BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|29826289 cancer susceptibility candidate 4 isoform a [Homo sapiens] (436 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|29826289 cancer susceptibility candidate 4 isoform a [Homo sa... 877 0.0 gi|29826291 cancer susceptibility candidate 4 isoform b [Homo sa... 716 0.0 gi|29550850 golgi membrane protein 1 [Homo sapiens] 127 3e-29 gi|29550838 golgi membrane protein 1 [Homo sapiens] 127 3e-29 gi|239755081 PREDICTED: similar to golgi membrane protein 1 [Hom... 70 4e-12 gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 51 2e-06 gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 49 7e-06 gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 49 7e-06 gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 49 7e-06 gi|65301130 kazrin isoform B [Homo sapiens] 49 7e-06 gi|55770834 centromere protein F [Homo sapiens] 49 7e-06 gi|157837985 kazrin isoform E [Homo sapiens] 48 2e-05 gi|63147424 kazrin isoform A [Homo sapiens] 48 2e-05 gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 48 2e-05 gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 48 2e-05 gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] 47 3e-05 gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] 47 3e-05 gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] 46 8e-05 gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 46 8e-05 gi|5454102 transforming, acidic coiled-coil containing protein 3... 45 1e-04 gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 45 1e-04 gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 44 2e-04 gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa... 44 2e-04 gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap... 44 2e-04 gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 44 3e-04 gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 44 3e-04 gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 44 3e-04 gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 44 3e-04 gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 44 3e-04 gi|46852174 kinesin family member 3A [Homo sapiens] 44 4e-04 >gi|29826289 cancer susceptibility candidate 4 isoform a [Homo sapiens] Length = 436 Score = 877 bits (2267), Expect = 0.0 Identities = 436/436 (100%), Positives = 436/436 (100%) Query: 1 MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR 60 MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR Sbjct: 1 MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR 60 Query: 61 GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQM 120 GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQM Sbjct: 61 GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQM 120 Query: 121 ADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI 180 ADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI Sbjct: 121 ADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI 180 Query: 181 KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGK 240 KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGK Sbjct: 181 KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGK 240 Query: 241 EQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISHLPTGQPLSPNMPP 300 EQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISHLPTGQPLSPNMPP Sbjct: 241 EQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISHLPTGQPLSPNMPP 300 Query: 301 DSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKDRVSDFHKLKQSRF 360 DSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKDRVSDFHKLKQSRF Sbjct: 301 DSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKDRVSDFHKLKQSRF 360 Query: 361 FDENESPVDPQHGSKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEEREL 420 FDENESPVDPQHGSKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEEREL Sbjct: 361 FDENESPVDPQHGSKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEEREL 420 Query: 421 QMDPADYGKQHFNDVL 436 QMDPADYGKQHFNDVL Sbjct: 421 QMDPADYGKQHFNDVL 436 >gi|29826291 cancer susceptibility candidate 4 isoform b [Homo sapiens] Length = 380 Score = 716 bits (1847), Expect = 0.0 Identities = 361/370 (97%), Positives = 364/370 (98%), Gaps = 2/370 (0%) Query: 1 MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR 60 MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR Sbjct: 1 MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR 60 Query: 61 GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQM 120 GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQM Sbjct: 61 GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQM 120 Query: 121 ADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI 180 ADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI Sbjct: 121 ADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI 180 Query: 181 KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGK 240 KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGK Sbjct: 181 KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGK 240 Query: 241 EQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISHLPTGQPLSPNMPP 300 EQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISHLPTGQPLSPNMPP Sbjct: 241 EQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISHLPTGQPLSPNMPP 300 Query: 301 DSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKDRVSDFHKLKQSRF 360 DSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKDRVSDFHKLKQ+ Sbjct: 301 DSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKDRVSDFHKLKQND- 359 Query: 361 FDENESPVDP 370 +E E +DP Sbjct: 360 -EERELQMDP 368 >gi|29550850 golgi membrane protein 1 [Homo sapiens] Length = 401 Score = 127 bits (318), Expect = 3e-29 Identities = 114/431 (26%), Positives = 190/431 (44%), Gaps = 61/431 (14%) Query: 1 MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR 60 M+G G RR+ + P LVL L+ I+VL FNYW SSR V LQ + EL+G+V+R R Sbjct: 1 MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAER 60 Query: 61 GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQM 120 G +E + ++ ++ ++Q+D+ + SS E + K +D+K L NNI+ Sbjct: 61 GAVELKKNEFQGELEKQREQLDKIQ------SSHNFQLESVNKLYQDEKAVLVNNITTGE 114 Query: 121 ADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI 180 I L++QL L++ + R + + ++KN T L ++ Y+ QC QMKE++ Q EE I Sbjct: 115 RLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERI 174 Query: 181 KK--------LADQFLEEQKQETQKIQSNDGKE-----LDINNQVVPKNIPKVAENVADK 227 ++ +A + L E + Q++Q+ + + + VP+ V N + Sbjct: 175 EEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQ 234 Query: 228 NEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISH 287 PSS + K Q+++ E N++ V++ P R P + Q + Sbjct: 235 TPAPSSEVVLDSKRQVEKE--------ETNEIQVVNEEPQRDRLP----QEPGREQVVED 282 Query: 288 LPTGQPLSPNMPPDSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKD 347 P G G G Q P + N + E + ++ ++ Sbjct: 283 RPVGG------------RGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQE 330 Query: 348 RVSDFHKLKQSRFFDENESPVDPQHGSKLA---DYNGDDGNVGEYEADKQAELAYNEEED 404 +E E+ + ++ KL DYN D+ N E E DKQA LA N+ Sbjct: 331 --------------EEQEAAGEGRNQQKLRGEDDYNMDE-NEAESETDKQAALAGNDRNI 375 Query: 405 GDGGEEDVQDD 415 ED + D Sbjct: 376 DVFNVEDQKRD 386 >gi|29550838 golgi membrane protein 1 [Homo sapiens] Length = 401 Score = 127 bits (318), Expect = 3e-29 Identities = 114/431 (26%), Positives = 190/431 (44%), Gaps = 61/431 (14%) Query: 1 MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR 60 M+G G RR+ + P LVL L+ I+VL FNYW SSR V LQ + EL+G+V+R R Sbjct: 1 MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAER 60 Query: 61 GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQM 120 G +E + ++ ++ ++Q+D+ + SS E + K +D+K L NNI+ Sbjct: 61 GAVELKKNEFQGELEKQREQLDKIQ------SSHNFQLESVNKLYQDEKAVLVNNITTGE 114 Query: 121 ADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI 180 I L++QL L++ + R + + ++KN T L ++ Y+ QC QMKE++ Q EE I Sbjct: 115 RLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERI 174 Query: 181 KK--------LADQFLEEQKQETQKIQSNDGKE-----LDINNQVVPKNIPKVAENVADK 227 ++ +A + L E + Q++Q+ + + + VP+ V N + Sbjct: 175 EEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQ 234 Query: 228 NEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISH 287 PSS + K Q+++ E N++ V++ P R P + Q + Sbjct: 235 TPAPSSEVVLDSKRQVEKE--------ETNEIQVVNEEPQRDRLP----QEPGREQVVED 282 Query: 288 LPTGQPLSPNMPPDSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKD 347 P G G G Q P + N + E + ++ ++ Sbjct: 283 RPVGG------------RGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQE 330 Query: 348 RVSDFHKLKQSRFFDENESPVDPQHGSKLA---DYNGDDGNVGEYEADKQAELAYNEEED 404 +E E+ + ++ KL DYN D+ N E E DKQA LA N+ Sbjct: 331 --------------EEQEAAGEGRNQQKLRGEDDYNMDE-NEAESETDKQAALAGNDRNI 375 Query: 405 GDGGEEDVQDD 415 ED + D Sbjct: 376 DVFNVEDQKRD 386 >gi|239755081 PREDICTED: similar to golgi membrane protein 1 [Homo sapiens] Length = 129 Score = 70.1 bits (170), Expect = 4e-12 Identities = 39/111 (35%), Positives = 63/111 (56%), Gaps = 6/111 (5%) Query: 1 MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR 60 M+G G RR+ + P LVL L+ I+VL FNYW SSR V LQ + EL+G+V+R R Sbjct: 1 MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAER 60 Query: 61 GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVK 111 G +E + ++ ++ ++Q+D+ + SS E + K +D+K + Sbjct: 61 GAVELKKNEFQGELEKQREQLDKIQ------SSHNFQLESVNKLYQDEKAR 105 >gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] Length = 1946 Score = 51.2 bits (121), Expect = 2e-06 Identities = 53/212 (25%), Positives = 96/212 (45%), Gaps = 32/212 (15%) Query: 34 SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVD---THKKQIDQKEADYGR 90 S+ RH + +AEL+GQV+ + + +LEK SDL L VD T +Q+ + +A+ + Sbjct: 1203 SLKKRHA---DSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEK 1259 Query: 91 LSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKN 150 L + + R D +L N+++ Q K +L EFLR+ ++ + Sbjct: 1260 LCTLYEERLHEATAKLDKVTQLANDLAAQ-------KTKLWSESGEFLRRLEEKE----- 1307 Query: 151 NTYLVKRLEYESFQCGQQMKELRAQHEENIKKLAD------------QFLEEQKQETQKI 198 L+ +L E +Q+++LR Q E+ K + L EQ +E Q++ Sbjct: 1308 --ALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEV 1365 Query: 199 QSNDGKELDINNQVVPKNIPKVAENVADKNEE 230 ++ + L N + + K NV + E+ Sbjct: 1366 KAELHRTLSKVNAEMVQWRMKYENNVIQRTED 1397 Score = 40.4 bits (93), Expect = 0.003 Identities = 36/157 (22%), Positives = 73/157 (46%), Gaps = 8/157 (5%) Query: 34 SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSS 93 S+S ++ L+++V EL+G +++ AR E+ L + +++ ++ E+ L+ Sbjct: 1031 SLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAE 1090 Query: 94 RLQARE----GLGKRCEDDK---VKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQD 146 L+ +E + + E++K +LQ + I LKE+L R + E + D Sbjct: 1091 ELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERAD 1150 Query: 147 YRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKL 183 ++ L +RLE Q+ E+ + E +KL Sbjct: 1151 LTQDLADLNERLEEVGGSSLAQL-EITKKQETKFQKL 1186 Score = 35.0 bits (79), Expect = 0.13 Identities = 46/220 (20%), Positives = 92/220 (41%), Gaps = 38/220 (17%) Query: 45 EVAELQGQVQRTEVARGRL----EKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREG 100 ++ +L+GQ+++ ++ L +K D LL + ++++ + K A+ R S++ A Sbjct: 1323 QIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVK-AELHRTLSKVNAE-- 1379 Query: 101 LGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEF----------------------L 138 ++K +NN+ + D+ K++LA QE L Sbjct: 1380 ----MVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQL 1435 Query: 139 RQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKI 198 D L D K + RL+ + Q G+ + + + +HEE+ L E Q T+ + Sbjct: 1436 ELGDALSDLGKVRS-AAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELL 1494 Query: 199 QSNDGKELDINNQVV----PKNIPKVAENVADKNEEPSSN 234 + + E I Q KN+ + N+ ++ E + N Sbjct: 1495 KLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKN 1534 Score = 33.1 bits (74), Expect = 0.51 Identities = 41/192 (21%), Positives = 78/192 (40%), Gaps = 33/192 (17%) Query: 42 LQEEVAELQGQVQRTEVARGRLE-------KRNSDLLLLVDTHKKQID------------ 82 L+EE A+LQ ++++E R L+ + +DL+L + ++ + Sbjct: 864 LKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKS 923 Query: 83 --QKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQ 140 Q EA LS R++ E + KL++ +I L+ L + +E Sbjct: 924 KIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTT 983 Query: 141 EDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQS 200 E ++ KN T V+ L + + + K ++ H+ Q L++ E +K+ S Sbjct: 984 EHKV----KNLTEEVEFLNEDISKLNRAAKVVQEAHQ--------QTLDDLHMEEEKLSS 1031 Query: 201 NDGKELDINNQV 212 L + QV Sbjct: 1032 LSKANLKLEQQV 1043 Score = 32.0 bits (71), Expect = 1.1 Identities = 29/123 (23%), Positives = 56/123 (45%), Gaps = 17/123 (13%) Query: 78 KKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEF 137 ++Q+D+ E G L +AR CE + KL+ N+ + +L+ L +E Sbjct: 1040 EQQVDELE---GALEQERKAR----MNCERELHKLEGNLKLNRESMENLESSQRHLAEEL 1092 Query: 138 LRQE---DQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQE 194 ++E Q+ +N LV +L+ + +KEL+ Q ++ +KL + K E Sbjct: 1093 RKKELELSQMNSKVENEKGLVAQLQ-------KTVKELQTQIKDLKEKLEAERTTRAKME 1145 Query: 195 TQK 197 ++ Sbjct: 1146 RER 1148 >gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] Length = 2003 Score = 49.3 bits (116), Expect = 7e-06 Identities = 47/199 (23%), Positives = 91/199 (45%), Gaps = 30/199 (15%) Query: 45 EVAELQGQVQRTEVARGRLEKR---NSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101 EV ELQG+V + E R RL ++ ++L + + ++ ++ + + S L+AR G Sbjct: 899 EVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGE 958 Query: 102 GKRC----EDDKVKLQNNISYQMADIH--------------HLKEQLAELRQEFLRQEDQ 143 + C + +K +LQ +I A + + ++ + ++ L EDQ Sbjct: 959 EEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQ 1018 Query: 144 LQDYRKNNTYLVKRLEYESFQCGQQ------MKELRAQHEENIKKLADQFLEEQK--QET 195 K L RL S Q ++ + +LR ++E I + D+ +E+K QE Sbjct: 1019 NSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQEL 1078 Query: 196 QKIQSN-DGKELDINNQVV 213 +K++ DG+ ++ Q+V Sbjct: 1079 EKLKRRLDGESSELQEQMV 1097 Score = 38.5 bits (88), Expect = 0.012 Identities = 38/185 (20%), Positives = 80/185 (43%), Gaps = 15/185 (8%) Query: 34 SISSRHVLLQEEVAELQGQVQRTEVARGRLEK-------RNSDLLLLVDTHKKQIDQKEA 86 S++ + + +A+++ ++++ E R LEK +S+L + +++ ++ A Sbjct: 1049 SLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRA 1108 Query: 87 DYGRLSSRLQAREGLGKRCEDD---KVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQ 143 GR LQA R ED+ + +L ++ A + +E L R + E Q Sbjct: 1109 QLGRKEEELQAALA---RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1165 Query: 144 LQDYRKNNTYLVKRLE--YESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSN 201 +D + L LE +S Q+++ R Q +KK ++ + Q+++ Sbjct: 1166 RRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQR 1225 Query: 202 DGKEL 206 G+ L Sbjct: 1226 HGQAL 1230 Score = 35.8 bits (81), Expect = 0.078 Identities = 43/225 (19%), Positives = 92/225 (40%), Gaps = 25/225 (11%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQARE-- 99 L+ EV+EL+ ++ + AR E+R L L + + + E + +LQ + Sbjct: 1254 LEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAE 1313 Query: 100 -----GLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYL 154 G E ++L +S A +H +E L E + L + Sbjct: 1314 LENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR----------- 1362 Query: 155 VKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQV-- 212 V+ +E E+ +Q++E A E ++L Q + Q E ++ Q + L+ + Sbjct: 1363 VRAMEAEAAGLREQLEEEAAARERAGREL--QTAQAQLSEWRRRQEEEAGALEAGEEARR 1420 Query: 213 -VPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEE 256 + + + +A+K E + + + G+ ++++ D +E+ Sbjct: 1421 RAAREAEALTQRLAEKTE--TVDRLERGRRRLQQELDDATMDLEQ 1463 Score = 33.5 bits (75), Expect = 0.39 Identities = 50/221 (22%), Positives = 91/221 (41%), Gaps = 30/221 (13%) Query: 48 ELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQ------AREGL 101 +LQG+ + E R +L K+ D + D +KQ A +L L+ A G Sbjct: 1604 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1663 Query: 102 GKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYE 161 GK ++ VK + QM ++ E+ R+E Q + + K V RL+ E Sbjct: 1664 GK---EEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1720 Query: 162 SFQCGQQMKELRAQHEENIKKLAD------QFLEEQKQ----------ETQKIQSNDGKE 205 + ++ + +E ++A+ LEE++Q E ++ QSN Sbjct: 1721 LAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNS--- 1777 Query: 206 LDINNQVVPKNIPKVAENVADKNEEPS-SNHIPHGKEQIKR 245 ++ N K + +V + + E S S G++Q++R Sbjct: 1778 -ELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLER 1817 Score = 32.3 bits (72), Expect = 0.87 Identities = 39/157 (24%), Positives = 70/157 (44%), Gaps = 12/157 (7%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101 LQE++ E Q QR E R +L ++ +L + + D+ A L S +A+ L Sbjct: 1092 LQEQMVEQQ---QRAEELRAQLGRKEEELQAAL---ARAEDEGGARAQLLKSLREAQAAL 1145 Query: 102 GKRCEDDKVK--LQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNN----TYLV 155 + ED + + + Q D+ E L ++ L + Q+ R T L Sbjct: 1146 AEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELK 1205 Query: 156 KRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQK 192 K LE E+ ++ELR +H + + +LA+Q + ++ Sbjct: 1206 KTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARR 1242 >gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] Length = 1995 Score = 49.3 bits (116), Expect = 7e-06 Identities = 47/199 (23%), Positives = 91/199 (45%), Gaps = 30/199 (15%) Query: 45 EVAELQGQVQRTEVARGRLEKR---NSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101 EV ELQG+V + E R RL ++ ++L + + ++ ++ + + S L+AR G Sbjct: 891 EVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGE 950 Query: 102 GKRC----EDDKVKLQNNISYQMADIH--------------HLKEQLAELRQEFLRQEDQ 143 + C + +K +LQ +I A + + ++ + ++ L EDQ Sbjct: 951 EEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQ 1010 Query: 144 LQDYRKNNTYLVKRLEYESFQCGQQ------MKELRAQHEENIKKLADQFLEEQK--QET 195 K L RL S Q ++ + +LR ++E I + D+ +E+K QE Sbjct: 1011 NSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQEL 1070 Query: 196 QKIQSN-DGKELDINNQVV 213 +K++ DG+ ++ Q+V Sbjct: 1071 EKLKRRLDGESSELQEQMV 1089 Score = 38.5 bits (88), Expect = 0.012 Identities = 38/185 (20%), Positives = 80/185 (43%), Gaps = 15/185 (8%) Query: 34 SISSRHVLLQEEVAELQGQVQRTEVARGRLEK-------RNSDLLLLVDTHKKQIDQKEA 86 S++ + + +A+++ ++++ E R LEK +S+L + +++ ++ A Sbjct: 1041 SLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRA 1100 Query: 87 DYGRLSSRLQAREGLGKRCEDD---KVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQ 143 GR LQA R ED+ + +L ++ A + +E L R + E Q Sbjct: 1101 QLGRKEEELQAALA---RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1157 Query: 144 LQDYRKNNTYLVKRLE--YESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSN 201 +D + L LE +S Q+++ R Q +KK ++ + Q+++ Sbjct: 1158 RRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQR 1217 Query: 202 DGKEL 206 G+ L Sbjct: 1218 HGQAL 1222 Score = 35.8 bits (81), Expect = 0.078 Identities = 43/225 (19%), Positives = 92/225 (40%), Gaps = 25/225 (11%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQARE-- 99 L+ EV+EL+ ++ + AR E+R L L + + + E + +LQ + Sbjct: 1246 LEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAE 1305 Query: 100 -----GLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYL 154 G E ++L +S A +H +E L E + L + Sbjct: 1306 LENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR----------- 1354 Query: 155 VKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQV-- 212 V+ +E E+ +Q++E A E ++L Q + Q E ++ Q + L+ + Sbjct: 1355 VRAMEAEAAGLREQLEEEAAARERAGREL--QTAQAQLSEWRRRQEEEAGALEAGEEARR 1412 Query: 213 -VPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEE 256 + + + +A+K E + + + G+ ++++ D +E+ Sbjct: 1413 RAAREAEALTQRLAEKTE--TVDRLERGRRRLQQELDDATMDLEQ 1455 Score = 33.5 bits (75), Expect = 0.39 Identities = 50/221 (22%), Positives = 91/221 (41%), Gaps = 30/221 (13%) Query: 48 ELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQ------AREGL 101 +LQG+ + E R +L K+ D + D +KQ A +L L+ A G Sbjct: 1596 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1655 Query: 102 GKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYE 161 GK ++ VK + QM ++ E+ R+E Q + + K V RL+ E Sbjct: 1656 GK---EEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1712 Query: 162 SFQCGQQMKELRAQHEENIKKLAD------QFLEEQKQ----------ETQKIQSNDGKE 205 + ++ + +E ++A+ LEE++Q E ++ QSN Sbjct: 1713 LAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNS--- 1769 Query: 206 LDINNQVVPKNIPKVAENVADKNEEPS-SNHIPHGKEQIKR 245 ++ N K + +V + + E S S G++Q++R Sbjct: 1770 -ELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLER 1809 Score = 32.3 bits (72), Expect = 0.87 Identities = 39/157 (24%), Positives = 70/157 (44%), Gaps = 12/157 (7%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101 LQE++ E Q QR E R +L ++ +L + + D+ A L S +A+ L Sbjct: 1084 LQEQMVEQQ---QRAEELRAQLGRKEEELQAAL---ARAEDEGGARAQLLKSLREAQAAL 1137 Query: 102 GKRCEDDKVK--LQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNN----TYLV 155 + ED + + + Q D+ E L ++ L + Q+ R T L Sbjct: 1138 AEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELK 1197 Query: 156 KRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQK 192 K LE E+ ++ELR +H + + +LA+Q + ++ Sbjct: 1198 KTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARR 1234 >gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] Length = 2036 Score = 49.3 bits (116), Expect = 7e-06 Identities = 47/199 (23%), Positives = 91/199 (45%), Gaps = 30/199 (15%) Query: 45 EVAELQGQVQRTEVARGRLEKR---NSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101 EV ELQG+V + E R RL ++ ++L + + ++ ++ + + S L+AR G Sbjct: 932 EVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGE 991 Query: 102 GKRC----EDDKVKLQNNISYQMADIH--------------HLKEQLAELRQEFLRQEDQ 143 + C + +K +LQ +I A + + ++ + ++ L EDQ Sbjct: 992 EEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQ 1051 Query: 144 LQDYRKNNTYLVKRLEYESFQCGQQ------MKELRAQHEENIKKLADQFLEEQK--QET 195 K L RL S Q ++ + +LR ++E I + D+ +E+K QE Sbjct: 1052 NSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQEL 1111 Query: 196 QKIQSN-DGKELDINNQVV 213 +K++ DG+ ++ Q+V Sbjct: 1112 EKLKRRLDGESSELQEQMV 1130 Score = 38.5 bits (88), Expect = 0.012 Identities = 38/185 (20%), Positives = 80/185 (43%), Gaps = 15/185 (8%) Query: 34 SISSRHVLLQEEVAELQGQVQRTEVARGRLEK-------RNSDLLLLVDTHKKQIDQKEA 86 S++ + + +A+++ ++++ E R LEK +S+L + +++ ++ A Sbjct: 1082 SLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRA 1141 Query: 87 DYGRLSSRLQAREGLGKRCEDD---KVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQ 143 GR LQA R ED+ + +L ++ A + +E L R + E Q Sbjct: 1142 QLGRKEEELQAALA---RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1198 Query: 144 LQDYRKNNTYLVKRLE--YESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSN 201 +D + L LE +S Q+++ R Q +KK ++ + Q+++ Sbjct: 1199 RRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQR 1258 Query: 202 DGKEL 206 G+ L Sbjct: 1259 HGQAL 1263 Score = 35.8 bits (81), Expect = 0.078 Identities = 43/225 (19%), Positives = 92/225 (40%), Gaps = 25/225 (11%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQARE-- 99 L+ EV+EL+ ++ + AR E+R L L + + + E + +LQ + Sbjct: 1287 LEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAE 1346 Query: 100 -----GLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYL 154 G E ++L +S A +H +E L E + L + Sbjct: 1347 LENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR----------- 1395 Query: 155 VKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQV-- 212 V+ +E E+ +Q++E A E ++L Q + Q E ++ Q + L+ + Sbjct: 1396 VRAMEAEAAGLREQLEEEAAARERAGREL--QTAQAQLSEWRRRQEEEAGALEAGEEARR 1453 Query: 213 -VPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEE 256 + + + +A+K E + + + G+ ++++ D +E+ Sbjct: 1454 RAAREAEALTQRLAEKTE--TVDRLERGRRRLQQELDDATMDLEQ 1496 Score = 33.5 bits (75), Expect = 0.39 Identities = 50/221 (22%), Positives = 91/221 (41%), Gaps = 30/221 (13%) Query: 48 ELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQ------AREGL 101 +LQG+ + E R +L K+ D + D +KQ A +L L+ A G Sbjct: 1637 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1696 Query: 102 GKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYE 161 GK ++ VK + QM ++ E+ R+E Q + + K V RL+ E Sbjct: 1697 GK---EEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1753 Query: 162 SFQCGQQMKELRAQHEENIKKLAD------QFLEEQKQ----------ETQKIQSNDGKE 205 + ++ + +E ++A+ LEE++Q E ++ QSN Sbjct: 1754 LAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNS--- 1810 Query: 206 LDINNQVVPKNIPKVAENVADKNEEPS-SNHIPHGKEQIKR 245 ++ N K + +V + + E S S G++Q++R Sbjct: 1811 -ELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLER 1850 Score = 32.3 bits (72), Expect = 0.87 Identities = 39/157 (24%), Positives = 70/157 (44%), Gaps = 12/157 (7%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101 LQE++ E Q QR E R +L ++ +L + + D+ A L S +A+ L Sbjct: 1125 LQEQMVEQQ---QRAEELRAQLGRKEEELQAAL---ARAEDEGGARAQLLKSLREAQAAL 1178 Query: 102 GKRCEDDKVK--LQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNN----TYLV 155 + ED + + + Q D+ E L ++ L + Q+ R T L Sbjct: 1179 AEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELK 1238 Query: 156 KRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQK 192 K LE E+ ++ELR +H + + +LA+Q + ++ Sbjct: 1239 KTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARR 1275 >gi|65301130 kazrin isoform B [Homo sapiens] Length = 415 Score = 49.3 bits (116), Expect = 7e-06 Identities = 46/150 (30%), Positives = 76/150 (50%), Gaps = 16/150 (10%) Query: 37 SRHVLLQEEVAELQGQV----QRTEVARGRLEK----RNSDLLLLVDTHKKQIDQKEADY 88 S+ VLL+EEV+ LQ +V Q E+ LE+ ++S++L + + Q+ QKE + Sbjct: 67 SQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATEL-RVQLAQKEQEL 125 Query: 89 GRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYR 148 R LQA + KR + +K L + + A + +EQL ++F+R +Q +R Sbjct: 126 ARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQL----RDFIRNYEQ---HR 178 Query: 149 KNNTYLVKRLEYESFQCGQQMKELRAQHEE 178 K + VK L E ++ ELR Q +E Sbjct: 179 KESEDAVKALAKEKDLLEREKWELRRQAKE 208 >gi|55770834 centromere protein F [Homo sapiens] Length = 3114 Score = 49.3 bits (116), Expect = 7e-06 Identities = 51/220 (23%), Positives = 102/220 (46%), Gaps = 13/220 (5%) Query: 35 ISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLL---LLVDTHKKQIDQKEADYGRL 91 I+ + LQ E++GQV + + + +LEK +L+ +++ + ++ + A Y + Sbjct: 294 INELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQA 353 Query: 92 SSRLQAREG-LGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKN 150 S++ A E L K ED + QN S + + +KE+ E ++E RQ+ Q + Sbjct: 354 STKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQE 413 Query: 151 NTYLVKRLEYESFQCGQQMKELRAQHEE--NIKKLADQFLEEQKQE----TQKIQSNDGK 204 + RL E Q L+A+ ++ ++K+ + LEE KQ+ Q Q++ K Sbjct: 414 CIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIK 473 Query: 205 ELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGKEQIK 244 E ++ + K N+ + E + + H + ++K Sbjct: 474 ENELRRSMEEM---KKENNLLKSHSEQKAREVCHLEAELK 510 Score = 39.3 bits (90), Expect = 0.007 Identities = 48/207 (23%), Positives = 87/207 (42%), Gaps = 12/207 (5%) Query: 67 NSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHL 126 NS L+D K Q + L RLQ E K + +LQ + ++ Sbjct: 273 NSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEK 332 Query: 127 KEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLE--YESFQCGQQMKE-LRAQHEENIKKL 183 ++ L + R E +R Q T L ++L+ E C +Q E R E+ IK+ Sbjct: 333 EKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEK 392 Query: 184 ADQFLEEQKQETQKIQSNDGKELDINNQVV-----PKNIPKVAENVADK---NEEPSSNH 235 +F EE ++ + Q+ D + + + ++ KN+ V + DK ++ N+ Sbjct: 393 EKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENN 452 Query: 236 IPHGKEQIKRGGDAGMPG-IEENDLAK 261 + K+++ R A I+EN+L + Sbjct: 453 LEEFKQKLCRAEQAFQASQIKENELRR 479 Score = 37.0 bits (84), Expect = 0.035 Identities = 37/172 (21%), Positives = 73/172 (42%), Gaps = 35/172 (20%) Query: 61 GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCE------------DD 108 G L+K NSDL ++++ D+ L R++ EGL E D+ Sbjct: 1833 GELKKENSDL-------SEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIGDN 1885 Query: 109 KVKLQNNISYQMADIHH----LKEQLAELRQEFLRQEDQLQDYR----------KNNTYL 154 K+ ++ + D+ + ++ + A + E L E L+ + +N + Sbjct: 1886 VAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKV 1945 Query: 155 VKRLEYESFQCGQQMKELRAQHEENIKKLA--DQFLEEQKQETQKIQSNDGK 204 + LE E + +LR + + KK DQ E+ K++TQ+++S+ + Sbjct: 1946 IVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSE 1997 Score = 33.1 bits (74), Expect = 0.51 Identities = 48/234 (20%), Positives = 104/234 (44%), Gaps = 33/234 (14%) Query: 34 SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSS 93 ++SS+ L+ E A+L + + L+ + L+ V+ K+++++K+ + RL + Sbjct: 2470 NLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKN 2529 Query: 94 RLQAREGLGKRCEDDKVKLQNNISYQMADIHHL-KEQLAELRQEFLRQEDQLQDYRKNNT 152 ++Q +E L + Q+ H L KEQ ELR + E ++Q + N Sbjct: 2530 QIQDQEQLVSKLS------------QVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNA 2577 Query: 153 YLVKRLE-----YESFQCGQQMKEL-RAQHEENIKKLA------DQFLEEQKQETQKIQS 200 L LE Y++ + ++ ++ + E + K+ + + E Q+T ++Q Sbjct: 2578 SLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQE 2637 Query: 201 N-DGK------ELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGG 247 G+ EL + + + + ++ E + +E S H K+Q+++ G Sbjct: 2638 ELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMH-KDQVEKEG 2690 Score = 32.0 bits (71), Expect = 1.1 Identities = 19/109 (17%), Positives = 54/109 (49%), Gaps = 7/109 (6%) Query: 44 EEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGK 103 +++ EL+GQ+ + + + + + + L + K++++ ++ + L Q + + Sbjct: 18 QKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICE 77 Query: 104 RCEDDKVKL-------QNNISYQMADIHHLKEQLAELRQEFLRQEDQLQ 145 E K K+ ++ +++Q ++ K+Q+ +L QE R + +L+ Sbjct: 78 SLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELE 126 Score = 30.4 bits (67), Expect = 3.3 Identities = 38/181 (20%), Positives = 74/181 (40%), Gaps = 25/181 (13%) Query: 36 SSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLL---VDTHKKQIDQKEADYGRLS 92 S R LQE+ + Q V T A LE + +L LL V+T + +I + + L Sbjct: 882 SQRISKLQEDTSAHQNVVAETLSA---LENKEKELQLLNDKVETEQAEIQELKKSNHLLE 938 Query: 93 SRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQ--EFLRQEDQLQDYRKN 150 L+ + L + +K ++ + IS +I L ++ L++ L QE Sbjct: 939 DSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQE--------- 989 Query: 151 NTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINN 210 + Q + + E++I +L+DQ+ +E+ Q+ + D++ Sbjct: 990 --------KMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQ 1041 Query: 211 Q 211 + Sbjct: 1042 K 1042 >gi|157837985 kazrin isoform E [Homo sapiens] Length = 775 Score = 48.1 bits (113), Expect = 2e-05 Identities = 45/147 (30%), Positives = 74/147 (50%), Gaps = 16/147 (10%) Query: 40 VLLQEEVAELQGQV----QRTEVARGRLEK----RNSDLLLLVDTHKKQIDQKEADYGRL 91 VLL+EEV+ LQ +V Q E+ LE+ ++S++L + + Q+ QKE + R Sbjct: 76 VLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATEL-RVQLAQKEQELARA 134 Query: 92 SSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNN 151 LQA + KR + +K L + + A + +EQL ++F+R +Q +RK + Sbjct: 135 KEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQL----RDFIRNYEQ---HRKES 187 Query: 152 TYLVKRLEYESFQCGQQMKELRAQHEE 178 VK L E ++ ELR Q +E Sbjct: 188 EDAVKALAKEKDLLEREKWELRRQAKE 214 >gi|63147424 kazrin isoform A [Homo sapiens] Length = 421 Score = 48.1 bits (113), Expect = 2e-05 Identities = 45/147 (30%), Positives = 74/147 (50%), Gaps = 16/147 (10%) Query: 40 VLLQEEVAELQGQV----QRTEVARGRLEK----RNSDLLLLVDTHKKQIDQKEADYGRL 91 VLL+EEV+ LQ +V Q E+ LE+ ++S++L + + Q+ QKE + R Sbjct: 76 VLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATEL-RVQLAQKEQELARA 134 Query: 92 SSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNN 151 LQA + KR + +K L + + A + +EQL ++F+R +Q +RK + Sbjct: 135 KEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQL----RDFIRNYEQ---HRKES 187 Query: 152 TYLVKRLEYESFQCGQQMKELRAQHEE 178 VK L E ++ ELR Q +E Sbjct: 188 EDAVKALAKEKDLLEREKWELRRQAKE 214 >gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 47.8 bits (112), Expect = 2e-05 Identities = 52/250 (20%), Positives = 105/250 (42%), Gaps = 57/250 (22%) Query: 34 SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDL----------LLLVDTHKKQIDQ 83 +++ + L+++V +L+G +++ + R LE+ L ++ ++ K+Q+D+ Sbjct: 1025 TLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDE 1084 Query: 84 ----KEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLR 139 KE + L S+++ + LG ++LQ I A I L+E++ R + Sbjct: 1085 KLKKKEFEISNLQSKIEDEQALG-------IQLQKKIKELQARIEELEEEIEAERASRAK 1137 Query: 140 QEDQLQDYRKNNTYLVKRLEYESFQCGQQMK----------------------------E 171 E Q D + + +RLE Q++ Sbjct: 1138 AEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAT 1197 Query: 172 LRAQHEENIKKLADQF--LEEQKQETQKIQSNDGKELD---INNQVVPK---NIPKVAEN 223 LR +H +++ +L +Q L+ KQ+ +K +S E+D N + V K N+ K+ Sbjct: 1198 LRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRT 1257 Query: 224 VADKNEEPSS 233 + D+ E S Sbjct: 1258 LEDQLSELKS 1267 Score = 42.0 bits (97), Expect = 0.001 Identities = 48/195 (24%), Positives = 89/195 (45%), Gaps = 24/195 (12%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101 LQ EV +L V+RT A L+K+ + ++ K++ ++ A+ L+A + Sbjct: 1427 LQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAE-------LEASQKE 1479 Query: 102 GKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYE 161 + + K++N + + LK + L+QE +Q+ + K + LE Sbjct: 1480 ARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR----IHELEKI 1535 Query: 162 SFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVA 221 Q Q+ EL+A EE A+ LE ++ + +IQ L++ NQV + K+A Sbjct: 1536 KKQVEQEKCELQAALEE-----AEASLEHEEGKILRIQ------LEL-NQVKSEVDRKIA 1583 Query: 222 ENVADKNEEPSSNHI 236 E ++ ++ NHI Sbjct: 1584 EK-DEEIDQLKRNHI 1597 Score = 41.6 bits (96), Expect = 0.001 Identities = 51/202 (25%), Positives = 83/202 (41%), Gaps = 29/202 (14%) Query: 44 EEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGK 103 + VAEL Q+ + + +LEK S++ + +D ++ G L E + + Sbjct: 1204 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNL-------EKMCR 1256 Query: 104 RCEDDKVKLQNNISYQMADIHHLKEQLAELRQ---EFLRQEDQLQDYRKNNTYLVKRLEY 160 ED +L++ Q I+ L Q L+ EF RQ D+ + LV +L Sbjct: 1257 TLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKE-------ALVSQLSR 1309 Query: 161 ESFQCGQQMKELRAQHEENIK---KLAD---------QFLEEQKQETQKIQSNDGKELDI 208 QQ++EL+ Q EE IK LA L EQ +E Q+ ++ + L Sbjct: 1310 GKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSK 1369 Query: 209 NNQVVPKNIPKVAENVADKNEE 230 N V + K + + EE Sbjct: 1370 ANTEVAQWRTKYETDAIQRTEE 1391 Score = 37.0 bits (84), Expect = 0.035 Identities = 48/263 (18%), Positives = 105/263 (39%), Gaps = 29/263 (11%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQ--------------KEAD 87 LQ + EL+ +++ +R + EK+ SDL ++ +++++ +EA+ Sbjct: 1117 LQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAE 1176 Query: 88 YGRLSSRLQ----AREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQ 143 + ++ L+ E + Q+ ++ +K++L + + E + D Sbjct: 1177 FQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDD 1236 Query: 144 LQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSN-- 201 L + + LE Q+ EL+++ EE + + D + + +T+ + + Sbjct: 1237 LASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQ 1296 Query: 202 -DGKE-----LDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIE 255 D KE L Q + I ++ + + E + N + H + + D E Sbjct: 1297 LDEKEALVSQLSRGKQAFTQQIEELKRQL--EEEIKAKNALAHALQSSRHDCDLLREQYE 1354 Query: 256 ENDLAKVDDLPPALRKPPISVSQ 278 E +K +L AL K V+Q Sbjct: 1355 EEQESKA-ELQRALSKANTEVAQ 1376 Score = 33.1 bits (74), Expect = 0.51 Identities = 40/187 (21%), Positives = 75/187 (40%), Gaps = 30/187 (16%) Query: 35 ISSRHVLLQEEVAELQGQVQRTEVAR-----------GRLEKRNSDLLLLVDTHKK---Q 80 + R LLQ E+ EL+ +++TE +R R++ ++ L++T KK Sbjct: 1680 VERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETD 1739 Query: 81 IDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEF--- 137 I Q + + + + E K+ D + + + HL+ + Q Sbjct: 1740 ISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDL 1799 Query: 138 -LRQED-----------QLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLAD 185 LR ++ Q+Q L +E E + + +K LR +HE +K+L Sbjct: 1800 QLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR-KHERRVKELTY 1858 Query: 186 QFLEEQK 192 Q E++K Sbjct: 1859 QTEEDRK 1865 Score = 28.9 bits (63), Expect = 9.6 Identities = 34/188 (18%), Positives = 83/188 (44%), Gaps = 27/188 (14%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEAD-----------YGR 90 +++E ELQ ++ E + E + + L ++ K ++D+K A+ + R Sbjct: 1539 VEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIR 1598 Query: 91 LSSRLQAREGLGKRCEDDKV----KLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQD 146 + +Q+ R +D + K++ +++ ++H AE + + + L+D Sbjct: 1599 IVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKD 1658 Query: 147 YR-------KNNTYLVKRL---EYESFQCGQQMKELRA--QHEENIKKLADQFLEEQKQE 194 + ++ L ++L E + +++ELRA + E +K+A+Q L + + Sbjct: 1659 TQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASER 1718 Query: 195 TQKIQSND 202 Q + + + Sbjct: 1719 VQLLHTQN 1726 >gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo sapiens] Length = 1941 Score = 47.8 bits (112), Expect = 2e-05 Identities = 52/250 (20%), Positives = 105/250 (42%), Gaps = 57/250 (22%) Query: 34 SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDL----------LLLVDTHKKQIDQ 83 +++ + L+++V +L+G +++ + R LE+ L ++ ++ K+Q+D+ Sbjct: 1025 TLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDE 1084 Query: 84 ----KEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLR 139 KE + L S+++ + LG ++LQ I A I L+E++ R + Sbjct: 1085 KLKKKEFEISNLQSKIEDEQALG-------IQLQKKIKELQARIEELEEEIEAERASRAK 1137 Query: 140 QEDQLQDYRKNNTYLVKRLEYESFQCGQQMK----------------------------E 171 E Q D + + +RLE Q++ Sbjct: 1138 AEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAT 1197 Query: 172 LRAQHEENIKKLADQF--LEEQKQETQKIQSNDGKELD---INNQVVPK---NIPKVAEN 223 LR +H +++ +L +Q L+ KQ+ +K +S E+D N + V K N+ K+ Sbjct: 1198 LRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRT 1257 Query: 224 VADKNEEPSS 233 + D+ E S Sbjct: 1258 LEDQLSELKS 1267 Score = 42.0 bits (97), Expect = 0.001 Identities = 48/195 (24%), Positives = 89/195 (45%), Gaps = 24/195 (12%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101 LQ EV +L V+RT A L+K+ + ++ K++ ++ A+ L+A + Sbjct: 1427 LQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAE-------LEASQKE 1479 Query: 102 GKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYE 161 + + K++N + + LK + L+QE +Q+ + K + LE Sbjct: 1480 ARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR----IHELEKI 1535 Query: 162 SFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVA 221 Q Q+ EL+A EE A+ LE ++ + +IQ L++ NQV + K+A Sbjct: 1536 KKQVEQEKCELQAALEE-----AEASLEHEEGKILRIQ------LEL-NQVKSEVDRKIA 1583 Query: 222 ENVADKNEEPSSNHI 236 E ++ ++ NHI Sbjct: 1584 EK-DEEIDQLKRNHI 1597 Score = 41.6 bits (96), Expect = 0.001 Identities = 51/202 (25%), Positives = 83/202 (41%), Gaps = 29/202 (14%) Query: 44 EEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGK 103 + VAEL Q+ + + +LEK S++ + +D ++ G L E + + Sbjct: 1204 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNL-------EKMCR 1256 Query: 104 RCEDDKVKLQNNISYQMADIHHLKEQLAELRQ---EFLRQEDQLQDYRKNNTYLVKRLEY 160 ED +L++ Q I+ L Q L+ EF RQ D+ + LV +L Sbjct: 1257 TLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKE-------ALVSQLSR 1309 Query: 161 ESFQCGQQMKELRAQHEENIK---KLAD---------QFLEEQKQETQKIQSNDGKELDI 208 QQ++EL+ Q EE IK LA L EQ +E Q+ ++ + L Sbjct: 1310 GKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSK 1369 Query: 209 NNQVVPKNIPKVAENVADKNEE 230 N V + K + + EE Sbjct: 1370 ANTEVAQWRTKYETDAIQRTEE 1391 Score = 37.0 bits (84), Expect = 0.035 Identities = 48/263 (18%), Positives = 105/263 (39%), Gaps = 29/263 (11%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQ--------------KEAD 87 LQ + EL+ +++ +R + EK+ SDL ++ +++++ +EA+ Sbjct: 1117 LQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAE 1176 Query: 88 YGRLSSRLQ----AREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQ 143 + ++ L+ E + Q+ ++ +K++L + + E + D Sbjct: 1177 FQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDD 1236 Query: 144 LQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSN-- 201 L + + LE Q+ EL+++ EE + + D + + +T+ + + Sbjct: 1237 LASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQ 1296 Query: 202 -DGKE-----LDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIE 255 D KE L Q + I ++ + + E + N + H + + D E Sbjct: 1297 LDEKEALVSQLSRGKQAFTQQIEELKRQL--EEEIKAKNALAHALQSSRHDCDLLREQYE 1354 Query: 256 ENDLAKVDDLPPALRKPPISVSQ 278 E +K +L AL K V+Q Sbjct: 1355 EEQESKA-ELQRALSKANTEVAQ 1376 Score = 33.1 bits (74), Expect = 0.51 Identities = 40/187 (21%), Positives = 75/187 (40%), Gaps = 30/187 (16%) Query: 35 ISSRHVLLQEEVAELQGQVQRTEVAR-----------GRLEKRNSDLLLLVDTHKK---Q 80 + R LLQ E+ EL+ +++TE +R R++ ++ L++T KK Sbjct: 1680 VERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETD 1739 Query: 81 IDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEF--- 137 I Q + + + + E K+ D + + + HL+ + Q Sbjct: 1740 ISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDL 1799 Query: 138 -LRQED-----------QLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLAD 185 LR ++ Q+Q L +E E + + +K LR +HE +K+L Sbjct: 1800 QLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR-KHERRVKELTY 1858 Query: 186 QFLEEQK 192 Q E++K Sbjct: 1859 QTEEDRK 1865 Score = 28.9 bits (63), Expect = 9.6 Identities = 34/188 (18%), Positives = 83/188 (44%), Gaps = 27/188 (14%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEAD-----------YGR 90 +++E ELQ ++ E + E + + L ++ K ++D+K A+ + R Sbjct: 1539 VEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIR 1598 Query: 91 LSSRLQAREGLGKRCEDDKV----KLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQD 146 + +Q+ R +D + K++ +++ ++H AE + + + L+D Sbjct: 1599 IVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKD 1658 Query: 147 YR-------KNNTYLVKRL---EYESFQCGQQMKELRA--QHEENIKKLADQFLEEQKQE 194 + ++ L ++L E + +++ELRA + E +K+A+Q L + + Sbjct: 1659 TQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASER 1718 Query: 195 TQKIQSND 202 Q + + + Sbjct: 1719 VQLLHTQN 1726 >gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] Length = 971 Score = 47.0 bits (110), Expect = 3e-05 Identities = 45/186 (24%), Positives = 84/186 (45%), Gaps = 26/186 (13%) Query: 42 LQEEVAELQGQVQRT-EVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREG 100 L+E+ +LQ +++ EV +L N ++ L D +K L + EG Sbjct: 403 LEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKS-----------EQGLGSAEG 451 Query: 101 LGKRCEDDKVKLQNNISYQMADIHHLKEQL----AELRQE---------FLRQEDQLQDY 147 L +D + +LQN + + K+ L EL QE +++E++L+ Sbjct: 452 LIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVD 511 Query: 148 RKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKEL- 206 + + +K E +C + +ELR QHEE+ K Q L+ + +E + + K++ Sbjct: 512 KMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVE 571 Query: 207 DINNQV 212 D+ NQ+ Sbjct: 572 DLLNQI 577 Score = 31.6 bits (70), Expect = 1.5 Identities = 27/129 (20%), Positives = 58/129 (44%), Gaps = 8/129 (6%) Query: 57 EVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNI 116 E+A ++E S +D ++Q + L L+ RE + + L NI Sbjct: 723 ELAAAKMELERS-----IDISRRQSKEHICRITDLQEELRHREHHISELDKEVQHLHENI 777 Query: 117 SYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQH 176 S ++ +++ +R E Q+ +L++ + YL++ + E Q ++K + + Sbjct: 778 SALTKELEFKGKEILRIRSES-NQQIRLEEMEEK--YLMRESKPEDIQMITELKAMLTER 834 Query: 177 EENIKKLAD 185 ++ IKKL + Sbjct: 835 DQIIKKLIE 843 >gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] Length = 1140 Score = 47.0 bits (110), Expect = 3e-05 Identities = 45/186 (24%), Positives = 84/186 (45%), Gaps = 26/186 (13%) Query: 42 LQEEVAELQGQVQRT-EVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREG 100 L+E+ +LQ +++ EV +L N ++ L D +K L + EG Sbjct: 523 LEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKS-----------EQGLGSAEG 571 Query: 101 LGKRCEDDKVKLQNNISYQMADIHHLKEQL----AELRQE---------FLRQEDQLQDY 147 L +D + +LQN + + K+ L EL QE +++E++L+ Sbjct: 572 LIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVD 631 Query: 148 RKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKEL- 206 + + +K E +C + +ELR QHEE+ K Q L+ + +E + + K++ Sbjct: 632 KMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVE 691 Query: 207 DINNQV 212 D+ NQ+ Sbjct: 692 DLLNQI 697 Score = 29.6 bits (65), Expect = 5.6 Identities = 29/149 (19%), Positives = 67/149 (44%), Gaps = 14/149 (9%) Query: 46 VAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRC 105 + +LQ +++ E L+K L + K+++ K + R+ S ++ + + Sbjct: 869 ITDLQEELRHREHHISELDKEVQHLHENISALTKELEFKGKEILRIRS--ESNQQIRLHE 926 Query: 106 EDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRK---------NNTYLVK 156 +D +L+ + AD HL+E+ +R +F + + L++ YL++ Sbjct: 927 QDLNKRLEKELDVMTAD--HLREKNI-MRADFNKTNELLKEINAALQVSLEEMEEKYLMR 983 Query: 157 RLEYESFQCGQQMKELRAQHEENIKKLAD 185 + E Q ++K + + ++ IKKL + Sbjct: 984 ESKPEDIQMITELKAMLTERDQIIKKLIE 1012 >gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] Length = 495 Score = 45.8 bits (107), Expect = 8e-05 Identities = 46/205 (22%), Positives = 96/205 (46%), Gaps = 16/205 (7%) Query: 41 LLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQARE- 99 + +E+ E Q ++++ R +E+ + L +++++++ ++ Q RE Sbjct: 223 IYEEDQLEKQQKLEKMNAMRRYIEEFQKEQALWRKKKREEMEEENRKIIEFANMQQQREE 282 Query: 100 ---GLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKN-----N 151 + E+ +++LQN ++ ++ ++ +E L ++RQE L QE+Q + Y+ Sbjct: 283 DRMAKVQENEEKRLQLQNALTQKLEEMLRQREDLEQVRQE-LYQEEQAEIYKSKLKEEAE 341 Query: 152 TYLVKRLEY-ESFQCGQQMKELRAQ----HEENIKK-LADQFLEEQKQETQKIQSNDGKE 205 L K+ E + F+ +KEL Q EEN +K + +F E+ + E Q K+ Sbjct: 342 KKLRKQKEMKQDFEEQMALKELVLQAAKEEEENFRKTMLAKFAEDDRIELMNAQKQRMKQ 401 Query: 206 LDINNQVVPKNIPKVAENVADKNEE 230 L+ V + + +ADK E Sbjct: 402 LEHRRAVEKLIEERRQQFLADKQRE 426 >gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1 [Homo sapiens] Length = 3259 Score = 45.8 bits (107), Expect = 8e-05 Identities = 46/196 (23%), Positives = 90/196 (45%), Gaps = 20/196 (10%) Query: 47 AELQGQVQRTEVARGRLEKRNSDLLL-------LVDTHKKQIDQKEADYGRLSSRLQARE 99 ++ Q +VQ + L+ N +LL L + + ++ + E++ L +L Sbjct: 2266 SKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLS 2325 Query: 100 GLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLE 159 ++C++ K L+ I Q ADI + K +L + Q + R + +K + Sbjct: 2326 NSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDL--QASRELTSRLHEEINMKEQK 2383 Query: 160 YESFQCGQQ------MKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQVV 213 S G++ + ELR QH++ IK+L + L ++++E ++ + K +D NQ++ Sbjct: 2384 IISLLSGKEEAIQVAIAELRQQHDKEIKEL-ENLLSQEEEENIVLEEENKKAVDKTNQLM 2442 Query: 214 P--KNIPKVAENVADK 227 K I K EN+ K Sbjct: 2443 ETLKTIKK--ENIQQK 2456 Score = 39.7 bits (91), Expect = 0.005 Identities = 50/214 (23%), Positives = 95/214 (44%), Gaps = 27/214 (12%) Query: 41 LLQEEVAELQGQVQRTEVARGRLEKRNS----DLLLLVDTHKKQIDQKEADYGRLSSRLQ 96 LL++E + + ++Q + R L +R S +L L D KK+I E + G + + Sbjct: 983 LLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKE 1042 Query: 97 AREGLGK----RCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNT 152 +E K +C++ ++ L+ IS + ++ H+++ L +E L E+Q Q Sbjct: 1043 NKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDL----EEKLAAEEQFQ------- 1091 Query: 153 YLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQV 212 LVK++ Q+ L+A+ EN + QK T ++DG + + + Sbjct: 1092 ALVKQMNQTLQDKTNQIDLLQAEISENQAII-------QKLITSNTDASDGDSVALVKET 1144 Query: 213 VPKNIPKVAENVADKNE-EPSSNHIPHGKEQIKR 245 V + P + K E E + KEQ+++ Sbjct: 1145 VVISPPCTGSSEHWKPELEEKILALEKEKEQLQK 1178 Score = 37.4 bits (85), Expect = 0.027 Identities = 47/220 (21%), Positives = 100/220 (45%), Gaps = 20/220 (9%) Query: 26 VVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQK- 84 V L S +S EEV +LQ Q+ + + L+ + + + H + + QK Sbjct: 1319 VELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHE----AEVHAESLQQKL 1374 Query: 85 EADYGRLSSRLQAREGLGKRCEDDKV--KLQNNISYQMADIHHLKEQLAELRQEFLRQED 142 E+ +++ RE K E K+ K + ++SY + + L +++ E + QED Sbjct: 1375 ESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQED 1434 Query: 143 -------QLQDYRKNNTYLVKRLEYESFQCGQQMKEL--RAQHEENIKKLADQFLEEQKQ 193 QL+ K + +K+L+ E + Q+ +E+ ++ ++ I++ L +K+ Sbjct: 1435 LIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKE 1494 Query: 194 ETQKIQSNDGKELDINNQVV---PKNIPKVAENVADKNEE 230 ++ +S +EL + + K++ V V+ +N+E Sbjct: 1495 ALKENKSLQ-EELSLARGTIERLTKSLADVESQVSAQNKE 1533 Score = 37.4 bits (85), Expect = 0.027 Identities = 42/226 (18%), Positives = 102/226 (45%), Gaps = 39/226 (17%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLL--LVDTHKKQIDQKEADYGRLSSRLQARE 99 LQEE +L +++ +V+ +L ++ + L + + Q+ KE + RLS+ + + Sbjct: 2593 LQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQ 2652 Query: 100 GLGKRCEDDKV-----------KLQNNISYQMADIHH-----------LKEQLAELRQEF 137 E++ V ++++ + ++ +HH +E++AEL ++ Sbjct: 2653 KRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDL 2712 Query: 138 LRQEDQLQDYRKNNTYLVKRLE-----YESFQ-----CGQQMKELRAQHEENIKKLADQF 187 + E +L K N L +++ S Q +++ EL+ +++ ++K+LA Sbjct: 2713 VEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQ-- 2770 Query: 188 LEEQ---KQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEE 230 L+EQ +E + S ++ + ++ K+ + + K+E+ Sbjct: 2771 LKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQ 2816 Score = 37.0 bits (84), Expect = 0.035 Identities = 86/434 (19%), Positives = 166/434 (38%), Gaps = 76/434 (17%) Query: 34 SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVD--THKKQIDQKEADYGRL 91 ++ R LLQEE +L ++ R+ + L L L ++ T K+ KE + + Sbjct: 1536 TVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKS 1595 Query: 92 SSRLQAREGLGKRCEDDK---VKLQN--NISYQMADIHHLKE------------------ 128 S ++ E K E K + LQ+ N+S + I H+ E Sbjct: 1596 SKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEA 1655 Query: 129 -------QLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYE--------------SFQCGQ 167 QL E QE +++++ + K+ + LE E + +C + Sbjct: 1656 NKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECME 1715 Query: 168 QMKELRAQHEENIKKLADQF--LEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVA 225 + A +E ++++ ++ L ++ Q + + +E+ + N+ K A A Sbjct: 1716 TLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEA 1775 Query: 226 DKNEEPSSNHIPHGKEQIKRGGDAGMPG-IEENDLAKV-------DDLPPALRKPPISVS 277 + + +N G + I PG EE D + + +P A P Sbjct: 1776 TEKHDNQTNVTEEGTQSI--------PGETEEQDSLSMSTRPTCSESVPSAKSANPAVSK 1827 Query: 278 QHESHQAI-SHLPTGQPLSPNMPP-DSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPR 335 SH I ++L L + + N + +N + L I S D E + Sbjct: 1828 DFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQI--STKDGELK 1885 Query: 336 I------QTDILKQATKDRVSDFHKLKQSRFFDENESPVDPQHGSKLADYNGDDGNVGEY 389 + + ++L Q ++ +S KLK++ +E + ++ + ++LA+ NG GN + Sbjct: 1886 MLQEEVTKMNLLNQQIQEELSRVTKLKETA--EEEKDDLEERLMNQLAELNGSIGNYCQD 1943 Query: 390 EADKQAELAYNEEE 403 D Q + E E Sbjct: 1944 VTDAQIKNELLESE 1957 Score = 36.6 bits (83), Expect = 0.046 Identities = 43/203 (21%), Positives = 89/203 (43%), Gaps = 34/203 (16%) Query: 43 QEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAR---- 98 +E + E + + +ARG +E+ L + Q +K+ GRL+ + R Sbjct: 1493 KEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLI 1552 Query: 99 ----------EGLGKRCE----------DDKVKLQNNI----SYQMADIHHLKEQLAELR 134 + L CE +DK KL I S ++A+ +E+ EL+ Sbjct: 1553 TEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQ 1612 Query: 135 QEF---LRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKL--ADQFLE 189 +E+ L+ + + + + ++V+ + E + +++ A +E K+L A+Q +E Sbjct: 1613 KEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEME 1672 Query: 190 EQKQETQKI-QSNDGKELDINNQ 211 E K++ +K +S K L++ + Sbjct: 1673 EMKEKMRKFAKSKQQKILELEEE 1695 Score = 32.0 bits (71), Expect = 1.1 Identities = 28/139 (20%), Positives = 61/139 (43%), Gaps = 7/139 (5%) Query: 69 DLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMAD----IH 124 +L L+ ++++ Q + D R ++ A E K E + + Q ++ + + Sbjct: 2009 ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVE 2068 Query: 125 HLKEQLAELRQEFLRQEDQLQDYRK---NNTYLVKRLEYESFQCGQQMKELRAQHEENIK 181 H K+ AEL + +D + + +N L K L+ QMK+ E ++ Sbjct: 2069 HRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLE 2128 Query: 182 KLADQFLEEQKQETQKIQS 200 + ++ L+E+K +K+ + Sbjct: 2129 QAEEKHLKEKKNMQEKLDA 2147 Score = 30.4 bits (67), Expect = 3.3 Identities = 19/75 (25%), Positives = 38/75 (50%), Gaps = 6/75 (8%) Query: 71 LLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQL 130 +L ++ K+Q+ +K L L +R+ + K+ ++ + L+ + Q D + L+EQ Sbjct: 1166 ILALEKEKEQLQKK------LQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQF 1219 Query: 131 AELRQEFLRQEDQLQ 145 E +E DQL+ Sbjct: 1220 DEQSKENENIGDQLR 1234 Score = 30.4 bits (67), Expect = 3.3 Identities = 40/185 (21%), Positives = 73/185 (39%), Gaps = 22/185 (11%) Query: 44 EEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGK 103 +EV +LQ + T K S L D + ID+ + + S +Q++E + Sbjct: 2171 KEVQQLQENLDSTVTQLAAFTKSMSSLQ---DDRDRVIDEAKKWERKFSDAIQSKEEEIR 2227 Query: 104 RCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESF 163 ED+ L++ + + LK ++ L + E + Q + + L+ E+ Sbjct: 2228 LKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENK 2287 Query: 164 QCGQQMKELR----------AQHEENIKKLADQFLEEQKQETQKIQSNDG--------KE 205 + Q++E R A+ E +K L DQ L + +K + G +E Sbjct: 2288 ELLSQLEETRHLYHSSQNELAKLESELKSLKDQ-LTDLSNSLEKCKEQKGNLEGIIRQQE 2346 Query: 206 LDINN 210 DI N Sbjct: 2347 ADIQN 2351 >gi|5454102 transforming, acidic coiled-coil containing protein 3 [Homo sapiens] Length = 838 Score = 45.4 bits (106), Expect = 1e-04 Identities = 50/205 (24%), Positives = 97/205 (47%), Gaps = 32/205 (15%) Query: 41 LLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRL----- 95 LLQ +L V+ T+ L R +L H K ++ G++ R Sbjct: 636 LLQYSQKDLDAVVKATQEENRELRSRCEEL------HGKNLE-----LGKIMDRFEEVVY 684 Query: 96 QAREGLGKRCEDDKVKLQNNISYQ---MADIHHLKEQLAELRQEFLRQEDQLQDYRKNNT 152 QA E + K+ E K ++Q + + D++ +++ ++L + F +Q++ ++ YRKN Sbjct: 685 QAMEEVQKQKELSKAEIQKVLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEVIEGYRKNEE 744 Query: 153 YLVKRLE---YESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQ----KIQSNDGKE 205 L K +E Q GQ+ + L+A EE + +LA++ + + + + Q +Q++ KE Sbjct: 745 SLKKCVEDYLARITQEGQRYQALKAHAEEKL-QLANEEIAQVRSKAQAEALALQASLRKE 803 Query: 206 LDINNQVVPKNIPKVAENVADKNEE 230 Q+ +++ K E +NEE Sbjct: 804 -----QMRIQSLEKTVEQKTKENEE 823 >gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo sapiens] Length = 1939 Score = 45.1 bits (105), Expect = 1e-04 Identities = 54/247 (21%), Positives = 104/247 (42%), Gaps = 57/247 (23%) Query: 34 SISSRHVLLQEEVAELQGQVQRTEVARGRLE----KRNSDLLLL------VDTHKKQIDQ 83 +++ + L+++V +L+G +++ + R LE K DL L ++ K+Q+D+ Sbjct: 1023 TLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDE 1082 Query: 84 ----KEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLR 139 KE + L S+++ + LG ++LQ I A I L+E++ R + Sbjct: 1083 KLKKKEFEMSGLQSKIEDEQALG-------MQLQKKIKELQARIEELEEEIEAERASRAK 1135 Query: 140 QEDQLQDYRKNNTYLVKRLEYESFQCGQQMK----------------------------E 171 E Q D + + +RLE Q++ Sbjct: 1136 AEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAT 1195 Query: 172 LRAQHEENIKKLADQF--LEEQKQETQKIQSNDGKELD---INNQVVPK---NIPKVAEN 223 LR +H +++ +L +Q L+ KQ+ +K +S E+D N + V K N+ K+ Sbjct: 1196 LRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRA 1255 Query: 224 VADKNEE 230 + D+ E Sbjct: 1256 LEDQLSE 1262 Score = 44.3 bits (103), Expect = 2e-04 Identities = 48/195 (24%), Positives = 89/195 (45%), Gaps = 24/195 (12%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101 LQ EV +L V+RT A L+K+ + ++ K++ ++ A+ L+A + Sbjct: 1425 LQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAE-------LEASQKE 1477 Query: 102 GKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYE 161 + + K++N + + LK + L+QE +Q+ + K + LE Sbjct: 1478 SRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR----IHELEKI 1533 Query: 162 SFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVA 221 Q Q+ EL+A EE A+ LE ++ + +IQ L++ NQV + K+A Sbjct: 1534 KKQVEQEKSELQAALEE-----AEASLEHEEGKILRIQ------LEL-NQVKSEVDRKIA 1581 Query: 222 ENVADKNEEPSSNHI 236 E ++ ++ NHI Sbjct: 1582 EK-DEEIDQMKRNHI 1595 Score = 42.0 bits (97), Expect = 0.001 Identities = 47/182 (25%), Positives = 74/182 (40%), Gaps = 30/182 (16%) Query: 44 EEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGK 103 + VAEL Q+ + + +LEK S++ K +ID ++ +S E + + Sbjct: 1202 DSVAELGEQIDNLQRVKQKLEKEKSEM-------KMEIDDLASNMETVSKAKGNLEKMCR 1254 Query: 104 RCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESF 163 ED +++ Q I+ L Q A L+ E QL + LV +L Sbjct: 1255 ALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDE----KDTLVSQLSRGKQ 1310 Query: 164 QCGQQMKELRAQHEENIKK-----------------LADQFLEEQ--KQETQKIQSNDGK 204 QQ++EL+ Q EE IK L +Q+ EEQ K E Q+ S Sbjct: 1311 AFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANS 1370 Query: 205 EL 206 E+ Sbjct: 1371 EV 1372 Score = 35.0 bits (79), Expect = 0.13 Identities = 40/172 (23%), Positives = 82/172 (47%), Gaps = 21/172 (12%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101 LQ + EL+ +++ +R + EK+ SDL ++I ++ + G +S A+ + Sbjct: 1115 LQARIEELEEEIEAERASRAKAEKQRSDL----SRELEEISERLEEAGGATS---AQIEM 1167 Query: 102 GKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYE 161 K+ E + K++ ++ + A + H + A LR++ +L + N + ++LE E Sbjct: 1168 NKKREAEFQKMRRDL--EEATLQH-EATAATLRKKHADSVAELGEQIDNLQRVKQKLEKE 1224 Query: 162 SFQCGQQMKELRAQHEE------NIKK----LADQFLE-EQKQETQKIQSND 202 + ++ +L + E N++K L DQ E + K+E Q+ ND Sbjct: 1225 KSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLIND 1276 Score = 32.7 bits (73), Expect = 0.66 Identities = 47/218 (21%), Positives = 88/218 (40%), Gaps = 51/218 (23%) Query: 35 ISSRHVLLQEEVAELQGQVQRTEVAR-----------GRLEKRNSDLLLLVDTHKK---Q 80 + R LLQ E+ EL+ +++TE +R R++ ++ L++T KK Sbjct: 1678 VERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETD 1737 Query: 81 IDQKEADYGRLSSRLQAREGLGKRCEDDKV-----------------KLQNNISYQMADI 123 I Q + + + + E K+ D +++ N+ + D+ Sbjct: 1738 ISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDL 1797 Query: 124 HHL------------KEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKE 171 H K+Q+ +L E +++ +K N VK L +++KE Sbjct: 1798 QHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHE----RKVKE 1853 Query: 172 LRAQHEE---NIKKLADQFLEEQ-KQETQKIQSNDGKE 205 L Q EE NI +L D + Q K ++ K Q+ + +E Sbjct: 1854 LTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEE 1891 Score = 28.9 bits (63), Expect = 9.6 Identities = 34/188 (18%), Positives = 84/188 (44%), Gaps = 27/188 (14%) Query: 42 LQEEVAELQGQVQRTEVA-----------RGRLEKRNSDLLLLVDTHKKQIDQKEADYGR 90 +++E +ELQ ++ E + + L + S++ + ++IDQ + ++ R Sbjct: 1537 VEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIR 1596 Query: 91 LSSRLQAREGLGKRCEDD----KVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQD 146 + +Q+ R +D K K++ +++ ++H AE + + + L+D Sbjct: 1597 IVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKD 1656 Query: 147 YR-------KNNTYLVKRL---EYESFQCGQQMKELRA--QHEENIKKLADQFLEEQKQE 194 + ++ L ++L E + +++ELRA + E +K+A+Q L + + Sbjct: 1657 TQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASER 1716 Query: 195 TQKIQSND 202 Q + + + Sbjct: 1717 VQLLHTQN 1724 >gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] Length = 1960 Score = 44.3 bits (103), Expect = 2e-04 Identities = 36/167 (21%), Positives = 74/167 (44%), Gaps = 19/167 (11%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHK-------KQIDQKEADYGRLSSR 94 L +++AELQ Q+ ++ + E+ L V+ K+I + E+ L Sbjct: 1060 LSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQED 1119 Query: 95 LQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYL 154 L++ + E K L ++ LK +L + Q++ + L Sbjct: 1120 LESERASRNKAEKQKRDLGE-------ELEALKTELEDTLDSTAAQQELRSKREQEVNIL 1172 Query: 155 VKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSN 201 K LE E+ Q++E+R +H + +++LA EQ ++T+++++N Sbjct: 1173 KKTLEEEAKTHEAQIQEMRQKHSQAVEELA-----EQLEQTKRVKAN 1214 Score = 43.5 bits (101), Expect = 4e-04 Identities = 40/184 (21%), Positives = 83/184 (45%), Gaps = 24/184 (13%) Query: 26 VVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKE 85 ++L ++ LL++ +AE + E +++ L L + H+ I E Sbjct: 981 IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEE-------EKSKSLAKLKNKHEAMITDLE 1033 Query: 86 ADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQ 145 R + Q E ++ E D L + I+ L+ Q+AEL+ + ++E++LQ Sbjct: 1034 ERLRREEKQRQELEKTRRKLEGDSTDLSDQIA-------ELQAQIAELKMQLAKKEEELQ 1086 Query: 146 DYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQ--KQETQKIQSNDG 203 + R+E E+ Q +K++R + E I +L + E+ + + +K + + G Sbjct: 1087 -------AALARVEEEAAQKNMALKKIR-ELESQISELQEDLESERASRNKAEKQKRDLG 1138 Query: 204 KELD 207 +EL+ Sbjct: 1139 EELE 1142 Score = 40.0 bits (92), Expect = 0.004 Identities = 39/194 (20%), Positives = 89/194 (45%), Gaps = 27/194 (13%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101 L+E +L+ +V+ E L+ + + ++Q++++E+ +L E Sbjct: 913 LEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAK 972 Query: 102 GKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYE 161 K+ E++++ L+ +Q +L +E ED++ ++ N T E Sbjct: 973 LKKLEEEQIILE--------------DQNCKLAKEKKLLEDRIAEFTTNLT--------E 1010 Query: 162 SFQCGQQMKELRAQHEENIKKLADQFL--EEQKQETQKIQSN-DGKELDINNQV--VPKN 216 + + + +L+ +HE I L ++ E+Q+QE +K + +G D+++Q+ + Sbjct: 1011 EEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ 1070 Query: 217 IPKVAENVADKNEE 230 I ++ +A K EE Sbjct: 1071 IAELKMQLAKKEEE 1084 Score = 38.9 bits (89), Expect = 0.009 Identities = 32/192 (16%), Positives = 84/192 (43%), Gaps = 5/192 (2%) Query: 44 EEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGK 103 +++ +LQ Q++ ++L ++K++ EA+ +L L A E + Sbjct: 1638 KQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKR 1697 Query: 104 RCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESF 163 + + ++ +L + I+ E+ L + E++L++ + N + RL+ + Sbjct: 1698 QAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANL 1757 Query: 164 QCGQ-----QMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIP 218 Q Q ++ AQ EN ++ ++ +E K + Q+++ + + + I Sbjct: 1758 QIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIA 1817 Query: 219 KVAENVADKNEE 230 ++ E + ++ +E Sbjct: 1818 QLEEQLDNETKE 1829 Score = 34.3 bits (77), Expect = 0.23 Identities = 34/174 (19%), Positives = 71/174 (40%), Gaps = 5/174 (2%) Query: 41 LLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREG 100 LL EE + + A ++ + L L ++ ++QK A+ RL+ + + Sbjct: 1449 LLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQK-AELERLNKQFRTEME 1507 Query: 101 LGKRCEDDKVK----LQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVK 156 +DD K L+ + + +K QL EL E ED N + Sbjct: 1508 DLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKA 1567 Query: 157 RLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINN 210 + E + +Q +E + Q ++++ + +E+KQ + + + E+D+ + Sbjct: 1568 QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKD 1621 Score = 33.9 bits (76), Expect = 0.30 Identities = 40/224 (17%), Positives = 94/224 (41%), Gaps = 29/224 (12%) Query: 34 SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQK--------- 84 S+S++ +++E + Q++ E A+ LEK+ + L V KK+++ Sbjct: 1326 SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEE 1385 Query: 85 -----EADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQ---- 135 + D LS R + + + E K +LQ + + D+ H ++ L + Sbjct: 1386 VKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKK 1445 Query: 136 --EFLRQEDQLQ----DYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLE 189 + L +E + + R + E ++ + ++E Q E +++L QF Sbjct: 1446 FDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAE-LERLNKQFRT 1504 Query: 190 EQKQETQKIQSNDGK---ELDINNQVVPKNIPKVAENVADKNEE 230 E ++ + + GK EL+ + + + + + ++ + + +E Sbjct: 1505 EM-EDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDE 1547 Score = 30.0 bits (66), Expect = 4.3 Identities = 25/112 (22%), Positives = 47/112 (41%), Gaps = 14/112 (12%) Query: 42 LQEEVAELQGQVQRTEVARG-------RLEKRNSDLLLLVD-------THKKQIDQKEAD 87 L+ ++A+L+ Q+ R R EK+ D+LL VD +K Q D+ Sbjct: 1812 LEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTR 1871 Query: 88 YGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLR 139 +L +L+ E +R + KLQ + + +++ L+ + R Sbjct: 1872 LKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRR 1923 Score = 28.9 bits (63), Expect = 9.6 Identities = 50/219 (22%), Positives = 87/219 (39%), Gaps = 34/219 (15%) Query: 38 RHVLLQEEVAELQGQVQRT----EVARGRLEKRNSDLLLLVDT---------HKKQIDQK 84 +H EE+AE Q +R E A+ LE +L V HK++ + Sbjct: 1193 KHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRK--KV 1250 Query: 85 EADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQL 144 EA L + E + D KLQ + + + ++L ++F E QL Sbjct: 1251 EAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQL 1310 Query: 145 QD-----YRKNNTYL-----VKRLEYESFQCGQQM-KELRAQH--EENIKKLADQFLEEQ 191 QD +N L +K++E E +Q+ +E A+H E+ I L Q + + Sbjct: 1311 QDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMK 1370 Query: 192 KQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEE 230 K+ + + E V + + K E ++ ++EE Sbjct: 1371 KKMEDSVGCLETAE------EVKRKLQKDLEGLSQRHEE 1403 >gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sapiens] Length = 1185 Score = 44.3 bits (103), Expect = 2e-04 Identities = 50/194 (25%), Positives = 83/194 (42%), Gaps = 22/194 (11%) Query: 34 SISSRHVLLQEEVAE-LQGQVQRTEVARGRLEKRNSDLLLLVDTH--KKQIDQKEADYGR 90 S+ H L E+V E L+ ++R + L + +L++L + + KK + D Sbjct: 166 SLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGVLDINH 225 Query: 91 LSSRLQAREGLGKRCEDDK----------VKLQNNISYQMADIHHLKEQLAELRQEFLRQ 140 + G KR D ++LQ IS Q + +KE+LA L Sbjct: 226 EQENTPSTSG--KRSSDGSLSHEEDLAKVIELQEIISKQSREQSQMKERLASLSSHVTEL 283 Query: 141 EDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQH---EENIKKLADQFLEEQKQETQK 197 E+ L RK+ L+K E + + + ++E AQ EE I L ++L Q++ T Sbjct: 284 EEDLDTARKD---LIKSEEMNT-KLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSV 339 Query: 198 IQSNDGKELDINNQ 211 ND E +I N+ Sbjct: 340 HDLNDKLENEIANK 353 >gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sapiens] Length = 1202 Score = 44.3 bits (103), Expect = 2e-04 Identities = 50/194 (25%), Positives = 83/194 (42%), Gaps = 22/194 (11%) Query: 34 SISSRHVLLQEEVAE-LQGQVQRTEVARGRLEKRNSDLLLLVDTH--KKQIDQKEADYGR 90 S+ H L E+V E L+ ++R + L + +L++L + + KK + D Sbjct: 166 SLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGVLDINH 225 Query: 91 LSSRLQAREGLGKRCEDDK----------VKLQNNISYQMADIHHLKEQLAELRQEFLRQ 140 + G KR D ++LQ IS Q + +KE+LA L Sbjct: 226 EQENTPSTSG--KRSSDGSLSHEEDLAKVIELQEIISKQSREQSQMKERLASLSSHVTEL 283 Query: 141 EDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQH---EENIKKLADQFLEEQKQETQK 197 E+ L RK+ L+K E + + + ++E AQ EE I L ++L Q++ T Sbjct: 284 EEDLDTARKD---LIKSEEMNT-KLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSV 339 Query: 198 IQSNDGKELDINNQ 211 ND E +I N+ Sbjct: 340 HDLNDKLENEIANK 353 >gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo sapiens] Length = 1940 Score = 43.9 bits (102), Expect = 3e-04 Identities = 48/209 (22%), Positives = 89/209 (42%), Gaps = 44/209 (21%) Query: 34 SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDL----------LLLVDTHKKQIDQ 83 S++ L+++V +L+ +++ + R LE+ L +L ++ K+Q+D+ Sbjct: 1020 SLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDE 1079 Query: 84 ----KEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLR 139 K+ +Y +L S+++ + LG ++ Q I A I L+E++ R + Sbjct: 1080 RLKKKDFEYCQLQSKVEDEQTLG-------LQFQKKIKELQARIEELEEEIEAERATRAK 1132 Query: 140 QEDQLQDYRKNNTYLVKRL-----------------EYESFQCGQQMKELRAQHEENI-- 180 E Q DY + L +RL E E + + ++E QHE + Sbjct: 1133 TEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAA 1192 Query: 181 --KKLADQFLE--EQKQETQKIQSNDGKE 205 KK AD E EQ Q+++ KE Sbjct: 1193 LRKKHADSVAELGEQIDNLQRVKQKLEKE 1221 Score = 39.3 bits (90), Expect = 0.007 Identities = 48/210 (22%), Positives = 87/210 (41%), Gaps = 27/210 (12%) Query: 44 EEVAELQGQVQRTEVARGRLEKRNSDLLLLVD---THKKQIDQKEADYGRLSSRL--QAR 98 + VAEL Q+ + + +LEK S+ L +D + + + + +A+ ++ L Q Sbjct: 1199 DSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLS 1258 Query: 99 EGLGKRCE---------DDKVKLQ---NNISYQMADIHHLKEQLAELRQEFLRQED---- 142 E GK E K +LQ +S Q+ + + QL+ +Q F +Q + Sbjct: 1259 EARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKR 1318 Query: 143 QLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSND 202 QL++ K L L+ C LR Q+EE + A+ K ++ Q Sbjct: 1319 QLEEENKAKNALAHALQSSRHDCDL----LREQYEEEQEGKAELQRALSKANSEVAQWRT 1374 Query: 203 GKELDI--NNQVVPKNIPKVAENVADKNEE 230 E D + + + K+A+ + D E+ Sbjct: 1375 KYETDAIQRTEELEEAKKKLAQRLQDSEEQ 1404 Score = 38.1 bits (87), Expect = 0.016 Identities = 48/212 (22%), Positives = 100/212 (47%), Gaps = 34/212 (16%) Query: 35 ISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSR 94 + R LLQ EV EL+ +++TE AR E+ L+D++ ++ + + + +S Sbjct: 1675 VERRANLLQAEVEELRATLEQTERARKLAEQE------LLDSN----ERVQLLHTQNTSL 1724 Query: 95 LQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQ-------LAELRQEFLRQED---QL 144 + + K+ E D ++LQ+ + D + +E+ A + +E +++D L Sbjct: 1725 IHTK----KKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHL 1780 Query: 145 QDYRKNNTYLVKRLEYESFQCGQQM----KELRAQHEENIKKLADQFLEEQKQETQKIQ- 199 + +KN VK L++ + Q K+ + E I++L + EQK+ T+ ++ Sbjct: 1781 ERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKG 1840 Query: 200 ----SNDGKELDINNQVVPKNIPKVAENVADK 227 KEL ++ KN+ ++ +++ DK Sbjct: 1841 LRKYERRVKELTYQSEEDRKNVLRL-QDLVDK 1871 Score = 35.4 bits (80), Expect = 0.10 Identities = 36/176 (20%), Positives = 70/176 (39%), Gaps = 23/176 (13%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101 LQ EV +L V+R L+K+ + ++ K + ++ +A+ L+A Sbjct: 1422 LQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAE-------LEASLKE 1474 Query: 102 GKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVK----- 156 + + KL+N + + +K + L QE +Q+ + K L K Sbjct: 1475 SRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQI 1534 Query: 157 RLEYESFQCGQQMKELRAQHEE-----------NIKKLADQFLEEQKQETQKIQSN 201 LE Q + E +HEE +K D+ + E+ +E ++++ N Sbjct: 1535 ELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRN 1590 >gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo sapiens] Length = 1972 Score = 43.9 bits (102), Expect = 3e-04 Identities = 43/175 (24%), Positives = 84/175 (48%), Gaps = 17/175 (9%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQI-------DQKEADYGRLSSR 94 L++E+ + Q + R LE+R SDL + +++ ++ E+ L R Sbjct: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042 Query: 95 LQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYL 154 L+ E + E K KL+ + S I L+ Q+AEL+ + ++E++LQ Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ-------AA 1095 Query: 155 VKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQ--KQETQKIQSNDGKELD 207 + RL+ E Q +K++R + E +I L + E+ + + +K + + G+EL+ Sbjct: 1096 LARLDDEIAQKNNALKKIR-ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1149 Score = 40.0 bits (92), Expect = 0.004 Identities = 57/222 (25%), Positives = 96/222 (43%), Gaps = 34/222 (15%) Query: 38 RHVLLQEEVAELQGQVQRTEVARGR----LEKRNSDL---LLLVDTHKKQIDQKEADYGR 90 +H EE+ E Q +R + + LEK N+DL L ++ K++++ K+ Sbjct: 1200 KHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA 1259 Query: 91 LSSRLQAREGLGKRCE---DDKV-KLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQD 146 LQ++ G+R +DKV KLQN + ++ + + +L ++ QLQD Sbjct: 1260 QVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQD 1319 Query: 147 YRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQE--------TQKI 198 + + L+ E+ Q +LR Q EE L DQ EE + + T I Sbjct: 1320 TQ-------ELLQEETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNLERHISTLNI 1371 Query: 199 QSNDGKE--LDINNQVV-----PKNIPKVAENVADKNEEPSS 233 Q +D K+ D + V K K EN+ + EE ++ Sbjct: 1372 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAA 1413 Score = 35.0 bits (79), Expect = 0.13 Identities = 44/210 (20%), Positives = 96/210 (45%), Gaps = 29/210 (13%) Query: 34 SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQID----------- 82 ++S++ L+EE LQ Q+ A+ LE+ S L + + KK++ Sbjct: 1333 NVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1392 Query: 83 -----QKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEF 137 QKE + L+ + + + + E K +LQ + + D+ + ++ ++ L ++ Sbjct: 1393 GKKRFQKEIE--NLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK- 1449 Query: 138 LRQEDQLQDYRKN--NTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLE--EQKQ 193 R+ DQL KN + Y +R E+ ++ K L ++ + ++ LE E+ + Sbjct: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKAL------SLARALEEALEAKEELE 1503 Query: 194 ETQKIQSNDGKELDINNQVVPKNIPKVAEN 223 T K+ + ++L + V KN+ ++ ++ Sbjct: 1504 RTNKMLKAEMEDLVSSKDDVGKNVHELEKS 1533 Score = 34.7 bits (78), Expect = 0.17 Identities = 36/175 (20%), Positives = 70/175 (40%), Gaps = 8/175 (4%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101 L+ ++ +L+ Q R K+ L + +++++ A + + + E Sbjct: 1622 LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK 1681 Query: 102 GKRCEDDKVKLQNNISY-----QMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVK 156 K E D ++LQ +++ + AD+ KE+LAE L + LQD ++ + Sbjct: 1682 AKSLEADLMQLQEDLAAAERARKQADLE--KEELAEELASSLSGRNALQDEKRRLEARIA 1739 Query: 157 RLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQ 211 +LE E + Q E + + A+Q E E Q N+ + Q Sbjct: 1740 QLE-EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1793 >gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo sapiens] Length = 1979 Score = 43.9 bits (102), Expect = 3e-04 Identities = 43/175 (24%), Positives = 84/175 (48%), Gaps = 17/175 (9%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQI-------DQKEADYGRLSSR 94 L++E+ + Q + R LE+R SDL + +++ ++ E+ L R Sbjct: 990 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1049 Query: 95 LQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYL 154 L+ E + E K KL+ + S I L+ Q+AEL+ + ++E++LQ Sbjct: 1050 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ-------AA 1102 Query: 155 VKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQ--KQETQKIQSNDGKELD 207 + RL+ E Q +K++R + E +I L + E+ + + +K + + G+EL+ Sbjct: 1103 LARLDDEIAQKNNALKKIR-ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1156 Score = 40.0 bits (92), Expect = 0.004 Identities = 57/222 (25%), Positives = 96/222 (43%), Gaps = 34/222 (15%) Query: 38 RHVLLQEEVAELQGQVQRTEVARGR----LEKRNSDL---LLLVDTHKKQIDQKEADYGR 90 +H EE+ E Q +R + + LEK N+DL L ++ K++++ K+ Sbjct: 1207 KHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA 1266 Query: 91 LSSRLQAREGLGKRCE---DDKV-KLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQD 146 LQ++ G+R +DKV KLQN + ++ + + +L ++ QLQD Sbjct: 1267 QVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQD 1326 Query: 147 YRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQE--------TQKI 198 + + L+ E+ Q +LR Q EE L DQ EE + + T I Sbjct: 1327 TQ-------ELLQEETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNLERHISTLNI 1378 Query: 199 QSNDGKE--LDINNQVV-----PKNIPKVAENVADKNEEPSS 233 Q +D K+ D + V K K EN+ + EE ++ Sbjct: 1379 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAA 1420 Score = 35.0 bits (79), Expect = 0.13 Identities = 44/210 (20%), Positives = 96/210 (45%), Gaps = 29/210 (13%) Query: 34 SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQID----------- 82 ++S++ L+EE LQ Q+ A+ LE+ S L + + KK++ Sbjct: 1340 NVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1399 Query: 83 -----QKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEF 137 QKE + L+ + + + + E K +LQ + + D+ + ++ ++ L ++ Sbjct: 1400 GKKRFQKEIE--NLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK- 1456 Query: 138 LRQEDQLQDYRKN--NTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLE--EQKQ 193 R+ DQL KN + Y +R E+ ++ K L ++ + ++ LE E+ + Sbjct: 1457 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKAL------SLARALEEALEAKEELE 1510 Query: 194 ETQKIQSNDGKELDINNQVVPKNIPKVAEN 223 T K+ + ++L + V KN+ ++ ++ Sbjct: 1511 RTNKMLKAEMEDLVSSKDDVGKNVHELEKS 1540 Score = 34.7 bits (78), Expect = 0.17 Identities = 36/175 (20%), Positives = 70/175 (40%), Gaps = 8/175 (4%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101 L+ ++ +L+ Q R K+ L + +++++ A + + + E Sbjct: 1629 LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK 1688 Query: 102 GKRCEDDKVKLQNNISY-----QMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVK 156 K E D ++LQ +++ + AD+ KE+LAE L + LQD ++ + Sbjct: 1689 AKSLEADLMQLQEDLAAAERARKQADLE--KEELAEELASSLSGRNALQDEKRRLEARIA 1746 Query: 157 RLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQ 211 +LE E + Q E + + A+Q E E Q N+ + Q Sbjct: 1747 QLE-EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1800 >gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo sapiens] Length = 1945 Score = 43.9 bits (102), Expect = 3e-04 Identities = 43/175 (24%), Positives = 84/175 (48%), Gaps = 17/175 (9%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQI-------DQKEADYGRLSSR 94 L++E+ + Q + R LE+R SDL + +++ ++ E+ L R Sbjct: 990 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1049 Query: 95 LQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYL 154 L+ E + E K KL+ + S I L+ Q+AEL+ + ++E++LQ Sbjct: 1050 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ-------AA 1102 Query: 155 VKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQ--KQETQKIQSNDGKELD 207 + RL+ E Q +K++R + E +I L + E+ + + +K + + G+EL+ Sbjct: 1103 LARLDDEIAQKNNALKKIR-ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1156 Score = 40.0 bits (92), Expect = 0.004 Identities = 57/222 (25%), Positives = 96/222 (43%), Gaps = 34/222 (15%) Query: 38 RHVLLQEEVAELQGQVQRTEVARGR----LEKRNSDL---LLLVDTHKKQIDQKEADYGR 90 +H EE+ E Q +R + + LEK N+DL L ++ K++++ K+ Sbjct: 1207 KHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA 1266 Query: 91 LSSRLQAREGLGKRCE---DDKV-KLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQD 146 LQ++ G+R +DKV KLQN + ++ + + +L ++ QLQD Sbjct: 1267 QVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQD 1326 Query: 147 YRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQE--------TQKI 198 + + L+ E+ Q +LR Q EE L DQ EE + + T I Sbjct: 1327 TQ-------ELLQEETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNLERHISTLNI 1378 Query: 199 QSNDGKE--LDINNQVV-----PKNIPKVAENVADKNEEPSS 233 Q +D K+ D + V K K EN+ + EE ++ Sbjct: 1379 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAA 1420 Score = 35.0 bits (79), Expect = 0.13 Identities = 44/210 (20%), Positives = 96/210 (45%), Gaps = 29/210 (13%) Query: 34 SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQID----------- 82 ++S++ L+EE LQ Q+ A+ LE+ S L + + KK++ Sbjct: 1340 NVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1399 Query: 83 -----QKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEF 137 QKE + L+ + + + + E K +LQ + + D+ + ++ ++ L ++ Sbjct: 1400 GKKRFQKEIE--NLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK- 1456 Query: 138 LRQEDQLQDYRKN--NTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLE--EQKQ 193 R+ DQL KN + Y +R E+ ++ K L ++ + ++ LE E+ + Sbjct: 1457 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKAL------SLARALEEALEAKEELE 1510 Query: 194 ETQKIQSNDGKELDINNQVVPKNIPKVAEN 223 T K+ + ++L + V KN+ ++ ++ Sbjct: 1511 RTNKMLKAEMEDLVSSKDDVGKNVHELEKS 1540 Score = 34.7 bits (78), Expect = 0.17 Identities = 36/175 (20%), Positives = 70/175 (40%), Gaps = 8/175 (4%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101 L+ ++ +L+ Q R K+ L + +++++ A + + + E Sbjct: 1629 LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK 1688 Query: 102 GKRCEDDKVKLQNNISY-----QMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVK 156 K E D ++LQ +++ + AD+ KE+LAE L + LQD ++ + Sbjct: 1689 AKSLEADLMQLQEDLAAAERARKQADLE--KEELAEELASSLSGRNALQDEKRRLEARIA 1746 Query: 157 RLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQ 211 +LE E + Q E + + A+Q E E Q N+ + Q Sbjct: 1747 QLE-EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1800 >gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo sapiens] Length = 1938 Score = 43.9 bits (102), Expect = 3e-04 Identities = 43/175 (24%), Positives = 84/175 (48%), Gaps = 17/175 (9%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQI-------DQKEADYGRLSSR 94 L++E+ + Q + R LE+R SDL + +++ ++ E+ L R Sbjct: 983 LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042 Query: 95 LQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYL 154 L+ E + E K KL+ + S I L+ Q+AEL+ + ++E++LQ Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ-------AA 1095 Query: 155 VKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQ--KQETQKIQSNDGKELD 207 + RL+ E Q +K++R + E +I L + E+ + + +K + + G+EL+ Sbjct: 1096 LARLDDEIAQKNNALKKIR-ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1149 Score = 40.0 bits (92), Expect = 0.004 Identities = 57/222 (25%), Positives = 96/222 (43%), Gaps = 34/222 (15%) Query: 38 RHVLLQEEVAELQGQVQRTEVARGR----LEKRNSDL---LLLVDTHKKQIDQKEADYGR 90 +H EE+ E Q +R + + LEK N+DL L ++ K++++ K+ Sbjct: 1200 KHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA 1259 Query: 91 LSSRLQAREGLGKRCE---DDKV-KLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQD 146 LQ++ G+R +DKV KLQN + ++ + + +L ++ QLQD Sbjct: 1260 QVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQD 1319 Query: 147 YRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQE--------TQKI 198 + + L+ E+ Q +LR Q EE L DQ EE + + T I Sbjct: 1320 TQ-------ELLQEETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNLERHISTLNI 1371 Query: 199 QSNDGKE--LDINNQVV-----PKNIPKVAENVADKNEEPSS 233 Q +D K+ D + V K K EN+ + EE ++ Sbjct: 1372 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAA 1413 Score = 35.0 bits (79), Expect = 0.13 Identities = 44/210 (20%), Positives = 96/210 (45%), Gaps = 29/210 (13%) Query: 34 SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQID----------- 82 ++S++ L+EE LQ Q+ A+ LE+ S L + + KK++ Sbjct: 1333 NVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1392 Query: 83 -----QKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEF 137 QKE + L+ + + + + E K +LQ + + D+ + ++ ++ L ++ Sbjct: 1393 GKKRFQKEIE--NLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK- 1449 Query: 138 LRQEDQLQDYRKN--NTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLE--EQKQ 193 R+ DQL KN + Y +R E+ ++ K L ++ + ++ LE E+ + Sbjct: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKAL------SLARALEEALEAKEELE 1503 Query: 194 ETQKIQSNDGKELDINNQVVPKNIPKVAEN 223 T K+ + ++L + V KN+ ++ ++ Sbjct: 1504 RTNKMLKAEMEDLVSSKDDVGKNVHELEKS 1533 Score = 34.7 bits (78), Expect = 0.17 Identities = 36/175 (20%), Positives = 70/175 (40%), Gaps = 8/175 (4%) Query: 42 LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101 L+ ++ +L+ Q R K+ L + +++++ A + + + E Sbjct: 1622 LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK 1681 Query: 102 GKRCEDDKVKLQNNISY-----QMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVK 156 K E D ++LQ +++ + AD+ KE+LAE L + LQD ++ + Sbjct: 1682 AKSLEADLMQLQEDLAAAERARKQADLE--KEELAEELASSLSGRNALQDEKRRLEARIA 1739 Query: 157 RLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQ 211 +LE E + Q E + + A+Q E E Q N+ + Q Sbjct: 1740 QLE-EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1793 >gi|46852174 kinesin family member 3A [Homo sapiens] Length = 699 Score = 43.5 bits (101), Expect = 4e-04 Identities = 52/234 (22%), Positives = 104/234 (44%), Gaps = 28/234 (11%) Query: 48 ELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCED 107 +L + + AR LEKR DLL H+ +++ A ++ + + L K E Sbjct: 436 KLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVI--VGGVDLLAKAEEQ 493 Query: 108 DKVKLQNNISYQ--MADIHHLKEQLAELRQEFLRQEDQ---LQDYRKNNTYLVKRLEYES 162 +K+ ++N+ + L+ +L E QE L E++ LQ+ + T +K++ Sbjct: 494 EKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTML 553 Query: 163 FQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAE 222 +M +L+ +H+ I+ L LE +Q +++++ ++ I + +P++ ++ E Sbjct: 554 MAAKSEMADLQQEHQREIEGL----LENIRQLSRELR----LQMLIIDNFIPRDYQEMIE 605 Query: 223 NVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISV 276 N NE+ G+ Q+K G N++ K +P K P V Sbjct: 606 NYVHWNED-------IGEWQLKCVAYTG------NNMRKQTPVPDKKEKDPFEV 646 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.131 0.368 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,015,260 Number of Sequences: 37866 Number of extensions: 946455 Number of successful extensions: 7625 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 160 Number of HSP's successfully gapped in prelim test: 644 Number of HSP's that attempted gapping in prelim test: 5452 Number of HSP's gapped (non-prelim): 2272 length of query: 436 length of database: 18,247,518 effective HSP length: 105 effective length of query: 331 effective length of database: 14,271,588 effective search space: 4723895628 effective search space used: 4723895628 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.