Guide to the Human Genome
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Search of human proteins with 29550850

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|29550850 golgi membrane protein 1 [Homo sapiens]
         (401 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|29550850 golgi membrane protein 1 [Homo sapiens]                   788   0.0  
gi|29550838 golgi membrane protein 1 [Homo sapiens]                   788   0.0  
gi|239755081 PREDICTED: similar to golgi membrane protein 1 [Hom...   204   1e-52
gi|29826289 cancer susceptibility candidate 4 isoform a [Homo sa...   127   2e-29
gi|29826291 cancer susceptibility candidate 4 isoform b [Homo sa...   121   1e-27
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         57   3e-08
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         57   3e-08
gi|31982906 cingulin-like 1 [Homo sapiens]                             56   5e-08
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    52   1e-06
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    52   1e-06
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]               49   8e-06
gi|221219020 NYD-SP11 protein [Homo sapiens]                           49   1e-05
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...    49   1e-05
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ...    49   1e-05
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...    48   2e-05
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo...    48   2e-05
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo...    48   2e-05
gi|42794779 myosin 18A isoform b [Homo sapiens]                        48   2e-05
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    47   3e-05
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     47   3e-05
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa...    47   3e-05
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]         47   4e-05
gi|28416946 myosin 18A isoform a [Homo sapiens]                        47   4e-05
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             46   5e-05
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...    46   5e-05
gi|148746195 trichohyalin [Homo sapiens]                               45   9e-05
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              45   9e-05
gi|70980531 GGA binding partner [Homo sapiens]                         45   9e-05
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    45   2e-04
gi|13540523 nucleosomal binding protein 1 [Homo sapiens]               44   2e-04

>gi|29550850 golgi membrane protein 1 [Homo sapiens]
          Length = 401

 Score =  788 bits (2034), Expect = 0.0
 Identities = 401/401 (100%), Positives = 401/401 (100%)

Query: 1   MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAER 60
           MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAER
Sbjct: 1   MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAER 60

Query: 61  GAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNITTGERLIRVL 120
           GAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNITTGERLIRVL
Sbjct: 61  GAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNITTGERLIRVL 120

Query: 121 QDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKK 180
           QDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKK
Sbjct: 121 QDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKK 180

Query: 181 GNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSS 240
           GNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSS
Sbjct: 181 GNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSS 240

Query: 241 EVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQTP 300
           EVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQTP
Sbjct: 241 EVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQTP 300

Query: 301 QVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGEGRNQQKLRGEDDYNMDENEAES 360
           QVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGEGRNQQKLRGEDDYNMDENEAES
Sbjct: 301 QVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGEGRNQQKLRGEDDYNMDENEAES 360

Query: 361 ETDKQAALAGNDRNIDVFNVEDQKRDTINLLDQREKRNHTL 401
           ETDKQAALAGNDRNIDVFNVEDQKRDTINLLDQREKRNHTL
Sbjct: 361 ETDKQAALAGNDRNIDVFNVEDQKRDTINLLDQREKRNHTL 401


>gi|29550838 golgi membrane protein 1 [Homo sapiens]
          Length = 401

 Score =  788 bits (2034), Expect = 0.0
 Identities = 401/401 (100%), Positives = 401/401 (100%)

Query: 1   MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAER 60
           MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAER
Sbjct: 1   MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAER 60

Query: 61  GAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNITTGERLIRVL 120
           GAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNITTGERLIRVL
Sbjct: 61  GAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNITTGERLIRVL 120

Query: 121 QDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKK 180
           QDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKK
Sbjct: 121 QDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKK 180

Query: 181 GNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSS 240
           GNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSS
Sbjct: 181 GNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSS 240

Query: 241 EVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQTP 300
           EVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQTP
Sbjct: 241 EVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQTP 300

Query: 301 QVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGEGRNQQKLRGEDDYNMDENEAES 360
           QVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGEGRNQQKLRGEDDYNMDENEAES
Sbjct: 301 QVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGEGRNQQKLRGEDDYNMDENEAES 360

Query: 361 ETDKQAALAGNDRNIDVFNVEDQKRDTINLLDQREKRNHTL 401
           ETDKQAALAGNDRNIDVFNVEDQKRDTINLLDQREKRNHTL
Sbjct: 361 ETDKQAALAGNDRNIDVFNVEDQKRDTINLLDQREKRNHTL 401


>gi|239755081 PREDICTED: similar to golgi membrane protein 1 [Homo
           sapiens]
          Length = 129

 Score =  204 bits (518), Expect = 1e-52
 Identities = 104/104 (100%), Positives = 104/104 (100%)

Query: 1   MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAER 60
           MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAER
Sbjct: 1   MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAER 60

Query: 61  GAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKA 104
           GAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKA
Sbjct: 61  GAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKA 104


>gi|29826289 cancer susceptibility candidate 4 isoform a [Homo
           sapiens]
          Length = 436

 Score =  127 bits (318), Expect = 2e-29
 Identities = 114/431 (26%), Positives = 190/431 (44%), Gaps = 61/431 (14%)

Query: 1   MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAER 60
           M+G G  RR+ + P LVL  L+  I+VL FNYW  SSR V LQ  + EL+G+V+R    R
Sbjct: 1   MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR 60

Query: 61  GAVELKKNEFQGELEKQREQLDKIQ------SSHNFQLESVNKLYQDEKAVLVNNITTGE 114
           G +E + ++    ++  ++Q+D+ +      SS     E + K  +D+K  L NNI+   
Sbjct: 61  GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQM 120

Query: 115 RLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERI 174
             I  L++QL  L++ + R +  +  ++KN T L ++  Y+  QC  QMKE++ Q EE I
Sbjct: 121 ADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI 180

Query: 175 EEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQ 234
           ++        +A + L E   + Q++Q+    +       + +  VP+    V  N   +
Sbjct: 181 KK--------LADQFLEEQKQETQKIQSNDGKE-----LDINNQVVPKNIPKVAENVADK 227

Query: 235 TPAPSSEVVLDSKRQVEKE--------ETNEIQVVNEEPQRDRLP----QEPGREQVVED 282
              PSS  +   K Q+++         E N++  V++ P   R P     +    Q +  
Sbjct: 228 NEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPALRKPPISVSQHESHQAISH 287

Query: 283 RPVGG------------RGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQE 330
            P G                G  G   Q P       +   N + E   +  ++    ++
Sbjct: 288 LPTGQPLSPNMPPDSHINHNGNPGTSKQNPSSPLQRLIPGSNLDSEPRIQTDILKQATKD 347

Query: 331 --------------EEQEAAGEGRNQQKLRGEDDYNMDE-NEAESETDKQAALAGNDRNI 375
                         +E E+  + ++  KL    DYN D+ N  E E DKQA LA N+   
Sbjct: 348 RVSDFHKLKQSRFFDENESPVDPQHGSKLA---DYNGDDGNVGEYEADKQAELAYNEEED 404

Query: 376 DVFNVEDQKRD 386
                ED + D
Sbjct: 405 GDGGEEDVQDD 415


>gi|29826291 cancer susceptibility candidate 4 isoform b [Homo
           sapiens]
          Length = 380

 Score =  121 bits (303), Expect = 1e-27
 Identities = 84/285 (29%), Positives = 143/285 (50%), Gaps = 27/285 (9%)

Query: 1   MMGLGNGRRSMKSPPLVLAALVACIIVLGFNYWIASSRSVDLQTRIMELEGRVRRAAAER 60
           M+G G  RR+ + P LVL  L+  I+VL FNYW  SSR V LQ  + EL+G+V+R    R
Sbjct: 1   MVGFGANRRAGRLPSLVLVVLLVVIVVLAFNYWSISSRHVLLQEEVAELQGQVQRTEVAR 60

Query: 61  GAVELKKNEFQGELEKQREQLDKIQ------SSHNFQLESVNKLYQDEKAVLVNNITTGE 114
           G +E + ++    ++  ++Q+D+ +      SS     E + K  +D+K  L NNI+   
Sbjct: 61  GRLEKRNSDLLLLVDTHKKQIDQKEADYGRLSSRLQAREGLGKRCEDDKVKLQNNISYQM 120

Query: 115 RLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERI 174
             I  L++QL  L++ + R +  +  ++KN T L ++  Y+  QC  QMKE++ Q EE I
Sbjct: 121 ADIHHLKEQLAELRQEFLRQEDQLQDYRKNNTYLVKRLEYESFQCGQQMKELRAQHEENI 180

Query: 175 EEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQ 234
           ++        +A + L E   + Q++Q+    +       + +  VP+    V  N   +
Sbjct: 181 KK--------LADQFLEEQKQETQKIQSNDGKE-----LDINNQVVPKNIPKVAENVADK 227

Query: 235 TPAPSSEVVLDSKRQVEKE--------ETNEIQVVNEEPQRDRLP 271
              PSS  +   K Q+++         E N++  V++ P   R P
Sbjct: 228 NEEPSSNHIPHGKEQIKRGGDAGMPGIEENDLAKVDDLPPALRKP 272


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 56/272 (20%), Positives = 130/272 (47%), Gaps = 19/272 (6%)

Query: 27   VLGFNYWIASSRSVDLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLD---K 83
            +L +N     S+ +++Q  +  ++ R      +  + ++   E + EL + + +L+   K
Sbjct: 3121 LLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLK 3180

Query: 84   IQSSHNFQLESVN---KLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQ---D 137
             Q  H  +LE+     K   DE  +L + + + ++  R LQ  L+  +   GR ++   +
Sbjct: 3181 AQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKE 3240

Query: 138  VLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQR 197
             L+  K     +++ +  L+  + Q K++  + +++IE         +    LSE   + 
Sbjct: 3241 ELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIES-----QRMLYDAQLSEEQGRN 3295

Query: 198  QQLQALSEPQP---RLQAAGLPHT-EVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKE 253
             +LQ L E +    R  ++ L    E+     +  G  +S+ P PS +++ + ++Q+E++
Sbjct: 3296 LELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEK 3355

Query: 254  ETNEIQVVNEEPQRDRLPQEPGREQVVEDRPV 285
             +  ++++N E ++ +L     R+Q+ +DR V
Sbjct: 3356 HSRIVELLN-ETEKYKLDSLQTRQQMEKDRQV 3386



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 55/240 (22%), Positives = 101/240 (42%), Gaps = 32/240 (13%)

Query: 41   DLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQ 100
            DLQ ++  LE  V    +    +E +KN    +L +Q + L+K       QLE + K   
Sbjct: 2018 DLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEK-------QLEKMRKFLD 2070

Query: 101  DEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCI 160
            ++     +     ++ I+ L+ QLK + R           FQ    +  R    ++ Q  
Sbjct: 2071 EQAIDREHERDVFQQEIQKLEQQLKVVPR-----------FQPISEHQTR----EVEQLA 2115

Query: 161  NQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQ-ALSEPQPRLQAAGLPHTE 219
            N +KE  ++C E +       ++    RD+ E N++ ++L+  + E +  L  +     +
Sbjct: 2116 NHLKEKTDKCSELLL------SKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQK 2169

Query: 220  VPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQV 279
            V   K      +K   P  S EV L ++R     +  EI  + E+ ++ R   E   E+V
Sbjct: 2170 VEDRKHFGAVEAK---PELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEV 2226



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 66/352 (18%), Positives = 145/352 (41%), Gaps = 26/352 (7%)

Query: 66  KKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNITTG----ERLIRVLQ 121
           KK +F  ++   +E++   +   + ++E+ NK    EK  ++  + T     E+    L+
Sbjct: 290 KKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELK 349

Query: 122 DQLKTLQRNYGRLQQDVLQFQKNQTNL----------ERKFSYDLSQCINQMKEVKEQ-- 169
           D+L T  +  G LQ+ ++Q  +   N+          ER+ S ++ Q +  ++E++++  
Sbjct: 350 DKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNH 409

Query: 170 CEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLG 229
            + + E    +  E    R L +   +  ++      Q + +       ++ + K    G
Sbjct: 410 KDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKG 469

Query: 230 NSKSQTPAPSSEVVLDSKRQVEKEETNE--IQVVNEEPQRDRLPQEPGREQVVEDRPVGG 287
             ++   + S+  V + + ++     NE  I++ +   Q+++L +E G   ++E++    
Sbjct: 470 EMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELG--LILEEKCALQ 527

Query: 288 RGFGGAGE--LGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGEGRNQQKL 345
           R      E       Q+Q A     E           L   +  + E  +A E R + +L
Sbjct: 528 RQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELEL 587

Query: 346 RGEDDYNMDENEAES-ETDKQAALAGNDRNIDVFNVEDQKRDTINLLDQREK 396
           + E +    + + E  E +K A L   DR  +    E ++  T  L    E+
Sbjct: 588 KHEAEVTNYKIKLEMLEKEKNAVL---DRMAESQEAELERLRTQLLFSHEEE 636



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 37/173 (21%), Positives = 81/173 (46%), Gaps = 22/173 (12%)

Query: 34  IASSRSVDLQTRIMELEGRV---RRAAAERGAVELKKNEFQGE---LEKQREQLDKIQSS 87
           + +S+S ++  +I EL+  +   R+   E+G +E +  E Q +   LEKQ ++ +     
Sbjct: 709 LVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQE 768

Query: 88  HNFQLESVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTN 147
              QLE+ N + +DEK              + L+D LK +     + ++ +        +
Sbjct: 769 KFAQLEAENSILKDEK--------------KTLEDMLK-IHTPVSQEERLIFLDSIKSKS 813

Query: 148 LERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGNE-AVASRDLSENNDQRQQ 199
            +  +  ++   I + +++K+QC +  EE+ K+ N  + A ++   N  + Q+
Sbjct: 814 KDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQE 866



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 5/92 (5%)

Query: 42   LQTRIMELEGRVRRAAA-ERGAVELKKNEFQG-ELEKQREQLDKIQSSHNFQLESVNKLY 99
            LQTR+ ++ G+       E G   L K E +   +  Q   L+ I  +H  +L S+  L 
Sbjct: 1273 LQTRLSKIWGQQTDGMKLEFGEENLPKEETEFLSIHSQMTNLEDIDVNHKSKLSSLQDL- 1331

Query: 100  QDEKAVLVNNITTGERLIRVLQDQLKTLQRNY 131
              EK  L   +   E LI  LQ QLK  ++NY
Sbjct: 1332 --EKTKLEEQVQELESLISSLQQQLKETEQNY 1361



 Score = 33.1 bits (74), Expect = 0.46
 Identities = 30/116 (25%), Positives = 59/116 (50%), Gaps = 18/116 (15%)

Query: 74   LEKQREQLDKIQS----SHNFQLESVNKLYQDEKAVLVNNITTGERLIRVLQDQ--LKTL 127
            L+++RE ++KIQS    S N  ++ ++K   + + VL       E  ++ L++Q   K+ 
Sbjct: 2433 LKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLT------EDALKSLENQTYFKSF 2486

Query: 128  QRNYGRLQQDVLQFQKNQTNLERKFS---YDLSQCINQMKEVKEQCEERIEEVTKK 180
            + N    +  ++  +     LE   S    +L+QC  Q+K+++EQ +   E + KK
Sbjct: 2487 EENG---KGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFETEMLQKK 2539



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 39/182 (21%), Positives = 79/182 (43%), Gaps = 29/182 (15%)

Query: 40   VDLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLY 99
            ++L+TR+++LE  V        A +L       EL +  +Q+  +Q    F+ E + K  
Sbjct: 2495 INLETRLLQLESTV-------SAKDL-------ELTQCYKQIKDMQEQGQFETEMLQKKI 2540

Query: 100  QDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQD--VLQFQKNQTNL-------ER 150
             + + ++   +        V Q QL+ +Q  Y +  QD   +  +  +TN+       E 
Sbjct: 2541 VNLQKIVEEKVAAA----LVSQIQLEAVQ-EYAKFCQDNQTISSEPERTNIQNLNQLRED 2595

Query: 151  KFSYDLSQCINQMKEVKEQ-CEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPR 209
            +   D+S    ++ E++ Q  E     + +K    +A +++ E   +  +LQ L E   +
Sbjct: 2596 ELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEK 2655

Query: 210  LQ 211
             Q
Sbjct: 2656 KQ 2657



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 40/186 (21%), Positives = 82/186 (44%), Gaps = 13/186 (6%)

Query: 34   IASSRSVDLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNF--Q 91
            IA    ++ + +++EL+  +     ++   E K++    E+ K   +L        F  +
Sbjct: 2631 IAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNE 2690

Query: 92   LESVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERK 151
            LE++       KA L +     E+L    Q++L   + N   LQ+D+ Q + +    + K
Sbjct: 2691 LEALRAESVATKAELASYKEKAEKL----QEELLVKETNMTSLQKDLSQVRDHLAEAKEK 2746

Query: 152  FSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASR-----DLSENNDQRQQLQALSEP 206
             S    +   +++E K+ C    E +  K ++++AS+      +S +N   Q L   +  
Sbjct: 2747 LSILEKEDETEVQESKKAC--MFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGI 2804

Query: 207  QPRLQA 212
            Q  LQ+
Sbjct: 2805 QINLQS 2810


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 56/272 (20%), Positives = 130/272 (47%), Gaps = 19/272 (6%)

Query: 27   VLGFNYWIASSRSVDLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLD---K 83
            +L +N     S+ +++Q  +  ++ R      +  + ++   E + EL + + +L+   K
Sbjct: 3113 LLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQTKLELETTLK 3172

Query: 84   IQSSHNFQLESVN---KLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQ---D 137
             Q  H  +LE+     K   DE  +L + + + ++  R LQ  L+  +   GR ++   +
Sbjct: 3173 AQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKAKLGRSEERDKE 3232

Query: 138  VLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQR 197
             L+  K     +++ +  L+  + Q K++  + +++IE         +    LSE   + 
Sbjct: 3233 ELEDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIES-----QRMLYDAQLSEEQGRN 3287

Query: 198  QQLQALSEPQP---RLQAAGLPHT-EVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKE 253
             +LQ L E +    R  ++ L    E+     +  G  +S+ P PS +++ + ++Q+E++
Sbjct: 3288 LELQVLLESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSEDLLKELQKQLEEK 3347

Query: 254  ETNEIQVVNEEPQRDRLPQEPGREQVVEDRPV 285
             +  ++++N E ++ +L     R+Q+ +DR V
Sbjct: 3348 HSRIVELLN-ETEKYKLDSLQTRQQMEKDRQV 3378



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 54/240 (22%), Positives = 98/240 (40%), Gaps = 40/240 (16%)

Query: 41   DLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQ 100
            DLQ ++  LE  V    +    +E +KN    +L +Q + L+K       QLE + K   
Sbjct: 2018 DLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEK-------QLEKMRKFLD 2070

Query: 101  DEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCI 160
            ++     +     ++ I+ L+ QLK + R           FQ    +  R    ++ Q  
Sbjct: 2071 EQAIDREHERDVFQQEIQKLEQQLKVVPR-----------FQPISEHQTR----EVEQLA 2115

Query: 161  NQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQ-ALSEPQPRLQAAGLPHTE 219
            N +KE  ++C E +       ++    RD+ E N++ ++L+  + E +  L      H  
Sbjct: 2116 NHLKEKTDKCSELLL------SKEQLQRDIQERNEEIEKLEFRVRELEQALLVEDRKHFG 2169

Query: 220  VPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQV 279
              + K           P  S EV L ++R     +  EI  + E+ ++ R   E   E+V
Sbjct: 2170 AVEAK-----------PELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEV 2218



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 66/352 (18%), Positives = 145/352 (41%), Gaps = 26/352 (7%)

Query: 66  KKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNITTG----ERLIRVLQ 121
           KK +F  ++   +E++   +   + ++E+ NK    EK  ++  + T     E+    L+
Sbjct: 290 KKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELK 349

Query: 122 DQLKTLQRNYGRLQQDVLQFQKNQTNL----------ERKFSYDLSQCINQMKEVKEQ-- 169
           D+L T  +  G LQ+ ++Q  +   N+          ER+ S ++ Q +  ++E++++  
Sbjct: 350 DKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNH 409

Query: 170 CEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLG 229
            + + E    +  E    R L +   +  ++      Q + +       ++ + K    G
Sbjct: 410 KDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKG 469

Query: 230 NSKSQTPAPSSEVVLDSKRQVEKEETNE--IQVVNEEPQRDRLPQEPGREQVVEDRPVGG 287
             ++   + S+  V + + ++     NE  I++ +   Q+++L +E G   ++E++    
Sbjct: 470 EMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELG--LILEEKCALQ 527

Query: 288 RGFGGAGE--LGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGEGRNQQKL 345
           R      E       Q+Q A     E           L   +  + E  +A E R + +L
Sbjct: 528 RQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELEL 587

Query: 346 RGEDDYNMDENEAES-ETDKQAALAGNDRNIDVFNVEDQKRDTINLLDQREK 396
           + E +    + + E  E +K A L   DR  +    E ++  T  L    E+
Sbjct: 588 KHEAEVTNYKIKLEMLEKEKNAVL---DRMAESQEAELERLRTQLLFSHEEE 636



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 37/173 (21%), Positives = 81/173 (46%), Gaps = 22/173 (12%)

Query: 34  IASSRSVDLQTRIMELEGRV---RRAAAERGAVELKKNEFQGE---LEKQREQLDKIQSS 87
           + +S+S ++  +I EL+  +   R+   E+G +E +  E Q +   LEKQ ++ +     
Sbjct: 709 LVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQE 768

Query: 88  HNFQLESVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTN 147
              QLE+ N + +DEK              + L+D LK +     + ++ +        +
Sbjct: 769 KFAQLEAENSILKDEK--------------KTLEDMLK-IHTPVSQEERLIFLDSIKSKS 813

Query: 148 LERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGNE-AVASRDLSENNDQRQQ 199
            +  +  ++   I + +++K+QC +  EE+ K+ N  + A ++   N  + Q+
Sbjct: 814 KDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQE 866



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 5/92 (5%)

Query: 42   LQTRIMELEGRVRRAAA-ERGAVELKKNEFQG-ELEKQREQLDKIQSSHNFQLESVNKLY 99
            LQTR+ ++ G+       E G   L K E +   +  Q   L+ I  +H  +L S+  L 
Sbjct: 1273 LQTRLSKIWGQQTDGMKLEFGEENLPKEETEFLSIHSQMTNLEDIDVNHKSKLSSLQDL- 1331

Query: 100  QDEKAVLVNNITTGERLIRVLQDQLKTLQRNY 131
              EK  L   +   E LI  LQ QLK  ++NY
Sbjct: 1332 --EKTKLEEQVQELESLISSLQQQLKETEQNY 1361



 Score = 33.1 bits (74), Expect = 0.46
 Identities = 30/116 (25%), Positives = 59/116 (50%), Gaps = 18/116 (15%)

Query: 74   LEKQREQLDKIQS----SHNFQLESVNKLYQDEKAVLVNNITTGERLIRVLQDQ--LKTL 127
            L+++RE ++KIQS    S N  ++ ++K   + + VL       E  ++ L++Q   K+ 
Sbjct: 2425 LKRERESVEKIQSIPENSVNVAIDHLSKDKPELEVVLT------EDALKSLENQTYFKSF 2478

Query: 128  QRNYGRLQQDVLQFQKNQTNLERKFS---YDLSQCINQMKEVKEQCEERIEEVTKK 180
            + N    +  ++  +     LE   S    +L+QC  Q+K+++EQ +   E + KK
Sbjct: 2479 EENG---KGSIINLETRLLQLESTVSAKDLELTQCYKQIKDMQEQGQFETEMLQKK 2531



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 39/182 (21%), Positives = 79/182 (43%), Gaps = 29/182 (15%)

Query: 40   VDLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLY 99
            ++L+TR+++LE  V        A +L       EL +  +Q+  +Q    F+ E + K  
Sbjct: 2487 INLETRLLQLESTV-------SAKDL-------ELTQCYKQIKDMQEQGQFETEMLQKKI 2532

Query: 100  QDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQD--VLQFQKNQTNL-------ER 150
             + + ++   +        V Q QL+ +Q  Y +  QD   +  +  +TN+       E 
Sbjct: 2533 VNLQKIVEEKVAAA----LVSQIQLEAVQ-EYAKFCQDNQTISSEPERTNIQNLNQLRED 2587

Query: 151  KFSYDLSQCINQMKEVKEQ-CEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPR 209
            +   D+S    ++ E++ Q  E     + +K    +A +++ E   +  +LQ L E   +
Sbjct: 2588 ELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEK 2647

Query: 210  LQ 211
             Q
Sbjct: 2648 KQ 2649



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 40/186 (21%), Positives = 82/186 (44%), Gaps = 13/186 (6%)

Query: 34   IASSRSVDLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNF--Q 91
            IA    ++ + +++EL+  +     ++   E K++    E+ K   +L        F  +
Sbjct: 2623 IAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNE 2682

Query: 92   LESVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERK 151
            LE++       KA L +     E+L    Q++L   + N   LQ+D+ Q + +    + K
Sbjct: 2683 LEALRAESVATKAELASYKEKAEKL----QEELLVKETNMTSLQKDLSQVRDHLAEAKEK 2738

Query: 152  FSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASR-----DLSENNDQRQQLQALSEP 206
             S    +   +++E K+ C    E +  K ++++AS+      +S +N   Q L   +  
Sbjct: 2739 LSILEKEDETEVQESKKAC--MFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGI 2796

Query: 207  QPRLQA 212
            Q  LQ+
Sbjct: 2797 QINLQS 2802


>gi|31982906 cingulin-like 1 [Homo sapiens]
          Length = 1302

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 79/320 (24%), Positives = 138/320 (43%), Gaps = 44/320 (13%)

Query: 42  LQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQD 101
           LQ R+ E EG +R+   E   V++++ + Q E+   ++QL ++      +L+S  +    
Sbjct: 668 LQQRLEESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSEMHD----ELDSAKRSEDR 723

Query: 102 EKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQ-TNLERKFSYDLSQCI 160
           EK  L+  +   +   + LQD L   +      Q+D+L+ ++ + T L+     ++S   
Sbjct: 724 EKGALIEELLQAK---QDLQDLLIAKEE-----QEDLLRKRERELTALKGALKEEVSSHD 775

Query: 161 NQMKEVKEQCE-------ERIEEVTKKGNEAVASRDLSENNDQ---RQQLQALSEPQPRL 210
            +M ++KEQ +       E +EE T K  E +ASR  +   DQ     +++ L E   +L
Sbjct: 776 QEMDKLKEQYDAELQALRESVEEAT-KNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKL 834

Query: 211 QAAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVE--KEETNEIQVVNEEPQRD 268
                      QG+   L    +Q      ++  D  +  E  K+   EI+ + E     
Sbjct: 835 -----------QGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHA 883

Query: 269 RLPQEPGREQVVEDRPVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDG 328
           R  +   +E V   R +        G L QT Q Q  LS   E  + E  +++QL     
Sbjct: 884 RKEE---KEAVSARRALENELEAAQGNLSQTTQEQKQLS---EKLKEESEQKEQLRRLK- 936

Query: 329 QEEEQEAAGEGRNQQKLRGE 348
            E E E    G+  +KL+ E
Sbjct: 937 NEMENERWHLGKTIEKLQKE 956



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 5/112 (4%)

Query: 40   VDLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLY 99
            V ++ RI ELE R+     +R  ++L     +    K +E + ++   H    +  ++L 
Sbjct: 1149 VQMEARIAELEDRLESEERDRANLQLSNRRLE---RKVKELVMQVDDEHLSLTDQKDQLS 1205

Query: 100  QDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERK 151
               KA +   +   E  I  L+   K LQR     Q D+ +  + Q N  +K
Sbjct: 1206 LRLKA-MKRQVEEAEEEIDRLESSKKKLQRELEE-QMDMNEHLQGQLNSMKK 1255


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 84/360 (23%), Positives = 146/360 (40%), Gaps = 43/360 (11%)

Query: 41   DLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQ 100
            +LQ RI ELE  +    A R   E +++++  ELE+  E+L++     + Q+E +NK  +
Sbjct: 1111 ELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIE-LNKKRE 1169

Query: 101  DEKAVLVNNITTG----ERLIRVLQ-----------DQLKTLQRNYGRLQQDVLQFQKNQ 145
             E   L  ++       E ++  L+           +Q+  LQR   +L+++  +F+   
Sbjct: 1170 AEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEI 1229

Query: 146  TNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSE 205
             +L       +S+    ++++    E+++ E   K  E    R LSE   Q+ +LQ  + 
Sbjct: 1230 DDLSSSME-SVSKSKANLEKICRTLEDQLSEARGKNEE--IQRSLSELTTQKSRLQTEAG 1286

Query: 206  PQPRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEP 265
               R         E  +   + L  SK      + E+    KRQ+E EE      +    
Sbjct: 1287 ELSR-------QLEEKESIVSQLSRSKQAFTQQTEEL----KRQLE-EENKAKNALAHAL 1334

Query: 266  QRDRLPQEPGREQVVEDRPVGG---RGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQ 322
            Q  R   +  REQ  E++       R    A       + +      Q   E+E  ++  
Sbjct: 1335 QSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1394

Query: 323  LVIPDGQEEEQEA-----AGEGRNQQKLRGE-DDYNMDENEAESETDKQAALAGNDRNID 376
                   EE+ EA     A   + +Q+L+GE +D  +D   A S     AAL    RN D
Sbjct: 1395 AQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANS---LAAALDKKQRNFD 1451



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 76/358 (21%), Positives = 143/358 (39%), Gaps = 46/358 (12%)

Query: 73   ELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVN---NITTG----ERLIRVLQDQLK 125
            ELEK R+Q++  ++     LE      + E+A ++     +T      +R I    ++++
Sbjct: 1526 ELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIE 1585

Query: 126  TLQRNYGR---LQQDVLQFQKNQTN----LERKFSYDLSQCINQMKEVKEQCEERIEEVT 178
             L+RNY R     Q  L  +    N    L++K   DL++   Q+     Q  E ++ + 
Sbjct: 1586 QLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLR 1645

Query: 179  K-----KGNEAVASRDLSENNDQRQQLQALSEPQPRLQA------AGLPHTEVPQGKGN- 226
                  K  +      L    D ++QL  +      LQA      A L  TE  +     
Sbjct: 1646 SVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQ 1705

Query: 227  --VLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQVVEDRP 284
              +  N + Q     +  ++ +K+++E  +  ++Q   E+  RD    E   ++ + D  
Sbjct: 1706 ELLDSNERVQLLHTQNTSLIHTKKKLE-TDLMQLQSEVEDASRDARNAEEKAKKAITDAA 1764

Query: 285  VGGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGEGRNQ-Q 343
            +       A EL +     A L   ++N E    +    +     E EQ A   G+ Q Q
Sbjct: 1765 M------MAEELKKEQDTSAHLERMKKNLEQTVKDLQHRL----DEAEQLALKGGKKQIQ 1814

Query: 344  KLR---GEDDYNMDENEAESETDKQAALAGNDRNID--VFNVEDQKRDTINLLDQREK 396
            KL     E ++ + E E +  T+    L   +R +    +  E+ +++ + L D  +K
Sbjct: 1815 KLETRIRELEFEL-EGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDK 1871



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 75/356 (21%), Positives = 143/356 (40%), Gaps = 34/356 (9%)

Query: 42   LQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQD 101
            L+ ++ +LE  + +    R  +E  K + +G+L+  +E +  +++    QL+   K    
Sbjct: 1028 LEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQ-QLDERLKKKDF 1086

Query: 102  EKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERK---FSYDLSQ 158
            E   L + +   + L    Q ++K LQ     L++++   +  +   E++   ++ +L +
Sbjct: 1087 EYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEE 1146

Query: 159  CINQMKEVKEQCEERIEEVTKKGNEAV-ASRDLSENNDQRQQLQALSEPQPRLQAAGL-P 216
               +++E       +IE   K+  E +   RDL E   Q + + A    +     A L  
Sbjct: 1147 LSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGE 1206

Query: 217  HTEVPQGKGNVLGNSKSQTP------APSSEVVLDSKRQVEK------EETNEIQVVNEE 264
              +  Q     L   KS+        + S E V  SK  +EK      ++ +E +  NEE
Sbjct: 1207 QIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEE 1266

Query: 265  PQR--DRLPQEPGREQVVEDRPVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQ 322
             QR    L  +  R Q              AGEL +  + + ++ VSQ +   +   +  
Sbjct: 1267 IQRSLSELTTQKSRLQT------------EAGELSRQLEEKESI-VSQLSRSKQAFTQQT 1313

Query: 323  LVIPDGQEEEQEAAGE-GRNQQKLRGEDDYNMDENEAESETDKQAALAGNDRNIDV 377
              +    EEE +A        Q  R + D   ++ E E E   +   A +  N +V
Sbjct: 1314 EELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEV 1369



 Score = 34.3 bits (77), Expect = 0.21
 Identities = 31/138 (22%), Positives = 59/138 (42%), Gaps = 8/138 (5%)

Query: 63   VELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNITTGERLIRVLQD 122
            VE + N  Q E+E+ R  L++ + +   +L     L  +E+  L++   T       L  
Sbjct: 1675 VERRANLLQAEVEELRATLEQTERAR--KLAEQELLDSNERVQLLHTQNTS------LIH 1726

Query: 123  QLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGN 182
              K L+ +  +LQ +V    ++  N E K    ++      +E+K++ +        K N
Sbjct: 1727 TKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1786

Query: 183  EAVASRDLSENNDQRQQL 200
                 +DL    D+ +QL
Sbjct: 1787 LEQTVKDLQHRLDEAEQL 1804


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
            sapiens]
          Length = 1938

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 81/378 (21%), Positives = 149/378 (39%), Gaps = 27/378 (7%)

Query: 41   DLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLE------- 93
            +LQ RI ELE  +      R  +E ++++   ELE+  E+L++   + + Q+E       
Sbjct: 1114 ELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREA 1173

Query: 94   SVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFS 153
               K+ +D +   + +  T   L +   D +  L      LQ+   + +K ++ L+ +  
Sbjct: 1174 EFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEID 1233

Query: 154  YDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAA 213
             D++  I  + + K   E     V  + +E  A     ++  Q Q +  L+  + RLQ  
Sbjct: 1234 -DMASNIEALSKSKSNIERTCRTVEDQFSEIKA-----KDEQQTQLIHDLNMQKARLQTQ 1287

Query: 214  GLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQE 273
                +   + K +++        A + ++  + KRQ+E EET     +    Q  R   +
Sbjct: 1288 NGELSHRVEEKESLISQLTKSKQALTQQLE-ELKRQME-EETKAKNAMAHALQSSRHDCD 1345

Query: 274  PGREQVVEDRPVGG---RGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQE 330
              REQ  E++       R    A       + +      Q   E+E  ++         E
Sbjct: 1346 LLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAE 1405

Query: 331  EEQEAAGE-----GRNQQKLRGEDDYNMDENEAESETDKQAALAGNDRNIDVFNVE-DQK 384
            E  E A        + +Q+L+GE +  M   + E      A L    RN D    E  QK
Sbjct: 1406 ENTETANSKCASLEKTKQRLQGEVEDLM--RDLERSHTACATLDKKQRNFDKVLAEWKQK 1463

Query: 385  RDTINL-LDQREKRNHTL 401
             D     L+  +K + +L
Sbjct: 1464 LDESQAELEAAQKESRSL 1481



 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 71/378 (18%), Positives = 152/378 (40%), Gaps = 27/378 (7%)

Query: 41   DLQTRIMELEGRVRRAAAERGA-VELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLY 99
            DL   + E+  R+  A+    A +E+ K   + E +K R  L++    H     ++ K  
Sbjct: 1142 DLARELEEISERLEEASGATSAQIEMNKKR-EAEFQKMRRDLEEATLQHEATAATLRKKQ 1200

Query: 100  QDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQC 159
             D  A L   I   +R+ + L+ +   L+     +  ++    K+++N+ER       Q 
Sbjct: 1201 ADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQ- 1259

Query: 160  INQMKEVKEQCEERIEEVT-KKGNEAVASRDLSENNDQRQQL--------QALSEPQPRL 210
             +++K   EQ  + I ++  +K      + +LS   ++++ L        QAL++    L
Sbjct: 1260 FSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEEL 1319

Query: 211  QAAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRL 270
            +      T+      + L +S+        +   + +++ + E    +   N E  + R 
Sbjct: 1320 KRQMEEETKAKNAMAHALQSSRHDCDLLREQY--EEEQEAKAELQRALSKANSEVAQWRT 1377

Query: 271  PQEPGR----EQVVEDRPVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIP 326
              E       E++ E +    +    A E  +T   + A S+ +    ++G   D  ++ 
Sbjct: 1378 KYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCA-SLEKTKQRLQGEVED--LMR 1434

Query: 327  DGQEEEQEAAG---EGRNQQKLRGEDDYNMDENEAESETDKQAALAGNDRNIDVFNVEDQ 383
            D +      A    + RN  K+  E    +DE++AE E    A       + ++F + + 
Sbjct: 1435 DLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEA---AQKESRSLSTELFKMRNA 1491

Query: 384  KRDTINLLDQREKRNHTL 401
              + ++ L+   + N  L
Sbjct: 1492 YEEVVDQLETLRRENKNL 1509



 Score = 36.6 bits (83), Expect = 0.041
 Identities = 49/247 (19%), Positives = 104/247 (42%), Gaps = 20/247 (8%)

Query: 41   DLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSS------HNFQLES 94
            DL+    +LEG ++ +      +E  K + + +L+K+  +L ++Q+       H+ Q + 
Sbjct: 1051 DLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQK 1110

Query: 95   VNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQ---KNQTNLERK 151
              K  Q     L   I     L   ++ Q   L R    + + + +       Q  + +K
Sbjct: 1111 KIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKK 1170

Query: 152  FSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQL-QALSEPQPRL 210
               +  +    ++E   Q E     + KK  ++VA  +L E  D  Q++ Q L + +  L
Sbjct: 1171 REAEFQKMRRDLEEATLQHEATAATLRKKQADSVA--ELGEQIDNLQRVKQKLEKEKSEL 1228

Query: 211  QAAGLPHTEVPQGKGNVLGNSKSQTPAP-SSEVVLDSKRQVEKEETNEIQVVNE-EPQRD 268
            +       E+     N+   SKS++    +   V D   +++ ++  + Q++++   Q+ 
Sbjct: 1229 K------MEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKA 1282

Query: 269  RLPQEPG 275
            RL  + G
Sbjct: 1283 RLQTQNG 1289



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 28/131 (21%), Positives = 60/131 (45%), Gaps = 5/131 (3%)

Query: 42   LQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQD 101
            L+ +  +LEG + +    R  +E  K + +G+L+  +E +  +++    Q+E   K  + 
Sbjct: 1031 LEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQ-QIEEKLKKKEF 1089

Query: 102  EKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCIN 161
            E + L   I   +      Q ++K LQ     L++++    + +  L  K     S    
Sbjct: 1090 ELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEI----EAEHTLRAKIEKQRSDLAR 1145

Query: 162  QMKEVKEQCEE 172
            +++E+ E+ EE
Sbjct: 1146 ELEEISERLEE 1156



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 81/399 (20%), Positives = 155/399 (38%), Gaps = 61/399 (15%)

Query: 42   LQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQD 101
            LQ  + +L   + R+      ++ K+  F   L + +++LD+ Q+    +LE+  K  + 
Sbjct: 1425 LQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQA----ELEAAQKESRS 1480

Query: 102  EKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDV-------------LQFQKNQTNL 148
                L       E ++    DQL+TL+R    LQ+++             LQ  +    L
Sbjct: 1481 LSTELFKMRNAYEEVV----DQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKL 1536

Query: 149  ERKFSYDLSQCINQMKEVKEQCEERI-----------EEVTKKGNEAVASRDLSENNDQR 197
              +   DL   + +++   E  E +I            E+ +K  E     +  + N QR
Sbjct: 1537 VEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQR 1596

Query: 198  --QQLQALSEPQPRLQAAGLPHTEVPQGKGN----VLGNSKSQT------------PAPS 239
              + LQ++ + + R +   L   +  +G  N     LG+S  Q                 
Sbjct: 1597 AAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKD 1656

Query: 240  SEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQT 299
            S++ LD   +  ++   ++ +V  E +   L +E    +V  ++    R       L  +
Sbjct: 1657 SQLHLDDALRSNEDLKEQLAIV--ERRNGLLLEELEEMKVALEQTERTRRLSEQELLDAS 1714

Query: 300  PQVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGEGRN--QQKLRGEDDYNMDENE 357
             +VQ  L  SQ    +   ++ +  I   Q E + +  E RN  ++  +   D  M   E
Sbjct: 1715 DRVQ--LLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEE 1772

Query: 358  AESETDKQAALAGNDRNIDVFNVEDQKRDTINLLDQREK 396
             + E D  A L    +N+     E   +D  + LD+ E+
Sbjct: 1773 LKKEQDTSAHLERMKKNL-----EQTVKDLQHRLDEAEQ 1806



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 67/379 (17%), Positives = 153/379 (40%), Gaps = 70/379 (18%)

Query: 41   DLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEK----QREQLDKIQSSHNFQLESVN 96
            DLQ  + E+EG +    ++   V+L+ ++ + EL++    + E++++++ +     E++ 
Sbjct: 1543 DLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQ 1602

Query: 97   KLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLE---RKFS 153
             +   E    + +     RL + ++  L  ++   G   + + + QK+   ++   +   
Sbjct: 1603 SVLDAE----IRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQ 1658

Query: 154  YDLSQCINQMKEVKEQCE----------ERIEEVTKKGNEAVASRDLSENNDQRQQLQAL 203
              L   +   +++KEQ            E +EE+     +   +R LSE        Q L
Sbjct: 1659 LHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSE--------QEL 1710

Query: 204  SEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNE 263
             +   R+Q   L H++                    +  ++++K+++E +       V  
Sbjct: 1711 LDASDRVQ---LLHSQ--------------------NTSLINTKKKLEADIAQCQAEVEN 1747

Query: 264  EPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQL 323
              Q  R  +E  ++ + +   +       A EL +     A L   ++N E    +    
Sbjct: 1748 SIQESRNAEEKAKKAITDAAMM-------AEELKKEQDTSAHLERMKKNLEQTVKDLQHR 1800

Query: 324  VIPDGQEEEQEAAGEGRNQQKLRGEDDYNMDENEAESETDKQA-ALAG---NDRNID--V 377
            +     +E ++ A +G  +Q  + E+     ENE + E  + A AL G    +R +    
Sbjct: 1801 L-----DEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMT 1855

Query: 378  FNVEDQKRDTINLLDQREK 396
            +  E+  ++ + L D  +K
Sbjct: 1856 YQAEEDHKNILRLQDLVDK 1874



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 32/152 (21%), Positives = 64/152 (42%), Gaps = 18/152 (11%)

Query: 41   DLQTRIMELEGRVRRAAAER-GAVELKKNEFQGELE-KQREQLDKIQSSHNFQLESVNKL 98
            DLQ R+ E E    +   ++   +E +  E + EL+ +Q+   + ++ +H ++ +     
Sbjct: 1796 DLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMT 1855

Query: 99   YQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQ 158
            YQ E+           + I  LQD +        +LQ  V  +++     E + +  LS+
Sbjct: 1856 YQAEE---------DHKNILRLQDLVD-------KLQAKVKSYKRQAEEAEEQANTQLSR 1899

Query: 159  CINQMKEVKEQCEERIEEVTKKGNEAVASRDL 190
            C     E++E  E      ++       SRD+
Sbjct: 1900 CRRVQHELEEAAERADIAESQVNKLRAKSRDV 1931


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 79/351 (22%), Positives = 146/351 (41%), Gaps = 43/351 (12%)

Query: 41   DLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLE------- 93
            +LQT+I +L+ ++      R  +E ++ +   +L    E+L+++  S   QLE       
Sbjct: 1122 ELQTQIKDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQET 1181

Query: 94   SVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFS 153
               KL++D +   ++  TT   L +   D L  L+     LQQ   + +K++++L+ +  
Sbjct: 1182 KFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVD 1241

Query: 154  YDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRD---LSENNDQRQQLQALSEPQPRL 210
             DL   + QM   K   E+      ++ +EA A  D      N+   Q+ +  SE     
Sbjct: 1242 -DLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSE----- 1295

Query: 211  QAAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVN--EEPQRD 268
                L   E  +   N L   KS      +  + D + Q+EKE  ++  + +  ++ QRD
Sbjct: 1296 SGEFLRRLEEKEALINQLSREKSN----FTRQIEDLRGQLEKETKSQSALAHALQKAQRD 1351

Query: 269  RLPQEPGREQVVEDRPVGGRGFGGAGELGQT-PQVQAAL---------SVSQENPEMEGP 318
                +  REQ  E++ V         EL +T  +V A +         +V Q   ++E  
Sbjct: 1352 ---CDLLREQYEEEQEV-------KAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDA 1401

Query: 319  ERDQLVIPDGQEEEQEAAGEGRNQQKLRGEDDYNMDENEAESETDKQAALA 369
            ++ +L I   +  E       RN    R      ++  +A S+  K  + A
Sbjct: 1402 KK-ELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAA 1451



 Score = 32.7 bits (73), Expect = 0.60
 Identities = 42/231 (18%), Positives = 95/231 (41%), Gaps = 31/231 (13%)

Query: 37   SRSVDLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVN 96
            S S +   R+ E E  + + + E+     +  + +G+LEK+ +                 
Sbjct: 1294 SESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETK----------------- 1336

Query: 97   KLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDL 156
                  ++ L + +   +R   +L++Q +  Q     L + + +          K+  ++
Sbjct: 1337 -----SQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNV 1391

Query: 157  SQCINQMKEVKEQCEERIEEVTKK---GNEAVASRDLSENNDQRQQLQALSE-PQPRLQA 212
             Q    +++ K++   R++E  +     N   AS + + +  Q +   ALS+  + R  A
Sbjct: 1392 IQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAA 1451

Query: 213  AGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLD-SKRQVEKEETNEIQVVN 262
            A L   ++  GK       K +     S+ +LD S+++V+   T  +++ N
Sbjct: 1452 ARLDQKQLQSGKALADWKQKHE----ESQALLDASQKEVQALSTELLKLKN 1498


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 73/371 (19%), Positives = 150/371 (40%), Gaps = 49/371 (13%)

Query: 38   RSVDLQTRIMELEGRVRRAAAERGAVELKKNEF--------QGE---------LEKQREQ 80
            R + L+ +I+  E R+   A E   +   K EF        QG+         L K+RE 
Sbjct: 2008 RKLSLEEKILLHEDRI--LAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRES 2065

Query: 81   LDKIQSSHNFQLESVNKLYQDEKAVLVNNIT---------TGERLIRVLQDQLKTLQRNY 131
            L K  +  N  L+++ KL +DE+ +    I            ER + + Q +L   + ++
Sbjct: 2066 LSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDF 2125

Query: 132  GRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLS 191
               + ++ + +K     +RK +  + + IN+    +E+  E   ++ +K +E +   +  
Sbjct: 2126 SEKRSELTKDEKKLARKQRKLANKMRRMINK----EEKMTEEESKLARKHSEVILDDEEE 2181

Query: 192  ENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLD------ 245
               ++ + +  L     + + A        +    V      +  +   E +LD      
Sbjct: 2182 GGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQE 2241

Query: 246  -----SKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQTP 300
                  + + E+EE  E + V EE + +R  +E G E+ VE      +      +  +  
Sbjct: 2242 SLSSEEEEEREEEEEREEEEVREE-EEERKEEEEGEEKQVEKEEEEKK---KKKKEKKKE 2297

Query: 301  QVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGE--GRNQQKLRGEDDYNMDENEA 358
            +VQ    V +E  E+   E  + +  + +EEE  +  E   R ++ L+ E  + + E   
Sbjct: 2298 EVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRR 2357

Query: 359  ESETDKQAALA 369
            +S   ++  L+
Sbjct: 2358 KSLRGRERVLS 2368


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 79/379 (20%), Positives = 154/379 (40%), Gaps = 29/379 (7%)

Query: 41   DLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLE------- 93
            +LQ RI ELE  +    A R   E ++++   ELE+  E+L++   + + Q+E       
Sbjct: 1114 ELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA 1173

Query: 94   SVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFS 153
               K+ +D +   + +  T   L +   D +  L      LQ+   + +K ++ ++ +  
Sbjct: 1174 EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1233

Query: 154  YDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAA 213
             DL+  +  + + K   E+    +     E   S   ++  +Q++ +  L+  + RLQ  
Sbjct: 1234 -DLASNMETVSKAKGNLEKMCRAL-----EDQLSEIKTKEEEQQRLINDLTAQRARLQTE 1287

Query: 214  GLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQE 273
               ++     K + L +  S+     ++ + + KRQ+E EE      +    Q  R   +
Sbjct: 1288 SGEYSRQLDEK-DTLVSQLSRGKQAFTQQIEELKRQLE-EEIKAKSALAHALQSSRHDCD 1345

Query: 274  PGREQVVEDRPVGG---RGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQE 330
              REQ  E++       R    A       + +      Q   E+E  ++         E
Sbjct: 1346 LLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAE 1405

Query: 331  EEQEA-----AGEGRNQQKLRGE-DDYNMDENEAESETDKQAALAGNDRNIDVFNVEDQK 384
            E  EA     A   + +Q+L+ E +D  +D    E      AAL    RN D    E ++
Sbjct: 1406 EHVEAVNAKCASLEKTKQRLQNEVEDLMID---VERTNAACAALDKKQRNFDKILAEWKQ 1462

Query: 385  R--DTINLLDQREKRNHTL 401
            +  +T   L+  +K + +L
Sbjct: 1463 KCEETHAELEASQKESRSL 1481



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 61/249 (24%), Positives = 111/249 (44%), Gaps = 26/249 (10%)

Query: 40   VDLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLY 99
            + L+ ++ +LEG + +    R  +E  K + +G+L+  +E    I++    QL+   K  
Sbjct: 1029 IKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQ-QLDEKLKKK 1087

Query: 100  QDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQC 159
            + E + L + I   + L   LQ ++K LQ     L++++   + ++   E++ S DLS+ 
Sbjct: 1088 EFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRS-DLSR- 1145

Query: 160  INQMKEVKEQCEE-------RIEEVTKKGNE-AVASRDLSENNDQRQQLQALSEPQPRLQ 211
              +++E+ E+ EE       +IE   K+  E     RDL E   Q +   A    +    
Sbjct: 1146 --ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADS 1203

Query: 212  AAGL-PHTEVPQGKGNVLGNSKSQTP------APSSEVVLDSKRQVEK------EETNEI 258
             A L    +  Q     L   KS+        A + E V  +K  +EK      ++ +EI
Sbjct: 1204 VAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEI 1263

Query: 259  QVVNEEPQR 267
            +   EE QR
Sbjct: 1264 KTKEEEQQR 1272



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 40/180 (22%), Positives = 72/180 (40%), Gaps = 28/180 (15%)

Query: 42   LQTRIMELEGRVRRAAAERGAVELKKNEFQGELE-----------------KQREQLDKI 84
            L  R+ + E  V    A+  ++E  K   Q E+E                 K++   DKI
Sbjct: 1397 LAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKI 1456

Query: 85   QSSHNFQLESVN---KLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQF 141
             +    + E  +   +  Q E   L   +   +       DQL+TL+R    LQQ++   
Sbjct: 1457 LAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDL 1516

Query: 142  QKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQ 201
             +      ++        I++++++K+Q E+   E+     EA AS +  E    R QL+
Sbjct: 1517 TEQIAEGGKR--------IHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLE 1568



 Score = 33.1 bits (74), Expect = 0.46
 Identities = 31/141 (21%), Positives = 64/141 (45%), Gaps = 14/141 (9%)

Query: 63   VELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNITTGERLIRVLQD 122
            VE + N  Q E+E+ R  L++ + S     + +  L   E+  L++   T       L +
Sbjct: 1678 VERRANLLQAEIEELRATLEQTERSRKIAEQEL--LDASERVQLLHTQNTS------LIN 1729

Query: 123  QLKTLQRNYGRLQ---QDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTK 179
              K L+ +  ++Q   +D++Q  +N     +K   D +    ++K+ ++     +E + K
Sbjct: 1730 TKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKK-EQDTSAHLERMKK 1788

Query: 180  KGNEAVASRDLSENNDQRQQL 200
               + V  +DL    D+ +QL
Sbjct: 1789 NLEQTV--KDLQHRLDEAEQL 1807



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 67/379 (17%), Positives = 146/379 (38%), Gaps = 57/379 (15%)

Query: 45   RIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKA 104
            RI ELE   ++   E+  ++    E +  LE +  ++ +IQ   N Q++S       EK 
Sbjct: 1526 RIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELN-QVKSEVDRKIAEKD 1584

Query: 105  VLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMK 164
              ++ +      IR+++    TL           ++ + +   L++K   DL++   Q+ 
Sbjct: 1585 EEIDQMKRNH--IRIVESMQSTLDAE--------IRSRNDAIRLKKKMEGDLNEMEIQLN 1634

Query: 165  EVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQ-AAGLPHTEVPQG 223
                   E +     +  +A+        +D  +  + L E    ++  A L   E+ + 
Sbjct: 1635 HANRMAAEALRNY--RNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEEL 1692

Query: 224  KGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEP-----------------Q 266
            +  +    +S+  A   + +LD+  +V+   T    ++N +                  Q
Sbjct: 1693 RATLEQTERSRKIA--EQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQ 1750

Query: 267  RDRLPQEPGREQVVEDRPVGGRGFGGAGELGQTPQVQAALSVSQENPEM-------EGPE 319
              R  +E  ++ + +   +       A EL +     A L   ++N E           E
Sbjct: 1751 EARNAEEKAKKAITDAAMM-------AEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE 1803

Query: 320  RDQLVIPDGQEEEQEAAGEGRNQQKLRGEDDYNMDENEAESETDKQAALAGNDRNID--V 377
             +QL +  G+++ Q+     R   +L GE      E+E +   +    L  ++R +    
Sbjct: 1804 AEQLALKGGKKQIQKLEARVR---ELEGE-----VESEQKRNVEAVKGLRKHERKVKELT 1855

Query: 378  FNVEDQKRDTINLLDQREK 396
            +  E+ +++ + L D  +K
Sbjct: 1856 YQTEEDRKNILRLQDLVDK 1874


>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
            sapiens]
          Length = 1939

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 82/384 (21%), Positives = 157/384 (40%), Gaps = 39/384 (10%)

Query: 41   DLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLE------- 93
            +LQ RI ELE  +    A R   E ++++   ELE+  E+L++   + + Q+E       
Sbjct: 1114 ELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA 1173

Query: 94   SVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFS 153
               K+ +D +   + +  T   L +   D +  L      LQ+   + +K ++ L+ + +
Sbjct: 1174 EFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQKLEKEKSELKMEIN 1233

Query: 154  YDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAA 213
             DL+  +  + + K   E+    +     E   S   ++  +Q++ +  LS  + RL   
Sbjct: 1234 -DLASNMETVSKAKANFEKMCRTL-----EDQLSEIKTKEEEQQRLINELSAQKARL--- 1284

Query: 214  GLPHTEVPQ-----GKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRD 268
               HTE  +      + + + +  S+     ++ + + KRQ+E EET     +    Q  
Sbjct: 1285 ---HTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLE-EETKAKSTLAHALQSA 1340

Query: 269  RLPQEPGREQVVEDRPVGG---RGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVI 325
            R   +  REQ  E++       RG   A       + +      Q   E+E  ++     
Sbjct: 1341 RHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400

Query: 326  PDGQEEEQEA-----AGEGRNQQKLRGE-DDYNMDENEAESETDKQAALAGNDRNIDVFN 379
                EE  EA     A   + +Q+L+ E +D  +D    E       AL    RN D   
Sbjct: 1401 LQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMID---VERSNAACIALDKKQRNFDKVL 1457

Query: 380  VEDQKR--DTINLLDQREKRNHTL 401
             E +++  +T   L+  +K + +L
Sbjct: 1458 AEWKQKYEETQAELEASQKESRSL 1481



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 74/337 (21%), Positives = 132/337 (39%), Gaps = 64/337 (18%)

Query: 40   VDLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLY 99
            +DL+    +LEG ++ A            E   + E  ++QL++      F++ ++    
Sbjct: 1050 MDLERAKRKLEGDLKLA-----------QESTMDTENDKQQLNEKLKKKEFEMSNLQGKI 1098

Query: 100  QDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQC 159
            +DE+A+ +            LQ ++K LQ     L++++   + ++   E++ S DLS+ 
Sbjct: 1099 EDEQALAIQ-----------LQKKIKELQARIEELEEEIEAERASRAKAEKQRS-DLSR- 1145

Query: 160  INQMKEVKEQCEE-------RIEEVTKKGNE-AVASRDLSENNDQRQQLQALSEPQPRLQ 211
              +++E+ E+ EE       +IE   K+  E     RDL E+  Q +   A    +    
Sbjct: 1146 --ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADS 1203

Query: 212  AAGL-PHTEVPQGKGNVLGNSKSQTP------APSSEVVLDSKRQVEK------EETNEI 258
             A L    +  Q     L   KS+        A + E V  +K   EK      ++ +EI
Sbjct: 1204 VAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEI 1263

Query: 259  QVVNEEPQR---------DRLPQEPGREQVVEDRPVGGRGFGGAGELGQTPQVQAALSVS 309
            +   EE QR          RL  E G      D           G+   T Q++      
Sbjct: 1264 KTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQL 1323

Query: 310  QENPE--------MEGPERDQLVIPDGQEEEQEAAGE 338
            +E  +        ++    D  ++ +  EEEQEA  E
Sbjct: 1324 EEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAE 1360



 Score = 37.7 bits (86), Expect = 0.019
 Identities = 74/371 (19%), Positives = 157/371 (42%), Gaps = 54/371 (14%)

Query: 41   DLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQ----REQLDKIQSSHNFQLESVN 96
            +LQT + E E  +     +   ++L+ N+ + E++++     E+LD+++ +H   +ES+ 
Sbjct: 1543 ELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQ 1602

Query: 97   KLYQDEKAVLVNNITTGERLIRVLQDQLKTLQ---RNYGRLQQDVLQFQKNQTNLERKFS 153
                 E    + +     R+ + ++  L  ++    +  R   + L+  +N   + +   
Sbjct: 1603 STLDAE----IRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQ 1658

Query: 154  YDLSQCINQMKEVKEQ---CEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRL 210
              L   I    ++KEQ    E R   +  +  E  AS + +E   ++   Q L +   R+
Sbjct: 1659 LHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERG-RKMAEQELLDASERV 1717

Query: 211  QAAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRL 270
            Q   L HT+                    +  ++++K+++E  + ++IQ   E+  ++  
Sbjct: 1718 Q---LLHTQ--------------------NTSLINTKKKLE-TDISQIQGEMEDIVQEAR 1753

Query: 271  PQEPGREQVVEDRPVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQE 330
              E   ++ + D  +       A EL +     A L   ++N  ME   +D  +  D  E
Sbjct: 1754 NAEEKAKKAITDAAM------MAEELKKEQDTSAHLERMKKN--MEQTVKDLQLRLD--E 1803

Query: 331  EEQEAAGEGRNQ-QKLRGEDDYNMDENEAESETDKQA--ALAGNDRNID--VFNVEDQKR 385
             EQ A   G+ Q QKL         E E+E + + +A   L  ++R +    +  E+ ++
Sbjct: 1804 AEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRK 1863

Query: 386  DTINLLDQREK 396
            + + L D  +K
Sbjct: 1864 NILRLQDLVDK 1874



 Score = 35.4 bits (80), Expect = 0.092
 Identities = 38/160 (23%), Positives = 75/160 (46%), Gaps = 16/160 (10%)

Query: 42   LQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQD 101
            LQ  + +L   V R+ A   A++ K+  F   L + +++ ++ Q+    +LE+  K    
Sbjct: 1425 LQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQA----ELEASQK---- 1476

Query: 102  EKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCIN 161
            E   L   +   +       D L+TL+R    LQQ++       ++L  + + +  + I+
Sbjct: 1477 ESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEI-------SDLTEQIA-EGGKHIH 1528

Query: 162  QMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQ 201
            ++++VK+Q +    E+     EA AS +  E    R QL+
Sbjct: 1529 ELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRIQLE 1568



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 63/347 (18%), Positives = 134/347 (38%), Gaps = 34/347 (9%)

Query: 35   ASSRSVDLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLES 94
            +   S  L T + +++     +      ++ +    Q E+    EQ+ +    H  +LE 
Sbjct: 1474 SQKESRSLSTELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAE-GGKHIHELEK 1532

Query: 95   VNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFS- 153
            V K    EK+ L  ++   E           +L+   G++ +  L+  + ++ ++RK + 
Sbjct: 1533 VKKQLDHEKSELQTSLEEAE----------ASLEHEEGKILRIQLELNQVKSEIDRKIAE 1582

Query: 154  --YDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQ 211
               +L Q       V E  +  ++   +  N+A+  +   E +        L+E + +L 
Sbjct: 1583 KDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGD--------LNEMEIQLN 1634

Query: 212  AAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLP 271
             A     E  +   N  G  K       +++ LD   + + +   ++ +V  E + + + 
Sbjct: 1635 HANRQAAEALRNLRNTQGILK------DTQLHLDDAIRGQDDLKEQLAMV--ERRANLMQ 1686

Query: 272  QEPGREQVVEDRPVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQEE 331
             E    +   +R   GR       L  + +VQ  L  +Q    +   ++ +  I   Q E
Sbjct: 1687 AEVEELRASLERTERGRKMAEQELLDASERVQ--LLHTQNTSLINTKKKLETDISQIQGE 1744

Query: 332  EQEAAGEGRN--QQKLRGEDDYNMDENEAESETDKQAALAGNDRNID 376
             ++   E RN  ++  +   D  M   E + E D  A L    +N++
Sbjct: 1745 MEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1791


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 436

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 66/316 (20%), Positives = 138/316 (43%), Gaps = 54/316 (17%)

Query: 45  RIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKA 104
           ++ E EG+VR    +    E +  E +G++ +Q EQ+ +       Q E + K  Q+E+ 
Sbjct: 172 QVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGE-------QEEQMQK--QEEQ- 221

Query: 105 VLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMK 164
                   GE+     ++Q++  +   G  Q++ +Q Q+ Q    +K    + +   QM+
Sbjct: 222 -------MGEQ-----EEQMRKQEEQMGE-QEEQVQKQEEQV---QKQEEQMRKQEEQMR 265

Query: 165 EVKEQCEERIEEVTKKGNEAVASRDLSENNDQ-RQQLQAL--SEPQPRLQAAGLPHTEVP 221
           E +EQ  E+ E++ K+  +        E  +Q R+Q + +   E Q R Q   +   E  
Sbjct: 266 EQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQ 325

Query: 222 QGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQVVE 281
            GK       + +      E + + K Q+ K+E    + + E+ ++ +  +E  R+Q  +
Sbjct: 326 MGK-------QEEQMWEQKEQMWEQKEQMWKQE----EQMGEQEEQMQKQEEQVRKQEEQ 374

Query: 282 DRPVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGEGRN 341
            R              Q  Q++      ++  E  G +++Q+     Q  EQE    G  
Sbjct: 375 MRK-------------QEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQ-MGEQ 420

Query: 342 QQKLRGEDDYNMDENE 357
           ++++R ++++  ++ E
Sbjct: 421 KEQMRKQEEHMGEQKE 436



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 65/326 (19%), Positives = 131/326 (40%), Gaps = 31/326 (9%)

Query: 48  ELEGRVRRAAAERGAVELKKNEFQGELEKQREQL--DKIQSSHNFQLESVNKLYQDEKAV 105
           EL+ +      E   VE +K+E Q  +++ + +L  DKI      Q+       ++++  
Sbjct: 8   ELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEG- 66

Query: 106 LVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKE 165
               +   E  +R  + Q++  Q    R Q+  ++ Q+ Q    R+    + +   Q++E
Sbjct: 67  ---QVREQEGQVREQEGQVRE-QEGQVREQEGQVREQEGQV---REQEGQVREQEGQVRE 119

Query: 166 VKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTE--VPQG 223
            + Q  E+  +V ++  E        +  +Q  Q++   E Q R Q   +   E  V + 
Sbjct: 120 QEGQVREQEGQVREQ--EGQVREQEGQVREQEGQVRE-QEGQVREQEGQVREQEGQVREQ 176

Query: 224 KGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQVVEDR 283
           +G V    + Q      ++     +  E+EE    Q    + Q +++ ++  + +  E++
Sbjct: 177 EGQVR-EQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ 235

Query: 284 PVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQEEEQE----AAGEG 339
                     GE  Q  QVQ      Q+  E    + +Q+   + Q  EQE       E 
Sbjct: 236 ---------MGE--QEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQ 284

Query: 340 RNQQKLRGEDDYNMDENEAESETDKQ 365
             Q++  GE +  M E E +    ++
Sbjct: 285 TEQEEQTGEQEEQMREQEEQMREQEE 310


>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 75/382 (19%), Positives = 149/382 (39%), Gaps = 27/382 (7%)

Query: 35   ASSRSVDLQTRIMELEGRVRRAAAERGA-VELKKNEFQGELEKQREQLDKIQSSHNFQLE 93
            A  +  DL   + E+  R+  A     A +E+ K   + E +K R  L++    H     
Sbjct: 1138 AEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKR-EAEFQKMRRDLEEATLQHEATAA 1196

Query: 94   SVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFS 153
            ++ K + D  A L   I   +R+ + L+ +   ++     L  +V    K + NLE K  
Sbjct: 1197 TLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLE-KMC 1255

Query: 154  YDLSQCINQMKEVKEQCEERIEEVT-KKGNEAVASRDLSENNDQRQQL--------QALS 204
              L   ++++K  +E+ +  I ++T ++G     S + S   D+++ L        QA +
Sbjct: 1256 RTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFT 1315

Query: 205  EPQPRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQ----V 260
            +    L+       +      + L +S+          +L  + + E+E   E+Q     
Sbjct: 1316 QQIEELKRQLEEEIKAKNALAHALQSSRHDCD------LLREQYEEEQESKAELQRALSK 1369

Query: 261  VNEEPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQ--TPQVQAALSVSQENPEMEGP 318
             N E  + R   E    Q  E+     +      +  +     V A  +  ++  +    
Sbjct: 1370 ANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQN 1429

Query: 319  ERDQLVIPDGQEEEQEAA--GEGRNQQKLRGEDDYNMDENEAESETDKQAALAGNDRNID 376
            E + L++   +     AA   + RN  K+  E     +E  AE E  ++ A +       
Sbjct: 1430 EVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFK 1489

Query: 377  VFNVEDQKRDTINLLDQREKRN 398
            + N  ++  D +  L +RE +N
Sbjct: 1490 IKNAYEESLDQLETL-KRENKN 1510



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 75/352 (21%), Positives = 139/352 (39%), Gaps = 27/352 (7%)

Query: 41   DLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLE------- 93
            +LQ RI ELE  +    A R   E ++++   ELE+  E+L++   + + Q+E       
Sbjct: 1116 ELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA 1175

Query: 94   SVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFS 153
               K+ +D +   + +  T   L +   D +  L      LQ+   + +K ++ ++ +  
Sbjct: 1176 EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1235

Query: 154  YDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAA 213
             DL+  +  + + K   E+    +     E   S   S+  +Q++ +  L+  + RLQ  
Sbjct: 1236 -DLASNVETVSKAKGNLEKMCRTL-----EDQLSELKSKEEEQQRLINDLTAQRGRLQTE 1289

Query: 214  GLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQE 273
                +     K   L +  S+     ++ + + KRQ+E EE      +    Q  R   +
Sbjct: 1290 SGEFSRQLDEK-EALVSQLSRGKQAFTQQIEELKRQLE-EEIKAKNALAHALQSSRHDCD 1347

Query: 274  PGREQVVEDRPVGG---RGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQE 330
              REQ  E++       R    A       + +      Q   E+E  ++         E
Sbjct: 1348 LLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAE 1407

Query: 331  EEQEA-----AGEGRNQQKLRGE-DDYNMDENEAESETDKQAALAGNDRNID 376
            E  EA     A   + +Q+L+ E +D  +D    E      AAL    RN D
Sbjct: 1408 EHVEAVNAKCASLEKTKQRLQNEVEDLMLD---VERTNAACAALDKKQRNFD 1456



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 63/272 (23%), Positives = 119/272 (43%), Gaps = 48/272 (17%)

Query: 40   VDLQTRIMELEGRVRRAAAERGAVELKKNEFQGEL----------EKQREQLDKIQSSHN 89
            + L+ ++ +LEG + +    R  +E  K + +G+L          E +++QLD+      
Sbjct: 1031 IKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKE 1090

Query: 90   FQLESVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLE 149
            F++ ++    +DE+A+ +            LQ ++K LQ     L++++   + ++   E
Sbjct: 1091 FEISNLQSKIEDEQALGIQ-----------LQKKIKELQARIEELEEEIEAERASRAKAE 1139

Query: 150  RKFSYDLSQCINQMKEVKEQCEE-------RIEEVTKKGNE-AVASRDLSENNDQRQQLQ 201
            ++ S DLS+   +++E+ E+ EE       +IE   K+  E     RDL E   Q +   
Sbjct: 1140 KQRS-DLSR---ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATA 1195

Query: 202  ALSEPQPRLQAAGL-PHTEVPQGKGNVLGNSKSQTP------APSSEVVLDSKRQVEK-- 252
            A    +     A L    +  Q     L   KS+        A + E V  +K  +EK  
Sbjct: 1196 ATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMC 1255

Query: 253  ----EETNEIQVVNEEPQR--DRLPQEPGREQ 278
                ++ +E++   EE QR  + L  + GR Q
Sbjct: 1256 RTLEDQLSELKSKEEEQQRLINDLTAQRGRLQ 1287



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 37/160 (23%), Positives = 71/160 (44%), Gaps = 16/160 (10%)

Query: 42   LQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQD 101
            LQ  + +L   V R  A   A++ K+  F   L + +++ ++  +    +LE+  K    
Sbjct: 1427 LQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHA----ELEASQK---- 1478

Query: 102  EKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCIN 161
            E   L   +   +       DQL+TL+R    LQQ++    +      ++        I+
Sbjct: 1479 EARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR--------IH 1530

Query: 162  QMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQ 201
            +++++K+Q E+   E+     EA AS +  E    R QL+
Sbjct: 1531 ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLE 1570



 Score = 33.1 bits (74), Expect = 0.46
 Identities = 32/141 (22%), Positives = 64/141 (45%), Gaps = 14/141 (9%)

Query: 63   VELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNITTGERLIRVLQD 122
            VE + N  Q E+E+ R  L++ + S     + +  L   E+  L++   T       L +
Sbjct: 1680 VERRANLLQAEIEELRATLEQTERSRKIAEQEL--LDASERVQLLHTQNTS------LIN 1731

Query: 123  QLKTLQRNYGRLQ---QDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTK 179
              K L+ +  ++Q   +D+LQ  +N     +K   D +    ++K+ ++     +E + K
Sbjct: 1732 TKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK-EQDTSAHLERMKK 1790

Query: 180  KGNEAVASRDLSENNDQRQQL 200
               + V  +DL    D+ +QL
Sbjct: 1791 NMEQTV--KDLQLRLDEAEQL 1809


>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
            sapiens]
          Length = 1941

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 75/382 (19%), Positives = 149/382 (39%), Gaps = 27/382 (7%)

Query: 35   ASSRSVDLQTRIMELEGRVRRAAAERGA-VELKKNEFQGELEKQREQLDKIQSSHNFQLE 93
            A  +  DL   + E+  R+  A     A +E+ K   + E +K R  L++    H     
Sbjct: 1138 AEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKR-EAEFQKMRRDLEEATLQHEATAA 1196

Query: 94   SVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFS 153
            ++ K + D  A L   I   +R+ + L+ +   ++     L  +V    K + NLE K  
Sbjct: 1197 TLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLE-KMC 1255

Query: 154  YDLSQCINQMKEVKEQCEERIEEVT-KKGNEAVASRDLSENNDQRQQL--------QALS 204
              L   ++++K  +E+ +  I ++T ++G     S + S   D+++ L        QA +
Sbjct: 1256 RTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFT 1315

Query: 205  EPQPRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQ----V 260
            +    L+       +      + L +S+          +L  + + E+E   E+Q     
Sbjct: 1316 QQIEELKRQLEEEIKAKNALAHALQSSRHDCD------LLREQYEEEQESKAELQRALSK 1369

Query: 261  VNEEPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQ--TPQVQAALSVSQENPEMEGP 318
             N E  + R   E    Q  E+     +      +  +     V A  +  ++  +    
Sbjct: 1370 ANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQN 1429

Query: 319  ERDQLVIPDGQEEEQEAA--GEGRNQQKLRGEDDYNMDENEAESETDKQAALAGNDRNID 376
            E + L++   +     AA   + RN  K+  E     +E  AE E  ++ A +       
Sbjct: 1430 EVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFK 1489

Query: 377  VFNVEDQKRDTINLLDQREKRN 398
            + N  ++  D +  L +RE +N
Sbjct: 1490 IKNAYEESLDQLETL-KRENKN 1510



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 75/352 (21%), Positives = 139/352 (39%), Gaps = 27/352 (7%)

Query: 41   DLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLE------- 93
            +LQ RI ELE  +    A R   E ++++   ELE+  E+L++   + + Q+E       
Sbjct: 1116 ELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREA 1175

Query: 94   SVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFS 153
               K+ +D +   + +  T   L +   D +  L      LQ+   + +K ++ ++ +  
Sbjct: 1176 EFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEID 1235

Query: 154  YDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAA 213
             DL+  +  + + K   E+    +     E   S   S+  +Q++ +  L+  + RLQ  
Sbjct: 1236 -DLASNVETVSKAKGNLEKMCRTL-----EDQLSELKSKEEEQQRLINDLTAQRGRLQTE 1289

Query: 214  GLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQE 273
                +     K   L +  S+     ++ + + KRQ+E EE      +    Q  R   +
Sbjct: 1290 SGEFSRQLDEK-EALVSQLSRGKQAFTQQIEELKRQLE-EEIKAKNALAHALQSSRHDCD 1347

Query: 274  PGREQVVEDRPVGG---RGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQE 330
              REQ  E++       R    A       + +      Q   E+E  ++         E
Sbjct: 1348 LLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAE 1407

Query: 331  EEQEA-----AGEGRNQQKLRGE-DDYNMDENEAESETDKQAALAGNDRNID 376
            E  EA     A   + +Q+L+ E +D  +D    E      AAL    RN D
Sbjct: 1408 EHVEAVNAKCASLEKTKQRLQNEVEDLMLD---VERTNAACAALDKKQRNFD 1456



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 63/272 (23%), Positives = 119/272 (43%), Gaps = 48/272 (17%)

Query: 40   VDLQTRIMELEGRVRRAAAERGAVELKKNEFQGEL----------EKQREQLDKIQSSHN 89
            + L+ ++ +LEG + +    R  +E  K + +G+L          E +++QLD+      
Sbjct: 1031 IKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKE 1090

Query: 90   FQLESVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLE 149
            F++ ++    +DE+A+ +            LQ ++K LQ     L++++   + ++   E
Sbjct: 1091 FEISNLQSKIEDEQALGIQ-----------LQKKIKELQARIEELEEEIEAERASRAKAE 1139

Query: 150  RKFSYDLSQCINQMKEVKEQCEE-------RIEEVTKKGNE-AVASRDLSENNDQRQQLQ 201
            ++ S DLS+   +++E+ E+ EE       +IE   K+  E     RDL E   Q +   
Sbjct: 1140 KQRS-DLSR---ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATA 1195

Query: 202  ALSEPQPRLQAAGL-PHTEVPQGKGNVLGNSKSQTP------APSSEVVLDSKRQVEK-- 252
            A    +     A L    +  Q     L   KS+        A + E V  +K  +EK  
Sbjct: 1196 ATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMC 1255

Query: 253  ----EETNEIQVVNEEPQR--DRLPQEPGREQ 278
                ++ +E++   EE QR  + L  + GR Q
Sbjct: 1256 RTLEDQLSELKSKEEEQQRLINDLTAQRGRLQ 1287



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 37/160 (23%), Positives = 71/160 (44%), Gaps = 16/160 (10%)

Query: 42   LQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQD 101
            LQ  + +L   V R  A   A++ K+  F   L + +++ ++  +    +LE+  K    
Sbjct: 1427 LQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHA----ELEASQK---- 1478

Query: 102  EKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCIN 161
            E   L   +   +       DQL+TL+R    LQQ++    +      ++        I+
Sbjct: 1479 EARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR--------IH 1530

Query: 162  QMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQ 201
            +++++K+Q E+   E+     EA AS +  E    R QL+
Sbjct: 1531 ELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLE 1570



 Score = 33.1 bits (74), Expect = 0.46
 Identities = 32/141 (22%), Positives = 64/141 (45%), Gaps = 14/141 (9%)

Query: 63   VELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNITTGERLIRVLQD 122
            VE + N  Q E+E+ R  L++ + S     + +  L   E+  L++   T       L +
Sbjct: 1680 VERRANLLQAEIEELRATLEQTERSRKIAEQEL--LDASERVQLLHTQNTS------LIN 1731

Query: 123  QLKTLQRNYGRLQ---QDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTK 179
              K L+ +  ++Q   +D+LQ  +N     +K   D +    ++K+ ++     +E + K
Sbjct: 1732 TKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK-EQDTSAHLERMKK 1790

Query: 180  KGNEAVASRDLSENNDQRQQL 200
               + V  +DL    D+ +QL
Sbjct: 1791 NMEQTV--KDLQLRLDEAEQL 1809


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 84/379 (22%), Positives = 158/379 (41%), Gaps = 71/379 (18%)

Query: 43   QTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDK--IQSSHNFQ--LESVNKL 98
            Q ++ ++E ++     ++  V  +K E +G+L    +Q+++   +S    +  L+    L
Sbjct: 1605 QKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKAL 1664

Query: 99   YQDEKAVL--VNNITTGERLIRVLQDQL--------------KTLQRNYGRLQQDVLQFQ 142
              D + +L  + N    +R I  L++QL              K ++     L   +    
Sbjct: 1665 LADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIA 1724

Query: 143  KNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVA--SRDLSENNDQRQQL 200
            K +T LE + S  L +  N+++   E+ +E + E+ KK   AVA  SRDL++ ND + QL
Sbjct: 1725 KAKTALEEQLSR-LQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQL 1783

Query: 201  QALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSSE--VVLDSKRQVEKEETNEI 258
            +  ++ +  LQ       +  Q +   L  S       S +   + + + ++E E T   
Sbjct: 1784 EEANKEKQELQ----EKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERT--- 1836

Query: 259  QVVNEEPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGP 318
            QV   E    RL +    E++ E+R                        ++ EN E E  
Sbjct: 1837 QVKRLESLASRLKE--NMEKLTEERD---------------------QRIAAENREKEQN 1873

Query: 319  ERDQLVIPDGQEEEQEAAGEGRNQQKLRGEDDYNMDENEAESET-------------DKQ 365
            +R Q  + D +EE  E A +     + + E + +++  EA +++             D Q
Sbjct: 1874 KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQ 1933

Query: 366  AALAG---NDRNIDVFNVE 381
            AA+     +D N D+ N E
Sbjct: 1934 AAIEDEMESDENEDLINSE 1952



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 64/351 (18%), Positives = 142/351 (40%), Gaps = 37/351 (10%)

Query: 58   AERGAVELKKNEFQGELEKQREQLD----KIQSSHNFQLESVNKLYQD-----------E 102
            AER   E +  E Q + +  ++Q++    ++  +   +   +N    D           E
Sbjct: 1317 AERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYE 1376

Query: 103  KAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQ 162
            +AV   + T  +RL +  +D+L+  Q+N  +L++ +   Q +    +R            
Sbjct: 1377 RAVREVDFTK-KRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-----------A 1424

Query: 163  MKEVKEQCEERIEEV--TKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEV 220
            ++++K++C+    E+  TK   E    R+      QR+    LS+     Q   L   ++
Sbjct: 1425 LQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKL 1484

Query: 221  PQGKGNVLGNS---KSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGRE 277
             + K  +L  +   K Q      ++   +++ V  E   E+Q ++ +  +D       ++
Sbjct: 1485 QREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEA--ELQDISSQESKDEASLAKVKK 1542

Query: 278  QVVEDRPVGGRGFGGAGELGQTPQV--QAALSVSQENPEMEGPERDQLVIPDGQ-EEEQE 334
            Q+ +             E   T Q+  QA L +  E   M      ++   D + EE ++
Sbjct: 1543 QLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQ 1602

Query: 335  AAGEGRNQQKLRGEDDYNMDENEAESETDKQAALAGNDRNIDVFNVEDQKR 385
            +  +   Q +++ E++Y   +     + + +  LA     ++  + E +KR
Sbjct: 1603 SCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKR 1653


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 56/250 (22%), Positives = 109/250 (43%), Gaps = 31/250 (12%)

Query: 46  IMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAV 105
           + EL+ ++R A  E+ A+    N  QGE EK   Q + +      +LE+  K  Q++  V
Sbjct: 516 VHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQELVP-----ELENTIKNLQEKNGV 570

Query: 106 LVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNL------ERKFSYDLSQC 159
            + +++  + +++ L+ ++ +L          +    +   N       E +   +L + 
Sbjct: 571 YLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCEREERLILELGKK 630

Query: 160 INQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQR-----QQLQALSEPQPRLQAAG 214
           + Q  +   + E+++ E+T    E +  +D    NDQ+      Q++ LSE +  L A  
Sbjct: 631 VEQTIQYNSELEQKVNELTGGLEETLKEKD---QNDQKLEKLMVQMKVLSEDKEVLSA-- 685

Query: 215 LPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEE-----TNEIQVVNEEPQRDR 269
               +    + N L + K Q  +   EV L  K  V  +E       ++Q++ EE  +D 
Sbjct: 686 --EVKSLYEENNKLSSEKKQL-SRDLEVFLSQKEDVILKEHITQLEKKLQLMVEE--QDN 740

Query: 270 LPQEPGREQV 279
           L +    EQV
Sbjct: 741 LNKLLENEQV 750



 Score = 35.4 bits (80), Expect = 0.092
 Identities = 35/142 (24%), Positives = 68/142 (47%), Gaps = 14/142 (9%)

Query: 41   DLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQ 100
            +L+   ++ E +++  A     +E    E Q +L+K+++QL K       +LE V K   
Sbjct: 1102 ELEAEKLQKEQKIKEHATTVNELE----ELQVQLQKEKKQLQKTMQ----ELELVKK--D 1151

Query: 101  DEKAVLVN-NITTGERLIRVLQDQLKTLQRNYGRLQQDV-LQFQKNQTNLERKFSYDLSQ 158
             ++  L+N  I   ERL++ L  +L         L+Q++ +Q QK +T  E   S  L  
Sbjct: 1152 AQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITS--LQS 1209

Query: 159  CINQMKEVKEQCEERIEEVTKK 180
             + Q +E   + ++ + +  K+
Sbjct: 1210 SVQQYEEKNTKIKQLLVKTKKE 1231



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 26/124 (20%), Positives = 62/124 (50%), Gaps = 17/124 (13%)

Query: 73   ELEKQREQLD-KIQSSHNFQ--LESVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQR 129
            E EKQ EQLD + + ++NF+  +E + +  ++         +  E L+     +++TLQ 
Sbjct: 1025 EYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLA----RIETLQS 1080

Query: 130  NYGRLQQDVLQFQKNQTNLERKFSYDLSQ----------CINQMKEVKEQCEERIEEVTK 179
            N   L+  +L+ Q+ +  ++++   +  Q           +N+++E++ Q ++  +++ K
Sbjct: 1081 NAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEKKQLQK 1140

Query: 180  KGNE 183
               E
Sbjct: 1141 TMQE 1144



 Score = 29.6 bits (65), Expect = 5.1
 Identities = 42/190 (22%), Positives = 76/190 (40%), Gaps = 38/190 (20%)

Query: 53  VRRAAAERGAVELKKNEFQ------------GELEKQREQ-----LDKIQSSHNFQLESV 95
           + +A  E+  + LKK   +            G+  K+ EQ     + +I++  N +L +V
Sbjct: 83  LEKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKN-ELMAV 141

Query: 96  NKLYQDEKAVLVNNITTGERLIRVLQDQLK---TLQRNYGRLQQDVLQFQKNQTNLERKF 152
              Y ++KA L   +         L +QLK     + N  +LQ+++   +K +   E + 
Sbjct: 142 RSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEI---EKIRPGFEEQI 198

Query: 153 SYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQA 212
            Y         K++    +E+ E VT+  N       + E N Q  Q    S  +  LQ 
Sbjct: 199 LY-------LQKQLDATTDEKKETVTQLQN-------IIEANSQHYQKNINSLQEELLQL 244

Query: 213 AGLPHTEVPQ 222
             +   EV +
Sbjct: 245 KAIHQEEVKE 254


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 92/423 (21%), Positives = 167/423 (39%), Gaps = 76/423 (17%)

Query: 41   DLQTRIMELEGRVRRAAAERGAVELKKNEFQGELE-----KQREQLDKIQS--------- 86
            DL+ R+ E E R +   AE+  ++    E + +LE     +Q+ QL+K+ +         
Sbjct: 919  DLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEE 978

Query: 87   ------SHNFQLESVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQ 140
                    N +L    KL +D  A    N+T  E   + L       +     L++ + +
Sbjct: 979  EQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRR 1038

Query: 141  FQKNQTNLE---RKFSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVAS-----RDLSE 192
             +K +  LE   RK   D +   +Q+ E++ Q  E   ++ KK  E  A+      + ++
Sbjct: 1039 EEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQ 1098

Query: 193  NNDQRQQLQAL----SEPQPRLQAAGLPHTEVPQGK---GNVLGNSKSQ----TPAPSSE 241
             N   ++++ L    SE Q  L++      +  + K   G  L   K++      + +++
Sbjct: 1099 KNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQ 1158

Query: 242  VVLDSKRQVE---KEETNEIQVVNEEPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQ 298
              L SKR+ E    ++T E +    E Q   + Q+    Q VE+          A +L Q
Sbjct: 1159 QELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQK--HSQAVEEL---------AEQLEQ 1207

Query: 299  TPQVQAALSVSQENPEME----GPERDQLVIPDGQEEEQEAAGEGRNQQKLRGEDDYNMD 354
            T +V+A L  +++  E E      E   L+   G  E +    E + Q+    +  +N  
Sbjct: 1208 TKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQEL---QVKFNEG 1264

Query: 355  ENEAESETDKQAALAGNDRNI----------------DVFNVEDQKRDTINLLDQREKRN 398
            E       DK   L     N+                D   +E Q +DT  LL +  ++ 
Sbjct: 1265 ERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQK 1324

Query: 399  HTL 401
             +L
Sbjct: 1325 LSL 1327



 Score = 37.0 bits (84), Expect = 0.032
 Identities = 38/166 (22%), Positives = 77/166 (46%), Gaps = 9/166 (5%)

Query: 41   DLQTRIMELEGRVRRAAAERGA-VELKKNEFQGEL---EKQREQLDKIQSSHNFQLESVN 96
            +LQ +  E E RVR   A++   ++++ +   G L   + +  +L K  S+   QL+   
Sbjct: 1256 ELQVKFNEGE-RVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQ 1314

Query: 97   KLYQDE---KAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFS 153
            +L Q+E   K  L   +   E      ++QL+  +     L++ +        ++++K  
Sbjct: 1315 ELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKME 1374

Query: 154  YDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQ 199
             D   C+   +EVK + ++ +E ++++  E VA+ D  E    R Q
Sbjct: 1375 -DSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQ 1419



 Score = 37.0 bits (84), Expect = 0.032
 Identities = 42/178 (23%), Positives = 78/178 (43%), Gaps = 15/178 (8%)

Query: 37   SRSVDLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQRE---QLDKIQSSHNFQLE 93
            S+  D Q  + E   +    + +   VE +KN F+ +LE++ E    L+K  ++ + Q+ 
Sbjct: 1308 SQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVA 1367

Query: 94   SVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRN-------YGRLQQDVLQFQKNQT 146
             + K  +D     V  + T E + R LQ  L+ L +        Y +L++   + Q+   
Sbjct: 1368 DMKKKMEDS----VGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELD 1423

Query: 147  NLERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALS 204
            +L     +      N  K+ K+  +   EE T     A   RD +E   + ++ +ALS
Sbjct: 1424 DLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYA-EERDRAEAEAREKETKALS 1480


>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
           sapiens]
          Length = 631

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 54/245 (22%), Positives = 111/245 (45%), Gaps = 30/245 (12%)

Query: 49  LEGRVRRAAAERGAVELKKNEFQGELEKQRE---QLDKIQSSHNFQLESVNKLYQDEKAV 105
           LEG++R A   R +++ +    + E  +QR+   +L+++Q      L+   K  +DE++V
Sbjct: 396 LEGQLREAEQARASMQAEMELKEEEAARQRQRIKELEEMQQRLQEALQLEVKARRDEESV 455

Query: 106 LVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKF---SYDLSQCINQ 162
            +       RL+   +++LK L +     ++ + + Q+ +  L+++    S  L Q   Q
Sbjct: 456 RI----AQTRLLEEEEEKLKQLMQLKEEQERYIERAQQEKEELQQEMAQQSRSLQQAQQQ 511

Query: 163 MKEV---KEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPR---------- 209
           ++EV   +++ +E +E   +K  +  AS ++   N Q  +L    EP  +          
Sbjct: 512 LEEVRQNRQRADEDVEAAQRKLRQ--ASTNVKHWNVQMNRLMHPIEPGDKRPVTSSSFSG 569

Query: 210 LQAAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDR 269
            Q   L H +    +    G+  ++TP+P+S     +++Q      +E       PQ D+
Sbjct: 570 FQPPLLAHRDSSLKRLTRWGSQGNRTPSPNS-----NEQQKSLNGGDEAPAPASTPQEDK 624

Query: 270 LPQEP 274
           L   P
Sbjct: 625 LDPAP 629


>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
          Length = 2115

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 74/366 (20%), Positives = 151/366 (41%), Gaps = 31/366 (8%)

Query: 41  DLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQ 100
           DL+T   +++ ++ + + E G +  K  EF   L++ ++ L+++   H+       + + 
Sbjct: 301 DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHS----KATQEWL 356

Query: 101 DEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCI 160
           +++A L   ++   +  + L+++ + LQ    +L++ + Q Q N    + +   D+ Q  
Sbjct: 357 EKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLE 416

Query: 161 NQMKEV------KEQCEERIE--EVTKKGNEAVASRDLSENNDQRQQLQAL-SEPQPRLQ 211
              +E         Q + R+E  E  +   EA    +     +++QQL +L ++ Q  + 
Sbjct: 417 TLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSIS 476

Query: 212 AAGLPHTEVPQGKGNVLGNSKSQTPAPSSEV-VLDSKRQVEKEETNEIQVVNEEPQRDRL 270
                  E+ Q          +Q  + +SE+  L++  Q + +E   ++   +E Q    
Sbjct: 477 NLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLA 536

Query: 271 PQEPGREQVVEDRPVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQE 330
                +EQ  +            G   Q  Q+ ++L   +E    E  E+ +    D  +
Sbjct: 537 QTLQQQEQASQ------------GLRHQVEQLSSSLK-QKEQQLKEVAEKQEATRQDHAQ 583

Query: 331 EEQEAAGEGRNQQKLRGEDDYNMDENEAESETDKQAALAGNDRNIDVFNVEDQKRDTINL 390
           +   AA E   +  LR E D  + + EA  E +K A L    + + V N       T   
Sbjct: 584 QLATAAEE--REASLR-ERDAALKQLEA-LEKEKAAKLEILQQQLQVANEARDSAQTSVT 639

Query: 391 LDQREK 396
             QREK
Sbjct: 640 QAQREK 645



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 76/342 (22%), Positives = 142/342 (41%), Gaps = 48/342 (14%)

Query: 57   AAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNITTGERL 116
            A  R  VE  K E + ELE++R     +++    +L+ + + +Q E  VL   +      
Sbjct: 741  AETRSLVEQHKRE-RKELEEERAGRKGLEA----RLQQLGEAHQAETEVLRRELAEAMAA 795

Query: 117  IRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEE 176
                + + + L +     ++     Q+ +      F         Q+  +KE+CE+  +E
Sbjct: 796  QHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQ-------EQLMTLKEECEKARQE 848

Query: 177  VTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAA--GLPHTEV-PQGKGNVLGNSKS 233
            + +   +       SE    RQQ   L+E    L  A   +   EV  Q   + L   + 
Sbjct: 849  LQEAKEKVAGIESHSELQISRQQ-NELAELHANLARALQQVQEKEVRAQKLADDLSTLQE 907

Query: 234  QTPAPSSEVV-LDS--KRQVEKEETNEIQVVNEEPQR--DRLPQEPGREQVVEDRPVGGR 288
            +  A S EV  L++  ++  E++ET   ++V +EP R  DR P+    +Q        GR
Sbjct: 908  KMAATSKEVARLETLVRKAGEQQETASRELV-KEPARAGDRQPEWLEEQQ--------GR 958

Query: 289  GFGGAGELGQTPQVQAALSVSQENPEMEGPERDQL--VIPDGQEEEQEAAGEGR------ 340
             F            QAAL   +   E  G E ++L   + + Q ++QE  G+        
Sbjct: 959  QF---------CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARL 1009

Query: 341  NQQKLRGEDDYNMDENEAESETDKQAALAGNDRNIDVFNVED 382
             Q++ R + D  + E  A +E + +   A N++ ++   +++
Sbjct: 1010 TQERGRAQADLAL-EKAARAELEMRLQNALNEQRVEFATLQE 1050



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 47/198 (23%), Positives = 79/198 (39%), Gaps = 28/198 (14%)

Query: 41   DLQTRIMELEGRVRRAAAERGAVELK-----------KNEFQGELEK---QREQLDKIQS 86
            D +TR+ E++   +  A E   +  K           +  FQ E +K   Q EQL+  Q 
Sbjct: 1486 DAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQR 1545

Query: 87   SHNFQLESVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQT 146
                Q+E ++K   D            ++  +V Q +LK +Q   G  QQ+  + Q    
Sbjct: 1546 EQTKQVEELSKKLAD-----------SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLN 1594

Query: 147  NLERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVAS-RDLSENNDQRQQLQALSE 205
             L+ + S    Q     K   E+ +   +   ++  E     R L +   + ++L+A +E
Sbjct: 1595 ELQAQLS-QKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAE 1653

Query: 206  P-QPRLQAAGLPHTEVPQ 222
                 LQ AGL   E  Q
Sbjct: 1654 RLGHELQQAGLKTKEAEQ 1671



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 48/232 (20%), Positives = 94/232 (40%), Gaps = 26/232 (11%)

Query: 48   ELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLV 107
            E  GR      +  A+  + ++ + + +KQ+EQ D ++ S   + E  ++  +D      
Sbjct: 1110 EAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERS--LEAERASRAERDS----- 1162

Query: 108  NNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVK 167
                     +  LQ QL+   +  G  Q  +   Q+       K   D S+  +   E K
Sbjct: 1163 --------ALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ-DHSKAED---EWK 1210

Query: 168  EQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNV 227
             Q     +E  +K N  ++S +   +   RQ L+   E +  L+   +  +E  Q     
Sbjct: 1211 AQVARGRQEAERK-NSLISSLEEEVSILNRQVLEKEGESK-ELKRLVMAESEKSQKLEER 1268

Query: 228  LGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQV 279
            L   +++T + S+     S    E     E+Q + EE ++ R+  E  R+++
Sbjct: 1269 LRLLQAETASNSARAAERSSALRE-----EVQSLREEAEKQRVASENLRQEL 1315



 Score = 29.6 bits (65), Expect = 5.1
 Identities = 40/183 (21%), Positives = 71/183 (38%), Gaps = 22/183 (12%)

Query: 43   QTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSS----------HNFQL 92
            Q +   LE  +    A R   +      QG+LE++ ++L   QS+             ++
Sbjct: 1140 QEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKV 1199

Query: 93   ESVNKLYQDEKAVLVNNITTGER---LIRVLQDQLKTLQRNY-------GRLQQDVLQFQ 142
            +  +K   + KA +       ER   LI  L++++  L R           L++ V+   
Sbjct: 1200 QDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAES 1259

Query: 143  KNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQA 202
            +    LE +     ++  +      E+     EEV     EA   R  SEN   RQ+L +
Sbjct: 1260 EKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASEN--LRQELTS 1317

Query: 203  LSE 205
             +E
Sbjct: 1318 QAE 1320


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 83/377 (22%), Positives = 157/377 (41%), Gaps = 71/377 (18%)

Query: 43   QTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDK--IQSSHNFQ--LESVNKL 98
            Q ++ ++E ++     ++  V  +K E +G+L    +Q+++   +S    +  L+    L
Sbjct: 1605 QKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKAL 1664

Query: 99   YQDEKAVL--VNNITTGERLIRVLQDQL--------------KTLQRNYGRLQQDVLQFQ 142
              D + +L  + N    +R I  L++QL              K ++     L   +    
Sbjct: 1665 LADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIA 1724

Query: 143  KNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVA--SRDLSENNDQRQQL 200
            K +T LE + S  L +  N+++   E+ +E + E+ KK   AVA  SRDL++ ND + QL
Sbjct: 1725 KAKTALEEQLSR-LQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQL 1783

Query: 201  QALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSSE--VVLDSKRQVEKEETNEI 258
            +  ++ +  LQ       +  Q +   L  S       S +   + + + ++E E T   
Sbjct: 1784 EEANKEKQELQ----EKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERT--- 1836

Query: 259  QVVNEEPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGP 318
            QV   E    RL +    E++ E+R                        ++ EN E E  
Sbjct: 1837 QVKRLESLASRLKE--NMEKLTEERD---------------------QRIAAENREKEQN 1873

Query: 319  ERDQLVIPDGQEEEQEAAGEGRNQQKLRGEDDYNMDENEAESET-------------DKQ 365
            +R Q  + D +EE  E A +     + + E + +++  EA +++             D Q
Sbjct: 1874 KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQ 1933

Query: 366  AALAG---NDRNIDVFN 379
            AA+     +D N D+ N
Sbjct: 1934 AAIEDEMESDENEDLIN 1950



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 64/351 (18%), Positives = 142/351 (40%), Gaps = 37/351 (10%)

Query: 58   AERGAVELKKNEFQGELEKQREQLD----KIQSSHNFQLESVNKLYQD-----------E 102
            AER   E +  E Q + +  ++Q++    ++  +   +   +N    D           E
Sbjct: 1317 AERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYE 1376

Query: 103  KAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQ 162
            +AV   + T  +RL +  +D+L+  Q+N  +L++ +   Q +    +R            
Sbjct: 1377 RAVREVDFTK-KRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-----------A 1424

Query: 163  MKEVKEQCEERIEEV--TKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEV 220
            ++++K++C+    E+  TK   E    R+      QR+    LS+     Q   L   ++
Sbjct: 1425 LQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKL 1484

Query: 221  PQGKGNVLGNS---KSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGRE 277
             + K  +L  +   K Q      ++   +++ V  E   E+Q ++ +  +D       ++
Sbjct: 1485 QREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEA--ELQDISSQESKDEASLAKVKK 1542

Query: 278  QVVEDRPVGGRGFGGAGELGQTPQV--QAALSVSQENPEMEGPERDQLVIPDGQ-EEEQE 334
            Q+ +             E   T Q+  QA L +  E   M      ++   D + EE ++
Sbjct: 1543 QLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQ 1602

Query: 335  AAGEGRNQQKLRGEDDYNMDENEAESETDKQAALAGNDRNIDVFNVEDQKR 385
            +  +   Q +++ E++Y   +     + + +  LA     ++  + E +KR
Sbjct: 1603 SCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKR 1653


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 43/179 (24%), Positives = 73/179 (40%), Gaps = 22/179 (12%)

Query: 48   ELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLV 107
            EL  R++    E   V+++K     EL   +++L K+  S         K  Q  KA ++
Sbjct: 829  ELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAIL 888

Query: 108  NNITTGERLIRVLQDQLKT---------------------LQRNYGRLQQDVLQFQKNQT 146
            +   T + L   LQ Q++                      L+     +Q+ ++Q Q N  
Sbjct: 889  DLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQ-NTL 947

Query: 147  NLERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSE 205
                K    L   IN++K+  EQ +++IE +  +   AV  +   EN  Q+Q  QA  E
Sbjct: 948  KQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQE 1006



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 55/258 (21%), Positives = 116/258 (44%), Gaps = 43/258 (16%)

Query: 48   ELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAV-- 105
            +L+ ++ +AA E  A + K +  Q   EK +E   ++QS    +   +    QD K+V  
Sbjct: 995  KLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEE 1054

Query: 106  --------LVNN---ITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSY 154
                    L++N   I    +LI+ L+    TL+++  + +Q + +  K   +++++ S 
Sbjct: 1055 KLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSL 1114

Query: 155  DLSQCINQMKEVKE----QCEERIEEVTKKGNEAVASR--DLSENNDQRQQLQALSEPQP 208
               + +N+  ++ E    +C +  +E+TK   E  + +   + E  + +   Q L + + 
Sbjct: 1115 KEKELVNEKSKLAEIEEIKCRQE-KEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKL 1173

Query: 209  RLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRD 268
             L           QGK + L  +  Q     ++ +L  K QV+KEE        EE +++
Sbjct: 1174 EL-----------QGKADSLKAAVEQ--EKRNQQIL--KDQVKKEE--------EELKKE 1210

Query: 269  RLPQEPGREQVVEDRPVG 286
             + +E      ++++ VG
Sbjct: 1211 FIEKEAKLHSEIKEKEVG 1228



 Score = 37.7 bits (86), Expect = 0.019
 Identities = 32/173 (18%), Positives = 82/173 (47%), Gaps = 12/173 (6%)

Query: 34  IASSRSVDLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLE 93
           ++S + +D + ++ +L+ ++ R   +         E Q +L+K ++Q  + Q+       
Sbjct: 443 LSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTA 502

Query: 94  SVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFS 153
            + +   D + VL        R I     +++ L+    + ++++   +K + +L  K  
Sbjct: 503 KLREAQNDLEQVL--------RQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQ 554

Query: 154 YDLSQC--INQMKEVKEQCEERIEEVTKK-GNEAVASRDLSEN-NDQRQQLQA 202
               +   +NQ++E     +E++ ++T+K  N++ + +   EN +DQ Q+ +A
Sbjct: 555 AGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKA 607



 Score = 34.3 bits (77), Expect = 0.21
 Identities = 41/189 (21%), Positives = 86/189 (45%), Gaps = 24/189 (12%)

Query: 40  VDLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQRE-----QLDKIQSSHNFQLE- 93
           + L+ +  ELEG++++  A+   V+  K +   +L++QR+     +L   + S   ++E 
Sbjct: 719 LSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEK 778

Query: 94  ---SVNKLYQDEKAVLVNNI----TTGERLIRVLQDQLKTLQRN--------YGRLQQDV 138
              S  +L   +K+  + +I    T  E   ++L+   +TL +           R+Q  V
Sbjct: 779 EIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTV 838

Query: 139 LQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVAS-RDLSEN-NDQ 196
            + QK +   E   + +LS   +++ +V +  +    E  K+  +  A+  DL +   + 
Sbjct: 839 TELQKVKMEKEALMT-ELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKEL 897

Query: 197 RQQLQALSE 205
           + QLQ   E
Sbjct: 898 KHQLQVQME 906



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 4/95 (4%)

Query: 73   ELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYG 132
            ELEKQ + L          LE+  +  QDE+  L+     GE  I  LQ ++  LQR   
Sbjct: 1266 ELEKQTDDL----RGEIAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLD 1321

Query: 133  RLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVK 167
                 V +  +   +L+ K +  L++   +  EV+
Sbjct: 1322 NTTAAVQELGRENQSLQIKHTQALNRKWAEDNEVQ 1356



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 45/242 (18%), Positives = 93/242 (38%), Gaps = 37/242 (15%)

Query: 41  DLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQ 100
           DL  +I   EG      A    ++ K +  Q ++ +  E+L     SH    E+++   Q
Sbjct: 548 DLYAKIQAGEGET----AVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQ 603

Query: 101 DEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCI 160
           ++KA L           R  QD++ +L+ +                        +L+  +
Sbjct: 604 EQKAHL-----------RAAQDRVLSLETSVN----------------------ELNSQL 630

Query: 161 NQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEV 220
           N+ KE   Q + +I+  T+    A A++     + Q     A +  Q + Q      T++
Sbjct: 631 NESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQL 690

Query: 221 PQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQVV 280
            Q    +    +  +   S       K    +++T E++   ++ + D L  +  +EQ +
Sbjct: 691 DQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQAL 750

Query: 281 ED 282
           +D
Sbjct: 751 QD 752


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 83/379 (21%), Positives = 154/379 (40%), Gaps = 29/379 (7%)

Query: 41   DLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLE------- 93
            +LQ RI EL   +    A R   E ++++   ELE+  E+L++   + + Q+E       
Sbjct: 1113 ELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREA 1172

Query: 94   SVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFS 153
               KL +D +   + +      L +   D +  L      LQ+   + +K ++ L+ + +
Sbjct: 1173 EFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKME-T 1231

Query: 154  YDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAA 213
             DLS     + + K   E+    +     E   S   ++  +Q++ +  L+  + RLQ  
Sbjct: 1232 DDLSSNAEAISKAKGNLEKMCRSL-----EDQVSELKTKEEEQQRLINDLTAQRARLQTE 1286

Query: 214  GLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQE 273
               ++     K + L +  S++   S++ + + K Q+E EET     +    Q  R   +
Sbjct: 1287 AGEYSRQLDEK-DALVSQLSRSKQASTQQIEELKHQLE-EETKAKNALAHALQSSRHDCD 1344

Query: 274  PGREQVVEDRPVGG---RGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQE 330
              REQ  E++       R    A       + +      Q   E+E  ++         E
Sbjct: 1345 LLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAE 1404

Query: 331  EEQEA-----AGEGRNQQKLRGE-DDYNMDENEAESETDKQAALAGNDRNID-VFNVEDQ 383
            E  EA     A   + +Q+L+ E +D  +D    E      AAL    RN D V +   Q
Sbjct: 1405 EHVEAVNAKCASLEKTKQRLQNEVEDLMLD---VERSNAACAALDKKQRNFDKVLSEWKQ 1461

Query: 384  K-RDTINLLDQREKRNHTL 401
            K  +T   L+  +K + +L
Sbjct: 1462 KYEETQAELEASQKESRSL 1480



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 60/265 (22%), Positives = 112/265 (42%), Gaps = 46/265 (17%)

Query: 34   IASSRSVDLQTRIMELEGRVRRAAAERGAVELKKNEFQGEL----------EKQREQLDK 83
            I +     L+ ++ +LEG + +    R  +E  K + +G+L          E  ++QLD+
Sbjct: 1022 ILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDE 1081

Query: 84   IQSSHNFQLESVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQK 143
                  F++ ++    +DE+AV +            LQ ++K LQ     L +++   + 
Sbjct: 1082 KLEKKEFEISNLISKIEDEQAVEIQ-----------LQKKIKELQARIEELGEEIEAERA 1130

Query: 144  NQTNLERKFSYDLSQCINQMKEVKEQCEE-------RIEEVTKKGNE-AVASRDLSENND 195
            ++   E++ S DLS+   +++E+ E+ EE       ++E   K+  E     RDL E   
Sbjct: 1131 SRAKAEKQRS-DLSR---ELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATL 1186

Query: 196  QRQQLQALSEPQPRLQAAGLPH-----TEVPQGKGNVLGNSKSQTPAPSS--EVVLDSKR 248
            Q + + A    +     A L         V Q         K +T   SS  E +  +K 
Sbjct: 1187 QHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKG 1246

Query: 249  QVEK------EETNEIQVVNEEPQR 267
             +EK      ++ +E++   EE QR
Sbjct: 1247 NLEKMCRSLEDQVSELKTKEEEQQR 1271



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 40/160 (25%), Positives = 77/160 (48%), Gaps = 16/160 (10%)

Query: 42   LQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQD 101
            LQ  + +L   V R+ A   A++ K+  F   L + +++ ++ Q+    +LE+  K    
Sbjct: 1424 LQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQA----ELEASQK---- 1475

Query: 102  EKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCIN 161
            E   L   +   + +     DQL+TL+R    LQQ++       ++L  + +    Q I+
Sbjct: 1476 ESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEI-------SDLTEQIAEGGKQ-IH 1527

Query: 162  QMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQ 201
            +++++K+Q E+   E+     EA AS +  E    R QL+
Sbjct: 1528 ELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLE 1567



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 30/138 (21%), Positives = 58/138 (42%), Gaps = 8/138 (5%)

Query: 63   VELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNITTGERLIRVLQD 122
            VE + N  Q E+E+    L++ + S     + +  L   E+  L++   T       L +
Sbjct: 1677 VERRANLLQAEIEELWATLEQTERSRKIAEQEL--LDASERVQLLHTQNTS------LIN 1728

Query: 123  QLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGN 182
              K L+ +  +LQ +V +  +   N E K    ++      +E+K++ +        K N
Sbjct: 1729 TKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1788

Query: 183  EAVASRDLSENNDQRQQL 200
                 +DL    D+ +QL
Sbjct: 1789 LEQTVKDLQHRLDEAEQL 1806


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 79/339 (23%), Positives = 139/339 (41%), Gaps = 38/339 (11%)

Query: 45   RIMELEGRVRRAAAERGAV----ELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQ 100
            + +E E R+RR   ER  +    +L+  E + +L + R++  + +     + E   K  +
Sbjct: 1375 KFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFRE 1434

Query: 101  DEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQT----NLERKFSYDL 156
            +E+ V        ER     + QL+  +    R ++ +LQ ++ Q       +RKF  + 
Sbjct: 1435 EEQQVRRQE---RERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEE 1491

Query: 157  SQCINQMKEVKEQCEE-RIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGL 215
             Q   Q ++ K + +E R +E  +K  E    + L     QR+ LQ   E Q R Q  G 
Sbjct: 1492 QQLRRQERDRKFREQELRSQEPERKFLEE--EQQLHRQQRQRKFLQ--EEQQLRRQERGQ 1547

Query: 216  PHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQR------DR 269
               +    K       + Q      E  L  + +  K    E +V  +E +R       +
Sbjct: 1548 QRRQDRDRKFR----EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQ 1603

Query: 270  LPQEPGREQVVEDRPVGGRGFGGAGELGQTPQVQAA------LSVSQENPEMEGPERDQL 323
            L ++ G++Q+ ++R    R F    +L Q  + Q            +E P++   ER+Q 
Sbjct: 1604 LRRQEGQQQLRQERD---RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQ 1660

Query: 324  VIPDGQE---EEQEAAGEGRNQQKLRGEDDYNMDENEAE 359
            +  D      EE++   EG  QQ  R E D    E E +
Sbjct: 1661 LRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQ 1699



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 71/350 (20%), Positives = 142/350 (40%), Gaps = 28/350 (8%)

Query: 52  RVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNIT 111
           R+RR    R   E ++ E Q E  +Q+E+ ++ +     QL    +  ++++        
Sbjct: 299 RLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE 358

Query: 112 TGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCE 171
             E+ +R  Q++ +  Q+     Q    Q  + +  L R+      Q + + ++++ + +
Sbjct: 359 RREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418

Query: 172 ERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNS 231
            R E+  ++  E        E   + Q+L+   E + R        TE  + +       
Sbjct: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEER-RDWLKREEETERHEQE-----RR 472

Query: 232 KSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQVVEDRPVGGRGFG 291
           K Q      E   +   ++E+EE  E Q   E  Q+ R  QE  REQ ++ +        
Sbjct: 473 KQQLKRDQEEERRERWLKLEEEERREQQERRE--QQLRREQEERREQRLKRQE------- 523

Query: 292 GAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGEGRNQQKLRGEDDY 351
                 +  ++Q  L   Q+    +   R+QL+    + EE++   + R +Q+L+ E + 
Sbjct: 524 ------EEERLQQRLRSEQQLRREQEERREQLL----KREEEKRLEQERREQRLKREQEE 573

Query: 352 NMDENEAESETDKQAALAGNDRNIDVFNVEDQKRDTINLLDQREKRNHTL 401
             D+     E  +Q  L    R  +    +  KR+ +  L+Q E+R   L
Sbjct: 574 RRDQLLKREEERRQQRL---KREQEERLEQRLKREEVERLEQEERREQRL 620



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 66/338 (19%), Positives = 137/338 (40%), Gaps = 31/338 (9%)

Query: 50  EGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQL---ESVNKLYQDEKAVL 106
           E ++RR    R   E +++E + E E++ ++L + Q      L   E   +  Q+ +   
Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475

Query: 107 VNNITTGERLIRVLQDQLKTLQRNYGRLQQDVL--QFQKNQTNLERKFSYD-LSQCINQM 163
           +      ER  R L+ + +  +    R +Q +   Q ++ +  L+R+   + L Q +   
Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSE 535

Query: 164 KEVKEQCEERIEEVTKKGNEAVASRD----------------LSENNDQRQQLQALSEPQ 207
           ++++ + EER E++ K+  E    ++                L +  ++R+Q +   E +
Sbjct: 536 QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE 595

Query: 208 PRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQR 267
            RL+   L   EV + +       + +   P  E      +  E+EE  + Q+  E+ +R
Sbjct: 596 ERLEQR-LKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQER 654

Query: 268 --DRLPQEPGREQVVEDRPVGGRGFGGAGELGQTPQVQAALSVSQENP------EMEGPE 319
              RL +E   E++ +             EL +  Q QA   +    P      E E   
Sbjct: 655 REQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADA 714

Query: 320 RDQLVIPDGQEEEQEAAGEGRNQQKLRGEDDYNMDENE 357
           R   V    +++E +   + + +++ R E +    E E
Sbjct: 715 RQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEE 752



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 64/362 (17%), Positives = 148/362 (40%), Gaps = 29/362 (8%)

Query: 60  RGAVELKKNEFQGELEKQREQLDKI-QSSHNFQLESVNKLYQDEKAVLVNNITTGERLIR 118
           R  +EL++   + + +++RE+ D++ Q     +      + + E+  L       +R ++
Sbjct: 213 RELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ 272

Query: 119 VLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSY-------DLSQCINQMKEVKEQCE 171
             ++QL+ L+R   R ++   + Q+ +   E++          +  +   + +E +EQ E
Sbjct: 273 EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332

Query: 172 ERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNS 231
           ER E+  ++  E    + L    ++ ++ Q L   Q   +       E    +   L   
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRRE 392

Query: 232 KS--QTPAPSSEVVLDSKRQVEKEE----TNEIQVVNEEPQRDRLPQEPGREQVVEDRPV 285
           +   +      E  L  ++Q+ +E+      +++   EE + ++  ++  REQ ++    
Sbjct: 393 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQE 452

Query: 286 GGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGEGRNQQKL 345
             R +    E  +  + +      + + E E  ER   +  + + E+QE     R +Q+L
Sbjct: 453 ERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQE-----RREQQL 507

Query: 346 RGEDDYNMDENEAESE----------TDKQAALAGNDRNIDVFNVEDQKRDTINLLDQRE 395
           R E +   ++     E          +++Q      +R   +   E++KR      +QR 
Sbjct: 508 RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL 567

Query: 396 KR 397
           KR
Sbjct: 568 KR 569



 Score = 37.0 bits (84), Expect = 0.032
 Identities = 71/352 (20%), Positives = 137/352 (38%), Gaps = 44/352 (12%)

Query: 66   KKNEFQGELEKQREQL------DKIQSSHNFQLESVNKLYQDEKAVLVNNITTGERLIRV 119
            KK   + EL+++ EQL       + +     Q    ++L Q+E+ +L       ER  R 
Sbjct: 988  KKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE-----EREKRR 1042

Query: 120  LQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTK 179
            LQ++ +   R    LQQ+  Q    +    R+   +L +   + +E++++ E+ + E  +
Sbjct: 1043 LQERERQY-REEEELQQEEEQLLGEERETRRR--QELERQYRKEEELQQEEEQLLREEPE 1099

Query: 180  KGNEAVASRDLSENND-QRQQLQALSEPQPRLQAAGLPHT-----EVPQGKGNVLGNSKS 233
            K       R   E  + Q+++ Q L E + + +   L        EV Q +  +L     
Sbjct: 1100 KRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPE 1159

Query: 234  QTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQVVEDRPVGGRGFGGA 293
            +            ++++E++   E ++  EE Q  R  QE  R++         R +   
Sbjct: 1160 KR----------RRQELERQYREEEELQQEEEQLLREEQEKRRQE-------RERQYREE 1202

Query: 294  GELGQTPQVQAALSVSQEN-------PEMEGPERDQLVIPDGQEEEQEAAGEGRNQQKLR 346
             EL +  + Q      Q +       PE E   RD  V   G+E EQ    E    +  +
Sbjct: 1203 EELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQ 1262

Query: 347  GEDDYNMDENEAESETDKQAALAGNDRNIDVFNVEDQKRDTINLLDQREKRN 398
             + D      E +    +Q       R+      E  +R+      +R++++
Sbjct: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKS 1314



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 64/348 (18%), Positives = 130/348 (37%), Gaps = 44/348 (12%)

Query: 54   RRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQDEKAVLVNNITTG 113
            +R +A     E ++ + + E  +QREQ    +     Q     +  + E   L       
Sbjct: 782  QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE---- 837

Query: 114  ERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQ--------------C 159
            E+L R  +++ + LQ     LQ+D  + +  +   ++K+ + L +               
Sbjct: 838  EQLQR--RERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPAL 895

Query: 160  INQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTE 219
              Q+++ ++  +E  EE+ ++  E    ++      + +QLQ   E   R +       E
Sbjct: 896  QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE 955

Query: 220  VPQG--KGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGRE 277
              +   K   L   + Q      E     +R+ +  E  E+Q   EE Q  R  +E  R 
Sbjct: 956  RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ--QEEEQLLREEREKRRR 1013

Query: 278  QVVEDRPVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAG 337
            Q  E                   Q +    + QE  ++   ER++  + + + + +E   
Sbjct: 1014 QEWER------------------QYRKKDELQQEEEQLLREEREKRRLQERERQYREEEE 1055

Query: 338  EGRNQQKLRGEDDYNMDENEAESETDKQAALAGNDRNIDVFNVEDQKR 385
              + +++L GE+       E E +  K+  L   +  +     E +KR
Sbjct: 1056 LQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQL--LREEPEKR 1101



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 71/350 (20%), Positives = 142/350 (40%), Gaps = 39/350 (11%)

Query: 54   RRAAAERGAVELKKNEFQGELEKQREQ-LDKIQSSHNFQLESVNKLYQDEKAVLVNN-IT 111
            R     R   + K  E +  L+++ EQ L + +    F+ E +    Q  K +     + 
Sbjct: 1325 REEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLR 1384

Query: 112  TGERLIRVLQD--QLKTLQRNYGRLQQDVLQFQKNQTNL-----ERKFSYDLSQCINQMK 164
              ER  + L++  QL+  +R     Q    +F++ +  L     +RKF  +  Q   Q +
Sbjct: 1385 RQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQER 1444

Query: 165  EVK-----EQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTE 219
            E K     +Q  +      ++  + +  R+  + + Q +  + L E Q   +        
Sbjct: 1445 ERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRR-------- 1496

Query: 220  VPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQV 279
              Q +       + ++  P  +  L+ ++Q+ +++    + + EE Q  R  QE G+++ 
Sbjct: 1497 --QERDRKFREQELRSQEPERKF-LEEEQQLHRQQRQR-KFLQEEQQLRR--QERGQQRR 1550

Query: 280  VEDRPVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQE----EEQEA 335
             +DR    R F    +L Q  + Q    +S++  + +    +Q V    QE    E+++ 
Sbjct: 1551 -QDRD---RKFREEEQLRQEREEQ---QLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQ 1603

Query: 336  AGEGRNQQKLRGEDDYNMDENEAESETDKQAALAGNDRNIDVFNVEDQKR 385
                  QQ+LR E D    E+E   +  ++  L   +R+      E Q R
Sbjct: 1604 LRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLR 1653


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 43/201 (21%), Positives = 84/201 (41%), Gaps = 10/201 (4%)

Query: 176  EVTKKGNEAVASRDLSENNDQRQQLQAL-SEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQ 234
            EV  +   A A     E   + + ++AL +E +   ++ G    E  +      G ++ +
Sbjct: 1898 EVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPE 1957

Query: 235  TPA-PSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQE-----PGREQVVEDRPVGGR 288
            +    S E   +++ + E  E  E++V  +E + +  P+      P  E  +++     +
Sbjct: 1958 SEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQ 2017

Query: 289  GFGGAGELGQTPQVQAALSVSQENPEMEG---PERDQLVIPDGQEEEQEAAGEGRNQQKL 345
                  E     + + A  V  E  + EG   PE D +  P+ +EE QEA GE +  +  
Sbjct: 2018 PESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGE 2077

Query: 346  RGEDDYNMDENEAESETDKQA 366
               +  ++D  EAE E   ++
Sbjct: 2078 AHPESEDVDAQEAEGEAQPES 2098



 Score = 37.7 bits (86), Expect = 0.019
 Identities = 46/214 (21%), Positives = 79/214 (36%), Gaps = 23/214 (10%)

Query: 169  QCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVL 228
            + E+  E ++++G         S + D  Q   A    Q   Q+ G    E P+ +G   
Sbjct: 1789 EAEQEGEGISERGETGGQG---SGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQ 1845

Query: 229  GNSKSQTPAPSSE---VVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQVVEDRPV 285
              S+    AP +E      + + Q E E+    +   E        + P  E  V+    
Sbjct: 1846 PESEG-VEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESE 1904

Query: 286  GGRGFGGAGELG-QTPQVQAALSVSQENPEMEGPERDQLV---------------IPDGQ 329
            G        E   +T  V+A  +  ++ PE EG E  +                 + + Q
Sbjct: 1905 GAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQ 1964

Query: 330  EEEQEAAGEGRNQQKLRGEDDYNMDENEAESETD 363
            E E+EA  E  + + L  E +    E EA+ E++
Sbjct: 1965 EAEEEAQPESEDVEALEVEVETQEAEGEAQPESE 1998



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 41/205 (20%), Positives = 75/205 (36%), Gaps = 29/205 (14%)

Query: 168  EQCEERIEEVTKKGNEAVASRDLSEN-NDQRQQLQALSEPQPRLQAAGLPH-----TEVP 221
            E+  +  E  T+  +E + S++  E    + + ++AL       +A G         E P
Sbjct: 1944 EEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAP 2003

Query: 222  QGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQVVE 281
            + +G +      +   P S+ V +++ + E EE  E++   ++ + D  P+  G E    
Sbjct: 2004 EAEGEM--QEAEEEAQPESDGV-EAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEA 2060

Query: 282  DRPVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGEGRN 341
            +                    + A     E  E EG    +    D QE E EA  E   
Sbjct: 2061 E--------------------EEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEG 2100

Query: 342  QQKLRGEDDYNMDENEAESETDKQA 366
             +    E +    E     ET+ +A
Sbjct: 2101 VEAPEAEGEAQKAEGIEAPETEGEA 2125



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 46/206 (22%), Positives = 84/206 (40%), Gaps = 15/206 (7%)

Query: 165  EVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGK 224
            E +E+ +E   EV +   EA      SE+ D ++   A  E QP  +    P  E    K
Sbjct: 2059 EAEEEAQEAEGEVQEAEGEAHPE---SEDVDAQE---AEGEAQPESEGVEAPEAEGEAQK 2112

Query: 225  GNVLGNSKSQTPA-PSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGRE--QVVE 281
               +   +++  A P SE +   + + E +  +E  V  ++ + +  P+  G E  +  E
Sbjct: 2113 AEGIEAPETEGEAQPESEGIEAPEAEGEAQPESE-GVEAQDAEGEAQPESEGIEAQEAEE 2171

Query: 282  DRPVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGEGRN 341
            +      G       G+       +    E PE EG  + +L   +  E E+EA  E   
Sbjct: 2172 EAQPELEGVEAPEAEGEAQPESEGI----EAPEAEGEAQPELEGVEAPEAEEEAQPEPEG 2227

Query: 342  QQKLRGEDDYNMDENEAESETDKQAA 367
             +    E +    E+E E++ +K+ +
Sbjct: 2228 VETPEAEGE-AQPESEGETQGEKKGS 2252



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 42/182 (23%), Positives = 72/182 (39%), Gaps = 24/182 (13%)

Query: 191  SENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQV 250
            SE  +  Q+ + +SE +      G  H +  QG+    G+   Q P  S         + 
Sbjct: 1785 SELGEAEQEGEGISE-RGETGGQGSGHEDNLQGEAAAGGD---QDPGQSDGAEGIEAPEA 1840

Query: 251  EKEETNEIQVVNEEPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQTPQVQAALSVSQ 310
            E E   E + V E P+ +   QE   E   E   V            + P+ +       
Sbjct: 1841 EGEAQPESEGV-EAPEAEGDAQEAEGEAQPESEDV------------EAPEAEG--EAQP 1885

Query: 311  ENPEMEGPERDQLVIPDGQ-----EEEQEAAGEGRNQQKLRGEDDYNMDENEAESETDKQ 365
            E+ ++E PE +  V P+ +     E E+EA  E  + + L  E +   +   AE++  ++
Sbjct: 1886 ESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEE 1945

Query: 366  AA 367
            AA
Sbjct: 1946 AA 1947


>gi|70980531 GGA binding partner [Homo sapiens]
          Length = 441

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 63/294 (21%), Positives = 124/294 (42%), Gaps = 32/294 (10%)

Query: 107 VNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFSYDLSQCI----NQ 162
           V+NI   ++ I  L+ +LK  +    R++QDV    +    LE+ F  +  Q      ++
Sbjct: 129 VSNIQLQQK-ISSLEIKLKVSEEEKQRIKQDVESLMEKHNVLEKGFLKEKEQEAISFQDR 187

Query: 163 MKEVKEQCEERIEEVTKKGNEA----VASRDLSENNDQRQQLQALSEPQPRLQAAGLPHT 218
            KE++E+ ++ +E++ K G+EA    V        +  +QQ++A+ +         +   
Sbjct: 188 YKELQEKHKQELEDMRKAGHEALSIIVDEYKALLQSSVKQQVEAIEKQY-------ISAI 240

Query: 219 EVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGREQ 278
           E    K   L N++ Q        +LD+++++ KE+  E  +   + Q++ L      + 
Sbjct: 241 EKQAHKCEELLNAQHQRLLE----MLDTEKELLKEKIKEALIQQSQEQKEIL-----EKC 291

Query: 279 VVEDRPVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGE 338
           + E+R         A +L +     A L V +E       ER  L     +E E      
Sbjct: 292 LEEERQRNKEALVSAAKLEKEAVKDAVLKVVEE-------ERKNLEKAHAEERELWKTEH 344

Query: 339 GRNQQKLRGEDDYNMDENEAESETDKQAALAGNDRNIDVFNVEDQKRDTINLLD 392
            ++Q+K+  E    + E    S+   +AA+    +  +    E  KR    L++
Sbjct: 345 AKDQEKVSQEIQKAIQEQRKISQETVKAAIIEEQKRSEKAVEEAVKRTRDELIE 398


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 37/143 (25%), Positives = 69/143 (48%), Gaps = 25/143 (17%)

Query: 40   VDLQTRIMELEGRVRRAAAERGAVELKKNEFQGEL----------EKQREQLDKIQSSHN 89
            V L+ ++ +LEG + +    R  +E  K + +G+L          E  ++QLD+     +
Sbjct: 1025 VKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKD 1084

Query: 90   FQLESVNKLYQDEKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLE 149
            F+L ++N   +DE+A           L   LQ +LK LQ     L+++ L+ ++      
Sbjct: 1085 FELNALNARIEDEQA-----------LGSQLQKKLKELQARIEELEEE-LEAERTARAKV 1132

Query: 150  RKFSYDLSQCINQMKEVKEQCEE 172
             K   DLS+   +++E+ E+ EE
Sbjct: 1133 EKLRSDLSR---ELEEISERLEE 1152



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 81/403 (20%), Positives = 165/403 (40%), Gaps = 49/403 (12%)

Query: 41   DLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLE------- 93
            +LQ RI ELE  +      R  VE  +++   ELE+  E+L++   + + Q+E       
Sbjct: 1110 ELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREA 1169

Query: 94   SVNKLYQDEKAVLVNNITTGERL-------IRVLQDQLKTLQRNYGRLQQDVLQFQKN-- 144
               K+ +D +   + +  T   L       +  L +Q+  LQR   +L+++  +F+    
Sbjct: 1170 EFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELD 1229

Query: 145  --QTNLER--KFSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRD--LSENNDQRQ 198
               +N+E+  K   +L +    +++   +   + EE  +  N+  + R    +EN +  +
Sbjct: 1230 DVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSR 1289

Query: 199  QLQALSEPQPRLQAAGLPHTE-----VPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKE 253
            QL        +L    L +T+       Q +  V   +       S+    D  R+  +E
Sbjct: 1290 QLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE 1349

Query: 254  ETN---EIQVV----NEEPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQTPQVQAAL 306
            ET    E+Q V    N E  + R   E    Q  E+     +    A  L +  +   A+
Sbjct: 1350 ETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKL--AQRLQEAEEAVEAV 1407

Query: 307  -----SVSQENPEMEGPERDQLVIPDGQEEEQEAAG---EGRNQQKLRGEDDYNMDENEA 358
                 S+ +    ++    D +V  D +     AA    + RN  K+  E     +E+++
Sbjct: 1408 NAKCSSLEKTKHRLQNEIEDLMV--DVERSNAAAAALDKKQRNFDKILAEWKQKYEESQS 1465

Query: 359  ESETDKQAALAGNDRNIDVFNVEDQKRDTINLLDQREKRNHTL 401
            E E+ ++ A      + ++F +++   +++  L+  ++ N  L
Sbjct: 1466 ELESSQKEA---RSLSTELFKLKNAYEESLEHLETFKRENKNL 1505



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 66/377 (17%), Positives = 148/377 (39%), Gaps = 40/377 (10%)

Query: 42   LQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQLDKIQSSHNFQLESVNKLYQD 101
            L T + +L+     +       + +    Q E+    EQL     + + +LE V K  + 
Sbjct: 1477 LSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIH-ELEKVRKQLEA 1535

Query: 102  EKAVLVNNITTGERLIRVLQDQLKTLQRNYGRLQQDVLQFQKNQTNLERKFS---YDLSQ 158
            EK  L +           L++   +L+   G++ +  L+F + +  +ERK +    ++ Q
Sbjct: 1536 EKMELQS----------ALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQ 1585

Query: 159  CINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENNDQRQQLQ--------ALSEPQPRL 210
                   V +  +  ++  T+  NEA+  +   E +    ++Q        A ++ Q + 
Sbjct: 1586 AKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 1645

Query: 211  QAAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRL 270
              + L  T++           ++      +  +++ +  + + E  E++ V E+ +R R 
Sbjct: 1646 LQSLLKDTQIQLDDA-----VRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRK 1700

Query: 271  PQEPGREQVVEDRPVGGRGFGGAGELGQTPQVQAALSVSQENPE------MEGPERDQLV 324
              E  +E +     V          + Q  ++ A LS  Q   E          E+ +  
Sbjct: 1701 LAE--QELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKA 1758

Query: 325  IPDG---QEEEQEAAGEGRNQQKLRGEDDYNMDENEAESETDKQAALAGNDRNIDVFNVE 381
            I D     EE ++      + ++++   +  + + +   +  +Q AL G  + +    +E
Sbjct: 1759 ITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQ--KLE 1816

Query: 382  DQKRDTINLLDQREKRN 398
             + R+  N L+  +KRN
Sbjct: 1817 ARVRELENELEAEQKRN 1833



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 74/387 (19%), Positives = 154/387 (39%), Gaps = 78/387 (20%)

Query: 37   SRSVDLQTRIMELEGRVRRAAAERGAVELKKNEFQGELEKQREQ---------------L 81
            +  ++LQ+ + E E  +     +    +L+ N+ + E+E++  +               +
Sbjct: 1535 AEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVV 1594

Query: 82   DKIQSSHNFQLESVNKLYQDEKAV------LVNNITTGERLIRVLQDQLKTLQRNYGRLQ 135
            D +Q+S + +  S N+  + +K +      +   ++   R+    Q Q+K+L        
Sbjct: 1595 DSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSL-------- 1646

Query: 136  QDVLQFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIEEVTKKGNEAVASRDLSENND 195
            Q +L+  + Q +   + + DL + I  ++      +  +EE+     +   SR L+E   
Sbjct: 1647 QSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAE--- 1703

Query: 196  QRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSKRQVEKEET 255
                 Q L E   R+Q   L H++        L N K +  A  S++  +          
Sbjct: 1704 -----QELIETSERVQ---LLHSQ-----NTSLINQKKKMDADLSQLQTE---------- 1740

Query: 256  NEIQVVNEEPQRDRLPQEPGREQVVEDRPVGGRGFGGAGELGQTPQVQAALSVSQENPEM 315
                 V E  Q  R  +E  ++ + +   +       A EL +     A L   ++N  M
Sbjct: 1741 -----VEEAVQECRNAEEKAKKAITDAAMM-------AEELKKEQDTSAHLERMKKN--M 1786

Query: 316  EGPERDQLVIPDGQEEEQEAAGEGRNQQKLRGEDDYNMDENEAESETDKQA----ALAGN 371
            E   +D   +    +E ++ A +G  +Q  + E      ENE E+E  + A     +  +
Sbjct: 1787 EQTIKD---LQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKS 1843

Query: 372  DRNID--VFNVEDQKRDTINLLDQREK 396
            +R I    +  E+ +++ + L D  +K
Sbjct: 1844 ERRIKELTYQTEEDRKNLLRLQDLVDK 1870


>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
          Length = 282

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 52/243 (21%), Positives = 100/243 (41%), Gaps = 39/243 (16%)

Query: 119 VLQDQLKTLQRNYGRLQQDVL---QFQKNQTNLERKFSYDLSQCINQMKEVKEQCEERIE 175
           ++++ + T  +     +Q+ +    + +N  N E K    +++     KE+ E  EE IE
Sbjct: 51  MMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAK----ITEAPASEKEIVEVKEENIE 106

Query: 176 EVTKKG---NEAVASRDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSK 232
           + T+KG    EAVA+   +E  DQ++  +  +E +               GK +  GN K
Sbjct: 107 DATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEK 166

Query: 233 SQ----------------TPAPSSEVVLDSKRQVEKEETNEIQVVNEEPQRDRLPQEPGR 276
            +                      E   D K + +++ET + +    E  +++  ++ G+
Sbjct: 167 GEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGK--ENEDGKEKGDKKEGK 224

Query: 277 EQVV----EDRPVGGRGFGGAGELGQTPQVQAALSVSQENPEMEGPERDQLVIPDGQEEE 332
           +  V    ++R  G    GG  E       +A         E EG E D++   DG++EE
Sbjct: 225 DVKVKEDEKEREDGKEDEGGNEE-------EAGKEKEDLKEEEEGKEEDEIKEDDGKKEE 277

Query: 333 QEA 335
            ++
Sbjct: 278 PQS 280



 Score = 35.4 bits (80), Expect = 0.092
 Identities = 50/203 (24%), Positives = 80/203 (39%), Gaps = 22/203 (10%)

Query: 188 RDLSENNDQRQQLQALSEPQPRLQAAGLPHTEVPQGKGNVLGNSKSQTPAPSSEVVLDSK 247
           R  +   D RQ+ +  S    RL A  +P T   + K     + K +T +   E  +D+ 
Sbjct: 4   RKAAGQGDMRQEPKRRSA---RLSAMLVPVTPEVKPK-RTSSSRKMKTKSDMMEENIDTS 59

Query: 248 RQVEKEETNEIQVVNEEPQRD------RLPQEPGREQVVEDRPVGGRGFGGAGELGQTPQ 301
            Q   E T +  VV E+   +      ++ + P  E+ + +  V       A E G   +
Sbjct: 60  AQAVAE-TKQEAVVEEDYNENAKNGEAKITEAPASEKEIVE--VKEENIEDATEKGGEKK 116

Query: 302 VQAALSVSQENPEMEGPERDQLVIPDGQEEEQEAAGEGRNQQKLRGEDDYNMDENEAESE 361
              A  V  E  + +  E DQ       EE+ EA  E +++   +GE+D   D+N  E  
Sbjct: 117 EAVAAEVKNEEEDQKEDEEDQ------NEEKGEAGKEDKDE---KGEEDGKEDKNGNEKG 167

Query: 362 TDKQAALAGNDRNIDVFNVEDQK 384
            D +    G        N ED K
Sbjct: 168 EDAKEKEDGKKGEDGKGNGEDGK 190


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.128    0.347 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,168,368
Number of Sequences: 37866
Number of extensions: 760066
Number of successful extensions: 6345
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 641
Number of HSP's that attempted gapping in prelim test: 4584
Number of HSP's gapped (non-prelim): 1899
length of query: 401
length of database: 18,247,518
effective HSP length: 104
effective length of query: 297
effective length of database: 14,309,454
effective search space: 4249907838
effective search space used: 4249907838
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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