPNLPYRYQKEKNVSIE---DYYELLYRVFIINNSL 180
            + KI PP ++I +    +++ +  P++ +    E+ V  +     Y  +Y V++  N  
Sbjct: 123 RDGKIGPPKLDIRKEEKQIMIDIFHPSV-FVNGDEQEVDYDPETTCYIRVYNVYVRMNGS 181

Query: 181 EKEQKVY---EGAHRAVEIEALTP----HSSYCVVAEIYQPMLDRRSQRSEERCVEI 230
           E + K+    E     ++ +   P    +S YCV AE    +    +++S+E C+ I
Sbjct: 182 EIQYKILTQKEDDCDEIQCQLAIPVSSLNSQYCVSAEGVLHVWGVTTEKSKEVCITI 238


>gi|46488937 interferon alpha/beta receptor 2 isoform a precursor
           [Homo sapiens]
          Length = 515

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 48/199 (24%), Positives = 86/199 (43%), Gaps = 19/199 (9%)

Query: 39  RNFHNILQWQPGRALTGNSSV---YFVQYKIYGQRQ-WKNKEDCWGTQELSCDLTSETSD 94
           RNF +IL W+    L  +S V   Y + Y I  + +  K  ++C  T    CDLT E   
Sbjct: 46  RNFRSILSWE----LKNHSIVPTHYTLLYTIMSKPEDLKVVKNCANTTRSFCDLTDEWRS 101

Query: 95  IQEPYYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQVNGSLLVILHAPNL-PY 153
             E Y   V    +G+ + +S +  F    +   +PP   I      + V++  P++   
Sbjct: 102 THEAYV-TVLEGFSGNTTLFSCSHNFWLAIDMSFEPPEFEIVGFTNHINVMVKFPSIVEE 160

Query: 154 RYQKEKNVSIEDYYELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPHSSYCVVAEIYQ 213
             Q + ++ IE+  E + +        + E K     +    I+ L P+++YCV   +Y 
Sbjct: 161 ELQFDLSLVIEEQSEGIVK------KHKPEIKGNMSGNFTYIIDKLIPNTNYCV--SVYL 212

Query: 214 PMLDRRSQ-RSEERCVEIP 231
              D ++  +S  +C  +P
Sbjct: 213 EHSDEQAVIKSPLKCTLLP 231


>gi|46488935 interferon alpha/beta receptor 2 isoform b precursor
           [Homo sapiens]
          Length = 331

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 48/199 (24%), Positives = 86/199 (43%), Gaps = 19/199 (9%)

Query: 39  RNFHNILQWQPGRALTGNSSV---YFVQYKIYGQRQ-WKNKEDCWGTQELSCDLTSETSD 94
           RNF +IL W+    L  +S V   Y + Y I  + +  K  ++C  T    CDLT E   
Sbjct: 46  RNFRSILSWE----LKNHSIVPTHYTLLYTIMSKPEDLKVVKNCANTTRSFCDLTDEWRS 101

Query: 95  IQEPYYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQVNGSLLVILHAPNL-PY 153
             E Y   V    +G+ + +S +  F    +   +PP   I      + V++  P++   
Sbjct: 102 THEAYV-TVLEGFSGNTTLFSCSHNFWLAIDMSFEPPEFEIVGFTNHINVMVKFPSIVEE 160

Query: 154 RYQKEKNVSIEDYYELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPHSSYCVVAEIYQ 213
             Q + ++ IE+  E + +        + E K     +    I+ L P+++YCV   +Y 
Sbjct: 161 ELQFDLSLVIEEQSEGIVK------KHKPEIKGNMSGNFTYIIDKLIPNTNYCV--SVYL 212

Query: 214 PMLDRRSQ-RSEERCVEIP 231
              D ++  +S  +C  +P
Sbjct: 213 EHSDEQAVIKSPLKCTLLP 231


>gi|19923129 interferon alpha/beta receptor 2 isoform b precursor
           [Homo sapiens]
          Length = 331

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 48/199 (24%), Positives = 86/199 (43%), Gaps = 19/199 (9%)

Query: 39  RNFHNILQWQPGRALTGNSSV---YFVQYKIYGQRQ-WKNKEDCWGTQELSCDLTSETSD 94
           RNF +IL W+    L  +S V   Y + Y I  + +  K  ++C  T    CDLT E   
Sbjct: 46  RNFRSILSWE----LKNHSIVPTHYTLLYTIMSKPEDLKVVKNCANTTRSFCDLTDEWRS 101

Query: 95  IQEPYYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQVNGSLLVILHAPNL-PY 153
             E Y   V    +G+ + +S +  F    +   +PP   I      + V++  P++   
Sbjct: 102 THEAYV-TVLEGFSGNTTLFSCSHNFWLAIDMSFEPPEFEIVGFTNHINVMVKFPSIVEE 160

Query: 154 RYQKEKNVSIEDYYELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPHSSYCVVAEIYQ 213
             Q + ++ IE+  E + +        + E K     +    I+ L P+++YCV   +Y 
Sbjct: 161 ELQFDLSLVIEEQSEGIVK------KHKPEIKGNMSGNFTYIIDKLIPNTNYCV--SVYL 212

Query: 214 PMLDRRSQ-RSEERCVEIP 231
              D ++  +S  +C  +P
Sbjct: 213 EHSDEQAVIKSPLKCTLLP 231


>gi|47419934 interferon gamma receptor 2 precursor [Homo sapiens]
          Length = 337

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 34/132 (25%), Positives = 56/132 (42%), Gaps = 15/132 (11%)

Query: 31  PQRVQFQSRNFHNILQWQPGRALTGNSS--VYFVQYKIYGQRQWKNKE------DCWGTQ 82
           PQ  + +  N   +L W+P  AL+ ++   VY VQ+K Y   +W   +      +C    
Sbjct: 33  PQHPKIRLYNAEQVLSWEPV-ALSNSTRPVVYQVQFK-YTDSKWFTADIMSIGVNCTQIT 90

Query: 83  ELSCDLTSETSDIQEPYYG----RVRAASAGSYSEWSMTPRFTPWWETKIDPPV-MNITQ 137
              CD T+ +     P       R+RA     +S W   P F  +    + PP  + +T 
Sbjct: 91  ATECDFTAASPSAGFPMDFNVTLRLRAELGALHSAWVTMPWFQHYRNVTVGPPENIEVTP 150

Query: 138 VNGSLLVILHAP 149
             GSL++   +P
Sbjct: 151 GEGSLIIRFSSP 162


>gi|62632748 killer-cell Ig-like receptor [Homo sapiens]
          Length = 328

 Score = 32.7 bits (73), Expect = 0.27
 Identities = 22/101 (21%), Positives = 48/101 (47%), Gaps = 9/101 (8%)

Query: 99  YYGRVRAASAGSYSEWSMTPRFTPWWETKIDPPVMNITQVNGSLLVILHAPNLPYRYQKE 158
           + G V  A AG+Y      P F   W    +P V+ +T V+    ++ H   L    + E
Sbjct: 81  FIGPVTPAHAGTYRCRGSHPHFLTGWSAPSNPLVIMVTGVHRKPSLLAHPGPL---VKSE 137

Query: 159 KNVSIEDYYELLYRVFII------NNSLEKEQKVYEGAHRA 193
           + V ++ + ++++  F++      N++L    ++++G  +A
Sbjct: 138 ETVILQCWSDVMFEHFLLHREGKFNDTLRLTGELHDGVSKA 178


>gi|4504673 interleukin 6 receptor isoform 1 precursor [Homo
           sapiens]
          Length = 468

 Score = 30.0 bits (66), Expect = 1.7
 Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 4/82 (4%)

Query: 56  NSSVYFVQYKIYGQRQWKNKEDCWGTQELS--CDLTSETSDIQEPYYGRVRAA-SAGSYS 112
           NSS Y +++++  + +       W  ++L   C +    S ++     R +     G +S
Sbjct: 245 NSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304

Query: 113 EWSMTPRFTPWWETKIDPPVMN 134
           EWS     TPW E++  PP  N
Sbjct: 305 EWSPEAMGTPWTESR-SPPAEN 325


>gi|31317249 interleukin 6 receptor isoform 2 precursor [Homo
           sapiens]
          Length = 365

 Score = 30.0 bits (66), Expect = 1.7
 Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 4/82 (4%)

Query: 56  NSSVYFVQYKIYGQRQWKNKEDCWGTQELS--CDLTSETSDIQEPYYGRVRAA-SAGSYS 112
           NSS Y +++++  + +       W  ++L   C +    S ++     R +     G +S
Sbjct: 245 NSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQGEWS 304

Query: 113 EWSMTPRFTPWWETKIDPPVMN 134
           EWS     TPW E++  PP  N
Sbjct: 305 EWSPEAMGTPWTESR-SPPAEN 325


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 28.9 bits (63), Expect = 3.9
 Identities = 13/71 (18%), Positives = 34/71 (47%)

Query: 155 YQKEKNVSIEDYYELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPHSSYCVVAEIYQP 214
           ++KE  + IE+  +L  +   +N  +EK++  +  A +  E+        Y  + ++   
Sbjct: 818 WEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDD 877

Query: 215 MLDRRSQRSEE 225
           + D ++++  E
Sbjct: 878 LEDSKNKQELE 888


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 28.9 bits (63), Expect = 3.9
 Identities = 13/71 (18%), Positives = 34/71 (47%)

Query: 155 YQKEKNVSIEDYYELLYRVFIINNSLEKEQKVYEGAHRAVEIEALTPHSSYCVVAEIYQP 214
           ++KE  + IE+  +L  +   +N  +EK++  +  A +  E+        Y  + ++   
Sbjct: 818 WEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDD 877

Query: 215 MLDRRSQRSEE 225
           + D ++++  E
Sbjct: 878 LEDSKNKQELE 888


>gi|4503993 growth hormone receptor precursor [Homo sapiens]
          Length = 638

 Score = 28.1 bits (61), Expect = 6.6
 Identities = 32/111 (28%), Positives = 52/111 (46%), Gaps = 17/111 (15%)

Query: 70  RQWKNKEDCWGTQELSCDLTSETSDIQEPYYGRVRAASAGSYSE--WSMTPRFTPWWETK 127
           ++WK   D     E SC   S  + I  PY  ++  ++ G+  E  +S+     P     
Sbjct: 96  QEWKECPDYVSAGENSCYFNSSFTSIWIPYCIKL-TSNGGTVDEKCFSVDEIVQP----- 149

Query: 128 IDPPV-MNITQVNGSLLVILHAPNLPYRYQKEKNVSIED-----YYELLYR 172
            DPP+ +N T +N SL  I HA ++  R++  +N  I+       YEL Y+
Sbjct: 150 -DPPIALNWTLLNVSLTGI-HA-DIQVRWEAPRNADIQKGWMVLEYELQYK 197


>gi|22212918 ciliary neurotrophic factor receptor preproprotein
           [Homo sapiens]
          Length = 372

 Score = 28.1 bits (61), Expect = 6.6
 Identities = 17/66 (25%), Positives = 30/66 (45%), Gaps = 3/66 (4%)

Query: 60  YFVQYKIYGQRQWKNKEDCWGTQELSCDLTSETSDIQEPYYGRVRAASAGSYSEWSMTPR 119
           +F++Y+     QW++ E   GT     D  +    I +      +    G++S+WS+   
Sbjct: 242 FFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQV---AAKDNEIGTWSDWSVAAH 298

Query: 120 FTPWWE 125
            TPW E
Sbjct: 299 ATPWTE 304


>gi|4502931 ciliary neurotrophic factor receptor preproprotein [Homo
           sapiens]
          Length = 372

 Score = 28.1 bits (61), Expect = 6.6
 Identities = 17/66 (25%), Positives = 30/66 (45%), Gaps = 3/66 (4%)

Query: 60  YFVQYKIYGQRQWKNKEDCWGTQELSCDLTSETSDIQEPYYGRVRAASAGSYSEWSMTPR 119
           +F++Y+     QW++ E   GT     D  +    I +      +    G++S+WS+   
Sbjct: 242 FFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQV---AAKDNEIGTWSDWSVAAH 298

Query: 120 FTPWWE 125
            TPW E
Sbjct: 299 ATPWTE 304


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,042,508
Number of Sequences: 37866
Number of extensions: 382353
Number of successful extensions: 844
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 811
Number of HSP's gapped (non-prelim): 28
length of query: 231
length of database: 18,247,518
effective HSP length: 99
effective length of query: 132
effective length of database: 14,498,784
effective search space: 1913839488
effective search space used: 1913839488
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.