BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|29366828 synaptotagmin XII [Homo sapiens] (421 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|29366828 synaptotagmin XII [Homo sapiens] 833 0.0 gi|92859638 synaptotagmin V [Homo sapiens] 172 4e-43 gi|45504376 synaptotagmin VI [Homo sapiens] 171 9e-43 gi|211059429 synaptotagmin II [Homo sapiens] 167 2e-41 gi|31543670 synaptotagmin II [Homo sapiens] 167 2e-41 gi|209447073 synaptotagmin I [Homo sapiens] 160 3e-39 gi|5032139 synaptotagmin I [Homo sapiens] 160 3e-39 gi|209447070 synaptotagmin I [Homo sapiens] 160 3e-39 gi|39752671 synaptotagmin X [Homo sapiens] 159 6e-39 gi|28376627 synaptotagmin IX [Homo sapiens] 155 6e-38 gi|238550198 synaptotagmin III [Homo sapiens] 150 3e-36 gi|238550196 synaptotagmin III [Homo sapiens] 150 3e-36 gi|14150054 synaptotagmin III [Homo sapiens] 150 3e-36 gi|24308219 synaptotagmin IV [Homo sapiens] 143 3e-34 gi|40068038 B/K protein [Homo sapiens] 142 7e-34 gi|38570146 synaptotagmin VII [Homo sapiens] 138 1e-32 gi|216548478 synaptotagmin XI [Homo sapiens] 123 4e-28 gi|94536846 synaptotagmin VIII [Homo sapiens] 119 5e-27 gi|31881675 synaptotagmin XV isoform a [Homo sapiens] 115 7e-26 gi|24308233 synaptotagmin XIII [Homo sapiens] 111 1e-24 gi|123173752 synaptotagmin XIV-like [Homo sapiens] 105 6e-23 gi|193804862 synaptotagmin-like 4 [Homo sapiens] 96 5e-20 gi|193804860 synaptotagmin-like 4 [Homo sapiens] 96 5e-20 gi|6005997 double C2-like domains, beta [Homo sapiens] 95 1e-19 gi|47078261 double C2-like domains, alpha [Homo sapiens] 94 2e-19 gi|31881667 synaptotagmin XV isoform b [Homo sapiens] 89 1e-17 gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens] 88 2e-17 gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens] 88 2e-17 gi|226342957 synaptotagmin XIV isoform 3 [Homo sapiens] 84 2e-16 gi|226342955 synaptotagmin XIV isoform 1 [Homo sapiens] 84 2e-16 >gi|29366828 synaptotagmin XII [Homo sapiens] Length = 421 Score = 833 bits (2152), Expect = 0.0 Identities = 421/421 (100%), Positives = 421/421 (100%) Query: 1 MAVDVAEYHLSVIKSPPGWEVGVYAAGALALLGIAAVSLWKLWTSGSFPSPSPFPNYDYR 60 MAVDVAEYHLSVIKSPPGWEVGVYAAGALALLGIAAVSLWKLWTSGSFPSPSPFPNYDYR Sbjct: 1 MAVDVAEYHLSVIKSPPGWEVGVYAAGALALLGIAAVSLWKLWTSGSFPSPSPFPNYDYR 60 Query: 61 YLQQKYGESCAEAREKRVPAWNAQRASTRGPPSRKGSLSIEDTFESISELGPLELMGREL 120 YLQQKYGESCAEAREKRVPAWNAQRASTRGPPSRKGSLSIEDTFESISELGPLELMGREL Sbjct: 61 YLQQKYGESCAEAREKRVPAWNAQRASTRGPPSRKGSLSIEDTFESISELGPLELMGREL 120 Query: 121 DLAPYGTLRKSQSADSLNSISSVSNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLL 180 DLAPYGTLRKSQSADSLNSISSVSNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLL Sbjct: 121 DLAPYGTLRKSQSADSLNSISSVSNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLL 180 Query: 181 EREEASFESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVF 240 EREEASFESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVF Sbjct: 181 EREEASFESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVF 240 Query: 241 GIDEDERNVSTGVVELKLSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTAERL 300 GIDEDERNVSTGVVELKLSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTAERL Sbjct: 241 GIDEDERNVSTGVVELKLSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTAERL 300 Query: 301 TVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPA 360 TVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPA Sbjct: 301 TVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPA 360 Query: 361 IVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSASGMGTTHWNQMLATLRRPVSMWHAVRR 420 IVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSASGMGTTHWNQMLATLRRPVSMWHAVRR Sbjct: 361 IVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSASGMGTTHWNQMLATLRRPVSMWHAVRR 420 Query: 421 N 421 N Sbjct: 421 N 421 >gi|92859638 synaptotagmin V [Homo sapiens] Length = 386 Score = 172 bits (437), Expect = 4e-43 Identities = 95/268 (35%), Positives = 154/268 (57%), Gaps = 2/268 (0%) Query: 153 LGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNA 212 LG+++ S++YD S L V ++Q L + ++RV LLPD++ +++ R Sbjct: 109 LGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQT 168 Query: 213 YSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWL 272 + F E F+ + L + L +V+ D RN + G V + +S +DL +P W Sbjct: 169 LNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLG-RPVQAWR 227 Query: 273 YLQDQ-NKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDG 331 LQ + + +G+I SL Y+PTA +LTV+V++AKNL + +DP+VKV+LLQ G Sbjct: 228 ELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGG 287 Query: 332 RKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGP 391 +K+ KKKT +K++ NP +NEA F VP +Q + + +TV + G+ + +G V +G Sbjct: 288 KKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGA 347 Query: 392 SASGMGTTHWNQMLATLRRPVSMWHAVR 419 +A G G HW MLA RRP++ WH++R Sbjct: 348 AAGGAGLRHWADMLANPRRPIAQWHSLR 375 >gi|45504376 synaptotagmin VI [Homo sapiens] Length = 425 Score = 171 bits (434), Expect = 9e-43 Identities = 100/293 (34%), Positives = 161/293 (54%), Gaps = 9/293 (3%) Query: 128 LRKSQSADSLNSISSVSNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASF 187 L K +S D ++ S + + G++ S+ YD + TL V +++ DL ++ Sbjct: 126 LYKQKSVDGEDAKSEATKS------CGKINFSLRYDYETETLIVRILKAFDLPAKDFCGS 179 Query: 188 ESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDER 247 ++++ LLPD + +R+ R + FDE F P+ L ++ L SVF D R Sbjct: 180 SDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSVFDFDRFSR 239 Query: 248 NVSTGVVELK--LSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTAERLTVVVV 305 + G V L DL + S W +Q + +GEI+ SL YLPTA RLT+ V+ Sbjct: 240 HDMIGEVILDNLFEASDLSRET-SIWKDIQYATSESVDLGEIMFSLCYLPTAGRLTLTVI 298 Query: 306 KAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQD 365 K +NL + +DP+VKV LL DGR++ KKKT +K++ NPV+NEA+IF +P + Sbjct: 299 KCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQ 358 Query: 366 LSLRVTVAESSSDGRGDNVGHVIIGPSASGMGTTHWNQMLATLRRPVSMWHAV 418 +SL ++V + G + +G +G +A G+G HWN+MLA R+P++ WH++ Sbjct: 359 VSLLISVMDYDRVGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHSL 411 >gi|211059429 synaptotagmin II [Homo sapiens] Length = 419 Score = 167 bits (422), Expect = 2e-41 Identities = 87/268 (32%), Positives = 158/268 (58%), Gaps = 2/268 (0%) Query: 153 LGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNA 212 LG+++ S++YD ++ L V V+Q +L + +++V LLPD++ +++ R Sbjct: 140 LGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKT 199 Query: 213 YSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWL 272 + F+E F+ + L K+L +++ D ++ G V++ ++ +DL QP W Sbjct: 200 LNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLG-QPIEEWR 258 Query: 273 YLQDQNKAA-DAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDG 331 LQ K + +G+I SL Y+PTA +LTV +++AKNL + +DP+VK++L+Q+G Sbjct: 259 DLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNG 318 Query: 332 RKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGP 391 +++ KKKT VK+ NP FNE+ F +P +Q + + VTV + G+ + +G + +G Sbjct: 319 KRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS 378 Query: 392 SASGMGTTHWNQMLATLRRPVSMWHAVR 419 +A+G HW+ MLA RRP++ WH+++ Sbjct: 379 NATGTELRHWSDMLANPRRPIAQWHSLK 406 Score = 60.8 bits (146), Expect = 2e-09 Identities = 40/122 (32%), Positives = 64/122 (52%), Gaps = 2/122 (1%) Query: 276 DQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMS 335 ++ K + +G++ SL Y A +LTV V++A L + T+DP+VKV+LL D +K Sbjct: 132 EEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKK-- 189 Query: 336 KKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSASG 395 K +T V R NP FNE F VP L +L + + + + D +G V + + Sbjct: 190 KYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVD 249 Query: 396 MG 397 +G Sbjct: 250 LG 251 >gi|31543670 synaptotagmin II [Homo sapiens] Length = 419 Score = 167 bits (422), Expect = 2e-41 Identities = 87/268 (32%), Positives = 158/268 (58%), Gaps = 2/268 (0%) Query: 153 LGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNA 212 LG+++ S++YD ++ L V V+Q +L + +++V LLPD++ +++ R Sbjct: 140 LGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVHRKT 199 Query: 213 YSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWL 272 + F+E F+ + L K+L +++ D ++ G V++ ++ +DL QP W Sbjct: 200 LNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLG-QPIEEWR 258 Query: 273 YLQDQNKAA-DAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDG 331 LQ K + +G+I SL Y+PTA +LTV +++AKNL + +DP+VK++L+Q+G Sbjct: 259 DLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNG 318 Query: 332 RKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGP 391 +++ KKKT VK+ NP FNE+ F +P +Q + + VTV + G+ + +G + +G Sbjct: 319 KRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGS 378 Query: 392 SASGMGTTHWNQMLATLRRPVSMWHAVR 419 +A+G HW+ MLA RRP++ WH+++ Sbjct: 379 NATGTELRHWSDMLANPRRPIAQWHSLK 406 Score = 60.8 bits (146), Expect = 2e-09 Identities = 40/122 (32%), Positives = 64/122 (52%), Gaps = 2/122 (1%) Query: 276 DQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMS 335 ++ K + +G++ SL Y A +LTV V++A L + T+DP+VKV+LL D +K Sbjct: 132 EEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKK-- 189 Query: 336 KKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSASG 395 K +T V R NP FNE F VP L +L + + + + D +G V + + Sbjct: 190 KYETKVHRKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVD 249 Query: 396 MG 397 +G Sbjct: 250 LG 251 >gi|209447073 synaptotagmin I [Homo sapiens] Length = 422 Score = 160 bits (404), Expect = 3e-39 Identities = 84/268 (31%), Positives = 157/268 (58%), Gaps = 2/268 (0%) Query: 153 LGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNA 212 LG+++ S++YD ++ L V ++Q +L + +++V LLPD++ +++ R Sbjct: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKT 202 Query: 213 YSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWL 272 + F+E+F+ + + L K+L +V+ D ++ G ++ ++ +D W Sbjct: 203 LNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFG-HVTEEWR 261 Query: 273 YLQDQNKAA-DAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDG 331 LQ K + +G+I SL Y+PTA +LTVV+++AKNL + +DP+VK++L+Q+G Sbjct: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321 Query: 332 RKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGP 391 +++ KKKT +K++ NP +NE+ F VP +Q + + VTV + G+ D +G V +G Sbjct: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381 Query: 392 SASGMGTTHWNQMLATLRRPVSMWHAVR 419 +++G HW+ MLA RRP++ WH ++ Sbjct: 382 NSTGAELRHWSDMLANPRRPIAQWHTLQ 409 Score = 56.6 bits (135), Expect = 4e-08 Identities = 40/132 (30%), Positives = 65/132 (49%), Gaps = 4/132 (3%) Query: 275 QDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKM 334 +++ K + +G++ SL Y +L V +++A L + T+DP+VKV+LL D +K Sbjct: 134 KEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKK- 192 Query: 335 SKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSAS 394 K +T V R NPVFNE F VP L +L + V + + D +G + + Sbjct: 193 -KFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTV 251 Query: 395 GMG--TTHWNQM 404 G T W + Sbjct: 252 DFGHVTEEWRDL 263 >gi|5032139 synaptotagmin I [Homo sapiens] Length = 422 Score = 160 bits (404), Expect = 3e-39 Identities = 84/268 (31%), Positives = 157/268 (58%), Gaps = 2/268 (0%) Query: 153 LGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNA 212 LG+++ S++YD ++ L V ++Q +L + +++V LLPD++ +++ R Sbjct: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKT 202 Query: 213 YSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWL 272 + F+E+F+ + + L K+L +V+ D ++ G ++ ++ +D W Sbjct: 203 LNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFG-HVTEEWR 261 Query: 273 YLQDQNKAA-DAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDG 331 LQ K + +G+I SL Y+PTA +LTVV+++AKNL + +DP+VK++L+Q+G Sbjct: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321 Query: 332 RKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGP 391 +++ KKKT +K++ NP +NE+ F VP +Q + + VTV + G+ D +G V +G Sbjct: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381 Query: 392 SASGMGTTHWNQMLATLRRPVSMWHAVR 419 +++G HW+ MLA RRP++ WH ++ Sbjct: 382 NSTGAELRHWSDMLANPRRPIAQWHTLQ 409 Score = 56.6 bits (135), Expect = 4e-08 Identities = 40/132 (30%), Positives = 65/132 (49%), Gaps = 4/132 (3%) Query: 275 QDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKM 334 +++ K + +G++ SL Y +L V +++A L + T+DP+VKV+LL D +K Sbjct: 134 KEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKK- 192 Query: 335 SKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSAS 394 K +T V R NPVFNE F VP L +L + V + + D +G + + Sbjct: 193 -KFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTV 251 Query: 395 GMG--TTHWNQM 404 G T W + Sbjct: 252 DFGHVTEEWRDL 263 >gi|209447070 synaptotagmin I [Homo sapiens] Length = 422 Score = 160 bits (404), Expect = 3e-39 Identities = 84/268 (31%), Positives = 157/268 (58%), Gaps = 2/268 (0%) Query: 153 LGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNA 212 LG+++ S++YD ++ L V ++Q +L + +++V LLPD++ +++ R Sbjct: 143 LGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKKKFETKVHRKT 202 Query: 213 YSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWL 272 + F+E+F+ + + L K+L +V+ D ++ G ++ ++ +D W Sbjct: 203 LNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTVDFG-HVTEEWR 261 Query: 273 YLQDQNKAA-DAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDG 331 LQ K + +G+I SL Y+PTA +LTVV+++AKNL + +DP+VK++L+Q+G Sbjct: 262 DLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNG 321 Query: 332 RKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGP 391 +++ KKKT +K++ NP +NE+ F VP +Q + + VTV + G+ D +G V +G Sbjct: 322 KRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGY 381 Query: 392 SASGMGTTHWNQMLATLRRPVSMWHAVR 419 +++G HW+ MLA RRP++ WH ++ Sbjct: 382 NSTGAELRHWSDMLANPRRPIAQWHTLQ 409 Score = 56.6 bits (135), Expect = 4e-08 Identities = 40/132 (30%), Positives = 65/132 (49%), Gaps = 4/132 (3%) Query: 275 QDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKM 334 +++ K + +G++ SL Y +L V +++A L + T+DP+VKV+LL D +K Sbjct: 134 KEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLLPDKKK- 192 Query: 335 SKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSAS 394 K +T V R NPVFNE F VP L +L + V + + D +G + + Sbjct: 193 -KFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIGEFKVPMNTV 251 Query: 395 GMG--TTHWNQM 404 G T W + Sbjct: 252 DFGHVTEEWRDL 263 >gi|39752671 synaptotagmin X [Homo sapiens] Length = 523 Score = 159 bits (401), Expect = 6e-39 Identities = 91/280 (32%), Positives = 150/280 (53%), Gaps = 3/280 (1%) Query: 139 SISSVSNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLP 198 S+ S N G++ +++YD + L V +++ DL ++ ++++ LLP Sbjct: 218 SVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLP 277 Query: 199 DEQIVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELK- 257 D + +R+ R + FDE F P+ L + L FSV+ D R+ G V L Sbjct: 278 DRKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDN 337 Query: 258 -LSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDK 316 V DL + + W + + +GEI+ SL YLPTA R+T+ V+K +NL + Sbjct: 338 LFEVSDLSREA-TVWKDIHCATTESIDLGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDIT 396 Query: 317 TTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESS 376 ++DP+VKV L+ +GR++ K+KT K++ NPV+NEA+IF +P + +SL + V + Sbjct: 397 GSSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYD 456 Query: 377 SDGRGDNVGHVIIGPSASGMGTTHWNQMLATLRRPVSMWH 416 G + +G G A G+G HWN+MLA R+P++ WH Sbjct: 457 RVGHNEVIGVCRTGLDAEGLGRDHWNEMLAYHRKPITHWH 496 >gi|28376627 synaptotagmin IX [Homo sapiens] Length = 491 Score = 155 bits (392), Expect = 6e-38 Identities = 85/267 (31%), Positives = 148/267 (55%), Gaps = 3/267 (1%) Query: 154 GQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAY 213 G++ ++YD L V + + +L ++ + ++++ LLPD + +++ R Sbjct: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTL 281 Query: 214 SIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTG--VVELKLSVLDLPLQPFSGW 271 + FDE F P+ LE + L FSV+ D R+ G VV+ L + D P + W Sbjct: 282 NPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECIL-W 340 Query: 272 LYLQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDG 331 ++ +GE++ SL YLPTA RLT+ ++KA+NL + +DP+VKV L+ DG Sbjct: 341 KDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDG 400 Query: 332 RKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGP 391 R++ K+KT+ KR+ NPV+NEA++F VP + + L + V + G + +G +G Sbjct: 401 RRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGN 460 Query: 392 SASGMGTTHWNQMLATLRRPVSMWHAV 418 A +G HW++ML+ R+P++ WH++ Sbjct: 461 EAERLGRDHWSEMLSYPRKPIAHWHSL 487 Score = 62.0 bits (149), Expect = 1e-09 Identities = 39/107 (36%), Positives = 58/107 (54%), Gaps = 2/107 (1%) Query: 283 AVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVK 342 A G++ L Y E+L V + KA NL + T+DP+VK+YLL D + +K +T V Sbjct: 220 ACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPD--RKTKHQTKVH 277 Query: 343 RDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVII 389 R NPVF+E +F VP L+ L +V + R D +G V++ Sbjct: 278 RKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVV 324 >gi|238550198 synaptotagmin III [Homo sapiens] Length = 590 Score = 150 bits (378), Expect = 3e-36 Identities = 89/277 (32%), Positives = 151/277 (54%), Gaps = 6/277 (2%) Query: 144 SNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIV 203 S G G++ ++ Y S L V ++Q DL ++ F ++++ LLPD + Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKK 350 Query: 204 GISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDL 263 +++ R + F+E F + L ++ L FSV+ D R+ G V L ++L+L Sbjct: 351 FQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLD-NLLEL 409 Query: 264 PLQPFSGWLY---LQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTAD 320 QP L+ ++ ++ AD +GE+ SL YLPTA RLTV ++KA NL + +D Sbjct: 410 AEQPPDRPLWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSD 468 Query: 321 PFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGR 380 P+VK L+ +GR++ K+KT++K++ NP +NEA++F V ++++ L + V + G Sbjct: 469 PYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGH 528 Query: 381 GDNVGHVIIGPSASG-MGTTHWNQMLATLRRPVSMWH 416 + +G +GP A+ G HW +MLA R+PV WH Sbjct: 529 NEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWH 565 >gi|238550196 synaptotagmin III [Homo sapiens] Length = 590 Score = 150 bits (378), Expect = 3e-36 Identities = 89/277 (32%), Positives = 151/277 (54%), Gaps = 6/277 (2%) Query: 144 SNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIV 203 S G G++ ++ Y S L V ++Q DL ++ F ++++ LLPD + Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKK 350 Query: 204 GISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDL 263 +++ R + F+E F + L ++ L FSV+ D R+ G V L ++L+L Sbjct: 351 FQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLD-NLLEL 409 Query: 264 PLQPFSGWLY---LQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTAD 320 QP L+ ++ ++ AD +GE+ SL YLPTA RLTV ++KA NL + +D Sbjct: 410 AEQPPDRPLWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSD 468 Query: 321 PFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGR 380 P+VK L+ +GR++ K+KT++K++ NP +NEA++F V ++++ L + V + G Sbjct: 469 PYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGH 528 Query: 381 GDNVGHVIIGPSASG-MGTTHWNQMLATLRRPVSMWH 416 + +G +GP A+ G HW +MLA R+PV WH Sbjct: 529 NEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWH 565 >gi|14150054 synaptotagmin III [Homo sapiens] Length = 590 Score = 150 bits (378), Expect = 3e-36 Identities = 89/277 (32%), Positives = 151/277 (54%), Gaps = 6/277 (2%) Query: 144 SNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIV 203 S G G++ ++ Y S L V ++Q DL ++ F ++++ LLPD + Sbjct: 291 SGEAGTGAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKK 350 Query: 204 GISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDL 263 +++ R + F+E F + L ++ L FSV+ D R+ G V L ++L+L Sbjct: 351 FQTKVHRKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLD-NLLEL 409 Query: 264 PLQPFSGWLY---LQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTAD 320 QP L+ ++ ++ AD +GE+ SL YLPTA RLTV ++KA NL + +D Sbjct: 410 AEQPPDRPLWRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSD 468 Query: 321 PFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGR 380 P+VK L+ +GR++ K+KT++K++ NP +NEA++F V ++++ L + V + G Sbjct: 469 PYVKASLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGH 528 Query: 381 GDNVGHVIIGPSASG-MGTTHWNQMLATLRRPVSMWH 416 + +G +GP A+ G HW +MLA R+PV WH Sbjct: 529 NEVIGVCRVGPDAADPHGREHWAEMLANPRKPVEHWH 565 >gi|24308219 synaptotagmin IV [Homo sapiens] Length = 425 Score = 143 bits (360), Expect = 3e-34 Identities = 91/293 (31%), Positives = 161/293 (54%), Gaps = 4/293 (1%) Query: 129 RKSQSADSLNSISSVSNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFE 188 ++S S +SL S +S+++ Q+ LG + S+EY+ V + + + L +E S Sbjct: 131 KESVSPESLKSSTSLTSEEKQE-KLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMT 189 Query: 189 SC-FMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDP-TALEEKSLRFSVFGIDEDE 246 S ++++++LP+++ +R+ R FDE F+ P T ++E +L F++ D Sbjct: 190 SDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFS 249 Query: 247 RNVSTGVVELKLSVLDLPLQPFSGWLYLQDQN-KAADAVGEILLSLSYLPTAERLTVVVV 305 R+ G V + LS ++L + +N + + GE+L+SL Y T LTVVV+ Sbjct: 250 RDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELLISLCYQSTTNTLTVVVL 309 Query: 306 KAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQD 365 KA++L ++ +DP+VKV L +++SKKKT VK+ PN VFNE +F +P L+D Sbjct: 310 KARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCTPNAVFNELFVFDIPCEGLED 369 Query: 366 LSLRVTVAESSSDGRGDNVGHVIIGPSASGMGTTHWNQMLATLRRPVSMWHAV 418 +S+ V +S R + +G +++G +A G G HW ++ RR ++ WH + Sbjct: 370 ISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEICDYPRRQIAKWHVL 422 >gi|40068038 B/K protein [Homo sapiens] Length = 474 Score = 142 bits (357), Expect = 7e-34 Identities = 91/303 (30%), Positives = 156/303 (51%), Gaps = 14/303 (4%) Query: 125 YGTLRKSQSADSLNSISSVSNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLL---- 180 Y S DSL +S + LG + S +YD + L V V++ +DL Sbjct: 162 YSLDSNSDDVDSLTDEEILSK-----YQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPIS 216 Query: 181 ---EREEASFESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRF 237 R++ + + ++++ LLPD++ + ++R F+E+++ + + ++L Sbjct: 217 HDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLL 276 Query: 238 SVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWLYLQDQNKAADAVGEILLSLSYLPTA 297 +V D+ R+ G V + L +DL ++ W L ++ +GE+LLSL+YLP+A Sbjct: 277 TVVDFDKFSRHCVIGKVSVPLCEVDL-VKGGHWWKALIPSSQNEVELGELLLSLNYLPSA 335 Query: 298 ERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFS 357 RL V V++AK L+ T+ +DPFVK+ L+ + + KKT+ R +P +NE+ F Sbjct: 336 GRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFK 395 Query: 358 VPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSASGMG-TTHWNQMLATLRRPVSMWH 416 VP L++ SL TV + D +G ++IG +SG T HW +ML T R V WH Sbjct: 396 VPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWH 455 Query: 417 AVR 419 ++R Sbjct: 456 SLR 458 >gi|38570146 synaptotagmin VII [Homo sapiens] Length = 403 Score = 138 bits (347), Expect = 1e-32 Identities = 79/269 (29%), Positives = 148/269 (55%), Gaps = 4/269 (1%) Query: 153 LGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNA 212 LG+++ S+ Y+ TL V +M+ ++L ++ + F+++ LLPD++ ++++R Sbjct: 136 LGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKN 195 Query: 213 YSIFFDEKFSIPLDP-TALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLP-LQPFSG 270 + ++E F P + ++ L V D RN G V + L+ +DL +Q F Sbjct: 196 LNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTF-- 253 Query: 271 WLYLQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQD 330 W L+ + + + GE+LLSL Y P+A + V ++KA+NL + T+DP+VKV+L+ Sbjct: 254 WKDLKPCSDGSGSRGELLLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYK 313 Query: 331 GRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIG 390 +++ KKKT + + NP+FNE+ F +P L++ ++ +TV + R D +G + + Sbjct: 314 DKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLS 373 Query: 391 PSASGMGTTHWNQMLATLRRPVSMWHAVR 419 + HW M+A R+PV+ WH ++ Sbjct: 374 WKSGPGEVKHWKDMIARPRQPVAQWHQLK 402 >gi|216548478 synaptotagmin XI [Homo sapiens] Length = 431 Score = 123 bits (308), Expect = 4e-28 Identities = 81/279 (29%), Positives = 151/279 (54%), Gaps = 13/279 (4%) Query: 149 QDFTLGQVEVSMEYDTASHTLNVAVMQGKDL-LEREEASFESCFMRVSLLPDEQIVGISR 207 +D LG + S++Y+ L V + + L + ++ ++++++LPD++ +R Sbjct: 154 EDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTR 213 Query: 208 IQRNAYSIFFDEKFSIPLDP-TALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQ 266 + R FDE F+ P + L++ L F V D R+ G V + L+ +D Sbjct: 214 VLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVD---- 269 Query: 267 PFSGWLYL-----QDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTN-DKTTAD 320 P +G + L + + + GE+ +SLSY P A+R+TVVV+KA++L + + + Sbjct: 270 PSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGN 329 Query: 321 PFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGR 380 P+VKV + ++++KKKT VK+ NP+FNE+ I+ +P +L D+S+ V + + Sbjct: 330 PYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTK 389 Query: 381 GDNVGHVIIGP-SASGMGTTHWNQMLATLRRPVSMWHAV 418 + VG +I+G S + G HW ++ + R+PV+ WH++ Sbjct: 390 NEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSL 428 >gi|94536846 synaptotagmin VIII [Homo sapiens] Length = 401 Score = 119 bits (298), Expect = 5e-27 Identities = 83/266 (31%), Positives = 128/266 (48%), Gaps = 7/266 (2%) Query: 154 GQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAY 213 G++++S+E+D S + V + Q DL + RVS+ +++ R Sbjct: 119 GRLQLSLEFDFGSQEIRVGLRQAADL---RPGGTVDPYARVSVSTQAGHRHETKVHRGTL 175 Query: 214 SIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWLY 273 FDE + L +L+ +F + G + L L +DL +L Sbjct: 176 CPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLL 235 Query: 274 LQDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRK 333 + VGE+ SL Y+P++ RLTVVV++A+ L A+P+VKV L+ + RK Sbjct: 236 GPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGL----RPGLAEPYVKVQLMLNQRK 291 Query: 334 MSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSA 393 K+KTA K+ P FNEA F VP +Q++ L + V + S R + VG V +G A Sbjct: 292 WKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARA 351 Query: 394 SGMGTTHWNQMLATLRRPVSMWHAVR 419 SG HW MLA RRP++ H +R Sbjct: 352 SGQPLQHWADMLAHARRPIAQRHPLR 377 >gi|31881675 synaptotagmin XV isoform a [Homo sapiens] Length = 421 Score = 115 bits (288), Expect = 7e-26 Identities = 84/288 (29%), Positives = 139/288 (48%), Gaps = 20/288 (6%) Query: 144 SNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESC--FMRVSLLPDEQ 201 S T D LG++ S+EY+ + L V +++ + L +A E+C +++ LLPDE+ Sbjct: 139 SETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHL----QAPSETCSPLVKLYLLPDER 194 Query: 202 IVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVL 261 S+ +R + FDE F + + ++ L+FSV+ +D ++ G V + Sbjct: 195 RFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQV-----LF 249 Query: 262 DLPLQPFSG------WLYLQDQN-KAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTN 314 L + G W L+ ++ + G++ LSY RLTVVV++AK L Sbjct: 250 PLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQE 309 Query: 315 DKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAE 374 D+ FVKV L+ + + KKT+ NPV+NE F A L SL +TV + Sbjct: 310 DRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQ 369 Query: 375 SSSDGRGDNVGHVIIGP--SASGMGTTHWNQMLATLRRPVSMWHAVRR 420 + + +G V++GP G HW++ML+ + V WHA+ R Sbjct: 370 NMEGDKSQQLGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHALCR 417 >gi|24308233 synaptotagmin XIII [Homo sapiens] Length = 426 Score = 111 bits (278), Expect = 1e-24 Identities = 72/203 (35%), Positives = 104/203 (51%), Gaps = 4/203 (1%) Query: 217 FDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFSGWLYLQD 276 ++E +PL L +L ++ D R+ G + L L +PL + W L+ Sbjct: 221 WEEGLVLPLAEEELPTATLTLTLRTCDRFSRHSVAGELRLGLDGTSVPLGA-AQWGELKT 279 Query: 277 QNKAADA-VGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTA--DPFVKVYLLQDGRK 333 K A GE+LLS+SYLP A RL VV++KAKNL K D VKV L RK Sbjct: 280 SAKEPSAGAGEVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLKHQARK 339 Query: 334 MSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSA 393 + KK+T + NPV+NE ++F +P +LQ S+ + V G+ +GH +G Sbjct: 340 LKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALGHCSLGLHT 399 Query: 394 SGMGTTHWNQMLATLRRPVSMWH 416 SG +HW +ML RR ++MWH Sbjct: 400 SGSERSHWEEMLKNPRRQIAMWH 422 >gi|123173752 synaptotagmin XIV-like [Homo sapiens] Length = 645 Score = 105 bits (263), Expect = 6e-23 Identities = 96/392 (24%), Positives = 170/392 (43%), Gaps = 37/392 (9%) Query: 63 QQKYGESCAEAREKRVPAWNAQRASTRGPPSRKGSL----SIEDTFESISELGPLEL--- 115 Q++Y E+ + + +PA ++Q RG G+ S+ + S G LE+ Sbjct: 252 QRRYSENLSYGEDDHIPA-HSQSPCERGDAKHHGTSHQESSVVQSLRRQSTEGSLEMETA 310 Query: 116 ---MGRELDLAPYGTLRKSQSADSLNSISSVSNTFGQDFTLGQVEVSMEYDTASHTLNVA 172 G E A + S ++ S G ++V EY AS L V Sbjct: 311 FNSRGFEDSYATDSSSMWSPEEQDRTNLQVPSGVSEPISKCGDLDVIFEYRAASQKLTVT 370 Query: 173 VMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAYSIFFDEKFSIPLDPTALEE 232 +++ + L +++ + S + V LLP ++ G + IQR +F ++ L+P + Sbjct: 371 IVRAQGLPDKDRSGVNSWQVHVVLLPGKKHRGRTNIQRGPNPVFREKVTFAKLEPRDVAA 430 Query: 233 KSLRFSVFGIDEDERNVSTGVVELKLSVLD--------LPLQP----FSGWLYLQD---- 276 ++RF ++ + R G LS L L L+P SG L Sbjct: 431 CAVRFRLYAARKMTRERMMGEKLFYLSHLHPEGEMKVTLVLEPRSNISSGGSPLSPSAVS 490 Query: 277 --------QNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLL 328 Q+ + E+L+ LSY T RL+V ++K + D + K++LL Sbjct: 491 HSDSTSSTQSLSHGGAPELLVGLSYNATTGRLSVEMIKGSHFRNLAVNRAPDTYGKLFLL 550 Query: 329 QD-GRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHV 387 G++MS+ KT+++R PNPV+ E +F V L D++L ++V + R + +G + Sbjct: 551 NSVGQEMSRCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLMISVYNRRTMKRKEMIGWI 610 Query: 388 IIGPSASG-MGTTHWNQMLATLRRPVSMWHAV 418 +G ++SG HW +M T + + WH + Sbjct: 611 ALGQNSSGEEEQDHWEEMKETKGQQICRWHTL 642 >gi|193804862 synaptotagmin-like 4 [Homo sapiens] Length = 671 Score = 96.3 bits (238), Expect = 5e-20 Identities = 84/310 (27%), Positives = 143/310 (46%), Gaps = 26/310 (8%) Query: 136 SLNSISSVSNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESC-FMRV 194 S+ SI S + FG F G++ S++Y+ + +L V V + L +EA S +++ Sbjct: 340 SMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKT 399 Query: 195 SLLPDEQIVGISR--IQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTG 252 LLPD+ G + I+R+ + +DE + + L +++L+FSV+ RN G Sbjct: 400 YLLPDKSRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLG 459 Query: 253 VVELKLSV--LDLPLQ---PFSGWLYLQDQNKAADAVGEILLSLSYLPTAE--------- 298 E+++ LD L P G + + GE+++SL Y+P ++ Sbjct: 460 EAEIQMDSWKLDKKLDHCLPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKK 519 Query: 299 -------RLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFN 351 L V + +AKNL T+D FVK YLL K SK+KT V + NP +N Sbjct: 520 SKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYN 579 Query: 352 EAMIFS-VPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSASGMGTTHWNQMLATLRR 410 +++ V LQ + L +TV + D +G V +G +G+ + + Sbjct: 580 HTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLG-VGTGISNGEVVDWMDSTGE 638 Query: 411 PVSMWHAVRR 420 VS+W +R+ Sbjct: 639 EVSLWQKMRQ 648 >gi|193804860 synaptotagmin-like 4 [Homo sapiens] Length = 671 Score = 96.3 bits (238), Expect = 5e-20 Identities = 84/310 (27%), Positives = 143/310 (46%), Gaps = 26/310 (8%) Query: 136 SLNSISSVSNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESC-FMRV 194 S+ SI S + FG F G++ S++Y+ + +L V V + L +EA S +++ Sbjct: 340 SMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKT 399 Query: 195 SLLPDEQIVGISR--IQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTG 252 LLPD+ G + I+R+ + +DE + + L +++L+FSV+ RN G Sbjct: 400 YLLPDKSRQGKRKTSIKRDTINPLYDETLRYEIPESLLAQRTLQFSVWHHGRFGRNTFLG 459 Query: 253 VVELKLSV--LDLPLQ---PFSGWLYLQDQNKAADAVGEILLSLSYLPTAE--------- 298 E+++ LD L P G + + GE+++SL Y+P ++ Sbjct: 460 EAEIQMDSWKLDKKLDHCLPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKK 519 Query: 299 -------RLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFN 351 L V + +AKNL T+D FVK YLL K SK+KT V + NP +N Sbjct: 520 SKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVKGYLLPMRNKASKRKTPVMKKTLNPHYN 579 Query: 352 EAMIFS-VPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSASGMGTTHWNQMLATLRR 410 +++ V LQ + L +TV + D +G V +G +G+ + + Sbjct: 580 HTFVYNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLG-VGTGISNGEVVDWMDSTGE 638 Query: 411 PVSMWHAVRR 420 VS+W +R+ Sbjct: 639 EVSLWQKMRQ 648 >gi|6005997 double C2-like domains, beta [Homo sapiens] Length = 412 Score = 95.1 bits (235), Expect = 1e-19 Identities = 76/276 (27%), Positives = 123/276 (44%), Gaps = 11/276 (3%) Query: 153 LGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQ--R 210 LG ++ S+ YD ++ L+ + + K L + ++++ LLP R + R Sbjct: 127 LGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLR 186 Query: 211 NAYSIFFDEKFSI-PLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQPFS 269 N + ++E + + + K+LR SV D+ N G + L L P + Sbjct: 187 NTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLK-PNHTKT 245 Query: 270 GWLYLQDQ-------NKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPF 322 + L+ Q +K+ + G IL+SL Y + L V +V+ +L + +DP+ Sbjct: 246 FNICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPY 305 Query: 323 VKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGD 382 VK YL D K SK KTAVK+ NP FNE + + L SL VTV + D Sbjct: 306 VKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSND 365 Query: 383 NVGHVIIGPSASGMGTTHWNQMLATLRRPVSMWHAV 418 +G V++G A G HW L + + WH + Sbjct: 366 FIGGVVLGIHAKGERLKHWFDCLKNKDKRIERWHTL 401 Score = 45.8 bits (107), Expect = 7e-05 Identities = 31/106 (29%), Positives = 52/106 (49%), Gaps = 5/106 (4%) Query: 283 AVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVK 342 A+G + SL Y L + KAK L + ADP+VK++LL K +K +T Sbjct: 126 ALGTLDFSLLYDQENNALHCTITKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTL 185 Query: 343 RDDPNPVFNEAMIFSVPAIVLQDL---SLRVTVAESSSDGRGDNVG 385 R+ NP +NE + + I +D+ +LR++V + + +G Sbjct: 186 RNTLNPTWNETLTYY--GITDEDMIRKTLRISVCDEDKFRHNEFIG 229 >gi|47078261 double C2-like domains, alpha [Homo sapiens] Length = 400 Score = 94.0 bits (232), Expect = 2e-19 Identities = 80/297 (26%), Positives = 126/297 (42%), Gaps = 31/297 (10%) Query: 153 LGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVG--ISRIQR 210 LG +E + YD AS TL+ ++++ K L + ++++ LLP ++ QR Sbjct: 90 LGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQR 149 Query: 211 NAYSIFFDEKFSIP-LDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVL-------- 261 N + ++E + + + K LR +V D+ N G + + L L Sbjct: 150 NTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHF 209 Query: 262 ------DLPLQPFSGW--------LYLQDQNKA------ADAVGEILLSLSYLPTAERLT 301 +PL S YL++ +A + G ILLSLSY L Sbjct: 210 NICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLL 269 Query: 302 VVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAI 361 V +++ +L + +DP+VK YL D K SK KT VK+ NP FNE + + Sbjct: 270 VGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELS 329 Query: 362 VLQDLSLRVTVAESSSDGRGDNVGHVIIGPSASGMGTTHWNQMLATLRRPVSMWHAV 418 L +L VTV + D +G V +GP A G HW+ L + WH + Sbjct: 330 TLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTL 386 Score = 48.1 bits (113), Expect = 1e-05 Identities = 33/110 (30%), Positives = 56/110 (50%), Gaps = 5/110 (4%) Query: 281 ADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTA 340 A A+G + L Y + L +++AK L + ADP+VK++LL K +K KT Sbjct: 87 ATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTK 146 Query: 341 VKRDDPNPVFNEAMIFSVPAIVLQDLS---LRVTVAESSSDGRGDNVGHV 387 +R+ NPV+NE + +S I D++ LR+ V + + +G + Sbjct: 147 TQRNTLNPVWNEDLTYS--GITDDDITHKVLRIAVCDEDKLSHNEFIGEI 194 >gi|31881667 synaptotagmin XV isoform b [Homo sapiens] Length = 390 Score = 88.6 bits (218), Expect = 1e-17 Identities = 70/241 (29%), Positives = 116/241 (48%), Gaps = 18/241 (7%) Query: 144 SNTFGQDFTLGQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESC--FMRVSLLPDEQ 201 S T D LG++ S+EY+ + L V +++ + L +A E+C +++ LLPDE+ Sbjct: 139 SETDFPDGCLGRLWFSVEYEQEAERLLVGLIKAQHL----QAPSETCSPLVKLYLLPDER 194 Query: 202 IVGISRIQRNAYSIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVL 261 S+ +R + FDE F + + ++ L+FSV+ +D ++ G V + Sbjct: 195 RFLQSKTKRKTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQV-----LF 249 Query: 262 DLPLQPFSG------WLYLQDQN-KAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTN 314 L + G W L+ ++ + G++ LSY RLTVVV++AK L Sbjct: 250 PLKNETLVGDCRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQE 309 Query: 315 DKTTADPFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAE 374 D+ FVKV L+ + + KKT+ NPV+NE F A L SL +TV + Sbjct: 310 DRGIVSVFVKVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQ 369 Query: 375 S 375 + Sbjct: 370 N 370 Score = 53.1 bits (126), Expect = 5e-07 Identities = 35/105 (33%), Positives = 55/105 (52%), Gaps = 4/105 (3%) Query: 284 VGEILLSLSYLPTAERLTVVVVKAKNLIWTNDKTTADPFVKVYLLQDGRKMSKKKTAVKR 343 +G + S+ Y AERL V ++KA++L ++ T P VK+YLL D R+ + KT KR Sbjct: 148 LGRLWFSVEYEQEAERLLVGLIKAQHLQAPSE--TCSPLVKLYLLPDERRFLQSKT--KR 203 Query: 344 DDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVI 388 NP F+E IF V + + L+ +V + +G V+ Sbjct: 204 KTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVL 248 >gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens] Length = 600 Score = 87.8 bits (216), Expect = 2e-17 Identities = 72/291 (24%), Positives = 129/291 (44%), Gaps = 26/291 (8%) Query: 154 GQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAY 213 G ++V+ +YD+ L V V D+ S + + LLP ++ + IQR Sbjct: 307 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 366 Query: 214 SIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLP--------L 265 +F + ++ + ++RF ++G+ ++ G L+ L+L L Sbjct: 367 PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL 426 Query: 266 QPFSGWLYLQDQNKAAD----------------AVGEILLSLSYLPTAERLTVVVVKAKN 309 +P Q ++ +V EIL+ L Y T RL+ V+K + Sbjct: 427 EPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSH 486 Query: 310 LIWTNDKTTADPFVKVYLLQD-GRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSL 368 + +VK+ LL G++MSK KT+++R PNPV+ E +F V L D++L Sbjct: 487 FKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTL 546 Query: 369 RVTVAESSSDGRGDNVGHVIIGPSASG-MGTTHWNQMLATLRRPVSMWHAV 418 ++V S R + +G + +G ++SG HW +M + + V WHA+ Sbjct: 547 ILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 597 >gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens] Length = 555 Score = 87.8 bits (216), Expect = 2e-17 Identities = 72/291 (24%), Positives = 129/291 (44%), Gaps = 26/291 (8%) Query: 154 GQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAY 213 G ++V+ +YD+ L V V D+ S + + LLP ++ + IQR Sbjct: 262 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 321 Query: 214 SIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLP--------L 265 +F + ++ + ++RF ++G+ ++ G L+ L+L L Sbjct: 322 PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL 381 Query: 266 QPFSGWLYLQDQNKAAD----------------AVGEILLSLSYLPTAERLTVVVVKAKN 309 +P Q ++ +V EIL+ L Y T RL+ V+K + Sbjct: 382 EPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSH 441 Query: 310 LIWTNDKTTADPFVKVYLLQD-GRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSL 368 + +VK+ LL G++MSK KT+++R PNPV+ E +F V L D++L Sbjct: 442 FKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTL 501 Query: 369 RVTVAESSSDGRGDNVGHVIIGPSASG-MGTTHWNQMLATLRRPVSMWHAV 418 ++V S R + +G + +G ++SG HW +M + + V WHA+ Sbjct: 502 ILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHAL 552 >gi|226342957 synaptotagmin XIV isoform 3 [Homo sapiens] Length = 574 Score = 84.3 bits (207), Expect = 2e-16 Identities = 76/310 (24%), Positives = 132/310 (42%), Gaps = 45/310 (14%) Query: 154 GQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAY 213 G ++V+ +YD+ L V V D+ S + + LLP ++ + IQR Sbjct: 262 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 321 Query: 214 SIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLP--------L 265 +F + ++ + ++RF ++G+ ++ G L+ L+L L Sbjct: 322 PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL 381 Query: 266 QPFSGWLYLQDQNKAAD----------------AVGEILLSLSYLPTAERLTVVVVKA-- 307 +P Q ++ +V EIL+ L Y T RL+ V+K Sbjct: 382 EPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSH 441 Query: 308 -----------------KNLIWTNDKTTADPFVKVYLLQD-GRKMSKKKTAVKRDDPNPV 349 K+LI D +VK+ LL G++MSK KT+++R PNPV Sbjct: 442 FKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNPV 501 Query: 350 FNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSASG-MGTTHWNQMLATL 408 + E +F V L D++L ++V S R + +G + +G ++SG HW +M + Sbjct: 502 YKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESK 561 Query: 409 RRPVSMWHAV 418 + V WHA+ Sbjct: 562 GQQVCRWHAL 571 >gi|226342955 synaptotagmin XIV isoform 1 [Homo sapiens] Length = 619 Score = 84.3 bits (207), Expect = 2e-16 Identities = 76/310 (24%), Positives = 132/310 (42%), Gaps = 45/310 (14%) Query: 154 GQVEVSMEYDTASHTLNVAVMQGKDLLEREEASFESCFMRVSLLPDEQIVGISRIQRNAY 213 G ++V+ +YD+ L V V D+ S + + LLP ++ + IQR Sbjct: 307 GTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPC 366 Query: 214 SIFFDEKFSIPLDPTALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLP--------L 265 +F + ++ + ++RF ++G+ ++ G L+ L+L L Sbjct: 367 PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVIL 426 Query: 266 QPFSGWLYLQDQNKAAD----------------AVGEILLSLSYLPTAERLTVVVVKA-- 307 +P Q ++ +V EIL+ L Y T RL+ V+K Sbjct: 427 EPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSH 486 Query: 308 -----------------KNLIWTNDKTTADPFVKVYLLQD-GRKMSKKKTAVKRDDPNPV 349 K+LI D +VK+ LL G++MSK KT+++R PNPV Sbjct: 487 FKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSIRRGQPNPV 546 Query: 350 FNEAMIFSVPAIVLQDLSLRVTVAESSSDGRGDNVGHVIIGPSASG-MGTTHWNQMLATL 408 + E +F V L D++L ++V S R + +G + +G ++SG HW +M + Sbjct: 547 YKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESK 606 Query: 409 RRPVSMWHAV 418 + V WHA+ Sbjct: 607 GQQVCRWHAL 616 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.132 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,515,857 Number of Sequences: 37866 Number of extensions: 684623 Number of successful extensions: 2059 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 75 Number of HSP's successfully gapped in prelim test: 54 Number of HSP's that attempted gapping in prelim test: 1762 Number of HSP's gapped (non-prelim): 230 length of query: 421 length of database: 18,247,518 effective HSP length: 105 effective length of query: 316 effective length of database: 14,271,588 effective search space: 4509821808 effective search space used: 4509821808 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.