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Search of human proteins with 28373124
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28373124 contactin 4 isoform b precursor [Homo sapiens]
(282 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28373126 contactin 4 isoform c precursor [Homo sapiens] 563 e-161
gi|28373124 contactin 4 isoform b precursor [Homo sapiens] 563 e-161
gi|28373122 contactin 4 isoform a precursor [Homo sapiens] 563 e-161
gi|75709184 contactin 3 [Homo sapiens] 339 2e-93
gi|7657361 contactin 6 [Homo sapiens] 300 7e-82
gi|7657359 contactin 5 isoform long [Homo sapiens] 249 2e-66
gi|28373129 contactin 5 isoform short [Homo sapiens] 249 2e-66
gi|4827022 contactin 2 precursor [Homo sapiens] 212 3e-55
gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens] 198 4e-51
gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens] 198 4e-51
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa... 100 1e-21
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 95 6e-20
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 94 1e-19
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 94 1e-19
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 94 1e-19
gi|104487002 protein tyrosine phosphatase, receptor type, D isof... 93 2e-19
gi|18860894 protein tyrosine phosphatase, receptor type, D isofo... 93 2e-19
gi|222352127 sidekick 2 [Homo sapiens] 92 4e-19
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 86 4e-17
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 86 4e-17
gi|104487611 protein tyrosine phosphatase, receptor type, sigma ... 85 8e-17
gi|104487297 protein tyrosine phosphatase, receptor type, sigma ... 85 8e-17
gi|104487295 protein tyrosine phosphatase, receptor type, sigma ... 85 8e-17
gi|104487006 protein tyrosine phosphatase, receptor type, sigma ... 85 8e-17
gi|119220552 sidekick 1 [Homo sapiens] 84 1e-16
gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo... 82 7e-16
gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo ... 82 7e-16
gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo s... 82 7e-16
gi|27894376 cell adhesion molecule with homology to L1CAM precur... 81 1e-15
gi|81158224 neuronal cell adhesion molecule isoform B precursor ... 75 6e-14
>gi|28373126 contactin 4 isoform c precursor [Homo sapiens]
Length = 698
Score = 563 bits (1452), Expect = e-161
Identities = 282/282 (100%), Positives = 282/282 (100%)
Query: 1 MIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKP 60
MIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKP
Sbjct: 417 MIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKP 476
Query: 61 PASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKI 120
PASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKI
Sbjct: 477 PASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKI 536
Query: 121 TNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQV 180
TNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQV
Sbjct: 537 TNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQV 596
Query: 181 KALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSS 240
KALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSS
Sbjct: 597 KALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSS 656
Query: 241 EQIRIPKISNAYARGSGASTSNACTLSAISTIMISLTARSSL 282
EQIRIPKISNAYARGSGASTSNACTLSAISTIMISLTARSSL
Sbjct: 657 EQIRIPKISNAYARGSGASTSNACTLSAISTIMISLTARSSL 698
>gi|28373124 contactin 4 isoform b precursor [Homo sapiens]
Length = 282
Score = 563 bits (1452), Expect = e-161
Identities = 282/282 (100%), Positives = 282/282 (100%)
Query: 1 MIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKP 60
MIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKP
Sbjct: 1 MIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKP 60
Query: 61 PASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKI 120
PASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKI
Sbjct: 61 PASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKI 120
Query: 121 TNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQV 180
TNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQV
Sbjct: 121 TNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQV 180
Query: 181 KALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSS 240
KALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSS
Sbjct: 181 KALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSS 240
Query: 241 EQIRIPKISNAYARGSGASTSNACTLSAISTIMISLTARSSL 282
EQIRIPKISNAYARGSGASTSNACTLSAISTIMISLTARSSL
Sbjct: 241 EQIRIPKISNAYARGSGASTSNACTLSAISTIMISLTARSSL 282
>gi|28373122 contactin 4 isoform a precursor [Homo sapiens]
Length = 1026
Score = 563 bits (1452), Expect = e-161
Identities = 282/282 (100%), Positives = 282/282 (100%)
Query: 1 MIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKP 60
MIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKP
Sbjct: 745 MIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKP 804
Query: 61 PASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKI 120
PASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKI
Sbjct: 805 PASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKI 864
Query: 121 TNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQV 180
TNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQV
Sbjct: 865 TNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQV 924
Query: 181 KALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSS 240
KALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSS
Sbjct: 925 KALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSS 984
Query: 241 EQIRIPKISNAYARGSGASTSNACTLSAISTIMISLTARSSL 282
EQIRIPKISNAYARGSGASTSNACTLSAISTIMISLTARSSL
Sbjct: 985 EQIRIPKISNAYARGSGASTSNACTLSAISTIMISLTARSSL 1026
>gi|75709184 contactin 3 [Homo sapiens]
Length = 1028
Score = 339 bits (869), Expect = 2e-93
Identities = 159/275 (57%), Positives = 214/275 (77%), Gaps = 1/275 (0%)
Query: 3 WMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPA 62
W+ TV+ S D RYVFRNES+ P+SP+EVKVGV+NNKGEGPFSP T V+SAEEEPT P+
Sbjct: 748 WIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPS 807
Query: 63 SIFARSLSATDIEVFWAS-PLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKIT 121
+ A SLS+++IEV W + P + + G + GYEV+YW KEE++ K++ GN+TS ++
Sbjct: 808 QVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGNETSARLR 867
Query: 122 NLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVK 181
LK ++ Y+ AV+AYNSAG GP SATVNVTT+K PPSQPPGN++WN++D+K++LNW+QVK
Sbjct: 868 GLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVK 927
Query: 182 ALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSE 241
A++NESEV GYKV YR + Q++ V+ TNKTS EL LP EDYIIE+K +DGGDG+SSE
Sbjct: 928 AMENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELVLPIKEDYIIEVKATTDGGDGTSSE 987
Query: 242 QIRIPKISNAYARGSGASTSNACTLSAISTIMISL 276
QIRIP+I++ ARGS ++ SN +S+ I++ L
Sbjct: 988 QIRIPRITSMDARGSTSAISNVHPMSSYMPIVLFL 1022
Score = 60.5 bits (145), Expect = 2e-09
Identities = 63/261 (24%), Positives = 104/261 (39%), Gaps = 33/261 (12%)
Query: 6 TVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEG-PFSPTTVVYSAEEEPTKPPASI 64
TV D + ++P+ +E +V N G G P P+ V + E P PP+ +
Sbjct: 648 TVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEV 707
Query: 65 FARSLSATDIEVFW-ASPLEKNRGRIQGYEVKY-------WRHEDKEENARKIRTVGNQT 116
S +++ + W P E G GY V + W I+TV
Sbjct: 708 NGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGVTTW-----------IQTVVTSP 756
Query: 117 STKITNLKGSVL-----YHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNS-SD 170
T + + Y + V YN+ G GP S V + + P+ P + NS S
Sbjct: 757 DTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSS 816
Query: 171 SKIILNWDQVKALDNESEVKGYKVLYRWN-----RQSSTSVIETNKTSVEL-SLPFDEDY 224
S+I ++W+ + + + GY+V Y WN SS + N+TS L L + Y
Sbjct: 817 SEIEVSWNTIPWKLSNGHLLGYEVRY-WNGGGKEESSSKMKVAGNETSARLRGLKSNLAY 875
Query: 225 IIEIKPFSDGGDGSSSEQIRI 245
++ ++ G G S + +
Sbjct: 876 YTAVRAYNSAGAGPFSATVNV 896
Score = 37.4 bits (85), Expect = 0.015
Identities = 46/188 (24%), Positives = 72/188 (38%), Gaps = 29/188 (15%)
Query: 60 PPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTK 119
PP ++ ++ T ++ W + N + Y ++ AR +VG QT T
Sbjct: 600 PPENVKVDEITDTTAQLSWKEGKD-NHSPVISYSIQ----------ARTPFSVGWQTVTT 648
Query: 120 I-------------TNLKGSVLYHLAVKAYNSAGTG-PSSATVNVTTRKPPPSQPPGNII 165
+ L V Y V A N G G PS + V T + P PP +
Sbjct: 649 VPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVN 708
Query: 166 WNS-SDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVEL-SLPFDED 223
S S++++ WD V E GY V +R T+ I+T TS + F +
Sbjct: 709 GGGGSRSELVITWDPVPEELQNGEGFGYVVAFR--PLGVTTWIQTVVTSPDTPRYVFRNE 766
Query: 224 YIIEIKPF 231
I+ P+
Sbjct: 767 SIVPYSPY 774
>gi|7657361 contactin 6 [Homo sapiens]
Length = 1028
Score = 300 bits (769), Expect = 7e-82
Identities = 144/254 (56%), Positives = 186/254 (73%), Gaps = 1/254 (0%)
Query: 3 WMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPA 62
W ++S ++SR+V+RNES+ P SPFEVKVGV+NN+GEG S T+VYS E+EP P
Sbjct: 748 WSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPR 807
Query: 63 SIFARSLSATDIEVFW-ASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKIT 121
+S SA+++EV W A +N GR+ GYEV YW + KE KIR GN T+ IT
Sbjct: 808 GTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTTKNIT 867
Query: 122 NLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVK 181
LK + +Y +V+AYN+AGTGPSS VNVTT+K PPSQPP NI W ++SK+ LNW+ VK
Sbjct: 868 GLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEHVK 927
Query: 182 ALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSE 241
++NESEV GYK+LYR NRQS T ++ETN TS EL +PF+EDY+IEI+ SDGGDGSSSE
Sbjct: 928 TMENESEVLGYKILYRQNRQSKTHILETNNTSAELLVPFEEDYLIEIRTVSDGGDGSSSE 987
Query: 242 QIRIPKISNAYARG 255
+IRIPK+S+ +RG
Sbjct: 988 EIRIPKMSSLSSRG 1001
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 249 bits (636), Expect = 2e-66
Identities = 125/275 (45%), Positives = 180/275 (65%), Gaps = 7/275 (2%)
Query: 3 WMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPA 62
W ++ S++AS++++R+ESV P +PFEVKVGV+NNKG+GPFS V+ SAE EP+ P
Sbjct: 821 WKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPT 880
Query: 63 SIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITN 122
+ A S+S ++I V W ++++ GR QG+EV YW+ ++E+ A ++T GN++ +T
Sbjct: 881 DVKATSVSVSEILVAWKH-IKESLGRPQGFEVGYWKDMEQEDTAETVKTRGNESFVILTG 939
Query: 123 LKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKA 182
L+G+ LYH V+AYN AG GP S+ V+ TT+K PPSQ P N+ W S++ L W+ V
Sbjct: 940 LEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSNLRWEQQGSQVSLGWEPVIP 999
Query: 183 LDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQ 242
L NESEV GYKV YR S++ VIET K + LP YIIE++ +S+GGDG++S Q
Sbjct: 1000 LANESEVVGYKVFYRQEGHSNSQVIETQKLQAVVPLPDAGVYIIEVRAYSEGGDGTASSQ 1059
Query: 243 IRIPKISNAYARGSGASTSNACTLSAISTIMISLT 277
IR+P S G TS TL ++ST S+T
Sbjct: 1060 IRVPSYS------GGKITSAQSTLHSLSTSSSSVT 1088
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 249 bits (636), Expect = 2e-66
Identities = 125/275 (45%), Positives = 180/275 (65%), Gaps = 7/275 (2%)
Query: 3 WMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPA 62
W ++ S++AS++++R+ESV P +PFEVKVGV+NNKG+GPFS V+ SAE EP+ P
Sbjct: 747 WKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPT 806
Query: 63 SIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITN 122
+ A S+S ++I V W ++++ GR QG+EV YW+ ++E+ A ++T GN++ +T
Sbjct: 807 DVKATSVSVSEILVAWKH-IKESLGRPQGFEVGYWKDMEQEDTAETVKTRGNESFVILTG 865
Query: 123 LKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKA 182
L+G+ LYH V+AYN AG GP S+ V+ TT+K PPSQ P N+ W S++ L W+ V
Sbjct: 866 LEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSNLRWEQQGSQVSLGWEPVIP 925
Query: 183 LDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQ 242
L NESEV GYKV YR S++ VIET K + LP YIIE++ +S+GGDG++S Q
Sbjct: 926 LANESEVVGYKVFYRQEGHSNSQVIETQKLQAVVPLPDAGVYIIEVRAYSEGGDGTASSQ 985
Query: 243 IRIPKISNAYARGSGASTSNACTLSAISTIMISLT 277
IR+P S G TS TL ++ST S+T
Sbjct: 986 IRVPSYS------GGKITSAQSTLHSLSTSSSSVT 1014
>gi|4827022 contactin 2 precursor [Homo sapiens]
Length = 1040
Score = 212 bits (540), Expect = 3e-55
Identities = 100/240 (41%), Positives = 151/240 (62%), Gaps = 1/240 (0%)
Query: 3 WMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPA 62
W + ADA +V+ NESV P++PFEVK+ +N +G+GP S T +VYSAEEEP P
Sbjct: 758 WQTARVPGADAQYFVYSNESVRPYTPFEVKIRSYNRRGDGPESLTALVYSAEEEPRVAPT 817
Query: 63 SIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITN 122
++A+ +S++++ V W + G + GYE++YW+ DKE A ++RT G TS +++
Sbjct: 818 KVWAKGVSSSEMNVTWEPVQQDMNGILLGYEIRYWKAGDKEAAADRVRTAGLDTSARVSG 877
Query: 123 LKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKA 182
L + YH+ V+AYN AGTGP+S + N TT KPPP +PPGNI W S S + + WD V
Sbjct: 878 LHPNTKYHVTVRAYNRAGTGPASPSANATTMKPPPRRPPGNISWTFSSSSLSIKWDPVVP 937
Query: 183 LDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDY-IIEIKPFSDGGDGSSSE 241
NES V GYK+LY+ + + ++ T K +E+ +P D + +++I+ GGDG +E
Sbjct: 938 FRNESAVTGYKMLYQNDLHLTPTLHLTGKNWIEIPVPEDIGHALVQIRTTGPGGDGIPAE 997
Score = 51.6 bits (122), Expect = 8e-07
Identities = 60/251 (23%), Positives = 100/251 (39%), Gaps = 47/251 (18%)
Query: 48 TVVYSAEEE-------PTKPPASIFARSLSATDIEVFWA------SPLEKNRGRIQGYEV 94
TVV SA +E P PP + R + T I++ W+ SP+ K + +
Sbjct: 591 TVVDSASKEATVLVRGPPGPPGGVVVRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTPPA 650
Query: 95 KYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTG-PSSATVNVTTR 153
W K+ GN + ++ L + Y V A N GTG PS + + TR
Sbjct: 651 GKW----KQVRTNPANIEGNAETAQVLGLTPWMDYEFRVIASNILGTGEPSGPSSKIRTR 706
Query: 154 KPPPSQPPGNII-WNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSST-------- 204
+ PS P + + ++I+NW + + GY + +R RQ ST
Sbjct: 707 EAAPSVAPSGLSGGGGAPGELIVNWTPMSREYQNGDGFGYLLSFR--RQGSTHWQTARVP 764
Query: 205 ----SVIETNKTSVELSLPFDEDYIIEIKPFSDGGDG---------SSSEQIRIPKISNA 251
+ SV PF+ ++I+ ++ GDG S+ E+ R+ +
Sbjct: 765 GADAQYFVYSNESVRPYTPFE----VKIRSYNRRGDGPESLTALVYSAEEEPRVAP-TKV 819
Query: 252 YARGSGASTSN 262
+A+G +S N
Sbjct: 820 WAKGVSSSEMN 830
Score = 32.0 bits (71), Expect = 0.63
Identities = 27/105 (25%), Positives = 43/105 (40%), Gaps = 8/105 (7%)
Query: 111 TVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSD 170
T+G+ T G +A +SA ATV V + PP P G ++ + D
Sbjct: 568 TIGDLTILNAQLRHGGKYTCMAQTVVDSAS---KEATVLV---RGPPGPPGGVVVRDIGD 621
Query: 171 SKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVE 215
+ I L+W + DN S + Y + R + TN ++E
Sbjct: 622 TTIQLSWS--RGFDNHSPIAKYTLQARTPPAGKWKQVRTNPANIE 664
>gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens]
Length = 1018
Score = 198 bits (504), Expect = 4e-51
Identities = 97/239 (40%), Positives = 145/239 (60%), Gaps = 3/239 (1%)
Query: 3 WMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPA 62
W + + D RYV ++E++ P + F+VKV FNNKG+GP+S V+ SA++ P++ P
Sbjct: 754 WKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPT 813
Query: 63 SIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITN 122
+ + LS+++I V W LEK ++ Y+++YW DKEE A +++ + S ++ N
Sbjct: 814 EVGVKVLSSSEISVHWEHVLEKI---VESYQIRYWAAHDKEEAANRVQVTSQEYSARLEN 870
Query: 123 LKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKA 182
L Y + V A NSAG GP S + T+K PPSQPP I S S+ I+ WD V A
Sbjct: 871 LLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVA 930
Query: 183 LDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSE 241
L NES V GYKVLYR + Q + T+K S+E+ +P D +Y++E++ SDGGDG S+
Sbjct: 931 LSNESTVTGYKVLYRPDGQHDGKLYSTHKHSIEVPIPRDGEYVVEVRAHSDGGDGVVSQ 989
>gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens]
Length = 1007
Score = 198 bits (504), Expect = 4e-51
Identities = 97/239 (40%), Positives = 145/239 (60%), Gaps = 3/239 (1%)
Query: 3 WMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPA 62
W + + D RYV ++E++ P + F+VKV FNNKG+GP+S V+ SA++ P++ P
Sbjct: 743 WKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPT 802
Query: 63 SIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITN 122
+ + LS+++I V W LEK ++ Y+++YW DKEE A +++ + S ++ N
Sbjct: 803 EVGVKVLSSSEISVHWEHVLEKI---VESYQIRYWAAHDKEEAANRVQVTSQEYSARLEN 859
Query: 123 LKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKA 182
L Y + V A NSAG GP S + T+K PPSQPP I S S+ I+ WD V A
Sbjct: 860 LLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVA 919
Query: 183 LDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSE 241
L NES V GYKVLYR + Q + T+K S+E+ +P D +Y++E++ SDGGDG S+
Sbjct: 920 LSNESTVTGYKVLYRPDGQHDGKLYSTHKHSIEVPIPRDGEYVVEVRAHSDGGDGVVSQ 978
>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
sapiens]
Length = 2113
Score = 100 bits (250), Expect = 1e-21
Identities = 66/237 (27%), Positives = 115/237 (48%), Gaps = 18/237 (7%)
Query: 23 VHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPL 82
+HP S + +++ FN G S + + E P PP + + +++ I+V W +P
Sbjct: 1012 LHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPK 1071
Query: 83 -EKNRGRIQGYEVKYWRHEDKEENAR----KIRTVGNQTSTKITNLKGSVLYHLAVKAYN 137
E G I+GY++ Y R N + +++ G+ + NLK Y + V+A+N
Sbjct: 1072 KELQNGVIRGYQIGY-RENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFN 1130
Query: 138 SAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKI-ILNWDQVKALDNESEVKGYKVLY 196
AGTGPSS+ +N TT + PSQPP N+ S S + +++W + +KGY+V++
Sbjct: 1131 RAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIF 1190
Query: 197 -------RWNRQSSTSVIETNKTSVEL-SLPFDEDYIIEIKPFSDGGDGSSSEQIRI 245
W + I T + VEL + +Y +++ ++ GDG S + I
Sbjct: 1191 WSLYVDGEWGEMQN---ITTTRERVELRGMEKFTNYSVQVLAYTQAGDGVRSSVLYI 1244
Score = 73.9 bits (180), Expect = 1e-13
Identities = 57/252 (22%), Positives = 109/252 (43%), Gaps = 10/252 (3%)
Query: 9 ASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARS 68
A+ D+ Y N + F+ + V V FN G GP S + E+ P++PP ++ A S
Sbjct: 1104 ATGDSEVYTLDN--LKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALS 1161
Query: 69 LSATDIEVFWASPLEKN-RGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSV 127
+++ + W+ P G ++GY V +W E + ++ ++
Sbjct: 1162 ITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRERVELRGMEKFT 1221
Query: 128 LYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNES 187
Y + V AY AG G S+ + + T++ P P G SS S ++++W +
Sbjct: 1222 NYSVQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVVSW--LPPTKPNG 1279
Query: 188 EVKGYKVLYR--WNRQSSTSVIETNKTSVELSLPF---DEDYIIEIKPFSDGGDGSSSEQ 242
++ Y + + Q + S ET+ + + + Y++ + + G G+SSE+
Sbjct: 1280 VIRKYTIFCSSPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEK 1339
Query: 243 IRIPKISNAYAR 254
+ I A A+
Sbjct: 1340 VTIEPAGKAPAK 1351
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 95.1 bits (235), Expect = 6e-20
Identities = 66/231 (28%), Positives = 107/231 (46%), Gaps = 10/231 (4%)
Query: 23 VHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPL 82
+HP S + +++ N G+ S + + E P PP + +S+ I V W +P
Sbjct: 950 IHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAPK 1009
Query: 83 EK-NRGRIQGYEVKYWRHE---DKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNS 138
+ G I+GY++ Y + + + N + T G+ + NL Y L V+A N
Sbjct: 1010 KHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNR 1069
Query: 139 AGTGPSSATVNVTTRKPPPSQPPGNI-IWNSSDSKIILNWDQVKALDNESEVKGYKVLYR 197
AGTGPSS + TT + PS PP N+ +S I ++W + ++G++V+Y
Sbjct: 1070 AGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYW 1129
Query: 198 WNRQSSTSVIETNKTSVELSLPFD-----EDYIIEIKPFSDGGDGSSSEQI 243
N N T+ + SL D +Y I++ F+ GDG SEQI
Sbjct: 1130 ANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQI 1180
Score = 77.4 bits (189), Expect = 1e-14
Identities = 62/255 (24%), Positives = 110/255 (43%), Gaps = 8/255 (3%)
Query: 4 MLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPAS 63
+++V S D+ Y N ++ F+ + + V N G GP S + + E+ P+ PP +
Sbjct: 1037 IISVDTSGDSEVYTLDN--LNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPEN 1094
Query: 64 IFARSLSATDIEVFWAS-PLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITN 122
+ A + S I + W++ E G +QG+ V YW + E Q S ++
Sbjct: 1095 VQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLMDGELGEIKNITTTQPSLELDG 1154
Query: 123 LKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKA 182
L+ Y + V A+ AG G S + T++ P P G +S S + ++W +
Sbjct: 1155 LEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSW--LPP 1212
Query: 183 LDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLP---FDEDYIIEIKPFSDGGDGSS 239
L ++ Y V + S E + S +P + Y + + + G G+S
Sbjct: 1213 LKLNGIIRKYTVFCSHPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNS 1272
Query: 240 SEQIRIPKISNAYAR 254
SE I + ++ A AR
Sbjct: 1273 SEIITVEPLAKAPAR 1287
Score = 32.3 bits (72), Expect = 0.48
Identities = 29/150 (19%), Positives = 55/150 (36%), Gaps = 3/150 (2%)
Query: 8 LASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFAR 67
L + D R +F N S + G ++ + ++ + + + +
Sbjct: 1329 LVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVPPDQPRLTVS 1388
Query: 68 SLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSV 127
+++ I + W P + I+GY ++Y ED E ++ S ++ NLK
Sbjct: 1389 KTTSSSITLSWL-PGDNGGSSIRGYILQY--SEDNSEQWGSFPISPSERSYRLENLKCGT 1445
Query: 128 LYHLAVKAYNSAGTGPSSATVNVTTRKPPP 157
Y + A N G G S + T P
Sbjct: 1446 WYKFTLTAQNGVGPGRISEIIEAKTLGKEP 1475
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 94.0 bits (232), Expect = 1e-19
Identities = 72/253 (28%), Positives = 114/253 (45%), Gaps = 10/253 (3%)
Query: 25 PFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEK 84
P+S +E +V NN G GP S + ++E+ P+ P + AR LS+T I V W P E
Sbjct: 385 PYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEP 444
Query: 85 NRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPS 144
N G+IQGY V Y + N V + T I NL Y + V A+ S G GP
Sbjct: 445 N-GQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPL 503
Query: 145 SATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSST 204
S+ + V T+ P QP S++ I+L+W ++ + Y+++Y+
Sbjct: 504 SSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRS----DTIANYELVYKDGEHGEE 559
Query: 205 SVIETNK-TSVEL-SLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGSGASTSN 262
I TS L L + Y + S G G+S+ +I ++ S
Sbjct: 560 QRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEI---SARTMQSKPSAPPQDI 616
Query: 263 ACTLSAISTIMIS 275
+CT + ++I++S
Sbjct: 617 SCTSPSSTSILVS 629
Score = 69.7 bits (169), Expect = 3e-12
Identities = 44/182 (24%), Positives = 86/182 (47%), Gaps = 3/182 (1%)
Query: 18 FRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVF 77
+R + + P S + ++ + +G G + + + +P+ PP I S S+T I V
Sbjct: 570 YRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVS 629
Query: 78 W-ASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTST-KITNLKGSVLYHLAVKA 135
W P+EK G I Y +KY + +++ +I + + T+ + L+ Y + V A
Sbjct: 630 WQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTA 689
Query: 136 YNSAGTGPSSATVNVTTRKPPPSQPPGNI-IWNSSDSKIILNWDQVKALDNESEVKGYKV 194
+ G GP S +V + T + PS PP + + + + + ++W +++GY+V
Sbjct: 690 HTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQV 749
Query: 195 LY 196
Y
Sbjct: 750 HY 751
Score = 66.2 bits (160), Expect = 3e-11
Identities = 47/199 (23%), Positives = 96/199 (48%), Gaps = 18/199 (9%)
Query: 11 ADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLS 70
+D ++Y+ E + ++ + + V + G GP S + ++ + E+ P+ PP + +++
Sbjct: 667 SDTTKYLL--EQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVN 724
Query: 71 ATDIEVFWASPL-EKNRGRIQGYEVKYWRHEDKEENAR-KIRTV-----------GNQTS 117
+T ++V W SP+ K G+I+GY+V Y R E+ E + ++ V +
Sbjct: 725 STSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHD 784
Query: 118 TKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNW 177
I+ L+ Y L V AY + G G S V+T P + P +I ++ + ++ W
Sbjct: 785 MIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGK-PRLVINHTQMNTALIQW 843
Query: 178 DQVKALDNESEVKGYKVLY 196
+D ++GY++ +
Sbjct: 844 H--PPVDTFGPLQGYRLKF 860
Score = 43.9 bits (102), Expect = 2e-04
Identities = 46/238 (19%), Positives = 88/238 (36%), Gaps = 11/238 (4%)
Query: 23 VHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPL 82
+ P + + + V + KG+G S +V + P KP I ++ I+ W P+
Sbjct: 790 LQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQ--WHPPV 847
Query: 83 EKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTG 142
+ G +QGY +K+ R + E + + T++ Y + A N G G
Sbjct: 848 D-TFGPLQGYRLKFGRKD--MEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFG 904
Query: 143 PSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNR-- 200
+ P P ++ + + L+W + + Y +LYR
Sbjct: 905 EEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIP 964
Query: 201 --QSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDG--SSSEQIRIPKISNAYAR 254
++ + T L D Y ++++ + G G S S Q R + +A+
Sbjct: 965 LLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAK 1022
Score = 37.4 bits (85), Expect = 0.015
Identities = 45/202 (22%), Positives = 82/202 (40%), Gaps = 29/202 (14%)
Query: 25 PFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFA-----RSLSATDIEVFWA 79
P + ++VKV +KG GP+SP+ + T P +FA +++ T + + W
Sbjct: 986 PDTTYDVKVRAHTSKGPGPYSPSV------QFRTLPVDQVFAKNFHVKAVMKTSVLLSWE 1039
Query: 80 SPLEKNRGRIQGYEVKYWRHEDKEENARKIRTV-GNQTSTKITNLKGSVLYHLAVKAYNS 138
P +N +++ Y ++ + + V G T I NLK Y + +
Sbjct: 1040 IP--ENYNSAMPFKILY-------DDGKMVEEVDGRATQKLIVNLKPEKSYSFVL---TN 1087
Query: 139 AGTGPSSATVNVTTRKPPP--SQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLY 196
G VT + P P I + D I + +V A +N +KGY ++
Sbjct: 1088 RGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANEN---IKGYYIII 1144
Query: 197 RWNRQSSTSVIETNKTSVELSL 218
++S I+ ++ E+ L
Sbjct: 1145 VPLKKSRGKFIKPWESPDEMEL 1166
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform
2 precursor [Homo sapiens]
Length = 1899
Score = 94.0 bits (232), Expect = 1e-19
Identities = 72/253 (28%), Positives = 114/253 (45%), Gaps = 10/253 (3%)
Query: 25 PFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEK 84
P+S +E +V NN G GP S + ++E+ P+ P + AR LS+T I V W P E
Sbjct: 372 PYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEP 431
Query: 85 NRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPS 144
N G+IQGY V Y + N V + T I NL Y + V A+ S G GP
Sbjct: 432 N-GQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPL 490
Query: 145 SATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSST 204
S+ + V T+ P QP S++ I+L+W ++ + Y+++Y+
Sbjct: 491 SSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRS----DTIANYELVYKDGEHGEE 546
Query: 205 SVIETNK-TSVEL-SLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGSGASTSN 262
I TS L L + Y + S G G+S+ +I ++ S
Sbjct: 547 QRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEI---SARTMQSKPSAPPQDI 603
Query: 263 ACTLSAISTIMIS 275
+CT + ++I++S
Sbjct: 604 SCTSPSSTSILVS 616
Score = 69.7 bits (169), Expect = 3e-12
Identities = 44/182 (24%), Positives = 86/182 (47%), Gaps = 3/182 (1%)
Query: 18 FRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVF 77
+R + + P S + ++ + +G G + + + +P+ PP I S S+T I V
Sbjct: 557 YRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVS 616
Query: 78 W-ASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTST-KITNLKGSVLYHLAVKA 135
W P+EK G I Y +KY + +++ +I + + T+ + L+ Y + V A
Sbjct: 617 WQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTA 676
Query: 136 YNSAGTGPSSATVNVTTRKPPPSQPPGNI-IWNSSDSKIILNWDQVKALDNESEVKGYKV 194
+ G GP S +V + T + PS PP + + + + + ++W +++GY+V
Sbjct: 677 HTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQV 736
Query: 195 LY 196
Y
Sbjct: 737 HY 738
Score = 66.2 bits (160), Expect = 3e-11
Identities = 47/199 (23%), Positives = 96/199 (48%), Gaps = 18/199 (9%)
Query: 11 ADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLS 70
+D ++Y+ E + ++ + + V + G GP S + ++ + E+ P+ PP + +++
Sbjct: 654 SDTTKYLL--EQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVN 711
Query: 71 ATDIEVFWASPL-EKNRGRIQGYEVKYWRHEDKEENAR-KIRTV-----------GNQTS 117
+T ++V W SP+ K G+I+GY+V Y R E+ E + ++ V +
Sbjct: 712 STSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHD 771
Query: 118 TKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNW 177
I+ L+ Y L V AY + G G S V+T P + P +I ++ + ++ W
Sbjct: 772 MIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGK-PRLVINHTQMNTALIQW 830
Query: 178 DQVKALDNESEVKGYKVLY 196
+D ++GY++ +
Sbjct: 831 H--PPVDTFGPLQGYRLKF 847
Score = 43.9 bits (102), Expect = 2e-04
Identities = 46/238 (19%), Positives = 88/238 (36%), Gaps = 11/238 (4%)
Query: 23 VHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPL 82
+ P + + + V + KG+G S +V + P KP I ++ I+ W P+
Sbjct: 777 LQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQ--WHPPV 834
Query: 83 EKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTG 142
+ G +QGY +K+ R + E + + T++ Y + A N G G
Sbjct: 835 D-TFGPLQGYRLKFGRKD--MEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFG 891
Query: 143 PSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNR-- 200
+ P P ++ + + L+W + + Y +LYR
Sbjct: 892 EEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIP 951
Query: 201 --QSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDG--SSSEQIRIPKISNAYAR 254
++ + T L D Y ++++ + G G S S Q R + +A+
Sbjct: 952 LLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAK 1009
Score = 37.4 bits (85), Expect = 0.015
Identities = 45/202 (22%), Positives = 82/202 (40%), Gaps = 29/202 (14%)
Query: 25 PFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFA-----RSLSATDIEVFWA 79
P + ++VKV +KG GP+SP+ + T P +FA +++ T + + W
Sbjct: 973 PDTTYDVKVRAHTSKGPGPYSPSV------QFRTLPVDQVFAKNFHVKAVMKTSVLLSWE 1026
Query: 80 SPLEKNRGRIQGYEVKYWRHEDKEENARKIRTV-GNQTSTKITNLKGSVLYHLAVKAYNS 138
P +N +++ Y ++ + + V G T I NLK Y + +
Sbjct: 1027 IP--ENYNSAMPFKILY-------DDGKMVEEVDGRATQKLIVNLKPEKSYSFVL---TN 1074
Query: 139 AGTGPSSATVNVTTRKPPP--SQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLY 196
G VT + P P I + D I + +V A +N +KGY ++
Sbjct: 1075 RGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANEN---IKGYYIII 1131
Query: 197 RWNRQSSTSVIETNKTSVELSL 218
++S I+ ++ E+ L
Sbjct: 1132 VPLKKSRGKFIKPWESPDEMEL 1153
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform
3 precursor [Homo sapiens]
Length = 1903
Score = 94.0 bits (232), Expect = 1e-19
Identities = 72/253 (28%), Positives = 114/253 (45%), Gaps = 10/253 (3%)
Query: 25 PFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEK 84
P+S +E +V NN G GP S + ++E+ P+ P + AR LS+T I V W P E
Sbjct: 385 PYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEP 444
Query: 85 NRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPS 144
N G+IQGY V Y + N V + T I NL Y + V A+ S G GP
Sbjct: 445 N-GQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPL 503
Query: 145 SATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSST 204
S+ + V T+ P QP S++ I+L+W ++ + Y+++Y+
Sbjct: 504 SSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRS----DTIANYELVYKDGEHGEE 559
Query: 205 SVIETNK-TSVEL-SLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGSGASTSN 262
I TS L L + Y + S G G+S+ +I ++ S
Sbjct: 560 QRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEI---SARTMQSKPSAPPQDI 616
Query: 263 ACTLSAISTIMIS 275
+CT + ++I++S
Sbjct: 617 SCTSPSSTSILVS 629
Score = 71.6 bits (174), Expect = 7e-13
Identities = 47/190 (24%), Positives = 95/190 (50%), Gaps = 9/190 (4%)
Query: 11 ADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLS 70
+D ++Y+ E + ++ + + V + G GP S + ++ + E+ P+ PP + +++
Sbjct: 667 SDTTKYLL--EQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVN 724
Query: 71 ATDIEVFWASPL-EKNRGRIQGYEVKYWRHEDKEENAR---KIRTVGNQTSTKITNLKGS 126
+T ++V W SP+ K G+I+GY+V Y R E+ E + K + + I+ L+
Sbjct: 725 STSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQDMIISGLQPE 784
Query: 127 VLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNE 186
Y L V AY + G G S V+T P + P +I ++ + ++ W +D
Sbjct: 785 TSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGK-PRLVINHTQMNTALIQWH--PPVDTF 841
Query: 187 SEVKGYKVLY 196
++GY++ +
Sbjct: 842 GPLQGYRLKF 851
Score = 70.1 bits (170), Expect = 2e-12
Identities = 50/235 (21%), Positives = 104/235 (44%), Gaps = 11/235 (4%)
Query: 18 FRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVF 77
+R + + P S + ++ + +G G + + + +P+ PP I S S+T I V
Sbjct: 570 YRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVS 629
Query: 78 W-ASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTST-KITNLKGSVLYHLAVKA 135
W P+EK G I Y +KY + +++ +I + + T+ + L+ Y + V A
Sbjct: 630 WQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTA 689
Query: 136 YNSAGTGPSSATVNVTTRKPPPSQPPGNI-IWNSSDSKIILNWDQVKALDNESEVKGYKV 194
+ G GP S +V + T + PS PP + + + + + ++W +++GY+V
Sbjct: 690 HTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQV 749
Query: 195 LY--------RWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSE 241
Y + ++ + + L + Y + + ++ GDG+ S+
Sbjct: 750 HYVRMENGEPKGQPMLKDVMLADAQDMIISGLQPETSYSLTVTAYTTKGDGARSK 804
Score = 45.4 bits (106), Expect = 5e-05
Identities = 51/257 (19%), Positives = 95/257 (36%), Gaps = 13/257 (5%)
Query: 4 MLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPAS 63
ML + ADA + + P + + + V + KG+G S +V + P KP
Sbjct: 764 MLKDVMLADAQDMII--SGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLV 821
Query: 64 IFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNL 123
I ++ I+ W P++ G +QGY +K+ R + E + + T++
Sbjct: 822 INHTQMNTALIQ--WHPPVD-TFGPLQGYRLKFGRKD--MEPLTTLEFSEKEDHFTATDI 876
Query: 124 KGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKAL 183
Y + A N G G + P P ++ + + L+W
Sbjct: 877 HKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLA 936
Query: 184 DNESEVKGYKVLYRWNR----QSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDG-- 237
+ + Y +LYR ++ + T L D Y ++++ + G G
Sbjct: 937 ERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGPY 996
Query: 238 SSSEQIRIPKISNAYAR 254
S S Q R + +A+
Sbjct: 997 SPSVQFRTLPVDQVFAK 1013
Score = 37.4 bits (85), Expect = 0.015
Identities = 45/202 (22%), Positives = 82/202 (40%), Gaps = 29/202 (14%)
Query: 25 PFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFA-----RSLSATDIEVFWA 79
P + ++VKV +KG GP+SP+ + T P +FA +++ T + + W
Sbjct: 977 PDTTYDVKVRAHTSKGPGPYSPSV------QFRTLPVDQVFAKNFHVKAVMKTSVLLSWE 1030
Query: 80 SPLEKNRGRIQGYEVKYWRHEDKEENARKIRTV-GNQTSTKITNLKGSVLYHLAVKAYNS 138
P +N +++ Y ++ + + V G T I NLK Y + +
Sbjct: 1031 IP--ENYNSAMPFKILY-------DDGKMVEEVDGRATQKLIVNLKPEKSYSFVL---TN 1078
Query: 139 AGTGPSSATVNVTTRKPPP--SQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLY 196
G VT + P P I + D I + +V A +N +KGY ++
Sbjct: 1079 RGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANEN---IKGYYIII 1135
Query: 197 RWNRQSSTSVIETNKTSVELSL 218
++S I+ ++ E+ L
Sbjct: 1136 VPLKKSRGKFIKPWESPDEMEL 1157
>gi|104487002 protein tyrosine phosphatase, receptor type, D isoform
5 precursor [Homo sapiens]
Length = 1502
Score = 93.2 bits (230), Expect = 2e-19
Identities = 68/232 (29%), Positives = 106/232 (45%), Gaps = 7/232 (3%)
Query: 25 PFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEK 84
P+S +E +V NN G GP S + ++E+ P+ P + AR LS+T I V W P E
Sbjct: 382 PYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEP 441
Query: 85 NRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPS 144
N G+IQGY V Y + N V + T I NL Y + V A+ S G GP
Sbjct: 442 N-GQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPL 500
Query: 145 SATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSST 204
S+ + V T+ P QP S++ I+L+W ++ + Y+++Y+
Sbjct: 501 SSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRS----DTIANYELVYKDGEHGEE 556
Query: 205 SVIETNK-TSVEL-SLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYAR 254
I TS L L + Y + S G G+S+ +I + + +A+
Sbjct: 557 QRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAK 608
>gi|18860894 protein tyrosine phosphatase, receptor type, D isoform
4 precursor [Homo sapiens]
Length = 1501
Score = 93.2 bits (230), Expect = 2e-19
Identities = 68/232 (29%), Positives = 106/232 (45%), Gaps = 7/232 (3%)
Query: 25 PFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEK 84
P+S +E +V NN G GP S + ++E+ P+ P + AR LS+T I V W P E
Sbjct: 385 PYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEP 444
Query: 85 NRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPS 144
N G+IQGY V Y + N V + T I NL Y + V A+ S G GP
Sbjct: 445 N-GQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPL 503
Query: 145 SATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSST 204
S+ + V T+ P QP S++ I+L+W ++ + Y+++Y+
Sbjct: 504 SSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRS----DTIANYELVYKDGEHGEE 559
Query: 205 SVIETNK-TSVEL-SLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYAR 254
I TS L L + Y + S G G+S+ +I + + +A+
Sbjct: 560 QRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSMFAK 611
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 92.4 bits (228), Expect = 4e-19
Identities = 54/190 (28%), Positives = 93/190 (48%), Gaps = 5/190 (2%)
Query: 8 LASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFAR 67
L+ ++Y N + H +E+++ V+N GEGP SP V+ E PT P ++
Sbjct: 1576 LSRPSLTQYELDNLNKH--RRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVH 1633
Query: 68 SLSATDIEVFW-ASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGS 126
+AT ++V W PL+ G IQGY++ +W + R + S K+ NL G
Sbjct: 1634 GATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGY 1693
Query: 127 VLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNE 186
Y ++V A+N+AG GP S T++ PS P + + + ++W+ + +
Sbjct: 1694 TAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGI 1753
Query: 187 SEVKGYKVLY 196
E GY+++Y
Sbjct: 1754 LE--GYRLVY 1761
Score = 77.8 bits (190), Expect = 1e-14
Identities = 66/249 (26%), Positives = 118/249 (47%), Gaps = 12/249 (4%)
Query: 3 WMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFS-PTTVVYSAEEEPTKPP 61
W+L S + ++PF+ + ++ N G P S P+ + + + P P
Sbjct: 1041 WLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAP 1100
Query: 62 ASIFARSLSATDIEVFWAS-PLEKNRGRIQ--GYEVKYWRHEDKEENARKIRTVGNQTST 118
A++ R+ S T + + W P + G + GY++KY R + + + +
Sbjct: 1101 ANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDY 1160
Query: 119 KITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNI-IWNSSDSKIILNW 177
I +L+ Y + V+A+N+ G+GP S TV TR+ PS P N+ ++ S +++ W
Sbjct: 1161 TIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRW 1220
Query: 178 DQVKALDNESEVKGYKVLYRWNRQSSTS----VIETNKT-SVELS-LPFDEDYIIEIKPF 231
+V D V GYKV+Y+ + S T ++E N + S +L+ L Y +++ F
Sbjct: 1221 SEVPEADRNGLVLGYKVMYK-EKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAF 1279
Query: 232 SDGGDGSSS 240
+ GDGS S
Sbjct: 1280 TRIGDGSPS 1288
Score = 68.6 bits (166), Expect = 6e-12
Identities = 57/207 (27%), Positives = 96/207 (46%), Gaps = 12/207 (5%)
Query: 21 ESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWAS 80
E + ++ + V+V FN G GP+S T V + E P+ P ++ A + +++ + V W+
Sbjct: 1163 EDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSE 1222
Query: 81 PLEKNR-GRIQGYEVKYWRHEDKEENARKIRTVGNQT-STKITNLKGSVLYHLAVKAYNS 138
E +R G + GY+V Y + +D + R GN + S ++T L VLY + V A+
Sbjct: 1223 VPEADRNGLVLGYKVMY-KEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTR 1281
Query: 139 AGTG-PSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYR 197
G G PS + T P P G + + + L W Q A N + Y++ +R
Sbjct: 1282 IGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIW-QPPAAPN-GIILAYQITHR 1339
Query: 198 WNRQSSTSVIETNKTSVELSLPFDEDY 224
N ++ N +VE+ P Y
Sbjct: 1340 LNTTTA------NTATVEVLAPSARQY 1360
Score = 67.8 bits (164), Expect = 1e-11
Identities = 62/245 (25%), Positives = 105/245 (42%), Gaps = 11/245 (4%)
Query: 7 VLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTV-VYSAEEEPTKPPASIF 65
+LAS D + + P ++ ++ N+ G+G FS T V EE PT PP ++
Sbjct: 639 LLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVI 698
Query: 66 ARSLSATDIEVFWASPLEKNR-GRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLK 124
A + I + W P E ++ G ++GY ++Y K T + + + +L
Sbjct: 699 ASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLI 758
Query: 125 GSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKII-LNWDQVKAL 183
Y + V AYNSAG G S+ V T + P+ PPGN+ +++S I W+
Sbjct: 759 IWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQ 818
Query: 184 DNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFD--------EDYIIEIKPFSDGG 235
+GYK++ Q + T + + + S+ +Y + F+ G
Sbjct: 819 FINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPG 878
Query: 236 DGSSS 240
DG S
Sbjct: 879 DGPRS 883
Score = 63.2 bits (152), Expect = 3e-10
Identities = 52/221 (23%), Positives = 98/221 (44%), Gaps = 12/221 (5%)
Query: 29 FEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEK-NRG 87
+E++V +N+ G G +S ++ + PT PP ++ A + ++T I W +P + G
Sbjct: 763 YEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFING 822
Query: 88 RIQGYEVKYWRHEDKEENARKIRTVGNQTSTK---ITNLKGSVLYHLAVKAYNSAGTGPS 144
QGY++ W E +EE Q S ++ LK Y +V + + G GP
Sbjct: 823 INQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPR 882
Query: 145 SATVNVTTRKPPPSQPPGNIIWNS-SDSKIILNWDQVKALDNESEVKGYKVLY-RWNRQS 202
S V T + P P G++ ++ D+ + ++W + + + GY++ + +NR +
Sbjct: 883 STPQLVRTHEDVPG-PVGHLSFSEILDTSLKVSWQEPG--EKNGILTGYRISWEEYNRTN 939
Query: 203 STSVIETNKTSVE---LSLPFDEDYIIEIKPFSDGGDGSSS 240
+ ++E L Y IE+ + G G S
Sbjct: 940 TRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVS 980
Score = 57.4 bits (137), Expect = 1e-08
Identities = 52/223 (23%), Positives = 87/223 (39%), Gaps = 13/223 (5%)
Query: 29 FEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRGR 88
+EV+V F G+G S ++ ++ PP I + T + + W P N G
Sbjct: 1272 YEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPN-GI 1330
Query: 89 IQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATV 148
I Y++ + + A + T LK +Y + A G G ++ +
Sbjct: 1331 ILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEAL 1390
Query: 149 NVTTRKPPPSQPPGNIIWNSSDSK---IILNWDQVKALDNESEVKGYKVLY------RWN 199
VTT K QPP + D + ++L+W+ D S V+ Y + RW
Sbjct: 1391 VVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWE--PGSDGLSPVRYYTIQTRELPSGRWA 1448
Query: 200 RQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQ 242
S++ + V+ PF Y +K +D GD SE+
Sbjct: 1449 LHSASVSHNASSFIVDRLKPF-TSYKFRVKATNDIGDSEFSEE 1490
Score = 50.8 bits (120), Expect = 1e-06
Identities = 44/164 (26%), Positives = 69/164 (42%), Gaps = 5/164 (3%)
Query: 2 IWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPP 61
+ M+T + S +V + F+ + V F G+GP S +V + E+ P P
Sbjct: 840 VTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVP-GPV 898
Query: 62 ASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQT-STKI 120
+ + T ++V W P EKN G + GY + + E N R + N T ++
Sbjct: 899 GHLSFSEILDTSLKVSWQEPGEKN-GILTGYRISW--EEYNRTNTRVTHYLPNVTLEYRV 955
Query: 121 TNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNI 164
T L Y + V A S G G SA+ + P PP N+
Sbjct: 956 TGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNL 999
Score = 45.8 bits (107), Expect = 4e-05
Identities = 52/282 (18%), Positives = 109/282 (38%), Gaps = 31/282 (10%)
Query: 18 FRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVF 77
+R + + + ++V +KG+G S +T+ E PP ++ ++ +
Sbjct: 953 YRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSV--- 1009
Query: 78 WASPLEKNRGRIQGYEVKYWRHE------DKEENARKIRTVGNQ---TSTKITNLKGSVL 128
L+ G + W E + E I + N+ S ++ +L
Sbjct: 1010 ---TLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTC 1066
Query: 129 YHLAVKAYNSAGTG-PSSATVNVTTRKPPPSQPPGNI-IWNSSDSKIILNWDQVKALD-- 184
Y ++ N GT PS + + T + PP P N+ + +S++ + L W + ++
Sbjct: 1067 YSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYN 1126
Query: 185 NESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDE-----DYIIEIKPFSDGGDGSS 239
E GYK+ Y + ++ + VE ++ +Y ++++ F+ G G
Sbjct: 1127 GNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPW 1186
Query: 240 SEQIRIPKISNAYARGSGASTSNACTLSAISTIMISLTARSS 281
S+ + +S +SA++T S+ R S
Sbjct: 1187 SQTV-------VGRTRESVPSSGPTNVSALATTSSSMLVRWS 1221
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform
1 precursor [Homo sapiens]
Length = 1907
Score = 85.9 bits (211), Expect = 4e-17
Identities = 71/256 (27%), Positives = 114/256 (44%), Gaps = 15/256 (5%)
Query: 25 PFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEK 84
PFS + +V N+ G GP S + E+ P+ PP + AR LSA+ + V W P E
Sbjct: 381 PFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEP 440
Query: 85 NRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPS 144
N G ++GY V Y + NA T + +L + Y L V A+ + G GP
Sbjct: 441 N-GLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPP 499
Query: 145 SATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRW-----N 199
S T+ V T++ P+QP SD++I L+W L + + Y+++Y W +
Sbjct: 500 SPTIQVKTQQGVPAQPADFQAEVESDTRIQLSW----LLPPQERIIMYELVY-WAAEDED 554
Query: 200 RQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGSGAS 259
+Q + T+ ++E L D Y ++ SD G G + I + A + S
Sbjct: 555 QQHKVTFDPTSSYTLE-DLKPDTLYRFQLAARSDMGVGVFTPTI---EARTAQSTPSAPP 610
Query: 260 TSNACTLSAISTIMIS 275
C +T+ +S
Sbjct: 611 QKVMCVSMGSTTVRVS 626
Score = 71.6 bits (174), Expect = 7e-13
Identities = 60/279 (21%), Positives = 117/279 (41%), Gaps = 35/279 (12%)
Query: 21 ESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWA- 79
E + P + + ++ ++ G G F+PT +A+ P+ PP + S+ +T + V W
Sbjct: 570 EDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVP 629
Query: 80 SPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQ-TSTKITNLKGSVLYHLAVKAYNS 138
P + G I Y V Y + ++ + + + +S + L+ Y + V+A+
Sbjct: 630 PPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTD 689
Query: 139 AGTGPSSATVNVTTRKPPPSQPPGNI-IWNSSDSKIILNWDQVKALDNESEVKGYKVLY- 196
G GP S+ V V T + PS PP + + + + + + W +++GY+V Y
Sbjct: 690 VGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYV 749
Query: 197 ---------------------RWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGG 235
+W + S E +T++ P + Y + + ++ G
Sbjct: 750 RLENGEPRGLPIIQDVMLAEAQWRPEES----EDYETTISGLTP-ETTYSVTVAAYTTKG 804
Query: 236 DGSSSEQIRIPKISNAYARGSGASTSNACTLSAISTIMI 274
DG+ S+ PKI G T T +A++T ++
Sbjct: 805 DGARSK----PKIVTTTGAVPGRPTMMIST-TAMNTALL 838
Score = 67.4 bits (163), Expect = 1e-11
Identities = 50/176 (28%), Positives = 81/176 (46%), Gaps = 7/176 (3%)
Query: 22 SVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASP 81
S+ P + ++V F G+GP SPT V + + P + PA A S T I++ W P
Sbjct: 477 SLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQ-PADFQAEVESDTRIQLSWLLP 535
Query: 82 LEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGT 141
++ RI YE+ YW ED+++ + T +S + +LK LY + A + G
Sbjct: 536 PQE---RIIMYELVYWAAEDEDQQHKV--TFDPTSSYTLEDLKPDTLYRFQLAARSDMGV 590
Query: 142 GPSSATVNVTTRKPPPSQPPGNIIWNSSDSKII-LNWDQVKALDNESEVKGYKVLY 196
G + T+ T + PS PP ++ S S + ++W A + Y V Y
Sbjct: 591 GVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAY 646
Score = 57.0 bits (136), Expect = 2e-08
Identities = 56/234 (23%), Positives = 94/234 (40%), Gaps = 10/234 (4%)
Query: 25 PFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEK 84
P + + V V + KG+G S +V + P +P I +++ ++ W P E
Sbjct: 789 PETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQ--WHPPKEL 846
Query: 85 NRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPS 144
G + GY ++Y R ++ N I + +T L Y + A N AG G
Sbjct: 847 P-GELLGYRLQYCRADEARPNT--IDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLG-E 902
Query: 145 SATVNVTTRKPPPSQPPGNI-IWNSSDSKIILNWDQVKALDNESEVKGYKVLYR-WNRQS 202
+ T + PS P N+ + + S L WD + + Y V++R N Q
Sbjct: 903 EFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQ 962
Query: 203 STSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDG--SSSEQIRIPKISNAYAR 254
I T+ L D Y I+++ ++ G G S S Q R + +A+
Sbjct: 963 ELQNITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAK 1016
Score = 30.0 bits (66), Expect = 2.4
Identities = 17/69 (24%), Positives = 31/69 (44%), Gaps = 11/69 (15%)
Query: 18 FRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSA-----T 72
F + P + +++KV + +KG GP SP+ + T P +FA++ T
Sbjct: 973 FTLTGLKPDTTYDIKVRAWTSKGSGPLSPSI------QSRTMPVEQVFAKNFRVAAAMKT 1026
Query: 73 DIEVFWASP 81
+ + W P
Sbjct: 1027 SVLLSWEVP 1035
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform
2 precursor [Homo sapiens]
Length = 1898
Score = 85.9 bits (211), Expect = 4e-17
Identities = 71/256 (27%), Positives = 114/256 (44%), Gaps = 15/256 (5%)
Query: 25 PFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEK 84
PFS + +V N+ G GP S + E+ P+ PP + AR LSA+ + V W P E
Sbjct: 381 PFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEP 440
Query: 85 NRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPS 144
N G ++GY V Y + NA T + +L + Y L V A+ + G GP
Sbjct: 441 N-GLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPP 499
Query: 145 SATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRW-----N 199
S T+ V T++ P+QP SD++I L+W L + + Y+++Y W +
Sbjct: 500 SPTIQVKTQQGVPAQPADFQAEVESDTRIQLSW----LLPPQERIIMYELVY-WAAEDED 554
Query: 200 RQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGSGAS 259
+Q + T+ ++E L D Y ++ SD G G + I + A + S
Sbjct: 555 QQHKVTFDPTSSYTLE-DLKPDTLYRFQLAARSDMGVGVFTPTI---EARTAQSTPSAPP 610
Query: 260 TSNACTLSAISTIMIS 275
C +T+ +S
Sbjct: 611 QKVMCVSMGSTTVRVS 626
Score = 73.6 bits (179), Expect = 2e-13
Identities = 58/266 (21%), Positives = 114/266 (42%), Gaps = 18/266 (6%)
Query: 21 ESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWA- 79
E + P + + ++ ++ G G F+PT +A+ P+ PP + S+ +T + V W
Sbjct: 570 EDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVP 629
Query: 80 SPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQ-TSTKITNLKGSVLYHLAVKAYNS 138
P + G I Y V Y + ++ + + + +S + L+ Y + V+A+
Sbjct: 630 PPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTD 689
Query: 139 AGTGPSSATVNVTTRKPPPSQPPGNI-IWNSSDSKIILNWDQVKALDNESEVKGYKVLYR 197
G GP S+ V V T + PS PP + + + + + + W +++GY+V Y
Sbjct: 690 VGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYV 749
Query: 198 WNRQ---------SSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKI 248
+ E +T++ P + Y + + ++ GDG+ S+ PKI
Sbjct: 750 RLENGEPRGLPIIQDVMLAEAQETTISGLTP-ETTYSVTVAAYTTKGDGARSK----PKI 804
Query: 249 SNAYARGSGASTSNACTLSAISTIMI 274
G T T +A++T ++
Sbjct: 805 VTTTGAVPGRPTMMIST-TAMNTALL 829
Score = 67.4 bits (163), Expect = 1e-11
Identities = 50/176 (28%), Positives = 81/176 (46%), Gaps = 7/176 (3%)
Query: 22 SVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASP 81
S+ P + ++V F G+GP SPT V + + P + PA A S T I++ W P
Sbjct: 477 SLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQ-PADFQAEVESDTRIQLSWLLP 535
Query: 82 LEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGT 141
++ RI YE+ YW ED+++ + T +S + +LK LY + A + G
Sbjct: 536 PQE---RIIMYELVYWAAEDEDQQHKV--TFDPTSSYTLEDLKPDTLYRFQLAARSDMGV 590
Query: 142 GPSSATVNVTTRKPPPSQPPGNIIWNSSDSKII-LNWDQVKALDNESEVKGYKVLY 196
G + T+ T + PS PP ++ S S + ++W A + Y V Y
Sbjct: 591 GVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAY 646
Score = 57.0 bits (136), Expect = 2e-08
Identities = 56/234 (23%), Positives = 94/234 (40%), Gaps = 10/234 (4%)
Query: 25 PFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEK 84
P + + V V + KG+G S +V + P +P I +++ ++ W P E
Sbjct: 780 PETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQ--WHPPKEL 837
Query: 85 NRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPS 144
G + GY ++Y R ++ N I + +T L Y + A N AG G
Sbjct: 838 P-GELLGYRLQYCRADEARPNT--IDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLG-E 893
Query: 145 SATVNVTTRKPPPSQPPGNI-IWNSSDSKIILNWDQVKALDNESEVKGYKVLYR-WNRQS 202
+ T + PS P N+ + + S L WD + + Y V++R N Q
Sbjct: 894 EFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQ 953
Query: 203 STSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDG--SSSEQIRIPKISNAYAR 254
I T+ L D Y I+++ ++ G G S S Q R + +A+
Sbjct: 954 ELQNITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAK 1007
Score = 30.0 bits (66), Expect = 2.4
Identities = 17/69 (24%), Positives = 31/69 (44%), Gaps = 11/69 (15%)
Query: 18 FRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSA-----T 72
F + P + +++KV + +KG GP SP+ + T P +FA++ T
Sbjct: 964 FTLTGLKPDTTYDIKVRAWTSKGSGPLSPSI------QSRTMPVEQVFAKNFRVAAAMKT 1017
Query: 73 DIEVFWASP 81
+ + W P
Sbjct: 1018 SVLLSWEVP 1026
>gi|104487611 protein tyrosine phosphatase, receptor type, sigma
isoform 4 precursor [Homo sapiens]
Length = 1505
Score = 84.7 bits (208), Expect = 8e-17
Identities = 56/173 (32%), Positives = 86/173 (49%), Gaps = 5/173 (2%)
Query: 25 PFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEK 84
P S +E+ V N+ G+GP S + V + E+ P P ++ AR LSAT + V W P+E
Sbjct: 385 PNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEP 444
Query: 85 NRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPS 144
N G I+GY V Y + + V + T + +L Y + V A+ S G GP
Sbjct: 445 N-GLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPL 503
Query: 145 SATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYR 197
S + V T++ P QP S++ I L+W + ES +K Y++L+R
Sbjct: 504 SDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPR---QESIIK-YELLFR 552
Score = 55.8 bits (133), Expect = 4e-08
Identities = 47/193 (24%), Positives = 82/193 (42%), Gaps = 13/193 (6%)
Query: 59 KPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTST 118
K P + +AT I + W S N + Y ++Y ++ +I+ T
Sbjct: 324 KAPGTPMVTENTATSITITWDSG---NPDPVSYYVIEY--KSKSQDGPYQIKEDITTTRY 378
Query: 119 KITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNS-SDSKIILNW 177
I L + Y + V A NS G GP S +V T + P+ P N+ S + +I+ W
Sbjct: 379 SIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQW 438
Query: 178 DQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVEL-----SLPFDEDYIIEIKPFS 232
++ ++ ++GY+V Y + + + L SL DE Y + + F+
Sbjct: 439 EE--PVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFT 496
Query: 233 DGGDGSSSEQIRI 245
GDG S+ I++
Sbjct: 497 SVGDGPLSDPIQV 509
>gi|104487297 protein tyrosine phosphatase, receptor type, sigma
isoform 2 precursor [Homo sapiens]
Length = 1910
Score = 84.7 bits (208), Expect = 8e-17
Identities = 56/173 (32%), Positives = 86/173 (49%), Gaps = 5/173 (2%)
Query: 25 PFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEK 84
P S +E+ V N+ G+GP S + V + E+ P P ++ AR LSAT + V W P+E
Sbjct: 381 PNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEP 440
Query: 85 NRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPS 144
N G I+GY V Y + + V + T + +L Y + V A+ S G GP
Sbjct: 441 N-GLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPL 499
Query: 145 SATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYR 197
S + V T++ P QP S++ I L+W + ES +K Y++L+R
Sbjct: 500 SDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPR---QESIIK-YELLFR 548
Score = 76.3 bits (186), Expect = 3e-14
Identities = 66/244 (27%), Positives = 109/244 (44%), Gaps = 28/244 (11%)
Query: 21 ESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWAS 80
E++ ++ + + G GP S VV + E+ P+ PP + A +L+AT I V W S
Sbjct: 671 EALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRS 730
Query: 81 PLE-KNRGRIQGYEVKYWRHEDKE-ENARKIRTV--GNQTSTKITNLKGSVLYHLAVKAY 136
P + G+I+GY+V Y R E E +I+ V + ITNL+ Y + V AY
Sbjct: 731 PAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQEMVITNLQPETAYSITVAAY 790
Query: 137 NSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLY 196
G G S V T+ +P + + + + ++ W+ A E +V GY++
Sbjct: 791 TMKGDGARSKPKVVVTKGAVLGRPTLS-VQQTPEGSLLARWEP-PAGTAEDQVLGYRL-- 846
Query: 197 RWNRQSSTSVIETNKTSVELSLPFDED------------YIIEIKPFSDGGDG-SSSEQI 243
++ R+ ST + L P ED Y+ + S GG G ++E +
Sbjct: 847 QFGREDSTPL-------ATLEFPPSEDRYTASGVHKGATYVFRLAARSRGGLGEEAAEVL 899
Query: 244 RIPK 247
IP+
Sbjct: 900 SIPE 903
Score = 64.3 bits (155), Expect = 1e-10
Identities = 51/232 (21%), Positives = 101/232 (43%), Gaps = 11/232 (4%)
Query: 21 ESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFW-A 79
E + P + + ++ + +G G F+P + + +P+ PP + S+ +T I V W
Sbjct: 569 EDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRP 628
Query: 80 SPLEKNRGRIQGYEVKYWRHEDKEENARKIRTV-GNQTSTKITNLKGSVLYHLAVKAYNS 138
P E + G + GY V+Y ++ +++ + T + L+ Y + A+
Sbjct: 629 PPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTE 688
Query: 139 AGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKII-LNWDQVKALDNESEVKGYKVLY- 196
G GP S+ V V T + PS PP + + ++ I + W +++GY+V Y
Sbjct: 689 VGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHYV 748
Query: 197 -------RWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSE 241
R + ++ + V +L + Y I + ++ GDG+ S+
Sbjct: 749 RMEGAEARGPPRIKDVMLADAQEMVITNLQPETAYSITVAAYTMKGDGARSK 800
Score = 55.8 bits (133), Expect = 4e-08
Identities = 47/193 (24%), Positives = 82/193 (42%), Gaps = 13/193 (6%)
Query: 59 KPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTST 118
K P + +AT I + W S N + Y ++Y ++ +I+ T
Sbjct: 320 KAPGTPMVTENTATSITITWDSG---NPDPVSYYVIEY--KSKSQDGPYQIKEDITTTRY 374
Query: 119 KITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNS-SDSKIILNW 177
I L + Y + V A NS G GP S +V T + P+ P N+ S + +I+ W
Sbjct: 375 SIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQW 434
Query: 178 DQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVEL-----SLPFDEDYIIEIKPFS 232
++ ++ ++GY+V Y + + + L SL DE Y + + F+
Sbjct: 435 EE--PVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFT 492
Query: 233 DGGDGSSSEQIRI 245
GDG S+ I++
Sbjct: 493 SVGDGPLSDPIQV 505
Score = 52.4 bits (124), Expect = 4e-07
Identities = 44/170 (25%), Positives = 77/170 (45%), Gaps = 8/170 (4%)
Query: 29 FEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRGR 88
+ V+V F + G+GP S V + + P +P ++ A + S T I + W+ P +++
Sbjct: 484 YTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQP-MNLRAEARSETSITLSWSPPRQES--- 539
Query: 89 IQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATV 148
I YE+ + + E R T TS + +LK + Y + A + G G + V
Sbjct: 540 IIKYELLFREGDHGREVGR---TFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVV 596
Query: 149 NVTTRKPPPSQPPGNIIWNS-SDSKIILNWDQVKALDNESEVKGYKVLYR 197
T + PS PP ++ S + I+++W + + GY V YR
Sbjct: 597 RQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYR 646
Score = 32.7 bits (73), Expect = 0.37
Identities = 25/113 (22%), Positives = 45/113 (39%), Gaps = 11/113 (9%)
Query: 21 ESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWAS 80
+ + P + ++++V +G GPFSP V Y P + + + T + + W
Sbjct: 976 QGLKPDTAYDLQVRAHTRRGPGPFSP-PVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEF 1034
Query: 81 PLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAV 133
P N Y+++Y N + G T IT+LK Y+ +
Sbjct: 1035 P--DNYNSPTPYKIQY--------NGLTLDVDGRTTKKLITHLKPHTFYNFVL 1077
>gi|104487295 protein tyrosine phosphatase, receptor type, sigma
isoform 3 precursor [Homo sapiens]
Length = 1501
Score = 84.7 bits (208), Expect = 8e-17
Identities = 56/173 (32%), Positives = 86/173 (49%), Gaps = 5/173 (2%)
Query: 25 PFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEK 84
P S +E+ V N+ G+GP S + V + E+ P P ++ AR LSAT + V W P+E
Sbjct: 381 PNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEP 440
Query: 85 NRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPS 144
N G I+GY V Y + + V + T + +L Y + V A+ S G GP
Sbjct: 441 N-GLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPL 499
Query: 145 SATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYR 197
S + V T++ P QP S++ I L+W + ES +K Y++L+R
Sbjct: 500 SDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPR---QESIIK-YELLFR 548
Score = 55.8 bits (133), Expect = 4e-08
Identities = 47/193 (24%), Positives = 82/193 (42%), Gaps = 13/193 (6%)
Query: 59 KPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTST 118
K P + +AT I + W S N + Y ++Y ++ +I+ T
Sbjct: 320 KAPGTPMVTENTATSITITWDSG---NPDPVSYYVIEY--KSKSQDGPYQIKEDITTTRY 374
Query: 119 KITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNS-SDSKIILNW 177
I L + Y + V A NS G GP S +V T + P+ P N+ S + +I+ W
Sbjct: 375 SIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQW 434
Query: 178 DQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVEL-----SLPFDEDYIIEIKPFS 232
++ ++ ++GY+V Y + + + L SL DE Y + + F+
Sbjct: 435 EE--PVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFT 492
Query: 233 DGGDGSSSEQIRI 245
GDG S+ I++
Sbjct: 493 SVGDGPLSDPIQV 505
>gi|104487006 protein tyrosine phosphatase, receptor type, sigma
isoform 1 precursor [Homo sapiens]
Length = 1948
Score = 84.7 bits (208), Expect = 8e-17
Identities = 56/173 (32%), Positives = 86/173 (49%), Gaps = 5/173 (2%)
Query: 25 PFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEK 84
P S +E+ V N+ G+GP S + V + E+ P P ++ AR LSAT + V W P+E
Sbjct: 394 PNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEP 453
Query: 85 NRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPS 144
N G I+GY V Y + + V + T + +L Y + V A+ S G GP
Sbjct: 454 N-GLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPL 512
Query: 145 SATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYR 197
S + V T++ P QP S++ I L+W + ES +K Y++L+R
Sbjct: 513 SDPIQVKTQQGVPGQPMNLRAEARSETSITLSWSPPR---QESIIK-YELLFR 561
Score = 73.2 bits (178), Expect = 2e-13
Identities = 66/253 (26%), Positives = 108/253 (42%), Gaps = 37/253 (14%)
Query: 21 ESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWAS 80
E++ ++ + + G GP S VV + E+ P+ PP + A +L+AT I V W S
Sbjct: 684 EALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRS 743
Query: 81 PLE-KNRGRIQGYEVKYWRHEDKEENA----RKIRTVGNQTSTK--------ITNLKGSV 127
P + G+I+GY+V Y R E E + + Q T ITNL+
Sbjct: 744 PAPGRQHGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPET 803
Query: 128 LYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNES 187
Y + V AY G G S V T+ +P + + + + ++ W+ A E
Sbjct: 804 AYSITVAAYTMKGDGARSKPKVVVTKGAVLGRPTLS-VQQTPEGSLLARWEP-PAGTAED 861
Query: 188 EVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDED------------YIIEIKPFSDGG 235
+V GY++ ++ R+ ST + L P ED Y+ + S GG
Sbjct: 862 QVLGYRL--QFGREDSTPL-------ATLEFPPSEDRYTASGVHKGATYVFRLAARSRGG 912
Query: 236 DG-SSSEQIRIPK 247
G ++E + IP+
Sbjct: 913 LGEEAAEVLSIPE 925
Score = 62.8 bits (151), Expect = 3e-10
Identities = 42/179 (23%), Positives = 81/179 (45%), Gaps = 3/179 (1%)
Query: 21 ESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFW-A 79
E + P + + ++ + +G G F+P + + +P+ PP + S+ +T I V W
Sbjct: 582 EDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAILVSWRP 641
Query: 80 SPLEKNRGRIQGYEVKYWRHEDKEENARKIRTV-GNQTSTKITNLKGSVLYHLAVKAYNS 138
P E + G + GY V+Y ++ +++ + T + L+ Y + A+
Sbjct: 642 PPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQYRITTVAHTE 701
Query: 139 AGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKII-LNWDQVKALDNESEVKGYKVLY 196
G GP S+ V V T + PS PP + + ++ I + W +++GY+V Y
Sbjct: 702 VGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQHGQIRGYQVHY 760
Score = 55.8 bits (133), Expect = 4e-08
Identities = 47/193 (24%), Positives = 82/193 (42%), Gaps = 13/193 (6%)
Query: 59 KPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTST 118
K P + +AT I + W S N + Y ++Y ++ +I+ T
Sbjct: 333 KAPGTPMVTENTATSITITWDSG---NPDPVSYYVIEY--KSKSQDGPYQIKEDITTTRY 387
Query: 119 KITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNS-SDSKIILNW 177
I L + Y + V A NS G GP S +V T + P+ P N+ S + +I+ W
Sbjct: 388 SIGGLSPNSEYEIWVSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQW 447
Query: 178 DQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVEL-----SLPFDEDYIIEIKPFS 232
++ ++ ++GY+V Y + + + L SL DE Y + + F+
Sbjct: 448 EE--PVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFT 505
Query: 233 DGGDGSSSEQIRI 245
GDG S+ I++
Sbjct: 506 SVGDGPLSDPIQV 518
Score = 52.4 bits (124), Expect = 4e-07
Identities = 44/170 (25%), Positives = 77/170 (45%), Gaps = 8/170 (4%)
Query: 29 FEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRGR 88
+ V+V F + G+GP S V + + P +P ++ A + S T I + W+ P +++
Sbjct: 497 YTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQP-MNLRAEARSETSITLSWSPPRQES--- 552
Query: 89 IQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATV 148
I YE+ + + E R T TS + +LK + Y + A + G G + V
Sbjct: 553 IIKYELLFREGDHGREVGR---TFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVV 609
Query: 149 NVTTRKPPPSQPPGNIIWNS-SDSKIILNWDQVKALDNESEVKGYKVLYR 197
T + PS PP ++ S + I+++W + + GY V YR
Sbjct: 610 RQRTLQSKPSAPPQDVKCVSVRSTAILVSWRPPPPETHNGALVGYSVRYR 659
Score = 32.7 bits (73), Expect = 0.37
Identities = 25/113 (22%), Positives = 45/113 (39%), Gaps = 11/113 (9%)
Query: 21 ESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWAS 80
+ + P + ++++V +G GPFSP V Y P + + + T + + W
Sbjct: 998 QGLKPDTAYDLQVRAHTRRGPGPFSP-PVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEF 1056
Query: 81 PLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAV 133
P N Y+++Y N + G T IT+LK Y+ +
Sbjct: 1057 P--DNYNSPTPYKIQY--------NGLTLDVDGRTTKKLITHLKPHTFYNFVL 1099
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 84.3 bits (207), Expect = 1e-16
Identities = 50/178 (28%), Positives = 89/178 (50%), Gaps = 5/178 (2%)
Query: 25 PFSPFEVKVGVFNNKGEGPFSPTT-VVYSAEEEPTKPPASIFARSLSATDIEVFWAS-PL 82
P++ + ++ N G P+SP++ V+ + + P P S+ R+ S T + + W P
Sbjct: 1140 PYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLPD 1199
Query: 83 EKNRGRIQ--GYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAG 140
+ G + GY +KYWR + + ++ + + I L+ + Y L ++A+N+ G
Sbjct: 1200 SQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQAFNAVG 1259
Query: 141 TGPSSATVNVTTRKPPPSQPPGNIIWNS-SDSKIILNWDQVKALDNESEVKGYKVLYR 197
GP S V TR+ PS P N+ + S ++I+L W V D + GYK+L+R
Sbjct: 1260 AGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFR 1317
Score = 84.0 bits (206), Expect = 1e-16
Identities = 67/289 (23%), Positives = 125/289 (43%), Gaps = 42/289 (14%)
Query: 21 ESVHPFSPFEVKVGVFNNKGEGPFSPTT-VVYSAEEEPTKPPASIFARSLSATDIEVFWA 79
+ + PF+ +++++ N+ G+ FS T V + ++ P +PP S+ A + + + + W
Sbjct: 1541 DRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQ 1600
Query: 80 SPLEKN-RGRIQGYEVKYWRHEDKEENARKIRTVGN----------------------QT 116
P +++ G +QGY + Y E + + + +T+ N T
Sbjct: 1601 PPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTST 1660
Query: 117 STKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNI-IWNSSDSKIIL 175
++T+LK Y + + AYN G P+SA V V + P+ P N+ + + S++ +
Sbjct: 1661 MCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEV 1720
Query: 176 NWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVEL---------SLPFDEDYII 226
WD ++GYK+ Y W S ET K V +L Y++
Sbjct: 1721 TWDPPPPESQNGNIQGYKIYY-WEADSQN---ETEKMKVLFLPEPVVRLKNLTSHTKYLV 1776
Query: 227 EIKPFSDGGDGSSSEQIRIPKISNAYARGSGASTSNACTLSAISTIMIS 275
I F+ GDG S+ P+ + GA + A + +T+ +S
Sbjct: 1777 SISAFNAAGDGPKSD----PQQGRTHQAAPGAPSFLAFSEITSTTLNVS 1821
Score = 77.8 bits (190), Expect = 1e-14
Identities = 45/169 (26%), Positives = 79/169 (46%), Gaps = 3/169 (1%)
Query: 29 FEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFW-ASPLEKNRG 87
+EV + +N GE P S V+ E P P ++ L+A+ +EV W P E G
Sbjct: 1673 YEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNG 1732
Query: 88 RIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSAT 147
IQGY++ YW + + E + + ++ NL Y +++ A+N+AG GP S
Sbjct: 1733 NIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKSDP 1792
Query: 148 VNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLY 196
T + P P + + + ++W + A + ++GY+V+Y
Sbjct: 1793 QQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAAN--GILQGYRVVY 1839
Score = 66.6 bits (161), Expect = 2e-11
Identities = 49/183 (26%), Positives = 85/183 (46%), Gaps = 6/183 (3%)
Query: 18 FRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVF 77
F E + + +E+++ FN G GP+S + E P+ P ++ A ++S+T I +
Sbjct: 1237 FTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLT 1296
Query: 78 WAS-PLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQT-STKITNLKGSVLYHLAVKA 135
W S P + G I GY++ + R +D + R GN T S + L+ VLY L V A
Sbjct: 1297 WTSVPEQDQNGLILGYKILF-RAKDLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLA 1355
Query: 136 YNSAGTG-PSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKV 194
+ G G PS+ + T+ P P + + + + W + + + GY++
Sbjct: 1356 FTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPE--EPNGIILGYQI 1413
Query: 195 LYR 197
YR
Sbjct: 1414 AYR 1416
Score = 64.7 bits (156), Expect = 9e-11
Identities = 48/199 (24%), Positives = 88/199 (44%), Gaps = 10/199 (5%)
Query: 26 FSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEK- 84
++ +E++V +N G G FS Y+ + PT PP ++ ++++T I+ W P ++
Sbjct: 838 WTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQF 897
Query: 85 NRGRIQGYEVKYWRHEDKEENARKIRTVG----NQTSTKITNLKGSVLYHLAVKAYNSAG 140
G QGY++ W + E A + T+ ITNLK Y +V + + G
Sbjct: 898 INGINQGYKLLAWPADAPE--AVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPG 955
Query: 141 TGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYR-WN 199
GP S V T++ P D+ + ++W + L+ + GY++ + +
Sbjct: 956 DGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQE--PLEKNGIITGYQISWEVYG 1013
Query: 200 RQSSTSVIETNKTSVELSL 218
R S N T+ E +
Sbjct: 1014 RNDSRLTHTLNSTTHEYKI 1032
Score = 57.8 bits (138), Expect = 1e-08
Identities = 49/174 (28%), Positives = 77/174 (44%), Gaps = 3/174 (1%)
Query: 25 PFSPFEVKVGVFNNKGEGPFSP-TTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLE 83
P ++ +V N G G +S T+ + EE P+ PP +I A + I V W P E
Sbjct: 735 PARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPE 794
Query: 84 -KNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTG 142
++ G ++GY ++Y E ++ T +T+L Y + V AYN AG G
Sbjct: 795 TEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLG 854
Query: 143 PSSATVNVTTRKPPPSQPPGNIIWNSSDSKII-LNWDQVKALDNESEVKGYKVL 195
S V T + P+ PP N+ + +S I W+ +GYK+L
Sbjct: 855 VFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLL 908
Score = 53.5 bits (127), Expect = 2e-07
Identities = 45/154 (29%), Positives = 70/154 (45%), Gaps = 6/154 (3%)
Query: 26 FSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKN 85
F+ + V F G+GP S +V++ E++P F L T ++V W PLEKN
Sbjct: 941 FTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILD-TSLKVSWQEPLEKN 999
Query: 86 RGRIQGYEVKYWRHEDKEENARKIRTVGNQTST-KITNLKGSVLYHLAVKAYNSAGTG-P 143
G I GY++ W + ++ R T+ + T KI L Y + V A + GTG
Sbjct: 1000 -GIITGYQIS-WEVYGRNDS-RLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLV 1056
Query: 144 SSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNW 177
+S+T++ P P +I N S L +
Sbjct: 1057 TSSTISSGVPPDLPGAPSNLVISNISPRSATLQF 1090
Score = 44.3 bits (103), Expect = 1e-04
Identities = 42/167 (25%), Positives = 70/167 (41%), Gaps = 8/167 (4%)
Query: 17 VFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEV 76
V R +++ + + V + FN G+GP S + + P P F+ +++T + V
Sbjct: 1762 VVRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFS-EITSTTLNV 1820
Query: 77 FWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTV---GN-QTSTKITNLKGSVLYHLA 132
W P N G +QGY V Y + K+ TV GN Q K+ +L V Y
Sbjct: 1821 SWGEPAAAN-GILQGYRVVY-EPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFR 1878
Query: 133 VKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQ 179
V+A A + + P P +++ S S++ L W +
Sbjct: 1879 VQARTITYGPELQANITAGPAEGSPGS-PRDVLVTKSASELTLQWTE 1924
Score = 41.2 bits (95), Expect = 0.001
Identities = 33/126 (26%), Positives = 55/126 (43%), Gaps = 12/126 (9%)
Query: 78 WASPLEKNRGRIQGYEVKYWRHEDKEENAR---KIRTVGNQ-TSTKITNLKGSVLYHLAV 133
W P + N + Y+ E E N+ + VG + T ++ L + Y V
Sbjct: 690 WVRPFDGNS------PILYYIVELSENNSPWKVHLSNVGPEMTGVTVSGLTPARTYQFRV 743
Query: 134 KAYNSAGTGPSSA-TVNVTTRKPPPSQPPGNIIWNS-SDSKIILNWDQVKALDNESEVKG 191
A N G G SA T + + PPS PP NI+ + ++ I++ W ++ ++G
Sbjct: 744 CAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRG 803
Query: 192 YKVLYR 197
Y + YR
Sbjct: 804 YILRYR 809
>gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo
sapiens]
Length = 1248
Score = 81.6 bits (200), Expect = 7e-16
Identities = 50/178 (28%), Positives = 89/178 (50%), Gaps = 10/178 (5%)
Query: 26 FSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWAS-PLEK 84
F P+E+KV N++G+GP T+ YS E+ P P L+++ + V W L +
Sbjct: 776 FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQ 835
Query: 85 NRGRIQGYEVKYWRHEDKEENARK------IRTVGNQTSTKITNLKGSVLYHLAVKAYNS 138
+G ++GY V YWR + +++++ + N TS ++ L+ YHL V+A+N
Sbjct: 836 VKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNG 895
Query: 139 AGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLY 196
G+GP+S +T + P P + S++ ++L W L + + GY + Y
Sbjct: 896 RGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQ--PPLSHNGVLTGYVLSY 950
Score = 47.8 bits (112), Expect = 1e-05
Identities = 38/135 (28%), Positives = 67/135 (49%), Gaps = 11/135 (8%)
Query: 69 LSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVG----NQTSTKITNLK 124
L+ + + V W SP E + I+ Y++++ EDKE K ++G NQTST + L
Sbjct: 621 LTQSQVRVSW-SPAEDHNAPIEKYDIEF---EDKEMAPEKWYSLGKVPGNQTSTTL-KLS 675
Query: 125 GSVLYHLAVKAYNSAGTG-PSSATVNVTTRKPPPSQPPGNIIWNSSD-SKIILNWDQVKA 182
V Y V A N G G PS + V T + P + P ++ ++ + +++ W ++
Sbjct: 676 PYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRW 735
Query: 183 LDNESEVKGYKVLYR 197
+D + Y+V +R
Sbjct: 736 MDWNAPQVQYRVQWR 750
Score = 42.4 bits (98), Expect = 5e-04
Identities = 36/156 (23%), Positives = 65/156 (41%), Gaps = 5/156 (3%)
Query: 23 VHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPL 82
+ P+S + ++V FN +G GP S T +S E P ++ S T + + W PL
Sbjct: 880 LRPYSSYHLEVQAFNGRGSGPASEFT--FSTPEGVPGHPEALHLECQSNTSLLLRWQPPL 937
Query: 83 EKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTST-KITNLKGSVLYHLAVKAYNSAGT 141
N G + GY + Y ++ + + T +T+L + Y ++A G
Sbjct: 938 SHN-GVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGP 996
Query: 142 GPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNW 177
G + T S GNI + ++ +++W
Sbjct: 997 GEAIVREGGTMALSGISD-FGNISATAGENYSVVSW 1031
>gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo
sapiens]
Length = 1253
Score = 81.6 bits (200), Expect = 7e-16
Identities = 50/178 (28%), Positives = 89/178 (50%), Gaps = 10/178 (5%)
Query: 26 FSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWAS-PLEK 84
F P+E+KV N++G+GP T+ YS E+ P P L+++ + V W L +
Sbjct: 781 FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQ 840
Query: 85 NRGRIQGYEVKYWRHEDKEENARK------IRTVGNQTSTKITNLKGSVLYHLAVKAYNS 138
+G ++GY V YWR + +++++ + N TS ++ L+ YHL V+A+N
Sbjct: 841 VKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNG 900
Query: 139 AGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLY 196
G+GP+S +T + P P + S++ ++L W L + + GY + Y
Sbjct: 901 RGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQ--PPLSHNGVLTGYVLSY 955
Score = 47.8 bits (112), Expect = 1e-05
Identities = 38/135 (28%), Positives = 67/135 (49%), Gaps = 11/135 (8%)
Query: 69 LSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVG----NQTSTKITNLK 124
L+ + + V W SP E + I+ Y++++ EDKE K ++G NQTST + L
Sbjct: 626 LTQSQVRVSW-SPAEDHNAPIEKYDIEF---EDKEMAPEKWYSLGKVPGNQTSTTL-KLS 680
Query: 125 GSVLYHLAVKAYNSAGTG-PSSATVNVTTRKPPPSQPPGNIIWNSSD-SKIILNWDQVKA 182
V Y V A N G G PS + V T + P + P ++ ++ + +++ W ++
Sbjct: 681 PYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRW 740
Query: 183 LDNESEVKGYKVLYR 197
+D + Y+V +R
Sbjct: 741 MDWNAPQVQYRVQWR 755
Score = 42.4 bits (98), Expect = 5e-04
Identities = 36/156 (23%), Positives = 65/156 (41%), Gaps = 5/156 (3%)
Query: 23 VHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPL 82
+ P+S + ++V FN +G GP S T +S E P ++ S T + + W PL
Sbjct: 885 LRPYSSYHLEVQAFNGRGSGPASEFT--FSTPEGVPGHPEALHLECQSNTSLLLRWQPPL 942
Query: 83 EKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTST-KITNLKGSVLYHLAVKAYNSAGT 141
N G + GY + Y ++ + + T +T+L + Y ++A G
Sbjct: 943 SHN-GVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGP 1001
Query: 142 GPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNW 177
G + T S GNI + ++ +++W
Sbjct: 1002 GEAIVREGGTMALSGISD-FGNISATAGENYSVVSW 1036
>gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo
sapiens]
Length = 1257
Score = 81.6 bits (200), Expect = 7e-16
Identities = 50/178 (28%), Positives = 89/178 (50%), Gaps = 10/178 (5%)
Query: 26 FSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWAS-PLEK 84
F P+E+KV N++G+GP T+ YS E+ P P L+++ + V W L +
Sbjct: 781 FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQ 840
Query: 85 NRGRIQGYEVKYWRHEDKEENARK------IRTVGNQTSTKITNLKGSVLYHLAVKAYNS 138
+G ++GY V YWR + +++++ + N TS ++ L+ YHL V+A+N
Sbjct: 841 VKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNG 900
Query: 139 AGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLY 196
G+GP+S +T + P P + S++ ++L W L + + GY + Y
Sbjct: 901 RGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQ--PPLSHNGVLTGYVLSY 955
Score = 47.8 bits (112), Expect = 1e-05
Identities = 38/135 (28%), Positives = 67/135 (49%), Gaps = 11/135 (8%)
Query: 69 LSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVG----NQTSTKITNLK 124
L+ + + V W SP E + I+ Y++++ EDKE K ++G NQTST + L
Sbjct: 626 LTQSQVRVSW-SPAEDHNAPIEKYDIEF---EDKEMAPEKWYSLGKVPGNQTSTTL-KLS 680
Query: 125 GSVLYHLAVKAYNSAGTG-PSSATVNVTTRKPPPSQPPGNIIWNSSD-SKIILNWDQVKA 182
V Y V A N G G PS + V T + P + P ++ ++ + +++ W ++
Sbjct: 681 PYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRW 740
Query: 183 LDNESEVKGYKVLYR 197
+D + Y+V +R
Sbjct: 741 MDWNAPQVQYRVQWR 755
Score = 42.4 bits (98), Expect = 5e-04
Identities = 36/156 (23%), Positives = 65/156 (41%), Gaps = 5/156 (3%)
Query: 23 VHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPL 82
+ P+S + ++V FN +G GP S T +S E P ++ S T + + W PL
Sbjct: 885 LRPYSSYHLEVQAFNGRGSGPASEFT--FSTPEGVPGHPEALHLECQSNTSLLLRWQPPL 942
Query: 83 EKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTST-KITNLKGSVLYHLAVKAYNSAGT 141
N G + GY + Y ++ + + T +T+L + Y ++A G
Sbjct: 943 SHN-GVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGP 1001
Query: 142 GPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNW 177
G + T S GNI + ++ +++W
Sbjct: 1002 GEAIVREGGTMALSGISD-FGNISATAGENYSVVSW 1036
>gi|27894376 cell adhesion molecule with homology to L1CAM precursor
[Homo sapiens]
Length = 1224
Score = 80.9 bits (198), Expect = 1e-15
Identities = 52/181 (28%), Positives = 85/181 (46%), Gaps = 13/181 (7%)
Query: 26 FSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWAS-PLEK 84
++P++VKV N G GP + +YS E+ P P +++T ++V W++ P ++
Sbjct: 794 YAPYDVKVQAINQLGSGPDPQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTWSTVPKDR 853
Query: 85 NRGRIQGYEVKYW--------RHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAY 136
GR++GY++ +W R KE N +R G + S + +L +HL V AY
Sbjct: 854 VHGRLKGYQINWWKTKSLLDGRTHPKEVNI--LRFSGQRNSGMVPSLDAFSEFHLTVLAY 911
Query: 137 NSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLY 196
NS G GP S T + P QP + L+W K L+ + GY + Y
Sbjct: 912 NSKGAGPESEPYIFQTPEGVPEQPTFLKVIKVDKDTATLSWGLPKKLN--GNLTGYLLQY 969
Query: 197 R 197
+
Sbjct: 970 Q 970
Score = 42.7 bits (99), Expect = 4e-04
Identities = 40/192 (20%), Positives = 79/192 (41%), Gaps = 9/192 (4%)
Query: 60 PPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTK 119
PP ++ + + W + + N I Y V++ ++++ ++ V + +T
Sbjct: 630 PPENLHLSERQNRSVRLTWEAGADHN-SNISEYIVEFEGNKEEPGRWEELTRVQGKKTTV 688
Query: 120 ITNLKGSVLYHLAVKAYNSAGTG-PSSATVNVTTRKPPPSQPPGNIIWNSSDSK-IILNW 177
I L V Y V A N G PS + + T P + P NI +S K +I+ W
Sbjct: 689 ILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMIIKW 748
Query: 178 DQVKALDNESEVKGYKVLYRWNRQSSTSVIE----TNKTSVELSLPFDEDYIIEIKPFSD 233
+ +K+++ Y+V W Q + E TN T ++ Y ++++ +
Sbjct: 749 EPLKSMEQNGPGLEYRV--TWKPQGAPVEWEEETVTNHTLRVMTPAVYAPYDVKVQAINQ 806
Query: 234 GGDGSSSEQIRI 245
G G + + +
Sbjct: 807 LGSGPDPQSVTL 818
Score = 40.4 bits (93), Expect = 0.002
Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 7/125 (5%)
Query: 22 SVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASP 81
S+ FS F + V +N+KG GP S + + E P + P + + + W P
Sbjct: 897 SLDAFSEFHLTVLAYNSKGAGPESEPYIFQTPEGVP-EQPTFLKVIKVDKDTATLSWGLP 955
Query: 82 LEKNRGRIQGYEVKYW----RHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYN 137
+K G + GY ++Y +E E N I T ++ S ++NL + Y ++A
Sbjct: 956 -KKLNGNLTGYLLQYQIINDTYEIGELNDINI-TTPSKPSWHLSNLNATTKYKFYLRACT 1013
Query: 138 SAGTG 142
S G G
Sbjct: 1014 SQGCG 1018
>gi|81158224 neuronal cell adhesion molecule isoform B precursor [Homo
sapiens]
Length = 1183
Score = 75.1 bits (183), Expect = 6e-14
Identities = 70/266 (26%), Positives = 105/266 (39%), Gaps = 26/266 (9%)
Query: 6 TVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIF 65
T + A+ S+Y+ F P+ +KV N+ G P + +S E+ P P ++
Sbjct: 780 TSVVVANVSKYIVSGTPT--FVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVR 837
Query: 66 ARSLSATDIEVFWAS-PLEKNRGRIQGYEVKYWRHEDKEENAR-----KIRTV-GNQTST 118
+++T EV W PL+ RG +QGY + YW+ + + R KI T G++T
Sbjct: 838 VNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHG 897
Query: 119 KITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWD 178
+ L+ Y L V+ N G GP+S T + PS P I N + + L WD
Sbjct: 898 MLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWD 957
Query: 179 QVKALDNESEVKGYKVLYRWNRQSSTSV----------IETNKTSVEL-SLPFDEDYIIE 227
S G Y Q S I NKT L +L F Y
Sbjct: 958 P------PSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFY 1011
Query: 228 IKPFSDGGDGSSSEQIRIPKISNAYA 253
+ G GS + + + A A
Sbjct: 1012 FYAQTSAGSGSQITEEAVTTVDEAMA 1037
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,040,921
Number of Sequences: 37866
Number of extensions: 503266
Number of successful extensions: 2461
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 79
Number of HSP's that attempted gapping in prelim test: 1456
Number of HSP's gapped (non-prelim): 748
length of query: 282
length of database: 18,247,518
effective HSP length: 101
effective length of query: 181
effective length of database: 14,423,052
effective search space: 2610572412
effective search space used: 2610572412
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.