Guide to the Human Genome
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Search of human proteins with 122937209

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122937209 hypothetical protein LOC728858 [Homo sapiens]
         (269 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122937209 hypothetical protein LOC728858 [Homo sapiens]            554   e-158
gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens]         32   0.76 
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]         31   0.99 
gi|156104891 general transcription factor IIF, polypeptide 1, 74...    31   0.99 
gi|24308113 KIF1 binding protein [Homo sapiens]                        31   0.99 
gi|226423889 myocardin isoform 1 [Homo sapiens]                        30   1.7  
gi|23957692 myocardin isoform 2 [Homo sapiens]                         30   1.7  
gi|226423891 myocardin isoform 3 [Homo sapiens]                        30   1.7  
gi|111118961 sorting nexin 21 isoform d [Homo sapiens]                 30   2.2  
gi|15553099 sorting nexin 21 isoform a [Homo sapiens]                  30   2.2  
gi|111118959 sorting nexin 21 isoform c [Homo sapiens]                 30   2.2  
gi|23510350 sorting nexin 21 isoform b [Homo sapiens]                  30   2.2  
gi|195963418 tubulin tyrosine ligase-like family, member 6 isofo...    30   2.9  
gi|195963416 tubulin tyrosine ligase-like family, member 6 isofo...    30   2.9  
gi|208431781 cyclic nucleotide gated channel beta 1 isoform b [H...    29   3.8  
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H...    29   3.8  
gi|158534077 regulator of G-protein signaling 22 [Homo sapiens]        29   3.8  
gi|81295809 pericentrin [Homo sapiens]                                 29   4.9  
gi|66932918 MER receptor tyrosine kinase precursor [Homo sapiens]      29   4.9  
gi|38016947 complement component 5 preproprotein [Homo sapiens]        28   8.4  
gi|115495445 ankyrin repeat domain 30A [Homo sapiens]                  28   8.4  
gi|138175817 zinc finger protein 236 [Homo sapiens]                    28   8.4  

>gi|122937209 hypothetical protein LOC728858 [Homo sapiens]
          Length = 269

 Score =  554 bits (1428), Expect = e-158
 Identities = 269/269 (100%), Positives = 269/269 (100%)

Query: 1   MAYSSSNSDIEDDSSKSNSNLSLSVGYFPCEDTPCEDTTSWEDAPSKGPSIHFLPPVQGA 60
           MAYSSSNSDIEDDSSKSNSNLSLSVGYFPCEDTPCEDTTSWEDAPSKGPSIHFLPPVQGA
Sbjct: 1   MAYSSSNSDIEDDSSKSNSNLSLSVGYFPCEDTPCEDTTSWEDAPSKGPSIHFLPPVQGA 60

Query: 61  WGTERIGRRMKRQDQIQDEPEQFCKLSIFLAWDVDIGSDNTDSRANRLLNGDNLWIDKLP 120
           WGTERIGRRMKRQDQIQDEPEQFCKLSIFLAWDVDIGSDNTDSRANRLLNGDNLWIDKLP
Sbjct: 61  WGTERIGRRMKRQDQIQDEPEQFCKLSIFLAWDVDIGSDNTDSRANRLLNGDNLWIDKLP 120

Query: 121 KERTKLSVGKLNNLVQEFQIFLENLKDDDAVFPETAQQDFQLSSGSPPEMVQMISQATAS 180
           KERTKLSVGKLNNLVQEFQIFLENLKDDDAVFPETAQQDFQLSSGSPPEMVQMISQATAS
Sbjct: 121 KERTKLSVGKLNNLVQEFQIFLENLKDDDAVFPETAQQDFQLSSGSPPEMVQMISQATAS 180

Query: 181 QRTSAPEISSILSEQPEKDDTPSHTQAQCCLNFGWAFSWLRQRILPSLLRRDHPVNATKS 240
           QRTSAPEISSILSEQPEKDDTPSHTQAQCCLNFGWAFSWLRQRILPSLLRRDHPVNATKS
Sbjct: 181 QRTSAPEISSILSEQPEKDDTPSHTQAQCCLNFGWAFSWLRQRILPSLLRRDHPVNATKS 240

Query: 241 PHRSAPTKRLFHRGKRIQPQETLELGHPI 269
           PHRSAPTKRLFHRGKRIQPQETLELGHPI
Sbjct: 241 PHRSAPTKRLFHRGKRIQPQETLELGHPI 269


>gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens]
          Length = 1263

 Score = 31.6 bits (70), Expect = 0.76
 Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 4/54 (7%)

Query: 160 FQLSSGSPPEM----VQMISQATASQRTSAPEISSILSEQPEKDDTPSHTQAQC 209
           F+  S SPP M    +Q    A++SQ    P  S+I  +QPE   +P +    C
Sbjct: 684 FRQPSNSPPPMSSAMIQPHGAASSSQFQGLPSRSAIFQQQPENCSSPPNVALTC 737


>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
          Length = 2968

 Score = 31.2 bits (69), Expect = 0.99
 Identities = 19/55 (34%), Positives = 25/55 (45%)

Query: 4    SSSNSDIEDDSSKSNSNLSLSVGYFPCEDTPCEDTTSWEDAPSKGPSIHFLPPVQ 58
            SSS+S     SS S+S+ S S      ED+ C        AP+ GPS     P +
Sbjct: 2648 SSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTK 2702


>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
           [Homo sapiens]
          Length = 517

 Score = 31.2 bits (69), Expect = 0.99
 Identities = 38/158 (24%), Positives = 66/158 (41%), Gaps = 31/158 (19%)

Query: 68  RRMKRQDQIQDEPE-------QFCKLSIF-LAWDVDIGSDNTDSRANRLLNGDNLWIDKL 119
           RR+K QDQ +DE E       +  +L I  L  D+++ SD +D+              ++
Sbjct: 180 RRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEE--------GGRV 231

Query: 120 PKERTKLSVGKLNNLVQEFQIFLENLKDDDAVFPETAQQDFQ------LSSGSPPEMVQM 173
           PK + K  + K     +      +    DD  F ++   DF+      +S GS     + 
Sbjct: 232 PKAKKKAPLAKGGRKKK------KKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEP 285

Query: 174 ISQATASQRTSAP---EISSILSEQPEKDDTPSHTQAQ 208
            S+A A Q+   P   +  S  SE+ E++  P   + +
Sbjct: 286 ESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEE 323


>gi|24308113 KIF1 binding protein [Homo sapiens]
          Length = 621

 Score = 31.2 bits (69), Expect = 0.99
 Identities = 15/36 (41%), Positives = 25/36 (69%), Gaps = 4/36 (11%)

Query: 128 VGKLNNL----VQEFQIFLENLKDDDAVFPETAQQD 159
           V K+NNL    ++ +Q+FL++L+D + VFPE   +D
Sbjct: 503 VKKINNLNKSALKYYQLFLDSLRDPNKVFPEHIGED 538


>gi|226423889 myocardin isoform 1 [Homo sapiens]
          Length = 986

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 1/97 (1%)

Query: 108 LLNGDNLWIDKLPKERTKLSVGKLNNLVQEFQIFLENLKDDDAVFPETAQQDFQLSSGSP 167
           L+  + L +D   KE  K +    +     F  F E+   D     +T  +D Q S+GSP
Sbjct: 121 LVEKNILPVDSAVKEAIKGNQVSFSKSTDAFA-FEEDSSSDGLSPDQTRSEDPQNSAGSP 179

Query: 168 PEMVQMISQATASQRTSAPEISSILSEQPEKDDTPSH 204
           P+     + +T S  T+    S   +++ +    PSH
Sbjct: 180 PDAKASDTPSTGSLGTNQDLASGSENDRNDSASQPSH 216


>gi|23957692 myocardin isoform 2 [Homo sapiens]
          Length = 938

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 1/97 (1%)

Query: 108 LLNGDNLWIDKLPKERTKLSVGKLNNLVQEFQIFLENLKDDDAVFPETAQQDFQLSSGSP 167
           L+  + L +D   KE  K +    +     F  F E+   D     +T  +D Q S+GSP
Sbjct: 121 LVEKNILPVDSAVKEAIKGNQVSFSKSTDAFA-FEEDSSSDGLSPDQTRSEDPQNSAGSP 179

Query: 168 PEMVQMISQATASQRTSAPEISSILSEQPEKDDTPSH 204
           P+     + +T S  T+    S   +++ +    PSH
Sbjct: 180 PDAKASDTPSTGSLGTNQDLASGSENDRNDSASQPSH 216


>gi|226423891 myocardin isoform 3 [Homo sapiens]
          Length = 684

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 1/97 (1%)

Query: 108 LLNGDNLWIDKLPKERTKLSVGKLNNLVQEFQIFLENLKDDDAVFPETAQQDFQLSSGSP 167
           L+  + L +D   KE  K +    +     F  F E+   D     +T  +D Q S+GSP
Sbjct: 25  LVEKNILPVDSAVKEAIKGNQVSFSKSTDAFA-FEEDSSSDGLSPDQTRSEDPQNSAGSP 83

Query: 168 PEMVQMISQATASQRTSAPEISSILSEQPEKDDTPSH 204
           P+     + +T S  T+    S   +++ +    PSH
Sbjct: 84  PDAKASDTPSTGSLGTNQDLASGSENDRNDSASQPSH 120


>gi|111118961 sorting nexin 21 isoform d [Homo sapiens]
          Length = 158

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 18/75 (24%), Positives = 37/75 (49%), Gaps = 10/75 (13%)

Query: 7   NSDIEDDSSKS-NSNLSLSVGYFPCEDTPCEDTTSWEDAP---------SKGPSIHFLPP 56
           +S++EDD ++  +S LS ++ +   ED   ++    E+A          + G      PP
Sbjct: 42  SSELEDDDAEGLSSRLSGTLSFTSAEDDEDDEDEDDEEAGPDQLPLGDGTSGEDAERSPP 101

Query: 57  VQGAWGTERIGRRMK 71
             G WG++ + R+++
Sbjct: 102 PDGQWGSQLLARQLQ 116


>gi|15553099 sorting nexin 21 isoform a [Homo sapiens]
          Length = 373

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 18/75 (24%), Positives = 37/75 (49%), Gaps = 10/75 (13%)

Query: 7   NSDIEDDSSKS-NSNLSLSVGYFPCEDTPCEDTTSWEDAP---------SKGPSIHFLPP 56
           +S++EDD ++  +S LS ++ +   ED   ++    E+A          + G      PP
Sbjct: 42  SSELEDDDAEGLSSRLSGTLSFTSAEDDEDDEDEDDEEAGPDQLPLGDGTSGEDAERSPP 101

Query: 57  VQGAWGTERIGRRMK 71
             G WG++ + R+++
Sbjct: 102 PDGQWGSQLLARQLQ 116


>gi|111118959 sorting nexin 21 isoform c [Homo sapiens]
          Length = 152

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 18/75 (24%), Positives = 37/75 (49%), Gaps = 10/75 (13%)

Query: 7   NSDIEDDSSKS-NSNLSLSVGYFPCEDTPCEDTTSWEDAP---------SKGPSIHFLPP 56
           +S++EDD ++  +S LS ++ +   ED   ++    E+A          + G      PP
Sbjct: 42  SSELEDDDAEGLSSRLSGTLSFTSAEDDEDDEDEDDEEAGPDQLPLGDGTSGEDAERSPP 101

Query: 57  VQGAWGTERIGRRMK 71
             G WG++ + R+++
Sbjct: 102 PDGQWGSQLLARQLQ 116


>gi|23510350 sorting nexin 21 isoform b [Homo sapiens]
          Length = 199

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 18/75 (24%), Positives = 37/75 (49%), Gaps = 10/75 (13%)

Query: 7   NSDIEDDSSKS-NSNLSLSVGYFPCEDTPCEDTTSWEDAP---------SKGPSIHFLPP 56
           +S++EDD ++  +S LS ++ +   ED   ++    E+A          + G      PP
Sbjct: 42  SSELEDDDAEGLSSRLSGTLSFTSAEDDEDDEDEDDEEAGPDQLPLGDGTSGEDAERSPP 101

Query: 57  VQGAWGTERIGRRMK 71
             G WG++ + R+++
Sbjct: 102 PDGQWGSQLLARQLQ 116


>gi|195963418 tubulin tyrosine ligase-like family, member 6 isoform
           1 [Homo sapiens]
          Length = 891

 Score = 29.6 bits (65), Expect = 2.9
 Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 7/62 (11%)

Query: 153 PETAQQDFQLSSGSPPEMVQMISQATASQRTSAPEISSILSEQPEKDDTPSH-TQAQCCL 211
           PE+  Q   +S  SPP +       TAS   S PE   ++S + +K  TP H TQ +   
Sbjct: 689 PESTTQ-LSISPKSPPTLA-----VTASSEYSGPETDRVVSFKCKKQQTPPHLTQKKMLK 742

Query: 212 NF 213
           +F
Sbjct: 743 SF 744


>gi|195963416 tubulin tyrosine ligase-like family, member 6 isoform
           2 [Homo sapiens]
          Length = 584

 Score = 29.6 bits (65), Expect = 2.9
 Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 7/62 (11%)

Query: 153 PETAQQDFQLSSGSPPEMVQMISQATASQRTSAPEISSILSEQPEKDDTPSH-TQAQCCL 211
           PE+  Q   +S  SPP +       TAS   S PE   ++S + +K  TP H TQ +   
Sbjct: 382 PESTTQ-LSISPKSPPTLA-----VTASSEYSGPETDRVVSFKCKKQQTPPHLTQKKMLK 435

Query: 212 NF 213
           +F
Sbjct: 436 SF 437


>gi|208431781 cyclic nucleotide gated channel beta 1 isoform b [Homo
           sapiens]
          Length = 299

 Score = 29.3 bits (64), Expect = 3.8
 Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 8/59 (13%)

Query: 219 WLRQ---RILP-----SLLRRDHPVNATKSPHRSAPTKRLFHRGKRIQPQETLELGHPI 269
           WL Q   R+LP     S + RD P  AT +    AP  R    G ++Q +ET  L  PI
Sbjct: 161 WLEQNLERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPI 219


>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
           sapiens]
          Length = 1251

 Score = 29.3 bits (64), Expect = 3.8
 Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 8/59 (13%)

Query: 219 WLRQ---RILP-----SLLRRDHPVNATKSPHRSAPTKRLFHRGKRIQPQETLELGHPI 269
           WL Q   R+LP     S + RD P  AT +    AP  R    G ++Q +ET  L  PI
Sbjct: 161 WLEQNLERVLPQPPKSSEVWRDEPAVATGAASDPAPPGRPQEMGPKLQARETPSLPTPI 219


>gi|158534077 regulator of G-protein signaling 22 [Homo sapiens]
          Length = 1264

 Score = 29.3 bits (64), Expect = 3.8
 Identities = 21/109 (19%), Positives = 45/109 (41%), Gaps = 10/109 (9%)

Query: 134 LVQEFQIFLENLKDDDAVFPETAQQDFQLSSGSPPEMVQMISQATASQRTSAP------- 186
           LV  F  FL      +A+        F++++ +P  + + + +   +Q+   P       
Sbjct: 28  LVDYFNEFLSLPTFSEAIRFNADYGVFEVANDAPQFLEKQLKKILQNQQPRNPIYDVVRK 87

Query: 187 ---EISSILSEQPEKDDTPSHTQAQCCLNFGWAFSWLRQRILPSLLRRD 232
              E+  +    P++D+T +      CL+      W+++  LP+ L  D
Sbjct: 88  GKNEVKPVQMNAPDEDETINVNYNIMCLSREEGIKWIKKERLPAFLESD 136


>gi|81295809 pericentrin [Homo sapiens]
          Length = 3336

 Score = 28.9 bits (63), Expect = 4.9
 Identities = 18/81 (22%), Positives = 35/81 (43%), Gaps = 7/81 (8%)

Query: 4   SSSNSDIEDDSSKSNSNLSLSVGYFPCEDTPCEDTTSWEDAPSKGPSIHFLPPVQGAWGT 63
           S+ ++ ++++S  +  + +L  G   C+ T C+DT         G    F    +   G 
Sbjct: 44  SAVDASVQEESPVTKEDSALCGGGDICKSTSCDDTPD-------GAGGAFAAQPEDCDGE 96

Query: 64  ERIGRRMKRQDQIQDEPEQFC 84
           +R      +Q Q+ D P + C
Sbjct: 97  KREDLEQLQQKQVNDHPPEQC 117


>gi|66932918 MER receptor tyrosine kinase precursor [Homo sapiens]
          Length = 999

 Score = 28.9 bits (63), Expect = 4.9
 Identities = 17/71 (23%), Positives = 34/71 (47%)

Query: 122 ERTKLSVGKLNNLVQEFQIFLENLKDDDAVFPETAQQDFQLSSGSPPEMVQMISQATASQ 181
           +R  L +GK+    +   +   NLK +D    + A +  +L + S  E+ + +S+A   +
Sbjct: 583 DRNLLILGKILGEGEFGSVMEGNLKQEDGTSLKVAVKTMKLDNSSQREIEEFLSEAACMK 642

Query: 182 RTSAPEISSIL 192
             S P +  +L
Sbjct: 643 DFSHPNVIRLL 653


>gi|38016947 complement component 5 preproprotein [Homo sapiens]
          Length = 1676

 Score = 28.1 bits (61), Expect = 8.4
 Identities = 19/63 (30%), Positives = 30/63 (47%), Gaps = 13/63 (20%)

Query: 132 NNLVQEFQIFL-----ENLKDDDAVFPETAQQDFQLSSGSPPEMVQMISQATASQRTSAP 186
           N +V E  +++     E+LKDD     +TA Q+  L +G        I+Q T    T+  
Sbjct: 257 NKVVTEADVYITFGIREDLKDDQKEMMQTAMQNTMLING--------IAQVTFDSETAVK 308

Query: 187 EIS 189
           E+S
Sbjct: 309 ELS 311


>gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
          Length = 1341

 Score = 28.1 bits (61), Expect = 8.4
 Identities = 16/62 (25%), Positives = 30/62 (48%), Gaps = 5/62 (8%)

Query: 143 ENLKDDDAVFPETAQQDFQLSSGSPPEMVQMISQ-----ATASQRTSAPEISSILSEQPE 197
           + L+ D    PE+ Q+D++ +S     + + +SQ       A+ +    +I+  L E P 
Sbjct: 488 QTLRADPMFPPESKQKDYEENSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPN 547

Query: 198 KD 199
           KD
Sbjct: 548 KD 549


>gi|138175817 zinc finger protein 236 [Homo sapiens]
          Length = 1845

 Score = 28.1 bits (61), Expect = 8.4
 Identities = 17/65 (26%), Positives = 24/65 (36%), Gaps = 2/65 (3%)

Query: 146  KDDDAVFPETAQQDFQLSSGSPPEMVQMISQATASQRTSAPEISSILSEQPEKDDTPSHT 205
            K    V   T ++  QL+   P E   +  +           IS +  +Q E  D P H 
Sbjct: 1107 KSRPEVITFTEEETAQLAKIRPQESATVSEKVLVQSAAEKDRISELRDKQAELQDEPKH- 1165

Query: 206  QAQCC 210
             A CC
Sbjct: 1166 -ANCC 1169


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,198,433
Number of Sequences: 37866
Number of extensions: 505086
Number of successful extensions: 1298
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1283
Number of HSP's gapped (non-prelim): 31
length of query: 269
length of database: 18,247,518
effective HSP length: 101
effective length of query: 168
effective length of database: 14,423,052
effective search space: 2423072736
effective search space used: 2423072736
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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