Guide to the Human Genome
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Search of human proteins with 29826289

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|29826289 cancer susceptibility candidate 4 isoform a [Homo
sapiens]
         (436 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|29826289 cancer susceptibility candidate 4 isoform a [Homo sa...   877   0.0  
gi|29826291 cancer susceptibility candidate 4 isoform b [Homo sa...   716   0.0  
gi|29550850 golgi membrane protein 1 [Homo sapiens]                   127   3e-29
gi|29550838 golgi membrane protein 1 [Homo sapiens]                   127   3e-29
gi|239755081 PREDICTED: similar to golgi membrane protein 1 [Hom...    70   4e-12
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]               51   2e-06
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]           49   7e-06
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]           49   7e-06
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]           49   7e-06
gi|65301130 kazrin isoform B [Homo sapiens]                            49   7e-06
gi|55770834 centromere protein F [Homo sapiens]                        49   7e-06
gi|157837985 kazrin isoform E [Homo sapiens]                           48   2e-05
gi|63147424 kazrin isoform A [Homo sapiens]                            48   2e-05
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...    48   2e-05
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...    48   2e-05
gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]    47   3e-05
gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]    47   3e-05
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]        46   8e-05
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    46   8e-05
gi|5454102 transforming, acidic coiled-coil containing protein 3...    45   1e-04
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...    45   1e-04
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     44   2e-04
gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa...    44   2e-04
gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap...    44   2e-04
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    44   3e-04
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    44   3e-04
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    44   3e-04
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    44   3e-04
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    44   3e-04
gi|46852174 kinesin family member 3A [Homo sapiens]                    44   4e-04

>gi|29826289 cancer susceptibility candidate 4 isoform a [Homo
           sapiens]
          Length = 436

 Score =  877 bits (2267), Expect = 0.0
 Identities = 436/436 (100%), Positives = 436/436 (100%)

Query: 1   MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR 60
           MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR
Sbjct: 1   MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR 60

Query: 61  GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQM 120
           GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQM
Sbjct: 61  GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQM 120

Query: 121 ADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI 180
           ADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI
Sbjct: 121 ADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI 180

Query: 181 KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGK 240
           KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGK
Sbjct: 181 KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGK 240

Query: 241 EQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISHLPTGQPLSPNMPP 300
           EQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISHLPTGQPLSPNMPP
Sbjct: 241 EQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISHLPTGQPLSPNMPP 300

Query: 301 DSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKDRVSDFHKLKQSRF 360
           DSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKDRVSDFHKLKQSRF
Sbjct: 301 DSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKDRVSDFHKLKQSRF 360

Query: 361 FDENESPVDPQHGSKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEEREL 420
           FDENESPVDPQHGSKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEEREL
Sbjct: 361 FDENESPVDPQHGSKLADYNGDDGNVGEYEADKQAELAYNEEEDGDGGEEDVQDDEEREL 420

Query: 421 QMDPADYGKQHFNDVL 436
           QMDPADYGKQHFNDVL
Sbjct: 421 QMDPADYGKQHFNDVL 436


>gi|29826291 cancer susceptibility candidate 4 isoform b [Homo
           sapiens]
          Length = 380

 Score =  716 bits (1847), Expect = 0.0
 Identities = 361/370 (97%), Positives = 364/370 (98%), Gaps = 2/370 (0%)

Query: 1   MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR 60
           MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR
Sbjct: 1   MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR 60

Query: 61  GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQM 120
           GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQM
Sbjct: 61  GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQM 120

Query: 121 ADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI 180
           ADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI
Sbjct: 121 ADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI 180

Query: 181 KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGK 240
           KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGK
Sbjct: 181 KKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGK 240

Query: 241 EQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISHLPTGQPLSPNMPP 300
           EQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISHLPTGQPLSPNMPP
Sbjct: 241 EQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISHLPTGQPLSPNMPP 300

Query: 301 DSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKDRVSDFHKLKQSRF 360
           DSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKDRVSDFHKLKQ+  
Sbjct: 301 DSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKDRVSDFHKLKQND- 359

Query: 361 FDENESPVDP 370
            +E E  +DP
Sbjct: 360 -EERELQMDP 368


>gi|29550850 golgi membrane protein 1 [Homo sapiens]
          Length = 401

 Score =  127 bits (318), Expect = 3e-29
 Identities = 114/431 (26%), Positives = 190/431 (44%), Gaps = 61/431 (14%)

Query: 1   MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR 60
           M+G G  RR+ + P LVL  L+  I+VL FNYW  SSR V LQ  + EL+G+V+R    R
Sbjct: 1   MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAER 60

Query: 61  GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQM 120
           G +E + ++    ++  ++Q+D+ +      SS     E + K  +D+K  L NNI+   
Sbjct: 61  GAVELKKNEFQGELEKQREQLDKIQ------SSHNFQLESVNKLYQDEKAVLVNNITTGE 114

Query: 121 ADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI 180
             I  L++QL  L++ + R +  +  ++KN T L ++  Y+  QC  QMKE++ Q EE I
Sbjct: 115 RLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERI 174

Query: 181 KK--------LADQFLEEQKQETQKIQSNDGKE-----LDINNQVVPKNIPKVAENVADK 227
           ++        +A + L E   + Q++Q+    +       + +  VP+    V  N   +
Sbjct: 175 EEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQ 234

Query: 228 NEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISH 287
              PSS  +   K Q+++         E N++  V++ P   R P     +    Q +  
Sbjct: 235 TPAPSSEVVLDSKRQVEKE--------ETNEIQVVNEEPQRDRLP----QEPGREQVVED 282

Query: 288 LPTGQPLSPNMPPDSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKD 347
            P G                G  G   Q P       +   N + E   +  ++    ++
Sbjct: 283 RPVGG------------RGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQE 330

Query: 348 RVSDFHKLKQSRFFDENESPVDPQHGSKLA---DYNGDDGNVGEYEADKQAELAYNEEED 404
                         +E E+  + ++  KL    DYN D+ N  E E DKQA LA N+   
Sbjct: 331 --------------EEQEAAGEGRNQQKLRGEDDYNMDE-NEAESETDKQAALAGNDRNI 375

Query: 405 GDGGEEDVQDD 415
                ED + D
Sbjct: 376 DVFNVEDQKRD 386


>gi|29550838 golgi membrane protein 1 [Homo sapiens]
          Length = 401

 Score =  127 bits (318), Expect = 3e-29
 Identities = 114/431 (26%), Positives = 190/431 (44%), Gaps = 61/431 (14%)

Query: 1   MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR 60
           M+G G  RR+ + P LVL  L+  I+VL FNYW  SSR V LQ  + EL+G+V+R    R
Sbjct: 1   MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAER 60

Query: 61  GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQM 120
           G +E + ++    ++  ++Q+D+ +      SS     E + K  +D+K  L NNI+   
Sbjct: 61  GAVELKKNEFQGELEKQREQLDKIQ------SSHNFQLESVNKLYQDEKAVLVNNITTGE 114

Query: 121 ADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI 180
             I  L++QL  L++ + R +  +  ++KN T L ++  Y+  QC  QMKE++ Q EE I
Sbjct: 115 RLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERI 174

Query: 181 KK--------LADQFLEEQKQETQKIQSNDGKE-----LDINNQVVPKNIPKVAENVADK 227
           ++        +A + L E   + Q++Q+    +       + +  VP+    V  N   +
Sbjct: 175 EEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQ 234

Query: 228 NEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISH 287
              PSS  +   K Q+++         E N++  V++ P   R P     +    Q +  
Sbjct: 235 TPAPSSEVVLDSKRQVEKE--------ETNEIQVVNEEPQRDRLP----QEPGREQVVED 282

Query: 288 LPTGQPLSPNMPPDSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKD 347
            P G                G  G   Q P       +   N + E   +  ++    ++
Sbjct: 283 RPVGG------------RGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQE 330

Query: 348 RVSDFHKLKQSRFFDENESPVDPQHGSKLA---DYNGDDGNVGEYEADKQAELAYNEEED 404
                         +E E+  + ++  KL    DYN D+ N  E E DKQA LA N+   
Sbjct: 331 --------------EEQEAAGEGRNQQKLRGEDDYNMDE-NEAESETDKQAALAGNDRNI 375

Query: 405 GDGGEEDVQDD 415
                ED + D
Sbjct: 376 DVFNVEDQKRD 386


>gi|239755081 PREDICTED: similar to golgi membrane protein 1 [Homo
           sapiens]
          Length = 129

 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 39/111 (35%), Positives = 63/111 (56%), Gaps = 6/111 (5%)

Query: 1   MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR 60
           M+G G  RR+ + P LVL  L+  I+VL FNYW  SSR V LQ  + EL+G+V+R    R
Sbjct: 1   MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAER 60

Query: 61  GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVK 111
           G +E + ++    ++  ++Q+D+ +      SS     E + K  +D+K +
Sbjct: 61  GAVELKKNEFQGELEKQREQLDKIQ------SSHNFQLESVNKLYQDEKAR 105


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 53/212 (25%), Positives = 96/212 (45%), Gaps = 32/212 (15%)

Query: 34   SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVD---THKKQIDQKEADYGR 90
            S+  RH    + +AEL+GQV+  +  + +LEK  SDL L VD   T  +Q+ + +A+  +
Sbjct: 1203 SLKKRHA---DSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEK 1259

Query: 91   LSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKN 150
            L +  + R        D   +L N+++ Q       K +L     EFLR+ ++ +     
Sbjct: 1260 LCTLYEERLHEATAKLDKVTQLANDLAAQ-------KTKLWSESGEFLRRLEEKE----- 1307

Query: 151  NTYLVKRLEYESFQCGQQMKELRAQHEENIKKLAD------------QFLEEQKQETQKI 198
               L+ +L  E     +Q+++LR Q E+  K  +               L EQ +E Q++
Sbjct: 1308 --ALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEV 1365

Query: 199  QSNDGKELDINNQVVPKNIPKVAENVADKNEE 230
            ++   + L   N  + +   K   NV  + E+
Sbjct: 1366 KAELHRTLSKVNAEMVQWRMKYENNVIQRTED 1397



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 36/157 (22%), Positives = 73/157 (46%), Gaps = 8/157 (5%)

Query: 34   SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSS 93
            S+S  ++ L+++V EL+G +++   AR   E+    L   +  +++ ++  E+    L+ 
Sbjct: 1031 SLSKANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAE 1090

Query: 94   RLQARE----GLGKRCEDDK---VKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQD 146
             L+ +E     +  + E++K    +LQ  +      I  LKE+L   R    + E +  D
Sbjct: 1091 ELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKMERERAD 1150

Query: 147  YRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKL 183
              ++   L +RLE        Q+ E+  + E   +KL
Sbjct: 1151 LTQDLADLNERLEEVGGSSLAQL-EITKKQETKFQKL 1186



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 46/220 (20%), Positives = 92/220 (41%), Gaps = 38/220 (17%)

Query: 45   EVAELQGQVQRTEVARGRL----EKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREG 100
            ++ +L+GQ+++   ++  L    +K   D  LL + ++++ + K A+  R  S++ A   
Sbjct: 1323 QIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVK-AELHRTLSKVNAE-- 1379

Query: 101  LGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEF----------------------L 138
                    ++K +NN+  +  D+   K++LA   QE                       L
Sbjct: 1380 ----MVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQL 1435

Query: 139  RQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKI 198
               D L D  K  +    RL+ +  Q G+ + + + +HEE+   L     E Q   T+ +
Sbjct: 1436 ELGDALSDLGKVRS-AAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELL 1494

Query: 199  QSNDGKELDINNQVV----PKNIPKVAENVADKNEEPSSN 234
            +  +  E  I  Q       KN+ +   N+ ++  E + N
Sbjct: 1495 KLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKN 1534



 Score = 33.1 bits (74), Expect = 0.51
 Identities = 41/192 (21%), Positives = 78/192 (40%), Gaps = 33/192 (17%)

Query: 42   LQEEVAELQGQVQRTEVARGRLE-------KRNSDLLLLVDTHKKQID------------ 82
            L+EE A+LQ  ++++E  R  L+       +  +DL+L +   ++ +             
Sbjct: 864  LKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKS 923

Query: 83   --QKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQ 140
              Q EA    LS R++  E +         KL++       +I  L+  L +  +E    
Sbjct: 924  KIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTT 983

Query: 141  EDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQS 200
            E ++    KN T  V+ L  +  +  +  K ++  H+        Q L++   E +K+ S
Sbjct: 984  EHKV----KNLTEEVEFLNEDISKLNRAAKVVQEAHQ--------QTLDDLHMEEEKLSS 1031

Query: 201  NDGKELDINNQV 212
                 L +  QV
Sbjct: 1032 LSKANLKLEQQV 1043



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 29/123 (23%), Positives = 56/123 (45%), Gaps = 17/123 (13%)

Query: 78   KKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEF 137
            ++Q+D+ E   G L    +AR      CE +  KL+ N+      + +L+     L +E 
Sbjct: 1040 EQQVDELE---GALEQERKAR----MNCERELHKLEGNLKLNRESMENLESSQRHLAEEL 1092

Query: 138  LRQE---DQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQE 194
             ++E    Q+    +N   LV +L+       + +KEL+ Q ++  +KL  +     K E
Sbjct: 1093 RKKELELSQMNSKVENEKGLVAQLQ-------KTVKELQTQIKDLKEKLEAERTTRAKME 1145

Query: 195  TQK 197
             ++
Sbjct: 1146 RER 1148


>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
          Length = 2003

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 47/199 (23%), Positives = 91/199 (45%), Gaps = 30/199 (15%)

Query: 45   EVAELQGQVQRTEVARGRLEKR---NSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101
            EV ELQG+V + E  R RL ++    ++L    +  + ++  ++ +   + S L+AR G 
Sbjct: 899  EVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGE 958

Query: 102  GKRC----EDDKVKLQNNISYQMADIH--------------HLKEQLAELRQEFLRQEDQ 143
             + C    + +K +LQ +I    A +                 + ++ +  ++ L  EDQ
Sbjct: 959  EEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQ 1018

Query: 144  LQDYRKNNTYLVKRLEYESFQCGQQ------MKELRAQHEENIKKLADQFLEEQK--QET 195
                 K    L  RL   S Q  ++      + +LR ++E  I  + D+  +E+K  QE 
Sbjct: 1019 NSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQEL 1078

Query: 196  QKIQSN-DGKELDINNQVV 213
            +K++   DG+  ++  Q+V
Sbjct: 1079 EKLKRRLDGESSELQEQMV 1097



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 38/185 (20%), Positives = 80/185 (43%), Gaps = 15/185 (8%)

Query: 34   SISSRHVLLQEEVAELQGQVQRTEVARGRLEK-------RNSDLLLLVDTHKKQIDQKEA 86
            S++   +  +  +A+++ ++++ E  R  LEK        +S+L   +   +++ ++  A
Sbjct: 1049 SLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRA 1108

Query: 87   DYGRLSSRLQAREGLGKRCEDD---KVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQ 143
              GR    LQA      R ED+   + +L  ++    A +   +E L   R    + E Q
Sbjct: 1109 QLGRKEEELQAALA---RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1165

Query: 144  LQDYRKNNTYLVKRLE--YESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSN 201
             +D  +    L   LE   +S    Q+++  R Q    +KK  ++     +   Q+++  
Sbjct: 1166 RRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQR 1225

Query: 202  DGKEL 206
             G+ L
Sbjct: 1226 HGQAL 1230



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 43/225 (19%), Positives = 92/225 (40%), Gaps = 25/225 (11%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQARE-- 99
            L+ EV+EL+ ++   + AR   E+R   L L +   + +    E      + +LQ  +  
Sbjct: 1254 LEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAE 1313

Query: 100  -----GLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYL 154
                 G     E   ++L   +S   A +H  +E L E  +  L    +           
Sbjct: 1314 LENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR----------- 1362

Query: 155  VKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQV-- 212
            V+ +E E+    +Q++E  A  E   ++L  Q  + Q  E ++ Q  +   L+   +   
Sbjct: 1363 VRAMEAEAAGLREQLEEEAAARERAGREL--QTAQAQLSEWRRRQEEEAGALEAGEEARR 1420

Query: 213  -VPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEE 256
               +    + + +A+K E  + + +  G+ ++++  D     +E+
Sbjct: 1421 RAAREAEALTQRLAEKTE--TVDRLERGRRRLQQELDDATMDLEQ 1463



 Score = 33.5 bits (75), Expect = 0.39
 Identities = 50/221 (22%), Positives = 91/221 (41%), Gaps = 30/221 (13%)

Query: 48   ELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQ------AREGL 101
            +LQG+ +  E  R +L K+  D  +  D  +KQ     A   +L   L+      A  G 
Sbjct: 1604 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1663

Query: 102  GKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYE 161
            GK   ++ VK    +  QM ++    E+    R+E   Q  + +   K     V RL+ E
Sbjct: 1664 GK---EEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1720

Query: 162  SFQCGQQMKELRAQHEENIKKLAD------QFLEEQKQ----------ETQKIQSNDGKE 205
                 +  ++ +   +E   ++A+        LEE++Q          E ++ QSN    
Sbjct: 1721 LAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNS--- 1777

Query: 206  LDINNQVVPKNIPKVAENVADKNEEPS-SNHIPHGKEQIKR 245
             ++ N    K + +V     + + E S S     G++Q++R
Sbjct: 1778 -ELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLER 1817



 Score = 32.3 bits (72), Expect = 0.87
 Identities = 39/157 (24%), Positives = 70/157 (44%), Gaps = 12/157 (7%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101
            LQE++ E Q   QR E  R +L ++  +L   +    +  D+  A    L S  +A+  L
Sbjct: 1092 LQEQMVEQQ---QRAEELRAQLGRKEEELQAAL---ARAEDEGGARAQLLKSLREAQAAL 1145

Query: 102  GKRCEDDKVK--LQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNN----TYLV 155
             +  ED + +   +     Q  D+    E L    ++ L   +  Q+ R       T L 
Sbjct: 1146 AEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELK 1205

Query: 156  KRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQK 192
            K LE E+      ++ELR +H + + +LA+Q  + ++
Sbjct: 1206 KTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARR 1242


>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
          Length = 1995

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 47/199 (23%), Positives = 91/199 (45%), Gaps = 30/199 (15%)

Query: 45   EVAELQGQVQRTEVARGRLEKR---NSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101
            EV ELQG+V + E  R RL ++    ++L    +  + ++  ++ +   + S L+AR G 
Sbjct: 891  EVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGE 950

Query: 102  GKRC----EDDKVKLQNNISYQMADIH--------------HLKEQLAELRQEFLRQEDQ 143
             + C    + +K +LQ +I    A +                 + ++ +  ++ L  EDQ
Sbjct: 951  EEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQ 1010

Query: 144  LQDYRKNNTYLVKRLEYESFQCGQQ------MKELRAQHEENIKKLADQFLEEQK--QET 195
                 K    L  RL   S Q  ++      + +LR ++E  I  + D+  +E+K  QE 
Sbjct: 1011 NSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQEL 1070

Query: 196  QKIQSN-DGKELDINNQVV 213
            +K++   DG+  ++  Q+V
Sbjct: 1071 EKLKRRLDGESSELQEQMV 1089



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 38/185 (20%), Positives = 80/185 (43%), Gaps = 15/185 (8%)

Query: 34   SISSRHVLLQEEVAELQGQVQRTEVARGRLEK-------RNSDLLLLVDTHKKQIDQKEA 86
            S++   +  +  +A+++ ++++ E  R  LEK        +S+L   +   +++ ++  A
Sbjct: 1041 SLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRA 1100

Query: 87   DYGRLSSRLQAREGLGKRCEDD---KVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQ 143
              GR    LQA      R ED+   + +L  ++    A +   +E L   R    + E Q
Sbjct: 1101 QLGRKEEELQAALA---RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1157

Query: 144  LQDYRKNNTYLVKRLE--YESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSN 201
             +D  +    L   LE   +S    Q+++  R Q    +KK  ++     +   Q+++  
Sbjct: 1158 RRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQR 1217

Query: 202  DGKEL 206
             G+ L
Sbjct: 1218 HGQAL 1222



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 43/225 (19%), Positives = 92/225 (40%), Gaps = 25/225 (11%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQARE-- 99
            L+ EV+EL+ ++   + AR   E+R   L L +   + +    E      + +LQ  +  
Sbjct: 1246 LEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAE 1305

Query: 100  -----GLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYL 154
                 G     E   ++L   +S   A +H  +E L E  +  L    +           
Sbjct: 1306 LENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR----------- 1354

Query: 155  VKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQV-- 212
            V+ +E E+    +Q++E  A  E   ++L  Q  + Q  E ++ Q  +   L+   +   
Sbjct: 1355 VRAMEAEAAGLREQLEEEAAARERAGREL--QTAQAQLSEWRRRQEEEAGALEAGEEARR 1412

Query: 213  -VPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEE 256
               +    + + +A+K E  + + +  G+ ++++  D     +E+
Sbjct: 1413 RAAREAEALTQRLAEKTE--TVDRLERGRRRLQQELDDATMDLEQ 1455



 Score = 33.5 bits (75), Expect = 0.39
 Identities = 50/221 (22%), Positives = 91/221 (41%), Gaps = 30/221 (13%)

Query: 48   ELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQ------AREGL 101
            +LQG+ +  E  R +L K+  D  +  D  +KQ     A   +L   L+      A  G 
Sbjct: 1596 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1655

Query: 102  GKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYE 161
            GK   ++ VK    +  QM ++    E+    R+E   Q  + +   K     V RL+ E
Sbjct: 1656 GK---EEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1712

Query: 162  SFQCGQQMKELRAQHEENIKKLAD------QFLEEQKQ----------ETQKIQSNDGKE 205
                 +  ++ +   +E   ++A+        LEE++Q          E ++ QSN    
Sbjct: 1713 LAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNS--- 1769

Query: 206  LDINNQVVPKNIPKVAENVADKNEEPS-SNHIPHGKEQIKR 245
             ++ N    K + +V     + + E S S     G++Q++R
Sbjct: 1770 -ELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLER 1809



 Score = 32.3 bits (72), Expect = 0.87
 Identities = 39/157 (24%), Positives = 70/157 (44%), Gaps = 12/157 (7%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101
            LQE++ E Q   QR E  R +L ++  +L   +    +  D+  A    L S  +A+  L
Sbjct: 1084 LQEQMVEQQ---QRAEELRAQLGRKEEELQAAL---ARAEDEGGARAQLLKSLREAQAAL 1137

Query: 102  GKRCEDDKVK--LQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNN----TYLV 155
             +  ED + +   +     Q  D+    E L    ++ L   +  Q+ R       T L 
Sbjct: 1138 AEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELK 1197

Query: 156  KRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQK 192
            K LE E+      ++ELR +H + + +LA+Q  + ++
Sbjct: 1198 KTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARR 1234


>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
          Length = 2036

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 47/199 (23%), Positives = 91/199 (45%), Gaps = 30/199 (15%)

Query: 45   EVAELQGQVQRTEVARGRLEKR---NSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101
            EV ELQG+V + E  R RL ++    ++L    +  + ++  ++ +   + S L+AR G 
Sbjct: 932  EVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGE 991

Query: 102  GKRC----EDDKVKLQNNISYQMADIH--------------HLKEQLAELRQEFLRQEDQ 143
             + C    + +K +LQ +I    A +                 + ++ +  ++ L  EDQ
Sbjct: 992  EEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQ 1051

Query: 144  LQDYRKNNTYLVKRLEYESFQCGQQ------MKELRAQHEENIKKLADQFLEEQK--QET 195
                 K    L  RL   S Q  ++      + +LR ++E  I  + D+  +E+K  QE 
Sbjct: 1052 NSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQEL 1111

Query: 196  QKIQSN-DGKELDINNQVV 213
            +K++   DG+  ++  Q+V
Sbjct: 1112 EKLKRRLDGESSELQEQMV 1130



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 38/185 (20%), Positives = 80/185 (43%), Gaps = 15/185 (8%)

Query: 34   SISSRHVLLQEEVAELQGQVQRTEVARGRLEK-------RNSDLLLLVDTHKKQIDQKEA 86
            S++   +  +  +A+++ ++++ E  R  LEK        +S+L   +   +++ ++  A
Sbjct: 1082 SLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRA 1141

Query: 87   DYGRLSSRLQAREGLGKRCEDD---KVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQ 143
              GR    LQA      R ED+   + +L  ++    A +   +E L   R    + E Q
Sbjct: 1142 QLGRKEEELQAALA---RAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQ 1198

Query: 144  LQDYRKNNTYLVKRLE--YESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSN 201
             +D  +    L   LE   +S    Q+++  R Q    +KK  ++     +   Q+++  
Sbjct: 1199 RRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQR 1258

Query: 202  DGKEL 206
             G+ L
Sbjct: 1259 HGQAL 1263



 Score = 35.8 bits (81), Expect = 0.078
 Identities = 43/225 (19%), Positives = 92/225 (40%), Gaps = 25/225 (11%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQARE-- 99
            L+ EV+EL+ ++   + AR   E+R   L L +   + +    E      + +LQ  +  
Sbjct: 1287 LEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAE 1346

Query: 100  -----GLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYL 154
                 G     E   ++L   +S   A +H  +E L E  +  L    +           
Sbjct: 1347 LENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSR----------- 1395

Query: 155  VKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQV-- 212
            V+ +E E+    +Q++E  A  E   ++L  Q  + Q  E ++ Q  +   L+   +   
Sbjct: 1396 VRAMEAEAAGLREQLEEEAAARERAGREL--QTAQAQLSEWRRRQEEEAGALEAGEEARR 1453

Query: 213  -VPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEE 256
               +    + + +A+K E  + + +  G+ ++++  D     +E+
Sbjct: 1454 RAAREAEALTQRLAEKTE--TVDRLERGRRRLQQELDDATMDLEQ 1496



 Score = 33.5 bits (75), Expect = 0.39
 Identities = 50/221 (22%), Positives = 91/221 (41%), Gaps = 30/221 (13%)

Query: 48   ELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQ------AREGL 101
            +LQG+ +  E  R +L K+  D  +  D  +KQ     A   +L   L+      A  G 
Sbjct: 1637 DLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQ 1696

Query: 102  GKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYE 161
            GK   ++ VK    +  QM ++    E+    R+E   Q  + +   K     V RL+ E
Sbjct: 1697 GK---EEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEE 1753

Query: 162  SFQCGQQMKELRAQHEENIKKLAD------QFLEEQKQ----------ETQKIQSNDGKE 205
                 +  ++ +   +E   ++A+        LEE++Q          E ++ QSN    
Sbjct: 1754 LAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNS--- 1810

Query: 206  LDINNQVVPKNIPKVAENVADKNEEPS-SNHIPHGKEQIKR 245
             ++ N    K + +V     + + E S S     G++Q++R
Sbjct: 1811 -ELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLER 1850



 Score = 32.3 bits (72), Expect = 0.87
 Identities = 39/157 (24%), Positives = 70/157 (44%), Gaps = 12/157 (7%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101
            LQE++ E Q   QR E  R +L ++  +L   +    +  D+  A    L S  +A+  L
Sbjct: 1125 LQEQMVEQQ---QRAEELRAQLGRKEEELQAAL---ARAEDEGGARAQLLKSLREAQAAL 1178

Query: 102  GKRCEDDKVK--LQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNN----TYLV 155
             +  ED + +   +     Q  D+    E L    ++ L   +  Q+ R       T L 
Sbjct: 1179 AEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELK 1238

Query: 156  KRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQK 192
            K LE E+      ++ELR +H + + +LA+Q  + ++
Sbjct: 1239 KTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARR 1275


>gi|65301130 kazrin isoform B [Homo sapiens]
          Length = 415

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 46/150 (30%), Positives = 76/150 (50%), Gaps = 16/150 (10%)

Query: 37  SRHVLLQEEVAELQGQV----QRTEVARGRLEK----RNSDLLLLVDTHKKQIDQKEADY 88
           S+ VLL+EEV+ LQ +V    Q  E+    LE+    ++S++L   +  + Q+ QKE + 
Sbjct: 67  SQPVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATEL-RVQLAQKEQEL 125

Query: 89  GRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYR 148
            R    LQA +   KR + +K  L + +    A +   +EQL    ++F+R  +Q   +R
Sbjct: 126 ARAKEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQL----RDFIRNYEQ---HR 178

Query: 149 KNNTYLVKRLEYESFQCGQQMKELRAQHEE 178
           K +   VK L  E     ++  ELR Q +E
Sbjct: 179 KESEDAVKALAKEKDLLEREKWELRRQAKE 208


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 51/220 (23%), Positives = 102/220 (46%), Gaps = 13/220 (5%)

Query: 35  ISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLL---LLVDTHKKQIDQKEADYGRL 91
           I+   + LQ    E++GQV + +  + +LEK   +L+    +++  + ++ +  A Y + 
Sbjct: 294 INELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQA 353

Query: 92  SSRLQAREG-LGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKN 150
           S++  A E  L K  ED   + QN  S + +    +KE+  E ++E  RQ+   Q   + 
Sbjct: 354 STKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQE 413

Query: 151 NTYLVKRLEYESFQCGQQMKELRAQHEE--NIKKLADQFLEEQKQE----TQKIQSNDGK 204
              +  RL  E  Q       L+A+ ++  ++K+  +  LEE KQ+     Q  Q++  K
Sbjct: 414 CIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIK 473

Query: 205 ELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGKEQIK 244
           E ++   +      K   N+   + E  +  + H + ++K
Sbjct: 474 ENELRRSMEEM---KKENNLLKSHSEQKAREVCHLEAELK 510



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 48/207 (23%), Positives = 87/207 (42%), Gaps = 12/207 (5%)

Query: 67  NSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHL 126
           NS    L+D  K Q  +       L  RLQ  E   K   +   +LQ  +     ++   
Sbjct: 273 NSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEK 332

Query: 127 KEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLE--YESFQCGQQMKE-LRAQHEENIKKL 183
           ++ L + R E +R   Q        T L ++L+   E   C +Q  E  R   E+ IK+ 
Sbjct: 333 EKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEK 392

Query: 184 ADQFLEEQKQETQKIQSNDGKELDINNQVV-----PKNIPKVAENVADK---NEEPSSNH 235
             +F EE  ++ +  Q+ D + + +  ++       KN+  V +   DK    ++   N+
Sbjct: 393 EKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENN 452

Query: 236 IPHGKEQIKRGGDAGMPG-IEENDLAK 261
           +   K+++ R   A     I+EN+L +
Sbjct: 453 LEEFKQKLCRAEQAFQASQIKENELRR 479



 Score = 37.0 bits (84), Expect = 0.035
 Identities = 37/172 (21%), Positives = 73/172 (42%), Gaps = 35/172 (20%)

Query: 61   GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCE------------DD 108
            G L+K NSDL        ++++    D+  L  R++  EGL    E            D+
Sbjct: 1833 GELKKENSDL-------SEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIGDN 1885

Query: 109  KVKLQNNISYQMADIHH----LKEQLAELRQEFLRQEDQLQDYR----------KNNTYL 154
              K+ ++   +  D+ +    ++ + A +  E L  E  L+  +          +N   +
Sbjct: 1886 VAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKV 1945

Query: 155  VKRLEYESFQCGQQMKELRAQHEENIKKLA--DQFLEEQKQETQKIQSNDGK 204
            +  LE E      +  +LR + +   KK    DQ  E+ K++TQ+++S+  +
Sbjct: 1946 IVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSE 1997



 Score = 33.1 bits (74), Expect = 0.51
 Identities = 48/234 (20%), Positives = 104/234 (44%), Gaps = 33/234 (14%)

Query: 34   SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSS 93
            ++SS+   L+ E A+L   +   +     L+   + L+  V+  K+++++K+ +  RL +
Sbjct: 2470 NLSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKN 2529

Query: 94   RLQAREGLGKRCEDDKVKLQNNISYQMADIHHL-KEQLAELRQEFLRQEDQLQDYRKNNT 152
            ++Q +E L  +              Q+   H L KEQ  ELR   +  E ++Q  +  N 
Sbjct: 2530 QIQDQEQLVSKLS------------QVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNA 2577

Query: 153  YLVKRLE-----YESFQCGQQMKEL-RAQHEENIKKLA------DQFLEEQKQETQKIQS 200
             L   LE     Y++ +   ++ ++ +    E + K+        + + E  Q+T ++Q 
Sbjct: 2578 SLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQE 2637

Query: 201  N-DGK------ELDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGG 247
               G+      EL +  + +  +  ++ E   + +E   S    H K+Q+++ G
Sbjct: 2638 ELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMH-KDQVEKEG 2690



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 19/109 (17%), Positives = 54/109 (49%), Gaps = 7/109 (6%)

Query: 44  EEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGK 103
           +++ EL+GQ+ + +  + + + +   L   +   K++++ ++ +   L    Q    + +
Sbjct: 18  QKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICE 77

Query: 104 RCEDDKVKL-------QNNISYQMADIHHLKEQLAELRQEFLRQEDQLQ 145
             E  K K+       ++ +++Q   ++  K+Q+ +L QE  R + +L+
Sbjct: 78  SLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELE 126



 Score = 30.4 bits (67), Expect = 3.3
 Identities = 38/181 (20%), Positives = 74/181 (40%), Gaps = 25/181 (13%)

Query: 36   SSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLL---VDTHKKQIDQKEADYGRLS 92
            S R   LQE+ +  Q  V  T  A   LE +  +L LL   V+T + +I + +     L 
Sbjct: 882  SQRISKLQEDTSAHQNVVAETLSA---LENKEKELQLLNDKVETEQAEIQELKKSNHLLE 938

Query: 93   SRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQ--EFLRQEDQLQDYRKN 150
              L+  + L +    +K ++ + IS    +I  L ++   L++    L QE         
Sbjct: 939  DSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQE--------- 989

Query: 151  NTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINN 210
                    +    Q  +       + E++I +L+DQ+ +E+    Q+ +       D++ 
Sbjct: 990  --------KMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQ 1041

Query: 211  Q 211
            +
Sbjct: 1042 K 1042


>gi|157837985 kazrin isoform E [Homo sapiens]
          Length = 775

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 45/147 (30%), Positives = 74/147 (50%), Gaps = 16/147 (10%)

Query: 40  VLLQEEVAELQGQV----QRTEVARGRLEK----RNSDLLLLVDTHKKQIDQKEADYGRL 91
           VLL+EEV+ LQ +V    Q  E+    LE+    ++S++L   +  + Q+ QKE +  R 
Sbjct: 76  VLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATEL-RVQLAQKEQELARA 134

Query: 92  SSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNN 151
              LQA +   KR + +K  L + +    A +   +EQL    ++F+R  +Q   +RK +
Sbjct: 135 KEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQL----RDFIRNYEQ---HRKES 187

Query: 152 TYLVKRLEYESFQCGQQMKELRAQHEE 178
              VK L  E     ++  ELR Q +E
Sbjct: 188 EDAVKALAKEKDLLEREKWELRRQAKE 214


>gi|63147424 kazrin isoform A [Homo sapiens]
          Length = 421

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 45/147 (30%), Positives = 74/147 (50%), Gaps = 16/147 (10%)

Query: 40  VLLQEEVAELQGQV----QRTEVARGRLEK----RNSDLLLLVDTHKKQIDQKEADYGRL 91
           VLL+EEV+ LQ +V    Q  E+    LE+    ++S++L   +  + Q+ QKE +  R 
Sbjct: 76  VLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATEL-RVQLAQKEQELARA 134

Query: 92  SSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNN 151
              LQA +   KR + +K  L + +    A +   +EQL    ++F+R  +Q   +RK +
Sbjct: 135 KEALQAMKADRKRLKGEKTDLVSQMQQLYATLESREEQL----RDFIRNYEQ---HRKES 187

Query: 152 TYLVKRLEYESFQCGQQMKELRAQHEE 178
              VK L  E     ++  ELR Q +E
Sbjct: 188 EDAVKALAKEKDLLEREKWELRRQAKE 214


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 52/250 (20%), Positives = 105/250 (42%), Gaps = 57/250 (22%)

Query: 34   SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDL----------LLLVDTHKKQIDQ 83
            +++   + L+++V +L+G +++ +  R  LE+    L          ++ ++  K+Q+D+
Sbjct: 1025 TLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDE 1084

Query: 84   ----KEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLR 139
                KE +   L S+++  + LG       ++LQ  I    A I  L+E++   R    +
Sbjct: 1085 KLKKKEFEISNLQSKIEDEQALG-------IQLQKKIKELQARIEELEEEIEAERASRAK 1137

Query: 140  QEDQLQDYRKNNTYLVKRLEYESFQCGQQMK----------------------------E 171
             E Q  D  +    + +RLE        Q++                             
Sbjct: 1138 AEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAT 1197

Query: 172  LRAQHEENIKKLADQF--LEEQKQETQKIQSNDGKELD---INNQVVPK---NIPKVAEN 223
            LR +H +++ +L +Q   L+  KQ+ +K +S    E+D    N + V K   N+ K+   
Sbjct: 1198 LRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRT 1257

Query: 224  VADKNEEPSS 233
            + D+  E  S
Sbjct: 1258 LEDQLSELKS 1267



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 48/195 (24%), Positives = 89/195 (45%), Gaps = 24/195 (12%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101
            LQ EV +L   V+RT  A   L+K+  +   ++   K++ ++  A+       L+A +  
Sbjct: 1427 LQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAE-------LEASQKE 1479

Query: 102  GKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYE 161
             +    +  K++N     +  +  LK +   L+QE     +Q+ +  K     +  LE  
Sbjct: 1480 ARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR----IHELEKI 1535

Query: 162  SFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVA 221
              Q  Q+  EL+A  EE     A+  LE ++ +  +IQ      L++ NQV  +   K+A
Sbjct: 1536 KKQVEQEKCELQAALEE-----AEASLEHEEGKILRIQ------LEL-NQVKSEVDRKIA 1583

Query: 222  ENVADKNEEPSSNHI 236
            E   ++ ++   NHI
Sbjct: 1584 EK-DEEIDQLKRNHI 1597



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 51/202 (25%), Positives = 83/202 (41%), Gaps = 29/202 (14%)

Query: 44   EEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGK 103
            + VAEL  Q+   +  + +LEK  S++ + +D     ++      G L       E + +
Sbjct: 1204 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNL-------EKMCR 1256

Query: 104  RCEDDKVKLQNNISYQMADIHHLKEQLAELRQ---EFLRQEDQLQDYRKNNTYLVKRLEY 160
              ED   +L++    Q   I+ L  Q   L+    EF RQ D+ +        LV +L  
Sbjct: 1257 TLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKE-------ALVSQLSR 1309

Query: 161  ESFQCGQQMKELRAQHEENIK---KLAD---------QFLEEQKQETQKIQSNDGKELDI 208
                  QQ++EL+ Q EE IK    LA            L EQ +E Q+ ++   + L  
Sbjct: 1310 GKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSK 1369

Query: 209  NNQVVPKNIPKVAENVADKNEE 230
             N  V +   K   +   + EE
Sbjct: 1370 ANTEVAQWRTKYETDAIQRTEE 1391



 Score = 37.0 bits (84), Expect = 0.035
 Identities = 48/263 (18%), Positives = 105/263 (39%), Gaps = 29/263 (11%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQ--------------KEAD 87
            LQ  + EL+ +++    +R + EK+ SDL   ++   +++++              +EA+
Sbjct: 1117 LQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAE 1176

Query: 88   YGRLSSRLQ----AREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQ 143
            + ++   L+      E                +  Q+ ++  +K++L + + E   + D 
Sbjct: 1177 FQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDD 1236

Query: 144  LQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSN-- 201
            L    +  +     LE        Q+ EL+++ EE  + + D   +  + +T+  + +  
Sbjct: 1237 LASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQ 1296

Query: 202  -DGKE-----LDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIE 255
             D KE     L    Q   + I ++   +  + E  + N + H  +  +   D      E
Sbjct: 1297 LDEKEALVSQLSRGKQAFTQQIEELKRQL--EEEIKAKNALAHALQSSRHDCDLLREQYE 1354

Query: 256  ENDLAKVDDLPPALRKPPISVSQ 278
            E   +K  +L  AL K    V+Q
Sbjct: 1355 EEQESKA-ELQRALSKANTEVAQ 1376



 Score = 33.1 bits (74), Expect = 0.51
 Identities = 40/187 (21%), Positives = 75/187 (40%), Gaps = 30/187 (16%)

Query: 35   ISSRHVLLQEEVAELQGQVQRTEVAR-----------GRLEKRNSDLLLLVDTHKK---Q 80
            +  R  LLQ E+ EL+  +++TE +R            R++  ++    L++T KK    
Sbjct: 1680 VERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETD 1739

Query: 81   IDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEF--- 137
            I Q + +   +    +  E   K+   D   +   +  +     HL+     + Q     
Sbjct: 1740 ISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDL 1799

Query: 138  -LRQED-----------QLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLAD 185
             LR ++           Q+Q        L   +E E  +  + +K LR +HE  +K+L  
Sbjct: 1800 QLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR-KHERRVKELTY 1858

Query: 186  QFLEEQK 192
            Q  E++K
Sbjct: 1859 QTEEDRK 1865



 Score = 28.9 bits (63), Expect = 9.6
 Identities = 34/188 (18%), Positives = 83/188 (44%), Gaps = 27/188 (14%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEAD-----------YGR 90
            +++E  ELQ  ++  E +    E +   + L ++  K ++D+K A+           + R
Sbjct: 1539 VEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIR 1598

Query: 91   LSSRLQAREGLGKRCEDDKV----KLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQD 146
            +   +Q+      R  +D +    K++ +++     ++H     AE  + +   +  L+D
Sbjct: 1599 IVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKD 1658

Query: 147  YR-------KNNTYLVKRL---EYESFQCGQQMKELRA--QHEENIKKLADQFLEEQKQE 194
             +       ++   L ++L   E  +     +++ELRA  +  E  +K+A+Q L +  + 
Sbjct: 1659 TQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASER 1718

Query: 195  TQKIQSND 202
             Q + + +
Sbjct: 1719 VQLLHTQN 1726


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 52/250 (20%), Positives = 105/250 (42%), Gaps = 57/250 (22%)

Query: 34   SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDL----------LLLVDTHKKQIDQ 83
            +++   + L+++V +L+G +++ +  R  LE+    L          ++ ++  K+Q+D+
Sbjct: 1025 TLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDE 1084

Query: 84   ----KEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLR 139
                KE +   L S+++  + LG       ++LQ  I    A I  L+E++   R    +
Sbjct: 1085 KLKKKEFEISNLQSKIEDEQALG-------IQLQKKIKELQARIEELEEEIEAERASRAK 1137

Query: 140  QEDQLQDYRKNNTYLVKRLEYESFQCGQQMK----------------------------E 171
             E Q  D  +    + +RLE        Q++                             
Sbjct: 1138 AEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAT 1197

Query: 172  LRAQHEENIKKLADQF--LEEQKQETQKIQSNDGKELD---INNQVVPK---NIPKVAEN 223
            LR +H +++ +L +Q   L+  KQ+ +K +S    E+D    N + V K   N+ K+   
Sbjct: 1198 LRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRT 1257

Query: 224  VADKNEEPSS 233
            + D+  E  S
Sbjct: 1258 LEDQLSELKS 1267



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 48/195 (24%), Positives = 89/195 (45%), Gaps = 24/195 (12%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101
            LQ EV +L   V+RT  A   L+K+  +   ++   K++ ++  A+       L+A +  
Sbjct: 1427 LQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAE-------LEASQKE 1479

Query: 102  GKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYE 161
             +    +  K++N     +  +  LK +   L+QE     +Q+ +  K     +  LE  
Sbjct: 1480 ARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR----IHELEKI 1535

Query: 162  SFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVA 221
              Q  Q+  EL+A  EE     A+  LE ++ +  +IQ      L++ NQV  +   K+A
Sbjct: 1536 KKQVEQEKCELQAALEE-----AEASLEHEEGKILRIQ------LEL-NQVKSEVDRKIA 1583

Query: 222  ENVADKNEEPSSNHI 236
            E   ++ ++   NHI
Sbjct: 1584 EK-DEEIDQLKRNHI 1597



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 51/202 (25%), Positives = 83/202 (41%), Gaps = 29/202 (14%)

Query: 44   EEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGK 103
            + VAEL  Q+   +  + +LEK  S++ + +D     ++      G L       E + +
Sbjct: 1204 DSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNL-------EKMCR 1256

Query: 104  RCEDDKVKLQNNISYQMADIHHLKEQLAELRQ---EFLRQEDQLQDYRKNNTYLVKRLEY 160
              ED   +L++    Q   I+ L  Q   L+    EF RQ D+ +        LV +L  
Sbjct: 1257 TLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKE-------ALVSQLSR 1309

Query: 161  ESFQCGQQMKELRAQHEENIK---KLAD---------QFLEEQKQETQKIQSNDGKELDI 208
                  QQ++EL+ Q EE IK    LA            L EQ +E Q+ ++   + L  
Sbjct: 1310 GKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSK 1369

Query: 209  NNQVVPKNIPKVAENVADKNEE 230
             N  V +   K   +   + EE
Sbjct: 1370 ANTEVAQWRTKYETDAIQRTEE 1391



 Score = 37.0 bits (84), Expect = 0.035
 Identities = 48/263 (18%), Positives = 105/263 (39%), Gaps = 29/263 (11%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQ--------------KEAD 87
            LQ  + EL+ +++    +R + EK+ SDL   ++   +++++              +EA+
Sbjct: 1117 LQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAE 1176

Query: 88   YGRLSSRLQ----AREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQ 143
            + ++   L+      E                +  Q+ ++  +K++L + + E   + D 
Sbjct: 1177 FQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDD 1236

Query: 144  LQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSN-- 201
            L    +  +     LE        Q+ EL+++ EE  + + D   +  + +T+  + +  
Sbjct: 1237 LASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQ 1296

Query: 202  -DGKE-----LDINNQVVPKNIPKVAENVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIE 255
             D KE     L    Q   + I ++   +  + E  + N + H  +  +   D      E
Sbjct: 1297 LDEKEALVSQLSRGKQAFTQQIEELKRQL--EEEIKAKNALAHALQSSRHDCDLLREQYE 1354

Query: 256  ENDLAKVDDLPPALRKPPISVSQ 278
            E   +K  +L  AL K    V+Q
Sbjct: 1355 EEQESKA-ELQRALSKANTEVAQ 1376



 Score = 33.1 bits (74), Expect = 0.51
 Identities = 40/187 (21%), Positives = 75/187 (40%), Gaps = 30/187 (16%)

Query: 35   ISSRHVLLQEEVAELQGQVQRTEVAR-----------GRLEKRNSDLLLLVDTHKK---Q 80
            +  R  LLQ E+ EL+  +++TE +R            R++  ++    L++T KK    
Sbjct: 1680 VERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETD 1739

Query: 81   IDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEF--- 137
            I Q + +   +    +  E   K+   D   +   +  +     HL+     + Q     
Sbjct: 1740 ISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDL 1799

Query: 138  -LRQED-----------QLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLAD 185
             LR ++           Q+Q        L   +E E  +  + +K LR +HE  +K+L  
Sbjct: 1800 QLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLR-KHERRVKELTY 1858

Query: 186  QFLEEQK 192
            Q  E++K
Sbjct: 1859 QTEEDRK 1865



 Score = 28.9 bits (63), Expect = 9.6
 Identities = 34/188 (18%), Positives = 83/188 (44%), Gaps = 27/188 (14%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEAD-----------YGR 90
            +++E  ELQ  ++  E +    E +   + L ++  K ++D+K A+           + R
Sbjct: 1539 VEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIR 1598

Query: 91   LSSRLQAREGLGKRCEDDKV----KLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQD 146
            +   +Q+      R  +D +    K++ +++     ++H     AE  + +   +  L+D
Sbjct: 1599 IVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKD 1658

Query: 147  YR-------KNNTYLVKRL---EYESFQCGQQMKELRA--QHEENIKKLADQFLEEQKQE 194
             +       ++   L ++L   E  +     +++ELRA  +  E  +K+A+Q L +  + 
Sbjct: 1659 TQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASER 1718

Query: 195  TQKIQSND 202
             Q + + +
Sbjct: 1719 VQLLHTQN 1726


>gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]
          Length = 971

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 45/186 (24%), Positives = 84/186 (45%), Gaps = 26/186 (13%)

Query: 42  LQEEVAELQGQVQRT-EVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREG 100
           L+E+  +LQ +++   EV   +L   N ++  L D  +K               L + EG
Sbjct: 403 LEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKS-----------EQGLGSAEG 451

Query: 101 LGKRCEDDKVKLQNNISYQMADIHHLKEQL----AELRQE---------FLRQEDQLQDY 147
           L    +D + +LQN +      +   K+ L     EL QE          +++E++L+  
Sbjct: 452 LIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVD 511

Query: 148 RKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKEL- 206
           +  +   +K  E    +C +  +ELR QHEE+ K    Q L+ + +E    + +  K++ 
Sbjct: 512 KMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVE 571

Query: 207 DINNQV 212
           D+ NQ+
Sbjct: 572 DLLNQI 577



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 27/129 (20%), Positives = 58/129 (44%), Gaps = 8/129 (6%)

Query: 57  EVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNI 116
           E+A  ++E   S     +D  ++Q  +       L   L+ RE      + +   L  NI
Sbjct: 723 ELAAAKMELERS-----IDISRRQSKEHICRITDLQEELRHREHHISELDKEVQHLHENI 777

Query: 117 SYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQH 176
           S    ++    +++  +R E   Q+ +L++  +   YL++  + E  Q   ++K +  + 
Sbjct: 778 SALTKELEFKGKEILRIRSES-NQQIRLEEMEEK--YLMRESKPEDIQMITELKAMLTER 834

Query: 177 EENIKKLAD 185
           ++ IKKL +
Sbjct: 835 DQIIKKLIE 843


>gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]
          Length = 1140

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 45/186 (24%), Positives = 84/186 (45%), Gaps = 26/186 (13%)

Query: 42  LQEEVAELQGQVQRT-EVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREG 100
           L+E+  +LQ +++   EV   +L   N ++  L D  +K               L + EG
Sbjct: 523 LEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKS-----------EQGLGSAEG 571

Query: 101 LGKRCEDDKVKLQNNISYQMADIHHLKEQL----AELRQE---------FLRQEDQLQDY 147
           L    +D + +LQN +      +   K+ L     EL QE          +++E++L+  
Sbjct: 572 LIASLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVD 631

Query: 148 RKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKEL- 206
           +  +   +K  E    +C +  +ELR QHEE+ K    Q L+ + +E    + +  K++ 
Sbjct: 632 KMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVE 691

Query: 207 DINNQV 212
           D+ NQ+
Sbjct: 692 DLLNQI 697



 Score = 29.6 bits (65), Expect = 5.6
 Identities = 29/149 (19%), Positives = 67/149 (44%), Gaps = 14/149 (9%)

Query: 46   VAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRC 105
            + +LQ +++  E     L+K    L   +    K+++ K  +  R+ S  ++ + +    
Sbjct: 869  ITDLQEELRHREHHISELDKEVQHLHENISALTKELEFKGKEILRIRS--ESNQQIRLHE 926

Query: 106  EDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRK---------NNTYLVK 156
            +D   +L+  +    AD  HL+E+   +R +F +  + L++               YL++
Sbjct: 927  QDLNKRLEKELDVMTAD--HLREKNI-MRADFNKTNELLKEINAALQVSLEEMEEKYLMR 983

Query: 157  RLEYESFQCGQQMKELRAQHEENIKKLAD 185
              + E  Q   ++K +  + ++ IKKL +
Sbjct: 984  ESKPEDIQMITELKAMLTERDQIIKKLIE 1012


>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
          Length = 495

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 46/205 (22%), Positives = 96/205 (46%), Gaps = 16/205 (7%)

Query: 41  LLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQARE- 99
           + +E+  E Q ++++    R  +E+   +  L     +++++++       ++  Q RE 
Sbjct: 223 IYEEDQLEKQQKLEKMNAMRRYIEEFQKEQALWRKKKREEMEEENRKIIEFANMQQQREE 282

Query: 100 ---GLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKN-----N 151
                 +  E+ +++LQN ++ ++ ++   +E L ++RQE L QE+Q + Y+        
Sbjct: 283 DRMAKVQENEEKRLQLQNALTQKLEEMLRQREDLEQVRQE-LYQEEQAEIYKSKLKEEAE 341

Query: 152 TYLVKRLEY-ESFQCGQQMKELRAQ----HEENIKK-LADQFLEEQKQETQKIQSNDGKE 205
             L K+ E  + F+    +KEL  Q     EEN +K +  +F E+ + E    Q    K+
Sbjct: 342 KKLRKQKEMKQDFEEQMALKELVLQAAKEEEENFRKTMLAKFAEDDRIELMNAQKQRMKQ 401

Query: 206 LDINNQVVPKNIPKVAENVADKNEE 230
           L+    V      +  + +ADK  E
Sbjct: 402 LEHRRAVEKLIEERRQQFLADKQRE 426


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 46/196 (23%), Positives = 90/196 (45%), Gaps = 20/196 (10%)

Query: 47   AELQGQVQRTEVARGRLEKRNSDLLL-------LVDTHKKQIDQKEADYGRLSSRLQARE 99
            ++ Q +VQ  +     L+  N +LL        L  + + ++ + E++   L  +L    
Sbjct: 2266 SKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLS 2325

Query: 100  GLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLE 159
               ++C++ K  L+  I  Q ADI + K    +L  +   Q  +    R +    +K  +
Sbjct: 2326 NSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDL--QASRELTSRLHEEINMKEQK 2383

Query: 160  YESFQCGQQ------MKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQVV 213
              S   G++      + ELR QH++ IK+L +  L ++++E   ++  + K +D  NQ++
Sbjct: 2384 IISLLSGKEEAIQVAIAELRQQHDKEIKEL-ENLLSQEEEENIVLEEENKKAVDKTNQLM 2442

Query: 214  P--KNIPKVAENVADK 227
               K I K  EN+  K
Sbjct: 2443 ETLKTIKK--ENIQQK 2456



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 50/214 (23%), Positives = 95/214 (44%), Gaps = 27/214 (12%)

Query: 41   LLQEEVAELQGQVQRTEVARGRLEKRNS----DLLLLVDTHKKQIDQKEADYGRLSSRLQ 96
            LL++E  + + ++Q   + R  L +R S    +L  L D  KK+I   E + G +    +
Sbjct: 983  LLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKE 1042

Query: 97   AREGLGK----RCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNT 152
             +E   K    +C++ ++ L+  IS +  ++ H+++ L    +E L  E+Q Q       
Sbjct: 1043 NKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDL----EEKLAAEEQFQ------- 1091

Query: 153  YLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQV 212
             LVK++         Q+  L+A+  EN   +       QK  T    ++DG  + +  + 
Sbjct: 1092 ALVKQMNQTLQDKTNQIDLLQAEISENQAII-------QKLITSNTDASDGDSVALVKET 1144

Query: 213  VPKNIPKVAENVADKNE-EPSSNHIPHGKEQIKR 245
            V  + P    +   K E E     +   KEQ+++
Sbjct: 1145 VVISPPCTGSSEHWKPELEEKILALEKEKEQLQK 1178



 Score = 37.4 bits (85), Expect = 0.027
 Identities = 47/220 (21%), Positives = 100/220 (45%), Gaps = 20/220 (9%)

Query: 26   VVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQK- 84
            V L     S +S      EEV +LQ Q+ +  +    L+  + +     + H + + QK 
Sbjct: 1319 VELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHE----AEVHAESLQQKL 1374

Query: 85   EADYGRLSSRLQAREGLGKRCEDDKV--KLQNNISYQMADIHHLKEQLAELRQEFLRQED 142
            E+   +++     RE   K  E  K+  K + ++SY    +   +  L +++ E + QED
Sbjct: 1375 ESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQED 1434

Query: 143  -------QLQDYRKNNTYLVKRLEYESFQCGQQMKEL--RAQHEENIKKLADQFLEEQKQ 193
                   QL+   K +   +K+L+ E  +  Q+ +E+   ++ ++ I++     L  +K+
Sbjct: 1435 LIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKE 1494

Query: 194  ETQKIQSNDGKELDINNQVV---PKNIPKVAENVADKNEE 230
              ++ +S   +EL +    +    K++  V   V+ +N+E
Sbjct: 1495 ALKENKSLQ-EELSLARGTIERLTKSLADVESQVSAQNKE 1533



 Score = 37.4 bits (85), Expect = 0.027
 Identities = 42/226 (18%), Positives = 102/226 (45%), Gaps = 39/226 (17%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLL--LVDTHKKQIDQKEADYGRLSSRLQARE 99
            LQEE  +L  +++  +V+  +L ++ + L     +  +  Q+  KE +  RLS+   + +
Sbjct: 2593 LQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQ 2652

Query: 100  GLGKRCEDDKV-----------KLQNNISYQMADIHH-----------LKEQLAELRQEF 137
                  E++ V           ++++ +  ++  +HH            +E++AEL ++ 
Sbjct: 2653 KRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDL 2712

Query: 138  LRQEDQLQDYRKNNTYLVKRLE-----YESFQ-----CGQQMKELRAQHEENIKKLADQF 187
            +  E +L    K N  L  +++       S Q       +++ EL+ +++ ++K+LA   
Sbjct: 2713 VEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQ-- 2770

Query: 188  LEEQ---KQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEE 230
            L+EQ    +E   + S     ++   +    ++ K+ + +  K+E+
Sbjct: 2771 LKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQ 2816



 Score = 37.0 bits (84), Expect = 0.035
 Identities = 86/434 (19%), Positives = 166/434 (38%), Gaps = 76/434 (17%)

Query: 34   SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVD--THKKQIDQKEADYGRL 91
            ++  R  LLQEE  +L  ++ R+ +    L      L L ++  T  K+   KE +  + 
Sbjct: 1536 TVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKS 1595

Query: 92   SSRLQAREGLGKRCEDDK---VKLQN--NISYQMADIHHLKE------------------ 128
            S   ++ E   K  E  K   + LQ+  N+S +   I H+ E                  
Sbjct: 1596 SKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEA 1655

Query: 129  -------QLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYE--------------SFQCGQ 167
                   QL E  QE    +++++ + K+    +  LE E              + +C +
Sbjct: 1656 NKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECME 1715

Query: 168  QMKELRAQHEENIKKLADQF--LEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVA 225
             +    A  +E ++++  ++  L ++ Q     + +  +E+      +  N+ K A   A
Sbjct: 1716 TLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEA 1775

Query: 226  DKNEEPSSNHIPHGKEQIKRGGDAGMPG-IEENDLAKV-------DDLPPALRKPPISVS 277
             +  +  +N    G + I        PG  EE D   +       + +P A    P    
Sbjct: 1776 TEKHDNQTNVTEEGTQSI--------PGETEEQDSLSMSTRPTCSESVPSAKSANPAVSK 1827

Query: 278  QHESHQAI-SHLPTGQPLSPNMPP-DSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPR 335
               SH  I ++L     L   +   +     N     + +N  + L   I  S  D E +
Sbjct: 1828 DFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQI--STKDGELK 1885

Query: 336  I------QTDILKQATKDRVSDFHKLKQSRFFDENESPVDPQHGSKLADYNGDDGNVGEY 389
            +      + ++L Q  ++ +S   KLK++   +E +  ++ +  ++LA+ NG  GN  + 
Sbjct: 1886 MLQEEVTKMNLLNQQIQEELSRVTKLKETA--EEEKDDLEERLMNQLAELNGSIGNYCQD 1943

Query: 390  EADKQAELAYNEEE 403
              D Q +    E E
Sbjct: 1944 VTDAQIKNELLESE 1957



 Score = 36.6 bits (83), Expect = 0.046
 Identities = 43/203 (21%), Positives = 89/203 (43%), Gaps = 34/203 (16%)

Query: 43   QEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAR---- 98
            +E + E +   +   +ARG +E+    L  +      Q  +K+   GRL+   + R    
Sbjct: 1493 KEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLI 1552

Query: 99   ----------EGLGKRCE----------DDKVKLQNNI----SYQMADIHHLKEQLAELR 134
                      + L   CE          +DK KL   I    S ++A+    +E+  EL+
Sbjct: 1553 TEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQ 1612

Query: 135  QEF---LRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKL--ADQFLE 189
            +E+   L+  + + +  +   ++V+ +  E  +   +++   A  +E  K+L  A+Q +E
Sbjct: 1613 KEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEME 1672

Query: 190  EQKQETQKI-QSNDGKELDINNQ 211
            E K++ +K  +S   K L++  +
Sbjct: 1673 EMKEKMRKFAKSKQQKILELEEE 1695



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 28/139 (20%), Positives = 61/139 (43%), Gaps = 7/139 (5%)

Query: 69   DLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMAD----IH 124
            +L  L+   ++++ Q + D  R   ++ A E   K  E  + + Q ++     +    + 
Sbjct: 2009 ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVE 2068

Query: 125  HLKEQLAELRQEFLRQEDQLQDYRK---NNTYLVKRLEYESFQCGQQMKELRAQHEENIK 181
            H K+  AEL    +  +D   +  +   +N  L K L+        QMK+     E  ++
Sbjct: 2069 HRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLE 2128

Query: 182  KLADQFLEEQKQETQKIQS 200
            +  ++ L+E+K   +K+ +
Sbjct: 2129 QAEEKHLKEKKNMQEKLDA 2147



 Score = 30.4 bits (67), Expect = 3.3
 Identities = 19/75 (25%), Positives = 38/75 (50%), Gaps = 6/75 (8%)

Query: 71   LLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQL 130
            +L ++  K+Q+ +K      L   L +R+ + K+ ++ +  L+  +  Q  D + L+EQ 
Sbjct: 1166 ILALEKEKEQLQKK------LQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQF 1219

Query: 131  AELRQEFLRQEDQLQ 145
             E  +E     DQL+
Sbjct: 1220 DEQSKENENIGDQLR 1234



 Score = 30.4 bits (67), Expect = 3.3
 Identities = 40/185 (21%), Positives = 73/185 (39%), Gaps = 22/185 (11%)

Query: 44   EEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGK 103
            +EV +LQ  +  T        K  S L    D   + ID+ +    + S  +Q++E   +
Sbjct: 2171 KEVQQLQENLDSTVTQLAAFTKSMSSLQ---DDRDRVIDEAKKWERKFSDAIQSKEEEIR 2227

Query: 104  RCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESF 163
              ED+   L++ +      +  LK  ++ L  +    E + Q   +    +   L+ E+ 
Sbjct: 2228 LKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENK 2287

Query: 164  QCGQQMKELR----------AQHEENIKKLADQFLEEQKQETQKIQSNDG--------KE 205
            +   Q++E R          A+ E  +K L DQ L +     +K +   G        +E
Sbjct: 2288 ELLSQLEETRHLYHSSQNELAKLESELKSLKDQ-LTDLSNSLEKCKEQKGNLEGIIRQQE 2346

Query: 206  LDINN 210
             DI N
Sbjct: 2347 ADIQN 2351


>gi|5454102 transforming, acidic coiled-coil containing protein 3
           [Homo sapiens]
          Length = 838

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 50/205 (24%), Positives = 97/205 (47%), Gaps = 32/205 (15%)

Query: 41  LLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRL----- 95
           LLQ    +L   V+ T+     L  R  +L      H K ++      G++  R      
Sbjct: 636 LLQYSQKDLDAVVKATQEENRELRSRCEEL------HGKNLE-----LGKIMDRFEEVVY 684

Query: 96  QAREGLGKRCEDDKVKLQNNISYQ---MADIHHLKEQLAELRQEFLRQEDQLQDYRKNNT 152
           QA E + K+ E  K ++Q  +  +     D++ +++  ++L + F +Q++ ++ YRKN  
Sbjct: 685 QAMEEVQKQKELSKAEIQKVLKEKDQLTTDLNSMEKSFSDLFKRFEKQKEVIEGYRKNEE 744

Query: 153 YLVKRLE---YESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQ----KIQSNDGKE 205
            L K +E       Q GQ+ + L+A  EE + +LA++ + + + + Q     +Q++  KE
Sbjct: 745 SLKKCVEDYLARITQEGQRYQALKAHAEEKL-QLANEEIAQVRSKAQAEALALQASLRKE 803

Query: 206 LDINNQVVPKNIPKVAENVADKNEE 230
                Q+  +++ K  E    +NEE
Sbjct: 804 -----QMRIQSLEKTVEQKTKENEE 823


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 54/247 (21%), Positives = 104/247 (42%), Gaps = 57/247 (23%)

Query: 34   SISSRHVLLQEEVAELQGQVQRTEVARGRLE----KRNSDLLLL------VDTHKKQIDQ 83
            +++   + L+++V +L+G +++ +  R  LE    K   DL L       ++  K+Q+D+
Sbjct: 1023 TLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDE 1082

Query: 84   ----KEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLR 139
                KE +   L S+++  + LG       ++LQ  I    A I  L+E++   R    +
Sbjct: 1083 KLKKKEFEMSGLQSKIEDEQALG-------MQLQKKIKELQARIEELEEEIEAERASRAK 1135

Query: 140  QEDQLQDYRKNNTYLVKRLEYESFQCGQQMK----------------------------E 171
             E Q  D  +    + +RLE        Q++                             
Sbjct: 1136 AEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAAT 1195

Query: 172  LRAQHEENIKKLADQF--LEEQKQETQKIQSNDGKELD---INNQVVPK---NIPKVAEN 223
            LR +H +++ +L +Q   L+  KQ+ +K +S    E+D    N + V K   N+ K+   
Sbjct: 1196 LRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRA 1255

Query: 224  VADKNEE 230
            + D+  E
Sbjct: 1256 LEDQLSE 1262



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 48/195 (24%), Positives = 89/195 (45%), Gaps = 24/195 (12%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101
            LQ EV +L   V+RT  A   L+K+  +   ++   K++ ++  A+       L+A +  
Sbjct: 1425 LQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAE-------LEASQKE 1477

Query: 102  GKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYE 161
             +    +  K++N     +  +  LK +   L+QE     +Q+ +  K     +  LE  
Sbjct: 1478 SRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR----IHELEKI 1533

Query: 162  SFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVA 221
              Q  Q+  EL+A  EE     A+  LE ++ +  +IQ      L++ NQV  +   K+A
Sbjct: 1534 KKQVEQEKSELQAALEE-----AEASLEHEEGKILRIQ------LEL-NQVKSEVDRKIA 1581

Query: 222  ENVADKNEEPSSNHI 236
            E   ++ ++   NHI
Sbjct: 1582 EK-DEEIDQMKRNHI 1595



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 47/182 (25%), Positives = 74/182 (40%), Gaps = 30/182 (16%)

Query: 44   EEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGK 103
            + VAEL  Q+   +  + +LEK  S++       K +ID   ++   +S      E + +
Sbjct: 1202 DSVAELGEQIDNLQRVKQKLEKEKSEM-------KMEIDDLASNMETVSKAKGNLEKMCR 1254

Query: 104  RCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESF 163
              ED   +++     Q   I+ L  Q A L+ E      QL +       LV +L     
Sbjct: 1255 ALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDE----KDTLVSQLSRGKQ 1310

Query: 164  QCGQQMKELRAQHEENIKK-----------------LADQFLEEQ--KQETQKIQSNDGK 204
               QQ++EL+ Q EE IK                  L +Q+ EEQ  K E Q+  S    
Sbjct: 1311 AFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANS 1370

Query: 205  EL 206
            E+
Sbjct: 1371 EV 1372



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 40/172 (23%), Positives = 82/172 (47%), Gaps = 21/172 (12%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101
            LQ  + EL+ +++    +R + EK+ SDL        ++I ++  + G  +S   A+  +
Sbjct: 1115 LQARIEELEEEIEAERASRAKAEKQRSDL----SRELEEISERLEEAGGATS---AQIEM 1167

Query: 102  GKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYE 161
             K+ E +  K++ ++  + A + H +   A LR++      +L +   N   + ++LE E
Sbjct: 1168 NKKREAEFQKMRRDL--EEATLQH-EATAATLRKKHADSVAELGEQIDNLQRVKQKLEKE 1224

Query: 162  SFQCGQQMKELRAQHEE------NIKK----LADQFLE-EQKQETQKIQSND 202
              +   ++ +L +  E       N++K    L DQ  E + K+E Q+   ND
Sbjct: 1225 KSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLIND 1276



 Score = 32.7 bits (73), Expect = 0.66
 Identities = 47/218 (21%), Positives = 88/218 (40%), Gaps = 51/218 (23%)

Query: 35   ISSRHVLLQEEVAELQGQVQRTEVAR-----------GRLEKRNSDLLLLVDTHKK---Q 80
            +  R  LLQ E+ EL+  +++TE +R            R++  ++    L++T KK    
Sbjct: 1678 VERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETD 1737

Query: 81   IDQKEADYGRLSSRLQAREGLGKRCEDDKV-----------------KLQNNISYQMADI 123
            I Q + +   +    +  E   K+   D                   +++ N+   + D+
Sbjct: 1738 ISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDL 1797

Query: 124  HHL------------KEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKE 171
             H             K+Q+ +L       E +++  +K N   VK L        +++KE
Sbjct: 1798 QHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHE----RKVKE 1853

Query: 172  LRAQHEE---NIKKLADQFLEEQ-KQETQKIQSNDGKE 205
            L  Q EE   NI +L D   + Q K ++ K Q+ + +E
Sbjct: 1854 LTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEE 1891



 Score = 28.9 bits (63), Expect = 9.6
 Identities = 34/188 (18%), Positives = 84/188 (44%), Gaps = 27/188 (14%)

Query: 42   LQEEVAELQGQVQRTEVA-----------RGRLEKRNSDLLLLVDTHKKQIDQKEADYGR 90
            +++E +ELQ  ++  E +           +  L +  S++   +    ++IDQ + ++ R
Sbjct: 1537 VEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIR 1596

Query: 91   LSSRLQAREGLGKRCEDD----KVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQD 146
            +   +Q+      R  +D    K K++ +++     ++H     AE  + +   +  L+D
Sbjct: 1597 IVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKD 1656

Query: 147  YR-------KNNTYLVKRL---EYESFQCGQQMKELRA--QHEENIKKLADQFLEEQKQE 194
             +       ++   L ++L   E  +     +++ELRA  +  E  +K+A+Q L +  + 
Sbjct: 1657 TQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASER 1716

Query: 195  TQKIQSND 202
             Q + + +
Sbjct: 1717 VQLLHTQN 1724


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 36/167 (21%), Positives = 74/167 (44%), Gaps = 19/167 (11%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHK-------KQIDQKEADYGRLSSR 94
            L +++AELQ Q+   ++   + E+     L  V+          K+I + E+    L   
Sbjct: 1060 LSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQED 1119

Query: 95   LQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYL 154
            L++      + E  K  L         ++  LK +L +       Q++      +    L
Sbjct: 1120 LESERASRNKAEKQKRDLGE-------ELEALKTELEDTLDSTAAQQELRSKREQEVNIL 1172

Query: 155  VKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSN 201
             K LE E+     Q++E+R +H + +++LA     EQ ++T+++++N
Sbjct: 1173 KKTLEEEAKTHEAQIQEMRQKHSQAVEELA-----EQLEQTKRVKAN 1214



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 40/184 (21%), Positives = 83/184 (45%), Gaps = 24/184 (13%)

Query: 26   VVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKE 85
            ++L      ++    LL++ +AE    +   E       +++  L  L + H+  I   E
Sbjct: 981  IILEDQNCKLAKEKKLLEDRIAEFTTNLTEEE-------EKSKSLAKLKNKHEAMITDLE 1033

Query: 86   ADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQ 145
                R   + Q  E   ++ E D   L + I+        L+ Q+AEL+ +  ++E++LQ
Sbjct: 1034 ERLRREEKQRQELEKTRRKLEGDSTDLSDQIA-------ELQAQIAELKMQLAKKEEELQ 1086

Query: 146  DYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQ--KQETQKIQSNDG 203
                     + R+E E+ Q    +K++R + E  I +L +    E+  + + +K + + G
Sbjct: 1087 -------AALARVEEEAAQKNMALKKIR-ELESQISELQEDLESERASRNKAEKQKRDLG 1138

Query: 204  KELD 207
            +EL+
Sbjct: 1139 EELE 1142



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 39/194 (20%), Positives = 89/194 (45%), Gaps = 27/194 (13%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101
            L+E   +L+ +V+  E     L+     +   +   ++Q++++E+   +L       E  
Sbjct: 913  LEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAK 972

Query: 102  GKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYE 161
             K+ E++++ L+              +Q  +L +E    ED++ ++  N T        E
Sbjct: 973  LKKLEEEQIILE--------------DQNCKLAKEKKLLEDRIAEFTTNLT--------E 1010

Query: 162  SFQCGQQMKELRAQHEENIKKLADQFL--EEQKQETQKIQSN-DGKELDINNQV--VPKN 216
              +  + + +L+ +HE  I  L ++    E+Q+QE +K +   +G   D+++Q+  +   
Sbjct: 1011 EEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ 1070

Query: 217  IPKVAENVADKNEE 230
            I ++   +A K EE
Sbjct: 1071 IAELKMQLAKKEEE 1084



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 32/192 (16%), Positives = 84/192 (43%), Gaps = 5/192 (2%)

Query: 44   EEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGK 103
            +++ +LQ Q++              ++L     ++K++   EA+  +L   L A E   +
Sbjct: 1638 KQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKR 1697

Query: 104  RCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESF 163
            + + ++ +L + I+          E+   L     + E++L++ + N   +  RL+  + 
Sbjct: 1698 QAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANL 1757

Query: 164  QCGQ-----QMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIP 218
            Q  Q      ++   AQ  EN ++  ++  +E K + Q+++     +   +   +   I 
Sbjct: 1758 QIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIA 1817

Query: 219  KVAENVADKNEE 230
            ++ E + ++ +E
Sbjct: 1818 QLEEQLDNETKE 1829



 Score = 34.3 bits (77), Expect = 0.23
 Identities = 34/174 (19%), Positives = 71/174 (40%), Gaps = 5/174 (2%)

Query: 41   LLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREG 100
            LL EE        +  + A     ++ +  L L    ++ ++QK A+  RL+ + +    
Sbjct: 1449 LLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQK-AELERLNKQFRTEME 1507

Query: 101  LGKRCEDDKVK----LQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVK 156
                 +DD  K    L+ +       +  +K QL EL  E    ED       N   +  
Sbjct: 1508 DLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKA 1567

Query: 157  RLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINN 210
            + E +     +Q +E + Q    ++++  +  +E+KQ +  + +    E+D+ +
Sbjct: 1568 QFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKD 1621



 Score = 33.9 bits (76), Expect = 0.30
 Identities = 40/224 (17%), Positives = 94/224 (41%), Gaps = 29/224 (12%)

Query: 34   SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQK--------- 84
            S+S++   +++E    + Q++  E A+  LEK+ + L   V   KK+++           
Sbjct: 1326 SLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEE 1385

Query: 85   -----EADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQ---- 135
                 + D   LS R + +     + E  K +LQ  +   + D+ H ++    L +    
Sbjct: 1386 VKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKK 1445

Query: 136  --EFLRQEDQLQ----DYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLE 189
              + L +E  +     + R       +  E ++    + ++E   Q  E +++L  QF  
Sbjct: 1446 FDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAE-LERLNKQFRT 1504

Query: 190  EQKQETQKIQSNDGK---ELDINNQVVPKNIPKVAENVADKNEE 230
            E  ++    + + GK   EL+ + + + + + ++   + +  +E
Sbjct: 1505 EM-EDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDE 1547



 Score = 30.0 bits (66), Expect = 4.3
 Identities = 25/112 (22%), Positives = 47/112 (41%), Gaps = 14/112 (12%)

Query: 42   LQEEVAELQGQVQRTEVARG-------RLEKRNSDLLLLVD-------THKKQIDQKEAD 87
            L+ ++A+L+ Q+      R        R EK+  D+LL VD        +K Q D+    
Sbjct: 1812 LEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTR 1871

Query: 88   YGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLR 139
              +L  +L+  E   +R    + KLQ  +         +  +++ L+ +  R
Sbjct: 1872 LKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRR 1923



 Score = 28.9 bits (63), Expect = 9.6
 Identities = 50/219 (22%), Positives = 87/219 (39%), Gaps = 34/219 (15%)

Query: 38   RHVLLQEEVAELQGQVQRT----EVARGRLEKRNSDLLLLVDT---------HKKQIDQK 84
            +H    EE+AE   Q +R     E A+  LE    +L   V           HK++  + 
Sbjct: 1193 KHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRK--KV 1250

Query: 85   EADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQL 144
            EA    L  +    E +     D   KLQ  +      +     + ++L ++F   E QL
Sbjct: 1251 EAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQL 1310

Query: 145  QD-----YRKNNTYL-----VKRLEYESFQCGQQM-KELRAQH--EENIKKLADQFLEEQ 191
            QD       +N   L     +K++E E     +Q+ +E  A+H  E+ I  L  Q  + +
Sbjct: 1311 QDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMK 1370

Query: 192  KQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNEE 230
            K+    +   +  E       V + + K  E ++ ++EE
Sbjct: 1371 KKMEDSVGCLETAE------EVKRKLQKDLEGLSQRHEE 1403


>gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo
           sapiens]
          Length = 1185

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 50/194 (25%), Positives = 83/194 (42%), Gaps = 22/194 (11%)

Query: 34  SISSRHVLLQEEVAE-LQGQVQRTEVARGRLEKRNSDLLLLVDTH--KKQIDQKEADYGR 90
           S+   H  L E+V E L+  ++R  +    L   + +L++L + +  KK +     D   
Sbjct: 166 SLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGVLDINH 225

Query: 91  LSSRLQAREGLGKRCEDDK----------VKLQNNISYQMADIHHLKEQLAELRQEFLRQ 140
                 +  G  KR  D            ++LQ  IS Q  +   +KE+LA L       
Sbjct: 226 EQENTPSTSG--KRSSDGSLSHEEDLAKVIELQEIISKQSREQSQMKERLASLSSHVTEL 283

Query: 141 EDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQH---EENIKKLADQFLEEQKQETQK 197
           E+ L   RK+   L+K  E  + +  + ++E  AQ    EE I  L  ++L  Q++ T  
Sbjct: 284 EEDLDTARKD---LIKSEEMNT-KLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSV 339

Query: 198 IQSNDGKELDINNQ 211
              ND  E +I N+
Sbjct: 340 HDLNDKLENEIANK 353


>gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo
           sapiens]
          Length = 1202

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 50/194 (25%), Positives = 83/194 (42%), Gaps = 22/194 (11%)

Query: 34  SISSRHVLLQEEVAE-LQGQVQRTEVARGRLEKRNSDLLLLVDTH--KKQIDQKEADYGR 90
           S+   H  L E+V E L+  ++R  +    L   + +L++L + +  KK +     D   
Sbjct: 166 SLFEHHKALDEKVRERLRVALERCSLLEEELGATHKELMILKEQNNQKKTLTDGVLDINH 225

Query: 91  LSSRLQAREGLGKRCEDDK----------VKLQNNISYQMADIHHLKEQLAELRQEFLRQ 140
                 +  G  KR  D            ++LQ  IS Q  +   +KE+LA L       
Sbjct: 226 EQENTPSTSG--KRSSDGSLSHEEDLAKVIELQEIISKQSREQSQMKERLASLSSHVTEL 283

Query: 141 EDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQH---EENIKKLADQFLEEQKQETQK 197
           E+ L   RK+   L+K  E  + +  + ++E  AQ    EE I  L  ++L  Q++ T  
Sbjct: 284 EEDLDTARKD---LIKSEEMNT-KLQRDVREAMAQKEDMEERITTLEKRYLAAQREATSV 339

Query: 198 IQSNDGKELDINNQ 211
              ND  E +I N+
Sbjct: 340 HDLNDKLENEIANK 353


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 48/209 (22%), Positives = 89/209 (42%), Gaps = 44/209 (21%)

Query: 34   SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDL----------LLLVDTHKKQIDQ 83
            S++     L+++V +L+  +++ +  R  LE+    L          +L ++  K+Q+D+
Sbjct: 1020 SLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDE 1079

Query: 84   ----KEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLR 139
                K+ +Y +L S+++  + LG       ++ Q  I    A I  L+E++   R    +
Sbjct: 1080 RLKKKDFEYCQLQSKVEDEQTLG-------LQFQKKIKELQARIEELEEEIEAERATRAK 1132

Query: 140  QEDQLQDYRKNNTYLVKRL-----------------EYESFQCGQQMKELRAQHEENI-- 180
             E Q  DY +    L +RL                 E E  +  + ++E   QHE  +  
Sbjct: 1133 TEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAA 1192

Query: 181  --KKLADQFLE--EQKQETQKIQSNDGKE 205
              KK AD   E  EQ    Q+++    KE
Sbjct: 1193 LRKKHADSVAELGEQIDNLQRVKQKLEKE 1221



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 48/210 (22%), Positives = 87/210 (41%), Gaps = 27/210 (12%)

Query: 44   EEVAELQGQVQRTEVARGRLEKRNSDLLLLVD---THKKQIDQKEADYGRLSSRL--QAR 98
            + VAEL  Q+   +  + +LEK  S+  L +D   +  + + + +A+  ++   L  Q  
Sbjct: 1199 DSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLS 1258

Query: 99   EGLGKRCE---------DDKVKLQ---NNISYQMADIHHLKEQLAELRQEFLRQED---- 142
            E  GK  E           K +LQ     +S Q+ +   +  QL+  +Q F +Q +    
Sbjct: 1259 EARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKR 1318

Query: 143  QLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSND 202
            QL++  K    L   L+     C      LR Q+EE  +  A+      K  ++  Q   
Sbjct: 1319 QLEEENKAKNALAHALQSSRHDCDL----LREQYEEEQEGKAELQRALSKANSEVAQWRT 1374

Query: 203  GKELDI--NNQVVPKNIPKVAENVADKNEE 230
              E D     + + +   K+A+ + D  E+
Sbjct: 1375 KYETDAIQRTEELEEAKKKLAQRLQDSEEQ 1404



 Score = 38.1 bits (87), Expect = 0.016
 Identities = 48/212 (22%), Positives = 100/212 (47%), Gaps = 34/212 (16%)

Query: 35   ISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSR 94
            +  R  LLQ EV EL+  +++TE AR   E+       L+D++    ++ +  + + +S 
Sbjct: 1675 VERRANLLQAEVEELRATLEQTERARKLAEQE------LLDSN----ERVQLLHTQNTSL 1724

Query: 95   LQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQ-------LAELRQEFLRQED---QL 144
            +  +    K+ E D ++LQ+ +     D  + +E+        A + +E  +++D    L
Sbjct: 1725 IHTK----KKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHL 1780

Query: 145  QDYRKNNTYLVKRLEYESFQCGQQM----KELRAQHEENIKKLADQFLEEQKQETQKIQ- 199
            +  +KN    VK L++   +  Q      K+   + E  I++L  +   EQK+ T+ ++ 
Sbjct: 1781 ERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKG 1840

Query: 200  ----SNDGKELDINNQVVPKNIPKVAENVADK 227
                    KEL   ++   KN+ ++ +++ DK
Sbjct: 1841 LRKYERRVKELTYQSEEDRKNVLRL-QDLVDK 1871



 Score = 35.4 bits (80), Expect = 0.10
 Identities = 36/176 (20%), Positives = 70/176 (39%), Gaps = 23/176 (13%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101
            LQ EV +L   V+R       L+K+  +   ++   K + ++ +A+       L+A    
Sbjct: 1422 LQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAE-------LEASLKE 1474

Query: 102  GKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVK----- 156
             +    +  KL+N     +  +  +K +   L QE     +Q+ +  K    L K     
Sbjct: 1475 SRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQI 1534

Query: 157  RLEYESFQCGQQMKELRAQHEE-----------NIKKLADQFLEEQKQETQKIQSN 201
             LE    Q   +  E   +HEE            +K   D+ + E+ +E ++++ N
Sbjct: 1535 ELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRN 1590


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 43/175 (24%), Positives = 84/175 (48%), Gaps = 17/175 (9%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQI-------DQKEADYGRLSSR 94
            L++E+  +  Q  +    R  LE+R SDL   +   +++        ++ E+    L  R
Sbjct: 983  LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042

Query: 95   LQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYL 154
            L+  E   +  E  K KL+ + S     I  L+ Q+AEL+ +  ++E++LQ         
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ-------AA 1095

Query: 155  VKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQ--KQETQKIQSNDGKELD 207
            + RL+ E  Q    +K++R + E +I  L +    E+  + + +K + + G+EL+
Sbjct: 1096 LARLDDEIAQKNNALKKIR-ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1149



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 57/222 (25%), Positives = 96/222 (43%), Gaps = 34/222 (15%)

Query: 38   RHVLLQEEVAELQGQVQRTEVARGR----LEKRNSDL---LLLVDTHKKQIDQKEADYGR 90
            +H    EE+ E   Q +R +    +    LEK N+DL   L ++   K++++ K+     
Sbjct: 1200 KHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA 1259

Query: 91   LSSRLQAREGLGKRCE---DDKV-KLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQD 146
                LQ++   G+R     +DKV KLQN +      ++  + +  +L ++      QLQD
Sbjct: 1260 QVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQD 1319

Query: 147  YRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQE--------TQKI 198
             +       + L+ E+ Q      +LR Q EE    L DQ  EE + +        T  I
Sbjct: 1320 TQ-------ELLQEETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNLERHISTLNI 1371

Query: 199  QSNDGKE--LDINNQVV-----PKNIPKVAENVADKNEEPSS 233
            Q +D K+   D  + V       K   K  EN+  + EE ++
Sbjct: 1372 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAA 1413



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 44/210 (20%), Positives = 96/210 (45%), Gaps = 29/210 (13%)

Query: 34   SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQID----------- 82
            ++S++   L+EE   LQ Q+     A+  LE+  S L + +   KK++            
Sbjct: 1333 NVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1392

Query: 83   -----QKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEF 137
                 QKE +   L+ + + +     + E  K +LQ  +   + D+ + ++ ++ L ++ 
Sbjct: 1393 GKKRFQKEIE--NLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK- 1449

Query: 138  LRQEDQLQDYRKN--NTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLE--EQKQ 193
             R+ DQL    KN  + Y  +R   E+    ++ K L      ++ +  ++ LE  E+ +
Sbjct: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKAL------SLARALEEALEAKEELE 1503

Query: 194  ETQKIQSNDGKELDINNQVVPKNIPKVAEN 223
             T K+   + ++L  +   V KN+ ++ ++
Sbjct: 1504 RTNKMLKAEMEDLVSSKDDVGKNVHELEKS 1533



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 36/175 (20%), Positives = 70/175 (40%), Gaps = 8/175 (4%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101
            L+ ++ +L+ Q       R    K+   L   +   +++++   A    + +  +  E  
Sbjct: 1622 LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK 1681

Query: 102  GKRCEDDKVKLQNNISY-----QMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVK 156
             K  E D ++LQ +++      + AD+   KE+LAE     L   + LQD ++     + 
Sbjct: 1682 AKSLEADLMQLQEDLAAAERARKQADLE--KEELAEELASSLSGRNALQDEKRRLEARIA 1739

Query: 157  RLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQ 211
            +LE E  +  Q   E  +       + A+Q   E   E    Q N+     +  Q
Sbjct: 1740 QLE-EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1793


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 43/175 (24%), Positives = 84/175 (48%), Gaps = 17/175 (9%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQI-------DQKEADYGRLSSR 94
            L++E+  +  Q  +    R  LE+R SDL   +   +++        ++ E+    L  R
Sbjct: 990  LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1049

Query: 95   LQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYL 154
            L+  E   +  E  K KL+ + S     I  L+ Q+AEL+ +  ++E++LQ         
Sbjct: 1050 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ-------AA 1102

Query: 155  VKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQ--KQETQKIQSNDGKELD 207
            + RL+ E  Q    +K++R + E +I  L +    E+  + + +K + + G+EL+
Sbjct: 1103 LARLDDEIAQKNNALKKIR-ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1156



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 57/222 (25%), Positives = 96/222 (43%), Gaps = 34/222 (15%)

Query: 38   RHVLLQEEVAELQGQVQRTEVARGR----LEKRNSDL---LLLVDTHKKQIDQKEADYGR 90
            +H    EE+ E   Q +R +    +    LEK N+DL   L ++   K++++ K+     
Sbjct: 1207 KHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA 1266

Query: 91   LSSRLQAREGLGKRCE---DDKV-KLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQD 146
                LQ++   G+R     +DKV KLQN +      ++  + +  +L ++      QLQD
Sbjct: 1267 QVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQD 1326

Query: 147  YRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQE--------TQKI 198
             +       + L+ E+ Q      +LR Q EE    L DQ  EE + +        T  I
Sbjct: 1327 TQ-------ELLQEETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNLERHISTLNI 1378

Query: 199  QSNDGKE--LDINNQVV-----PKNIPKVAENVADKNEEPSS 233
            Q +D K+   D  + V       K   K  EN+  + EE ++
Sbjct: 1379 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAA 1420



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 44/210 (20%), Positives = 96/210 (45%), Gaps = 29/210 (13%)

Query: 34   SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQID----------- 82
            ++S++   L+EE   LQ Q+     A+  LE+  S L + +   KK++            
Sbjct: 1340 NVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1399

Query: 83   -----QKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEF 137
                 QKE +   L+ + + +     + E  K +LQ  +   + D+ + ++ ++ L ++ 
Sbjct: 1400 GKKRFQKEIE--NLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK- 1456

Query: 138  LRQEDQLQDYRKN--NTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLE--EQKQ 193
             R+ DQL    KN  + Y  +R   E+    ++ K L      ++ +  ++ LE  E+ +
Sbjct: 1457 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKAL------SLARALEEALEAKEELE 1510

Query: 194  ETQKIQSNDGKELDINNQVVPKNIPKVAEN 223
             T K+   + ++L  +   V KN+ ++ ++
Sbjct: 1511 RTNKMLKAEMEDLVSSKDDVGKNVHELEKS 1540



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 36/175 (20%), Positives = 70/175 (40%), Gaps = 8/175 (4%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101
            L+ ++ +L+ Q       R    K+   L   +   +++++   A    + +  +  E  
Sbjct: 1629 LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK 1688

Query: 102  GKRCEDDKVKLQNNISY-----QMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVK 156
             K  E D ++LQ +++      + AD+   KE+LAE     L   + LQD ++     + 
Sbjct: 1689 AKSLEADLMQLQEDLAAAERARKQADLE--KEELAEELASSLSGRNALQDEKRRLEARIA 1746

Query: 157  RLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQ 211
            +LE E  +  Q   E  +       + A+Q   E   E    Q N+     +  Q
Sbjct: 1747 QLE-EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1800


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 43/175 (24%), Positives = 84/175 (48%), Gaps = 17/175 (9%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQI-------DQKEADYGRLSSR 94
            L++E+  +  Q  +    R  LE+R SDL   +   +++        ++ E+    L  R
Sbjct: 990  LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1049

Query: 95   LQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYL 154
            L+  E   +  E  K KL+ + S     I  L+ Q+AEL+ +  ++E++LQ         
Sbjct: 1050 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ-------AA 1102

Query: 155  VKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQ--KQETQKIQSNDGKELD 207
            + RL+ E  Q    +K++R + E +I  L +    E+  + + +K + + G+EL+
Sbjct: 1103 LARLDDEIAQKNNALKKIR-ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1156



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 57/222 (25%), Positives = 96/222 (43%), Gaps = 34/222 (15%)

Query: 38   RHVLLQEEVAELQGQVQRTEVARGR----LEKRNSDL---LLLVDTHKKQIDQKEADYGR 90
            +H    EE+ E   Q +R +    +    LEK N+DL   L ++   K++++ K+     
Sbjct: 1207 KHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA 1266

Query: 91   LSSRLQAREGLGKRCE---DDKV-KLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQD 146
                LQ++   G+R     +DKV KLQN +      ++  + +  +L ++      QLQD
Sbjct: 1267 QVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQD 1326

Query: 147  YRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQE--------TQKI 198
             +       + L+ E+ Q      +LR Q EE    L DQ  EE + +        T  I
Sbjct: 1327 TQ-------ELLQEETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNLERHISTLNI 1378

Query: 199  QSNDGKE--LDINNQVV-----PKNIPKVAENVADKNEEPSS 233
            Q +D K+   D  + V       K   K  EN+  + EE ++
Sbjct: 1379 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAA 1420



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 44/210 (20%), Positives = 96/210 (45%), Gaps = 29/210 (13%)

Query: 34   SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQID----------- 82
            ++S++   L+EE   LQ Q+     A+  LE+  S L + +   KK++            
Sbjct: 1340 NVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1399

Query: 83   -----QKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEF 137
                 QKE +   L+ + + +     + E  K +LQ  +   + D+ + ++ ++ L ++ 
Sbjct: 1400 GKKRFQKEIE--NLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK- 1456

Query: 138  LRQEDQLQDYRKN--NTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLE--EQKQ 193
             R+ DQL    KN  + Y  +R   E+    ++ K L      ++ +  ++ LE  E+ +
Sbjct: 1457 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKAL------SLARALEEALEAKEELE 1510

Query: 194  ETQKIQSNDGKELDINNQVVPKNIPKVAEN 223
             T K+   + ++L  +   V KN+ ++ ++
Sbjct: 1511 RTNKMLKAEMEDLVSSKDDVGKNVHELEKS 1540



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 36/175 (20%), Positives = 70/175 (40%), Gaps = 8/175 (4%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101
            L+ ++ +L+ Q       R    K+   L   +   +++++   A    + +  +  E  
Sbjct: 1629 LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK 1688

Query: 102  GKRCEDDKVKLQNNISY-----QMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVK 156
             K  E D ++LQ +++      + AD+   KE+LAE     L   + LQD ++     + 
Sbjct: 1689 AKSLEADLMQLQEDLAAAERARKQADLE--KEELAEELASSLSGRNALQDEKRRLEARIA 1746

Query: 157  RLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQ 211
            +LE E  +  Q   E  +       + A+Q   E   E    Q N+     +  Q
Sbjct: 1747 QLE-EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1800


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 43/175 (24%), Positives = 84/175 (48%), Gaps = 17/175 (9%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQI-------DQKEADYGRLSSR 94
            L++E+  +  Q  +    R  LE+R SDL   +   +++        ++ E+    L  R
Sbjct: 983  LEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVR 1042

Query: 95   LQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYL 154
            L+  E   +  E  K KL+ + S     I  L+ Q+AEL+ +  ++E++LQ         
Sbjct: 1043 LKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQ-------AA 1095

Query: 155  VKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQ--KQETQKIQSNDGKELD 207
            + RL+ E  Q    +K++R + E +I  L +    E+  + + +K + + G+EL+
Sbjct: 1096 LARLDDEIAQKNNALKKIR-ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELE 1149



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 57/222 (25%), Positives = 96/222 (43%), Gaps = 34/222 (15%)

Query: 38   RHVLLQEEVAELQGQVQRTEVARGR----LEKRNSDL---LLLVDTHKKQIDQKEADYGR 90
            +H    EE+ E   Q +R +    +    LEK N+DL   L ++   K++++ K+     
Sbjct: 1200 KHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA 1259

Query: 91   LSSRLQAREGLGKRCE---DDKV-KLQNNISYQMADIHHLKEQLAELRQEFLRQEDQLQD 146
                LQ++   G+R     +DKV KLQN +      ++  + +  +L ++      QLQD
Sbjct: 1260 QVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQD 1319

Query: 147  YRKNNTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQE--------TQKI 198
             +       + L+ E+ Q      +LR Q EE    L DQ  EE + +        T  I
Sbjct: 1320 TQ-------ELLQEETRQKLNVSTKLR-QLEEERNSLQDQLDEEMEAKQNLERHISTLNI 1371

Query: 199  QSNDGKE--LDINNQVV-----PKNIPKVAENVADKNEEPSS 233
            Q +D K+   D  + V       K   K  EN+  + EE ++
Sbjct: 1372 QLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAA 1413



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 44/210 (20%), Positives = 96/210 (45%), Gaps = 29/210 (13%)

Query: 34   SISSRHVLLQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQID----------- 82
            ++S++   L+EE   LQ Q+     A+  LE+  S L + +   KK++            
Sbjct: 1333 NVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEE 1392

Query: 83   -----QKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQMADIHHLKEQLAELRQEF 137
                 QKE +   L+ + + +     + E  K +LQ  +   + D+ + ++ ++ L ++ 
Sbjct: 1393 GKKRFQKEIE--NLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK- 1449

Query: 138  LRQEDQLQDYRKN--NTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLE--EQKQ 193
             R+ DQL    KN  + Y  +R   E+    ++ K L      ++ +  ++ LE  E+ +
Sbjct: 1450 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKAL------SLARALEEALEAKEELE 1503

Query: 194  ETQKIQSNDGKELDINNQVVPKNIPKVAEN 223
             T K+   + ++L  +   V KN+ ++ ++
Sbjct: 1504 RTNKMLKAEMEDLVSSKDDVGKNVHELEKS 1533



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 36/175 (20%), Positives = 70/175 (40%), Gaps = 8/175 (4%)

Query: 42   LQEEVAELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGL 101
            L+ ++ +L+ Q       R    K+   L   +   +++++   A    + +  +  E  
Sbjct: 1622 LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKK 1681

Query: 102  GKRCEDDKVKLQNNISY-----QMADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVK 156
             K  E D ++LQ +++      + AD+   KE+LAE     L   + LQD ++     + 
Sbjct: 1682 AKSLEADLMQLQEDLAAAERARKQADLE--KEELAEELASSLSGRNALQDEKRRLEARIA 1739

Query: 157  RLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQ 211
            +LE E  +  Q   E  +       + A+Q   E   E    Q N+     +  Q
Sbjct: 1740 QLE-EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQ 1793


>gi|46852174 kinesin family member 3A [Homo sapiens]
          Length = 699

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 52/234 (22%), Positives = 104/234 (44%), Gaps = 28/234 (11%)

Query: 48  ELQGQVQRTEVARGRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCED 107
           +L  + +    AR  LEKR  DLL     H+  +++  A   ++   +   + L K  E 
Sbjct: 436 KLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVI--VGGVDLLAKAEEQ 493

Query: 108 DKVKLQNNISYQ--MADIHHLKEQLAELRQEFLRQEDQ---LQDYRKNNTYLVKRLEYES 162
           +K+  ++N+  +        L+ +L E  QE L  E++   LQ+  +  T  +K++    
Sbjct: 494 EKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTML 553

Query: 163 FQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAE 222
                +M +L+ +H+  I+ L    LE  +Q +++++     ++ I +  +P++  ++ E
Sbjct: 554 MAAKSEMADLQQEHQREIEGL----LENIRQLSRELR----LQMLIIDNFIPRDYQEMIE 605

Query: 223 NVADKNEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISV 276
           N    NE+        G+ Q+K     G      N++ K   +P    K P  V
Sbjct: 606 NYVHWNED-------IGEWQLKCVAYTG------NNMRKQTPVPDKKEKDPFEV 646


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.131    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,015,260
Number of Sequences: 37866
Number of extensions: 946455
Number of successful extensions: 7625
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 160
Number of HSP's successfully gapped in prelim test: 644
Number of HSP's that attempted gapping in prelim test: 5452
Number of HSP's gapped (non-prelim): 2272
length of query: 436
length of database: 18,247,518
effective HSP length: 105
effective length of query: 331
effective length of database: 14,271,588
effective search space: 4723895628
effective search space used: 4723895628
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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