Search of human proteins with 29029559

Search of human proteins with 29029559

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|29029559 CSE1 chromosome segregation 1-like protein [Homo
sapiens]
         (971 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|29029559 CSE1 chromosome segregation 1-like protein [Homo sap...  1924   0.0  
gi|5453998 importin 7 [Homo sapiens]                                   97   6e-20
gi|53759103 importin 8 [Homo sapiens]                                  92   2e-18
gi|198041777 Ran binding protein 11 isoform 1 [Homo sapiens]           67   8e-11
gi|39725950 Ran binding protein 11 isoform 2 [Homo sapiens]            67   8e-11
gi|21361659 importin 9 [Homo sapiens]                                  60   1e-08
gi|23510381 transportin 1 isoform 2 [Homo sapiens]                     53   2e-06
gi|133925811 transportin 1 isoform 1 [Homo sapiens]                    53   2e-06
gi|209969838 transportin 2 (importin 3, karyopherin beta 2b) iso...    43   0.001
gi|209969836 transportin 2 (importin 3, karyopherin beta 2b) iso...    43   0.001
gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isof...    43   0.001
gi|22748937 exportin 5 [Homo sapiens]                                  40   0.014
gi|4507943 exportin 1 [Homo sapiens]                                   37   0.090
gi|46049063 exportin 6 [Homo sapiens]                                  35   0.26 
gi|21955154 NLR family, pyrin domain containing 12 isoform 2 [Ho...    35   0.34 
gi|189027129 phosphodiesterase 12 [Homo sapiens]                       32   3.8  
gi|62460637 importin 4 [Homo sapiens]                                  31   4.9  
gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo ...    31   6.4  
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s...    30   8.4  

>gi|29029559 CSE1 chromosome segregation 1-like protein [Homo
           sapiens]
          Length = 971

 Score = 1924 bits (4985), Expect = 0.0
 Identities = 971/971 (100%), Positives = 971/971 (100%)

Query: 1   MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLEKSQDNVIKV 60
           MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLEKSQDNVIKV
Sbjct: 1   MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLEKSQDNVIKV 60

Query: 61  CASVTFKNYIKRNWRIVEDEPNKICEADRVAIKANIVHLMLSSPEQIQKQLSDAISIIGR 120
           CASVTFKNYIKRNWRIVEDEPNKICEADRVAIKANIVHLMLSSPEQIQKQLSDAISIIGR
Sbjct: 61  CASVTFKNYIKRNWRIVEDEPNKICEADRVAIKANIVHLMLSSPEQIQKQLSDAISIIGR 120

Query: 121 EDFPQKWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAF 180
           EDFPQKWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAF
Sbjct: 121 EDFPQKWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAF 180

Query: 181 ALPLTNLFKATIELCSTHANDASALRILFSSLILISKLFYSLNFQDLPEFFEDNMETWMN 240
           ALPLTNLFKATIELCSTHANDASALRILFSSLILISKLFYSLNFQDLPEFFEDNMETWMN
Sbjct: 181 ALPLTNLFKATIELCSTHANDASALRILFSSLILISKLFYSLNFQDLPEFFEDNMETWMN 240

Query: 241 NFHTLLTLDNKLLQTDDEEEAGLLELLKSQICDNAALYAQKYDEEFQRYLPRFVTAIWNL 300
           NFHTLLTLDNKLLQTDDEEEAGLLELLKSQICDNAALYAQKYDEEFQRYLPRFVTAIWNL
Sbjct: 241 NFHTLLTLDNKLLQTDDEEEAGLLELLKSQICDNAALYAQKYDEEFQRYLPRFVTAIWNL 300

Query: 301 LVTTGQEVKYDLLVSNAIQFLASVCERPHYKNLFEDQNTLTSICEKVIVPNMEFRAADEE 360
           LVTTGQEVKYDLLVSNAIQFLASVCERPHYKNLFEDQNTLTSICEKVIVPNMEFRAADEE
Sbjct: 301 LVTTGQEVKYDLLVSNAIQFLASVCERPHYKNLFEDQNTLTSICEKVIVPNMEFRAADEE 360

Query: 361 AFEDNSEEYIRRDLEGSDIDTRRRAACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNP 420
           AFEDNSEEYIRRDLEGSDIDTRRRAACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNP
Sbjct: 361 AFEDNSEEYIRRDLEGSDIDTRRRAACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNP 420

Query: 421 SVNWKHKDAAIYLVTSLASKAQTQKHGITQANELVNLTEFFVNHILPDLKSANVNEFPVL 480
           SVNWKHKDAAIYLVTSLASKAQTQKHGITQANELVNLTEFFVNHILPDLKSANVNEFPVL
Sbjct: 421 SVNWKHKDAAIYLVTSLASKAQTQKHGITQANELVNLTEFFVNHILPDLKSANVNEFPVL 480

Query: 481 KADGIKYIMIFRNQVPKEHLLVSIPLLINHLQAESIVVHTYAAHALERLFTMRGPNNATL 540
           KADGIKYIMIFRNQVPKEHLLVSIPLLINHLQAESIVVHTYAAHALERLFTMRGPNNATL
Sbjct: 481 KADGIKYIMIFRNQVPKEHLLVSIPLLINHLQAESIVVHTYAAHALERLFTMRGPNNATL 540

Query: 541 FTAAEIAPFVEILLTNLFKALTLPGSSENEYIMKAIMRSFSLLQEAIIPYIPTLITQLTQ 600
           FTAAEIAPFVEILLTNLFKALTLPGSSENEYIMKAIMRSFSLLQEAIIPYIPTLITQLTQ
Sbjct: 541 FTAAEIAPFVEILLTNLFKALTLPGSSENEYIMKAIMRSFSLLQEAIIPYIPTLITQLTQ 600

Query: 601 KLLAVSKNPSKPHFNHYMFEAICLSIRITCKANPAAVVNFEEALFLVFTEILQNDVQEFI 660
           KLLAVSKNPSKPHFNHYMFEAICLSIRITCKANPAAVVNFEEALFLVFTEILQNDVQEFI
Sbjct: 601 KLLAVSKNPSKPHFNHYMFEAICLSIRITCKANPAAVVNFEEALFLVFTEILQNDVQEFI 660

Query: 661 PYVFQVMSLLLETHKNDIPSSYMALFPHLLQPVLWERTGNIPALVRLLQAFLERGSNTIA 720
           PYVFQVMSLLLETHKNDIPSSYMALFPHLLQPVLWERTGNIPALVRLLQAFLERGSNTIA
Sbjct: 661 PYVFQVMSLLLETHKNDIPSSYMALFPHLLQPVLWERTGNIPALVRLLQAFLERGSNTIA 720

Query: 721 SAAADKIPGLLGVFQKLIASKANDHQGFYLLNSIIEHMPPESVDQYRKQIFILLFQRLQN 780
           SAAADKIPGLLGVFQKLIASKANDHQGFYLLNSIIEHMPPESVDQYRKQIFILLFQRLQN
Sbjct: 721 SAAADKIPGLLGVFQKLIASKANDHQGFYLLNSIIEHMPPESVDQYRKQIFILLFQRLQN 780

Query: 781 SKTTKFIKSFLVFINLYCIKYGALALQEIFDGIQPKMFGMVLEKIIIPEIQKVSGNVEKK 840
           SKTTKFIKSFLVFINLYCIKYGALALQEIFDGIQPKMFGMVLEKIIIPEIQKVSGNVEKK
Sbjct: 781 SKTTKFIKSFLVFINLYCIKYGALALQEIFDGIQPKMFGMVLEKIIIPEIQKVSGNVEKK 840

Query: 841 ICAVGITKLLTECPPMMDTEYTKLWTPLLQSLIGLFELPEDDTIPDEEHFIDIEDTPGYQ 900
           ICAVGITKLLTECPPMMDTEYTKLWTPLLQSLIGLFELPEDDTIPDEEHFIDIEDTPGYQ
Sbjct: 841 ICAVGITKLLTECPPMMDTEYTKLWTPLLQSLIGLFELPEDDTIPDEEHFIDIEDTPGYQ 900

Query: 901 TAFSQLAFAGKKEHDPVGQMVNNPKIHLAQSLHKLSTACPGRVPSMVSTSLNAEALQYLQ 960
           TAFSQLAFAGKKEHDPVGQMVNNPKIHLAQSLHKLSTACPGRVPSMVSTSLNAEALQYLQ
Sbjct: 901 TAFSQLAFAGKKEHDPVGQMVNNPKIHLAQSLHKLSTACPGRVPSMVSTSLNAEALQYLQ 960

Query: 961 GYLQAASVTLL 971
           GYLQAASVTLL
Sbjct: 961 GYLQAASVTLL 971


>gi|5453998 importin 7 [Homo sapiens]
          Length = 1038

 Score = 97.4 bits (241), Expect = 6e-20
 Identities = 124/486 (25%), Positives = 209/486 (43%), Gaps = 55/486 (11%)

Query: 10  TLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLEKSQ-DNVIKVCASVTFKN 68
           T+ E L+ T+DP  A+R  AE+ L     + N+   LL +    Q D  ++    +  KN
Sbjct: 5   TIIEALRGTMDP--ALREAAERQLNEAHKSLNFVSTLLQITMSEQLDLPVRQAGVIYLKN 62

Query: 69  YIKRNWRIVEDEPNKIC-----EADRVAIKANIVHLMLSSPEQIQKQLSDAISIIGREDF 123
            I + W   E  P  I      E DR  I+ NIV  ++ SPE I+ QL+  I  I + D+
Sbjct: 63  MITQYWPDRETAPGDISPYTIPEEDRHCIRENIVEAIIHSPELIRVQLTTCIHHIIKHDY 122

Query: 124 PQKWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALP 183
           P +W  ++ ++    QS +     G+L   + L K Y  E+K  E  + +   +  F   
Sbjct: 123 PSRWTAIVDKIGFYLQSDNSACWLGILLCLYQLVKNY--EYKKPEERSPLVAAMQHFLPV 180

Query: 184 LTNLFKATIELCSTHANDASALRILFSSLILISKLFYSLNFQDLP--EFFEDNMETWMNN 241
           L + F   I+L S    D S   +L    I   K+FY+L    LP     + N+  W+  
Sbjct: 181 LKDRF---IQLLS----DQSDQSVLIQKQIF--KIFYALVQYTLPLELINQQNLTEWIEI 231

Query: 242 FHTLLTLD--NKLLQT--DDEEEAGLLELLKSQICDNAALY---------AQKYDEEFQR 288
             T++  D  N+ LQ   DD  E    +  K  +   A L+         +++Y+E  + 
Sbjct: 232 LKTVVNRDVPNETLQVEEDDRPELPWWKCKKWALHILARLFERYGSPGNVSKEYNEFAEV 291

Query: 289 YLPRFVTAIWNLLVTTGQEVK-----YDLLVSNAIQFL-ASVCERPHYKNLFEDQNTLTS 342
           +L  F   +  +L+    + K        ++   + ++   V     +KNL   +  +  
Sbjct: 292 FLKAFAVGVQQVLLKVLYQYKEKQYMAPRVLQQTLNYINQGVSHALTWKNL---KPHIQG 348

Query: 343 ICEKVIVPNMEFRAADEEAFEDNSEEYIRRDLE-GSDIDTRRRAACDLVRGLCKFFEGPV 401
           I + VI P M +  ADEE ++++  EYIR   +   D  +   AA  L+   C      V
Sbjct: 349 IIQDVIFPLMCYTDADEELWQEDPYEYIRMKFDVFEDFISPTTAAQTLLFTACS-KRKEV 407

Query: 402 TGIFSGYVNSMLQEYAKNPSVNWKHKDAAIYLVTSLASKAQTQKHGITQANELVNLTEFF 461
                G+   +L E    P+ + + KD A++++ SLA     +K    Q   ++      
Sbjct: 408 LQKTMGFCYQILTE----PNADPRKKDGALHMIGSLAEILLKKKIYKDQMEYMLQ----- 458

Query: 462 VNHILP 467
            NH+ P
Sbjct: 459 -NHVFP 463


>gi|53759103 importin 8 [Homo sapiens]
          Length = 1037

 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 198/939 (21%), Positives = 384/939 (40%), Gaps = 138/939 (14%)

Query: 7   NLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNY------PLLLLTLLEKSQDNVIKV 60
           +L  + + LK T+DP   +R  AE  L     NQ+Y      P LL  ++    +  ++ 
Sbjct: 2   DLNRIIQALKGTIDPK--LRIAAENEL-----NQSYKIINFAPSLLRIIVSDHVEFPVRQ 54

Query: 61  CASVTFKNYIKRNWRIVEDEPNK------ICEADRVAIKANIVHLMLSSPEQIQKQLSDA 114
            A++  KN + + W   E  P +      I E DR  I+ NIV  ++ SP+ ++ QL+  
Sbjct: 55  AAAIYLKNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMC 114

Query: 115 ISIIGREDFPQKWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIK 174
           +  I + DFP  WP ++ ++    QS       G L   + L K Y  E+K  E   E +
Sbjct: 115 LRAIIKHDFPGHWPGVVDKIDYYLQSQSSASWLGSLLCLYQLVKTY--EYKKAE---ERE 169

Query: 175 LVLDAFALPLTNLFKATIELCSTHANDASALRILFSSLILISKLFYSLNFQDLPEFFEDN 234
            ++ A  + L  + +  ++L      D+S   +L    IL  K+FY+L    LP    +N
Sbjct: 170 PLIIAMQIFLPRIQQQIVQLLP----DSSYYSVLLQKQIL--KIFYALVQYALPLQLVNN 223

Query: 235 --METWMNNFHTLL--TLDNKLLQTDDEEEAGLL--ELLKSQICDNAALY---------A 279
             M TWM  F T++  T+  + L  D+++   L+  +  K  +   A L+          
Sbjct: 224 QTMTTWMEIFRTIIDRTVPPETLHIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVT 283

Query: 280 QKYDEEFQRYLPRFVTAIWNLLVTTGQEVK-------------YDLLVSNAIQFLASVCE 326
           ++Y E  + +L  +   I  +L+    + +             ++ L    +  +     
Sbjct: 284 KEYFEFSEFFLKTYAVGIQQVLLKILDQYRQKEYVAPRVLQQAFNYLNQGVVHSITWKQM 343

Query: 327 RPHYKNLFEDQNTLTSICEKVIVPNMEFRAADEEAFEDNSEEYIRRDLE-GSDIDTRRRA 385
           +PH +N+ ED          VI   M ++  DEE ++++  EYIR   +   D  +   A
Sbjct: 344 KPHIQNISED----------VIFSVMCYKDEDEELWQEDPYEYIRMKFDIFEDYASPTTA 393

Query: 386 ACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNPSVNWKHKDAAIYLVTSLASKAQTQK 445
           A  L+    K  +  +  +      +   +   +P+ + + KD A++++ SLA +   +K
Sbjct: 394 AQTLLYTAAKKRKEVLPKMM-----AFCYQILTDPNFDPRKKDGALHVIGSLA-EILLKK 447

Query: 446 HGITQANELVNLTEFFVNHILPDLKSANVNEFPVLKADGIKYI-----MIFRNQVPKEHL 500
                  EL     F  NH+ P L    ++    L+A     +     + F N++   +L
Sbjct: 448 SLFKDQMEL-----FLQNHVFPLL----LSNLGYLRARSCWVLHAFSSLKFHNEL---NL 495

Query: 501 LVSIPLLINHL-QAESIVVHTYAAHALERLFTMRGPNNATLFTAAEIAPFVEILLTNLFK 559
             ++ L    L + + + V   AA AL+ L +      A  +    + P ++ L      
Sbjct: 496 RNAVELAKKSLIEDKEMPVKVEAALALQSLIS--NQIQAKEYMKPHVRPIMQEL------ 547

Query: 560 ALTLPGSSENEYIMKAIMRSFSLLQEAIIPYIPTLITQLTQKLLAV-SKNPSKPHFNHYM 618
            L +   +EN+ +   I +      +     + ++   +TQ L  +  K      +    
Sbjct: 548 -LHIVRETENDDVTNVIQKMICEYSQE----VASIAVDMTQHLAEIFGKVLQSDEYEEVE 602

Query: 619 FEAI-CLSIRITCKANPAAVVNFEEALFLVFTEILQNDVQEFIPYVFQVMSLLLETHKND 677
            + +  + I  T       V + +E      T+ L+N     I  V Q    ++E ++  
Sbjct: 603 DKTVMAMGILHTIDTILTVVEDHKE-----ITQQLENICLRIIDLVLQ--KHVIEFYEEI 655

Query: 678 IPSSYMALFPHLLQPVLWERTGNI------------PALVRLLQAFLERGSNTIASAAAD 725
           +  +Y +L  H + P +W+  G +              ++ LL  ++   ++T+ S  A 
Sbjct: 656 LSLAY-SLTCHSISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTIDTDTLLS-NAK 713

Query: 726 KIPGLLGVFQKLIASKANDHQGFY---LLNSIIEHMPPESVDQYRKQIFILLFQRLQNSK 782
            +  L  + +K++   A +    +   LL  II       +DQ       L+ +RL    
Sbjct: 714 HLEILFTMCRKVLCGDAGEDAECHAAKLLEVIILQCKGRGIDQCIPLFVQLVLERLTRGV 773

Query: 783 TTKFIKSFLVFINLYCIKYGALALQEIFDGIQ-PKMFGMVLEKII---IPEIQKVSGNVE 838
            T  +++  + + +  + Y    L    + IQ P   G +  + I   + +     G+ +
Sbjct: 774 KTSELRTMCLQVAIAALYYNPDLLLHTLERIQLPHNPGPITVQFINQWMNDTDCFLGHHD 833

Query: 839 KKICAVGITKL--LTECPPMMDTEYTKLWTPLLQSLIGL 875
           +K+C +G++ L  L   PP +D    ++   +L   +GL
Sbjct: 834 RKMCIIGLSILLELQNRPPAVDAVVGQIVPSILFLFLGL 872


>gi|198041777 Ran binding protein 11 isoform 1 [Homo sapiens]
          Length = 1015

 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 165/860 (19%), Positives = 309/860 (35%), Gaps = 117/860 (13%)

Query: 1   MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQN-YPLLLLTLLEKSQDNVIK 59
           M+L+ A+   L + L +    D A+ +PAE+ L+  E     Y +LL      + D  ++
Sbjct: 41  MDLNSASTVVL-QVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVR 99

Query: 60  VCASVTFKNYIKRNWRIVEDEPNKICEADRVAIKANIVHLMLSSPEQIQKQLSDAISIIG 119
             A + FK+ I R WR V   P+ + E ++  ++A ++        QI  Q++  I+ + 
Sbjct: 100 WLAVLYFKHGIDRYWRRVA--PHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVA 157

Query: 120 REDFPQKWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDA 179
           R D P++WP+L+  ++   +  D    +  L T + + K       S  L  + KL  D 
Sbjct: 158 RLDCPRQWPELIPTLIESVKVQDDLRQHRALLTFYHVTK----TLASKRLAADRKLFYDL 213

Query: 180 ------FALPLTNLFKATIELCSTHANDASALRILFSSLILISKL--------------- 218
                 FA  L N    T     +  N+A+ L  L  +L+ +  L               
Sbjct: 214 ASGIYNFACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPHKNM 273

Query: 219 ----FYSLNFQDLPEFFEDNMETWMNNF------HTLLTLDNKLLQTDDEEEAGLLELLK 268
               F    F+ L +F E +     +N        T++     LL   D+       L++
Sbjct: 274 EVMGFLHGIFERLKQFLECSRSIGTDNVCRDRLEKTIILFTKVLLDFLDQHPFSFTPLIQ 333

Query: 269 SQICDNAALYAQKYDEEFQRYLPRFVTAIWNLLVTTGQEVKYDLLVSNAIQFLASVCERP 328
             +  + +    +  E       RF+    NL+    +   Y     N         E  
Sbjct: 334 RSLEFSVSYVFTEVGEGVT--FERFIVQCMNLIKMIVKNYAYK-PSKNFEDSSPETLEAH 390

Query: 329 HYKNLFEDQNTLTSICEKVIVPNMEFRAADEEAFEDNSEEYIRRDLEGSDIDTRRRAACD 388
             K  F    TLT IC +++         +   +E++ E +   +  G       R   +
Sbjct: 391 KIKMAFFTYPTLTEICRRLVSHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCTE 450

Query: 389 -LVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNPSVNWKHKDAAIYLVTSLASKAQTQKHG 447
            L   +   +   +T +    + + LQ       +N      A+Y    LA+        
Sbjct: 451 VLFIDIFHEYNQTLTPVLLEMMQT-LQGPTNVEDMNALLIKDAVYNAVGLAA-------- 501

Query: 448 ITQANELVNLTEFFVNHILPDLKSANVNEFPVLKADGIKYIMIFRNQVPKEHLLVSIPLL 507
             +  + V+  ++F N +LP+L+                                     
Sbjct: 502 -YELFDSVDFDQWFKNQLLPELQ------------------------------------- 523

Query: 508 INHLQAESIVVHTYAAHALERLFTMRGPNNATLFTAAEIAPFVEILLTNLFKALTLPGSS 567
                    V+H        R+  + G   +  F + ++ P +   + NL +   L    
Sbjct: 524 ---------VIHNRYKPLRRRVIWLIGQWISVKFKS-DLRPMLYEAICNLLQDQDLVVRI 573

Query: 568 ENEYIMKAIMRSFSLLQEAIIPYIPTLITQLTQKLLAVSKNPSKPHFNHYMFEAICLSIR 627
           E    +K  +  F    +  +PY+ T+ T L Q L  V++  +K H  H +    C+  R
Sbjct: 574 ETATTLKLTVDDFEFRTDQFLPYLETMFTLLFQLLQQVTECDTKMHVLHVL---SCVIER 630

Query: 628 ITCKANPAAVVNFEEALFLVFTEILQNDVQEFIPYVFQVMSLLLETHKNDIPSSYMALFP 687
           +  +  P           + +  +L    +E       +++ L+   +  + +    L+P
Sbjct: 631 VNMQIRPYV------GCLVQYLPLLWKQSEEHNMLRCAILTTLIHLVQG-LGADSKNLYP 683

Query: 688 HLLQPVLWERTGNIPALVRLLQAFLERGSNTIASAAADKIPGLLGVFQK----LIASKAN 743
            LL  +      + P  V LL+  LE    T+ ++     P LL +FQ     L  S  N
Sbjct: 684 FLLPVIQLSTDVSQPPHVYLLEDGLELWLVTLENSPC-ITPELLRIFQNMSPLLELSSEN 742

Query: 744 DHQGFYLLNSIIEHMPPESVDQYRKQIFILLFQRLQNSKTTKFIKSFLVFINLYCIKYGA 803
               F ++N  I     E +  Y   +     + L+   T   ++   V  N   +K   
Sbjct: 743 LRTCFKIINGYIFLSSTEFLQTYAVGLCQSFCELLKEITTEGQVQVLKVVEN--ALKVNP 800

Query: 804 LALQEIFDGIQPKMFGMVLE 823
           +   ++F  I P +F  ++E
Sbjct: 801 ILGPQMFQPILPYVFKGIIE 820


>gi|39725950 Ran binding protein 11 isoform 2 [Homo sapiens]
          Length = 975

 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 165/860 (19%), Positives = 309/860 (35%), Gaps = 117/860 (13%)

Query: 1   MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQN-YPLLLLTLLEKSQDNVIK 59
           M+L+ A+   L + L +    D A+ +PAE+ L+  E     Y +LL      + D  ++
Sbjct: 1   MDLNSASTVVL-QVLTQATSQDTAVLKPAEEQLKQWETQPGFYSVLLNIFTNHTLDINVR 59

Query: 60  VCASVTFKNYIKRNWRIVEDEPNKICEADRVAIKANIVHLMLSSPEQIQKQLSDAISIIG 119
             A + FK+ I R WR V   P+ + E ++  ++A ++        QI  Q++  I+ + 
Sbjct: 60  WLAVLYFKHGIDRYWRRVA--PHALSEEEKTTLRAGLITNFNEPINQIATQIAVLIAKVA 117

Query: 120 REDFPQKWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDA 179
           R D P++WP+L+  ++   +  D    +  L T + + K       S  L  + KL  D 
Sbjct: 118 RLDCPRQWPELIPTLIESVKVQDDLRQHRALLTFYHVTK----TLASKRLAADRKLFYDL 173

Query: 180 ------FALPLTNLFKATIELCSTHANDASALRILFSSLILISKL--------------- 218
                 FA  L N    T     +  N+A+ L  L  +L+ +  L               
Sbjct: 174 ASGIYNFACSLWNHHTDTFLQEVSSGNEAAILSSLERTLLSLKVLRKLTVNGFVEPHKNM 233

Query: 219 ----FYSLNFQDLPEFFEDNMETWMNNF------HTLLTLDNKLLQTDDEEEAGLLELLK 268
               F    F+ L +F E +     +N        T++     LL   D+       L++
Sbjct: 234 EVMGFLHGIFERLKQFLECSRSIGTDNVCRDRLEKTIILFTKVLLDFLDQHPFSFTPLIQ 293

Query: 269 SQICDNAALYAQKYDEEFQRYLPRFVTAIWNLLVTTGQEVKYDLLVSNAIQFLASVCERP 328
             +  + +    +  E       RF+    NL+    +   Y     N         E  
Sbjct: 294 RSLEFSVSYVFTEVGEGVT--FERFIVQCMNLIKMIVKNYAYK-PSKNFEDSSPETLEAH 350

Query: 329 HYKNLFEDQNTLTSICEKVIVPNMEFRAADEEAFEDNSEEYIRRDLEGSDIDTRRRAACD 388
             K  F    TLT IC +++         +   +E++ E +   +  G       R   +
Sbjct: 351 KIKMAFFTYPTLTEICRRLVSHYFLLTEEELTMWEEDPEGFTVEETGGDSWKYSLRPCTE 410

Query: 389 -LVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNPSVNWKHKDAAIYLVTSLASKAQTQKHG 447
            L   +   +   +T +    + + LQ       +N      A+Y    LA+        
Sbjct: 411 VLFIDIFHEYNQTLTPVLLEMMQT-LQGPTNVEDMNALLIKDAVYNAVGLAA-------- 461

Query: 448 ITQANELVNLTEFFVNHILPDLKSANVNEFPVLKADGIKYIMIFRNQVPKEHLLVSIPLL 507
             +  + V+  ++F N +LP+L+                                     
Sbjct: 462 -YELFDSVDFDQWFKNQLLPELQ------------------------------------- 483

Query: 508 INHLQAESIVVHTYAAHALERLFTMRGPNNATLFTAAEIAPFVEILLTNLFKALTLPGSS 567
                    V+H        R+  + G   +  F + ++ P +   + NL +   L    
Sbjct: 484 ---------VIHNRYKPLRRRVIWLIGQWISVKFKS-DLRPMLYEAICNLLQDQDLVVRI 533

Query: 568 ENEYIMKAIMRSFSLLQEAIIPYIPTLITQLTQKLLAVSKNPSKPHFNHYMFEAICLSIR 627
           E    +K  +  F    +  +PY+ T+ T L Q L  V++  +K H  H +    C+  R
Sbjct: 534 ETATTLKLTVDDFEFRTDQFLPYLETMFTLLFQLLQQVTECDTKMHVLHVL---SCVIER 590

Query: 628 ITCKANPAAVVNFEEALFLVFTEILQNDVQEFIPYVFQVMSLLLETHKNDIPSSYMALFP 687
           +  +  P           + +  +L    +E       +++ L+   +  + +    L+P
Sbjct: 591 VNMQIRPYV------GCLVQYLPLLWKQSEEHNMLRCAILTTLIHLVQG-LGADSKNLYP 643

Query: 688 HLLQPVLWERTGNIPALVRLLQAFLERGSNTIASAAADKIPGLLGVFQK----LIASKAN 743
            LL  +      + P  V LL+  LE    T+ ++     P LL +FQ     L  S  N
Sbjct: 644 FLLPVIQLSTDVSQPPHVYLLEDGLELWLVTLENSPC-ITPELLRIFQNMSPLLELSSEN 702

Query: 744 DHQGFYLLNSIIEHMPPESVDQYRKQIFILLFQRLQNSKTTKFIKSFLVFINLYCIKYGA 803
               F ++N  I     E +  Y   +     + L+   T   ++   V  N   +K   
Sbjct: 703 LRTCFKIINGYIFLSSTEFLQTYAVGLCQSFCELLKEITTEGQVQVLKVVEN--ALKVNP 760

Query: 804 LALQEIFDGIQPKMFGMVLE 823
           +   ++F  I P +F  ++E
Sbjct: 761 ILGPQMFQPILPYVFKGIIE 780


>gi|21361659 importin 9 [Homo sapiens]
          Length = 1041

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 93/493 (18%), Positives = 200/493 (40%), Gaps = 61/493 (12%)

Query: 9   QTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLEKSQDNV-IKVCASVTFK 67
           + L + L   L P   +R  AE+ ++ +E  + + + L  L    Q  + I+  ASV  K
Sbjct: 23  EALVDTLTGILSPVQEVRAAAEEQIKVLEVTEEFGVHLAELTVDPQGALAIRQLASVILK 82

Query: 68  NYIKRNWRIVEDE--PNKICEADRVAIKANIVHLMLSSPEQIQKQLSDAISIIGREDFPQ 125
            Y++ +W    ++  P +  E  ++ I+  + + +  S  +++  ++ A+S I   D+P+
Sbjct: 83  QYVETHWCAQSEKFRPPETTERAKIVIRELLPNGLRESISKVRSSVAYAVSAIAHWDWPE 142

Query: 126 KWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLT 185
            WP L   ++    SGD + ++G +R           EF      T++ LV       + 
Sbjct: 143 AWPQLFNLLMEMLVSGDLNAVHGAMRVL--------TEFTREVTDTQMPLVAPVILPEMY 194

Query: 186 NLF-----------KATIELCSTHAN--------DASALRILFSSLI--LISKLFYSLNF 224
            +F              +E+ +T A+        +  A ++L   ++         +L  
Sbjct: 195 KIFTMAEVYGIRTRSRAVEIFTTCAHMICNMEELEKGAAKVLIFPVVQQFTEAFVQALQI 254

Query: 225 QDLPEFFEDNMETWMNNFHTLLTLDNKLLQTDDEEEAGLLELLKSQICDNAALYAQ---K 281
            D P          +     L+    K + +  ++   +L ++ + + ++AA Y +    
Sbjct: 255 PDGPTSDSGFKMEVLKAVTALVKNFPKHMVSSMQQ---ILPIVWNTLTESAAFYVRTEVN 311

Query: 282 YDEEFQRYLPRFVTAIWNLLVTTGQEVKYDLLVSNAIQFLASVCERPHYKNLFEDQNTLT 341
           Y EE +           + + + G+ + ++ LV +  +F+ ++ E   +K+    +  L 
Sbjct: 312 YTEEVE-----------DPVDSDGEVLGFENLVFSIFEFVHALLENSKFKSTV--KKALP 358

Query: 342 SICEKVIVPNMEFRAADEEAFEDNSEEYIRRDLEGSDIDTRRRAACDLVRGLCKFFEGPV 401
            +   +I+  M+      + +  N ++++  + + +   T R AA DL+  +   F+   
Sbjct: 359 ELIYYIIL-YMQITEEQIKVWTANPQQFVEDEDDDTFSYTVRIAAQDLLLAVATDFQNES 417

Query: 402 TGIFSGYVNSMLQ--EYAKNPSVN--WKHKDAAIYLVTSL-ASKAQTQKHGITQANELVN 456
               +      LQ  E  KN      WK  +A +  + S+ A    + K+G        +
Sbjct: 418 AAALAAAATRHLQEAEQTKNSGTEHWWKIHEACMLALGSVKAIITDSVKNGRIH----FD 473

Query: 457 LTEFFVNHILPDL 469
           +  F  N IL DL
Sbjct: 474 MHGFLTNVILADL 486


>gi|23510381 transportin 1 isoform 2 [Homo sapiens]
          Length = 890

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 68/325 (20%), Positives = 134/325 (41%), Gaps = 57/325 (17%)

Query: 5   DANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGN---QNYPLLLLTLLEKSQDNVIKVC 61
           +  LQ + + LK++  PD  I+R  ++ LE +       NY + +LT L KS+D   +  
Sbjct: 9   EQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKL-KSEDEPTRSL 67

Query: 62  ASVTFKNYIKRNWRIVEDEPNKICEADRVAIKANIVHLMLSSPEQIQKQLSDAISIIGRE 121
           + +  KN +K ++   ++ PN + +     IK+  ++ +  S   I+  +   I+ I  +
Sbjct: 68  SGLILKNNVKAHF---QNFPNGVTDF----IKSECLNNIGDSSPLIRATVGILITTIASK 120

Query: 122 DFPQKWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFA 181
              Q WPDLL ++ +   S D++   G       + +       S+ L   + +++  F 
Sbjct: 121 GELQNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNIMIPKF- 179

Query: 182 LPLTNLFKATIELCSTHA---------NDASALRILFSSLILISKLFYSLNFQDLPE--- 229
                 FK +     +HA         +   AL +   S I   +  ++L   + PE   
Sbjct: 180 ---LQFFKHSSPKIRSHAVACVNQFIISRTQALMLHIDSFI---ENLFALAGDEEPEVRK 233

Query: 230 --------FFEDNMETWMNNFHTLLTLDNKLLQTDDEEEAGLLE-------LLKSQICDN 274
                     E  M+  + + H +  ++  L +T D++E   LE       L +  IC +
Sbjct: 234 NVCRALVMLLEVRMDRLLPHMHNI--VEYMLQRTQDQDENVALEACEFWLTLAEQPICKD 291

Query: 275 AALYAQKYDEEFQRYLPRFVTAIWN 299
             +          R+LP+ +  + N
Sbjct: 292 VLV----------RHLPKLIPVLVN 306


>gi|133925811 transportin 1 isoform 1 [Homo sapiens]
          Length = 898

 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 68/325 (20%), Positives = 134/325 (41%), Gaps = 57/325 (17%)

Query: 5   DANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGN---QNYPLLLLTLLEKSQDNVIKVC 61
           +  LQ + + LK++  PD  I+R  ++ LE +       NY + +LT L KS+D   +  
Sbjct: 17  EQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKL-KSEDEPTRSL 75

Query: 62  ASVTFKNYIKRNWRIVEDEPNKICEADRVAIKANIVHLMLSSPEQIQKQLSDAISIIGRE 121
           + +  KN +K ++   ++ PN + +     IK+  ++ +  S   I+  +   I+ I  +
Sbjct: 76  SGLILKNNVKAHF---QNFPNGVTDF----IKSECLNNIGDSSPLIRATVGILITTIASK 128

Query: 122 DFPQKWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFA 181
              Q WPDLL ++ +   S D++   G       + +       S+ L   + +++  F 
Sbjct: 129 GELQNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNIMIPKF- 187

Query: 182 LPLTNLFKATIELCSTHA---------NDASALRILFSSLILISKLFYSLNFQDLPE--- 229
                 FK +     +HA         +   AL +   S I   +  ++L   + PE   
Sbjct: 188 ---LQFFKHSSPKIRSHAVACVNQFIISRTQALMLHIDSFI---ENLFALAGDEEPEVRK 241

Query: 230 --------FFEDNMETWMNNFHTLLTLDNKLLQTDDEEEAGLLE-------LLKSQICDN 274
                     E  M+  + + H +  ++  L +T D++E   LE       L +  IC +
Sbjct: 242 NVCRALVMLLEVRMDRLLPHMHNI--VEYMLQRTQDQDENVALEACEFWLTLAEQPICKD 299

Query: 275 AALYAQKYDEEFQRYLPRFVTAIWN 299
             +          R+LP+ +  + N
Sbjct: 300 VLV----------RHLPKLIPVLVN 314


>gi|209969838 transportin 2 (importin 3, karyopherin beta 2b)
           isoform 1 [Homo sapiens]
          Length = 897

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 38/179 (21%), Positives = 77/179 (43%), Gaps = 11/179 (6%)

Query: 5   DANLQTLTEYLKKTLDPDPAIRRPAE---KFLESVEGNQNYPLLLLTLLEKSQDNVIKVC 61
           +  LQ + + LK +  P+ A +R  +   K L       NY + +LT L KS+D   +  
Sbjct: 7   EQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRL-KSEDEPTRSL 65

Query: 62  ASVTFKNYIKRNWRIVEDEPNKICEADRVAIKANIVHLMLSSPEQIQKQLSDAISIIGRE 121
           + +  KN +K ++   +  P  + +     IK   ++ +  +   I+  +   I+ I  +
Sbjct: 66  SGLILKNNVKAHY---QSFPPPVADF----IKQECLNNIGDASSLIRATIGILITTIASK 118

Query: 122 DFPQKWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAF 180
              Q WP+LL ++ N   S D++   G       + +       S+ L   + +++  F
Sbjct: 119 GELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKF 177


>gi|209969836 transportin 2 (importin 3, karyopherin beta 2b)
           isoform 3 [Homo sapiens]
          Length = 887

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 38/179 (21%), Positives = 77/179 (43%), Gaps = 11/179 (6%)

Query: 5   DANLQTLTEYLKKTLDPDPAIRRPAE---KFLESVEGNQNYPLLLLTLLEKSQDNVIKVC 61
           +  LQ + + LK +  P+ A +R  +   K L       NY + +LT L KS+D   +  
Sbjct: 7   EQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRL-KSEDEPTRSL 65

Query: 62  ASVTFKNYIKRNWRIVEDEPNKICEADRVAIKANIVHLMLSSPEQIQKQLSDAISIIGRE 121
           + +  KN +K ++   +  P  + +     IK   ++ +  +   I+  +   I+ I  +
Sbjct: 66  SGLILKNNVKAHY---QSFPPPVADF----IKQECLNNIGDASSLIRATIGILITTIASK 118

Query: 122 DFPQKWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAF 180
              Q WP+LL ++ N   S D++   G       + +       S+ L   + +++  F
Sbjct: 119 GELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKF 177


>gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isoform
           2 [Homo sapiens]
          Length = 887

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 38/179 (21%), Positives = 77/179 (43%), Gaps = 11/179 (6%)

Query: 5   DANLQTLTEYLKKTLDPDPAIRRPAE---KFLESVEGNQNYPLLLLTLLEKSQDNVIKVC 61
           +  LQ + + LK +  P+ A +R  +   K L       NY + +LT L KS+D   +  
Sbjct: 7   EQGLQQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRL-KSEDEPTRSL 65

Query: 62  ASVTFKNYIKRNWRIVEDEPNKICEADRVAIKANIVHLMLSSPEQIQKQLSDAISIIGRE 121
           + +  KN +K ++   +  P  + +     IK   ++ +  +   I+  +   I+ I  +
Sbjct: 66  SGLILKNNVKAHY---QSFPPPVADF----IKQECLNNIGDASSLIRATIGILITTIASK 118

Query: 122 DFPQKWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAF 180
              Q WP+LL ++ N   S D++   G       + +       S+ L   + +++  F
Sbjct: 119 GELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKICEDSSELLDSDALNRPLNIMIPKF 177


>gi|22748937 exportin 5 [Homo sapiens]
          Length = 1204

 Score = 39.7 bits (91), Expect = 0.014
 Identities = 34/152 (22%), Positives = 69/152 (45%), Gaps = 17/152 (11%)

Query: 1   MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLL---LTLLEKSQDNV 57
           M+  +A  + L + +   +DP+   R   E      E  +  P+ +   L L EK+Q  +
Sbjct: 3   MDQVNALCEQLVKAVTVMMDPNSTQRYRLEALKFCEEFKEKCPICVPCGLRLAEKTQVAI 62

Query: 58  IKVCASVTFKNYIKRNWRIVEDEPNKICEADRVAIKANIVHLMLSSPEQI---QKQLSDA 114
           ++       ++ +K  W       N +   ++V +K +++ L+ +    I   +  + DA
Sbjct: 63  VRHFGLQILEHVVKFRW-------NGMSRLEKVYLKNSVMELIANGTLNILEEENHIKDA 115

Query: 115 ISIIGRE----DFPQKWPDLLTEMVNRFQSGD 142
           +S I  E    ++PQ WPD+L E+    + G+
Sbjct: 116 LSRIVVEMIKREWPQHWPDMLIELDTLSKQGE 147


>gi|4507943 exportin 1 [Homo sapiens]
          Length = 1071

 Score = 37.0 bits (84), Expect = 0.090
 Identities = 48/221 (21%), Positives = 98/221 (44%), Gaps = 24/221 (10%)

Query: 24  AIRRPAEKFLESVEGNQNYPLLLLTLLEKSQDNVIKVCASVTFKNYIKRNWRIVEDEPNK 83
           A +R A++ L  ++ + +    + T+LE SQ+   K       +N IK  W+I+   P  
Sbjct: 41  AQQRMAQEVLTHLKEHPDAWTRVDTILEFSQNMNTKYYGLQILENVIKTRWKIL---PRN 97

Query: 84  ICEADRVAIKANIVHLML---SSPEQIQKQ------LSDAISIIGREDFPQKWPDLLTEM 134
            CE     IK  +V L++   S P  ++K+      L+  +  I ++++P+ WP  ++++
Sbjct: 98  QCE----GIKKYVVGLIIKTSSDPTCVEKEKVYIGKLNMILVQILKQEWPKHWPTFISDI 153

Query: 135 VNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIEL 194
           V   ++ +    N ++     L      +F S ++ T++K         + N F    +L
Sbjct: 154 VGASRTSESLCQNNMV--ILKLLSEEVFDFSSGQI-TQVK--SKHLKDSMCNEFSQIFQL 208

Query: 195 CSTHANDASALRILFSSLILISKLFYSLNFQDLPEFFEDNM 235
           C     ++    ++ ++L     L   LN+  L   FE  +
Sbjct: 209 CQFVMENSQNAPLVHATL---ETLLRFLNWIPLGYIFETKL 246


>gi|46049063 exportin 6 [Homo sapiens]
          Length = 1125

 Score = 35.4 bits (80), Expect = 0.26
 Identities = 24/98 (24%), Positives = 48/98 (48%), Gaps = 11/98 (11%)

Query: 47  LTLLEKSQDNVIKVCASVTFKNYIKRNWRIVEDEPNKICEADRVAIKANIVHLMLSS--- 103
           L  L  ++++ + + +   F+N I + W  V  +       D++ I++ +  L+L+    
Sbjct: 49  LYFLSSTRNDYVMMYSLTVFENLINKMWLGVPSQ-------DKMEIRSCLPKLLLAHHKT 101

Query: 104 -PEQIQKQLSDAISIIGREDFPQKWPDLLTEMVNRFQS 140
            P  I+ +L   I  IGR+D+P  + D  T ++   QS
Sbjct: 102 LPYFIRNKLCKVIVDIGRQDWPMFYHDFFTNILQLIQS 139


>gi|21955154 NLR family, pyrin domain containing 12 isoform 2 [Homo
           sapiens]
          Length = 1061

 Score = 35.0 bits (79), Expect = 0.34
 Identities = 24/80 (30%), Positives = 44/80 (55%), Gaps = 12/80 (15%)

Query: 38  GNQNYPLLLLTLLEKSQDNVIKVCASVTFKNYIKRNWRIVEDEPNKICEADRVAIKANIV 97
           GNQ+  LL ++L+   +D         T+++Y++R +R++ED   ++ E   V +     
Sbjct: 107 GNQSTCLLEVSLVTPRKD------PQETYRDYVRRKFRLMEDRNARLGEC--VNLSHRYT 158

Query: 98  HLML----SSPEQIQKQLSD 113
            L+L    S+P Q+Q+QL D
Sbjct: 159 RLLLVKEHSNPMQVQQQLLD 178


>gi|189027129 phosphodiesterase 12 [Homo sapiens]
          Length = 609

 Score = 31.6 bits (70), Expect = 3.8
 Identities = 32/135 (23%), Positives = 55/135 (40%), Gaps = 20/135 (14%)

Query: 301 LVTTGQEVKYDLLVSNAIQFLASVCERPHYKNLFEDQNTLTSICEKVIVPNMEFRAADEE 360
           L T  ++ K+ LL  + I F  ++   P +K L E      S  EKV+  +   + +  +
Sbjct: 382 LATFYRKSKFSLLSQHDISFYEALESDPLHKELLEKLVLYPSAQEKVLQRSSVLQVSVLQ 441

Query: 361 AFEDNSEE---------------YIRRDLEGSDIDTRRRAACDLVRGLCKFFEG-----P 400
           + +D+S+                YIR       +   R  +CDL  G+   F G     P
Sbjct: 442 STKDSSKRICVANTHLYWHPKGGYIRLIQMAVALAHIRHVSCDLYPGIPVIFCGDFNSTP 501

Query: 401 VTGIFSGYVNSMLQE 415
            TG++   +N  + E
Sbjct: 502 STGMYHFVINGSIPE 516


>gi|62460637 importin 4 [Homo sapiens]
          Length = 1081

 Score = 31.2 bits (69), Expect = 4.9
 Identities = 26/105 (24%), Positives = 50/105 (47%), Gaps = 15/105 (14%)

Query: 504 IPLLINHLQAESIVVHTY----AAHALERLFTMRGPNNATLFTAAEIAPFVEILLTNLFK 559
           +PLL+ +L++  +  HT+    A +ALE      GP         ++ P++  L+  + +
Sbjct: 437 MPLLLAYLKSVPLG-HTHHLAKACYALENFVENLGP---------KVQPYLPELMECMLQ 486

Query: 560 ALTLPGSSE-NEYIMKAIMRSFSLLQEAIIPYIPTLITQLTQKLL 603
            L  P S    E  + A+    +  Q +++PY P ++  L + LL
Sbjct: 487 LLRNPSSPRAKELAVSALGAIATAAQASLLPYFPAIMEHLREFLL 531


>gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo
           sapiens]
          Length = 581

 Score = 30.8 bits (68), Expect = 6.4
 Identities = 26/87 (29%), Positives = 46/87 (52%), Gaps = 10/87 (11%)

Query: 654 NDVQEFI-PYVFQ----VMSLLLETHK-----NDIPSSYMALFPHLLQPVLWERTGNIPA 703
           N+++ F  P VFQ    +  L L+++K      +I  S+++L    L   +WE + NI +
Sbjct: 263 NEIEAFSGPSVFQCVPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGNIWECSRNICS 322

Query: 704 LVRLLQAFLERGSNTIASAAADKIPGL 730
           LV  L++F     NTI  A+  ++ G+
Sbjct: 323 LVNWLKSFKGLRENTIICASPKELQGV 349


>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
           sapiens]
          Length = 376

 Score = 30.4 bits (67), Expect = 8.4
 Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 7/91 (7%)

Query: 76  IVEDEPNKICEADRVAIKANIVHLMLSSPEQIQKQLSDAISIIGREDFPQKWPDLLTEMV 135
           + +D P+       V+I + +  ++L +      Q++ A+S+   ED  + +  LLTE V
Sbjct: 19  LCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSLNTEEDIHRAFQSLLTE-V 77

Query: 136 NRFQSGDFHVINGVLRTAHSLFKRYRHEFKS 166
           N+  +        +LRTA+ LF     +F S
Sbjct: 78  NKAGT------QYLLRTANRLFGEKTCQFLS 102


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,996,430
Number of Sequences: 37866
Number of extensions: 1419922
Number of successful extensions: 3528
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 3503
Number of HSP's gapped (non-prelim): 34
length of query: 971
length of database: 18,247,518
effective HSP length: 112
effective length of query: 859
effective length of database: 14,006,526
effective search space: 12031605834
effective search space used: 12031605834
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.