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Search of human proteins with 29789287
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|29789287 inositol 1,4,5-triphosphate receptor interacting
protein [Homo sapiens]
(547 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|29789287 inositol 1,4,5-triphosphate receptor interacting pro... 1120 0.0
gi|57164962 inositol 1,4,5-triphosphate receptor interacting pro... 240 2e-63
gi|57164960 inositol 1,4,5-triphosphate receptor interacting pro... 240 2e-63
gi|77798169 inositol 1,4,5-triphosphate receptor interacting pro... 64 5e-10
gi|115511030 hypothetical protein LOC115004 [Homo sapiens] 47 6e-05
gi|5453730 mab-21-like protein 2 [Homo sapiens] 44 4e-04
gi|5031897 mab-21-like protein 1 [Homo sapiens] 42 0.001
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 38 0.027
gi|166999613 FBJ murine osteosarcoma viral oncogene homolog B is... 35 0.14
gi|4885245 FOS-like antigen 2 [Homo sapiens] 34 0.39
gi|148746195 trichohyalin [Homo sapiens] 34 0.39
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 33 0.51
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 33 0.51
gi|134152708 arginine and glutamate rich 1 [Homo sapiens] 33 0.51
gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens] 33 0.51
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 33 0.67
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 33 0.67
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 33 0.67
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 33 0.67
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 33 0.67
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 33 0.67
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 33 0.67
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 33 0.67
gi|58530842 desmoplakin isoform II [Homo sapiens] 33 0.88
gi|58530840 desmoplakin isoform I [Homo sapiens] 33 0.88
gi|7662088 Rho guanine nucleotide exchange factor (GEF) 12 [Homo... 33 0.88
gi|156766068 CDC42 binding protein kinase gamma (DMPK-like) [Hom... 33 0.88
gi|21735548 centrosomal protein 2 [Homo sapiens] 32 1.1
gi|6681764 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9... 32 1.1
gi|39725636 transmembrane emp24 protein transport domain contain... 32 1.1
>gi|29789287 inositol 1,4,5-triphosphate receptor interacting
protein [Homo sapiens]
Length = 547
Score = 1120 bits (2897), Expect = 0.0
Identities = 547/547 (100%), Positives = 547/547 (100%)
Query: 1 MAMGLFRVCLVVVTAIINHPLLFPRENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVA 60
MAMGLFRVCLVVVTAIINHPLLFPRENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVA
Sbjct: 1 MAMGLFRVCLVVVTAIINHPLLFPRENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVA 60
Query: 61 RLAAEKEALEQVAEEGRQQNETRVAWDLWSTLCMILFLMIEVWRQDHQEGPSPECLGGEE 120
RLAAEKEALEQVAEEGRQQNETRVAWDLWSTLCMILFLMIEVWRQDHQEGPSPECLGGEE
Sbjct: 61 RLAAEKEALEQVAEEGRQQNETRVAWDLWSTLCMILFLMIEVWRQDHQEGPSPECLGGEE 120
Query: 121 DELPGLGGAPLQGLTLPNKATLGHFYERCIRGATADAARTREFLEGFVDDLLEALRSLCN 180
DELPGLGGAPLQGLTLPNKATLGHFYERCIRGATADAARTREFLEGFVDDLLEALRSLCN
Sbjct: 121 DELPGLGGAPLQGLTLPNKATLGHFYERCIRGATADAARTREFLEGFVDDLLEALRSLCN 180
Query: 181 RDTDMEVEDFIGVDSMYENWQVDRPLLCHLFVPFTPPEPYRFHPELWCSGRSVPLDRQGY 240
RDTDMEVEDFIGVDSMYENWQVDRPLLCHLFVPFTPPEPYRFHPELWCSGRSVPLDRQGY
Sbjct: 181 RDTDMEVEDFIGVDSMYENWQVDRPLLCHLFVPFTPPEPYRFHPELWCSGRSVPLDRQGY 240
Query: 241 GQIKVVRADGDTLSCICGKTKLGEDMLCLLHGRNSMAPPCGDMENLLCATDSLYLDTMQV 300
GQIKVVRADGDTLSCICGKTKLGEDMLCLLHGRNSMAPPCGDMENLLCATDSLYLDTMQV
Sbjct: 241 GQIKVVRADGDTLSCICGKTKLGEDMLCLLHGRNSMAPPCGDMENLLCATDSLYLDTMQV 300
Query: 301 MKWFQTALTRAWKGIAHKYEFDLAFGQLDSPGSLKIKFRSGKFMPFNLIPVIQCDDSDLY 360
MKWFQTALTRAWKGIAHKYEFDLAFGQLDSPGSLKIKFRSGKFMPFNLIPVIQCDDSDLY
Sbjct: 301 MKWFQTALTRAWKGIAHKYEFDLAFGQLDSPGSLKIKFRSGKFMPFNLIPVIQCDDSDLY 360
Query: 361 FVSHLPREPSEGTPASSTDWLLSFAVYERHFLRTTLKALPEGACHLSCLQIASFLLSKQS 420
FVSHLPREPSEGTPASSTDWLLSFAVYERHFLRTTLKALPEGACHLSCLQIASFLLSKQS
Sbjct: 361 FVSHLPREPSEGTPASSTDWLLSFAVYERHFLRTTLKALPEGACHLSCLQIASFLLSKQS 420
Query: 421 RLTGPSGLSSYHLKTALLHLLLLRQAADWKAGQLDARLHELLCFLEKSLLQKKLHHFFIG 480
RLTGPSGLSSYHLKTALLHLLLLRQAADWKAGQLDARLHELLCFLEKSLLQKKLHHFFIG
Sbjct: 421 RLTGPSGLSSYHLKTALLHLLLLRQAADWKAGQLDARLHELLCFLEKSLLQKKLHHFFIG 480
Query: 481 NRKVPEAMGLPEAVLRAEPLNLFRPFVLQRSLYRKTLDSFYEMLKNAPALISEYSLHVPS 540
NRKVPEAMGLPEAVLRAEPLNLFRPFVLQRSLYRKTLDSFYEMLKNAPALISEYSLHVPS
Sbjct: 481 NRKVPEAMGLPEAVLRAEPLNLFRPFVLQRSLYRKTLDSFYEMLKNAPALISEYSLHVPS 540
Query: 541 DQPTPKS 547
DQPTPKS
Sbjct: 541 DQPTPKS 547
>gi|57164962 inositol 1,4,5-triphosphate receptor interacting
protein-like 1 isoform 1 [Homo sapiens]
Length = 563
Score = 240 bits (613), Expect = 2e-63
Identities = 167/558 (29%), Positives = 267/558 (47%), Gaps = 48/558 (8%)
Query: 2 AMGLFRVCLVVVTAIINHPLLFP-RENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVA 60
+M + + + V +++HPL+ R + ++ ++M L++E EE
Sbjct: 16 SMAVISLLFLAVMYVVHHPLMVSDRMDLDTLARSRQLEKRMSEEMRLLEMEF----EERK 71
Query: 61 RLAAEKEALEQ--VAEEGRQQ----------------NETRVAW---DLWSTLCMILFLM 99
R A +++ E + Q E + W +LW+T LFL+
Sbjct: 72 RAAEQRQKAENFWTGDTSSDQLVLGKKDMGWPFQADGQEGPLGWMLGNLWNTGLFCLFLV 131
Query: 100 IEVWRQDHQEGPSPECLGGEEDE-LPGLGGAPLQGLT-LPNKATLGHFYERCIRGATADA 157
E+ RQ+ Q P+ + EE+E + + LT P++ L FY+ ++ A D
Sbjct: 132 FELLRQNMQHEPAFDSSSEEEEEEVRVVPVTSYNWLTDFPSQEALDSFYKHYVQNAIRDL 191
Query: 158 ARTREFLEGFVDDLLEALRSLCNRDTDMEVEDFIGVDSMYENW-QVDRPLLCHLFVPFTP 216
T EF+E FVDDL+EA R L ++ ++ED +G+ + +E W + + VP P
Sbjct: 192 PCTCEFVESFVDDLIEACRVLSRQEAHPQLEDCLGIGAAFEKWGTLHETQKFDILVPIVP 251
Query: 217 PEPYRFHPELWCSGRSVPLDRQGYGQIKVVRADGDTLSCICGKTKLGEDMLCLLHGRNSM 276
P+ F E+ R L R+ G + V C+C + KL D+LCL+H
Sbjct: 252 PQGTMFVLEM----RDPALGRR-CGCVLVES------ECVCKREKLLGDVLCLVHHHRDP 300
Query: 277 APPCGDMENLLCAT--DSLYLDTMQVMKWFQTALTRAWKGIAHKYEFDLAFGQLDSPGSL 334
+ G + + A +LD + ++WF+ + AW +AHKY+F L+ + L
Sbjct: 301 SAVLGKCSSSIKAALCTGFHLDVCKTVQWFRNMMGNAWALVAHKYDFKLSLPPSTTSCKL 360
Query: 335 KIKFRSGKFMPFNLIPVIQCDDSDLYFVSHLPREPSEGTPASSTDWLLSFAVYERHFLRT 394
++ +RSG+F+ +L+ +Q +D+ +Y VS P + +S DW SF E FL+
Sbjct: 361 RLDYRSGRFLSIHLVLGVQREDTLVYLVSQAPDQEQ----LTSVDWPESFVACEHLFLKL 416
Query: 395 TLKALPEGACHLSCLQIASFLLSKQSRLTGPSG--LSSYHLKTALLHLLLLRQAADWKAG 452
+ PE CHL CLQI L QS G S L+SYH KTAL+HLLL DW
Sbjct: 417 VGRFAPENTCHLKCLQIILSLRQHQSLPHGASRPILTSYHFKTALMHLLLRLPLTDWAHN 476
Query: 453 QLDARLHELLCFLEKSLLQKKLHHFFIGNRKVPEAMGLPEAVLRAEPLNLFRPFVLQRSL 512
L RL ++L FL + L Q+ LHHF IGN +P + +P+ AEP+NLF+ VL
Sbjct: 477 MLSQRLQDILWFLGRGLQQRSLHHFLIGNNFLPLTIPIPKTFRNAEPVNLFQHLVLNPKA 536
Query: 513 YRKTLDSFYEMLKNAPAL 530
+ + ++ F +L L
Sbjct: 537 HSQAVEEFQNLLTQVKTL 554
>gi|57164960 inositol 1,4,5-triphosphate receptor interacting
protein-like 1 isoform 2 [Homo sapiens]
Length = 555
Score = 240 bits (613), Expect = 2e-63
Identities = 167/558 (29%), Positives = 267/558 (47%), Gaps = 48/558 (8%)
Query: 2 AMGLFRVCLVVVTAIINHPLLFP-RENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVA 60
+M + + + V +++HPL+ R + ++ ++M L++E EE
Sbjct: 8 SMAVISLLFLAVMYVVHHPLMVSDRMDLDTLARSRQLEKRMSEEMRLLEMEF----EERK 63
Query: 61 RLAAEKEALEQ--VAEEGRQQ----------------NETRVAW---DLWSTLCMILFLM 99
R A +++ E + Q E + W +LW+T LFL+
Sbjct: 64 RAAEQRQKAENFWTGDTSSDQLVLGKKDMGWPFQADGQEGPLGWMLGNLWNTGLFCLFLV 123
Query: 100 IEVWRQDHQEGPSPECLGGEEDE-LPGLGGAPLQGLT-LPNKATLGHFYERCIRGATADA 157
E+ RQ+ Q P+ + EE+E + + LT P++ L FY+ ++ A D
Sbjct: 124 FELLRQNMQHEPAFDSSSEEEEEEVRVVPVTSYNWLTDFPSQEALDSFYKHYVQNAIRDL 183
Query: 158 ARTREFLEGFVDDLLEALRSLCNRDTDMEVEDFIGVDSMYENW-QVDRPLLCHLFVPFTP 216
T EF+E FVDDL+EA R L ++ ++ED +G+ + +E W + + VP P
Sbjct: 184 PCTCEFVESFVDDLIEACRVLSRQEAHPQLEDCLGIGAAFEKWGTLHETQKFDILVPIVP 243
Query: 217 PEPYRFHPELWCSGRSVPLDRQGYGQIKVVRADGDTLSCICGKTKLGEDMLCLLHGRNSM 276
P+ F E+ R L R+ G + V C+C + KL D+LCL+H
Sbjct: 244 PQGTMFVLEM----RDPALGRR-CGCVLVES------ECVCKREKLLGDVLCLVHHHRDP 292
Query: 277 APPCGDMENLLCAT--DSLYLDTMQVMKWFQTALTRAWKGIAHKYEFDLAFGQLDSPGSL 334
+ G + + A +LD + ++WF+ + AW +AHKY+F L+ + L
Sbjct: 293 SAVLGKCSSSIKAALCTGFHLDVCKTVQWFRNMMGNAWALVAHKYDFKLSLPPSTTSCKL 352
Query: 335 KIKFRSGKFMPFNLIPVIQCDDSDLYFVSHLPREPSEGTPASSTDWLLSFAVYERHFLRT 394
++ +RSG+F+ +L+ +Q +D+ +Y VS P + +S DW SF E FL+
Sbjct: 353 RLDYRSGRFLSIHLVLGVQREDTLVYLVSQAPDQEQ----LTSVDWPESFVACEHLFLKL 408
Query: 395 TLKALPEGACHLSCLQIASFLLSKQSRLTGPSG--LSSYHLKTALLHLLLLRQAADWKAG 452
+ PE CHL CLQI L QS G S L+SYH KTAL+HLLL DW
Sbjct: 409 VGRFAPENTCHLKCLQIILSLRQHQSLPHGASRPILTSYHFKTALMHLLLRLPLTDWAHN 468
Query: 453 QLDARLHELLCFLEKSLLQKKLHHFFIGNRKVPEAMGLPEAVLRAEPLNLFRPFVLQRSL 512
L RL ++L FL + L Q+ LHHF IGN +P + +P+ AEP+NLF+ VL
Sbjct: 469 MLSQRLQDILWFLGRGLQQRSLHHFLIGNNFLPLTIPIPKTFRNAEPVNLFQHLVLNPKA 528
Query: 513 YRKTLDSFYEMLKNAPAL 530
+ + ++ F +L L
Sbjct: 529 HSQAVEEFQNLLTQVKTL 546
>gi|77798169 inositol 1,4,5-triphosphate receptor interacting
protein-like 2 [Homo sapiens]
Length = 535
Score = 63.5 bits (153), Expect = 5e-10
Identities = 70/241 (29%), Positives = 101/241 (41%), Gaps = 29/241 (12%)
Query: 294 YLDTMQVMKWFQTALTRAWKGIAHKYE----FDLAFGQLDSPGSLKIKFRSGKF------ 343
+L V++WFQ+ L R+ + + E L G L+ P +L I +
Sbjct: 245 HLSATLVLRWFQSHLQRSLATVRYSLEGRCRVTLTPGGLEQPPTLHILPCRTDYGCCRLS 304
Query: 344 MPFNLIPVIQCDDSDLYFVSHLPREPS-------EGTPASSTDWLLSFAVYERHFLRTTL 396
M LIP + D P PS EG A + W ++ A E+ L
Sbjct: 305 MAVRLIPAVHLGDGVFLVAPPPPPLPSAPLLELPEGLRAEAL-WGVNTARQEQKLLSWLQ 363
Query: 397 KALPEGACHLSCLQIASFLLSKQSRLTGPSG-------LSSYHLKTALLHLLLLRQA--A 447
+ GAC+L CLQ+ L +R + LSSY LKT LL +LL + A
Sbjct: 364 ERAAPGACYLKCLQLLKALRDLGARGLDSAAATQWGRILSSYVLKTVLLAVLLRKGAPGQ 423
Query: 448 DWKAGQLDARLHELLCFLEKSLLQK-KLHHFFIGNRKVPEAMG-LPEAVLRAEPLNLFRP 505
W L L EL+ FL LL++ L H +G +G LP+A+ A P++L
Sbjct: 424 GWDEEHLGRCLEELVQFLRDCLLRRHTLFHCVLGPGGAAAEVGPLPKALREAAPVDLLAA 483
Query: 506 F 506
F
Sbjct: 484 F 484
>gi|115511030 hypothetical protein LOC115004 [Homo sapiens]
Length = 522
Score = 46.6 bits (109), Expect = 6e-05
Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 11/126 (8%)
Query: 365 LPREPSEGTPASSTDWLLSFAVYERHFL------RTTLKALPEGACHLSCLQIASFLLSK 418
+P+ EG W LSF+ E+ L +T + E C CL++ +LL +
Sbjct: 360 VPKHAKEGNGFQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKYLLEQ 419
Query: 419 -QSRLTGPSGL---SSYHLKTALLHLLLLR-QAADWKAGQLDARLHELLCFLEKSLLQKK 473
+ R L SSYH+KTA H+ Q + W L + + + L +K
Sbjct: 420 LKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCVTYFLQCLRTEK 479
Query: 474 LHHFFI 479
L ++FI
Sbjct: 480 LENYFI 485
>gi|5453730 mab-21-like protein 2 [Homo sapiens]
Length = 359
Score = 43.9 bits (102), Expect = 4e-04
Identities = 36/131 (27%), Positives = 54/131 (41%), Gaps = 12/131 (9%)
Query: 375 ASSTDWLLSFAVYERHFLRTTLKALPEGACHLSCLQIASFLLSKQSRLTGPSGLSSYHLK 434
A S W+L F E L G C CL + L + L G L++YH+K
Sbjct: 225 AESDAWVLQFGEAENRLLM--------GGCRNKCLSVLKTLRDRHLELPGQP-LNNYHMK 275
Query: 435 TALLHLLLLR-QAADWKAGQLDARLHELLCFLEKSLLQKKLHHFFIGNRKVPEAMGLPEA 493
T LL+ + DW L RL+ +L L L ++ H+F+ N + G P +
Sbjct: 276 TLLLYECEKHPRETDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDL--FQGKPHS 333
Query: 494 VLRAEPLNLFR 504
L + +R
Sbjct: 334 ALESAAKQTWR 344
>gi|5031897 mab-21-like protein 1 [Homo sapiens]
Length = 359
Score = 42.0 bits (97), Expect = 0.001
Identities = 32/108 (29%), Positives = 47/108 (43%), Gaps = 10/108 (9%)
Query: 375 ASSTDWLLSFAVYERHFLRTTLKALPEGACHLSCLQIASFLLSKQSRLTGPSGLSSYHLK 434
A S W+L FA E L G C CL I L + L G L++YH+K
Sbjct: 225 AESDAWVLQFAEAENR--------LQMGGCRKKCLSILKTLRDRHLELPGQP-LNNYHMK 275
Query: 435 TALLHLLLLR-QAADWKAGQLDARLHELLCFLEKSLLQKKLHHFFIGN 481
T + + + +DW L RL+ +L L L ++ H+F+ N
Sbjct: 276 TLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPN 323
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 37.7 bits (86), Expect = 0.027
Identities = 20/59 (33%), Positives = 34/59 (57%)
Query: 25 RENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNETR 83
R A + + +EE R + Q++L+ E+L+ + E RL E+EA +Q E RQ+ E +
Sbjct: 408 RRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKK 466
Score = 29.6 bits (65), Expect = 7.4
Identities = 18/47 (38%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
Query: 35 EEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNE 81
EE+ RK A +E+L+LE+ ++E R E+E +Q EE R+ E
Sbjct: 434 EELKRK--AEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGE 478
>gi|166999613 FBJ murine osteosarcoma viral oncogene homolog B
isoform 1 [Homo sapiens]
Length = 338
Score = 35.4 bits (80), Expect = 0.14
Identities = 23/70 (32%), Positives = 31/70 (44%), Gaps = 21/70 (30%)
Query: 24 PRENATVPENEE---------------------EIIRKMQAHQEKLQLEQLRLEEEVARL 62
PRE PE EE E+ ++QA ++L+ E+ LE E+A L
Sbjct: 145 PREETLTPEEEEKRRVRRERNKLAAAKCRNRRRELTDRLQAETDQLEEEKAELESEIAEL 204
Query: 63 AAEKEALEQV 72
EKE LE V
Sbjct: 205 QKEKERLEFV 214
>gi|4885245 FOS-like antigen 2 [Homo sapiens]
Length = 326
Score = 33.9 bits (76), Expect = 0.39
Identities = 16/35 (45%), Positives = 24/35 (68%)
Query: 36 EIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALE 70
E+ K+QA E+L+ E+ L++E+A L EKE LE
Sbjct: 147 ELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLE 181
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 33.9 bits (76), Expect = 0.39
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 6/65 (9%)
Query: 25 RENATVPENEEEIIRKMQAHQEKLQL------EQLRLEEEVARLAAEKEALEQVAEEGRQ 78
RE +PE EE+ R+ Q + + +L EQL+ E +L E++ L++ E R
Sbjct: 806 REQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRS 865
Query: 79 QNETR 83
Q + R
Sbjct: 866 QEQRR 870
Score = 31.6 bits (70), Expect = 2.0
Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
Query: 25 RENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNETR 83
RE V + EE+++R+ + + +LE+ EEE L E+E L + +E R+Q R
Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELERQYREEE--ELQQEEEQLLREEQEKRRQERER 1197
Score = 31.6 bits (70), Expect = 2.0
Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 11/68 (16%)
Query: 31 PENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAA--------EKEALEQVAEEGR---QQ 79
PE EE+ +R+ + ++ + EQLR E E +L + E+E L Q EE + QQ
Sbjct: 1757 PEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQ 1816
Query: 80 NETRVAWD 87
+ + W+
Sbjct: 1817 RDGKYRWE 1824
Score = 31.6 bits (70), Expect = 2.0
Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 5/69 (7%)
Query: 23 FPRENATVPENEEEIIRKMQAHQE-KLQLEQLRLEEEVARLAAEKE----ALEQVAEEGR 77
F E E EE+ +R Q + + + EQL+LEE+ RL E++ A EQ A + +
Sbjct: 1797 FREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEK 1856
Query: 78 QQNETRVAW 86
+ E + W
Sbjct: 1857 SRREEQELW 1865
Score = 30.0 bits (66), Expect = 5.7
Identities = 19/60 (31%), Positives = 35/60 (58%), Gaps = 3/60 (5%)
Query: 25 RENATVPENEEEIIRKMQAHQEKLQLE-QLRLEEEVARLAAEKEALEQVAEEGRQQNETR 83
RE + + EE+++R+ + + + +LE Q R EEEV + E++ L + E+ R+Q R
Sbjct: 1111 REEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ--EEEQLLREEPEKRRRQELER 1168
Score = 30.0 bits (66), Expect = 5.7
Identities = 19/60 (31%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Query: 23 FPRENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVARL-AAEKEALEQVAEEGRQQNE 81
F E E E+E +R+ + +++ L+ EQLR E E +L E++ + E+ RQ+ E
Sbjct: 1725 FREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQERE 1784
Score = 29.3 bits (64), Expect = 9.7
Identities = 21/59 (35%), Positives = 34/59 (57%), Gaps = 9/59 (15%)
Query: 32 ENEEEIIRKMQAHQ-------EKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNETR 83
+ EEE +RK++ + E+ Q ++LR E+++ R E+E EQ EE R+Q E R
Sbjct: 272 QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRR-KQEEERREQ-QEERREQQERR 328
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 33.5 bits (75), Expect = 0.51
Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Query: 26 ENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNETR 83
EN T+ +N EE+ + E+L+ E LE+E ++L +K+ LE+ + RQQ E +
Sbjct: 792 ENQTLQKNLEEL-KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIK 848
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 33.5 bits (75), Expect = 0.51
Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Query: 26 ENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNETR 83
EN T+ +N EE+ + E+L+ E LE+E ++L +K+ LE+ + RQQ E +
Sbjct: 792 ENQTLQKNLEEL-KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIK 848
>gi|134152708 arginine and glutamate rich 1 [Homo sapiens]
Length = 273
Score = 33.5 bits (75), Expect = 0.51
Identities = 22/47 (46%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 35 EEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNE 81
EE RK+ Q KL EQLR+ EE ++ E+ LEQ E RQQ E
Sbjct: 206 EENNRKIAEAQAKLAEEQLRIVEEQRKIHEERMKLEQ--ERQRQQKE 250
>gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]
Length = 904
Score = 33.5 bits (75), Expect = 0.51
Identities = 19/54 (35%), Positives = 33/54 (61%), Gaps = 2/54 (3%)
Query: 26 ENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQ 79
E + E E++ K +A ++L+ +QL +E E+ RL A+ EAL+ + E R+Q
Sbjct: 787 EKQLLLRQESELMYKSKA--QRLEEQQLDIEGELRRLMAKPEALKSLQERRREQ 838
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 33.1 bits (74), Expect = 0.67
Identities = 24/56 (42%), Positives = 32/56 (57%), Gaps = 8/56 (14%)
Query: 30 VPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNETRVA 85
V + E+E+ + +Q QE+ L+QLR E E AR AAE+ AEE R Q E A
Sbjct: 2058 VQQKEQELQQTLQ--QEQSVLDQLRGEAEAARRAAEE------AEEARVQAEREAA 2105
Score = 32.7 bits (73), Expect = 0.88
Identities = 18/55 (32%), Positives = 32/55 (58%)
Query: 25 RENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQ 79
+E A + + EE + + +A EK+ E+++ +E RL AE E L+Q E ++Q
Sbjct: 2288 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2342
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 33.1 bits (74), Expect = 0.67
Identities = 24/56 (42%), Positives = 32/56 (57%), Gaps = 8/56 (14%)
Query: 30 VPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNETRVA 85
V + E+E+ + +Q QE+ L+QLR E E AR AAE+ AEE R Q E A
Sbjct: 2062 VQQKEQELQQTLQ--QEQSVLDQLRGEAEAARRAAEE------AEEARVQAEREAA 2109
Score = 32.7 bits (73), Expect = 0.88
Identities = 18/55 (32%), Positives = 32/55 (58%)
Query: 25 RENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQ 79
+E A + + EE + + +A EK+ E+++ +E RL AE E L+Q E ++Q
Sbjct: 2292 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2346
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 33.1 bits (74), Expect = 0.67
Identities = 24/56 (42%), Positives = 32/56 (57%), Gaps = 8/56 (14%)
Query: 30 VPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNETRVA 85
V + E+E+ + +Q QE+ L+QLR E E AR AAE+ AEE R Q E A
Sbjct: 2058 VQQKEQELQQTLQ--QEQSVLDQLRGEAEAARRAAEE------AEEARVQAEREAA 2105
Score = 32.7 bits (73), Expect = 0.88
Identities = 18/55 (32%), Positives = 32/55 (58%)
Query: 25 RENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQ 79
+E A + + EE + + +A EK+ E+++ +E RL AE E L+Q E ++Q
Sbjct: 2288 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2342
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 33.1 bits (74), Expect = 0.67
Identities = 24/56 (42%), Positives = 32/56 (57%), Gaps = 8/56 (14%)
Query: 30 VPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNETRVA 85
V + E+E+ + +Q QE+ L+QLR E E AR AAE+ AEE R Q E A
Sbjct: 2026 VQQKEQELQQTLQ--QEQSVLDQLRGEAEAARRAAEE------AEEARVQAEREAA 2073
Score = 32.7 bits (73), Expect = 0.88
Identities = 18/55 (32%), Positives = 32/55 (58%)
Query: 25 RENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQ 79
+E A + + EE + + +A EK+ E+++ +E RL AE E L+Q E ++Q
Sbjct: 2256 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2310
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 33.1 bits (74), Expect = 0.67
Identities = 24/56 (42%), Positives = 32/56 (57%), Gaps = 8/56 (14%)
Query: 30 VPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNETRVA 85
V + E+E+ + +Q QE+ L+QLR E E AR AAE+ AEE R Q E A
Sbjct: 2195 VQQKEQELQQTLQ--QEQSVLDQLRGEAEAARRAAEE------AEEARVQAEREAA 2242
Score = 32.7 bits (73), Expect = 0.88
Identities = 18/55 (32%), Positives = 32/55 (58%)
Query: 25 RENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQ 79
+E A + + EE + + +A EK+ E+++ +E RL AE E L+Q E ++Q
Sbjct: 2425 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2479
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 33.1 bits (74), Expect = 0.67
Identities = 24/56 (42%), Positives = 32/56 (57%), Gaps = 8/56 (14%)
Query: 30 VPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNETRVA 85
V + E+E+ + +Q QE+ L+QLR E E AR AAE+ AEE R Q E A
Sbjct: 2036 VQQKEQELQQTLQ--QEQSVLDQLRGEAEAARRAAEE------AEEARVQAEREAA 2083
Score = 32.7 bits (73), Expect = 0.88
Identities = 18/55 (32%), Positives = 32/55 (58%)
Query: 25 RENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQ 79
+E A + + EE + + +A EK+ E+++ +E RL AE E L+Q E ++Q
Sbjct: 2266 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2320
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 33.1 bits (74), Expect = 0.67
Identities = 24/56 (42%), Positives = 32/56 (57%), Gaps = 8/56 (14%)
Query: 30 VPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNETRVA 85
V + E+E+ + +Q QE+ L+QLR E E AR AAE+ AEE R Q E A
Sbjct: 2044 VQQKEQELQQTLQ--QEQSVLDQLRGEAEAARRAAEE------AEEARVQAEREAA 2091
Score = 32.7 bits (73), Expect = 0.88
Identities = 18/55 (32%), Positives = 32/55 (58%)
Query: 25 RENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQ 79
+E A + + EE + + +A EK+ E+++ +E RL AE E L+Q E ++Q
Sbjct: 2274 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2328
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 33.1 bits (74), Expect = 0.67
Identities = 24/56 (42%), Positives = 32/56 (57%), Gaps = 8/56 (14%)
Query: 30 VPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNETRVA 85
V + E+E+ + +Q QE+ L+QLR E E AR AAE+ AEE R Q E A
Sbjct: 2085 VQQKEQELQQTLQ--QEQSVLDQLRGEAEAARRAAEE------AEEARVQAEREAA 2132
Score = 32.7 bits (73), Expect = 0.88
Identities = 18/55 (32%), Positives = 32/55 (58%)
Query: 25 RENATVPENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQ 79
+E A + + EE + + +A EK+ E+++ +E RL AE E L+Q E ++Q
Sbjct: 2315 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQ 2369
>gi|58530842 desmoplakin isoform II [Homo sapiens]
Length = 2272
Score = 32.7 bits (73), Expect = 0.88
Identities = 15/38 (39%), Positives = 26/38 (68%)
Query: 34 EEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQ 71
+EE IRK+++ +EK + E+ L E+ RL AE + +E+
Sbjct: 1275 KEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEE 1312
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 32.7 bits (73), Expect = 0.88
Identities = 15/38 (39%), Positives = 26/38 (68%)
Query: 34 EEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQ 71
+EE IRK+++ +EK + E+ L E+ RL AE + +E+
Sbjct: 1874 KEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEE 1911
>gi|7662088 Rho guanine nucleotide exchange factor (GEF) 12 [Homo
sapiens]
Length = 1544
Score = 32.7 bits (73), Expect = 0.88
Identities = 23/59 (38%), Positives = 34/59 (57%), Gaps = 6/59 (10%)
Query: 17 INHPLLFPRENATVPENEEEIIRKM-QAHQEKLQLEQLRLEEEVARLAAEKEALEQVAE 74
I P+L EN V + EI+RKM Q QE+LQL L+E+ R A++ L+++ E
Sbjct: 188 ITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQL----LQEDYNRTPAQR-LLKEIQE 241
>gi|156766068 CDC42 binding protein kinase gamma (DMPK-like) [Homo
sapiens]
Length = 1551
Score = 32.7 bits (73), Expect = 0.88
Identities = 18/55 (32%), Positives = 28/55 (50%)
Query: 31 PENEEEIIRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNETRVA 85
P +EE + ++Q +L EQ RLE E+A+ K+ LE E E ++A
Sbjct: 628 PSGKEEALCQLQEENRRLSREQERLEAELAQEQESKQRLEGERRETESNWEAQLA 682
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 32.3 bits (72), Expect = 1.1
Identities = 30/71 (42%), Positives = 38/71 (53%), Gaps = 12/71 (16%)
Query: 30 VPENEEEIIRKM--QAHQEK---LQLEQL-----RLEEEVARLAAEKEAL--EQVAEEGR 77
+ E +EEI +K+ HQ++ QLEQL R EE +AR EKEAL E+ A E R
Sbjct: 685 IQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVR 744
Query: 78 QQNETRVAWDL 88
Q R DL
Sbjct: 745 LQAVERDRQDL 755
Score = 30.4 bits (67), Expect = 4.4
Identities = 18/53 (33%), Positives = 31/53 (58%), Gaps = 2/53 (3%)
Query: 38 IRKMQAHQEKLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNET--RVAWDL 88
++K+ ++ L + + L+ EV L+ E+E L++ EE RQQ E + AW L
Sbjct: 437 LQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRL 489
>gi|6681764 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9,
39kDa [Homo sapiens]
Length = 377
Score = 32.3 bits (72), Expect = 1.1
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 4/113 (3%)
Query: 418 KQSRLTGPSGLSSYHLKT---ALLHLLLLRQAADWKAGQLDARLHELLCFLEKSLLQKKL 474
K GPS +HL A+ H L L A + AR+ E+ F E + + K+
Sbjct: 261 KSFAFVGPSRYLLFHLVKYIFAVAHRLFLPFPLPLFAYRWVARVFEISPF-EPWITRDKV 319
Query: 475 HHFFIGNRKVPEAMGLPEAVLRAEPLNLFRPFVLQRSLYRKTLDSFYEMLKNA 527
I + K+P GL + ++A PL L VL+R + L + E +K A
Sbjct: 320 ERMHITDMKLPHLPGLEDLGIQATPLELKAIEVLRRHRTYRWLSAEIEDVKPA 372
>gi|39725636 transmembrane emp24 protein transport domain containing
9 [Homo sapiens]
Length = 235
Score = 32.3 bits (72), Expect = 1.1
Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 5/64 (7%)
Query: 47 KLQLEQLRLEEEVARLAAEKEALEQVAEEGRQQNET---RVAWDLWSTLCMILFLMIEVW 103
+LQL +L E+V ++ E+ E RQ +E+ RV W WS L ++ + I VW
Sbjct: 163 ELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLW--WSILQTLILVAIGVW 220
Query: 104 RQDH 107
+ H
Sbjct: 221 QMRH 224
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,193,150
Number of Sequences: 37866
Number of extensions: 1108190
Number of successful extensions: 5004
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 62
Number of HSP's that attempted gapping in prelim test: 4482
Number of HSP's gapped (non-prelim): 572
length of query: 547
length of database: 18,247,518
effective HSP length: 107
effective length of query: 440
effective length of database: 14,195,856
effective search space: 6246176640
effective search space used: 6246176640
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.