Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 29294619
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|29294619 sweet taste receptor T1r isoform c [Homo sapiens]
(587 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|29294619 sweet taste receptor T1r isoform c [Homo sapiens] 1224 0.0
gi|29294615 sweet taste receptor T1r isoform b [Homo sapiens] 884 0.0
gi|29294621 sweet taste receptor T1r isoform d [Homo sapiens] 588 e-168
gi|29294617 sweet taste receptor T1r isoform a [Homo sapiens] 345 9e-95
gi|112789566 taste receptor, type 1, member 2 [Homo sapiens] 261 2e-69
gi|91206396 taste receptor, type 1, member 3 [Homo sapiens] 207 3e-53
gi|37577159 calcium-sensing receptor [Homo sapiens] 203 3e-52
gi|112807234 G protein-coupled receptor, family C, group 6, memb... 196 7e-50
gi|166999223 glutamate receptor, metabotropic 1 isoform beta pre... 155 1e-37
gi|166999098 glutamate receptor, metabotropic 1 isoform alpha pr... 155 1e-37
gi|219842343 glutamate receptor, metabotropic 5 isoform a precur... 144 3e-34
gi|4504143 glutamate receptor, metabotropic 5 isoform b precurso... 144 3e-34
gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens] 135 8e-32
gi|46358417 glutamate receptor, metabotropic 3 precursor [Homo s... 124 3e-28
gi|110611176 glutamate receptor, metabotropic 6 precursor [Homo ... 122 9e-28
gi|66529100 glutamate receptor, metabotropic 2 isoform a precurs... 121 2e-27
gi|32528268 glutamate receptor, metabotropic 7 isoform b precurs... 116 5e-26
gi|4504147 glutamate receptor, metabotropic 7 isoform a precurso... 116 5e-26
gi|187960069 glutamate receptor, metabotropic 8 isoform b precur... 114 2e-25
gi|187960067 glutamate receptor, metabotropic 8 isoform a precur... 114 2e-25
gi|194248052 glutamate receptor, metabotropic 2 isoform b [Homo ... 69 2e-11
gi|33356136 hypothetical protein LOC222223 isoform 2 [Homo sapiens] 39 0.010
gi|218505750 hypothetical protein LOC222223 isoform 1 [Homo sapi... 39 0.010
gi|239749596 PREDICTED: hypothetical protein XP_002347099 [Homo ... 39 0.013
gi|239743863 PREDICTED: hypothetical protein XP_002342982 [Homo ... 39 0.013
gi|239755070 PREDICTED: similar to proprotein convertase subtili... 38 0.030
gi|83716019 zinc finger protein 284 [Homo sapiens] 37 0.039
gi|7662424 zinc finger protein 510 [Homo sapiens] 35 0.15
gi|37655173 zinc finger protein 155 [Homo sapiens] 34 0.33
gi|37655171 zinc finger protein 155 [Homo sapiens] 34 0.33
>gi|29294619 sweet taste receptor T1r isoform c [Homo sapiens]
Length = 587
Score = 1224 bits (3166), Expect = 0.0
Identities = 587/587 (100%), Positives = 587/587 (100%)
Query: 1 MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVT 60
MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVT
Sbjct: 1 MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVT 60
Query: 61 LCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLS 120
LCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLS
Sbjct: 61 LCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLS 120
Query: 121 LPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHK 180
LPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHK
Sbjct: 121 LPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHK 180
Query: 181 DTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPK 240
DTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPK
Sbjct: 181 DTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPK 240
Query: 241 SVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFP 300
SVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFP
Sbjct: 241 SVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFP 300
Query: 301 RTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAA 360
RTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAA
Sbjct: 301 RTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAA 360
Query: 361 GSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYHAWV 420
GSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYHAWV
Sbjct: 361 GSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYHAWV 420
Query: 421 QNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLECTETNSLGFILAFLY 480
QNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLECTETNSLGFILAFLY
Sbjct: 421 QNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLECTETNSLGFILAFLY 480
Query: 481 NGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGKYLPAANMM 540
NGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGKYLPAANMM
Sbjct: 481 NGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGKYLPAANMM 540
Query: 541 AGLSSLSSGFGGYFLPKCYVILCRPDLNSTEHFQASIQDYTRRCGST 587
AGLSSLSSGFGGYFLPKCYVILCRPDLNSTEHFQASIQDYTRRCGST
Sbjct: 541 AGLSSLSSGFGGYFLPKCYVILCRPDLNSTEHFQASIQDYTRRCGST 587
>gi|29294615 sweet taste receptor T1r isoform b [Homo sapiens]
Length = 841
Score = 884 bits (2284), Expect = 0.0
Identities = 421/421 (100%), Positives = 421/421 (100%)
Query: 167 LLEQIHKVHFLLHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINE 226
LLEQIHKVHFLLHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINE
Sbjct: 421 LLEQIHKVHFLLHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINE 480
Query: 227 TKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCG 286
TKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCG
Sbjct: 481 TKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCG 540
Query: 287 KEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSA 346
KEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSA
Sbjct: 541 KEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSA 600
Query: 347 GGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIF 406
GGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIF
Sbjct: 601 GGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIF 660
Query: 407 KFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLEC 466
KFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLEC
Sbjct: 661 KFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLEC 720
Query: 467 TETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTA 526
TETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTA
Sbjct: 721 TETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTA 780
Query: 527 SVYDGKYLPAANMMAGLSSLSSGFGGYFLPKCYVILCRPDLNSTEHFQASIQDYTRRCGS 586
SVYDGKYLPAANMMAGLSSLSSGFGGYFLPKCYVILCRPDLNSTEHFQASIQDYTRRCGS
Sbjct: 781 SVYDGKYLPAANMMAGLSSLSSGFGGYFLPKCYVILCRPDLNSTEHFQASIQDYTRRCGS 840
Query: 587 T 587
T
Sbjct: 841 T 841
Score = 345 bits (884), Expect = 9e-95
Identities = 166/167 (99%), Positives = 167/167 (100%)
Query: 1 MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVT 60
MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVT
Sbjct: 1 MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVT 60
Query: 61 LCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLS 120
LCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLS
Sbjct: 61 LCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLS 120
Query: 121 LPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPML 167
LPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPM+
Sbjct: 121 LPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMI 167
>gi|29294621 sweet taste receptor T1r isoform d [Homo sapiens]
Length = 324
Score = 588 bits (1516), Expect = e-168
Identities = 277/277 (100%), Positives = 277/277 (100%)
Query: 1 MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVT 60
MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVT
Sbjct: 1 MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVT 60
Query: 61 LCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLS 120
LCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLS
Sbjct: 61 LCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLS 120
Query: 121 LPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHK 180
LPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHK
Sbjct: 121 LPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMLLEQIHKVHFLLHK 180
Query: 181 DTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPK 240
DTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPK
Sbjct: 181 DTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPK 240
Query: 241 SVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKS 277
SVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKS
Sbjct: 241 SVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKS 277
>gi|29294617 sweet taste receptor T1r isoform a [Homo sapiens]
Length = 480
Score = 345 bits (884), Expect = 9e-95
Identities = 166/167 (99%), Positives = 167/167 (100%)
Query: 1 MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVT 60
MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVT
Sbjct: 1 MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVT 60
Query: 61 LCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLS 120
LCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLS
Sbjct: 61 LCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLS 120
Query: 121 LPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPML 167
LPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPM+
Sbjct: 121 LPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMI 167
>gi|112789566 taste receptor, type 1, member 2 [Homo sapiens]
Length = 839
Score = 261 bits (666), Expect = 2e-69
Identities = 148/420 (35%), Positives = 220/420 (52%), Gaps = 5/420 (1%)
Query: 167 LLEQIHKVHFLLHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNI-N 225
LLE+I KV+F L + F+ D I+ W W+ + F + S + P+Q + N
Sbjct: 420 LLEEIWKVNFTLLDHQIFFDPQGDVALHLEIVQWQWDRSQNPFQSVAS--YYPLQRQLKN 477
Query: 226 ETKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKS-DLYRCQP 284
I WH +N +P S+CS C G ++ G H CCFEC+ C GTFLN + D Y CQ
Sbjct: 478 IQDISWHTINNTIPMSMCSKRCQSGQKKKPVGIHVCCFECIDCLPGTFLNHTEDEYECQA 537
Query: 285 CGKEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVR 344
C EW+ + +CF R +VFL E + + L L L +F H TP+VR
Sbjct: 538 CPNNEWSYQSETSCFKRQLVFLEWHEAPTIAVALLAALGFLSTLAILVIFWRHFQTPIVR 597
Query: 345 SAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLII 404
SAGG +CFLML L + + G P CL RQALF L FTI +SC+ VRSFQ++
Sbjct: 598 SAGGPMCFLMLTLLLVAYMVVPVYVGPPKVSTCLCRQALFPLCFTICISCIAVRSFQIVC 657
Query: 405 IFKFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLP-AREYQRFPHLVM 463
FK +++ P Y WV+ G + + + +++I + ++ P R P + +
Sbjct: 658 AFKMASRFPRAYSYWVRYQGPYVSMAFITVLKMVIVVIGMLATGLSPTTRTDPDDPKITI 717
Query: 464 LECTETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFF 523
+ C + + LLS+ F+ +Y+GK+LP NYNEAK +T S+ F F S ++
Sbjct: 718 VSCNPNYRNSLLFNTSLDLLLSVVGFSFAYMGKELPTNYNEAKFITLSMTFYFTSSVSLC 777
Query: 524 TTASVYDGKYLPAANMMAGLSSLSSGFGGYFLPKCYVILCRPDLNSTEHFQASIQDYTRR 583
T S Y G + +++ + +L + GYF PKCY+IL P+ N+ +F + IQ YT R
Sbjct: 778 TFMSAYSGVLVTIVDLLVTVLNLLAISLGYFGPKCYMILFYPERNTPAYFNSMIQGYTMR 837
Score = 106 bits (265), Expect = 5e-23
Identities = 72/195 (36%), Positives = 100/195 (51%), Gaps = 13/195 (6%)
Query: 31 DFTLPGDYLLAGLFPLHSGCLQVRHRP--EVTLCDRSCSFNEHGYHLFQAMRLGVEEINN 88
DF LPGDYLL GLF LH+ + H +V +C + GY+L QAMR VEEINN
Sbjct: 26 DFYLPGDYLLGGLFSLHANMKGIVHLNFLQVPMC-KEYEVKVIGYNLMQAMRFAVEEINN 84
Query: 89 STALLPNITLGYQLYDVCSDSANVYATLRVLSLPGQHHIELQGDLLHYSPTVLAVIGPDS 148
++LLP + LGY++ DVC S NV L L+ + + +Q D +Y V+AVIGPD+
Sbjct: 85 DSSLLPGVLLGYEIVDVCYISNNVQPVLYFLA-HEDNLLPIQEDYSNYISRVVAVIGPDN 143
Query: 149 TNRAATTAALLSPFLVPMLL------EQIHKVHFLLHKDTVAFNDNRDPLSSYNIIAWDW 202
+ T A LS FL+P + E KV F T D+ ++ + W
Sbjct: 144 SESVMTVANFLSLFLLPQITYSAISDELRDKVRFPALLRTTPSADHHIEAMVQLMLHFRW 203
Query: 203 NGPKWTFTVLGSSTW 217
N W ++ S T+
Sbjct: 204 N---WIIVLVSSDTY 215
>gi|91206396 taste receptor, type 1, member 3 [Homo sapiens]
Length = 852
Score = 207 bits (526), Expect = 3e-53
Identities = 125/407 (30%), Positives = 200/407 (49%), Gaps = 3/407 (0%)
Query: 167 LLEQIHKVHFLLHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINE 226
LLE ++ + F + + F+ + + Y++ W W G +G S L
Sbjct: 426 LLENMYNLTFHVGGLPLRFDSSGNVDMEYDLKLWVWQGSVPRLHDVGRFNGS---LRTER 482
Query: 227 TKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCG 286
KI+WH DNQ P S CS C EG R V GFH CC++CV C AG++ D C CG
Sbjct: 483 LKIRWHTSDNQKPVSRCSRQCQEGQVRRVKGFHSCCYDCVDCEAGSYRQNPDDIACTFCG 542
Query: 287 KEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSA 346
++EW+PE S CF R FLA E +LL +L L L+L GLF H D+P+V+++
Sbjct: 543 QDEWSPERSTRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPLVQAS 602
Query: 347 GGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIF 406
GG L L L S+ F G+P+ CL +Q L L T LS L +++ ++ +
Sbjct: 603 GGPLACFGLVCLGLVCLSVLLFPGQPSPARCLAQQPLSHLPLTGCLSTLFLQAAEIFVES 662
Query: 407 KFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLEC 466
+ ++ A L V+++ ++ +C +LV + P ++ P ++ C
Sbjct: 663 ELPLSWADRLSGCLRGPWAWLVVLLAMLVEVALCTWYLVAFPPEVVTDWHMLPTEALVHC 722
Query: 467 TETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTA 526
+ + F LA N L+ F ++L + P YN A+ +TF++L F++W++F
Sbjct: 723 RTRSWVSFGLAHATNATLAFLCFLGTFLVRSQPGRYNRARGLTFAMLAYFITWVSFVPLL 782
Query: 527 SVYDGKYLPAANMMAGLSSLSSGFGGYFLPKCYVILCRPDLNSTEHF 573
+ PA M A L + + LP+CY+++ +P LN+ E F
Sbjct: 783 ANVQVVLRPAVQMGALLLCVLGILAAFHLPRCYLLMRQPGLNTPEFF 829
Score = 90.5 bits (223), Expect = 4e-18
Identities = 56/143 (39%), Positives = 75/143 (52%), Gaps = 7/143 (4%)
Query: 29 SPDFTLPGDYLLAGLFPL---HSGCLQVRHRPEVTLCDRSCSFNEHGYHLFQAMRLGVEE 85
S + GDY+L GLFPL L+ R RP +C R F+ +G AM++ VEE
Sbjct: 26 SQQLRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTR---FSSNGLLWALAMKMAVEE 82
Query: 86 INNSTALLPNITLGYQLYDVCSDS-ANVYATLRVLSLPGQHHIELQGDLLHYSPTVLAVI 144
INN + LLP + LGY L+D CS+ + +L L+ G I + Y P VLAVI
Sbjct: 83 INNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDIAAYCNYTQYQPRVLAVI 142
Query: 145 GPDSTNRAATTAALLSPFLVPML 167
GP S+ A T S FL+P +
Sbjct: 143 GPHSSELAMVTGKFFSFFLMPQV 165
>gi|37577159 calcium-sensing receptor [Homo sapiens]
Length = 1078
Score = 203 bits (517), Expect = 3e-52
Identities = 123/405 (30%), Positives = 205/405 (50%), Gaps = 13/405 (3%)
Query: 181 DTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPV-----QLNINETKIQWHGKD 235
+ V F++ D + +Y+II W + + ++ +L INE KI W G
Sbjct: 475 EQVTFDECGDLVGNYSIINWHLSPEDGSIVFKEVGYYNVYAKKGERLFINEEKILWSGFS 534
Query: 236 NQVPKSVCSSDCLEGHQR-VVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEG 294
+VP S CS DCL G ++ ++ G CCFECV C G + +++D C C + W+ E
Sbjct: 535 REVPFSNCSRDCLAGTRKGIIEGEPTCCFECVECPDGEYSDETDASACNKCPDDFWSNEN 594
Query: 295 SQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLM 354
+C + + FL+ E L L + L G+F +TP+V++ L +L+
Sbjct: 595 HTSCIAKEIEFLSWTEPFGIALTLFAVLGIFLTAFVLGVFIKFRNTPIVKATNRELSYLL 654
Query: 355 LGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPT 414
L SL S F GEP C LRQ F + F + +SC+ V++ +++++F+ K+PT
Sbjct: 655 LFSLLCCFSSSLFFIGEPQDWTCRLRQPAFGISFVLCISCILVKTNRVLLVFE--AKIPT 712
Query: 415 FYH-AWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLECTETN--S 471
+H W + L V + + Q++IC+ WL P R + ++ + C E + +
Sbjct: 713 SFHRKWWGLNLQFLLVFLCTFMQIVICVIWLYTAPPSSYRNQELEDEIIFITCHEGSLMA 772
Query: 472 LGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDG 531
LGF++ Y LL+ F ++ + LPEN+NEAK +TFS+L F+ WI+F + G
Sbjct: 773 LGFLIG--YTCLLAAICFFFAFKSRKLPENFNEAKFITFSMLIFFIVWISFIPAYASTYG 830
Query: 532 KYLPAANMMAGLSSLSSGFGGYFLPKCYVILCRPDLNSTEHFQAS 576
K++ A ++A L++ F K Y+IL +P N+ E + S
Sbjct: 831 KFVSAVEVIAILAASFGLLACIFFNKIYIILFKPSRNTIEEVRCS 875
Score = 88.6 bits (218), Expect = 1e-17
Identities = 57/166 (34%), Positives = 84/166 (50%), Gaps = 19/166 (11%)
Query: 16 SCCW---AFACHSTESSPDFTLP--GDYLLAGLFPLHSGCL----QVRHRPEVTLCDRSC 66
SCCW A H++ PD GD +L GLFP+H G ++ RPE C R
Sbjct: 5 SCCWVLLALTWHTSAYGPDQRAQKKGDIILGGLFPIHFGVAAKDQDLKSRPESVECIR-- 62
Query: 67 SFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLSLPGQHH 126
+N G+ QAM +EEIN+S ALLPN+TLGY+++D C+ + A LS Q+
Sbjct: 63 -YNFRGFRWLQAMIFAIEEINSSPALLPNLTLGYRIFDTCNTVSK--ALEATLSFVAQNK 119
Query: 127 IELQG-----DLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPML 167
I+ + + P+ +AV+G + + A LL F +P +
Sbjct: 120 IDSLNLDEFCNCSEHIPSTIAVVGATGSGVSTAVANLLGLFYIPQV 165
>gi|112807234 G protein-coupled receptor, family C, group 6, member
A [Homo sapiens]
Length = 926
Score = 196 bits (497), Expect = 7e-50
Identities = 122/418 (29%), Positives = 204/418 (48%), Gaps = 9/418 (2%)
Query: 167 LLEQIHKVHFLLHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINE 226
LL + V F ++ F+ + D + Y+++ W T T + I +
Sbjct: 446 LLGVLKNVTFTDGWNSFHFDAHGDLNTGYDVVLWKEINGHMTVTKMAEYDLQNDVFIIPD 505
Query: 227 TKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHH-CCFECVPCGAGTFLNKSDLYRCQPC 285
+ + ++ + +S CS +C G + T H CC+EC C + N++D+ C C
Sbjct: 506 QETKNEFRNLKQIQSKCSKECSPGQMKKTTRSQHICCYECQNCPENHYTNQTDMPHCLLC 565
Query: 286 G-KEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVR 344
K WAP S CF + V +L + + +LL + L ++ +L +F +L+TPVV+
Sbjct: 566 NNKTHWAPVRSTMCFEKEVEYLNWNDSLAILLLILSLLGIIFVLVVGIIFTRNLNTPVVK 625
Query: 345 SAGG-RLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLI 403
S+GG R+C+++L S F GEP C RQ +F + FT+ +SC+ +S +++
Sbjct: 626 SSGGLRVCYVILLCHFLNFASTSFFIGEPQDFTCKTRQTMFGVSFTLCISCILTKSLKIL 685
Query: 404 IIFKFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVM 463
+ F F K+ F + L + + Q++IC WL+ P P +++
Sbjct: 686 LAFSFDPKLQKFLKCLYRPI---LIIFTCTGIQVVICTLWLIFAAPTVEVNVS-LPRVII 741
Query: 464 LECTETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFF 523
LEC E + L F Y +L+ F ++ GK ENYNEAK +TF +L F++WI F
Sbjct: 742 LECEEGSILAFGTMLGYIAILAFICFIFAFKGKY--ENYNEAKFITFGMLIYFIAWITFI 799
Query: 524 TTASVYDGKYLPAANMMAGLSSLSSGFGGYFLPKCYVILCRPDLNSTEHFQASIQDYT 581
+ GKY+PA ++ L S F+PKCYVI+C+ ++N+ F I Y+
Sbjct: 800 PIYATTFGKYVPAVEIIVILISNYGILYCTFIPKCYVIICKQEINTKSAFLKMIYSYS 857
Score = 65.5 bits (158), Expect = 1e-10
Identities = 46/148 (31%), Positives = 69/148 (46%), Gaps = 4/148 (2%)
Query: 23 CHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVTLCDRSCSFNEHGYHLFQAMRLG 82
C + + T PG ++ GLF +H L P F + AM
Sbjct: 21 CQTPDDFVAATSPGHIIIGGLFAIHEKMLSSEDSPRRPQIQECVGFEISVFLQTLAMIHS 80
Query: 83 VEEINNSTALLPNITLGYQLYDVCSD-SANVYATLRVLSL--PGQHHIELQGDLLHYSPT 139
+E INNST LLP + LGY++YD C++ + + ATLR LS + +E + D Y P
Sbjct: 81 IEMINNST-LLPGVKLGYEIYDTCTEVTVAMAATLRFLSKFNCSRETVEFKCDYSSYMPR 139
Query: 140 VLAVIGPDSTNRAATTAALLSPFLVPML 167
V AVIG + + +L+ L+P +
Sbjct: 140 VKAVIGSGYSEITMAVSRMLNLQLMPQV 167
>gi|166999223 glutamate receptor, metabotropic 1 isoform beta
precursor [Homo sapiens]
Length = 906
Score = 155 bits (392), Expect = 1e-37
Identities = 113/419 (26%), Positives = 199/419 (47%), Gaps = 24/419 (5%)
Query: 167 LLEQIHKVHFL-LHKDTVAFNDNRDPLSSYNIIAWDWN-GPKWTFTVLGSSTWSPVQLNI 224
LL+ + K F+ + + V F++ D Y+I+ + ++ + +G TW LNI
Sbjct: 450 LLDFLIKSSFIGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVG--TWHEGVLNI 507
Query: 225 NETKIQWHGKDNQVPKSVCSSDCLEGHQRVVT-GFHHCCFECVPCGAGTFLNKSDLYRCQ 283
++ KIQ + + V +SVCS CL+G +V+ G CC+ C C ++ D + C+
Sbjct: 508 DDYKIQMN--KSGVVRSVCSEPCLKGQIKVIRKGEVSCCWICTACKENEYVQ--DEFTCK 563
Query: 284 PCGKEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVV 343
C W C P V +L S + +A + L +L+ L +F + DTPVV
Sbjct: 564 ACDLGWWPNADLTGCEPIPVRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVV 623
Query: 344 RSAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLI 403
+S+ LC+++L + G + +PT +C L++ L L + S L ++ ++
Sbjct: 624 KSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIA 683
Query: 404 IIF-----KFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRF 458
I K T+ P F AW Q A + + + QL + +T +++ P+P Y
Sbjct: 684 RILAGSKKKICTRKPRFMSAWAQVIIASILISV----QLTLVVTLIIMEPPMPILSYPSI 739
Query: 459 PHLVMLECTETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVS 518
+ ++ T++LG + YNGLL +S ++ +++P N+NEAK + F++ +
Sbjct: 740 KEVYLI--CNTSNLGVVAPLGYNGLLIMSCTYYAFKTRNVPANFNEAKYIAFTMYTTCII 797
Query: 519 WIAFFTTASVYDG-KYLPAANMMAGLSSLSSGFGGYFLPKCYVILCRPDLNSTEHFQAS 576
W+AF +Y G Y A S++ G F PK Y+I+ +P+ N F S
Sbjct: 798 WLAF---VPIYFGSNYKIITTCFAVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTS 853
Score = 39.7 bits (91), Expect = 0.008
Identities = 40/150 (26%), Positives = 66/150 (44%), Gaps = 23/150 (15%)
Query: 34 LPGDYLLAGLFPLHSGCLQVRHRPEVT-LCDRSCSF--NEHGYHLFQAMRLGVEEINNST 90
+ GD ++ LF +H H+P + +R C ++G +AM +++IN
Sbjct: 41 MDGDVIIGALFSVH-------HQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADP 93
Query: 91 ALLPNITLGYQLYDVCSDSANV------YATLRVLSL----PGQHHIELQGDLLHYSPT- 139
LLPNITLG ++ D C S+ + ++S+ G + G L T
Sbjct: 94 VLLPNITLGSEIRDSCWHSSVALEQSIEFIRDSLISIRDEKDGINRCLPDGQSLPPGRTK 153
Query: 140 --VLAVIGPDSTNRAATTAALLSPFLVPML 167
+ VIGP S++ A LL F +P +
Sbjct: 154 KPIAGVIGPGSSSVAIQVQNLLQLFDIPQI 183
>gi|166999098 glutamate receptor, metabotropic 1 isoform alpha
precursor [Homo sapiens]
Length = 1194
Score = 155 bits (392), Expect = 1e-37
Identities = 113/419 (26%), Positives = 199/419 (47%), Gaps = 24/419 (5%)
Query: 167 LLEQIHKVHFL-LHKDTVAFNDNRDPLSSYNIIAWDWN-GPKWTFTVLGSSTWSPVQLNI 224
LL+ + K F+ + + V F++ D Y+I+ + ++ + +G TW LNI
Sbjct: 450 LLDFLIKSSFIGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVG--TWHEGVLNI 507
Query: 225 NETKIQWHGKDNQVPKSVCSSDCLEGHQRVVT-GFHHCCFECVPCGAGTFLNKSDLYRCQ 283
++ KIQ + + V +SVCS CL+G +V+ G CC+ C C ++ D + C+
Sbjct: 508 DDYKIQMN--KSGVVRSVCSEPCLKGQIKVIRKGEVSCCWICTACKENEYVQ--DEFTCK 563
Query: 284 PCGKEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVV 343
C W C P V +L S + +A + L +L+ L +F + DTPVV
Sbjct: 564 ACDLGWWPNADLTGCEPIPVRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVV 623
Query: 344 RSAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLI 403
+S+ LC+++L + G + +PT +C L++ L L + S L ++ ++
Sbjct: 624 KSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIA 683
Query: 404 IIF-----KFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRF 458
I K T+ P F AW Q A + + + QL + +T +++ P+P Y
Sbjct: 684 RILAGSKKKICTRKPRFMSAWAQVIIASILISV----QLTLVVTLIIMEPPMPILSYPSI 739
Query: 459 PHLVMLECTETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVS 518
+ ++ T++LG + YNGLL +S ++ +++P N+NEAK + F++ +
Sbjct: 740 KEVYLI--CNTSNLGVVAPLGYNGLLIMSCTYYAFKTRNVPANFNEAKYIAFTMYTTCII 797
Query: 519 WIAFFTTASVYDG-KYLPAANMMAGLSSLSSGFGGYFLPKCYVILCRPDLNSTEHFQAS 576
W+AF +Y G Y A S++ G F PK Y+I+ +P+ N F S
Sbjct: 798 WLAF---VPIYFGSNYKIITTCFAVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTS 853
Score = 39.7 bits (91), Expect = 0.008
Identities = 40/150 (26%), Positives = 66/150 (44%), Gaps = 23/150 (15%)
Query: 34 LPGDYLLAGLFPLHSGCLQVRHRPEVT-LCDRSCSF--NEHGYHLFQAMRLGVEEINNST 90
+ GD ++ LF +H H+P + +R C ++G +AM +++IN
Sbjct: 41 MDGDVIIGALFSVH-------HQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADP 93
Query: 91 ALLPNITLGYQLYDVCSDSANV------YATLRVLSL----PGQHHIELQGDLLHYSPT- 139
LLPNITLG ++ D C S+ + ++S+ G + G L T
Sbjct: 94 VLLPNITLGSEIRDSCWHSSVALEQSIEFIRDSLISIRDEKDGINRCLPDGQSLPPGRTK 153
Query: 140 --VLAVIGPDSTNRAATTAALLSPFLVPML 167
+ VIGP S++ A LL F +P +
Sbjct: 154 KPIAGVIGPGSSSVAIQVQNLLQLFDIPQI 183
>gi|219842343 glutamate receptor, metabotropic 5 isoform a precursor
[Homo sapiens]
Length = 1212
Score = 144 bits (362), Expect = 3e-34
Identities = 113/418 (27%), Positives = 190/418 (45%), Gaps = 22/418 (5%)
Query: 167 LLEQIHKVHFL-LHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNIN 225
LLE + K +F + DT+ F++N D Y I+ + G + F + +W +L ++
Sbjct: 437 LLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDY-FDYINVGSWDNGELKMD 495
Query: 226 ETKIQWHGKDNQVPKSVCSSDCLEGHQRVVT-GFHHCCFECVPCGAGTFLNKSDLYRCQP 284
+ ++ W K N + +SVCS C +G +V+ G CC+ C PC ++ D Y C+
Sbjct: 496 DDEV-WSKKSNII-RSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYV--FDEYTCKA 551
Query: 285 CGKEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVR 344
C W + C V +L + + L LL L +F + DTPVV+
Sbjct: 552 CQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVK 611
Query: 345 SAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLII 404
S+ LC+++L + G + +P + C L++ L + S L ++ ++
Sbjct: 612 SSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIAR 671
Query: 405 IF-----KFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFP 459
I K TK P F A Q A + + I QL I + ++ P +Y
Sbjct: 672 ILAGSKKKICTKKPRFMSACAQLVIAFILICI----QLGIIVALFIMEPPDIMHDYPSIR 727
Query: 460 HLVMLECTETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSW 519
+ ++ C TN LG + YNGLL +S ++ +++P N+NEAK + F++ + W
Sbjct: 728 EVYLI-CNTTN-LGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIW 785
Query: 520 IAFFTTASVYDGKYLPAANMMAGLS-SLSSGFGGYFLPKCYVILCRPDLNSTEHFQAS 576
+AF +Y G M +S S + G F+PK Y+IL +P+ N F S
Sbjct: 786 LAF---VPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTS 840
Score = 50.1 bits (118), Expect = 6e-06
Identities = 40/147 (27%), Positives = 65/147 (44%), Gaps = 20/147 (13%)
Query: 34 LPGDYLLAGLFPLHSGCLQVRHRPEVT-LCDRSCSF--NEHGYHLFQAMRLGVEEINNST 90
+PGD ++ LF +H H+P V + +R C ++G +AM +E IN+
Sbjct: 31 MPGDIIIGALFSVH-------HQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDP 83
Query: 91 ALLPNITLGYQLYDVCSDSA----NVYATLRVLSLPGQHH------IELQGDLLHYSPTV 140
LLPNITLG ++ D C SA +R + + ++ +
Sbjct: 84 TLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPI 143
Query: 141 LAVIGPDSTNRAATTAALLSPFLVPML 167
+ VIGP S++ A LL F +P +
Sbjct: 144 VGVIGPGSSSVAIQVQNLLQLFNIPQI 170
>gi|4504143 glutamate receptor, metabotropic 5 isoform b precursor
[Homo sapiens]
Length = 1180
Score = 144 bits (362), Expect = 3e-34
Identities = 113/418 (27%), Positives = 190/418 (45%), Gaps = 22/418 (5%)
Query: 167 LLEQIHKVHFL-LHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNIN 225
LLE + K +F + DT+ F++N D Y I+ + G + F + +W +L ++
Sbjct: 437 LLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDY-FDYINVGSWDNGELKMD 495
Query: 226 ETKIQWHGKDNQVPKSVCSSDCLEGHQRVVT-GFHHCCFECVPCGAGTFLNKSDLYRCQP 284
+ ++ W K N + +SVCS C +G +V+ G CC+ C PC ++ D Y C+
Sbjct: 496 DDEV-WSKKSNII-RSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYV--FDEYTCKA 551
Query: 285 CGKEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVR 344
C W + C V +L + + L LL L +F + DTPVV+
Sbjct: 552 CQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVK 611
Query: 345 SAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLII 404
S+ LC+++L + G + +P + C L++ L + S L ++ ++
Sbjct: 612 SSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSALVTKTNRIAR 671
Query: 405 IF-----KFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFP 459
I K TK P F A Q A + + I QL I + ++ P +Y
Sbjct: 672 ILAGSKKKICTKKPRFMSACAQLVIAFILICI----QLGIIVALFIMEPPDIMHDYPSIR 727
Query: 460 HLVMLECTETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSW 519
+ ++ C TN LG + YNGLL +S ++ +++P N+NEAK + F++ + W
Sbjct: 728 EVYLI-CNTTN-LGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIW 785
Query: 520 IAFFTTASVYDGKYLPAANMMAGLS-SLSSGFGGYFLPKCYVILCRPDLNSTEHFQAS 576
+AF +Y G M +S S + G F+PK Y+IL +P+ N F S
Sbjct: 786 LAF---VPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTS 840
Score = 50.1 bits (118), Expect = 6e-06
Identities = 40/147 (27%), Positives = 65/147 (44%), Gaps = 20/147 (13%)
Query: 34 LPGDYLLAGLFPLHSGCLQVRHRPEVT-LCDRSCSF--NEHGYHLFQAMRLGVEEINNST 90
+PGD ++ LF +H H+P V + +R C ++G +AM +E IN+
Sbjct: 31 MPGDIIIGALFSVH-------HQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDP 83
Query: 91 ALLPNITLGYQLYDVCSDSA----NVYATLRVLSLPGQHH------IELQGDLLHYSPTV 140
LLPNITLG ++ D C SA +R + + ++ +
Sbjct: 84 TLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPI 143
Query: 141 LAVIGPDSTNRAATTAALLSPFLVPML 167
+ VIGP S++ A LL F +P +
Sbjct: 144 VGVIGPGSSSVAIQVQNLLQLFNIPQI 170
>gi|4504141 glutamate receptor, metabotropic 4 [Homo sapiens]
Length = 912
Score = 135 bits (341), Expect = 8e-32
Identities = 115/424 (27%), Positives = 189/424 (44%), Gaps = 39/424 (9%)
Query: 167 LLEQIHKVHFL-LHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNIN 225
LL+ I V+F + + V FN+N D Y+I + + V+GS W+ L++
Sbjct: 446 LLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNDSAEYKVIGS--WTD-HLHLR 502
Query: 226 ETKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPC 285
++ W G Q+P+S+CS C G ++ CC+ C PC + + D Y C+ C
Sbjct: 503 IERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCTG--YQYQVDRYTCKTC 560
Query: 286 GKEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAG------LFAWHLD 339
+ E C R + + L + W +L L L ++G A F + D
Sbjct: 561 PYDMRPTENRTGC--RPIPIIKLEWGSPWAVLP----LFLAVVGIAATLFVVITFVRYND 614
Query: 340 TPVVRSAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRS 399
TP+V+++G L +++L + + + EP C LR+ LG +I + L ++
Sbjct: 615 TPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKT 674
Query: 400 FQLIIIF---KFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQ 456
++ IF K S P F Q A F +IS QLL W VV ++Q
Sbjct: 675 NRIYRIFEQGKRSVSAPRFISPASQL--AITFSLIS--LQLLGICVWFVVDPSHSVVDFQ 730
Query: 457 -------RFPHLVMLECTETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVT 509
RF V L+C + + L I Y+ LL ++ + + +PE +NEAK +
Sbjct: 731 DQRTLDPRFARGV-LKC-DISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIG 788
Query: 510 FSLLFNFVSWIA----FFTTASVYDGKYLPAANMMAGLS-SLSSGFGGYFLPKCYVILCR 564
F++ + W+A FF T+ D Y+ + +S S S G ++PK Y+IL
Sbjct: 789 FTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFH 848
Query: 565 PDLN 568
P+ N
Sbjct: 849 PEQN 852
Score = 51.6 bits (122), Expect = 2e-06
Identities = 42/144 (29%), Positives = 65/144 (45%), Gaps = 21/144 (14%)
Query: 34 LPGDYLLAGLFPLHSGCLQVRHRPEVTLCDRSCSFNEHGYHLFQAMRLGVEEINNSTALL 93
+ GD L GLFP+H + + E+ E G H +AM ++ INN LL
Sbjct: 45 IDGDITLGGLFPVHGRGSEGKPCGELK--------KEKGIHRLEAMLFALDRINNDPDLL 96
Query: 94 PNITLGYQLYDVCSDSANVYATLRVLSLPGQHHIELQG----------DLLHYSPTVLAV 143
PNITLG ++ D C S + +A + L+ Q IE G ++ V+ V
Sbjct: 97 PNITLGARILDTC--SRDTHALEQSLTFV-QALIEKDGTEVRCGSGGPPIITKPERVVGV 153
Query: 144 IGPDSTNRAATTAALLSPFLVPML 167
IG ++ + A +L F +P +
Sbjct: 154 IGASGSSVSIMVANILRLFKIPQI 177
>gi|46358417 glutamate receptor, metabotropic 3 precursor [Homo
sapiens]
Length = 879
Score = 124 bits (310), Expect = 3e-28
Identities = 107/433 (24%), Positives = 185/433 (42%), Gaps = 52/433 (12%)
Query: 169 EQIHKVHFLLHKDTVAFNDNRDP------------LSSYNIIAWDWNGPKWTFTVLGSST 216
++++K + L T FN N+D + YN+ + G K+++ +G
Sbjct: 428 KKLYKDYLLKINFTAPFNPNKDADSIVKFDTFGDGMGRYNVFNFQNVGGKYSYLKVGH-- 485
Query: 217 WSPVQLNINETKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNK 276
W+ L+++ I W N VP S CS C + + CC+ C+PC +L
Sbjct: 486 WAET-LSLDVNSIHW--SRNSVPTSQCSDPCAPNEMKNMQPGDVCCWICIPCEPYEYL-- 540
Query: 277 SDLYRCQPCGKEEWAPEGSQTCFPRTVVFLALREHTSWVL--LAANTLLLLLLLGTAGLF 334
+D + C CG +W C+ ++ R +W + + L + +F
Sbjct: 541 ADEFTCMDCGSGQWPTADLTGCYDLPEDYI--RWEDAWAIGPVTIACLGFMCTCMVVTVF 598
Query: 335 AWHLDTPVVRSAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSC 394
H +TP+V+++G LC+++L + + F +P+ C LR+ F I S
Sbjct: 599 IKHNNTPLVKASGRELCYILLFGVGLSYCMTFFFIAKPSPVICALRRLGLGSSFAICYSA 658
Query: 395 LTVRSFQLIIIFKFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLV-------VW 447
L ++ + IF V+N GA IS ++Q+ ICL ++ VW
Sbjct: 659 LLTKTNCIARIFD-----------GVKN-GAQRPKFISPSSQVFICLGLILVQIVMVSVW 706
Query: 448 TPLPAREYQRFP-----HLVMLECTETNSLGFILAFLYNGLLSISAFACSYLGKDLPENY 502
L A +R+ V+L+C +S +++ Y+ +L I ++ + PEN+
Sbjct: 707 LILEAPGTRRYTLAEKRETVILKCNVKDS-SMLISLTYDVILVILCTVYAFKTRKCPENF 765
Query: 503 NEAKCVTFSLLFNFVSWIAFFTTASVYDGKYLPAANMMAGLSSLSSGF---GGYFLPKCY 559
NEAK + F++ + W+AF V Y M +S SGF G F PK +
Sbjct: 766 NEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMC-ISVSLSGFVVLGCLFAPKVH 824
Query: 560 VILCRPDLNSTEH 572
+IL +P N H
Sbjct: 825 IILFQPQKNVVTH 837
Score = 40.4 bits (93), Expect = 0.005
Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 10/78 (12%)
Query: 31 DFTLPGDYLLAGLFPLHSGCLQVRHRPEVTLCDRSCSFNE-HGYHLFQAMRLGVEEINNS 89
+ + GD +L GLFP++ + T + NE G +AM ++EIN
Sbjct: 32 EIKIEGDLVLGGLFPINE---------KGTGTEECGRINEDRGIQRLEAMLFAIDEINKD 82
Query: 90 TALLPNITLGYQLYDVCS 107
LLP + LG + D CS
Sbjct: 83 DYLLPGVKLGVHILDTCS 100
>gi|110611176 glutamate receptor, metabotropic 6 precursor [Homo
sapiens]
Length = 877
Score = 122 bits (306), Expect = 9e-28
Identities = 114/426 (26%), Positives = 182/426 (42%), Gaps = 38/426 (8%)
Query: 166 MLLEQIHKVHFLLHKDT-VAFNDNRDPLSSYNIIAWD-WNGPKWTFTVLGSSTWSPVQLN 223
MLL+ I V F T V FN+N D Y+I + NG + W+ L
Sbjct: 440 MLLQYIRAVRFNGSAGTPVMFNENGDAPGRYDIFQYQATNGSASSGGYQAVGQWAET-LR 498
Query: 224 INETKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQ 283
++ +QW G ++VP S+CS C G ++ + CC+ C C F + D + C+
Sbjct: 499 LDVEALQWSGDPHEVPSSLCSLPCGPGERKKMVKGVPCCWHCEACDGYRF--QVDEFTCE 556
Query: 284 PCGKEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLG------TAGLFAWH 337
C + C P VV L SW A LLL +LG F +
Sbjct: 557 ACPGDMRPTPNHTGCRPTPVVRL------SWSSPWAAPPLLLAVLGIVATTTVVATFVRY 610
Query: 338 LDTPVVRSAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTV 397
+TP+VR++G L +++L + + EP C R+ LG T+ S L
Sbjct: 611 NNTPIVRASGRELSYVLLTGIFLIYAITFLMVAEPGAAVCAARRLFLGLGTTLSYSALLT 670
Query: 398 RSFQLIIIF---KFSTKVPTFYHAWVQNHGAGLFVMIS-SAAQLLICLTWLVVWTPLPAR 453
++ ++ IF K S P F Q L + S ++ Q++ + WL P
Sbjct: 671 KTNRIYRIFEQGKRSVTPPPFISPTSQ-----LVITFSLTSLQVVGMIAWLGARPPHSVI 725
Query: 454 EYQRFPHL------VMLECTETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKC 507
+Y+ + +L+C + + L I Y+ LL ++ + + +PE +NEAK
Sbjct: 726 DYEEQRTVDPEQARGVLKC-DMSDLSLIGCLGYSLLLMVTCTVYAIKARGVPETFNEAKP 784
Query: 508 VTFSLLFNFVSWIA----FFTTASVYDGKYLPAANMMAGLS-SLSSGFGGYFLPKCYVIL 562
+ F++ + W+A FF TA + Y+ + LS S S G ++PK YVIL
Sbjct: 785 IGFTMYTTCIIWLAFVPIFFGTAQSAEKIYIQTTTLTVSLSLSASVSLGMLYVPKTYVIL 844
Query: 563 CRPDLN 568
P+ N
Sbjct: 845 FHPEQN 850
Score = 47.4 bits (111), Expect = 4e-05
Identities = 46/174 (26%), Positives = 71/174 (40%), Gaps = 30/174 (17%)
Query: 11 LQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVTLCDRSCSF-- 68
L L+ W ++ L G L GLFP+H+ R+C
Sbjct: 12 LVALLPLAWLAQAGLARAAGSVRLAGGLTLGGLFPVHAR----------GAAGRACGQLK 61
Query: 69 NEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLSLPGQHHIE 128
E G H +AM ++ +N LLP + LG +L D C S + YA + LS Q I
Sbjct: 62 KEQGVHRLEAMLYALDRVNADPELLPGVRLGARLLDTC--SRDTYALEQALSFV-QALIR 118
Query: 129 LQGD-------------LLHYSP--TVLAVIGPDSTNRAATTAALLSPFLVPML 167
+GD L +P V+AV+G +++ + A +L F +P +
Sbjct: 119 GRGDGDEVGVRCPGGVPPLRPAPPERVVAVVGASASSVSIMVANVLRLFAIPQI 172
>gi|66529100 glutamate receptor, metabotropic 2 isoform a precursor
[Homo sapiens]
Length = 872
Score = 121 bits (304), Expect = 2e-27
Identities = 106/400 (26%), Positives = 170/400 (42%), Gaps = 22/400 (5%)
Query: 183 VAFNDNRDPLSSYNIIAWDWNGP-KWTFTVLGSSTWSPVQLNINETKIQWHGKD-NQVPK 240
V F+ D + YNI + G ++ + +G W+ L ++ + I W +P
Sbjct: 441 VRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGY--WAE-GLTLDTSLIPWASPSAGPLPA 497
Query: 241 SVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFP 300
S CS CL+ + V CC+ C+PC + + D + C CG W CF
Sbjct: 498 SRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEY--RLDEFTCADCGLGYWPNASLTGCFE 555
Query: 301 RTVVFLALREHTSWVLLAANTLLL--LLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSL 358
++ R +W + L L L G+F H TPVV+++G LC+++LG +
Sbjct: 556 LPQEYI--RWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGV 613
Query: 359 AAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIF---KFSTKVPTF 415
+ F +P+ C LR+ F++ S L ++ ++ IF + + P F
Sbjct: 614 FLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRF 673
Query: 416 YHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPARE-YQRFPHLVMLECTETNSLGF 474
+ A +IS QLLI + WLVV P +E +V L C ++
Sbjct: 674 ISP--ASQVAICLALIS--GQLLIVVAWLVVEAPGTGKETAPERREVVTLRCNHRDA-SM 728
Query: 475 ILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGKYL 534
+ + YN LL ++ + PEN+NEAK + F++ + W+AF V Y
Sbjct: 729 LGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYR 788
Query: 535 PAANMMAGLSSLSSG--FGGYFLPKCYVILCRPDLNSTEH 572
M SLS G F PK ++IL +P N H
Sbjct: 789 VQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSH 828
Score = 45.4 bits (106), Expect = 1e-04
Identities = 45/148 (30%), Positives = 63/148 (42%), Gaps = 24/148 (16%)
Query: 33 TLPGDYLLAGLFPLHSGCLQVRHRPEVTLCDRSCS-FNEH-GYHLFQAMRLGVEEINNST 90
TL GD +L GLFP+H + P C NEH G +AM ++ IN
Sbjct: 27 TLEGDLVLGGLFPVHQ-----KGGPA-----EDCGPVNEHRGIQRLEAMLFALDRINRDP 76
Query: 91 ALLPNITLGYQLYDVCSDSAN--------VYATLRVLSLPGQHHIELQGDLLHY--SPT- 139
LLP + LG + D CS + V A+L G HI G + +PT
Sbjct: 77 HLLPGVRLGAHILDSCSKDTHALEQALDFVRASLS-RGADGSRHICPDGSYATHGDAPTA 135
Query: 140 VLAVIGPDSTNRAATTAALLSPFLVPML 167
+ VIG ++ + A LL F +P +
Sbjct: 136 ITGVIGGSYSDVSIQVANLLRLFQIPQI 163
>gi|32528268 glutamate receptor, metabotropic 7 isoform b precursor
[Homo sapiens]
Length = 922
Score = 116 bits (291), Expect = 5e-26
Identities = 104/417 (24%), Positives = 180/417 (43%), Gaps = 24/417 (5%)
Query: 167 LLEQIHKVHFLLHKDT-VAFNDNRDPLSSYNIIAWDW-NGPKWTFTVLGSSTWSPVQLNI 224
LL+ I V+F T V FN N D Y+I + N + ++G T +QLNI
Sbjct: 448 LLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTSNPGYRLIGQWT-DELQLNI 506
Query: 225 NETKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQP 284
+ +QW ++P SVC+ C G ++ CC+ C PC + + D CQ
Sbjct: 507 ED--MQWGKGVREIPASVCTLPCKPGQRKKTQKGTPCCWTCEPCDG--YQYQFDEMTCQH 562
Query: 285 CGKEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLL--LLLLGTAGLFAWHLDTPV 342
C ++ E C + + + L H+ W ++ +L + + F + DTP+
Sbjct: 563 CPYDQRPNENRTGC--QDIPIIKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPI 620
Query: 343 VRSAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQL 402
VR++G L +++L + + +P C R+ LG I + L ++ ++
Sbjct: 621 VRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCISYAALLTKTNRI 680
Query: 403 IIIFKFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHL- 461
IF+ K T + + S QLL W V P +Y +
Sbjct: 681 YRIFEQGKKSVTAPRLISPTSQLAITSSLIS-VQLLGVFIWFGVDPPNIIIDYDEHKTMN 739
Query: 462 -----VMLECTETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNF 516
+L+C T+ L I + Y+ LL ++ + + +PEN+NEAK + F++
Sbjct: 740 PEQARGVLKCDITD-LQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTC 798
Query: 517 VSWIA----FFTTASVYDGKYLPAANMMAGLS-SLSSGFGGYFLPKCYVILCRPDLN 568
+ W+A FF TA + Y+ + ++ S S G ++PK Y+I+ P+LN
Sbjct: 799 IVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPELN 855
Score = 48.9 bits (115), Expect = 1e-05
Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 10/96 (10%)
Query: 14 LISCCWAFACHSTE--SSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVTLCDRSCSFNEH 71
++ C A A E + + GD L GLFP+H+ P C E+
Sbjct: 23 VLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHA------KGPSGVPCGDIK--REN 74
Query: 72 GYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCS 107
G H +AM +++IN+ LLPN+TLG ++ D CS
Sbjct: 75 GIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCS 110
>gi|4504147 glutamate receptor, metabotropic 7 isoform a precursor
[Homo sapiens]
Length = 915
Score = 116 bits (291), Expect = 5e-26
Identities = 104/417 (24%), Positives = 180/417 (43%), Gaps = 24/417 (5%)
Query: 167 LLEQIHKVHFLLHKDT-VAFNDNRDPLSSYNIIAWDW-NGPKWTFTVLGSSTWSPVQLNI 224
LL+ I V+F T V FN N D Y+I + N + ++G T +QLNI
Sbjct: 448 LLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTSNPGYRLIGQWT-DELQLNI 506
Query: 225 NETKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQP 284
+ +QW ++P SVC+ C G ++ CC+ C PC + + D CQ
Sbjct: 507 ED--MQWGKGVREIPASVCTLPCKPGQRKKTQKGTPCCWTCEPCDG--YQYQFDEMTCQH 562
Query: 285 CGKEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLL--LLLLGTAGLFAWHLDTPV 342
C ++ E C + + + L H+ W ++ +L + + F + DTP+
Sbjct: 563 CPYDQRPNENRTGC--QDIPIIKLEWHSPWAVIPVFLAMLGIIATIFVMATFIRYNDTPI 620
Query: 343 VRSAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQL 402
VR++G L +++L + + +P C R+ LG I + L ++ ++
Sbjct: 621 VRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRVFLGLGMCISYAALLTKTNRI 680
Query: 403 IIIFKFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHL- 461
IF+ K T + + S QLL W V P +Y +
Sbjct: 681 YRIFEQGKKSVTAPRLISPTSQLAITSSLIS-VQLLGVFIWFGVDPPNIIIDYDEHKTMN 739
Query: 462 -----VMLECTETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNF 516
+L+C T+ L I + Y+ LL ++ + + +PEN+NEAK + F++
Sbjct: 740 PEQARGVLKCDITD-LQIICSLGYSILLMVTCTVYAIKTRGVPENFNEAKPIGFTMYTTC 798
Query: 517 VSWIA----FFTTASVYDGKYLPAANMMAGLS-SLSSGFGGYFLPKCYVILCRPDLN 568
+ W+A FF TA + Y+ + ++ S S G ++PK Y+I+ P+LN
Sbjct: 799 IVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGMLYMPKVYIIIFHPELN 855
Score = 48.9 bits (115), Expect = 1e-05
Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 10/96 (10%)
Query: 14 LISCCWAFACHSTE--SSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVTLCDRSCSFNEH 71
++ C A A E + + GD L GLFP+H+ P C E+
Sbjct: 23 VLLCALAAAARGQEMYAPHSIRIEGDVTLGGLFPVHA------KGPSGVPCGDIK--REN 74
Query: 72 GYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCS 107
G H +AM +++IN+ LLPN+TLG ++ D CS
Sbjct: 75 GIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCS 110
>gi|187960069 glutamate receptor, metabotropic 8 isoform b precursor
[Homo sapiens]
Length = 908
Score = 114 bits (285), Expect = 2e-25
Identities = 103/420 (24%), Positives = 179/420 (42%), Gaps = 31/420 (7%)
Query: 167 LLEQIHKVHFLLHKDT-VAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNIN 225
LL I V+F T V FN+N D Y+I + + V+G T QL++
Sbjct: 442 LLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWT---NQLHLK 498
Query: 226 ETKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPC 285
+QW +++ P SVCS C G ++ CC+ C C + + D C+ C
Sbjct: 499 VEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNY--QVDELSCELC 556
Query: 286 GKEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAGL--FAWHLDTPVV 343
++ C + + + L H+ W ++ +L ++ T + F + DTP+V
Sbjct: 557 PLDQRPNMNRTGC--QLIPIIKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIV 614
Query: 344 RSAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLI 403
R++G L +++L + + P C R+ LG + L ++ ++
Sbjct: 615 RASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMCFSYAALLTKTNRIH 674
Query: 404 IIF---KFSTKVPTFYHAWVQNHGAGLFVMIS-SAAQLLICLTWLVVWTPLPAREYQRFP 459
IF K S P F + + L + S + QLL W VV P +Y
Sbjct: 675 RIFEQGKKSVTAPKFI-----SPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQR 729
Query: 460 HL------VMLECTETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLL 513
L +L+C + + L I + Y+ LL ++ + + +PE +NEAK + F++
Sbjct: 730 TLDPEKARGVLKC-DISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMY 788
Query: 514 FNFVSWIA----FFTTASVYDGKYLPAANMMAGLS-SLSSGFGGYFLPKCYVILCRPDLN 568
+ W+A FF TA + Y+ + +S S S G ++PK Y+I+ P+ N
Sbjct: 789 TTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQN 848
Score = 49.7 bits (117), Expect = 8e-06
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 8/84 (9%)
Query: 24 HSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVTLCDRSCSFNEHGYHLFQAMRLGV 83
HS E + + GD +L GLFP+H+ + E+ E G H +AM +
Sbjct: 32 HSQEYAHSIRVDGDIILGGLFPVHAKGERGVPCGELK--------KEKGIHRLEAMLYAI 83
Query: 84 EEINNSTALLPNITLGYQLYDVCS 107
++IN LL NITLG ++ D CS
Sbjct: 84 DQINKDPDLLSNITLGVRILDTCS 107
>gi|187960067 glutamate receptor, metabotropic 8 isoform a precursor
[Homo sapiens]
Length = 908
Score = 114 bits (285), Expect = 2e-25
Identities = 103/420 (24%), Positives = 179/420 (42%), Gaps = 31/420 (7%)
Query: 167 LLEQIHKVHFLLHKDT-VAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNIN 225
LL I V+F T V FN+N D Y+I + + V+G T QL++
Sbjct: 442 LLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWT---NQLHLK 498
Query: 226 ETKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPC 285
+QW +++ P SVCS C G ++ CC+ C C + + D C+ C
Sbjct: 499 VEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNY--QVDELSCELC 556
Query: 286 GKEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAGL--FAWHLDTPVV 343
++ C + + + L H+ W ++ +L ++ T + F + DTP+V
Sbjct: 557 PLDQRPNMNRTGC--QLIPIIKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIV 614
Query: 344 RSAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLI 403
R++G L +++L + + P C R+ LG + L ++ ++
Sbjct: 615 RASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMCFSYAALLTKTNRIH 674
Query: 404 IIF---KFSTKVPTFYHAWVQNHGAGLFVMIS-SAAQLLICLTWLVVWTPLPAREYQRFP 459
IF K S P F + + L + S + QLL W VV P +Y
Sbjct: 675 RIFEQGKKSVTAPKFI-----SPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQR 729
Query: 460 HL------VMLECTETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLL 513
L +L+C + + L I + Y+ LL ++ + + +PE +NEAK + F++
Sbjct: 730 TLDPEKARGVLKC-DISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMY 788
Query: 514 FNFVSWIA----FFTTASVYDGKYLPAANMMAGLS-SLSSGFGGYFLPKCYVILCRPDLN 568
+ W+A FF TA + Y+ + +S S S G ++PK Y+I+ P+ N
Sbjct: 789 TTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQN 848
Score = 49.7 bits (117), Expect = 8e-06
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 8/84 (9%)
Query: 24 HSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVTLCDRSCSFNEHGYHLFQAMRLGV 83
HS E + + GD +L GLFP+H+ + E+ E G H +AM +
Sbjct: 32 HSQEYAHSIRVDGDIILGGLFPVHAKGERGVPCGELK--------KEKGIHRLEAMLYAI 83
Query: 84 EEINNSTALLPNITLGYQLYDVCS 107
++IN LL NITLG ++ D CS
Sbjct: 84 DQINKDPDLLSNITLGVRILDTCS 107
>gi|194248052 glutamate receptor, metabotropic 2 isoform b [Homo
sapiens]
Length = 254
Score = 68.6 bits (166), Expect = 2e-11
Identities = 59/211 (27%), Positives = 90/211 (42%), Gaps = 11/211 (5%)
Query: 368 FFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIF---KFSTKVPTFYHAWVQNHG 424
F +P+ C LR+ F++ S L ++ ++ IF + + P F Q
Sbjct: 5 FIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQV-- 62
Query: 425 AGLFVMISSAAQLLICLTWLVVWTPLPAREYQ-RFPHLVMLECTETNSLGFILAFLYNGL 483
A +IS QLLI + WLVV P +E +V L C ++ + + YN L
Sbjct: 63 AICLALISG--QLLIVVAWLVVEAPGTGKETAPERREVVTLRCNHRDA-SMLGSLAYNVL 119
Query: 484 LSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGKYLPAANMMAGL 543
L ++ + PEN+NEAK + F++ + W+AF V Y M
Sbjct: 120 LIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVS 179
Query: 544 SSLSSG--FGGYFLPKCYVILCRPDLNSTEH 572
SLS G F PK ++IL +P N H
Sbjct: 180 VSLSGSVVLGCLFAPKLHIILFQPQKNVVSH 210
>gi|33356136 hypothetical protein LOC222223 isoform 2 [Homo sapiens]
Length = 789
Score = 39.3 bits (90), Expect = 0.010
Identities = 14/35 (40%), Positives = 21/35 (60%)
Query: 264 ECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTC 298
EC PC GTF NK + CQ C + ++ +G++ C
Sbjct: 49 ECFPCKPGTFSNKPGSFNCQVCPRNTYSEKGAKEC 83
>gi|218505750 hypothetical protein LOC222223 isoform 1 [Homo
sapiens]
Length = 1029
Score = 39.3 bits (90), Expect = 0.010
Identities = 14/35 (40%), Positives = 21/35 (60%)
Query: 264 ECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTC 298
EC PC GTF NK + CQ C + ++ +G++ C
Sbjct: 289 ECFPCKPGTFSNKPGSFNCQVCPRNTYSEKGAKEC 323
>gi|239749596 PREDICTED: hypothetical protein XP_002347099 [Homo
sapiens]
Length = 853
Score = 38.9 bits (89), Expect = 0.013
Identities = 32/114 (28%), Positives = 42/114 (36%), Gaps = 25/114 (21%)
Query: 242 VCSSDCLEGHQRVVTG-------FHHCCFE--------CVPCGAGTFLNKSDLYRCQPCG 286
+C+SDCL G RV G H C E C C A L+ D + C C
Sbjct: 641 ICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPANLVLHMDDSH-CLHCC 699
Query: 287 KEEWAPEGSQ---------TCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTA 331
P + C RT EH L ++++L+LLLG A
Sbjct: 700 NTSDPPSAQECCDCQDTTDECILRTSKVRPATEHFKTALFITSSMMLVLLLGAA 753
>gi|239743863 PREDICTED: hypothetical protein XP_002342982 [Homo
sapiens]
Length = 853
Score = 38.9 bits (89), Expect = 0.013
Identities = 32/114 (28%), Positives = 42/114 (36%), Gaps = 25/114 (21%)
Query: 242 VCSSDCLEGHQRVVTG-------FHHCCFE--------CVPCGAGTFLNKSDLYRCQPCG 286
+C+SDCL G RV G H C E C C A L+ D + C C
Sbjct: 641 ICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPANLVLHMDDSH-CLHCC 699
Query: 287 KEEWAPEGSQ---------TCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTA 331
P + C RT EH L ++++L+LLLG A
Sbjct: 700 NTSDPPSAQECCDCQDTTDECILRTSKVRPATEHFKTALFITSSMMLVLLLGAA 753
>gi|239755070 PREDICTED: similar to proprotein convertase
subtilisin/kexin type 5 [Homo sapiens]
Length = 853
Score = 37.7 bits (86), Expect = 0.030
Identities = 31/113 (27%), Positives = 40/113 (35%), Gaps = 23/113 (20%)
Query: 242 VCSSDCLEGHQRVVTG-------FHHCCFECVPCGA-------GTFLNKSDLYRCQPCGK 287
+C+SDCL G RV G H C EC GA + D C C
Sbjct: 641 ICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPANLVLHMDESHCLHCCN 700
Query: 288 EEWAPEGSQ---------TCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTA 331
P + C RT EH L ++++L+LLLG A
Sbjct: 701 TSDPPSAQECCDCQDTTDECILRTSKVRPATEHFKTALFITSSMMLVLLLGAA 753
>gi|83716019 zinc finger protein 284 [Homo sapiens]
Length = 593
Score = 37.4 bits (85), Expect = 0.039
Identities = 24/72 (33%), Positives = 31/72 (43%), Gaps = 18/72 (25%)
Query: 232 HGKDNQVPKSVCS-----SDCLEGHQRVVTGFHHCCFECVPCGAGTFLN----------- 275
H D +VC S CL HQRV G F+C CG ++N
Sbjct: 365 HTGDKPYNCNVCGKGFRWSSCLSRHQRVHNG--ETTFKCDGCGKRFYMNSQGHSHQRAYR 422
Query: 276 KSDLYRCQPCGK 287
+ +LY+CQ CGK
Sbjct: 423 EEELYKCQKCGK 434
>gi|7662424 zinc finger protein 510 [Homo sapiens]
Length = 683
Score = 35.4 bits (80), Expect = 0.15
Identities = 26/66 (39%), Positives = 28/66 (42%), Gaps = 15/66 (22%)
Query: 234 KDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDL------------YR 281
K N+ KS C L HQR TG FEC CG TF KS L Y+
Sbjct: 405 KCNECGKSFCQKGHLIQHQRTHTG--EKPFECSECGK-TFSQKSHLSTHQRIHTAEKPYK 461
Query: 282 CQPCGK 287
C CGK
Sbjct: 462 CNECGK 467
Score = 35.0 bits (79), Expect = 0.19
Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 15/66 (22%)
Query: 234 KDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDL------------YR 281
K N+ K+ L GHQR+ TG +EC CG TF+ KS L ++
Sbjct: 461 KCNECGKTFVQKSTLRGHQRIHTG--EKPYECSECGK-TFVQKSTLRDHHRIHTGEKSFQ 517
Query: 282 CQPCGK 287
C CGK
Sbjct: 518 CNQCGK 523
>gi|37655173 zinc finger protein 155 [Homo sapiens]
Length = 538
Score = 34.3 bits (77), Expect = 0.33
Identities = 21/59 (35%), Positives = 26/59 (44%), Gaps = 13/59 (22%)
Query: 240 KSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNK-----------SDLYRCQPCGK 287
KS S CL HQRV +G F+C CG G + N Y+C+ CGK
Sbjct: 379 KSFRWSSCLLNHQRVHSG--EKSFKCEECGKGFYTNSQLSSHQRSHSGEKPYKCEECGK 435
>gi|37655171 zinc finger protein 155 [Homo sapiens]
Length = 538
Score = 34.3 bits (77), Expect = 0.33
Identities = 21/59 (35%), Positives = 26/59 (44%), Gaps = 13/59 (22%)
Query: 240 KSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNK-----------SDLYRCQPCGK 287
KS S CL HQRV +G F+C CG G + N Y+C+ CGK
Sbjct: 379 KSFRWSSCLLNHQRVHSG--EKSFKCEECGKGFYTNSQLSSHQRSHSGEKPYKCEECGK 435
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.139 0.456
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,568,374
Number of Sequences: 37866
Number of extensions: 1086355
Number of successful extensions: 3473
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 3308
Number of HSP's gapped (non-prelim): 138
length of query: 587
length of database: 18,247,518
effective HSP length: 108
effective length of query: 479
effective length of database: 14,157,990
effective search space: 6781677210
effective search space used: 6781677210
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.