BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens] (696 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens] 1425 0.0 gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo... 973 0.0 gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo... 973 0.0 gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo... 973 0.0 gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Ra... 130 5e-30 gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho famil... 129 7e-30 gi|115430108 rho-related BTB domain containing 3 [Homo sapiens] 127 3e-29 gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo sapi... 126 8e-29 gi|46249393 ras homolog gene family, member G [Homo sapiens] 123 7e-28 gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens] 122 1e-27 gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens] 122 1e-27 gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens] 122 1e-27 gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Ra... 119 7e-27 gi|10835049 ras homolog gene family, member A [Homo sapiens] 117 3e-26 gi|50263042 ras-like protein TC10 [Homo sapiens] 112 2e-24 gi|111494251 ras homolog gene family, member C precursor [Homo s... 108 1e-23 gi|111494248 ras homolog gene family, member C precursor [Homo s... 108 1e-23 gi|28395033 ras homolog gene family, member C precursor [Homo sa... 108 1e-23 gi|7656900 ras homolog D [Homo sapiens] 108 2e-23 gi|4757764 ras homolog gene family, member B [Homo sapiens] 103 4e-22 gi|11034843 ras homolog gene family, member U [Homo sapiens] 102 9e-22 gi|229577148 ras homolog gene family, member V [Homo sapiens] 101 2e-21 gi|16903164 ras homolog gene family, member J [Homo sapiens] 98 2e-20 gi|7657514 GTP-binding protein RHO6 [Homo sapiens] 93 7e-19 gi|4885581 Rho family GTPase 2 [Homo sapiens] 91 5e-18 gi|4757770 ras homolog gene family, member H [Homo sapiens] 88 3e-17 gi|4885069 ras homolog gene family, member E [Homo sapiens] 87 5e-17 gi|38016957 ras homolog gene family, member F [Homo sapiens] 83 8e-16 gi|7549817 RAB, member of RAS oncogene family-like 2A [Homo sapi... 56 1e-07 gi|5902038 RAB, member of RAS oncogene family-like 2A [Homo sapi... 56 1e-07 >gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens] Length = 696 Score = 1425 bits (3689), Expect = 0.0 Identities = 696/696 (100%), Positives = 696/696 (100%) Query: 1 MDADMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYR 60 MDADMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYR Sbjct: 1 MDADMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYR 60 Query: 61 VCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKS 120 VCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKS Sbjct: 61 VCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKS 120 Query: 121 MWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKE 180 MWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKE Sbjct: 121 MWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKE 180 Query: 181 LGLPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPP 240 LGLPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPP Sbjct: 181 LGLPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPP 240 Query: 241 PVIKIPECPSMGTNEAACLLDNPLCADVLFILQDQEHIFAHRIYLATSSSKFYDLFLMEC 300 PVIKIPECPSMGTNEAACLLDNPLCADVLFILQDQEHIFAHRIYLATSSSKFYDLFLMEC Sbjct: 241 PVIKIPECPSMGTNEAACLLDNPLCADVLFILQDQEHIFAHRIYLATSSSKFYDLFLMEC 300 Query: 301 EESPNGSEGACEKEKQSRDFQGRILSVDPEEEREEGPPRIPQADQWKSSNKSLVEALGLE 360 EESPNGSEGACEKEKQSRDFQGRILSVDPEEEREEGPPRIPQADQWKSSNKSLVEALGLE Sbjct: 301 EESPNGSEGACEKEKQSRDFQGRILSVDPEEEREEGPPRIPQADQWKSSNKSLVEALGLE 360 Query: 361 AEGAVPETQTLTGWSKGFIGMHREMQVNPISKRMGPMTVVRMDASVQPGPFRTLLQFLYT 420 AEGAVPETQTLTGWSKGFIGMHREMQVNPISKRMGPMTVVRMDASVQPGPFRTLLQFLYT Sbjct: 361 AEGAVPETQTLTGWSKGFIGMHREMQVNPISKRMGPMTVVRMDASVQPGPFRTLLQFLYT 420 Query: 421 GQLDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMNQEITKAFHVRKANRIKECLS 480 GQLDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMNQEITKAFHVRKANRIKECLS Sbjct: 421 GQLDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMNQEITKAFHVRKANRIKECLS 480 Query: 481 KGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVESANSEVYLPNINKISMQAVL 540 KGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVESANSEVYLPNINKISMQAVL Sbjct: 481 KGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVESANSEVYLPNINKISMQAVL 540 Query: 541 DYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQELTKAATSGVGIDGEVLSY 600 DYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQELTKAATSGVGIDGEVLSY Sbjct: 541 DYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQELTKAATSGVGIDGEVLSY 600 Query: 601 LELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSADNQEYFERHRWPPVWYLKEE 660 LELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSADNQEYFERHRWPPVWYLKEE Sbjct: 601 LELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSADNQEYFERHRWPPVWYLKEE 660 Query: 661 DHYQRVKREREKEDIALNKHRSRRKWCFWNSSPAVA 696 DHYQRVKREREKEDIALNKHRSRRKWCFWNSSPAVA Sbjct: 661 DHYQRVKREREKEDIALNKHRSRRKWCFWNSSPAVA 696 >gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo sapiens] Length = 727 Score = 973 bits (2516), Expect = 0.0 Identities = 483/710 (68%), Positives = 563/710 (79%), Gaps = 23/710 (3%) Query: 1 MDADMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYR 60 MD+DMDYERPNVETIKCVVVGDNAVGKTRLICARACN TLTQYQLLATHVPTVWAIDQYR Sbjct: 1 MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR 60 Query: 61 VCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKS 120 VCQEVLERSRDVVD+VSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSL+HVK+ Sbjct: 61 VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT 120 Query: 121 MWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKE 180 MWYPEIKHFCPR PVILVGCQLDLRYADLEAVNRARRPLARPIK +ILPPEKGREVAKE Sbjct: 121 MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE 180 Query: 181 LGLPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPP 240 LG+PYYETSV QFGIKDVFDNAIRAALISRRHLQFWKSHL+ VQ+PLLQAPFLPPK PP Sbjct: 181 LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP 240 Query: 241 PVIKIPECPSMGTNEAACLLDNPLCADVLFILQDQEHIFAHRIYLATSSSKFYDLFLMEC 300 P+I +P+ PS A LL++PLCADV+ +LQ++ IFAH+IYL+TSSSKFYDLFLM+ Sbjct: 241 PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL 300 Query: 301 EES------------PNGSEGACEK------EKQSRDFQGRILSVDPEEEREEGPPRIPQ 342 E P +G ++ RDF R S D E +E P Sbjct: 301 SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGP- 359 Query: 343 ADQWKSSNKSLVEALGLEAEGAVP-ETQTLTGWSKGFIGMHREMQVNPISKRMGPMTVVR 401 A S++ ++ G G +P + L+ WS+ F+ + EM +P++ + M VV+ Sbjct: 360 AGLRASTSDGILRGNG---TGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVK 416 Query: 402 MDASVQPGPFRTLLQFLYTGQLDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMNQ 461 MD+S+QPGPFR +L++LYTG+LDE E+DL+ +A IAE+LE+FDLRMMV NI+N EAFMNQ Sbjct: 417 MDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQ 476 Query: 462 EITKAFHVRKANRIKECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVES 521 EITKAFHVR+ NR+KECL+KGTFSDVTF LDDG ISAHKPLLI SC+WMAAMFGG FVES Sbjct: 477 EITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVES 536 Query: 522 ANSEVYLPNINKISMQAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQ 581 + EV P +K M+AVL+YLYT + + DLD ++LI LANR CLPHLVAL EQ+ V Sbjct: 537 STREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVT 596 Query: 582 ELTKAATSGVGIDGEVLSYLELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSAD 641 L +A V IDG+VL +LELAQFH A+QLA WCLHHICTNYN+VC KF +++K+ S + Sbjct: 597 GLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPE 656 Query: 642 NQEYFERHRWPPVWYLKEEDHYQRVKREREKEDIALNKHRSRRKWCFWNS 691 NQEYFE+HRWPPVWYLKEEDHYQR ++EREKED K + +R+W FWNS Sbjct: 657 NQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNS 706 >gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo sapiens] Length = 734 Score = 973 bits (2516), Expect = 0.0 Identities = 483/710 (68%), Positives = 563/710 (79%), Gaps = 23/710 (3%) Query: 1 MDADMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYR 60 MD+DMDYERPNVETIKCVVVGDNAVGKTRLICARACN TLTQYQLLATHVPTVWAIDQYR Sbjct: 8 MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR 67 Query: 61 VCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKS 120 VCQEVLERSRDVVD+VSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSL+HVK+ Sbjct: 68 VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT 127 Query: 121 MWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKE 180 MWYPEIKHFCPR PVILVGCQLDLRYADLEAVNRARRPLARPIK +ILPPEKGREVAKE Sbjct: 128 MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE 187 Query: 181 LGLPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPP 240 LG+PYYETSV QFGIKDVFDNAIRAALISRRHLQFWKSHL+ VQ+PLLQAPFLPPK PP Sbjct: 188 LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP 247 Query: 241 PVIKIPECPSMGTNEAACLLDNPLCADVLFILQDQEHIFAHRIYLATSSSKFYDLFLMEC 300 P+I +P+ PS A LL++PLCADV+ +LQ++ IFAH+IYL+TSSSKFYDLFLM+ Sbjct: 248 PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL 307 Query: 301 EES------------PNGSEGACEK------EKQSRDFQGRILSVDPEEEREEGPPRIPQ 342 E P +G ++ RDF R S D E +E P Sbjct: 308 SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGP- 366 Query: 343 ADQWKSSNKSLVEALGLEAEGAVP-ETQTLTGWSKGFIGMHREMQVNPISKRMGPMTVVR 401 A S++ ++ G G +P + L+ WS+ F+ + EM +P++ + M VV+ Sbjct: 367 AGLRASTSDGILRGNG---TGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVK 423 Query: 402 MDASVQPGPFRTLLQFLYTGQLDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMNQ 461 MD+S+QPGPFR +L++LYTG+LDE E+DL+ +A IAE+LE+FDLRMMV NI+N EAFMNQ Sbjct: 424 MDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQ 483 Query: 462 EITKAFHVRKANRIKECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVES 521 EITKAFHVR+ NR+KECL+KGTFSDVTF LDDG ISAHKPLLI SC+WMAAMFGG FVES Sbjct: 484 EITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVES 543 Query: 522 ANSEVYLPNINKISMQAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQ 581 + EV P +K M+AVL+YLYT + + DLD ++LI LANR CLPHLVAL EQ+ V Sbjct: 544 STREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVT 603 Query: 582 ELTKAATSGVGIDGEVLSYLELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSAD 641 L +A V IDG+VL +LELAQFH A+QLA WCLHHICTNYN+VC KF +++K+ S + Sbjct: 604 GLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPE 663 Query: 642 NQEYFERHRWPPVWYLKEEDHYQRVKREREKEDIALNKHRSRRKWCFWNS 691 NQEYFE+HRWPPVWYLKEEDHYQR ++EREKED K + +R+W FWNS Sbjct: 664 NQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNS 713 >gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo sapiens] Length = 749 Score = 973 bits (2516), Expect = 0.0 Identities = 483/710 (68%), Positives = 563/710 (79%), Gaps = 23/710 (3%) Query: 1 MDADMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYR 60 MD+DMDYERPNVETIKCVVVGDNAVGKTRLICARACN TLTQYQLLATHVPTVWAIDQYR Sbjct: 23 MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYR 82 Query: 61 VCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKS 120 VCQEVLERSRDVVD+VSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSL+HVK+ Sbjct: 83 VCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKT 142 Query: 121 MWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKE 180 MWYPEIKHFCPR PVILVGCQLDLRYADLEAVNRARRPLARPIK +ILPPEKGREVAKE Sbjct: 143 MWYPEIKHFCPRAPVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKE 202 Query: 181 LGLPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPP 240 LG+PYYETSV QFGIKDVFDNAIRAALISRRHLQFWKSHL+ VQ+PLLQAPFLPPK PP Sbjct: 203 LGIPYYETSVVAQFGIKDVFDNAIRAALISRRHLQFWKSHLRNVQRPLLQAPFLPPKPPP 262 Query: 241 PVIKIPECPSMGTNEAACLLDNPLCADVLFILQDQEHIFAHRIYLATSSSKFYDLFLMEC 300 P+I +P+ PS A LL++PLCADV+ +LQ++ IFAH+IYL+TSSSKFYDLFLM+ Sbjct: 263 PIIVVPDPPSSSEECPAHLLEDPLCADVILVLQERVRIFAHKIYLSTSSSKFYDLFLMDL 322 Query: 301 EES------------PNGSEGACEK------EKQSRDFQGRILSVDPEEEREEGPPRIPQ 342 E P +G ++ RDF R S D E +E P Sbjct: 323 SEGELGGPSEPGGTHPEDHQGHSDQHHHHHHHHHGRDFLLRAASFDVCESVDEAGGSGP- 381 Query: 343 ADQWKSSNKSLVEALGLEAEGAVP-ETQTLTGWSKGFIGMHREMQVNPISKRMGPMTVVR 401 A S++ ++ G G +P + L+ WS+ F+ + EM +P++ + M VV+ Sbjct: 382 AGLRASTSDGILRGNG---TGYLPGRGRVLSSWSRAFVSIQEEMAEDPLTYKSRLMVVVK 438 Query: 402 MDASVQPGPFRTLLQFLYTGQLDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMNQ 461 MD+S+QPGPFR +L++LYTG+LDE E+DL+ +A IAE+LE+FDLRMMV NI+N EAFMNQ Sbjct: 439 MDSSIQPGPFRAVLKYLYTGELDENERDLMHIAHIAELLEVFDLRMMVANILNNEAFMNQ 498 Query: 462 EITKAFHVRKANRIKECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVES 521 EITKAFHVR+ NR+KECL+KGTFSDVTF LDDG ISAHKPLLI SC+WMAAMFGG FVES Sbjct: 499 EITKAFHVRRTNRVKECLAKGTFSDVTFILDDGTISAHKPLLISSCDWMAAMFGGPFVES 558 Query: 522 ANSEVYLPNINKISMQAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQ 581 + EV P +K M+AVL+YLYT + + DLD ++LI LANR CLPHLVAL EQ+ V Sbjct: 559 STREVVFPYTSKSCMRAVLEYLYTGMFTSSPDLDDMKLIILANRLCLPHLVALTEQYTVT 618 Query: 582 ELTKAATSGVGIDGEVLSYLELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSAD 641 L +A V IDG+VL +LELAQFH A+QLA WCLHHICTNYN+VC KF +++K+ S + Sbjct: 619 GLMEATQMMVDIDGDVLVFLELAQFHCAYQLADWCLHHICTNYNNVCRKFPRDMKAMSPE 678 Query: 642 NQEYFERHRWPPVWYLKEEDHYQRVKREREKEDIALNKHRSRRKWCFWNS 691 NQEYFE+HRWPPVWYLKEEDHYQR ++EREKED K + +R+W FWNS Sbjct: 679 NQEYFEKHRWPPVWYLKEEDHYQRARKEREKEDYLHLKRQPKRRWLFWNS 728 >gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Rac1 [Homo sapiens] Length = 192 Score = 130 bits (326), Expect = 5e-30 Identities = 80/200 (40%), Positives = 115/200 (57%), Gaps = 26/200 (13%) Query: 12 VETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71 ++ IKCVVVGD AVGKT L+ + N +Y +PTV+ D Y + Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44 Query: 72 VVDEVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHF 129 +VD V+L LWDT G D+ + R +Y ++DV ++CFS+ +P S +V++ WYPE++H Sbjct: 45 MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHH 104 Query: 130 CPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELG-LPYYET 188 CP TP+ILVG +LDLR D + + + + PI +G +AKE+G + Y E Sbjct: 105 CPNTPIILVGTKLDLR-DDKDTIEKLKEKKLTPITY------PQGLAMAKEIGAVKYLEC 157 Query: 189 SVFDQFGIKDVFDNAIRAAL 208 S Q G+K VFD AIRA L Sbjct: 158 SALTQRGLKTVFDEAIRAVL 177 >gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) [Homo sapiens] Length = 192 Score = 129 bits (325), Expect = 7e-30 Identities = 80/200 (40%), Positives = 115/200 (57%), Gaps = 26/200 (13%) Query: 12 VETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71 ++ IKCVVVGD AVGKT L+ + N +Y +PTV+ D Y + Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44 Query: 72 VVDEVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHF 129 +VD V+L LWDT G D+ + R +Y ++DV ++CFS+ +P S +V++ WYPE++H Sbjct: 45 MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHH 104 Query: 130 CPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELG-LPYYET 188 CP TP++LVG +LDLR D + + R R PI +G +A+E+G + Y E Sbjct: 105 CPHTPILLVGTKLDLR-DDKDTIERLRDKKLAPITY------PQGLAMAREIGSVKYLEC 157 Query: 189 SVFDQFGIKDVFDNAIRAAL 208 S Q G+K VFD AIRA L Sbjct: 158 SALTQRGLKTVFDEAIRAVL 177 >gi|115430108 rho-related BTB domain containing 3 [Homo sapiens] Length = 611 Score = 127 bits (319), Expect = 3e-29 Identities = 140/610 (22%), Positives = 254/610 (41%), Gaps = 99/610 (16%) Query: 82 LWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHFCPRTPVILVGCQ 141 +WD F R G +D++V+ +++ + S + VK + P IK PVI+ Sbjct: 75 VWDIFDSDWYTSRNLIGGADIIVIKYNVNDKFSFHEVKDNYIPVIKRALNSVPVII---- 130 Query: 142 LDLRYADLEAVNRARRPLARPI---KRGDILPPEKGREVAKELGLPYYETSVFDQFGIKD 198 A + P P+ RG + +G ++AKELG Y E D F I Sbjct: 131 -----AAVGTRQNEELPCTCPLCTSDRGSCVSTTEGIQLAKELGATYLELHSLDDFYIGK 185 Query: 199 VFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPPPVIKIPECPSMGTNEAAC 258 F + +I + + +K++K + F + PP ++ PE + EA+ Sbjct: 186 YFGGVLEYFMIQALN----QKTSEKMKKRKMSNSFHGIR--PPQLEQPEKMPVLKAEASH 239 Query: 259 L---LDNPL----CADVLFILQDQEHIF-AHRIYLATSSSKFYDLFLMECEESPNGSEGA 310 L+N L C DV+F + + + AH+I L S F LF + Sbjct: 240 YNSDLNNLLFCCQCVDVVFYNPNLKKVVEAHKIVLCAVSHVFMLLFNV------------ 287 Query: 311 CEKEKQSRDFQGRILSVDPEEEREEGPPRIPQADQWKSSNKSLVEALGLEAEGAVPETQT 370 + P Q S ++ + + + A P Sbjct: 288 ----------------------------KSPTDIQDSSIIRTTQDLFAINRDTAFP---- 315 Query: 371 LTGWSKGFIGMHREMQVNPISKRMGPMTVVRMDASVQPGPFRTLLQFLYTG--QLDEKEK 428 G E NP P+ V+ DA + +L+F+Y+G Q +E E+ Sbjct: 316 ---------GASHESSGNP------PLRVIVKDA-LFCSCLSDILRFIYSGAFQWEELEE 359 Query: 429 DLVGLAQIAEVLEMFDLRMMVENIMNKEAFMN-QEITKAFHVRKA-----NRIKECLSKG 482 D+ ++ + ++ ++ V+ I+ +N K + RK +K L+K Sbjct: 360 DI--RKKLKDSGDVSNVIEKVKCILKTPGKINCLRNCKTYQARKPLWFYNTSLKFFLNKP 417 Query: 483 TFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVESANSEVYLPNINKISMQAVLDY 542 +DV F++ + AH+ +L+ CE MAAMF G+++E+ + + + ++K + + L+Y Sbjct: 418 MLADVVFEIQGTTVPAHRAILVARCEVMAAMFNGNYMEAKSVLIPVYGVSKETFLSFLEY 477 Query: 543 LYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQELTKAATSGV-GIDGEVLSYL 601 LYT P + L+ A + + L + E + +L + + ++ +++ L Sbjct: 478 LYTDSCCPAGIFQAMCLLICAEMYQVSRLQHICELFIITQLQSMPSRELASMNLDIVDLL 537 Query: 602 ELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSADNQEYFERHRWPPVWYLKEED 661 + A+FH++ L+ W LH I TNY K E + S + + + E+HRWP YLK+ Sbjct: 538 KKAKFHHSDCLSTWLLHFIATNYLIFSQK--PEFQDLSVEERSFVEKHRWPSNMYLKQLA 595 Query: 662 HYQRVKRERE 671 Y++ R+ Sbjct: 596 EYRKYIHSRK 605 >gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo sapiens] Length = 192 Score = 126 bits (316), Expect = 8e-29 Identities = 78/200 (39%), Positives = 114/200 (57%), Gaps = 26/200 (13%) Query: 12 VETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71 ++ IKCVVVGD AVGKT L+ + N +Y +PTV+ D Y + Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44 Query: 72 VVDEVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHF 129 +VD V+L LWDT G D+ + R +Y ++DV ++CFS+ +P S +V++ W+PE++H Sbjct: 45 MVDSKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHH 104 Query: 130 CPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKEL-GLPYYET 188 CP TP+ILVG +LDLR D + + + + PI +G +AKE+ + Y E Sbjct: 105 CPSTPIILVGTKLDLR-DDKDTIEKLKEKKLAPITY------PQGLALAKEIDSVKYLEC 157 Query: 189 SVFDQFGIKDVFDNAIRAAL 208 S Q G+K VFD AIRA L Sbjct: 158 SALTQRGLKTVFDEAIRAVL 177 >gi|46249393 ras homolog gene family, member G [Homo sapiens] Length = 191 Score = 123 bits (308), Expect = 7e-28 Identities = 76/200 (38%), Positives = 113/200 (56%), Gaps = 26/200 (13%) Query: 12 VETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71 +++IKCVVVGD AVGKT L+ N +Y +PTV+ D Y ++ Sbjct: 1 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEY------IPTVF--DNYS--------AQS 44 Query: 72 VVDEVSVSLRLWDTFGDHHKDR--RFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHF 129 VD +V+L LWDT G DR +Y +++V V+CFSIA+P S +V+ W+PE+ H Sbjct: 45 AVDGRTVNLNLWDTAGQEEYDRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHH 104 Query: 130 CPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKEL-GLPYYET 188 CP P++LVG + DLR A + + R + PI P++G+ +AK++ + Y E Sbjct: 105 CPDVPILLVGTKKDLR-AQPDTLRRLKEQGQAPI------TPQQGQALAKQIHAVRYLEC 157 Query: 189 SVFDQFGIKDVFDNAIRAAL 208 S Q G+K+VF A+RA L Sbjct: 158 SALQQDGVKEVFAEAVRAVL 177 >gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens] Length = 191 Score = 122 bits (305), Expect = 1e-27 Identities = 78/200 (39%), Positives = 114/200 (57%), Gaps = 26/200 (13%) Query: 12 VETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71 ++TIKCVVVGD AVGKT L+ + N ++Y VPTV+ D Y V Sbjct: 1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEY------VPTVF--DNYAVTV-------- 44 Query: 72 VVDEVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHF 129 ++ +L L+DT G D+ + R +Y ++DV ++CFS+ +P+S +VK W PEI H Sbjct: 45 MIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHH 104 Query: 130 CPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKEL-GLPYYET 188 CP+TP +LVG Q+DLR D + + + +PI PE ++A++L + Y E Sbjct: 105 CPKTPFLLVGTQIDLR-DDPSTIEKLAKNKQKPI------TPETAEKLARDLKAVKYVEC 157 Query: 189 SVFDQFGIKDVFDNAIRAAL 208 S Q G+K+VFD AI AAL Sbjct: 158 SALTQRGLKNVFDEAILAAL 177 >gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens] Length = 191 Score = 122 bits (305), Expect = 1e-27 Identities = 78/200 (39%), Positives = 114/200 (57%), Gaps = 26/200 (13%) Query: 12 VETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71 ++TIKCVVVGD AVGKT L+ + N ++Y VPTV+ D Y V Sbjct: 1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEY------VPTVF--DNYAVTV-------- 44 Query: 72 VVDEVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHF 129 ++ +L L+DT G D+ + R +Y ++DV ++CFS+ +P+S +VK W PEI H Sbjct: 45 MIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHH 104 Query: 130 CPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKEL-GLPYYET 188 CP+TP +LVG Q+DLR D + + + +PI PE ++A++L + Y E Sbjct: 105 CPKTPFLLVGTQIDLR-DDPSTIEKLAKNKQKPI------TPETAEKLARDLKAVKYVEC 157 Query: 189 SVFDQFGIKDVFDNAIRAAL 208 S Q G+K+VFD AI AAL Sbjct: 158 SALTQKGLKNVFDEAILAAL 177 >gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens] Length = 191 Score = 122 bits (305), Expect = 1e-27 Identities = 78/200 (39%), Positives = 114/200 (57%), Gaps = 26/200 (13%) Query: 12 VETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71 ++TIKCVVVGD AVGKT L+ + N ++Y VPTV+ D Y V Sbjct: 1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEY------VPTVF--DNYAVTV-------- 44 Query: 72 VVDEVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHF 129 ++ +L L+DT G D+ + R +Y ++DV ++CFS+ +P+S +VK W PEI H Sbjct: 45 MIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHH 104 Query: 130 CPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKEL-GLPYYET 188 CP+TP +LVG Q+DLR D + + + +PI PE ++A++L + Y E Sbjct: 105 CPKTPFLLVGTQIDLR-DDPSTIEKLAKNKQKPI------TPETAEKLARDLKAVKYVEC 157 Query: 189 SVFDQFGIKDVFDNAIRAAL 208 S Q G+K+VFD AI AAL Sbjct: 158 SALTQKGLKNVFDEAILAAL 177 >gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Rac1b [Homo sapiens] Length = 211 Score = 119 bits (299), Expect = 7e-27 Identities = 81/219 (36%), Positives = 113/219 (51%), Gaps = 45/219 (20%) Query: 12 VETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71 ++ IKCVVVGD AVGKT L+ + N +Y +PTV+ D Y + Sbjct: 1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNYS--------ANV 44 Query: 72 VVDEVSVSLRLWDTFGDHHKDRRF----------AYGR-----------SDVVVLCFSIA 110 +VD V+L LWDT G DR YG+ +DV ++CFS+ Sbjct: 45 MVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLV 104 Query: 111 NPNSLNHVKSMWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILP 170 +P S +V++ WYPE++H CP TP+ILVG +LDLR D + + + + PI Sbjct: 105 SPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLR-DDKDTIEKLKEKKLTPITY----- 158 Query: 171 PEKGREVAKELG-LPYYETSVFDQFGIKDVFDNAIRAAL 208 +G +AKE+G + Y E S Q G+K VFD AIRA L Sbjct: 159 -PQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVL 196 >gi|10835049 ras homolog gene family, member A [Homo sapiens] Length = 193 Score = 117 bits (294), Expect = 3e-26 Identities = 77/200 (38%), Positives = 113/200 (56%), Gaps = 26/200 (13%) Query: 16 KCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDE 75 K V+VGD A GKT L+ ++ Q +VPTV+ + Y EV D Sbjct: 7 KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYVADIEV--------DG 50 Query: 76 VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHFCPRT 133 V L LWDT G D+ + R +Y +DV+++CFSI +P+SL ++ W PE+KHFCP Sbjct: 51 KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110 Query: 134 PVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELG-LPYYETSVFD 192 P+ILVG + DLR + RR LA+ + + + PE+GR++A +G Y E S Sbjct: 111 PIILVGNKKDLRNDE-----HTRRELAK--MKQEPVKPEEGRDMANRIGAFGYMECSAKT 163 Query: 193 QFGIKDVFDNAIRAALISRR 212 + G+++VF+ A RAAL +RR Sbjct: 164 KDGVREVFEMATRAALQARR 183 >gi|50263042 ras-like protein TC10 [Homo sapiens] Length = 205 Score = 112 bits (279), Expect = 2e-24 Identities = 78/207 (37%), Positives = 110/207 (53%), Gaps = 26/207 (12%) Query: 10 PNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERS 69 P +KCVVVGD AVGKT L+ + A + +Y VPTV+ D Y V V + Sbjct: 5 PGALMLKCVVVGDGAVGKTCLLMSYANDAFPEEY------VPTVF--DHYAVSVTVGGKQ 56 Query: 70 RDVVDEVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIK 127 L L+DT G D+ + R +Y +DV ++CFS+ NP S +VK W PE+K Sbjct: 57 --------YLLGLYDTAGQEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELK 108 Query: 128 HFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELG-LPYY 186 + P P +L+G Q+DLR D + + R +PI E+G+++AKE+G Y Sbjct: 109 EYAPNVPFLLIGTQIDLR-DDPKTLARLNDMKEKPI------CVEQGQKLAKEIGACCYV 161 Query: 187 ETSVFDQFGIKDVFDNAIRAALISRRH 213 E S Q G+K VFD AI A L ++H Sbjct: 162 ECSALTQKGLKTVFDEAIIAILTPKKH 188 >gi|111494251 ras homolog gene family, member C precursor [Homo sapiens] Length = 193 Score = 108 bits (271), Expect = 1e-23 Identities = 73/201 (36%), Positives = 110/201 (54%), Gaps = 26/201 (12%) Query: 16 KCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDE 75 K V+VGD A GKT L+ ++ Q +VPTV+ + Y EV D Sbjct: 7 KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYIADIEV--------DG 50 Query: 76 VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHFCPRT 133 V L LWDT G D+ + R +Y +DV+++CFSI +P+SL ++ W PE+KHFCP Sbjct: 51 KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110 Query: 134 PVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKEL-GLPYYETSVFD 192 P+ILVG + DLR + RR LA+ + + + E+GR++A + Y E S Sbjct: 111 PIILVGNKKDLRQDE-----HTRRELAK--MKQEPVRSEEGRDMANRISAFGYLECSAKT 163 Query: 193 QFGIKDVFDNAIRAALISRRH 213 + G+++VF+ A RA L R++ Sbjct: 164 KEGVREVFEMATRAGLQVRKN 184 >gi|111494248 ras homolog gene family, member C precursor [Homo sapiens] Length = 193 Score = 108 bits (271), Expect = 1e-23 Identities = 73/201 (36%), Positives = 110/201 (54%), Gaps = 26/201 (12%) Query: 16 KCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDE 75 K V+VGD A GKT L+ ++ Q +VPTV+ + Y EV D Sbjct: 7 KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYIADIEV--------DG 50 Query: 76 VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHFCPRT 133 V L LWDT G D+ + R +Y +DV+++CFSI +P+SL ++ W PE+KHFCP Sbjct: 51 KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110 Query: 134 PVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKEL-GLPYYETSVFD 192 P+ILVG + DLR + RR LA+ + + + E+GR++A + Y E S Sbjct: 111 PIILVGNKKDLRQDE-----HTRRELAK--MKQEPVRSEEGRDMANRISAFGYLECSAKT 163 Query: 193 QFGIKDVFDNAIRAALISRRH 213 + G+++VF+ A RA L R++ Sbjct: 164 KEGVREVFEMATRAGLQVRKN 184 >gi|28395033 ras homolog gene family, member C precursor [Homo sapiens] Length = 193 Score = 108 bits (271), Expect = 1e-23 Identities = 73/201 (36%), Positives = 110/201 (54%), Gaps = 26/201 (12%) Query: 16 KCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDE 75 K V+VGD A GKT L+ ++ Q +VPTV+ + Y EV D Sbjct: 7 KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYIADIEV--------DG 50 Query: 76 VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHFCPRT 133 V L LWDT G D+ + R +Y +DV+++CFSI +P+SL ++ W PE+KHFCP Sbjct: 51 KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110 Query: 134 PVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKEL-GLPYYETSVFD 192 P+ILVG + DLR + RR LA+ + + + E+GR++A + Y E S Sbjct: 111 PIILVGNKKDLRQDE-----HTRRELAK--MKQEPVRSEEGRDMANRISAFGYLECSAKT 163 Query: 193 QFGIKDVFDNAIRAALISRRH 213 + G+++VF+ A RA L R++ Sbjct: 164 KEGVREVFEMATRAGLQVRKN 184 >gi|7656900 ras homolog D [Homo sapiens] Length = 210 Score = 108 bits (270), Expect = 2e-23 Identities = 72/212 (33%), Positives = 108/212 (50%), Gaps = 27/212 (12%) Query: 10 PNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERS 69 P V ++K V+VGD GKT L+ A Y PTV+ ++Y V +V + Sbjct: 13 PGVRSVKVVLVGDGGCGKTSLLMVFADGAFPESY------TPTVF--ERYMVNLQVKGKP 64 Query: 70 RDVVDEVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIK 127 V L +WDT G D+ + R Y + V++LCF + +PNS +++ + WYPE+ Sbjct: 65 --------VHLHIWDTAGQDDYDRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPEVN 116 Query: 128 HFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELG-LPYY 186 HFC + P+I+VGC+ DLR D VN+ RR P+ +G+E+A+ +G + Y Sbjct: 117 HFCKKVPIIVVGCKTDLR-KDKSLVNKLRRNGLEPVTY------HRGQEMARSVGAVAYL 169 Query: 187 ETSVFDQFGIKDVFDNAIRAALISRRHLQFWK 218 E S + VF A AL SR FW+ Sbjct: 170 ECSARLHDNVHAVFQEAAEVALSSRGR-NFWR 200 >gi|4757764 ras homolog gene family, member B [Homo sapiens] Length = 196 Score = 103 bits (258), Expect = 4e-22 Identities = 71/199 (35%), Positives = 103/199 (51%), Gaps = 26/199 (13%) Query: 16 KCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDE 75 K VVVGD A GKT L+ ++ + +VPTV+ + Y EV D Sbjct: 7 KLVVVGDGACGKTCLLIV------FSKDEFPEVYVPTVF--ENYVADIEV--------DG 50 Query: 76 VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHFCPRT 133 V L LWDT G D+ + R +Y +DV+++CFS+ +P+SL ++ W PE+KHFCP Sbjct: 51 KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNV 110 Query: 134 PVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKEL-GLPYYETSVFD 192 P+ILV + DLR +D R P++ D GR +A + Y E S Sbjct: 111 PIILVANKKDLR-SDEHVRTELARMKQEPVRTDD------GRAMAVRIQAYDYLECSAKT 163 Query: 193 QFGIKDVFDNAIRAALISR 211 + G+++VF+ A RAAL R Sbjct: 164 KEGVREVFETATRAALQKR 182 >gi|11034843 ras homolog gene family, member U [Homo sapiens] Length = 258 Score = 102 bits (255), Expect = 9e-22 Identities = 70/197 (35%), Positives = 100/197 (50%), Gaps = 26/197 (13%) Query: 15 IKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 74 +KCV+VGD AVGKT L+ + N T+Y +PT A D + V D Sbjct: 50 VKCVLVGDGAVGKTSLVVSYTTNGYPTEY------IPT--AFDNFSAVVSV--------D 93 Query: 75 EVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHFCPR 132 V L+L DT G D R Y +D+ +LCFS+ +P+S +V W PEI+ CP+ Sbjct: 94 GRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPK 153 Query: 133 TPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKEL-GLPYYETSVF 191 P+ILVG Q DLR D++ + + +P+ P E + A+E+ Y E S Sbjct: 154 APIILVGTQSDLR-EDVKVLIELDKCKEKPV------PEEAAKLCAEEIKAASYIECSAL 206 Query: 192 DQFGIKDVFDNAIRAAL 208 Q +K+VFD AI A + Sbjct: 207 TQKNLKEVFDAAIVAGI 223 >gi|229577148 ras homolog gene family, member V [Homo sapiens] Length = 236 Score = 101 bits (252), Expect = 2e-21 Identities = 71/203 (34%), Positives = 102/203 (50%), Gaps = 23/203 (11%) Query: 15 IKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 74 IKCV+VGD AVGK+ LI + CN +Y+ PT A+D + V + +VD Sbjct: 32 IKCVLVGDGAVGKSSLIVSYTCNGYPARYR------PT--ALDTFSV--------QVLVD 75 Query: 75 EVSVSLRLWDTFGDHHKDR--RFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHFCPR 132 V + LWDT G DR Y +DV + CFS+ P+S ++ W PEI+ P+ Sbjct: 76 GAPVRIELWDTAGQEDFDRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQ 135 Query: 133 TPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGLPYYETSVFD 192 PV+LVG Q DLR + VN L + + G + P+ K Y E S Sbjct: 136 APVLLVGTQADLR----DDVN-VLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALT 190 Query: 193 QFGIKDVFDNAIRAALISRRHLQ 215 Q +K+VFD+AI +A+ + L+ Sbjct: 191 QKNLKEVFDSAILSAIEHKARLE 213 >gi|16903164 ras homolog gene family, member J [Homo sapiens] Length = 214 Score = 98.2 bits (243), Expect = 2e-20 Identities = 72/193 (37%), Positives = 102/193 (52%), Gaps = 26/193 (13%) Query: 15 IKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVD 74 +KCVVVGD AVGKT L+ + A + +Y VPTV+ D Y V V + Sbjct: 22 LKCVVVGDGAVGKTCLLMSYANDAFPEEY------VPTVF--DHYAVTVTVGGKQH---- 69 Query: 75 EVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHFCPR 132 L L+DT G D+++ R +Y +DV ++CFS+ NP S ++V+ W PE+K P Sbjct: 70 ----LLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPH 125 Query: 133 TPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGLP-YYETSVF 191 P +L+G Q+DLR D + + R +P L E G ++AK +G Y E S Sbjct: 126 VPYVLIGTQIDLR-DDPKTLARLLYMKEKP------LTYEHGVKLAKAIGAQCYLECSAL 178 Query: 192 DQFGIKDVFDNAI 204 Q G+K VFD AI Sbjct: 179 TQKGLKAVFDEAI 191 >gi|7657514 GTP-binding protein RHO6 [Homo sapiens] Length = 232 Score = 93.2 bits (230), Expect = 7e-19 Identities = 77/230 (33%), Positives = 105/230 (45%), Gaps = 32/230 (13%) Query: 9 RPNVETIKCVVVGDNAVGKTRL--ICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVL 66 +P V K V+VGD GKT + + A+ C T+VPTV+ + Y C E Sbjct: 8 QPVVARCKLVLVGDVQCGKTAMLQVLAKDCYPE--------TYVPTVF--ENYTACLET- 56 Query: 67 ERSRDVVDEVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLNHVKSMWYP 124 +E V L LWDT G + D R Y SD V+LCF I+ P +++ W Sbjct: 57 -------EEQRVELSLWDTSGSPYYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRT 109 Query: 125 EIKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGLP 184 EI +CP T V+L+GC+ DLR DL + PI E+G +AK+LG Sbjct: 110 EILDYCPSTRVLLIGCKTDLR-TDLSTLMELSHQKQAPISY------EQGCAIAKQLGAE 162 Query: 185 -YYETSVF-DQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAP 232 Y E S F + I +F A L L KS ++ + K LL P Sbjct: 163 IYLEGSAFTSEKSIHSIFRTASMLCLNKPSPLP-QKSPVRSLSKRLLHLP 211 >gi|4885581 Rho family GTPase 2 [Homo sapiens] Length = 227 Score = 90.5 bits (223), Expect = 5e-18 Identities = 69/212 (32%), Positives = 103/212 (48%), Gaps = 28/212 (13%) Query: 16 KCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDE 75 K VVVGD GKT L+ A + Y VPTV+ + Y E+ D+ Sbjct: 9 KIVVVGDAECGKTALLQVFAKDAYPGSY------VPTVF--ENYTASFEI--------DK 52 Query: 76 VSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHFCPRT 133 + L +WDT G + D R AY SD V++CF I+ P +L+ V W E + FCP Sbjct: 53 RRIELNMWDTSGSSYYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNA 112 Query: 134 PVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGLPYYE--TSVF 191 V+LVGC+LD+R DL + + P+ E+G +AK++G Y +S Sbjct: 113 KVVLVGCKLDMR-TDLATLRELSKQRLIPVTH------EQGTVLAKQVGAVSYVECSSRS 165 Query: 192 DQFGIKDVFDNAIRAALISRRHLQFWKSHLKK 223 + ++DVF A A+L R H Q ++ ++ Sbjct: 166 SERSVRDVFHVATVASL-GRGHRQLRRTDSRR 196 >gi|4757770 ras homolog gene family, member H [Homo sapiens] Length = 191 Score = 87.8 bits (216), Expect = 3e-17 Identities = 64/204 (31%), Positives = 101/204 (49%), Gaps = 33/204 (16%) Query: 12 VETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRD 71 + +IKCV+VGD+AVGKT L+ T Y+ PTV+ V Sbjct: 2 LSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYK------PTVYENTGVDV---------- 45 Query: 72 VVDEVSVSLRLWDTFGDH--HKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHF 129 +D + +SL LWDT G+ R +Y ++DVV++C+S+AN NS ++K+ W EI+ Sbjct: 46 FMDGIQISLGLWDTAGNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSN 105 Query: 130 CPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKEL-GLPYYET 188 P TPV++V Q D R P R + +G+++A+++ Y E Sbjct: 106 LPCTPVLVVATQTD---------QREMGP-----HRASCVNAMEGKKLAQDVRAKGYLEC 151 Query: 189 SVFDQFGIKDVFDNAIRAALISRR 212 S G++ VF+ A+R A+ R Sbjct: 152 SALSNRGVQQVFECAVRTAVNQAR 175 >gi|4885069 ras homolog gene family, member E [Homo sapiens] Length = 244 Score = 87.0 bits (214), Expect = 5e-17 Identities = 69/232 (29%), Positives = 111/232 (47%), Gaps = 31/232 (13%) Query: 10 PNVETIKC--VVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLE 67 PN + +KC VVVGD+ GKT L+ A + Y VPTV+ + Y E+ Sbjct: 18 PN-QNVKCKIVVVGDSQCGKTALLHVFAKDCFPENY------VPTVF--ENYTASFEI-- 66 Query: 68 RSRDVVDEVSVSLRLWDTFGDHHKD--RRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPE 125 D + L LWDT G + D R +Y SD V++CF I+ P +L+ V W E Sbjct: 67 ------DTQRIELSLWDTSGSPYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGE 120 Query: 126 IKHFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELG-LP 184 I+ FCP T ++LVGC+ DLR D+ + P+ ++G +AK++G Sbjct: 121 IQEFCPNTKMLLVGCKSDLR-TDVSTLVELSNHRQTPVSY------DQGANMAKQIGAAT 173 Query: 185 YYETSVF-DQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLP 235 Y E S + ++D+F + A +++ + ++ ++ K + P P Sbjct: 174 YIECSALQSENSVRDIF-HVATLACVNKTNKNVKRNKSQRATKRISHMPSRP 224 >gi|38016957 ras homolog gene family, member F [Homo sapiens] Length = 211 Score = 83.2 bits (204), Expect = 8e-16 Identities = 59/209 (28%), Positives = 101/209 (48%), Gaps = 26/209 (12%) Query: 10 PNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERS 69 P + +K V+VGD GKT L+ + + Y P+V+ ++Y V + Sbjct: 15 PGRKELKIVIVGDGGCGKTSLLMVYSQGSFPEHY------APSVF--EKYTASVTVGSKE 66 Query: 70 RDVVDEVSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIK 127 V+L L+DT G D+ + R +Y + +V++C+ + NP S ++V W+PE+ Sbjct: 67 --------VTLNLYDTAGQEDYDRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVT 118 Query: 128 HFCPRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKEL-GLPYY 186 HFC P++L+GC+ DLR D E + + R PI +G +++ Y Sbjct: 119 HFCRGIPMVLIGCKTDLR-KDKEQLRKLRAAQLEPITY------MQGLSACEQIRAALYL 171 Query: 187 ETSVFDQFGIKDVFDNAIRAALISRRHLQ 215 E S + ++DVF A + AL + + Q Sbjct: 172 ECSAKFRENVEDVFREAAKVALSALKKAQ 200 >gi|7549817 RAB, member of RAS oncogene family-like 2A [Homo sapiens] Length = 228 Score = 56.2 bits (134), Expect = 1e-07 Identities = 49/205 (23%), Positives = 88/205 (42%), Gaps = 41/205 (20%) Query: 13 ETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDV 72 + +K + +GD+AVGK++L+ + Q Q L+T+ T++ + Sbjct: 20 DNVKIICLGDSAVGKSKLMERFLMDGF--QPQQLSTYALTLY-------------KHTAT 64 Query: 73 VDEVSVSLRLWDTFGDHHKDRRFA--YGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHFC 130 VD ++ + WDT G A Y ++ ++ F I + ++ S WY E++ F Sbjct: 65 VDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDIQRKVTYRNL-STWYTELREFR 123 Query: 131 PRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGLPYYETSV 190 P P I+V ++D DI +K AK+ LP Y S Sbjct: 124 PEIPCIVVANKID-----------------------DINVTQKSFNFAKKFSLPLYFVSA 160 Query: 191 FDQFGIKDVFDNAIRAALISRRHLQ 215 D + +F++AIR A+ +++ Q Sbjct: 161 ADGTNVVKLFNDAIRLAVSYKQNSQ 185 >gi|5902038 RAB, member of RAS oncogene family-like 2A [Homo sapiens] Length = 228 Score = 56.2 bits (134), Expect = 1e-07 Identities = 49/205 (23%), Positives = 88/205 (42%), Gaps = 41/205 (20%) Query: 13 ETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDV 72 + +K + +GD+AVGK++L+ + Q Q L+T+ T++ + Sbjct: 20 DNVKIICLGDSAVGKSKLMERFLMDGF--QPQQLSTYALTLY-------------KHTAT 64 Query: 73 VDEVSVSLRLWDTFGDHHKDRRFA--YGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHFC 130 VD ++ + WDT G A Y ++ ++ F I + ++ S WY E++ F Sbjct: 65 VDGKTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDIQRKVTYRNL-STWYTELREFR 123 Query: 131 PRTPVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELGLPYYETSV 190 P P I+V ++D DI +K AK+ LP Y S Sbjct: 124 PEIPCIVVANKID-----------------------DINVTQKSFNFAKKFSLPLYFVSA 160 Query: 191 FDQFGIKDVFDNAIRAALISRRHLQ 215 D + +F++AIR A+ +++ Q Sbjct: 161 ADGTNVVKLFNDAIRLAVSYKQNSQ 185 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.135 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,818,684 Number of Sequences: 37866 Number of extensions: 1266365 Number of successful extensions: 4949 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 109 Number of HSP's successfully gapped in prelim test: 143 Number of HSP's that attempted gapping in prelim test: 4612 Number of HSP's gapped (non-prelim): 366 length of query: 696 length of database: 18,247,518 effective HSP length: 109 effective length of query: 587 effective length of database: 14,120,124 effective search space: 8288512788 effective search space used: 8288512788 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.