Search of human proteins with 12232385

Search of human proteins with 12232385

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|12232385 COP9 constitutive photomorphogenic homolog subunit
7B [Homo sapiens]
         (264 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|12232385 COP9 constitutive photomorphogenic homolog subunit 7...   515   e-146
gi|7705330 COP9 complex subunit 7a [Homo sapiens]                     301   3e-82
gi|23397429 eukaryotic translation initiation factor 3, subunit ...    46   4e-05
gi|61742825 disrupted in schizophrenia 1 isoform Lv [Homo sapiens]     34   0.15 
gi|61742823 disrupted in schizophrenia 1 isoform L [Homo sapiens]      34   0.15 
gi|81295809 pericentrin [Homo sapiens]                                 34   0.15 
gi|219842262 COP9 constitutive photomorphogenic homolog subunit ...    33   0.20 
gi|4759264 COP9 constitutive photomorphogenic homolog subunit 2 ...    33   0.20 
gi|22749049 Leber congenital amaurosis 5-like [Homo sapiens]           33   0.33 
gi|110611218 ribosome binding protein 1 [Homo sapiens]                 32   0.57 
gi|110611220 ribosome binding protein 1 [Homo sapiens]                 32   0.57 
gi|194018511 keratin 77 [Homo sapiens]                                 32   0.74 
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    32   0.74 
gi|7706637 protein inhibitor of activated STAT, 1 [Homo sapiens]       31   1.3  
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             31   1.3  
gi|24308223 hypothetical protein LOC57577 [Homo sapiens]               31   1.3  
gi|51100978 tweety 3 [Homo sapiens]                                    30   1.7  
gi|62912476 lethal giant larvae homolog 1 [Homo sapiens]               30   2.2  
gi|148277037 AP2 associated kinase 1 [Homo sapiens]                    30   2.2  
gi|110815815 centlein isoform 1 [Homo sapiens]                         30   2.2  
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H...    30   2.8  
gi|212549782 caspase 8 associated protein 2 [Homo sapiens]             30   2.8  
gi|6912288 caspase 8 associated protein 2 [Homo sapiens]               30   2.8  
gi|212549532 caspase 8 associated protein 2 [Homo sapiens]             30   2.8  
gi|55770834 centromere protein F [Homo sapiens]                        30   2.8  
gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens]           30   2.8  
gi|7662280 histone deacetylase 9 isoform 3 [Homo sapiens]              30   2.8  
gi|17158041 histone deacetylase 9 isoform 2 [Homo sapiens]             30   2.8  
gi|17158039 histone deacetylase 9 isoform 1 [Homo sapiens]             30   2.8  
gi|30795202 histone deacetylase 9 isoform 4 [Homo sapiens]             30   2.8  

>gi|12232385 COP9 constitutive photomorphogenic homolog subunit 7B
           [Homo sapiens]
          Length = 264

 Score =  515 bits (1327), Expect = e-146
 Identities = 264/264 (100%), Positives = 264/264 (100%)

Query: 1   MAGEQKPSSNLLEQFILLAKGTSGSALTALISQVLEAPGVYVFGELLELANVQELAEGAN 60
           MAGEQKPSSNLLEQFILLAKGTSGSALTALISQVLEAPGVYVFGELLELANVQELAEGAN
Sbjct: 1   MAGEQKPSSNLLEQFILLAKGTSGSALTALISQVLEAPGVYVFGELLELANVQELAEGAN 60

Query: 61  AAYLQLLNLFAYGTYPDYIANKESLPELSTAQQNKLKHLTIVSLASRMKCIPYSVLLKDL 120
           AAYLQLLNLFAYGTYPDYIANKESLPELSTAQQNKLKHLTIVSLASRMKCIPYSVLLKDL
Sbjct: 61  AAYLQLLNLFAYGTYPDYIANKESLPELSTAQQNKLKHLTIVSLASRMKCIPYSVLLKDL 120

Query: 121 EMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDG 180
           EMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDG
Sbjct: 121 EMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDG 180

Query: 181 CEAVLLGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAEREC 240
           CEAVLLGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAEREC
Sbjct: 181 CEAVLLGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAEREC 240

Query: 241 PPHAEQRQPTKKMSKVKGLVSSRH 264
           PPHAEQRQPTKKMSKVKGLVSSRH
Sbjct: 241 PPHAEQRQPTKKMSKVKGLVSSRH 264


>gi|7705330 COP9 complex subunit 7a [Homo sapiens]
          Length = 275

 Score =  301 bits (772), Expect = 3e-82
 Identities = 154/267 (57%), Positives = 204/267 (76%), Gaps = 5/267 (1%)

Query: 1   MAGEQKPSSNLLEQFILLAKGTSGSALTALISQVLEAPGVYVFGELLELANVQELAEGAN 60
           M+ E K +    EQF+LLAK   G+AL  LI QVLEAPGVYVFGELL++ NV+ELAE   
Sbjct: 1   MSAEVKVTGQNQEQFLLLAKSAKGAALATLIHQVLEAPGVYVFGELLDMPNVRELAESDF 60

Query: 61  AAYLQLLNLFAYGTYPDYIANKESLPELSTAQQNKLKHLTIVSLASRMKCIPYSVLLKDL 120
           A+  +LL +FAYGTY DY+A   +LP L+ AQ+NKL+HL++V+LA+++KCIPY+VLL+ L
Sbjct: 61  ASTFRLLTVFAYGTYADYLAEARNLPPLTEAQKNKLRHLSVVTLAAKVKCIPYAVLLEAL 120

Query: 121 EMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDG 180
            +RN+R+LEDL+IEAVY D+++G LDQRNQ LEVD+ IGRDI+++D++ I +TL EWC G
Sbjct: 121 ALRNVRQLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIARTLQEWCVG 180

Query: 181 CEAVLLGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKAT----ASSSAQEMEQQLA 236
           CE VL GIE+QV RANQ+KE     +QQ+E+EV N+KKT+K T    A++++Q+ EQ L 
Sbjct: 181 CEVVLSGIEEQVSRANQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQDPEQHLT 240

Query: 237 E-RECPPHAEQRQPTKKMSKVKGLVSS 262
           E RE  P   QRQP+KK SK KGL  S
Sbjct: 241 ELREPAPGTNQRQPSKKASKGKGLRGS 267


>gi|23397429 eukaryotic translation initiation factor 3, subunit M
           [Homo sapiens]
          Length = 374

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 39/154 (25%), Positives = 71/154 (46%), Gaps = 11/154 (7%)

Query: 31  ISQVLEAPGVYVFGELLELANVQELAEGANAAYLQLLNLFAYGTYPDYIA----NKESLP 86
           I + L+ P  ++F  LL L  V+ L EG       LL +F       Y+     NK+ + 
Sbjct: 208 IVRALKDPNAFLFDHLLTLKPVKFL-EGE--LIHDLLTIFVSAKLASYVKFYQNNKDFID 264

Query: 87  ELSTAQQN---KLKHLTIVSLASRMKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQG 143
            L    +    K++ LT + +A   K I +  + ++L++    ++E  +I+AV T ++  
Sbjct: 265 SLGLLHEQNMAKMRLLTFMGMAVENKEISFDTMQQELQI-GADDVEAFVIDAVRTKMVYC 323

Query: 144 KLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEW 177
           K+DQ  + + V     R   K+    +  TL+ W
Sbjct: 324 KIDQTQRKVVVSHSTHRTFGKQQWQQLYDTLNAW 357


>gi|61742825 disrupted in schizophrenia 1 isoform Lv [Homo sapiens]
          Length = 832

 Score = 33.9 bits (76), Expect = 0.15
 Identities = 18/81 (22%), Positives = 41/81 (50%), Gaps = 4/81 (4%)

Query: 165 KDINNIVKTLHEWCDGCEAVLLGI----EQQVLRANQYKENHNRTQQQVEAEVTNIKKTL 220
           KD+   +++L    +G E +L  +     + V +    KE++NR +++VE + T  + ++
Sbjct: 605 KDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSV 664

Query: 221 KATASSSAQEMEQQLAERECP 241
           K       + ++ +L   +CP
Sbjct: 665 KENTMKYMETLKNKLCSCKCP 685


>gi|61742823 disrupted in schizophrenia 1 isoform L [Homo sapiens]
          Length = 854

 Score = 33.9 bits (76), Expect = 0.15
 Identities = 18/81 (22%), Positives = 41/81 (50%), Gaps = 4/81 (4%)

Query: 165 KDINNIVKTLHEWCDGCEAVLLGI----EQQVLRANQYKENHNRTQQQVEAEVTNIKKTL 220
           KD+   +++L    +G E +L  +     + V +    KE++NR +++VE + T  + ++
Sbjct: 605 KDLTEEIRSLTSEREGLEGLLSKLLVLSSRNVKKLGSVKEDYNRLRREVEHQETAYETSV 664

Query: 221 KATASSSAQEMEQQLAERECP 241
           K       + ++ +L   +CP
Sbjct: 665 KENTMKYMETLKNKLCSCKCP 685


>gi|81295809 pericentrin [Homo sapiens]
          Length = 3336

 Score = 33.9 bits (76), Expect = 0.15
 Identities = 44/174 (25%), Positives = 73/174 (41%), Gaps = 20/174 (11%)

Query: 84   SLPELSTAQQNKLKHLTIVSLASRMKCI------PYSVLLKDLEMRNLRELEDLIIEAV- 136
            +L    TA+ N  K L I    SR + +        S L KDL     R LE  + EA+ 
Sbjct: 2707 ALKHEQTAKDNLQKELRIEH--SRCEALLAQERSQLSELQKDLAAEKSRTLE--LSEALR 2762

Query: 137  YTDIIQGKLDQRNQLLEVDFCIGRDIRKKD-INNIVKTLHEWCDGCEAVLLGIEQQVLRA 195
            +  ++  +L QR Q    + C+ +D +    +   +K         +A+L  ++QQ L +
Sbjct: 2763 HERLLTEQLSQRTQ----EACVHQDTQAHHALLQKLKEEKSRVVDLQAMLEKVQQQALHS 2818

Query: 196  NQYKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAERECPPHAEQRQP 249
             Q  E     + Q   E    +K + AT  S+ + +  Q  E  C    E+ +P
Sbjct: 2819 QQQLE----AEAQKHCEALRREKEVSATLKSTVEALHTQKRELRCSLEREREKP 2868


>gi|219842262 COP9 constitutive photomorphogenic homolog subunit 2
           isoform 2 [Homo sapiens]
          Length = 450

 Score = 33.5 bits (75), Expect = 0.20
 Identities = 16/45 (35%), Positives = 32/45 (71%), Gaps = 3/45 (6%)

Query: 111 IPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVD 155
           IP+  + K+L + ++ ++E L+++ +  + I G++DQ NQLLE+D
Sbjct: 378 IPF--ISKELNI-DVADVESLLVQCILDNTIHGRIDQVNQLLELD 419


>gi|4759264 COP9 constitutive photomorphogenic homolog subunit 2
           isoform 1 [Homo sapiens]
          Length = 443

 Score = 33.5 bits (75), Expect = 0.20
 Identities = 16/45 (35%), Positives = 32/45 (71%), Gaps = 3/45 (6%)

Query: 111 IPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVD 155
           IP+  + K+L + ++ ++E L+++ +  + I G++DQ NQLLE+D
Sbjct: 371 IPF--ISKELNI-DVADVESLLVQCILDNTIHGRIDQVNQLLELD 412


>gi|22749049 Leber congenital amaurosis 5-like [Homo sapiens]
          Length = 670

 Score = 32.7 bits (73), Expect = 0.33
 Identities = 50/218 (22%), Positives = 94/218 (43%), Gaps = 34/218 (15%)

Query: 29  ALISQVLEAPGVYVFGELLELANVQE-----LAEGANAAYLQLLNLFAYGTYPDYIANKE 83
           A+  ++L A    + G   ELA++       L E      LQL +L A G Y +   ++ 
Sbjct: 138 AMAHRILSARLHKIKGLKNELADMHHKLEAILTENQFLKQLQLRHLKAIGKYEN---SQN 194

Query: 84  SLPELSTAQQNKLKHLTIVSLASRMKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQG 143
           +LP++    QN++K+L  +   S+ K    S        R LRE +  +++    DI+Q 
Sbjct: 195 NLPQIMAKHQNEVKNLRQLLRKSQEKERTLS--------RKLRETDSQLLKT--KDILQA 244

Query: 144 --KLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLLGIEQQVLRANQYKEN 201
             KL +   L E          ++++ + +  +    D  +  +  +E+Q LR N    +
Sbjct: 245 LQKLSEDKNLAE----------REELTHKLSIITTKMDANDKKIQSLEKQ-LRLNCRAFS 293

Query: 202 HNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAERE 239
               Q  +E   T   +T   T     + ++Q+L E++
Sbjct: 294 R---QLAIETRKTLAAQTATKTLQVEVKHLQQKLKEKD 328


>gi|110611218 ribosome binding protein 1 [Homo sapiens]
          Length = 977

 Score = 32.0 bits (71), Expect = 0.57
 Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 12/87 (13%)

Query: 182 EAVLLGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASS---------SAQEME 232
           EA     E+QVL   Q + +H  +++ ++  +  + + L  T SS          AQE +
Sbjct: 423 EAKAAAFEKQVL---QLQASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQ 479

Query: 233 QQLAERECPPHAEQRQPTKKMSKVKGL 259
           QQ+AE      + + +   K  ++ GL
Sbjct: 480 QQMAELHSKLQSSEAEVRSKCEELSGL 506


>gi|110611220 ribosome binding protein 1 [Homo sapiens]
          Length = 977

 Score = 32.0 bits (71), Expect = 0.57
 Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 12/87 (13%)

Query: 182 EAVLLGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASS---------SAQEME 232
           EA     E+QVL   Q + +H  +++ ++  +  + + L  T SS          AQE +
Sbjct: 423 EAKAAAFEKQVL---QLQASHRESEEALQKRLDEVSRELCHTQSSHASLRADAEKAQEQQ 479

Query: 233 QQLAERECPPHAEQRQPTKKMSKVKGL 259
           QQ+AE      + + +   K  ++ GL
Sbjct: 480 QQMAELHSKLQSSEAEVRSKCEELSGL 506


>gi|194018511 keratin 77 [Homo sapiens]
          Length = 578

 Score = 31.6 bits (70), Expect = 0.74
 Identities = 52/211 (24%), Positives = 86/211 (40%), Gaps = 54/211 (25%)

Query: 48  ELANVQELAEGANAAYLQLLNLFAYGTYPDYIANK-------------ESLPELSTAQQN 94
           E+ ++Q++ E   + Y   +N    G+  D++  K             ES  +  T + N
Sbjct: 239 EVRSMQDVVEDYKSKYEDEINKRT-GSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVN 297

Query: 95  KLKHLTIVSLASRMKCIPYSVLLKDLEMRNLRELE-DLIIEAVYTD---IIQGKLDQRNQ 150
            LK+L +  L+     I  + ++  L M N R L+ D II+AV T    I Q   D+   
Sbjct: 298 FLKYLFLTELSQVQTHISDTNVI--LSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEA 355

Query: 151 LL-----EVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLLGIEQQVLRANQYKENHNRT 205
           L      E+    GR     D+ N    + E                          NRT
Sbjct: 356 LYQTKYQELQITAGR--HGDDLKNSKMEIAEL-------------------------NRT 388

Query: 206 QQQVEAEVTNIKKTLKATAS--SSAQEMEQQ 234
            Q+++AE++N+KK ++   S  S A+E  +Q
Sbjct: 389 VQRLQAEISNVKKQIEQMQSLISDAEERGEQ 419


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 31.6 bits (70), Expect = 0.74
 Identities = 36/144 (25%), Positives = 65/144 (45%), Gaps = 16/144 (11%)

Query: 106  SRMKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKK 165
            S+ K +  +VL  +  ++++RE  + ++E V    ++ K+DQ    L+ D+        +
Sbjct: 3842 SKYKSLQQTVLSHEPSVKSVREKGEALLELVQDVTLKDKIDQ----LQSDY--------Q 3889

Query: 166  DINNIVKTLHEWCDGCEAVL--LGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKAT 223
            D+ +I K + E   G E  L  L ++   L          + +Q V A +   K +  A 
Sbjct: 3890 DLCSIGKAMMEEIAGFEDRLNNLQMKGDTLIGQCADHLQAKLKQNVHAHLQGTKDSYSAI 3949

Query: 224  ASSSAQEMEQQLAERECPPHAEQR 247
              S+AQ M Q L E E   H  ++
Sbjct: 3950 C-STAQRMYQSL-EHELQKHVSRQ 3971


>gi|7706637 protein inhibitor of activated STAT, 1 [Homo sapiens]
          Length = 651

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 33/136 (24%), Positives = 58/136 (42%), Gaps = 19/136 (13%)

Query: 129 EDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLLGI 188
           E LII+ ++ +I++   D      + D        KK++   V   +   DGC +  L  
Sbjct: 384 EHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMRSKKEVQE-VSASYNGVDGCLSSTL-- 440

Query: 189 EQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAERECPPHAEQRQ 248
                  +Q   +H  + +  + EV ++        SSS +E E+  A+R CP       
Sbjct: 441 ------EHQVASHHQSSNKNKKVEVIDL-----TIDSSSDEEEEEPSAKRTCP----SLS 485

Query: 249 PTKKMSKVKGLVSSRH 264
           PT  ++  KG++S  H
Sbjct: 486 PTSPLNN-KGILSLPH 500


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 42/184 (22%), Positives = 80/184 (43%), Gaps = 24/184 (13%)

Query: 84   SLPELSTAQQNKLKHLTIVSLASRMKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQG 143
            ++ EL  + + K K +  +    ++  +  + L   L+ +  +  ++L  E     ++Q 
Sbjct: 960  NINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQN 1019

Query: 144  KLDQRNQL---LEVDFCIGRDIRKKDINNIVKTLHEWCDGCEAVLLGIEQQVLRANQYK- 199
              ++  +    L+ DF  GR+         +K++ E         L + Q+ L +N+ + 
Sbjct: 1020 NYEKSQETFKQLQSDF-YGRESELLATRQDLKSVEE--------KLSLAQEDLISNRNQI 1070

Query: 200  ENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAERECPPHAEQRQPTKKMSKVKGL 259
             N N+  Q++        KT KAT    + + EQQL ER C   A Q    +K  K K L
Sbjct: 1071 GNQNKLIQEL--------KTAKATLEQDSAKKEQQLQER-C--KALQDIQKEKSLKEKEL 1119

Query: 260  VSSR 263
            V+ +
Sbjct: 1120 VNEK 1123


>gi|24308223 hypothetical protein LOC57577 [Homo sapiens]
          Length = 936

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 22/72 (30%), Positives = 39/72 (54%), Gaps = 3/72 (4%)

Query: 193 LRANQYKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAEREC-PPHAEQRQPTK 251
           +R  Q KEN  R +++ E E   I+KTLK +A   AQ + Q+  +R+      E+ +  +
Sbjct: 194 MRHKQVKEN--RLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQR 251

Query: 252 KMSKVKGLVSSR 263
           +M K++  +  R
Sbjct: 252 EMVKLRREIIER 263


>gi|51100978 tweety 3 [Homo sapiens]
          Length = 523

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 21/54 (38%), Positives = 26/54 (48%)

Query: 194 RANQYKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAERECPPHAEQR 247
           RA     + NRT   V+  V +    L  TA  S Q +E+QLA R  P  A QR
Sbjct: 117 RATYSLRHANRTVAGVQDRVWDTAVGLNHTAEPSLQTLERQLAGRPEPLRAVQR 170


>gi|62912476 lethal giant larvae homolog 1 [Homo sapiens]
          Length = 1064

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 186 LGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAERECPPHAE 245
           L +E  + R    K++  ++ +++     + KK   A ASS  QE   QLAE+ CP   E
Sbjct: 644 LAMEGPLSRVKSLKKSLRQSFRRIRKSRVSGKKRA-ANASSKLQEANAQLAEQACPHDVE 702


>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
          Length = 961

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 21/63 (33%), Positives = 30/63 (47%), Gaps = 8/63 (12%)

Query: 187 GIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQLAERECPPHAEQ 246
           G  QQ L  N Y++   + QQQ + ++        ATA    Q M QQ A ++ P  A  
Sbjct: 521 GGSQQQLMQNFYQQQQQQQQQQQQQQL--------ATALHQQQLMTQQAALQQKPTMAAG 572

Query: 247 RQP 249
           +QP
Sbjct: 573 QQP 575


>gi|110815815 centlein isoform 1 [Homo sapiens]
          Length = 1406

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 36/158 (22%), Positives = 75/158 (47%), Gaps = 21/158 (13%)

Query: 93   QNKLKHLT--IVSLASRMKCIPYSVLLKDLEMRNLRELEDLIIEAVYTDIIQGK--LDQR 148
            Q KLK+ T  +   +S +K + + +L K+  ++ + E     I  +  DI   +  ++  
Sbjct: 1098 QYKLKNATNELTKQSSNVKTLKFELLAKEEHIKEMHEK----ISRMERDITMKRHLIEDL 1153

Query: 149  NQLLEVDFCIGRDIRK--KDINNIVKTLHEWCDGCEAVLLGIEQQ----VLRANQYKENH 202
                +V+    +   +  ++++  VKTL E C   +  +  ++Q+    V   +QY++ +
Sbjct: 1154 KFRQKVNLESNKSFSEMLQNLDKKVKTLTEECSNKKVSIDSLKQRLNVAVKEKSQYEQMY 1213

Query: 203  NRTQQQVEAEVTNIKKTLKAT-ASSSAQEMEQQLAERE 239
             ++++++E      KK LK T   S   E E  +AE E
Sbjct: 1214 QKSKEELE------KKDLKLTLLVSRISETESAMAEIE 1245


>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
            sapiens]
          Length = 4515

 Score = 29.6 bits (65), Expect = 2.8
 Identities = 24/104 (23%), Positives = 51/104 (49%), Gaps = 5/104 (4%)

Query: 128  LEDLIIEAVYTDIIQGKLDQRNQLLE---VDFCIGRDIRKKDINNIVKTLHEWCDGCEAV 184
            L+D ++  V T  +    DQR++LLE   +D     ++ +K +N + K L    D  + +
Sbjct: 3417 LQDQLLSTVVTHEVPHLEDQRSKLLESISLDAITLEELEEKTLNLLQKALGSILDD-DKI 3475

Query: 185  LLGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSSA 228
            +  + +  + +N+  +    T ++ E+E+  I+K     A+  A
Sbjct: 3476 VDTLRKSKMTSNEISKRIEAT-KKAESEIQAIRKNYLPIATRGA 3518


>gi|212549782 caspase 8 associated protein 2 [Homo sapiens]
          Length = 1982

 Score = 29.6 bits (65), Expect = 2.8
 Identities = 17/66 (25%), Positives = 33/66 (50%), Gaps = 2/66 (3%)

Query: 194  RANQYKENHNRTQQQVEAEVTNIKKTLKATASS--SAQEMEQQLAERECPPHAEQRQPTK 251
            R N    NH   +Q+ E ++TN +KT K T  S  + +  +++ ++++ PP  +     K
Sbjct: 1836 RRNISDLNHPHKKQRKETDLTNKEKTKKPTQDSCENTEAHQKKASKKKAPPVTKDPSSLK 1895

Query: 252  KMSKVK 257
                +K
Sbjct: 1896 ATPGIK 1901


>gi|6912288 caspase 8 associated protein 2 [Homo sapiens]
          Length = 1982

 Score = 29.6 bits (65), Expect = 2.8
 Identities = 17/66 (25%), Positives = 33/66 (50%), Gaps = 2/66 (3%)

Query: 194  RANQYKENHNRTQQQVEAEVTNIKKTLKATASS--SAQEMEQQLAERECPPHAEQRQPTK 251
            R N    NH   +Q+ E ++TN +KT K T  S  + +  +++ ++++ PP  +     K
Sbjct: 1836 RRNISDLNHPHKKQRKETDLTNKEKTKKPTQDSCENTEAHQKKASKKKAPPVTKDPSSLK 1895

Query: 252  KMSKVK 257
                +K
Sbjct: 1896 ATPGIK 1901


>gi|212549532 caspase 8 associated protein 2 [Homo sapiens]
          Length = 1982

 Score = 29.6 bits (65), Expect = 2.8
 Identities = 17/66 (25%), Positives = 33/66 (50%), Gaps = 2/66 (3%)

Query: 194  RANQYKENHNRTQQQVEAEVTNIKKTLKATASS--SAQEMEQQLAERECPPHAEQRQPTK 251
            R N    NH   +Q+ E ++TN +KT K T  S  + +  +++ ++++ PP  +     K
Sbjct: 1836 RRNISDLNHPHKKQRKETDLTNKEKTKKPTQDSCENTEAHQKKASKKKAPPVTKDPSSLK 1895

Query: 252  KMSKVK 257
                +K
Sbjct: 1896 ATPGIK 1901


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 29.6 bits (65), Expect = 2.8
 Identities = 24/116 (20%), Positives = 53/116 (45%), Gaps = 3/116 (2%)

Query: 121  EMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRD--IRKKDINNIVKTLHEWC 178
            E + L  L+ L     + D+++G+++   + LE+         +  ++    V+TL    
Sbjct: 2314 EKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKI 2373

Query: 179  DGCEAVLLGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSSAQEMEQQ 234
            +G    L G+E  V+     KEN     Q+ +  ++ + + + ++  +  QE EQ+
Sbjct: 2374 EGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISEL-EIINSSFENILQEKEQE 2428


>gi|4506091 mitogen-activated protein kinase 6 [Homo sapiens]
          Length = 721

 Score = 29.6 bits (65), Expect = 2.8
 Identities = 26/69 (37%), Positives = 34/69 (49%), Gaps = 8/69 (11%)

Query: 10  NLLEQFILLAKGTSGSALTALISQVLEAPGVYVFGELLE--LANVQE----LAEGANAAY 63
           N+++ F +L  G SGS LT  +  + E   VY+  E +E  LANV E    L E A    
Sbjct: 76  NIVKVFEIL--GPSGSQLTDDVGSLTELNSVYIVQEYMETDLANVLEQGPLLEEHARLFM 133

Query: 64  LQLLNLFAY 72
            QLL    Y
Sbjct: 134 YQLLRGLKY 142


>gi|7662280 histone deacetylase 9 isoform 3 [Homo sapiens]
          Length = 590

 Score = 29.6 bits (65), Expect = 2.8
 Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 188 IEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSSA----QEMEQQLAERECPPH 243
           I++Q+L A   K++ N T+Q       +IK+ L            Q++EQQ  E+E   H
Sbjct: 59  IQKQLLIAEFQKQHENLTRQHQAQLQEHIKELLAIKQQQELLEKEQKLEQQRQEQEVERH 118

Query: 244 AEQRQPTKKMSKVKG 258
             ++Q      K +G
Sbjct: 119 RREQQLPPLRGKDRG 133


>gi|17158041 histone deacetylase 9 isoform 2 [Homo sapiens]
          Length = 879

 Score = 29.6 bits (65), Expect = 2.8
 Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 188 IEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSSA----QEMEQQLAERECPPH 243
           I++Q+L A   K++ N T+Q       +IK+ L            Q++EQQ  E+E   H
Sbjct: 59  IQKQLLIAEFQKQHENLTRQHQAQLQEHIKELLAIKQQQELLEKEQKLEQQRQEQEVERH 118

Query: 244 AEQRQPTKKMSKVKG 258
             ++Q      K +G
Sbjct: 119 RREQQLPPLRGKDRG 133


>gi|17158039 histone deacetylase 9 isoform 1 [Homo sapiens]
          Length = 1011

 Score = 29.6 bits (65), Expect = 2.8
 Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 188 IEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSSA----QEMEQQLAERECPPH 243
           I++Q+L A   K++ N T+Q       +IK+ L            Q++EQQ  E+E   H
Sbjct: 59  IQKQLLIAEFQKQHENLTRQHQAQLQEHIKELLAIKQQQELLEKEQKLEQQRQEQEVERH 118

Query: 244 AEQRQPTKKMSKVKG 258
             ++Q      K +G
Sbjct: 119 RREQQLPPLRGKDRG 133


>gi|30795202 histone deacetylase 9 isoform 4 [Homo sapiens]
          Length = 1066

 Score = 29.6 bits (65), Expect = 2.8
 Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 4/75 (5%)

Query: 188 IEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKATASSSA----QEMEQQLAERECPPH 243
           I++Q+L A   K++ N T+Q       +IK+ L            Q++EQQ  E+E   H
Sbjct: 59  IQKQLLIAEFQKQHENLTRQHQAQLQEHIKELLAIKQQQELLEKEQKLEQQRQEQEVERH 118

Query: 244 AEQRQPTKKMSKVKG 258
             ++Q      K +G
Sbjct: 119 RREQQLPPLRGKDRG 133


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.357 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,536,427
Number of Sequences: 37866
Number of extensions: 318157
Number of successful extensions: 1790
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 1725
Number of HSP's gapped (non-prelim): 103
length of query: 264
length of database: 18,247,518
effective HSP length: 100
effective length of query: 164
effective length of database: 14,460,918
effective search space: 2371590552
effective search space used: 2371590552
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.