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Search of human proteins with 28373117
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens]
(1018 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens] 2088 0.0
gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens] 2053 0.0
gi|4827022 contactin 2 precursor [Homo sapiens] 985 0.0
gi|28373129 contactin 5 isoform short [Homo sapiens] 895 0.0
gi|7657359 contactin 5 isoform long [Homo sapiens] 894 0.0
gi|75709184 contactin 3 [Homo sapiens] 876 0.0
gi|28373122 contactin 4 isoform a precursor [Homo sapiens] 874 0.0
gi|7657361 contactin 6 [Homo sapiens] 821 0.0
gi|28373126 contactin 4 isoform c precursor [Homo sapiens] 617 e-176
gi|237858679 neurofascin isoform 3 precursor [Homo sapiens] 365 e-100
gi|89903008 neurofascin isoform 4 precursor [Homo sapiens] 365 e-100
gi|237858677 neurofascin isoform 2 precursor [Homo sapiens] 357 4e-98
gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo ... 345 1e-94
gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo s... 345 1e-94
gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo... 344 3e-94
gi|27894376 cell adhesion molecule with homology to L1CAM precur... 344 3e-94
gi|237858675 neurofascin isoform 1 precursor [Homo sapiens] 337 3e-92
gi|81158224 neuronal cell adhesion molecule isoform B precursor ... 312 9e-85
gi|81158226 neuronal cell adhesion molecule isoform A precursor ... 308 2e-83
gi|119220552 sidekick 1 [Homo sapiens] 281 3e-75
gi|222352127 sidekick 2 [Homo sapiens] 245 2e-64
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 225 1e-58
gi|237858682 neurofascin isoform 6 precursor [Homo sapiens] 219 8e-57
gi|237858680 neurofascin isoform 5 precursor [Homo sapiens] 219 8e-57
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 201 2e-51
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 201 2e-51
gi|28373124 contactin 4 isoform b precursor [Homo sapiens] 198 2e-50
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa... 197 3e-50
gi|157311649 neogenin homolog 1 [Homo sapiens] 191 4e-48
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 184 5e-46
>gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens]
Length = 1018
Score = 2088 bits (5411), Expect = 0.0
Identities = 1018/1018 (100%), Positives = 1018/1018 (100%)
Query: 1 MKMWLLVSHLVIISITTCLAEFTWYRRYGHGVSEEDKGFGPIFEEQPINTIYPEESLEGK 60
MKMWLLVSHLVIISITTCLAEFTWYRRYGHGVSEEDKGFGPIFEEQPINTIYPEESLEGK
Sbjct: 1 MKMWLLVSHLVIISITTCLAEFTWYRRYGHGVSEEDKGFGPIFEEQPINTIYPEESLEGK 60
Query: 61 VSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLASNNY 120
VSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLASNNY
Sbjct: 61 VSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLASNNY 120
Query: 121 GMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVF 180
GMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVF
Sbjct: 121 GMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVF 180
Query: 181 ITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPY 240
ITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPY
Sbjct: 181 ITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPY 240
Query: 241 PADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNI 300
PADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNI
Sbjct: 241 PADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNI 300
Query: 301 QLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIP 360
QLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIP
Sbjct: 301 QLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIP 360
Query: 361 TIRWLKNGYAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPM 420
TIRWLKNGYAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPM
Sbjct: 361 TIRWLKNGYAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPM 420
Query: 421 KKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGG 480
KKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGG
Sbjct: 421 KKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGG 480
Query: 481 IYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVW 540
IYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVW
Sbjct: 481 IYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVW 540
Query: 541 SFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVV 600
SFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVV
Sbjct: 541 SFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVV 600
Query: 601 RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIE 660
RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIE
Sbjct: 601 RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIE 660
Query: 661 GNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRN 720
GNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRN
Sbjct: 661 GNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRN 720
Query: 721 RELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAF 780
RELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAF
Sbjct: 721 RELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAF 780
Query: 781 QVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIVESY 840
QVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIVESY
Sbjct: 781 QVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIVESY 840
Query: 841 QIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFT 900
QIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFT
Sbjct: 841 QIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFT 900
Query: 901 KKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQHDGKLYSTHKH 960
KKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQHDGKLYSTHKH
Sbjct: 901 KKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQHDGKLYSTHKH 960
Query: 961 SIEVPIPRDGEYVVEVRAHSDGGDGVVSQVKISGAPTLSPSLLGLLLPAFGILVYLEF 1018
SIEVPIPRDGEYVVEVRAHSDGGDGVVSQVKISGAPTLSPSLLGLLLPAFGILVYLEF
Sbjct: 961 SIEVPIPRDGEYVVEVRAHSDGGDGVVSQVKISGAPTLSPSLLGLLLPAFGILVYLEF 1018
>gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens]
Length = 1007
Score = 2053 bits (5318), Expect = 0.0
Identities = 1007/1018 (98%), Positives = 1007/1018 (98%), Gaps = 11/1018 (1%)
Query: 1 MKMWLLVSHLVIISITTCLAEFTWYRRYGHGVSEEDKGFGPIFEEQPINTIYPEESLEGK 60
MKMWLLVSHLVIISITTCLA VSEEDKGFGPIFEEQPINTIYPEESLEGK
Sbjct: 1 MKMWLLVSHLVIISITTCLA-----------VSEEDKGFGPIFEEQPINTIYPEESLEGK 49
Query: 61 VSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLASNNY 120
VSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLASNNY
Sbjct: 50 VSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLASNNY 109
Query: 121 GMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVF 180
GMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVF
Sbjct: 110 GMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVF 169
Query: 181 ITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPY 240
ITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPY
Sbjct: 170 ITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPY 229
Query: 241 PADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNI 300
PADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNI
Sbjct: 230 PADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNI 289
Query: 301 QLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIP 360
QLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIP
Sbjct: 290 QLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIP 349
Query: 361 TIRWLKNGYAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPM 420
TIRWLKNGYAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPM
Sbjct: 350 TIRWLKNGYAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPM 409
Query: 421 KKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGG 480
KKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGG
Sbjct: 410 KKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGG 469
Query: 481 IYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVW 540
IYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVW
Sbjct: 470 IYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVW 529
Query: 541 SFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVV 600
SFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVV
Sbjct: 530 SFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVV 589
Query: 601 RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIE 660
RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIE
Sbjct: 590 RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIE 649
Query: 661 GNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRN 720
GNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRN
Sbjct: 650 GNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRN 709
Query: 721 RELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAF 780
RELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAF
Sbjct: 710 RELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAF 769
Query: 781 QVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIVESY 840
QVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIVESY
Sbjct: 770 QVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIVESY 829
Query: 841 QIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFT 900
QIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFT
Sbjct: 830 QIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFT 889
Query: 901 KKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQHDGKLYSTHKH 960
KKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQHDGKLYSTHKH
Sbjct: 890 KKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQHDGKLYSTHKH 949
Query: 961 SIEVPIPRDGEYVVEVRAHSDGGDGVVSQVKISGAPTLSPSLLGLLLPAFGILVYLEF 1018
SIEVPIPRDGEYVVEVRAHSDGGDGVVSQVKISGAPTLSPSLLGLLLPAFGILVYLEF
Sbjct: 950 SIEVPIPRDGEYVVEVRAHSDGGDGVVSQVKISGAPTLSPSLLGLLLPAFGILVYLEF 1007
>gi|4827022 contactin 2 precursor [Homo sapiens]
Length = 1040
Score = 985 bits (2547), Expect = 0.0
Identities = 507/1003 (50%), Positives = 672/1003 (66%), Gaps = 31/1003 (3%)
Query: 9 HLVIISITTCLAEFTWYRRYGHGVSEEDKGFGPIFEEQPINTIYPEESLEGKVSLNCRAR 68
HL++++ ++ W G + FGP+FE+QP++ ++PEES E +V L CRAR
Sbjct: 10 HLLLVAAVALVSSSAWSSALGSQTT-----FGPVFEDQPLSVLFPEESTEEQVLLACRAR 64
Query: 69 ASPFPVYKWRMNNGDVDLT-SDRYSMVGGNLVINNPDKQKDAGIYYCLASNNYGMVRSTE 127
ASP Y+W+MN ++ L R+ +VGGNLVI NP K +DAG+Y CLASN G V S E
Sbjct: 65 ASPPATYRWKMNGTEMKLEPGSRHQLVGGNLVIMNPTKAQDAGVYQCLASNPVGTVVSRE 124
Query: 128 ATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRR 187
A L FG+L F EER V+ EG G++L C+PP H+P LSYRWLLNEFP FI D R
Sbjct: 125 AILRFGFLQEFSKEERDPVKAHEGWGVMLPCNPPAHYPG-LSYRWLLNEFPNFIPTDGRH 183
Query: 188 FVSQTNGNLYIANVEASDKGNYSCFVSSPS--ITKSVFSKFIPLIPIPERTTKPYPADIV 245
FVSQT GNLYIA ASD GNYSC +S TKSVFSKF L + T+ + I
Sbjct: 184 FVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQL-NLAAEDTRLFAPSIK 242
Query: 246 VQFK-DVYALMGQNVTLECFALGNPVPDIRWRKV---LEPMPSTAEISTSGAVLKIFNIQ 301
+F + YAL+GQ VTLECFA GNPVP I+WRKV L P +TAE L+I ++
Sbjct: 243 ARFPAETYALVGQQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTAE-----PTLQIPSVS 297
Query: 302 LEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPT 361
EDEG YECEAEN +G+D Q RI VQA PEW++ I+DTE DIGS+L W C A GKP PT
Sbjct: 298 FEDEGTYECEAENSKGRDTVQGRIIVQAQPEWLKVISDTEADIGSNLRWGCAAAGKPRPT 357
Query: 362 IRWLKNGYAYHK--------GELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAP 413
+RWL+NG G+LR ++ E++GMYQC+AEN +G IYA+AEL + ALAP
Sbjct: 358 VRWLRNGEPLASQNRVEVLAGDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAP 417
Query: 414 TFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINN 473
F +NP+++ I AA+GG ++I C+P+AAPK WSKGTE LVNSSR+ + DG+L I N
Sbjct: 418 DFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRN 477
Query: 474 ITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPA 533
I+R+D G YTCFAEN GKANSTG L + D T+I LAP +ADI +G+N T+QC AS DP
Sbjct: 478 ISRSDEGKYTCFAENFMGKANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPT 537
Query: 534 LDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSS 593
+DLTF W+ + + IDF+K HY+R + ++ G+L I NAQL+H G+YTC AQT+VD++S
Sbjct: 538 MDLTFTWTLDDFPIDFDKPGGHYRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSAS 597
Query: 594 ASADLVVRGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAK 653
A ++VRGPPGPPGG+ + DI T++ L+WSRG DNHSPI+KYT+Q +T + WK +
Sbjct: 598 KEATVLVRGPPGPPGGVVVRDIGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAGKWKQVR 657
Query: 654 TDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDV 713
T+P IEGN E A+ + L PWM+YEFRV+A+N LG GEPS PS++I+T AAP+VAPS +
Sbjct: 658 TNPANIEGNAETAQVLGLTPWMDYEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGL 717
Query: 714 GGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDET 773
GGGG EL + W P+SREY G+ FGY+++F+ W+ V D +V+ +E+
Sbjct: 718 SGGGGAPGELIVNWTPMSREYQNGDGFGYLLSFRRQGSTHWQTARVPGADAQYFVYSNES 777
Query: 774 MSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHV- 832
+ P T F+VK++++N +GDGP SL A++ SA++ P APT+V K +SSSE++V WE V
Sbjct: 778 VRPYTPFEVKIRSYNRRGDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQ 837
Query: 833 --LEKIVESYQIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCG 890
+ I+ Y+IRYW A DKE AA+RV+ + SAR+ L P+T+Y + V A N AG G
Sbjct: 838 QDMNGILLGYEIRYWKAGDKEAAADRVRTAGLDTSARVSGLHPNTKYHVTVRAYNRAGTG 897
Query: 891 PPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQH 950
P S A T K PP +PP IS S S I WD VV NES VTGYK+LY+ D
Sbjct: 898 PASPSANATTMKPPPRRPPGNISWTFSSSSLSIKWDPVVPFRNESAVTGYKMLYQNDLHL 957
Query: 951 DGKLYSTHKHSIEVPIPRD-GEYVVEVRAHSDGGDGVVSQVKI 992
L+ T K+ IE+P+P D G +V++R GGDG+ ++V I
Sbjct: 958 TPTLHLTGKNWIEIPVPEDIGHALVQIRTTGPGGDGIPAEVHI 1000
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 895 bits (2313), Expect = 0.0
Identities = 457/996 (45%), Positives = 618/996 (62%), Gaps = 28/996 (2%)
Query: 10 LVIISITTCLAEFTWYRRYGHGVSEEDKGFGPIFEEQPINTIYPEESLEGKVSLNCRARA 69
++ +S+T CL+E Y GP+F ++P + I+P +S E KV+LNC R
Sbjct: 8 MLFLSVTMCLSESVDY--------------GPVFVQEPDDIIFPTDSDEKKVALNCEVRG 53
Query: 70 SPFPVYKWRMNNGDVDLTSD-RYSMVGGNLVINNPDKQKDAGIYYCLASNNYGMVRSTEA 128
+P P Y+W N ++DL SD RYS++ G +I+NP + KD+G Y CLA+N G + S EA
Sbjct: 54 NPVPSYRWLRNGTEIDLESDYRYSLIDGTFIISNPSEAKDSGHYQCLATNTVGSILSREA 113
Query: 129 TLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRF 188
TL F YL F R V V+EG+G+VL+C PP H P+ + Y W+ NEFP F+ D RRF
Sbjct: 114 TLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPPHSPE-IIYSWVFNEFPSFVAEDSRRF 172
Query: 189 VSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQF 248
+SQ GNLYI+ V+ SD G+Y C V + V S PL + Y I V F
Sbjct: 173 ISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHF 232
Query: 249 K-DVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNIQLEDEGI 307
V A G V +ECFALGNPVP I W KV +PS A + S AVL+I N+QL+D GI
Sbjct: 233 PFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQAVLEIPNVQLDDAGI 292
Query: 308 YECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKN 367
YEC AEN RGK+ + ++ V +P WVE +NDT++D GS L W C ATGKP PT RWLKN
Sbjct: 293 YECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKN 352
Query: 368 GYAYH--------KGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNP 419
G G L +++V +AGMYQC+AEN YGAIYA+AELKILA APTF +N
Sbjct: 353 GVPLSPQSRVEMVNGVLMIHNVNQSDAGMYQCLAENKYGAIYASAELKILASAPTFALNQ 412
Query: 420 MKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDG 479
+KK I+ K V+IECKP+ +PKP SW KG + + RI I DGSL I N +++D
Sbjct: 413 LKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKSDE 472
Query: 480 GIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFV 539
G Y C EN G A +L + +PTRI L P ++TVGE+ + C A D +LD+TF
Sbjct: 473 GKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFY 532
Query: 540 WSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLV 599
W+ G IDF +E H++ S+ +L+IRN L HAGRY C QT D+ S A+L+
Sbjct: 533 WTLKGQPIDFEEEGGHFESIRAQASSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELL 592
Query: 600 VRGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPII 659
VRGPPGPPG + +E+I ++ L+WS +DNHSPIS Y +Q ++ S W+ KT P II
Sbjct: 593 VRGPPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEII 652
Query: 660 EGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGR 719
G+ME+A AVDL PW+EYEFRVVATN +G G+PS PS I+T+ A P AP++V G GR
Sbjct: 653 TGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGR 712
Query: 720 NRELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTA 779
EL I W P+S E+ G FGYIVAF+P WK+ VT+ + +++++DE++ P T
Sbjct: 713 RHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTP 772
Query: 780 FQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKI--V 837
F+VKV +NNKGDGP+S + VI SA+ PS APT+V +S SEI V W+H+ E +
Sbjct: 773 FEVKVGVYNNKGDGPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIKESLGRP 832
Query: 838 ESYQIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIE 897
+ +++ YW ++E+ A V+ E L L +T Y V A N AG GPPS +
Sbjct: 833 QGFEVGYWKDMEQEDTAETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVS 892
Query: 898 AFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQHDGKLYST 957
A TKK+PPSQ P + + GS+ + W+ V+ L+NES V GYKV YR +G + ++ T
Sbjct: 893 ATTKKSPPSQAPSNLRWEQQGSQVSLGWEPVIPLANESEVVGYKVFYRQEGHSNSQVIET 952
Query: 958 HKHSIEVPIPRDGEYVVEVRAHSDGGDGVV-SQVKI 992
K VP+P G Y++EVRA+S+GGDG SQ+++
Sbjct: 953 QKLQAVVPLPDAGVYIIEVRAYSEGGDGTASSQIRV 988
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 894 bits (2309), Expect = 0.0
Identities = 452/972 (46%), Positives = 610/972 (62%), Gaps = 14/972 (1%)
Query: 34 EEDKGFGPIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSD-RYS 92
+E +GP+F ++P + I+P +S E KV+LNC R +P P Y+W N ++DL SD RYS
Sbjct: 92 DESVDYGPVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYS 151
Query: 93 MVGGNLVINNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGK 152
++ G +I+NP + KD+G Y CLA+N G + S EATL F YL F R V V+EG+
Sbjct: 152 LIDGTFIISNPSEAKDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQ 211
Query: 153 GMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCF 212
G+VL+C PP H P+ + Y W+ NEFP F+ D RRF+SQ GNLYI+ V+ SD G+Y C
Sbjct: 212 GVVLMCSPPPHSPE-IIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICL 270
Query: 213 VSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFK-DVYALMGQNVTLECFALGNPVP 271
V + V S PL + Y I V F V A G V +ECFALGNPVP
Sbjct: 271 VKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVP 330
Query: 272 DIRWRKVLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFP 331
I W KV +PS A + S AVL+I N+QL+D GIYEC AEN RGK+ + ++ V +P
Sbjct: 331 TITWMKVNGYIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYP 390
Query: 332 EWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYH--------KGELRLYDVTF 383
WVE +NDT++D GS L W C ATGKP PT RWLKNG G L +++V
Sbjct: 391 HWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVNGVLMIHNVNQ 450
Query: 384 ENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPK 443
+AGMYQC+AEN YGAIYA+AELKILA APTF +N +KK I+ K V+IECKP+ +PK
Sbjct: 451 SDAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPK 510
Query: 444 PKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITD 503
P SW KG + + RI I DGSL I N +++D G Y C EN G A +L + +
Sbjct: 511 PTISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE 570
Query: 504 PTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLD 563
PTRI L P ++TVGE+ + C A D +LD+TF W+ G IDF +E H++
Sbjct: 571 PTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQA 630
Query: 564 SNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALT 623
S+ +L+IRN L HAGRY C QT D+ S A+L+VRGPPGPPG + +E+I ++ L+
Sbjct: 631 SSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEITESTATLS 690
Query: 624 WSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVA 683
WS +DNHSPIS Y +Q ++ S W+ KT P II G+ME+A AVDL PW+EYEFRVVA
Sbjct: 691 WSPAADNHSPISSYNLQARSPFSLGWQTVKTVPEIITGDMESAMAVDLNPWVEYEFRVVA 750
Query: 684 TNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYI 743
TN +G G+PS PS I+T+ A P AP++V G GR EL I W P+S E+ G FGYI
Sbjct: 751 TNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFGYI 810
Query: 744 VAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINS 803
VAF+P WK+ VT+ + +++++DE++ P T F+VKV +NNKGDGP+S + VI S
Sbjct: 811 VAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSQIVVICS 870
Query: 804 AQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKI--VESYQIRYWAAHDKEEAANRVQVTS 861
A+ PS APT+V +S SEI V W+H+ E + + +++ YW ++E+ A V+
Sbjct: 871 AEGEPSAAPTDVKATSVSVSEILVAWKHIKESLGRPQGFEVGYWKDMEQEDTAETVKTRG 930
Query: 862 QEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRY 921
E L L +T Y V A N AG GPPS + A TKK+PPSQ P + + GS+
Sbjct: 931 NESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPPSQAPSNLRWEQQGSQV 990
Query: 922 IITWDHVVALSNESTVTGYKVLYRPDGQHDGKLYSTHKHSIEVPIPRDGEYVVEVRAHSD 981
+ W+ V+ L+NES V GYKV YR +G + ++ T K VP+P G Y++EVRA+S+
Sbjct: 991 SLGWEPVIPLANESEVVGYKVFYRQEGHSNSQVIETQKLQAVVPLPDAGVYIIEVRAYSE 1050
Query: 982 GGDGVV-SQVKI 992
GGDG SQ+++
Sbjct: 1051 GGDGTASSQIRV 1062
>gi|75709184 contactin 3 [Homo sapiens]
Length = 1028
Score = 876 bits (2264), Expect = 0.0
Identities = 434/965 (44%), Positives = 612/965 (63%), Gaps = 17/965 (1%)
Query: 40 GPIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSD-RYSMVGGNL 98
GP+F ++P N+I+P S + K++L+C AR +P P Y+W++N D+D++ + RY + GGNL
Sbjct: 25 GPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDIDMSMEHRYKLNGGNL 84
Query: 99 VINNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLC 158
V+ NP++ D G Y C A+N+ G + S EA L F YL+ F + R V V+EG+G+VLLC
Sbjct: 85 VVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLC 144
Query: 159 DPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSI 218
PP H +LSY W+ NE+P F+ D RRFVSQ G+LYI+ VE SD GNY+C V+S
Sbjct: 145 GPPPH-SGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCVVTSMVT 203
Query: 219 TKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVY-ALMGQNVTLECFALGNPVPDIRWRK 277
V PL+ + Y I VQF + A G V LECFALGNP+P I WR+
Sbjct: 204 NARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRR 263
Query: 278 VLE-PMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEH 336
P S ++ VL+I N Q ED G YEC AEN RGK+ + R+ A P WV+
Sbjct: 264 SDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQL 323
Query: 337 INDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAY--------HKGELRLYDVTFENAGM 388
I D E+ + LYW C A+GKP P+ RWLKNG A G L + +++ ++GM
Sbjct: 324 IKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQIENGALTISNLSVTDSGM 383
Query: 389 YQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSW 448
+QCIAEN +G +Y++AELK++A AP F NPMKK + G V ++CKP+A+P+ SW
Sbjct: 384 FQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSW 443
Query: 449 SKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRII 508
KG + RI + DG L+I N+T+ D G YTC AEN GKAN T LV+T+PTRI
Sbjct: 444 KKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRIT 503
Query: 509 LAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGEL 568
LAP N D++VGE+ + C DP LD+ F W FNG + DF K+ H+++ S+G+L
Sbjct: 504 LAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEK-VGGSSSGDL 562
Query: 569 LIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALTWSRGS 628
+IRN QLKH+G+Y C QT VD+ S++ADL+VRG PGPP +++++I T+ L+W G
Sbjct: 563 MIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGK 622
Query: 629 DNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLG 688
DNHSP+ Y+IQ +T S W+ T P +I+G A V+L PW+EYEFRVVA+N +G
Sbjct: 623 DNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIG 682
Query: 689 RGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKP 748
GEPS+PS +++T+ A P V PS+V GGGG EL ITW P+ E G FGY+VAF+P
Sbjct: 683 GGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRP 742
Query: 749 FDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAP 808
W + VT+PDT RYV ++E++ P + ++VKV +NNKG+GP+S V + SA++ P
Sbjct: 743 LGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEP 802
Query: 809 SEAPTEVGVKVLSSSEISVHWEHVLEKI----VESYQIRYWAAHDKEEAANRVQVTSQEY 864
+ AP++V LSSSEI V W + K+ + Y++RYW KEE++++++V E
Sbjct: 803 TVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGNET 862
Query: 865 SARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIIT 924
SARL L + Y+ V A NSAG GP S + TKK PPSQPP + + ++ ++
Sbjct: 863 SARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLN 922
Query: 925 WDHVVALSNESTVTGYKVLYRPDGQHDGKLYSTHKHSIEVPIPRDGEYVVEVRAHSDGGD 984
W+ V A+ NES VTGYKV YR Q++ ++ +T+K S E+ +P +Y++EV+A +DGGD
Sbjct: 923 WEQVKAMENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELVLPIKEDYIIEVKATTDGGD 982
Query: 985 GVVSQ 989
G S+
Sbjct: 983 GTSSE 987
Score = 76.3 bits (186), Expect = 1e-13
Identities = 73/285 (25%), Positives = 126/285 (44%), Gaps = 30/285 (10%)
Query: 667 RAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTIT 726
R ++P+ YE +V N G G P P + + P VAPS V + E+ ++
Sbjct: 764 RNESIVPYSPYEVKVGVYNNKGEG-PFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVS 822
Query: 727 WAPLSREYHYGNNFGYIVAFKPFDGEEWK--KVTVTNPDTGRYVHKDETMSPSTAFQVKV 784
W + + G+ GY V + G+E K+ V +T + + + A+ V
Sbjct: 823 WNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGNETSARLRG---LKSNLAYYTAV 879
Query: 785 KAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVL----EKIVESY 840
+A+N+ G GP+S + + + PS+ P V V + +++ ++WE V E V Y
Sbjct: 880 RAYNSAGAGPFSATVNVTTKKTPPSQPPGNV-VWNATDTKVLLNWEQVKAMENESEVTGY 938
Query: 841 QIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQ-YFIEVGACNSAGCGPPSDMIEAF 899
++ Y + + N VQV + ++ E +LP + Y IEV A G G S+ I
Sbjct: 939 KVFY-----RTSSQNNVQVLNTNKTSA-ELVLPIKEDYIIEVKATTDGGDGTSSEQIRI- 991
Query: 900 TKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLY 944
PRI S GS I+ +V +S+ + + ++Y
Sbjct: 992 ---------PRITSMDARGSTSAIS--NVHPMSSYMPIVLFLIVY 1025
>gi|28373122 contactin 4 isoform a precursor [Homo sapiens]
Length = 1026
Score = 874 bits (2257), Expect = 0.0
Identities = 439/964 (45%), Positives = 603/964 (62%), Gaps = 17/964 (1%)
Query: 40 GPIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSD-RYSMVGGNL 98
GPIF ++P ++P +S E KV LNC + +P P +W++N DVD D RYS+V G+L
Sbjct: 25 GPIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSL 84
Query: 99 VINNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLC 158
+INNP+K +DAG Y C A+N++G + S EA L F YLD F R V V+ G+GMVLLC
Sbjct: 85 LINNPNKTQDAGTYQCTATNSFGTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQGMVLLC 144
Query: 159 DPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSI 218
PP H +LSY W+ NE+P + D RRFVSQ GNLYIA VE SD GNY+C V++
Sbjct: 145 GPPPH-SGELSYAWIFNEYPSY--QDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVT 201
Query: 219 TKSVFSKFIPLIPIPERTTKPYPADIVVQFKD-VYALMGQNVTLECFALGNPVPDIRWRK 277
V PLI + Y I VQF + V G V LECFALGNPVP I WR+
Sbjct: 202 NHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWRR 261
Query: 278 VL-EPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEH 336
+P+ A S +L+I N Q ED G+YEC AEN RGK+ + ++ A P W++
Sbjct: 262 ADGKPIARKARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQPNWIQK 321
Query: 337 INDTEVDIGSDLYWPCVATGKPIPTIRWLKNG--------YAYHKGELRLYDVTFENAGM 388
IND V + +++W C A G+P PT +WLKNG +G L + V +AGM
Sbjct: 322 INDIHVAMEENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSDAGM 381
Query: 389 YQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSW 448
YQC+AEN +G I++NAEL ++A+ P F +K+ L GG V+IECKPKA+PKP ++W
Sbjct: 382 YQCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTW 441
Query: 449 SKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRII 508
KG + L + RI I EDG+L I N+T++D G YTC A N+ G A+STG LV+ DPTR++
Sbjct: 442 KKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVM 501
Query: 509 LAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGEL 568
+ P + D+TVGE+ + C + D +LD+ F WSFNG++IDF+++ H++R DS G+L
Sbjct: 502 VPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDL 561
Query: 569 LIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALTWSRGS 628
+IRN QLKHAG+Y C QT VD SA+ADL+VRGPPGPP + I++I T+ L+W G
Sbjct: 562 MIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGP 621
Query: 629 DNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLG 688
DNHSPI+ Y IQ +T S W+ T P +I+G A V L PW+EYEFR VA N +G
Sbjct: 622 DNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIG 681
Query: 689 RGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKP 748
GEPS PS + +T+ A P V P++V GGGG EL ITW + E G FGY+VAF+P
Sbjct: 682 IGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRP 741
Query: 749 FDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAP 808
+ W + + D RYV ++E++ P + F+VKV FNNKG+GP+S V+ SA++ P
Sbjct: 742 YGKMIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEP 801
Query: 809 SEAPTEVGVKVLSSSEISVHWEHVLEK---IVESYQIRYWAAHDKEEAANRVQVTSQEYS 865
++ P + + LS+++I V W LEK ++ Y+++YW DKEE A +++ + S
Sbjct: 802 TKPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTS 861
Query: 866 ARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITW 925
++ NL Y + V A NSAG GP S + T+K PPSQPP I S S+ I+ W
Sbjct: 862 TKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNW 921
Query: 926 DHVVALSNESTVTGYKVLYRPDGQHDGKLYSTHKHSIEVPIPRDGEYVVEVRAHSDGGDG 985
D V AL NES V GYKVLYR + Q + T+K S+E+ +P D +Y++E++ SDGGDG
Sbjct: 922 DQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDG 981
Query: 986 VVSQ 989
S+
Sbjct: 982 SSSE 985
>gi|7657361 contactin 6 [Homo sapiens]
Length = 1028
Score = 821 bits (2120), Expect = 0.0
Identities = 421/985 (42%), Positives = 599/985 (60%), Gaps = 18/985 (1%)
Query: 41 PIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLT-SDRYSMVGGNLV 99
PIF ++P + I+P + + +V LNC A P P Y+W+ N D+D T S Y + GG+L
Sbjct: 26 PIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLA 85
Query: 100 INNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCD 159
IN+P +D G+Y CLA+N G + S +A L F Y++ F + R V V+EG+G+VLLC
Sbjct: 86 INSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCG 145
Query: 160 PPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSIT 219
PP HF DLSY W N+ P+++ D RRFVSQ GNLYIA VE SD GNY+CF+++
Sbjct: 146 PPPHF-GDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEAQ 204
Query: 220 KSVFSKFIPLIPIPERTTKPYPADIVVQFKD-VYALMGQNVTLECFALGNPVPDIRWRKV 278
+SV PL+ + Y I V+F + + A +V LECFALGNPVPDI WR++
Sbjct: 205 RSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRRL 264
Query: 279 L-EPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHI 337
P+P + S S A+L+I N Q EDEG YEC A N+RG++ + ++ A PEW + I
Sbjct: 265 DGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKI 324
Query: 338 NDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYH--------KGELRLYDVTFENAGMY 389
+T + I +L W C A+GKP P WLKNG + G L + + ++G+Y
Sbjct: 325 QNTHLSIYDNLLWECKASGKPNPWYTWLKNGERLNPEERIQIENGTLIITMLNVSDSGVY 384
Query: 390 QCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWS 449
QC AEN Y IYANAEL++LA AP F +P+KKK GG ++I CKP A P+ SW
Sbjct: 385 QCAAENKYQIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWK 444
Query: 450 KGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIIL 509
+GTE L S RI + EDGSL+I NITR+D G YTC A N G A +TG+L++ + T I +
Sbjct: 445 RGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITV 504
Query: 510 APINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELL 569
P D+TVGE+ + C S DP++++ FVW FNG VID K H++R +S G+L+
Sbjct: 505 PPSKMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFER-IGGESVGDLM 563
Query: 570 IRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALTWSRGSD 629
IRN QL H+G+Y CT QT +++ SA AD++VRGPPGPP +++EDI +T+ L+W G D
Sbjct: 564 IRNIQLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPD 623
Query: 630 NHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGR 689
N+SPI +TIQT+T S W+ T P I+ G A V L PW+EYEFRVVA N++G
Sbjct: 624 NNSPIQIFTIQTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGI 683
Query: 690 GEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPF 749
GEPS PS ++T + P VAP ++ GGGG EL ITW + E G FGYI+ F+P
Sbjct: 684 GEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPV 743
Query: 750 DGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPS 809
W K V++ ++ R+V+++E++ P + F+VKV +NN+G+G S V ++ S +D P
Sbjct: 744 GSTTWSKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQ 803
Query: 810 EAPTEVGVKVLSSSEISVHWEHVL----EKIVESYQIRYWAAHDKEEAANRVQVTSQEYS 865
AP ++ S+SE+ V W + V Y++ YW KE +++V+ +
Sbjct: 804 LAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRVSGNVTT 863
Query: 866 ARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITW 925
+ L +T YF V A N+AG GP S + TKK+PPSQPP I+ + S+ + W
Sbjct: 864 KNITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNW 923
Query: 926 DHVVALSNESTVTGYKVLYRPDGQHDGKLYSTHKHSIEVPIPRDGEYVVEVRAHSDGGDG 985
+HV + NES V GYK+LYR + Q + T+ S E+ +P + +Y++E+R SDGGDG
Sbjct: 924 EHVKTMENESEVLGYKILYRQNRQSKTHILETNNTSAELLVPFEEDYLIEIRTVSDGGDG 983
Query: 986 VVS-QVKISGAPTLSPSLLGLLLPA 1009
S +++I +LS + L P+
Sbjct: 984 SSSEEIRIPKMSSLSSRGIQFLEPS 1008
>gi|28373126 contactin 4 isoform c precursor [Homo sapiens]
Length = 698
Score = 617 bits (1590), Expect = e-176
Identities = 296/654 (45%), Positives = 417/654 (63%), Gaps = 11/654 (1%)
Query: 347 DLYWPCVATGKPIPTIRWLKNG--------YAYHKGELRLYDVTFENAGMYQCIAENTYG 398
+++W C A G+P PT +WLKNG +G L + V +AGMYQC+AEN +G
Sbjct: 4 NVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHG 63
Query: 399 AIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNS 458
I++NAEL ++A+ P F +K+ L GG V+IECKPKA+PKP ++W KG + L +
Sbjct: 64 VIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILKEN 123
Query: 459 SRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITV 518
RI I EDG+L I N+T++D G YTC A N+ G A+STG LV+ DPTR+++ P + D+TV
Sbjct: 124 ERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTV 183
Query: 519 GENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHA 578
GE+ + C + D +LD+ F WSFNG++IDF+++ H++R DS G+L+IRN QLKHA
Sbjct: 184 GESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHA 243
Query: 579 GRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYT 638
G+Y C QT VD SA+ADL+VRGPPGPP + I++I T+ L+W G DNHSPI+ Y
Sbjct: 244 GKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYV 303
Query: 639 IQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNR 698
IQ +T S W+ T P +I+G A V L PW+EYEFR VA N +G GEPS PS +
Sbjct: 304 IQARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEK 363
Query: 699 IKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVT 758
+T+ A P V P++V GGGG EL ITW + E G FGY+VAF+P+ W
Sbjct: 364 RRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYGKMIWMLTV 423
Query: 759 VTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVK 818
+ + D RYV ++E++ P + F+VKV FNNKG+GP+S V+ SA++ P++ P + +
Sbjct: 424 LASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFAR 483
Query: 819 VLSSSEISVHWEHVLEK---IVESYQIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDT 875
LS+++I V W LEK ++ Y+++YW DKEE A +++ + S ++ NL
Sbjct: 484 SLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSV 543
Query: 876 QYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNES 935
Y + V A NSAG GP S + T+K PPSQPP I S S+ I+ WD V AL NES
Sbjct: 544 LYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNES 603
Query: 936 TVTGYKVLYRPDGQHDGKLYSTHKHSIEVPIPRDGEYVVEVRAHSDGGDGVVSQ 989
V GYKVLYR + Q + T+K S+E+ +P D +Y++E++ SDGGDG S+
Sbjct: 604 EVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSE 657
Score = 79.0 bits (193), Expect = 2e-14
Identities = 71/275 (25%), Positives = 108/275 (39%), Gaps = 32/275 (11%)
Query: 255 MGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAEN 314
M +NV EC A G P P +W K EP+ + I L I + L D G+Y+C AEN
Sbjct: 1 MEENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAEN 60
Query: 315 IRGKDKHQARIYVQAF-PEWVEHI--NDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAY 371
G A + V A P++ + T V +G ++ C P P W K
Sbjct: 61 KHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDIL 120
Query: 372 HK---------GELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKK 422
+ G LR+ +VT +AG Y CIA N +G A++ ++ PT M P
Sbjct: 121 KENERITISEDGNLRIINVTKSDAGSYTCIATNHFGT--ASSTGNLVVKDPTRVMVPPSS 178
Query: 423 KILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWED-------------GSL 469
+ G +++ C+ ++ W N I D G L
Sbjct: 179 MDVTV-GESIVLPCQVTHDHSLDIVFT----WSFNGHLIDFDRDGDHFERVGGQDSAGDL 233
Query: 470 EINNITRNDGGIYTCFAENNRGKANSTGTLVITDP 504
I NI G Y C + + + ++ L++ P
Sbjct: 234 MIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGP 268
Score = 69.3 bits (168), Expect = 2e-11
Identities = 87/307 (28%), Positives = 126/307 (41%), Gaps = 31/307 (10%)
Query: 57 LEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLA 116
+E V C+A P P YKW + NG+ LT DR + G L I + DAG+Y CLA
Sbjct: 1 MEENVFWECKANGRPKPTYKW-LKNGEPLLTRDRIQIEQGTLNITIVNLS-DAGMYQCLA 58
Query: 117 SNNYGMVRSTEATLSFGYLDP-FPPEERPEVR-VKEGKGMVLLCDPPYHFPDDLSYRWLL 174
N +G++ S A LS + P F V VK G +V+ C P P + Y W
Sbjct: 59 ENKHGVIFSN-AELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKAS-PKPV-YTWKK 115
Query: 175 NEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPE 234
I + R +GNL I NV SD G+Y+C ++ T S + + P
Sbjct: 116 GRD---ILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLV--VKDPT 170
Query: 235 RTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDI----RWRKVLEPMPSTAEI-- 288
R P P+ + V +G+++ L C + DI + L +
Sbjct: 171 RVMVP-PSSMDV-------TVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFE 222
Query: 289 ----STSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEV-D 343
S L I NIQL+ G Y C + + A + V+ P E + E+ D
Sbjct: 223 RVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITD 282
Query: 344 IGSDLYW 350
+ L W
Sbjct: 283 TTAQLSW 289
>gi|237858679 neurofascin isoform 3 precursor [Homo sapiens]
Length = 1174
Score = 365 bits (937), Expect = e-100
Identities = 281/926 (30%), Positives = 412/926 (44%), Gaps = 87/926 (9%)
Query: 61 VSLNCRARASPFPVYKWRMNNGDVDLTSD-RYSMV--GGNLVIN-----NPDKQKDAGIY 112
+ + C A+ +P P + W N+ ++ D R SM G LVI+ P++ + G Y
Sbjct: 53 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYE--GEY 110
Query: 113 YCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRW 172
C A N +G S L +P E V V+EG + L C+PP P + + W
Sbjct: 111 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIF-W 169
Query: 173 LLNEFPVFITMDKRRFVSQ-TNGNLYIANVEASD-KGNYSCFVSSPSITKSVFSKFIPLI 230
+ + IT DKR VSQ NG+LY +NV D + +YSC T ++ K
Sbjct: 170 MSSSMEP-ITQDKR--VSQGHNGDLYFSNVMLQDMQTDYSCNARF-HFTHTIQQK--NPF 223
Query: 231 PIPERTTKPYPADIVVQFKDVYA-----------------------LMGQNVTLECFALG 267
+ T PY + D+Y+ L G ++ LEC A G
Sbjct: 224 TLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASG 283
Query: 268 NPVPDIRWRKVLEPMPS-TAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIY 326
P PDI W K +PS A+ L+I N+ ED G Y C A N G +H +
Sbjct: 284 VPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVR 343
Query: 327 VQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHK----------GEL 376
V+A P W++ + + G D C A G P PT++W+ NG G+
Sbjct: 344 VKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT 403
Query: 377 RLY-DVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIE 435
++ D + +YQC N +G + ANA + +L + P ++P + I R ++
Sbjct: 404 IIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRM-LSPRNQLIRVILYNRTRLD 462
Query: 436 CKPKAAPKPKFSWSK-GTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKAN 494
C +P P W K G ++ ++E+GSLEI I + D GIYTC A N GKA
Sbjct: 463 CPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAE 522
Query: 495 STGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENI 554
+ L + DPTRI P + G ++C DP+L LT W +
Sbjct: 523 NQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW--------LKDDEP 574
Query: 555 HYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIED 614
Y N M + L I + G YTC A T +D A A L V G P P L + D
Sbjct: 575 LYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGRPDRPRDLELTD 634
Query: 615 IRATSVALTWSRGSDNHSPISKYTIQTK--TILSDDWKDAKTDPPIIEGNMEAARAVDLI 672
+ SV LTW G N+SPI+ Y +Q + W D P G++ +A + L
Sbjct: 635 LAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYP----GSVNSA-VLRLS 689
Query: 673 PWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSR 732
P++ Y+FRV+A N +G PS+PS R +T GA P P DV G G R + ITW P++
Sbjct: 690 PYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNA 749
Query: 733 EYHYGNNFGYIVAFKPFDGEE-WKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKG 791
+G N YIV ++ + E W VTV RYV + ++++V+A N+ G
Sbjct: 750 TSAFGPNLRYIVKWRRRETREAWNNVTVWG---SRYVVGQTPV--YVPYEIRVQAENDFG 804
Query: 792 DGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIVESYQIRYWAAHDKE 851
GP + S +D P APTEV V+V++S+ IS+ W V V+ Y A + +E
Sbjct: 805 KGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRE 864
Query: 852 EAANRVQVTSQEYSAR----------LENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTK 901
+ + SQ+ + L P + Y +E+ N G GP S+ E T
Sbjct: 865 SSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTP 924
Query: 902 KAPPSQPPRIISSVRSGSRYIITWDH 927
+ PS P R + + WDH
Sbjct: 925 EGVPSAPRRFRVRQPNLETINLEWDH 950
Score = 68.2 bits (165), Expect = 4e-11
Identities = 92/403 (22%), Positives = 143/403 (35%), Gaps = 57/403 (14%)
Query: 230 IPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK-----VLEPMPS 284
I IP T+P P KD N+ +EC A GNP P W + + P
Sbjct: 25 IEIPMDLTQP-PTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPR 83
Query: 285 TAEISTSGAVLKIFNI---QLEDEGIYECEAENIRGKD-KHQARIYVQAFPEW-VEHIND 339
+ SG ++ F E EG Y+C A N G ++ R+ V P W E+++
Sbjct: 84 VSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP 143
Query: 340 TEVDIGSDLYWPC-VATGKPIPTIRWL----------KNGYAYHKGELRLYDVTFENAGM 388
V G+ L C G P P I W+ K H G+L +V ++
Sbjct: 144 VVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQT 203
Query: 389 -YQCIAENTYGAIYANAE---LKILALAP-----------------TFEMNP-------M 420
Y C A + LK+L P E P
Sbjct: 204 DYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGT 263
Query: 421 KKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGG 480
+ +G +++EC P P +W K L + + +L I N++ D G
Sbjct: 264 ASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSG 323
Query: 481 IYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVW 540
Y C A N G T ++ + + P N + GE+ + C A+ +P T W
Sbjct: 324 EYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNP--KPTVQW 381
Query: 541 SFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTC 583
NG + N + + + ++ R+ Q+ Y C
Sbjct: 382 MVNGEPLQSAPPNPNRE-----VAGDTIIFRDTQISSRAVYQC 419
Score = 53.9 bits (128), Expect = 7e-07
Identities = 43/180 (23%), Positives = 80/180 (44%), Gaps = 9/180 (5%)
Query: 57 LEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLA 116
L + L+C SP P +W N +L Y + + +++D GIY C+A
Sbjct: 455 LYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVA 514
Query: 117 SNNYGMVRSTEATLSFGYLDPFPPEERPEVRV-KEGKGMVLLCDPPYHFPDDLSYRWLLN 175
+N G E + DP PE +V + G + L C + L+ WL +
Sbjct: 515 TNILG---KAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 571
Query: 176 EFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPER 235
+ P++I + + + +L I V D+G+Y+C V+S + + + ++ ++ P+R
Sbjct: 572 DEPLYI----GNRMKKEDDSLTIFGVAERDQGSYTC-VASTELDQDLAKAYLTVLGRPDR 626
Score = 36.6 bits (83), Expect = 0.12
Identities = 42/214 (19%), Positives = 77/214 (35%), Gaps = 13/214 (6%)
Query: 603 PPGPPGGLRIEDIRATSVALTWSRGSDNH-----SPISKYTIQTKTILSDDWKDAKTDPP 657
P P +++ + +T+++L W+R + Y + ++L + W K
Sbjct: 821 PRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQA 880
Query: 658 IIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGG 717
G+ L P+ Y+ +V N G G P + T P+ AP
Sbjct: 881 SFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDG-PRSETKEFTTPEGVPS-APRRFRVRQ 938
Query: 718 GRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPS 777
+ + W E+ G GY + + F+G + K V N + + P
Sbjct: 939 PNLETINLEWD--HPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPV 996
Query: 778 TAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEA 811
+ ++ + A G G AV + P+EA
Sbjct: 997 SRYRFTLSARTQVGSGE----AVTEESPAPPNEA 1026
>gi|89903008 neurofascin isoform 4 precursor [Homo sapiens]
Length = 1169
Score = 365 bits (937), Expect = e-100
Identities = 281/926 (30%), Positives = 412/926 (44%), Gaps = 87/926 (9%)
Query: 61 VSLNCRARASPFPVYKWRMNNGDVDLTSD-RYSMV--GGNLVIN-----NPDKQKDAGIY 112
+ + C A+ +P P + W N+ ++ D R SM G LVI+ P++ + G Y
Sbjct: 53 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYE--GEY 110
Query: 113 YCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRW 172
C A N +G S L +P E V V+EG + L C+PP P + + W
Sbjct: 111 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIF-W 169
Query: 173 LLNEFPVFITMDKRRFVSQ-TNGNLYIANVEASD-KGNYSCFVSSPSITKSVFSKFIPLI 230
+ + IT DKR VSQ NG+LY +NV D + +YSC T ++ K
Sbjct: 170 MSSSMEP-ITQDKR--VSQGHNGDLYFSNVMLQDMQTDYSCNARF-HFTHTIQQK--NPF 223
Query: 231 PIPERTTKPYPADIVVQFKDVYA-----------------------LMGQNVTLECFALG 267
+ T PY + D+Y+ L G ++ LEC A G
Sbjct: 224 TLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASG 283
Query: 268 NPVPDIRWRKVLEPMPS-TAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIY 326
P PDI W K +PS A+ L+I N+ ED G Y C A N G +H +
Sbjct: 284 VPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVR 343
Query: 327 VQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHK----------GEL 376
V+A P W++ + + G D C A G P PT++W+ NG G+
Sbjct: 344 VKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT 403
Query: 377 RLY-DVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIE 435
++ D + +YQC N +G + ANA + +L + P ++P + I R ++
Sbjct: 404 IIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRM-LSPRNQLIRVILYNRTRLD 462
Query: 436 CKPKAAPKPKFSWSK-GTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKAN 494
C +P P W K G ++ ++E+GSLEI I + D GIYTC A N GKA
Sbjct: 463 CPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAE 522
Query: 495 STGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENI 554
+ L + DPTRI P + G ++C DP+L LT W +
Sbjct: 523 NQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW--------LKDDEP 574
Query: 555 HYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIED 614
Y N M + L I + G YTC A T +D A A L V G P P L + D
Sbjct: 575 LYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGRPDRPRDLELTD 634
Query: 615 IRATSVALTWSRGSDNHSPISKYTIQTK--TILSDDWKDAKTDPPIIEGNMEAARAVDLI 672
+ SV LTW G N+SPI+ Y +Q + W D P G++ +A + L
Sbjct: 635 LAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYP----GSVNSA-VLRLS 689
Query: 673 PWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSR 732
P++ Y+FRV+A N +G PS+PS R +T GA P P DV G G R + ITW P++
Sbjct: 690 PYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNA 749
Query: 733 EYHYGNNFGYIVAFKPFDGEE-WKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKG 791
+G N YIV ++ + E W VTV RYV + ++++V+A N+ G
Sbjct: 750 TSAFGPNLRYIVKWRRRETREAWNNVTVWG---SRYVVGQTPV--YVPYEIRVQAENDFG 804
Query: 792 DGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIVESYQIRYWAAHDKE 851
GP + S +D P APTEV V+V++S+ IS+ W V V+ Y A + +E
Sbjct: 805 KGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRE 864
Query: 852 EAANRVQVTSQEYSAR----------LENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTK 901
+ + SQ+ + L P + Y +E+ N G GP S+ E T
Sbjct: 865 SSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTP 924
Query: 902 KAPPSQPPRIISSVRSGSRYIITWDH 927
+ PS P R + + WDH
Sbjct: 925 EGVPSAPRRFRVRQPNLETINLEWDH 950
Score = 68.2 bits (165), Expect = 4e-11
Identities = 92/403 (22%), Positives = 143/403 (35%), Gaps = 57/403 (14%)
Query: 230 IPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK-----VLEPMPS 284
I IP T+P P KD N+ +EC A GNP P W + + P
Sbjct: 25 IEIPMDLTQP-PTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPR 83
Query: 285 TAEISTSGAVLKIFNI---QLEDEGIYECEAENIRGKD-KHQARIYVQAFPEW-VEHIND 339
+ SG ++ F E EG Y+C A N G ++ R+ V P W E+++
Sbjct: 84 VSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP 143
Query: 340 TEVDIGSDLYWPC-VATGKPIPTIRWL----------KNGYAYHKGELRLYDVTFENAGM 388
V G+ L C G P P I W+ K H G+L +V ++
Sbjct: 144 VVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQT 203
Query: 389 -YQCIAENTYGAIYANAE---LKILALAP-----------------TFEMNP-------M 420
Y C A + LK+L P E P
Sbjct: 204 DYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGT 263
Query: 421 KKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGG 480
+ +G +++EC P P +W K L + + +L I N++ D G
Sbjct: 264 ASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSG 323
Query: 481 IYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVW 540
Y C A N G T ++ + + P N + GE+ + C A+ +P T W
Sbjct: 324 EYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNP--KPTVQW 381
Query: 541 SFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTC 583
NG + N + + + ++ R+ Q+ Y C
Sbjct: 382 MVNGEPLQSAPPNPNRE-----VAGDTIIFRDTQISSRAVYQC 419
Score = 53.9 bits (128), Expect = 7e-07
Identities = 43/180 (23%), Positives = 80/180 (44%), Gaps = 9/180 (5%)
Query: 57 LEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLA 116
L + L+C SP P +W N +L Y + + +++D GIY C+A
Sbjct: 455 LYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVA 514
Query: 117 SNNYGMVRSTEATLSFGYLDPFPPEERPEVRV-KEGKGMVLLCDPPYHFPDDLSYRWLLN 175
+N G E + DP PE +V + G + L C + L+ WL +
Sbjct: 515 TNILG---KAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 571
Query: 176 EFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPER 235
+ P++I + + + +L I V D+G+Y+C V+S + + + ++ ++ P+R
Sbjct: 572 DEPLYI----GNRMKKEDDSLTIFGVAERDQGSYTC-VASTELDQDLAKAYLTVLGRPDR 626
Score = 37.4 bits (85), Expect = 0.072
Identities = 43/216 (19%), Positives = 78/216 (36%), Gaps = 13/216 (6%)
Query: 603 PPGPPGGLRIEDIRATSVALTWSRGSDNH-----SPISKYTIQTKTILSDDWKDAKTDPP 657
P P +++ + +T+++L W+R + Y + ++L + W K
Sbjct: 821 PRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQA 880
Query: 658 IIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGG 717
G+ L P+ Y+ +V N G G P + T P+ AP
Sbjct: 881 SFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDG-PRSETKEFTTPEGVPS-APRRFRVRQ 938
Query: 718 GRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPS 777
+ + W E+ G GY + + F+G + K V N + + P
Sbjct: 939 PNLETINLEWD--HPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPV 996
Query: 778 TAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPT 813
+ ++ + A G G AV + P+EA T
Sbjct: 997 SRYRFTLSARTQVGSGE----AVTEESPAPPNEAYT 1028
>gi|237858677 neurofascin isoform 2 precursor [Homo sapiens]
Length = 1189
Score = 357 bits (915), Expect = 4e-98
Identities = 281/941 (29%), Positives = 413/941 (43%), Gaps = 102/941 (10%)
Query: 61 VSLNCRARASPFPVYKWRMNNGDVDLTSD-RYSMV--GGNLVIN-----NPDKQKDAGIY 112
+ + C A+ +P P + W N+ ++ D R SM G LVI+ P++ + G Y
Sbjct: 53 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYE--GEY 110
Query: 113 YCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRW 172
C A N +G S L +P E V V+EG + L C+PP P + + W
Sbjct: 111 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIF-W 169
Query: 173 LLNEFPVFITMDKRRFVSQ-TNGNLYIANVEASD-KGNYSCFVSSPSITKSVFSKFIPLI 230
+ + IT DKR VSQ NG+LY +NV D + +YSC T ++ K
Sbjct: 170 MSSSMEP-ITQDKR--VSQGHNGDLYFSNVMLQDMQTDYSCNARF-HFTHTIQQK--NPF 223
Query: 231 PIPERTTKPYPADIVVQFKDVYA-----------------------LMGQNVTLECFALG 267
+ T PY + D+Y+ L G ++ LEC A G
Sbjct: 224 TLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASG 283
Query: 268 NPVPDIRWRKVLEPMPS-TAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIY 326
P PDI W K +PS A+ L+I N+ ED G Y C A N G +H +
Sbjct: 284 VPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVR 343
Query: 327 VQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHK----------GEL 376
V+A P W++ + + G D C A G P PT++W+ NG G+
Sbjct: 344 VKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDT 403
Query: 377 RLY-DVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIE 435
++ D + +YQC N +G + ANA + +L + P ++P + I R ++
Sbjct: 404 IIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRM-LSPRNQLIRVILYNRTRLD 462
Query: 436 CKPKAAPKPKFSWSK-GTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKAN 494
C +P P W K G ++ ++E+GSLEI I + D GIYTC A N GKA
Sbjct: 463 CPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAE 522
Query: 495 STGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENI 554
+ L + DPTRI P + G ++C DP+L LT W +
Sbjct: 523 NQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSW--------LKDDEP 574
Query: 555 HYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVV-------------- 600
Y N M + L I + G YTC A T +D A A L V
Sbjct: 575 LYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAAL 634
Query: 601 -RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTK--TILSDDWKDAKTDPP 657
+G P P L + D+ SV LTW G N+SPI+ Y +Q + W D P
Sbjct: 635 PKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYP- 693
Query: 658 IIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGG 717
G++ +A + L P++ Y+FRV+A N +G PS+PS R +T GA P P DV G G
Sbjct: 694 ---GSVNSA-VLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEG 749
Query: 718 GRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEE-WKKVTVTNPDTGRYVHKDETMSP 776
R + ITW P++ +G N YIV ++ + E W VTV RYV +
Sbjct: 750 TRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWG---SRYVVGQTPV-- 804
Query: 777 STAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKI 836
++++V+A N+ G GP + S +D P APTEV V+V++S+ IS+ W V
Sbjct: 805 YVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDT 864
Query: 837 VESYQIRYWAAHDKEEAANRVQVTSQEYSAR----------LENLLPDTQYFIEVGACNS 886
V+ Y A + +E + + SQ+ + L P + Y +E+ N
Sbjct: 865 VQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNG 924
Query: 887 AGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDH 927
G GP S+ E T + PS P R + + WDH
Sbjct: 925 RGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDH 965
Score = 68.2 bits (165), Expect = 4e-11
Identities = 92/403 (22%), Positives = 143/403 (35%), Gaps = 57/403 (14%)
Query: 230 IPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK-----VLEPMPS 284
I IP T+P P KD N+ +EC A GNP P W + + P
Sbjct: 25 IEIPMDLTQP-PTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPR 83
Query: 285 TAEISTSGAVLKIFNI---QLEDEGIYECEAENIRGKD-KHQARIYVQAFPEW-VEHIND 339
+ SG ++ F E EG Y+C A N G ++ R+ V P W E+++
Sbjct: 84 VSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP 143
Query: 340 TEVDIGSDLYWPC-VATGKPIPTIRWL----------KNGYAYHKGELRLYDVTFENAGM 388
V G+ L C G P P I W+ K H G+L +V ++
Sbjct: 144 VVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQT 203
Query: 389 -YQCIAENTYGAIYANAE---LKILALAP-----------------TFEMNP-------M 420
Y C A + LK+L P E P
Sbjct: 204 DYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGT 263
Query: 421 KKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGG 480
+ +G +++EC P P +W K L + + +L I N++ D G
Sbjct: 264 ASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSG 323
Query: 481 IYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVW 540
Y C A N G T ++ + + P N + GE+ + C A+ +P T W
Sbjct: 324 EYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNP--KPTVQW 381
Query: 541 SFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTC 583
NG + N + + + ++ R+ Q+ Y C
Sbjct: 382 MVNGEPLQSAPPNPNRE-----VAGDTIIFRDTQISSRAVYQC 419
Score = 50.8 bits (120), Expect = 6e-06
Identities = 40/160 (25%), Positives = 69/160 (43%), Gaps = 8/160 (5%)
Query: 57 LEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLA 116
L + L+C SP P +W N +L Y + + +++D GIY C+A
Sbjct: 455 LYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVA 514
Query: 117 SNNYGMVRSTEATLSFGYLDPFPPEERPEVRV-KEGKGMVLLCDPPYHFPDDLSYRWLLN 175
+N G E + DP PE +V + G + L C + L+ WL +
Sbjct: 515 TNILG---KAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 571
Query: 176 EFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSS 215
+ P++I + + + +L I V D+G+Y+C S+
Sbjct: 572 DEPLYI----GNRMKKEDDSLTIFGVAERDQGSYTCVAST 607
Score = 36.6 bits (83), Expect = 0.12
Identities = 42/214 (19%), Positives = 77/214 (35%), Gaps = 13/214 (6%)
Query: 603 PPGPPGGLRIEDIRATSVALTWSRGSDNH-----SPISKYTIQTKTILSDDWKDAKTDPP 657
P P +++ + +T+++L W+R + Y + ++L + W K
Sbjct: 836 PRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQA 895
Query: 658 IIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGG 717
G+ L P+ Y+ +V N G G P + T P+ AP
Sbjct: 896 SFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDG-PRSETKEFTTPEGVPS-APRRFRVRQ 953
Query: 718 GRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPS 777
+ + W E+ G GY + + F+G + K V N + + P
Sbjct: 954 PNLETINLEWD--HPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPV 1011
Query: 778 TAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEA 811
+ ++ + A G G AV + P+EA
Sbjct: 1012 SRYRFTLSARTQVGSGE----AVTEESPAPPNEA 1041
>gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo
sapiens]
Length = 1253
Score = 345 bits (885), Expect = 1e-94
Identities = 280/967 (28%), Positives = 420/967 (43%), Gaps = 86/967 (8%)
Query: 29 GHGVSEEDKGFGPIFEEQPIN--TIYPEESLEGKVSLNCRARASPFPVYKWRMNN----- 81
GH V E P+ EQ ++P + +SL C A P ++W +
Sbjct: 28 GHHVMEP-----PVITEQSPRRLVVFPTDD----ISLKCEASGKPEVQFRWTRDGVHFKP 78
Query: 82 -GDVDLTSDRYSMVGGNLVINNPDK--QKDAGIYYCLASNNYGMVRSTEATLSFGYLDPF 138
++ +T + G + N Q+ GIY C ASN G S E L +
Sbjct: 79 KEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKW 138
Query: 139 PPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYI 198
P E V V+EG+ +VL C+PP + L W+ N + I D+R + Q NGNLY
Sbjct: 139 PKETVKPVEVEEGESVVLPCNPPPS-AEPLRIYWM-NSKILHIKQDERVTMGQ-NGNLYF 195
Query: 199 ANVEASDK-GNYSCFVSSPSITKSVFSKFIPLIPIPERTT--------KPYPADIVVQFK 249
ANV SD +Y C P T+++ K PI R KP
Sbjct: 196 ANVLTSDNHSDYICHAHFPG-TRTIIQKE----PIDLRVKATNSMIDRKPRLLFPTNSSS 250
Query: 250 DVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPST-AEISTSGAVLKIFNIQLEDEGIY 308
+ AL GQ + LEC A G P P I+W + PMP+ L++ + ED+G Y
Sbjct: 251 HLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEY 310
Query: 309 ECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNG 368
C AEN G +H + V+A P W+ G C G+P P + W NG
Sbjct: 311 RCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 370
Query: 369 -----------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEM 417
Y +G L L +V + + QC A N +G + ANA + ++ L P +
Sbjct: 371 IPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQL-PAKIL 429
Query: 418 NPMKKKILAAKGGRVIIECKPKAAPKPKFSW--SKGTEWLVNSSRILIWEDGSLEINNIT 475
+ +A +G + CK AP P W GT ++ R + +G+L I ++
Sbjct: 430 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTT-VLQDERFFPYANGTLGIRDLQ 488
Query: 476 RNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALD 535
ND G Y C A N++ L + D T+I P + G T C ASFDP+L
Sbjct: 489 ANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQ 548
Query: 536 LTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSAS 595
+ W +G + ++ Y F+ D G L+I + G Y+C A T +D +
Sbjct: 549 PSITWRGDGRDLQELGDSDKY---FIED--GRLVIHSLDYSDQGNYSCVASTELDVVESR 603
Query: 596 ADLVVRGPPGPPGGLRIEDIRA---TSVALTWSRGSDNHSPISKYTIQ--TKTILSDDWK 650
A L+V G PGP L + D+ + V ++WS D+++PI KY I+ K + + W
Sbjct: 604 AQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWY 663
Query: 651 DAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAP 710
P GN + + + L P++ Y FRV A N G GEPS S + T AAP P
Sbjct: 664 SLGKVP----GN-QTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNP 718
Query: 711 SDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGE-EWKKVTVTNPDTGRYVH 769
DV G G + ITW PL Y V ++P W++ V++P V
Sbjct: 719 VDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFL--VVS 776
Query: 770 KDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHW 829
T P +++KV+A N++G GP V + S +D P P G+++L+SS + V W
Sbjct: 777 NTSTFVP---YEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKW 833
Query: 830 EHV----LEKIVESYQIRYWAAHDKEEAANR------VQVTSQEYSARLENLLPDTQYFI 879
V ++ + Y + YW + + + R V V + S L L P + Y +
Sbjct: 834 RPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHL 893
Query: 880 EVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTG 939
EV A N G GP S+ + T + P P + +S + ++ W LS+ +TG
Sbjct: 894 EVQAFNGRGSGPASEFTFS-TPEGVPGHPEALHLECQSNTSLLLRWQ--PPLSHNGVLTG 950
Query: 940 YKVLYRP 946
Y + Y P
Sbjct: 951 YVLSYHP 957
Score = 41.2 bits (95), Expect = 0.005
Identities = 54/217 (24%), Positives = 84/217 (38%), Gaps = 31/217 (14%)
Query: 819 VLSSSEISVHWEHVLEKI--VESYQIRYWAAHDKEEAANRV----QVTSQEYSARLENLL 872
+L+ S++ V W + +E Y I + DKE A + +V + S L+ L
Sbjct: 625 LLTQSQVRVSWSPAEDHNAPIEKYDIEF---EDKEMAPEKWYSLGKVPGNQTSTTLK-LS 680
Query: 873 PDTQYFIEVGACNSAGCGPPSDMIEAFT--KKAPPSQPPRIISSVRSGSRYIITWDHVVA 930
P Y V A N G G PS + E + AP P + + +ITW +
Sbjct: 681 PYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRW 740
Query: 931 LSNESTVTGYKVLYRPDGQH--------DGKLYSTHKHSIEVPIPRDGEYVVEVRAHSDG 982
+ + Y+V +RP G S VP Y ++V+A +
Sbjct: 741 MDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVP------YEIKVQAVNSQ 794
Query: 983 GDGVVSQVKISGA----PTLSPSLLGL-LLPAFGILV 1014
G G QV I + P P L G+ +L + +LV
Sbjct: 795 GKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLV 831
Score = 33.5 bits (75), Expect = 1.0
Identities = 33/140 (23%), Positives = 53/140 (37%), Gaps = 7/140 (5%)
Query: 655 DPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVG 714
D ++ N + L P+ Y V A N GRG T P P +
Sbjct: 869 DHVVVPANTTSVILSGLRPYSSYHLEVQAFN--GRGSGPASEFTFSTPEGVPG-HPEALH 925
Query: 715 GGGGRNRELTITWAP-LSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDET 773
N L + W P LS H G GY++++ P D +++ D H
Sbjct: 926 LECQSNTSLLLRWQPPLS---HNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTD 982
Query: 774 MSPSTAFQVKVKAFNNKGDG 793
+SP ++ +++A +G G
Sbjct: 983 LSPHLRYRFQLQATTKEGPG 1002
>gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo
sapiens]
Length = 1257
Score = 345 bits (885), Expect = 1e-94
Identities = 280/967 (28%), Positives = 420/967 (43%), Gaps = 86/967 (8%)
Query: 29 GHGVSEEDKGFGPIFEEQPIN--TIYPEESLEGKVSLNCRARASPFPVYKWRMNN----- 81
GH V E P+ EQ ++P + +SL C A P ++W +
Sbjct: 28 GHHVMEP-----PVITEQSPRRLVVFPTDD----ISLKCEASGKPEVQFRWTRDGVHFKP 78
Query: 82 -GDVDLTSDRYSMVGGNLVINNPDK--QKDAGIYYCLASNNYGMVRSTEATLSFGYLDPF 138
++ +T + G + N Q+ GIY C ASN G S E L +
Sbjct: 79 KEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKW 138
Query: 139 PPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYI 198
P E V V+EG+ +VL C+PP + L W+ N + I D+R + Q NGNLY
Sbjct: 139 PKETVKPVEVEEGESVVLPCNPPPS-AEPLRIYWM-NSKILHIKQDERVTMGQ-NGNLYF 195
Query: 199 ANVEASDK-GNYSCFVSSPSITKSVFSKFIPLIPIPERTT--------KPYPADIVVQFK 249
ANV SD +Y C P T+++ K PI R KP
Sbjct: 196 ANVLTSDNHSDYICHAHFPG-TRTIIQKE----PIDLRVKATNSMIDRKPRLLFPTNSSS 250
Query: 250 DVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPST-AEISTSGAVLKIFNIQLEDEGIY 308
+ AL GQ + LEC A G P P I+W + PMP+ L++ + ED+G Y
Sbjct: 251 HLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEY 310
Query: 309 ECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNG 368
C AEN G +H + V+A P W+ G C G+P P + W NG
Sbjct: 311 RCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 370
Query: 369 -----------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEM 417
Y +G L L +V + + QC A N +G + ANA + ++ L P +
Sbjct: 371 IPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQL-PAKIL 429
Query: 418 NPMKKKILAAKGGRVIIECKPKAAPKPKFSW--SKGTEWLVNSSRILIWEDGSLEINNIT 475
+ +A +G + CK AP P W GT ++ R + +G+L I ++
Sbjct: 430 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTT-VLQDERFFPYANGTLGIRDLQ 488
Query: 476 RNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALD 535
ND G Y C A N++ L + D T+I P + G T C ASFDP+L
Sbjct: 489 ANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQ 548
Query: 536 LTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSAS 595
+ W +G + ++ Y F+ D G L+I + G Y+C A T +D +
Sbjct: 549 PSITWRGDGRDLQELGDSDKY---FIED--GRLVIHSLDYSDQGNYSCVASTELDVVESR 603
Query: 596 ADLVVRGPPGPPGGLRIEDIRA---TSVALTWSRGSDNHSPISKYTIQ--TKTILSDDWK 650
A L+V G PGP L + D+ + V ++WS D+++PI KY I+ K + + W
Sbjct: 604 AQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWY 663
Query: 651 DAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAP 710
P GN + + + L P++ Y FRV A N G GEPS S + T AAP P
Sbjct: 664 SLGKVP----GN-QTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNP 718
Query: 711 SDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGE-EWKKVTVTNPDTGRYVH 769
DV G G + ITW PL Y V ++P W++ V++P V
Sbjct: 719 VDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFL--VVS 776
Query: 770 KDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHW 829
T P +++KV+A N++G GP V + S +D P P G+++L+SS + V W
Sbjct: 777 NTSTFVP---YEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKW 833
Query: 830 EHV----LEKIVESYQIRYWAAHDKEEAANR------VQVTSQEYSARLENLLPDTQYFI 879
V ++ + Y + YW + + + R V V + S L L P + Y +
Sbjct: 834 RPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHL 893
Query: 880 EVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTG 939
EV A N G GP S+ + T + P P + +S + ++ W LS+ +TG
Sbjct: 894 EVQAFNGRGSGPASEFTFS-TPEGVPGHPEALHLECQSNTSLLLRWQ--PPLSHNGVLTG 950
Query: 940 YKVLYRP 946
Y + Y P
Sbjct: 951 YVLSYHP 957
Score = 41.2 bits (95), Expect = 0.005
Identities = 54/217 (24%), Positives = 84/217 (38%), Gaps = 31/217 (14%)
Query: 819 VLSSSEISVHWEHVLEKI--VESYQIRYWAAHDKEEAANRV----QVTSQEYSARLENLL 872
+L+ S++ V W + +E Y I + DKE A + +V + S L+ L
Sbjct: 625 LLTQSQVRVSWSPAEDHNAPIEKYDIEF---EDKEMAPEKWYSLGKVPGNQTSTTLK-LS 680
Query: 873 PDTQYFIEVGACNSAGCGPPSDMIEAFT--KKAPPSQPPRIISSVRSGSRYIITWDHVVA 930
P Y V A N G G PS + E + AP P + + +ITW +
Sbjct: 681 PYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRW 740
Query: 931 LSNESTVTGYKVLYRPDGQH--------DGKLYSTHKHSIEVPIPRDGEYVVEVRAHSDG 982
+ + Y+V +RP G S VP Y ++V+A +
Sbjct: 741 MDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVP------YEIKVQAVNSQ 794
Query: 983 GDGVVSQVKISGA----PTLSPSLLGL-LLPAFGILV 1014
G G QV I + P P L G+ +L + +LV
Sbjct: 795 GKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLV 831
Score = 33.5 bits (75), Expect = 1.0
Identities = 33/140 (23%), Positives = 53/140 (37%), Gaps = 7/140 (5%)
Query: 655 DPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVG 714
D ++ N + L P+ Y V A N GRG T P P +
Sbjct: 869 DHVVVPANTTSVILSGLRPYSSYHLEVQAFN--GRGSGPASEFTFSTPEGVPG-HPEALH 925
Query: 715 GGGGRNRELTITWAP-LSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDET 773
N L + W P LS H G GY++++ P D +++ D H
Sbjct: 926 LECQSNTSLLLRWQPPLS---HNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTD 982
Query: 774 MSPSTAFQVKVKAFNNKGDG 793
+SP ++ +++A +G G
Sbjct: 983 LSPHLRYRFQLQATTKEGPG 1002
>gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo
sapiens]
Length = 1248
Score = 344 bits (882), Expect = 3e-94
Identities = 276/955 (28%), Positives = 416/955 (43%), Gaps = 81/955 (8%)
Query: 41 PIFEEQPIN--TIYPEESLEGKVSLNCRARASPFPVYKWRMNN------GDVDLTSDRYS 92
P+ EQ ++P + +SL C A P ++W + ++ +T +
Sbjct: 30 PVITEQSPRRLVVFPTDD----ISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSP 85
Query: 93 MVGGNLVINNPDK--QKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKE 150
G + N Q+ GIY C ASN G S E L +P E V V+E
Sbjct: 86 HSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEE 145
Query: 151 GKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDK-GNY 209
G+ +VL C+PP + L W+ N + I D+R + Q NGNLY ANV SD +Y
Sbjct: 146 GESVVLPCNPPPS-AEPLRIYWM-NSKILHIKQDERVTMGQ-NGNLYFANVLTSDNHSDY 202
Query: 210 SCFVSSPSITKSVFSKFIPLIPIPERTT--------KPYPADIVVQFKDVYALMGQNVTL 261
C P T+++ K PI R KP + AL GQ + L
Sbjct: 203 ICHAHFPG-TRTIIQKE----PIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVL 257
Query: 262 ECFALGNPVPDIRWRKVLEPMPST-AEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDK 320
EC A G P P I+W + PMP+ L++ + ED+G Y C AEN G +
Sbjct: 258 ECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSAR 317
Query: 321 HQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNG-----------Y 369
H + V+A P W+ G C G+P P + W NG Y
Sbjct: 318 HAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKY 377
Query: 370 AYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKG 429
+G L L +V + + QC A N +G + ANA + ++ L P + + +A +G
Sbjct: 378 RIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQL-PAKILTADNQTYMAVQG 436
Query: 430 GRVIIECKPKAAPKPKFSW--SKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAE 487
+ CK AP P W GT ++ R + +G+L I ++ ND G Y C A
Sbjct: 437 STAYLLCKAFGAPVPSVQWLDEDGTT-VLQDERFFPYANGTLGIRDLQANDTGRYFCLAA 495
Query: 488 NNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVI 547
N++ L + D T+I P + G T C ASFDP+L + W +G +
Sbjct: 496 NDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDL 555
Query: 548 DFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPP 607
++ Y F+ D G L+I + G Y+C A T +D + A L+V G PGP
Sbjct: 556 QELGDSDKY---FIED--GRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPV 610
Query: 608 GGLRIEDIRA---TSVALTWSRGSDNHSPISKYTIQ--TKTILSDDWKDAKTDPPIIEGN 662
L + D+ + V ++WS D+++PI KY I+ K + + W P GN
Sbjct: 611 PRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVP----GN 666
Query: 663 MEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRE 722
+ + + L P++ Y FRV A N G GEPS S + T AAP P DV G G
Sbjct: 667 -QTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTN 725
Query: 723 LTITWAPLSREYHYGNNFGYIVAFKPFDGE-EWKKVTVTNPDTGRYVHKDETMSPSTAFQ 781
+ ITW PL Y V ++P W++ V++P V T P ++
Sbjct: 726 MVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFL--VVSNTSTFVP---YE 780
Query: 782 VKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHV----LEKIV 837
+KV+A N++G GP V + S +D P P G+++L+SS + V W V ++ +
Sbjct: 781 IKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHL 840
Query: 838 ESYQIRYWAAHDKEEAANR------VQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGP 891
Y + YW + + + R V V + S L L P + Y +EV A N G GP
Sbjct: 841 RGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGP 900
Query: 892 PSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRP 946
S+ + T + P P + +S + ++ W LS+ +TGY + Y P
Sbjct: 901 ASEFTFS-TPEGVPGHPEALHLECQSNTSLLLRWQ--PPLSHNGVLTGYVLSYHP 952
Score = 41.2 bits (95), Expect = 0.005
Identities = 54/217 (24%), Positives = 84/217 (38%), Gaps = 31/217 (14%)
Query: 819 VLSSSEISVHWEHVLEKI--VESYQIRYWAAHDKEEAANRV----QVTSQEYSARLENLL 872
+L+ S++ V W + +E Y I + DKE A + +V + S L+ L
Sbjct: 620 LLTQSQVRVSWSPAEDHNAPIEKYDIEF---EDKEMAPEKWYSLGKVPGNQTSTTLK-LS 675
Query: 873 PDTQYFIEVGACNSAGCGPPSDMIEAFT--KKAPPSQPPRIISSVRSGSRYIITWDHVVA 930
P Y V A N G G PS + E + AP P + + +ITW +
Sbjct: 676 PYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRW 735
Query: 931 LSNESTVTGYKVLYRPDGQH--------DGKLYSTHKHSIEVPIPRDGEYVVEVRAHSDG 982
+ + Y+V +RP G S VP Y ++V+A +
Sbjct: 736 MDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVP------YEIKVQAVNSQ 789
Query: 983 GDGVVSQVKISGA----PTLSPSLLGL-LLPAFGILV 1014
G G QV I + P P L G+ +L + +LV
Sbjct: 790 GKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLV 826
Score = 33.5 bits (75), Expect = 1.0
Identities = 33/140 (23%), Positives = 53/140 (37%), Gaps = 7/140 (5%)
Query: 655 DPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVG 714
D ++ N + L P+ Y V A N GRG T P P +
Sbjct: 864 DHVVVPANTTSVILSGLRPYSSYHLEVQAFN--GRGSGPASEFTFSTPEGVPG-HPEALH 920
Query: 715 GGGGRNRELTITWAP-LSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDET 773
N L + W P LS H G GY++++ P D +++ D H
Sbjct: 921 LECQSNTSLLLRWQPPLS---HNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTD 977
Query: 774 MSPSTAFQVKVKAFNNKGDG 793
+SP ++ +++A +G G
Sbjct: 978 LSPHLRYRFQLQATTKEGPG 997
>gi|27894376 cell adhesion molecule with homology to L1CAM precursor
[Homo sapiens]
Length = 1224
Score = 344 bits (882), Expect = 3e-94
Identities = 267/962 (27%), Positives = 426/962 (44%), Gaps = 86/962 (8%)
Query: 42 IFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVIN 101
I ++ + +P + + C A+ +P P + W + T R +
Sbjct: 37 IIKQSKVQVAFPFDEY---FQIECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTFR 93
Query: 102 NPDKQKDA---GIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLC 158
P++ + G Y C ASN G+ S E + FP E+ + V+EG +VL C
Sbjct: 94 IPNEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPIVLPC 153
Query: 159 DPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGN-YSCFVSSPS 217
+PP P L W+ E I D+R ++SQ G+LY ANVE D N Y CF + P
Sbjct: 154 NPPKGLPP-LHIYWMNIELE-HIEQDERVYMSQ-KGDLYFANVEEKDSRNDYCCFAAFPR 210
Query: 218 ITKSVFSKFIPLIPI---------PERTTKPYPADIVVQFK--------------DVYAL 254
+ +++ K + + T A+ + Q K + L
Sbjct: 211 L-RTIVQKMPMKLTVNSLKHANDSSSSTEIGSKANSIKQRKPKLLLPPTESGSESSITIL 269
Query: 255 MGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEISTS-GAVLKIFNIQLEDEGIYECEAE 313
G+ + LECFA G P P + W K+ +P E + G LKI N+ +D+G Y C A
Sbjct: 270 KGEILLLECFAEGLPTPQVDWNKIGGDLPKGRETKENYGKTLKIENVSYQDKGNYRCTAS 329
Query: 314 NIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNG----- 368
N G H + V+ P W + GS+ C A G+P PTI+W NG
Sbjct: 330 NFLGTATHDFHVIVEEPPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPVDN 389
Query: 369 YAYHKGELRLYDVTFEN-----AGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKK 423
+ + + +++F N +YQC A N +G I ANA + ++ + P + +
Sbjct: 390 HPFAGDVVFPREISFTNLQPNHTAVYQCEASNVHGTILANANIDVVDVRPLIQTKD-GEN 448
Query: 424 ILAAKGGRVIIECKPKAAPKPKFSWSKGTEWL-VNSSRILIWEDGSLEINNITRNDGGIY 482
G + C+ A+P+ SW K E + R I+E+G+L+IN T D G Y
Sbjct: 449 YATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYENGTLQINRTTEEDAGSY 508
Query: 483 TCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPAL--DLTFVW 540
+C+ EN GK T L I + T++ ++P N I + C + D L L W
Sbjct: 509 SCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHCESKCDSHLKHSLKLSW 568
Query: 541 SFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVV 600
S +G + N + ++ L I N L+ G Y C+A T +D+++ + V
Sbjct: 569 SKDGEAFEINGT----EDGRIIIDGANLTISNVTLEDQGIYCCSAHTALDSAADITQVTV 624
Query: 601 RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDD--WKDAKTDPPI 658
P PP L + + + SV LTW G+D++S IS+Y ++ + + W++
Sbjct: 625 LDVPDPPENLHLSERQNRSVRLTWEAGADHNSNISEYIVEFEGNKEEPGRWEELTR---- 680
Query: 659 IEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGG 718
++G + L P++ Y+FRV+A N +GR +PS PS+ +T AAP+ P ++
Sbjct: 681 VQGKKTTV-ILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQAS 739
Query: 719 RNRELTITWAPLSREYHYGNNFGYIVAFKPFDGE-EWKKVTVTNPDTGRYVHKDETMSPS 777
+ +E+ I W PL G Y V +KP EW++ TVTN H M+P+
Sbjct: 740 QPKEMIIKWEPLKSMEQNGPGLEYRVTWKPQGAPVEWEEETVTN-------HTLRVMTPA 792
Query: 778 --TAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEK 835
+ VKV+A N G GP + S +D P AP GV V++S+ + V W V +
Sbjct: 793 VYAPYDVKVQAINQLGSGPDPQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTWSTVPKD 852
Query: 836 IV----ESYQIRYW--------AAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGA 883
V + YQI +W H KE N ++ + Q S + +L +++ + V A
Sbjct: 853 RVHGRLKGYQINWWKTKSLLDGRTHPKE--VNILRFSGQRNSGMVPSLDAFSEFHLTVLA 910
Query: 884 CNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVL 943
NS G GP S+ T + P QP + ++W L+ +TGY +
Sbjct: 911 YNSKGAGPESEPYIFQTPEGVPEQPTFLKVIKVDKDTATLSWGLPKKLN--GNLTGYLLQ 968
Query: 944 YR 945
Y+
Sbjct: 969 YQ 970
Score = 126 bits (317), Expect = 9e-29
Identities = 211/948 (22%), Positives = 361/948 (38%), Gaps = 123/948 (12%)
Query: 27 RYGHGVSEEDKGFGPIFEEQPINTIYPEESLEGK-VSLNCRARASPFPVYKWRMNNGDVD 85
+ G +SEE + P + P I P E EG + L C P++ + MN
Sbjct: 114 KLGIAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPIVLPCNPPKGLPPLHIYWMNIELEH 173
Query: 86 LTSDR--YSMVGGNLVINNPDKQKDAGIYYCLAS-----------------NNYGMVRST 126
+ D Y G+L N +++ Y C A+ N+ +
Sbjct: 174 IEQDERVYMSQKGDLYFANVEEKDSRNDYCCFAAFPRLRTIVQKMPMKLTVNSLKHANDS 233
Query: 127 EATLSFG-------------YLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWL 173
++ G L P + + +G+ ++L C + + +
Sbjct: 234 SSSTEIGSKANSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGLPTPQVDWNKI 293
Query: 174 LNEFPVFITMDKRRFVSQTNGN-LYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPI 232
+ P K R + G L I NV DKGNY C S+ + F ++
Sbjct: 294 GGDLP------KGRETKENYGKTLKIENVSYQDKGNYRCTASN--FLGTATHDFHVIVEE 345
Query: 233 PER-TTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPM---PSTAEI 288
P R T KP A VY+ G N L C A G P P I+WR P+ P ++
Sbjct: 346 PPRWTKKPQSA--------VYST-GSNGILLCEAEGEPQPTIKWRVNGSPVDNHPFAGDV 396
Query: 289 STSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTE---VDIG 345
+ N+Q +Y+CEA N+ G A I V ++ D E +G
Sbjct: 397 VFPREI-SFTNLQPNHTAVYQCEASNVHGTILANANIDVVDVRPLIQ-TKDGENYATVVG 454
Query: 346 SDLYWPCVATGKPIPTIRWLK-------NGYAYH---KGELRLYDVTFENAGMYQCIAEN 395
+ C P + W K G YH G L++ T E+AG Y C EN
Sbjct: 455 YSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYENGTLQINRTTEEDAGSYSCWVEN 514
Query: 396 TYG--AIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAP----KPKFSWS 449
G A+ AN +++ NP K+ + + C+ K K SWS
Sbjct: 515 AIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLE-----LHCESKCDSHLKHSLKLSWS 569
Query: 450 K-GTEWLVNSS---RILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPT 505
K G + +N + RI+I + +L I+N+T D GIY C A A + + D
Sbjct: 570 KDGEAFEINGTEDGRIII-DGANLTISNVTLEDQGIYCCSAHTALDSAADITQVTVLD-- 626
Query: 506 RIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDF--NKENI-HYQRNFML 562
+ P N ++ +N +++ +++ D + + Y+++F NKE ++ +
Sbjct: 627 -VPDPPENLHLSERQNRSVRL--TWEAGADHNS--NISEYIVEFEGNKEEPGRWEELTRV 681
Query: 563 DSNGELLIRNAQ--LKHAGRYTCTAQTIVDNSSASADLVVRGPPGP---PGGLRIEDIRA 617
+I +++ R + S +D P P P +R++ +
Sbjct: 682 QGKKTTVILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQP 741
Query: 618 TSVALTWS--RGSDNHSPISKYTIQTKTILSD-DWKDAKTDPPIIEGNMEAARAVDLIPW 674
+ + W + + + P +Y + K + +W++ R + +
Sbjct: 742 KEMIIKWEPLKSMEQNGPGLEYRVTWKPQGAPVEWEEETV-------TNHTLRVMTPAVY 794
Query: 675 MEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREY 734
Y+ +V A N LG G P S + + P+ AP G + + +TW+ + ++
Sbjct: 795 APYDVKVQAINQLGSG-PDPQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTWSTVPKDR 853
Query: 735 HYGNNFGYIVAF----KPFDGEEW-KKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNN 789
+G GY + + DG K+V + R ++ + F + V A+N+
Sbjct: 854 VHGRLKGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDAFSEFHLTVLAYNS 913
Query: 790 KGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHW--EHVLEKIVESYQIRYWAA 847
KG GP S + + + P E PT + V + ++ W L + Y ++Y
Sbjct: 914 KGAGPESEPYIFQTPEGVP-EQPTFLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQII 972
Query: 848 HDKEEAA--NRVQVTS-QEYSARLENLLPDTQYFIEVGACNSAGCGPP 892
+D E N + +T+ + S L NL T+Y + AC S GCG P
Sbjct: 973 NDTYEIGELNDINITTPSKPSWHLSNLNATTKYKFYLRACTSQGCGKP 1020
Score = 74.3 bits (181), Expect = 5e-13
Identities = 182/847 (21%), Positives = 288/847 (34%), Gaps = 142/847 (16%)
Query: 225 KFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPS 284
KF I IP + + P I V + +EC A GNP P W K P
Sbjct: 20 KFSKAIEIPS-SVQQVPTIIKQSKVQVAFPFDEYFQIECEAKGNPEPTFSWTKDGNPFYF 78
Query: 285 TAEISTSGAVLKIFNIQLED-----EGIYECEAENIRG-KDKHQARIYVQAFPEWV-EHI 337
T F I E +G Y C A N G + V + P++ E I
Sbjct: 79 TDHRIIPSNNSGTFRIPNEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSVPKFPKEKI 138
Query: 338 NDTEVDIGSDLYWPC-VATGKPIPTIRWLKNGYAYHKGELRLY-----DVTFENA----- 386
+ EV+ G + PC G P I W+ + + + R+Y D+ F N
Sbjct: 139 DPLEVEEGDPIVLPCNPPKGLPPLHIYWMNIELEHIEQDERVYMSQKGDLYFANVEEKDS 198
Query: 387 -GMYQCIA----------------------------ENTYGAIYANA--ELKILALAPTF 415
Y C A +T AN+ + K L P
Sbjct: 199 RNDYCCFAAFPRLRTIVQKMPMKLTVNSLKHANDSSSSTEIGSKANSIKQRKPKLLLPPT 258
Query: 416 EMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNIT 475
E + I KG +++EC + P P+ W+K L +L+I N++
Sbjct: 259 ESGS-ESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGRETKENYGKTLKIENVS 317
Query: 476 RNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALD 535
D G Y C A N G A +++ +P R P +A + G N + C A +P
Sbjct: 318 YQDKGNYRCTASNFLGTATHDFHVIVEEPPRWTKKPQSAVYSTGSNGILLCEAEGEP--Q 375
Query: 536 LTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDN--SS 593
T W NG +D N + + + E+ N Q H Y C A + ++
Sbjct: 376 PTIKWRVNGSPVD----NHPFAGDVVFPR--EISFTNLQPNHTAVYQCEASNVHGTILAN 429
Query: 594 ASADLVVRGP-------------PGPPGGLRIEDIRATSVALTWSRGSD-------NHSP 633
A+ D+V P G L E + ++W + + +
Sbjct: 430 ANIDVVDVRPLIQTKDGENYATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHI 489
Query: 634 ISKYTIQTKTILSDD------WKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTL 687
T+Q +D W + + N++ A L RV N
Sbjct: 490 YENGTLQINRTTEEDAGSYSCWVENAIGKTAVTANLDIRNATKL--------RVSPKN-- 539
Query: 688 GRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHY-GNNFGYIVAF 746
P IP + + + S + L ++W+ + G G I+
Sbjct: 540 ----PRIPKLHM-LELHCESKCDSHL------KHSLKLSWSKDGEAFEINGTEDGRII-- 586
Query: 747 KPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQD 806
DG VT D G Y T S A +V + D P +L ++ Q+
Sbjct: 587 --IDGANLTISNVTLEDQGIYCCSAHTALDSAADITQVTVLDVP-DPPENLH--LSERQN 641
Query: 807 APSEAPTEVGVKVLSSSEISVHWEHVLEKIVESYQIRYWAAHDKEEAANRVQVTSQE--Y 864
E G H ++ E IVE +KEE ++T +
Sbjct: 642 RSVRLTWEAGAD---------HNSNISEYIVEF-------EGNKEEPGRWEELTRVQGKK 685
Query: 865 SARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVR----SGSR 920
+ + L P +Y V A N G PS + + PP+ P R ++R
Sbjct: 686 TTVILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHH--ETPPAAPDRNPQNIRVQASQPKE 743
Query: 921 YIITWDHVVALSNESTVTGYKVLYRPDGQH-DGKLYSTHKHSIEVPIPR-DGEYVVEVRA 978
II W+ + ++ Y+V ++P G + + + H++ V P Y V+V+A
Sbjct: 744 MIIKWEPLKSMEQNGPGLEYRVTWKPQGAPVEWEEETVTNHTLRVMTPAVYAPYDVKVQA 803
Query: 979 HSDGGDG 985
+ G G
Sbjct: 804 INQLGSG 810
>gi|237858675 neurofascin isoform 1 precursor [Homo sapiens]
Length = 1240
Score = 337 bits (864), Expect = 3e-92
Identities = 275/932 (29%), Positives = 411/932 (44%), Gaps = 88/932 (9%)
Query: 61 VSLNCRARASPFPVYKWRMNNGDVDLTSD-RYSMV--GGNLVIN-----NPDKQKDAGIY 112
+ + C A+ +P P + W N+ ++ D R SM G LVI+ P++ + G Y
Sbjct: 59 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYE--GEY 116
Query: 113 YCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRW 172
C A N +G S L +P E V V+EG + L C+PP P + + W
Sbjct: 117 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIF-W 175
Query: 173 LLNEFPVFITMDKRRFVSQT-NGNLYIANVEASD-KGNYSC-----FVSSPSITKSVFSK 225
+ + IT DKR VSQ NG+LY +NV D + +YSC F + K
Sbjct: 176 MSSSMEP-ITQDKR--VSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLK 232
Query: 226 FIPLIPIPERTTK-PYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPS 284
+ + ERT YP L G ++ LEC A G P PDI W K +PS
Sbjct: 233 VLTTRGVAERTPSFMYPQGTA---SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS 289
Query: 285 T-AEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVD 343
A+ L+I N+ ED G Y C A N G +H + V+A P W++ + +
Sbjct: 290 DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA 349
Query: 344 IGSDLYWPCVATGKPIPTIRWLKNGYAYHK----------GELRLY-DVTFENAGMYQCI 392
G D C A G P PT++W+ NG G+ ++ D + +YQC
Sbjct: 350 PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCN 409
Query: 393 AENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSK-G 451
N +G + ANA + +L + P ++P + I R ++C +P P W K G
Sbjct: 410 TSNEHGYLLANAFVSVLDVPPRM-LSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNG 468
Query: 452 TEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAP 511
++ ++E+GSLEI I + D GIYTC A N GKA + L + DPTRI P
Sbjct: 469 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMP 528
Query: 512 INADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIR 571
+ G ++C DP+L LT W + Y N M + L I
Sbjct: 529 EDQVARRGTTVQLECRVKHDPSLKLTVSW--------LKDDEPLYIGNRMKKEDDSLTIF 580
Query: 572 NAQLKHAGRYTCTAQTIVDNSSASADLVV---------------RGPPGPPGGLRIEDIR 616
+ G YTC A T +D A A L V +G P P L + D+
Sbjct: 581 GVAERDQGSYTCVASTELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLA 640
Query: 617 ATSVALTWSRGSDNHSPISKYTIQTKT--ILSDDWKDAKTDPPIIEGNMEAARAVDLIPW 674
SV LTW G N+SPI+ Y +Q + W D P G++ +A + L P+
Sbjct: 641 ERSVRLTWIPGDANNSPITDYVVQFEEDQFQPGVWHDHSKYP----GSVNSA-VLRLSPY 695
Query: 675 MEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREY 734
+ Y+FRV+A N +G PS+PS R +T GA P P DV G G R + ITW P++
Sbjct: 696 VNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATS 755
Query: 735 HYGNNFGYIVAFKPFDGEE-WKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDG 793
+G N YIV ++ + E W VTV RYV + ++++V+A N+ G G
Sbjct: 756 AFGPNLRYIVKWRRRETREAWNNVTVWG---SRYVVGQTPV--YVPYEIRVQAENDFGKG 810
Query: 794 PYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEK--IVESYQIRYWAAHDKE 851
P + S +D PS AP V+ + I++ W+H I+ Y ++Y A + +
Sbjct: 811 PEPESVIGYSGEDLPS-APRRFRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTK 869
Query: 852 EAANRVQ-VTSQEYSARLENLLPDTQYFIEVGACNSAGCG------PPSDMIEAFTKKAP 904
V+ + + ++ P ++Y + A G G P+ EA AP
Sbjct: 870 VGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAP 929
Query: 905 PSQPPRIISSVRSGSRYIITWDHVVALSNEST 936
P+ PP + + + S T +A + E+T
Sbjct: 930 PTLPPTTVGATGAVSSTDAT---AIAATTEAT 958
Score = 76.3 bits (186), Expect = 1e-13
Identities = 89/383 (23%), Positives = 141/383 (36%), Gaps = 46/383 (12%)
Query: 233 PERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK-----VLEPMPSTAE 287
P TK D +V +D N+ +EC A GNP P W + + P +
Sbjct: 40 PPTITKQSAKDHIVDPRD-------NILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSM 92
Query: 288 ISTSGAVLKIFNI---QLEDEGIYECEAENIRGKD-KHQARIYVQAFPEW-VEHINDTEV 342
SG ++ F E EG Y+C A N G ++ R+ V P W E+++ V
Sbjct: 93 RRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVV 152
Query: 343 DIGSDLYWPC-VATGKPIPTIRWL----------KNGYAYHKGELRLYDVTFENAGM-YQ 390
G+ L C G P P I W+ K H G+L +V ++ Y
Sbjct: 153 QEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYS 212
Query: 391 CIAENTYGAIYANAE---LKILALAPTFEMNP-------MKKKILAAKGGRVIIECKPKA 440
C A + LK+L E P + +G +++EC
Sbjct: 213 CNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASG 272
Query: 441 APKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLV 500
P P +W K L + + +L I N++ D G Y C A N G T ++
Sbjct: 273 VPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVR 332
Query: 501 ITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNF 560
+ + P N + GE+ + C A+ +P T W NG + N + +
Sbjct: 333 VKAAPYWLDEPKNLILAPGEDGRLVCRANGNP--KPTVQWMVNGEPLQSAPPNPNRE--- 387
Query: 561 MLDSNGELLIRNAQLKHAGRYTC 583
+ ++ R+ Q+ Y C
Sbjct: 388 --VAGDTIIFRDTQISSRAVYQC 408
Score = 50.8 bits (120), Expect = 6e-06
Identities = 40/160 (25%), Positives = 69/160 (43%), Gaps = 8/160 (5%)
Query: 57 LEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLA 116
L + L+C SP P +W N +L Y + + +++D GIY C+A
Sbjct: 444 LYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVA 503
Query: 117 SNNYGMVRSTEATLSFGYLDPFPPEERPEVRV-KEGKGMVLLCDPPYHFPDDLSYRWLLN 175
+N G E + DP PE +V + G + L C + L+ WL +
Sbjct: 504 TNILG---KAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 560
Query: 176 EFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSS 215
+ P++I + + + +L I V D+G+Y+C S+
Sbjct: 561 DEPLYI----GNRMKKEDDSLTIFGVAERDQGSYTCVAST 596
>gi|81158224 neuronal cell adhesion molecule isoform B precursor
[Homo sapiens]
Length = 1183
Score = 312 bits (800), Expect = 9e-85
Identities = 261/948 (27%), Positives = 412/948 (43%), Gaps = 92/948 (9%)
Query: 61 VSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVG---GNLVINNPDKQKDA---GIYYC 114
+ + C A+ P P + W N D+ D + G L+IN + K G+Y C
Sbjct: 58 IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQC 117
Query: 115 LASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLL 174
A N G S + + E+ + ++ G+ +VL C PP P + + W+
Sbjct: 118 TARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIF-WMD 176
Query: 175 NEFPVFITMDKRRFVSQ-TNGNLYIANVEASD-KGNYSCFVSSPSITKSVFSK---FIPL 229
N F + + VSQ NG+LY +NV D + +Y C+ + T+++ K + +
Sbjct: 177 NSFQ---RLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARF-NHTQTIQQKQPISVKV 232
Query: 230 IPIPE-----------------RTTKPYPADIVV---QFKDVYALMGQNVTLECFALGNP 269
I + E ++++ P + + L G ++LEC A G P
Sbjct: 233 ISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLP 292
Query: 270 VPDIRWRKVLEPMPSTAEISTS-GAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQ 328
P I W K +P + + L+I ++ D G Y+C A+N G H + V+
Sbjct: 293 TPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVK 352
Query: 329 AFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYH----------KGELRL 378
A P W+ + + G D C A G P P I WL NG G+ +
Sbjct: 353 AAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII 412
Query: 379 Y-DVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECK 437
+ +V ++ +YQC A N YG + ANA + +LA P + P +++C
Sbjct: 413 FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRI-LTPANTLYQVIANRPALLDCA 471
Query: 438 PKAAPKPKFSWSKGTEW-LVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANST 496
+P P W KG + ++ ++ E+G+LEI ++ G YTC A N G A +
Sbjct: 472 FFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNE 531
Query: 497 GTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHY 556
L I DPT I+ P A + G + +C D L LT +W + N+E +
Sbjct: 532 VHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW------LKDNRE-LPS 584
Query: 557 QRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIR 616
F +D + L++ + +G YTC A T +D+ SASA L V P PP L + D
Sbjct: 585 DERFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDLELTDQL 643
Query: 617 ATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPI------IEGNMEAARAVD 670
SV L+W+ G DN+SPI+K+ I +++DA P + + G A+ +
Sbjct: 644 DKSVQLSWTPGDDNNSPITKFII--------EYEDAMHKPGLWHHQTEVSGTQTTAQ-LK 694
Query: 671 LIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPL 730
L P++ Y FRV+A N++G+ PS S + T + P+ P+ V G G L ITW PL
Sbjct: 695 LSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPL 754
Query: 731 SREYHYGNNFGYIVAFKPFDG-EEWKKVTVTNPDTGRY-VHKDETMSPSTAFQVKVKAFN 788
+ G Y V+++ DG +EW V V N +Y V T P + +KV+A N
Sbjct: 755 NGFESNGPGLQYKVSWRQKDGDDEWTSVVVAN--VSKYIVSGTPTFVP---YLIKVQALN 809
Query: 789 NKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIV----ESYQIRY 844
+ G P V + +S +D P AP V V V++S+ VHW+ V K + + Y+I Y
Sbjct: 810 DMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYY 869
Query: 845 WAAHDKEEAANR------VQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEA 898
W + R + + L L P + Y + V N G GP S
Sbjct: 870 WKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVF 929
Query: 899 FTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRP 946
T + PS P + + + WD +T Y + Y+P
Sbjct: 930 NTPEGVPSAPSSLKIVNPTLDSLTLEWD--PPSHPNGILTEYTLKYQP 975
Score = 79.3 bits (194), Expect = 2e-14
Identities = 95/396 (23%), Positives = 160/396 (40%), Gaps = 40/396 (10%)
Query: 45 EQPINTIYPE------ESLEGKV-SLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGN 97
E+P + PE E L G V SL C A P P+ W +G + Y
Sbjct: 259 ERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT 318
Query: 98 LVINNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLL 157
L I + + D+G Y C+A N G + T + P+ + + G+ L+
Sbjct: 319 LQIIHV-SEADSGNYQCIAKNALGAIHHTISVRV--KAAPYWITAPQNLVLSPGEDGTLI 375
Query: 158 CDPPYHFPDDLSYRWLLNEFPVFITMD--KRRFVSQTNGNLYIANVEASDKGNYSCFVSS 215
C + +S WL N P+ I D R+ T + +NV+ Y C S+
Sbjct: 376 CRANGNPKPRIS--WLTNGVPIEIAPDDPSRKIDGDT---IIFSNVQERSSAVYQCNASN 430
Query: 216 PSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRW 275
+ + F+ ++ P R PA+ + Q + + L+C G+P+P I W
Sbjct: 431 -EYGYLLANAFVNVLAEPPRILT--PANTLYQ-----VIANRPALLDCAFFGSPLPTIEW 482
Query: 276 RKVLEPMPSTAEIST--SGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEW 333
K + +I L+I Q + G Y C A N G K++ + ++ P W
Sbjct: 483 FKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD-PTW 541
Query: 334 -VEHINDTEVDIGSDLYWPCVATGKPI--PTIRWLKNG--------YAYHKGELRLYDVT 382
V+ V GS + + C T+ WLK+ + K L + DV+
Sbjct: 542 IVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVS 601
Query: 383 FENAGMYQCIAENTYGAIYANAELKILALA-PTFEM 417
+++G Y C+A T ++ A+A L ++ + P F++
Sbjct: 602 DDDSGTYTCVANTTLDSVSASAVLSVVDVPNPPFDL 637
Score = 73.2 bits (178), Expect = 1e-12
Identities = 95/427 (22%), Positives = 164/427 (38%), Gaps = 73/427 (17%)
Query: 233 PERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK-----VLEPMPSTAE 287
P T+ P D ++ ++ N+ ++C A G P P W + ++ P
Sbjct: 39 PPTITQQSPKDYIIDPRE-------NIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM 91
Query: 288 ISTSGAVLKIFNIQLED-----EGIYECEAENIRGKD-KHQARIYVQAFPEWV-EHINDT 340
+G + I NI E EG+Y+C A N RG + + P W E +
Sbjct: 92 KPGTGTL--IINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPI 149
Query: 341 EVDIGSDLYWPC-VATGKPIPTIRWLKNGYAYHKGELRLY-----DVTFENA------GM 388
+ G L PC G P P I W+ N + R+ D+ F N
Sbjct: 150 TLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTRED 209
Query: 389 YQCIAENTYGAIYANAE---LKILAL-------------------------APTF---EM 417
Y C A + + +K++++ PTF E
Sbjct: 210 YICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEG 269
Query: 418 NPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRN 477
N K+ L +G + +EC + P P W+K L + + + +L+I +++
Sbjct: 270 NASNKEEL--RGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEA 327
Query: 478 DGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLT 537
D G Y C A+N G + T ++ + I AP N ++ GE+ T+ C A+ +P ++
Sbjct: 328 DSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRIS 387
Query: 538 FVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASAD 597
W NG I+ ++ + +D + ++ N Q + + Y C A A+A
Sbjct: 388 --WLTNGVPIEIAPDD----PSRKIDGD-TIIFSNVQERSSAVYQCNASNEYGYLLANAF 440
Query: 598 LVVRGPP 604
+ V P
Sbjct: 441 VNVLAEP 447
Score = 43.9 bits (102), Expect = 8e-04
Identities = 29/99 (29%), Positives = 48/99 (48%), Gaps = 8/99 (8%)
Query: 409 LALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSK-GTEWLVNSSRILIWE-- 465
L PT K I+ + ++I+C+ K P P FSW++ GT + ++ ++ +
Sbjct: 36 LVQPPTITQQSPKDYIIDPREN-IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPG 94
Query: 466 DGSLEINNITRNDG----GIYTCFAENNRGKANSTGTLV 500
G+L IN ++ G+Y C A N RG A S +V
Sbjct: 95 TGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 133
>gi|81158226 neuronal cell adhesion molecule isoform A precursor
[Homo sapiens]
Length = 1304
Score = 308 bits (789), Expect = 2e-83
Identities = 262/958 (27%), Positives = 413/958 (43%), Gaps = 102/958 (10%)
Query: 61 VSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVG---GNLVINNPDKQKDA---GIYYC 114
+ + C A+ P P + W N D+ D + G L+IN + K G+Y C
Sbjct: 64 IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGVYQC 123
Query: 115 LASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLL 174
A N G S + + E+ + ++ G+ +VL C PP P + + W+
Sbjct: 124 TARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIF-WMD 182
Query: 175 NEFPVFITMDKRRFVSQ-TNGNLYIANVEASD-KGNYSCFVSSPSITKSVFSK---FIPL 229
N F + + VSQ NG+LY +NV D + +Y C+ + T+++ K + +
Sbjct: 183 NSFQ---RLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARF-NHTQTIQQKQPISVKV 238
Query: 230 IPIPE-----------------RTTKPYPADIVV---QFKDVYALMGQNVTLECFALGNP 269
I + E ++++ P + + L G ++LEC A G P
Sbjct: 239 ISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLP 298
Query: 270 VPDIRWRKVLEPMPSTAEISTS-GAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQ 328
P I W K +P + + L+I ++ D G Y+C A+N G H + V+
Sbjct: 299 TPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVK 358
Query: 329 AFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYH----------KGELRL 378
A P W+ + + G D C A G P P I WL NG G+ +
Sbjct: 359 AAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTII 418
Query: 379 Y-DVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECK 437
+ +V ++ +YQC A N YG + ANA + +LA P + P +++C
Sbjct: 419 FSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPPRI-LTPANTLYQVIANRPALLDCA 477
Query: 438 PKAAPKPKFSWSKGTEW-LVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANST 496
+P P W KG + ++ ++ E+G+LEI ++ G YTC A N G A +
Sbjct: 478 FFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNE 537
Query: 497 GTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHY 556
L I DPT I+ P A + G + +C D L LT +W + N+E +
Sbjct: 538 VHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLW------LKDNRE-LPS 590
Query: 557 QRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGP----------PGP 606
F +D + L++ + +G YTC A T +D+ SASA L V P P P
Sbjct: 591 DERFTVDKD-HLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAPTPTPAPVYDVPNP 649
Query: 607 PGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPI------IE 660
P L + D SV L+W+ G DN+SPI+K+ I+ ++DA P + +
Sbjct: 650 PFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIE--------YEDAMHKPGLWHHQTEVS 701
Query: 661 GNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRN 720
G A+ + L P++ Y FRV+A N++G+ PS S + T + P+ P+ V G G
Sbjct: 702 GTQTTAQ-LKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEP 760
Query: 721 RELTITWAPLSREYHYGNNFGYIVAFKPFDG-EEWKKVTVTNPDTGRY-VHKDETMSPST 778
L ITW PL+ G Y V+++ DG +EW V V N +Y V T P
Sbjct: 761 DNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVAN--VSKYIVSGTPTFVP-- 816
Query: 779 AFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIV- 837
+ +KV+A N+ G P V + +S +D P AP V V V++S+ VHW+ V K +
Sbjct: 817 -YLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIR 875
Query: 838 ---ESYQIRYWAAHDKEEAANR------VQVTSQEYSARLENLLPDTQYFIEVGACNSAG 888
+ Y+I YW + R + + L L P + Y + V N G
Sbjct: 876 GHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKG 935
Query: 889 CGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRP 946
GP S T + PS P + + + WD +T Y + Y+P
Sbjct: 936 EGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWD--PPSHPNGILTEYTLKYQP 991
Score = 83.6 bits (205), Expect = 9e-16
Identities = 96/392 (24%), Positives = 158/392 (40%), Gaps = 39/392 (9%)
Query: 45 EQPINTIYPE------ESLEGKV-SLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGN 97
E+P + PE E L G V SL C A P P+ W +G + Y
Sbjct: 265 ERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT 324
Query: 98 LVINNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLL 157
L I + + D+G Y C+A N G + T + P+ + + G+ L+
Sbjct: 325 LQIIHV-SEADSGNYQCIAKNALGAIHHTISVRV--KAAPYWITAPQNLVLSPGEDGTLI 381
Query: 158 CDPPYHFPDDLSYRWLLNEFPVFITMD--KRRFVSQTNGNLYIANVEASDKGNYSCFVSS 215
C + +S WL N P+ I D R+ T + +NV+ Y C S+
Sbjct: 382 CRANGNPKPRIS--WLTNGVPIEIAPDDPSRKIDGDT---IIFSNVQERSSAVYQCNASN 436
Query: 216 PSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRW 275
+ + F+ ++ P R PA+ + Q + + L+C G+P+P I W
Sbjct: 437 -EYGYLLANAFVNVLAEPPRILT--PANTLYQ-----VIANRPALLDCAFFGSPLPTIEW 488
Query: 276 RKVLEPMPSTAEIST--SGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEW 333
K + +I L+I Q + G Y C A N G K++ + ++ P W
Sbjct: 489 FKGAKGSALHEDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKD-PTW 547
Query: 334 -VEHINDTEVDIGSDLYWPCVATGKPI--PTIRWLKNG--------YAYHKGELRLYDVT 382
V+ V GS + + C T+ WLK+ + K L + DV+
Sbjct: 548 IVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDHLVVADVS 607
Query: 383 FENAGMYQCIAENTYGAIYANAELKILALAPT 414
+++G Y C+A T ++ A+A L ++A PT
Sbjct: 608 DDDSGTYTCVANTTLDSVSASAVLSVVAPTPT 639
Score = 73.2 bits (178), Expect = 1e-12
Identities = 95/427 (22%), Positives = 164/427 (38%), Gaps = 73/427 (17%)
Query: 233 PERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK-----VLEPMPSTAE 287
P T+ P D ++ ++ N+ ++C A G P P W + ++ P
Sbjct: 45 PPTITQQSPKDYIIDPRE-------NIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM 97
Query: 288 ISTSGAVLKIFNIQLED-----EGIYECEAENIRGKD-KHQARIYVQAFPEWV-EHINDT 340
+G + I NI E EG+Y+C A N RG + + P W E +
Sbjct: 98 KPGTGTL--IINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPI 155
Query: 341 EVDIGSDLYWPC-VATGKPIPTIRWLKNGYAYHKGELRLY-----DVTFENA------GM 388
+ G L PC G P P I W+ N + R+ D+ F N
Sbjct: 156 TLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTRED 215
Query: 389 YQCIAENTYGAIYANAE---LKILAL-------------------------APTF---EM 417
Y C A + + +K++++ PTF E
Sbjct: 216 YICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEG 275
Query: 418 NPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRN 477
N K+ L +G + +EC + P P W+K L + + + +L+I +++
Sbjct: 276 NASNKEEL--RGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEA 333
Query: 478 DGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLT 537
D G Y C A+N G + T ++ + I AP N ++ GE+ T+ C A+ +P ++
Sbjct: 334 DSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRIS 393
Query: 538 FVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASAD 597
W NG I+ ++ + +D + ++ N Q + + Y C A A+A
Sbjct: 394 --WLTNGVPIEIAPDD----PSRKIDGD-TIIFSNVQERSSAVYQCNASNEYGYLLANAF 446
Query: 598 LVVRGPP 604
+ V P
Sbjct: 447 VNVLAEP 453
Score = 44.7 bits (104), Expect = 5e-04
Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 8/102 (7%)
Query: 406 LKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSK-GTEWLVNSSRILIW 464
L+ L PT K I+ + ++I+C+ K P P FSW++ GT + ++ ++
Sbjct: 39 LEDLVQPPTITQQSPKDYIIDPREN-IVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTM 97
Query: 465 E--DGSLEINNITRNDG----GIYTCFAENNRGKANSTGTLV 500
+ G+L IN ++ G+Y C A N RG A S +V
Sbjct: 98 KPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 139
Score = 43.5 bits (101), Expect = 0.001
Identities = 76/347 (21%), Positives = 128/347 (36%), Gaps = 41/347 (11%)
Query: 581 YTCTAQTIVDNSSASADLVVRGPPGP------PGGLRIEDIRATSVALTWS-------RG 627
Y Q + D A VV G G PG +R+ + +T + W RG
Sbjct: 817 YLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRG 876
Query: 628 SDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTL 687
I Y +T++ + + + +G+ L P+ Y V N
Sbjct: 877 HLQGYRI--YYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGK 934
Query: 688 GRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFK 747
G G P+ P T P+ APS + LT+ W P S + G Y + ++
Sbjct: 935 GEG-PASPDRVFNTPEGVPS-APSSLKIVNPTLDSLTLEWDPPS--HPNGILTEYTLKYQ 990
Query: 748 PFDG--EEWKKVTVTNP-DTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSA 804
P + E V + P + R+ K+ ++ ST ++ A + G G + +
Sbjct: 991 PINSTHELGPLVDLKIPANKTRWTLKN--LNFSTRYKFYFYAQTSAGSGSQITEEAVTTV 1048
Query: 805 QDAPSEAPTEVGV--------------KVLSSSEISVHWEHVLEKIVESYQIRYWAAHDK 850
+A P +VG + + ++ WE+ + V Y + Y A K
Sbjct: 1049 DEA-GILPPDVGAGKVQAVNPRISNLTAAAAETYANISWEYEGPEHVNFY-VEYGVAGSK 1106
Query: 851 EEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIE 897
EE + S+ + L+ L+P T Y + VGA +G D+ E
Sbjct: 1107 EEWRKEIVNGSRSFFG-LKGLMPGTAYKVRVGAVGDSGFVSSEDVFE 1152
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 281 bits (718), Expect = 3e-75
Identities = 254/1003 (25%), Positives = 427/1003 (42%), Gaps = 87/1003 (8%)
Query: 41 PIFEEQPINTIYPEESLEG-KVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLV 99
P F+ +P P+ LEG ++ L C A S +KW ++ ++ S Y + +L
Sbjct: 104 PYFKTEPG---LPQIHLEGNRLVLTCLAEGSWPLEFKWMRDDSELTTYSSEYKYIIPSL- 159
Query: 100 INNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCD 159
++ DAG Y C+ N G + ++ + Y+ F ++ + V +G+ +L
Sbjct: 160 -----QKLDAGFYRCVVRNRMGALLQRKSEVQVAYMGSFMDTDQRKT-VSQGRAAILNLL 213
Query: 160 PPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSIT 219
P +P W + + R L I SD G Y +
Sbjct: 214 PITSYPRP-QVTWFREGHKI---IPSNRIAITLENQLVILATTTSDAGAYYVQAVNEKNG 269
Query: 220 KSVFSKFIPL-IPIPERTTKPYPADIVVQFKDVYALMGQN-VTLECFALGNPVPD--IRW 275
++ S FI L I T + IVV + + G + TLEC A PV D + W
Sbjct: 270 ENKTSPFIHLSIARDVGTPETMAPTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVTW 329
Query: 276 RKVLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARI---------- 325
++ + T+ + + G L I N D G Y CEA + G AR
Sbjct: 330 KR--NGVRITSGLHSFGRRLTISNPTSADTGPYVCEAA-LPGSAFEPARATAFLFIIEPP 386
Query: 326 YVQAFPEW-VEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHK----------- 373
Y A PE + + VDIG C A G P+PT++W K+ + +
Sbjct: 387 YFTAEPESRISAEVEETVDIG------CQAMGVPLPTLQWYKDAISISRLQNPRYKVLAS 440
Query: 374 GELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVI 433
G LR+ + E++G++QC A N G I + L + +AP F P+ + G I
Sbjct: 441 GGLRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRPVDTTV--TDGMTAI 498
Query: 434 IECKPKAAPKPKFSWSKGTEWLVNSS----RILIWEDGSLEINNITRNDGGIYTCFAENN 489
+ C+ APKP +W + L + S R ++ E G L+I + D G YTC+A N
Sbjct: 499 LRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANT 558
Query: 490 RGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDF 549
G N++ TL + + T I+ P + + G AT+ C A+ DP + L +VW + +
Sbjct: 559 EGSLNASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDPRVSLRYVWKKDNVALTP 618
Query: 550 NKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGG 609
+ + +++ +G LLI G Y+C + N S A L V P P
Sbjct: 619 SSTS-----RIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIELPHSPQN 673
Query: 610 LRI--EDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAAR 667
L + + +V L+W R D +SPI Y ++ LS++ K + M
Sbjct: 674 LLVSPNSSHSHAVVLSWVRPFDGNSPILYYIVE----LSENNSPWKVHLSNVGPEMTGVT 729
Query: 668 AVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITW 727
L P Y+FRV A N +GRG+ S ++R+ P+ P ++ G N+ + + W
Sbjct: 730 VSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQW 789
Query: 728 APLSREYHYGNNFGYIVAFKPFD-GEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKA 786
P H G GYI+ ++ E+++ +T+P+ + D + T ++++V A
Sbjct: 790 QPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCLVTD--LIIWTQYEIQVAA 847
Query: 787 FNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHW----EHVLEKIVESYQI 842
+N G G +S + Q P+ P V + ++S+ I W + + I + Y++
Sbjct: 848 YNGAGLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKL 907
Query: 843 RYWAAHDKEEAANRVQVTSQ---EYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAF 899
W A D EA V + + + NL T YF V + G GPPS +
Sbjct: 908 LAWPA-DAPEAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVW 966
Query: 900 TKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQHDGKL----- 954
T++ P + + + ++W L +TGY++ + G++D +L
Sbjct: 967 TQEDKPGAVGHLSFTEILDTSLKVSWQE--PLEKNGIITGYQISWEVYGRNDSRLTHTLN 1024
Query: 955 YSTHKHSIEVPIPRDGEYVVEVRAHSDGGDGVVSQVKI-SGAP 996
+TH++ I+ + Y ++V A + G G+V+ I SG P
Sbjct: 1025 STTHEYKIQ-GLSSLTTYTIDVAAVTAVGTGLVTSSTISSGVP 1066
Score = 120 bits (300), Expect = 8e-27
Identities = 95/373 (25%), Positives = 159/373 (42%), Gaps = 32/373 (8%)
Query: 601 RGPPGPPGGLRIE--DIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPI 658
R P PP L + ++ A S+ L W GSD SPI +T+Q + + +W+ +
Sbjct: 1474 RERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSS--- 1530
Query: 659 IEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGG 718
I A L P+ Y+ R+ ATN +G + S + + T P P V
Sbjct: 1531 ISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPH 1590
Query: 719 RNRELTITWAPLSREYHYGNNFGYIVAFKPFD---GEEWKKVTVTNP----------DTG 765
+ I W P E G GY + ++ + G + T+ NP +
Sbjct: 1591 TTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSF 1650
Query: 766 RYVHKDET--------MSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGV 817
+ V+ T + ++V + A+N G+ P S + + AP+ AP V V
Sbjct: 1651 KTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQV 1710
Query: 818 KVLSSSEISVHWEHVLEKI----VESYQIRYWAAHDKEEAANRVQVTSQEYSARLENLLP 873
L++S++ V W+ + ++ Y+I YW A + E + E RL+NL
Sbjct: 1711 TPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTS 1770
Query: 874 DTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSN 933
T+Y + + A N+AG GP SD + T +A P P + S + + ++W A +
Sbjct: 1771 HTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAAN- 1829
Query: 934 ESTVTGYKVLYRP 946
+ GY+V+Y P
Sbjct: 1830 -GILQGYRVVYEP 1841
Score = 92.0 bits (227), Expect = 2e-18
Identities = 85/359 (23%), Positives = 153/359 (42%), Gaps = 30/359 (8%)
Query: 604 PGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNM 663
PG G L +I TS+ ++W + + I+ Y I + +D + T +
Sbjct: 972 PGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLTHT----LNSTT 1027
Query: 664 EAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNV--APSDVGGGGGRNR 721
+ L Y V A +G G + ++ + G P++ APS++ R
Sbjct: 1028 HEYKIQGLSSLTTYTIDVAAVTAVGTG---LVTSSTISSGVPPDLPGAPSNLVISNISPR 1084
Query: 722 ELTITWAP-------LSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETM 774
T+ + P +SR G G I D EEW + + + + +
Sbjct: 1085 SATLQFRPGYDGKTSISRWIVEGQ-VGAIG-----DEEEWVTLYEEENEPDAQMLEIPNL 1138
Query: 775 SPSTAFQVKVKAFNNKGDGPYSLVA-VINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVL 833
+P T ++ ++K N G PYS + VI + Q P APT V V+ S + + + W +
Sbjct: 1139 TPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLP 1198
Query: 834 EKIVES------YQIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSA 887
+ Y+I+YW + + A +V E +E L +Y +++ A N+
Sbjct: 1199 DSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQAFNAV 1258
Query: 888 GCGPPSDMIEAFTKKAPPSQPPRIISS-VRSGSRYIITWDHVVALSNESTVTGYKVLYR 945
G GP S+++ T+++ PS P +S+ S ++ ++TW V + GYK+L+R
Sbjct: 1259 GAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFR 1317
Score = 85.9 bits (211), Expect = 2e-16
Identities = 102/445 (22%), Positives = 172/445 (38%), Gaps = 56/445 (12%)
Query: 585 AQTIVDNSSASADLVVR----GPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQ 640
A T + N S L++ PGPP L ++R TSV + W + + I Y I
Sbjct: 1355 AFTRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIA 1414
Query: 641 TKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIK 700
+ S + + + A DL P Y FR+ A G GEP + + I
Sbjct: 1415 YRLASSSPHTFTTVE---VGATVRQFTATDLAPESAYIFRLSAKTRQGWGEP-LEATVIT 1470
Query: 701 TDGAAPNVAPSD--VGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVT 758
T+ P + V R L + W P S F V P + +
Sbjct: 1471 TEKRERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSS 1530
Query: 759 VTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSL-VAVINSAQDAPSEAPTEVGV 817
+++ T V + + P T++++++KA N+ GD +S + + QD P E P V
Sbjct: 1531 ISHEATACVV---DRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSA 1587
Query: 818 KVLSSSEISVHW----EHVLEKIVESYQIRY----------------------WAAHDKE 851
++S + + W + L +++ Y+I Y A +
Sbjct: 1588 TPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQ 1647
Query: 852 EAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRI 911
+ V +S L +L +Y + + A N G P S +E F +A P+ P+
Sbjct: 1648 SSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQN 1707
Query: 912 IS-SVRSGSRYIITWDHVVALSNESTVTGYKVLY-RPDGQHDGKLYSTHKHSI---EVPI 966
+ + + S+ +TWD S + GYK+ Y D Q++ T K + P+
Sbjct: 1708 VQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNE-----TEKMKVLFLPEPV 1762
Query: 967 PR------DGEYVVEVRAHSDGGDG 985
R +Y+V + A + GDG
Sbjct: 1763 VRLKNLTSHTKYLVSISAFNAAGDG 1787
Score = 70.5 bits (171), Expect = 8e-12
Identities = 57/245 (23%), Positives = 98/245 (40%), Gaps = 8/245 (3%)
Query: 670 DLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAP 729
+L WMEYE ++ A N +G G P R +T + P+ AP +V + ++ +TW
Sbjct: 1241 ELEEWMEYELQMQAFNAVGAG-PWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTS 1299
Query: 730 LSREYHYGNNFGYIVAF--KPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAF 787
+ + G GY + F K D E + N + + ++++V AF
Sbjct: 1300 VPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSALL---AGLRKFVLYELQVLAF 1356
Query: 788 NNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEK--IVESYQIRYW 845
G+G S ++ +D P + + + + + W+ E I+ YQI Y
Sbjct: 1357 TRIGNGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYR 1416
Query: 846 AAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPP 905
A V+V + +L P++ Y + A G G P + T+K
Sbjct: 1417 LASSSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRER 1476
Query: 906 SQPPR 910
PPR
Sbjct: 1477 PAPPR 1481
Score = 64.7 bits (156), Expect = 4e-10
Identities = 92/365 (25%), Positives = 143/365 (39%), Gaps = 29/365 (7%)
Query: 599 VVRG------PPGPPGGLRIEDIRATSVALTWSR--GSDNHSPISKYTIQTKTILSDDWK 650
VVRG P P + E + +T + LTW+ D + I Y I + K
Sbjct: 1266 VVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRA------K 1319
Query: 651 DAKTDPP--IIEGN-MEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPN 707
D +P I+ GN ++A L ++ YE +V+A +G G PS P +T AP
Sbjct: 1320 DLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPG 1379
Query: 708 VAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRY 767
P + R + I W P E G GY +A++ TV T R
Sbjct: 1380 -PPVRLVFPEVRLTSVRIVWQP--PEEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQ 1436
Query: 768 VHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISV 827
+ ++P +A+ ++ A +G G VI + + P E+ V + S+
Sbjct: 1437 FTATD-LAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSL 1495
Query: 828 HWEHVLEKIVESYQIRYWAAHDKEEAANRVQVTSQEYSAR-----LENLLPDTQYFIEVG 882
+ V S IRY+ +E Q S S ++ L P T Y + +
Sbjct: 1496 RLQWVPGSDGAS-PIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLK 1554
Query: 883 ACNSAGCGPPSDMIEAFTK-KAPPSQPPRIISSV-RSGSRYIITWDHVVALSNESTVTGY 940
A N G S EA T + P +PP +S+ + S +I W S + GY
Sbjct: 1555 ATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGY 1614
Query: 941 KVLYR 945
++ YR
Sbjct: 1615 RIYYR 1619
Score = 48.5 bits (114), Expect = 3e-05
Identities = 37/125 (29%), Positives = 52/125 (41%), Gaps = 5/125 (4%)
Query: 585 AQTIVDNSSASADLVVRGPPGPPGGLR--IEDIRATSVALTWSRGSDNHSPISKYTIQTK 642
A+TI A++ G PG R + A+ + L W+ G +P + Y I+ +
Sbjct: 1881 ARTITYGPELQANITAGPAEGSPGSPRDVLVTKSASELTLQWTEGHSGDTPTTGYVIEAR 1940
Query: 643 TILSDDWKDAKTDPPIIEGNMEAARAVD-LIPWMEYEFRVVATNTLGRGEPSIPSNRIKT 701
W D P ++D L + YEFRVVA N G GEPS PS +
Sbjct: 1941 PSDEGLWDMFVKDIP--RSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSA 1998
Query: 702 DGAAP 706
AP
Sbjct: 1999 QVEAP 2003
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 245 bits (625), Expect = 2e-64
Identities = 252/1017 (24%), Positives = 414/1017 (40%), Gaps = 106/1017 (10%)
Query: 41 PIFEEQPINTIYPEESLEG-KVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLV 99
P F+ +P+ T + LEG ++ L C A S +KW NN ++ S Y +
Sbjct: 26 PYFKTEPVRT---QVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEY-----RYM 77
Query: 100 INNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCD 159
I + D+ AG Y C+ N G + + + Y+ F E+ + V G+ V+
Sbjct: 78 ITSLDRTH-AGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQ-SVSHGEAAVIRAP 135
Query: 160 PPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSIT 219
FP W + + R L I + A D G Y +
Sbjct: 136 RIASFPQP-QVTWFRDGRKI---PPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNG 191
Query: 220 KSVFSKFIPL-IPIPERTTKPYPADIVVQFKDVYALMGQN-VTLECFALGNPVPDIR--W 275
+ S+ I L + P I++ K+ + G + VTLEC A P+ + W
Sbjct: 192 DNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIW 251
Query: 276 RKVLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEA--------ENIRGKDKHQARIYV 327
+K + + + IS L I N D G YECEA +RG A + V
Sbjct: 252 KK--DGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRG-----AYLSV 304
Query: 328 QAFPEWVE----HINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAY-----------H 372
P++V+ HI E++ D+ PC A G P P+I W K+ +
Sbjct: 305 LEPPQFVKEPERHIT-AEMEKVVDI--PCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRN 361
Query: 373 KGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRV 432
G L++ + ++ GM+QC A N G + + L + ++AP P+ ++ G V
Sbjct: 362 DGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVI--DGMSV 419
Query: 433 IIECKPKAAPKPKFSWSKGTEWLVNSS----RILIWEDGSLEINNITRNDGGIYTCFAEN 488
++ C+ AP+P +W KG L + S R E GSL I+ +D G YTC A N
Sbjct: 420 VLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATN 479
Query: 489 NRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVID 548
+RG ++ LV+ TRI P + + G A+M C + DP + + ++W +G +
Sbjct: 480 SRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATL- 538
Query: 549 FNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPG 608
LD NG L I G YTC + N S SA L VR P P
Sbjct: 539 ----GTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPE 594
Query: 609 G--LRIEDIRATSVALTWSRGSDNHSPISKYTIQTK------TILSDDWKDAKTDPPIIE 660
+ + ++ LTW++ D +SP+ +Y ++ T+L A DP
Sbjct: 595 HPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLL-----ASVDPKATS 649
Query: 661 GNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRN 720
++ L+P Y+FR+ A N +G+G+ S + R+ P P +V G N
Sbjct: 650 VTVKG-----LVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTN 704
Query: 721 RELTITWAPLSREYHYGNNFGYIVAF----KPFDGEEWKKVTVTNPDTGRYVHKDETMSP 776
+ + I W P + G GYI+ + P G ++K +T+ D + +D +
Sbjct: 705 QSIMIQWQPPPESHQNGILKGYIIRYCLAGLPV-GYQFK--NITDADVNNLLLED--LII 759
Query: 777 STAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWE----HV 832
T ++++V A+N+ G G YS + Q P+ P V + +S+ I W
Sbjct: 760 WTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQF 819
Query: 833 LEKIVESYQIRYWAAHDKEE---AANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGC 889
+ I + Y++ W +EE R + + L T+YF V + G
Sbjct: 820 INGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGD 879
Query: 890 GPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQ 949
GP S T + P + S + ++W +TGY++ + +
Sbjct: 880 GPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQE--PGEKNGILTGYRISWEEYNR 937
Query: 950 HDGKLYSTHKHSIEVPIPRDG-----EYVVEVRAHSDGGDGVVSQVKI-SGAPTLSP 1000
+ ++ + + ++ + G Y +EV A + G G VS I SG P P
Sbjct: 938 TNTRV-THYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELP 993
Score = 132 bits (333), Expect = 1e-30
Identities = 107/404 (26%), Positives = 177/404 (43%), Gaps = 39/404 (9%)
Query: 581 YTCTAQTIVDNSSASADLVV----RGPPGPPGGLRI--EDIRATSVALTWSRGSDNHSPI 634
+ TAQT A+ LVV R P PP + ED+RA SV L+W GSD SP+
Sbjct: 1373 FRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPV 1432
Query: 635 SKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSI 694
YTIQT+ + S W + N + L P+ Y+FRV ATN +G E S
Sbjct: 1433 RYYTIQTRELPSGRW---ALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSE 1489
Query: 695 PSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPF----- 749
S + T AAP+ AP+ + + I W P + + G G+ + ++
Sbjct: 1490 ESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGL 1549
Query: 750 ----------DGEEWKKVT-------VTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGD 792
G W ++T ++ P +Y + + ++ +++++ +N G+
Sbjct: 1550 RGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQY--ELDNLNKHRRYEIRMSVYNAVGE 1607
Query: 793 GPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWE----HVLEKIVESYQIRYWAAH 848
GP S + + P+ AP V V +++++ V WE ++ Y+I +W A
Sbjct: 1608 GPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQ 1667
Query: 849 DKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQP 908
+ E S +L+NL T Y + V A N+AG GP S + T++A PS P
Sbjct: 1668 RGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAP 1727
Query: 909 PRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQHDG 952
+ S + + ++W+ + GY+++Y P DG
Sbjct: 1728 SSVKFSELTTTSVNVSWE--APQFPNGILEGYRLVYEPCSPVDG 1769
Score = 108 bits (269), Expect = 3e-23
Identities = 98/362 (27%), Positives = 154/362 (42%), Gaps = 23/362 (6%)
Query: 548 DFNKENI---HYQRNFMLDSNGELLIRNAQLKHAGRYTC--TAQTIVDNSSASADLVVRG 602
++N+ N HY N L+ R L YT A T SA + G
Sbjct: 934 EYNRTNTRVTHYLPNVTLE------YRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSG 987
Query: 603 PP----GPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPI 658
P GPP L I +I SV L + G D + IS++ ++ + + + ++ +
Sbjct: 988 VPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQL 1047
Query: 659 I-EGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGG 717
E + + DL P+ Y FR+ N +G PS PS +I+T A P++AP++V
Sbjct: 1048 SNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRT 1107
Query: 718 GRNRELTITWAPLSREYHYGN--NFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMS 775
L + W PL + GN + GY + + DG K ++ D + E +
Sbjct: 1108 ASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDG-HGKTLSHVVQDRVERDYTIEDLE 1166
Query: 776 PSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEK 835
T ++V+V+AFN G GP+S V + + PS PT V +SS + V W V E
Sbjct: 1167 EWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEA 1226
Query: 836 ----IVESYQIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGP 891
+V Y++ Y + + + SA+L L Y ++V A G G
Sbjct: 1227 DRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGS 1286
Query: 892 PS 893
PS
Sbjct: 1287 PS 1288
Score = 85.9 bits (211), Expect = 2e-16
Identities = 116/491 (23%), Positives = 199/491 (40%), Gaps = 64/491 (13%)
Query: 544 GYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIV------DNSSASAD 597
GY + + +++ Q F L R+AQL G+Y ++ D S +
Sbjct: 1234 GYKVMYKEKDSDTQPRFWLVEGNSS--RSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPP 1291
Query: 598 LVVR---GPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKT 654
++ R PGPP G+ ++R TSV L W + + I Y I T + + A
Sbjct: 1292 ILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQI-THRLNTTTANTATV 1350
Query: 655 DPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGE--PSIPSNRIKTDGAAPNVAPSD 712
+ ++ + A L P Y FR+ A G GE ++ K D P P
Sbjct: 1351 E--VLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPM- 1407
Query: 713 VGGGGGRNRELTITWAPLS---REYHYGNNFGYIVAFKPFDGEEW--KKVTVTNPDTGRY 767
V R R + ++W P S Y Y + + W +V++ +
Sbjct: 1408 VQQEDVRARSVLLSWEPGSDGLSPVRY-----YTIQTRELPSGRWALHSASVSHNASSFI 1462
Query: 768 VHKDETMSPSTAFQVKVKAFNNKGDGPYSLVA-VINSAQDAPSEAPTEVGVKVLSSSEIS 826
V + + P T+++ +VKA N+ GD +S + + + Q AP EAPT + V +++ +
Sbjct: 1463 V---DRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVL 1519
Query: 827 VHW----EHVLEKIVESYQIRY-----------WAAHDKEEAANRVQVTSQEYSAR---- 867
+ W E + I+ ++IRY A ++TS YS R
Sbjct: 1520 IRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSM-YSMRNLSR 1578
Query: 868 -------LENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPR-IISSVRSGS 919
L+NL +Y I + N+ G GP S E F +A P+ PR ++ + +
Sbjct: 1579 PSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATAT 1638
Query: 920 RYIITWDHVVALSNESTVTGYKVLY----RPDGQHDGKLYSTHKHSIEVP-IPRDGEYVV 974
+ +TW+ S + GYK+ + R + K ++S+++ + Y+V
Sbjct: 1639 QLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMV 1698
Query: 975 EVRAHSDGGDG 985
V A + GDG
Sbjct: 1699 SVAAFNAAGDG 1709
Score = 84.0 bits (206), Expect = 7e-16
Identities = 100/443 (22%), Positives = 179/443 (40%), Gaps = 62/443 (13%)
Query: 604 PGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNM 663
PGP G L +I TS+ ++W + + ++ Y I W+ E N
Sbjct: 895 PGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRIS--------WE---------EYNR 937
Query: 664 EAARAVDLIPWMEYEFRVVATNTL-----------GRGEPSIPSNRIKTDGAAPNVA--P 710
R +P + E+RV L +G+ + ++ I + G P + P
Sbjct: 938 TNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISS-GVPPELPGPP 996
Query: 711 SDVGGGGGRNRELTITWAP-------LSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPD 763
+++G R +T+ + P +SR + G + +GEEW + + +
Sbjct: 997 TNLGISNIGPRSVTLQFRPGYDGKTSISR-WLVEAQVGVVG-----EGEEWLLIHQLSNE 1050
Query: 764 TGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVA-VINSAQDAPSEAPTEVGVKVLSS 822
+ ++P T + +++ N G P S + I + Q P AP V ++ S
Sbjct: 1051 PDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASE 1110
Query: 823 SEISVHWEHVLEKIVES------YQIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQ 876
+ + + W + E Y+I+Y + + + V E +E+L T+
Sbjct: 1111 TSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTE 1170
Query: 877 YFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSV-RSGSRYIITWDHVVALSNES 935
Y ++V A N+ G GP S + T+++ PS P +S++ + S ++ W V
Sbjct: 1171 YRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNG 1230
Query: 936 TVTGYKVLYR-PDGQHDGKLYSTHKHSI-EVPIPRDGEYV---VEVRAHSDGGDGVVSQV 990
V GYKV+Y+ D + + +S + G+YV V+V A + GDG S
Sbjct: 1231 LVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSH- 1289
Query: 991 KISGAPTLSPSLLGLLLPAFGIL 1013
P L +L + P GIL
Sbjct: 1290 ----PPILERTLDDVPGPPMGIL 1308
Score = 55.8 bits (133), Expect = 2e-07
Identities = 38/130 (29%), Positives = 59/130 (45%), Gaps = 5/130 (3%)
Query: 580 RYTCTAQTIVDNSSASADLVV---RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISK 636
R+ A+T A++ G PGPPG + I ++++A+ WS G PI++
Sbjct: 1798 RFRIRAKTFTYGPEIEANVTTGPGEGAPGPPG-VPIIVRYSSAIAIHWSSGDPGKGPITR 1856
Query: 637 YTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPS 696
Y I+ + W D P + + + L P + Y+FRV+A N G G PS PS
Sbjct: 1857 YVIEARPSDEGLWDILIKDIPKEVSSYTFSMDI-LKPGVSYDFRVIAVNDYGFGTPSSPS 1915
Query: 697 NRIKTDGAAP 706
+ A P
Sbjct: 1916 QSVPAQKANP 1925
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 225 bits (574), Expect = 1e-58
Identities = 234/944 (24%), Positives = 392/944 (41%), Gaps = 92/944 (9%)
Query: 37 KGFGPIFEEQPIN-TIYPEE---SLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYS 92
K G ++ +QP+ TI P + S+ +VSL+C + W NG++
Sbjct: 303 KVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSW-YRNGEILNPGKNVR 361
Query: 93 MVG---GNLVINNPDKQKDAGIYYC------LASNNYGMVRSTEATLSFGYLDPFPPEER 143
+ G NL++++ K D G Y C L++ +Y V + T P
Sbjct: 362 ITGINHENLIMDHMVKS-DGGAYQCFVRKDKLSAQDYVQVVLEDGT-------PKIISAF 413
Query: 144 PEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQ---TNGN----L 196
E V + + L+C+ ++ W L++ P+ R +SQ + GN L
Sbjct: 414 SEKVVSPAEPVSLMCNVKGTPLPTIT--WTLDDDPILKGGSHR--ISQMITSEGNVVSYL 469
Query: 197 YIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMG 256
I++ + D G Y C ++ + ++ R PA I K++ A+ G
Sbjct: 470 NISSSQVRDGGVYRCTANNSA----------GVVLYQARINVRGPASIR-PMKNITAIAG 518
Query: 257 QNVTLECFALGNPVPDIRWRKV--LEPMPSTAEISTSGAVLKIFNIQLE-DEGIYECEAE 313
++ + C +G P I+W K L P + LK+ ++Q E DEG Y C
Sbjct: 519 RDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVL 578
Query: 314 NIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIP-TIRWLKNGYAY- 371
Q+ P +++ IG ++ PCV +P TI W K+G
Sbjct: 579 VQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIP 638
Query: 372 -----------HKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPM 420
LR+ +++ + G Y CIA N A+ ++L I+ + P F + P
Sbjct: 639 GSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQL-IVRVPPKFVVQPR 697
Query: 421 KKKILAAKGGRVIIECKPKAAPKPKFSW--SKGT-----EWLVNSSRILIWEDGSLEINN 473
+ + K VI+ C + P P W SKG + + + RI + +GSL I +
Sbjct: 698 DQDGIYGKA--VILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKH 755
Query: 474 ITRNDGGIYTCFAENNRGKANSTGT-LVITDPTRIILAPINADITVGENATMQCAASFDP 532
+ D G Y C N+ G S L + P I P T G+ M C A +
Sbjct: 756 VVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEK 815
Query: 533 ALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQL-----KHAGRYTCTAQT 587
+ + W +I N E Y + GE +I Q+ + +G ++C A
Sbjct: 816 PIIVR--WEKEDRII--NPEMARYLVS--TKEVGEEVISTLQILPTVREDSGFFSCHAIN 869
Query: 588 IVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSD 647
L V+ PP PP + I+D++A ++ L W+ G D +SPI+ Y I+ K SD
Sbjct: 870 SYGEDRGIIQLTVQEPPDPPE-IEIKDVKARTITLRWTMGFDGNSPITGYDIECKN-KSD 927
Query: 648 DWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPN 707
W A+ + + +A +D+ P Y R+ A N +G+ EPS I D AAP+
Sbjct: 928 SWDSAQRTKDV-SPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELT-ITADEAAPD 985
Query: 708 VAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTG-- 765
P +V ++ + +TW + G GY + ++ + + + + DT
Sbjct: 986 GPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGD 1045
Query: 766 RYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEI 825
V+ + ++ T + + V+A N G GP S + + +D PS P V S I
Sbjct: 1046 SEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESI 1105
Query: 826 SVHW----EHVLEKIVESYQIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEV 881
S+ W + L I++ +++ YWA E +T+ + S L+ L T Y I+V
Sbjct: 1106 SISWSTLSKEALNGILQGFRVIYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQV 1165
Query: 882 GACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITW 925
A AG G S+ I TK+ P P + ++ S S ++W
Sbjct: 1166 LAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSW 1209
Score = 187 bits (476), Expect = 3e-47
Identities = 238/994 (23%), Positives = 388/994 (39%), Gaps = 120/994 (12%)
Query: 60 KVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLASNN 119
+V L C+A P P Y+W +N ++L+ V G L+ N + D+G Y C SN
Sbjct: 241 RVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIEN--IRPSDSGSYVCEVSNR 298
Query: 120 YGMVRSTEATLSFGYL-DPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFP 178
YG T + Y+ P P +VK G + +D W N
Sbjct: 299 YG----TAKVIGRLYVKQPLKATISPR-KVKSSVGSQVSLSCSVTGTEDQELSWYRNG-E 352
Query: 179 VFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTK 238
+ R + NL + ++ SD G Y CFV ++ + + + + + T K
Sbjct: 353 ILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVV----LEDGTPK 408
Query: 239 PYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPS------TAEISTSG 292
I+ F + + V+L C G P+P I W +P+ + I++ G
Sbjct: 409 -----IISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEG 463
Query: 293 AVLKIFNI---QLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLY 349
V+ NI Q+ D G+Y C A N G +QARI V+ P + + + G D Y
Sbjct: 464 NVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRG-PASIRPMKNITAIAGRDTY 522
Query: 350 WPCVATGKPIPTIRWLKNGYAY----------HKGELRLYDVTFE-NAGMYQC---IAEN 395
C G P +I+W KN + G L+L DV E + G Y C +
Sbjct: 523 IHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQ 582
Query: 396 TYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKP-KFSWSKGTEW 454
+ + +K+ FE + G RV I C + P +W K
Sbjct: 583 LSTSQSVHVTVKVPPFIQPFEFPRF------SIGQRVFIPCVVVSGDLPITITWQKDGRP 636
Query: 455 LVNSSRILIWE---DGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAP 511
+ S + I SL I+N++ G YTC A N L++ P + ++ P
Sbjct: 637 IPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP 696
Query: 512 INADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIR 571
+ D G+ + C+A P T VW F+ + I + SNG LLI+
Sbjct: 697 RDQDGIYGKAVILNCSAEGYPV--PTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIK 754
Query: 572 NAQLKHAGRYTCTAQTIVD-NSSASADLVVRGP-------------PGPPGGLRIEDIRA 617
+ + +G Y C V + S S L V+ P G +
Sbjct: 755 HVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGE 814
Query: 618 TSVALTWSRGSDNHSP-ISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWME 676
+ + W + +P +++Y + TK E E + ++P +
Sbjct: 815 KPIIVRWEKEDRIINPEMARYLVSTK-----------------EVGEEVISTLQILPTVR 857
Query: 677 YE---FRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSRE 733
+ F A N+ G + I ++ P + DV + R +T+ W
Sbjct: 858 EDSGFFSCHAINSYGE-DRGIIQLTVQEPPDPPEIEIKDV-----KARTITLRWT----M 907
Query: 734 YHYGNN--FGYIVAFKPFDGEEWKKVTVT---NPDTGRYVHKDETMSPSTAFQVKVKAFN 788
GN+ GY + K + W T +P D + PS+ + +++ A N
Sbjct: 908 GFDGNSPITGYDIECKN-KSDSWDSAQRTKDVSPQLNSATIID--IHPSSTYSIRMYAKN 964
Query: 789 NKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHW----EHVLEKIVESYQI-- 842
G S I + + AP P EV ++ +SS I V W +H+ I+ YQI
Sbjct: 965 RIGKSEPSNELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGY 1024
Query: 843 -RYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTK 901
Y + + V + L+NL TQY + V ACN AG GP S I T
Sbjct: 1025 REYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTL 1084
Query: 902 KAPPSQPPRIISSVRSGSRYI-ITWDHVVALSNESTVTGYKVLY---RPDGQ-HDGKLYS 956
+ PS PP + ++ + I I+W + + + G++V+Y DG+ + K +
Sbjct: 1085 EDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLMDGELGEIKNIT 1144
Query: 957 THKHSIEVP-IPRDGEYVVEVRAHSDGGDGVVSQ 989
T + S+E+ + + Y ++V A + GDGV S+
Sbjct: 1145 TTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSE 1178
Score = 158 bits (399), Expect = 3e-38
Identities = 216/918 (23%), Positives = 358/918 (38%), Gaps = 116/918 (12%)
Query: 61 VSLNCRARASPFPVYKWRMNNGDV-DLTSDRYSMV---GGNLV--INNPDKQ-KDAGIYY 113
VSL C + +P P W +++ + S R S + GN+V +N Q +D G+Y
Sbjct: 424 VSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYR 483
Query: 114 CLASNNYGMVRSTEATLSFGYLDPFPPEERP--EVRVKEGKGMVLLCDP---PYHFPDDL 168
C A+N+ G+V G P RP + G+ + C PY+
Sbjct: 484 CTANNSAGVVLYQARINVRG-----PASIRPMKNITAIAGRDTYIHCRVIGYPYY----- 533
Query: 169 SYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEAS-DKGNYSCFVS-SPSITKSVFSKF 226
S +W N + + R+ + NG L +++V+ D+G Y+C V P ++ S
Sbjct: 534 SIKWYKNSN--LLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHV 591
Query: 227 IPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVP-DIRWRKVLEPMPST 285
+P + F+ +GQ V + C + +P I W+K P+P +
Sbjct: 592 TVKVP-----------PFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGS 640
Query: 286 AEISTSG----AVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTE 341
++ + L+I N+ L G Y C A N +HQ+++ V+ P++V D +
Sbjct: 641 LGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQPRDQD 700
Query: 342 VDIGSDLYWPCVATGKPIPTIRW--------------LKNG--YAYHKGELRLYDVTFEN 385
G + C A G P+PTI W NG G L + V E+
Sbjct: 701 GIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEED 760
Query: 386 AGMYQCIAENTYGAIYANA---ELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAP 442
+G Y C N GA + + +KI A+ ++ LA +G + + C
Sbjct: 761 SGYYLCKVSNDVGADVSKSMYLTVKIPAMITSY-----PNTTLATQGQKKEMSCTAHGEK 815
Query: 443 KPKFSWSKG--------TEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKAN 494
W K +LV++ + +L+I R D G ++C A N+ G+
Sbjct: 816 PIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDR 875
Query: 495 STGTLVI---TDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDF-N 550
L + DP I + + A T++ FD +T GY I+ N
Sbjct: 876 GIIQLTVQEPPDPPEIEIKDVKA-----RTITLRWTMGFDGNSPIT------GYDIECKN 924
Query: 551 KENIHYQRNFMLDSNGEL---LIRNAQLKHAGRYTCTAQTIVDNSSASADLVV----RGP 603
K + D + +L I + A+ + S S +L + P
Sbjct: 925 KSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEAAP 984
Query: 604 PGPPGGLRIEDIRATSVALTWSRGSDN--HSPISKYTIQTKTILSDDWKDAKTDPPIIEG 661
GPP + +E I + S+ +TW + + I Y I + + G
Sbjct: 985 DGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSG 1044
Query: 662 NMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNR 721
+ E +L + +Y V A N G G PS T P+ P +V
Sbjct: 1045 DSEVYTLDNLNKFTQYGLVVQACNRAGTG-PSSQEIITTTLEDVPSYPPENVQAIATSPE 1103
Query: 722 ELTITWAPLSREYHYGNNFGYIVAF--KPFDGE--EWKKVTVTNPDTGRYVHKDETMSPS 777
++I+W+ LS+E G G+ V + DGE E K +T T P + + +
Sbjct: 1104 SISISWSTLSKEALNGILQGFRVIYWANLMDGELGEIKNITTTQPSL-----ELDGLEKY 1158
Query: 778 TAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHW--EHVLEK 835
T + ++V AF GDG S + +D P P V S+S + V W L
Sbjct: 1159 TNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPG-PPAGVKAAAASASMVFVSWLPPLKLNG 1217
Query: 836 IVESYQIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDM 895
I+ Y + + +H + + + +S R+ NL + QY + V A SAG G S++
Sbjct: 1218 IIRKYTV--FCSHPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEI 1275
Query: 896 IEAFTKKAPPSQPPRIIS 913
I T + P RI++
Sbjct: 1276 I---TVEPLAKAPARILT 1290
Score = 118 bits (295), Expect = 3e-26
Identities = 140/576 (24%), Positives = 224/576 (38%), Gaps = 60/576 (10%)
Query: 65 CRARASPFPVYKWRMNNGD--VDLTSDRYSMVGGNLVI-----NNPDKQKDAGIYYCLAS 117
C A P +W + G+ D+ R+ G L I ++ YYC A
Sbjct: 46 CPAAGIPPVTLRWYLATGEEIYDVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYCTAE 105
Query: 118 NNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGM-----VLLCDPPYHFPDDLSY-R 171
N G +RS + + +P+ VRV++ K M V C P ++
Sbjct: 106 NPSGKIRSQDVHIKAVLREPYT------VRVEDQKTMRGNVAVFKCIIPSSVEAYITVVS 159
Query: 172 WLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDK-GNYSCFVSSPSITKSVFSKFIPLI 230
W E + RF+ + G LYI +V+ D NY C ++ S L
Sbjct: 160 W---EKDTVSLVSGSRFLITSTGALYIKDVQNEDGLYNYRCITRHRYTGETRQSNSARLF 216
Query: 231 PIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEIST 290
+ P I+ F A+ GQ V L C ALG+P PD RW K P+ +
Sbjct: 217 VSDPANSAP---SILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQK 273
Query: 291 SGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYW 350
+ L I NI+ D G Y CE N G K R+YV+ + + +GS +
Sbjct: 274 TVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSL 333
Query: 351 PCVATGKPIPTIRWLKNGYAYHKGE-LRLYDVTFEN----------AGMYQCIAENTYGA 399
C TG + W +NG + G+ +R+ + EN G YQC
Sbjct: 334 SCSVTGTEDQELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRK--DK 391
Query: 400 IYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLV--N 457
+ A ++++ T ++ + + + V + C K P P +W+ + ++
Sbjct: 392 LSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGG 451
Query: 458 SSRI--LIWEDGS----LEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAP 511
S RI +I +G+ L I++ DGG+Y C A N+ G + + P I P
Sbjct: 452 SHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASI--RP 509
Query: 512 I-NADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLI 570
+ N G + + C P + W N ++ FN R ++NG L +
Sbjct: 510 MKNITAIAGRDTYIHCRVIGYPYYSIK--WYKNSNLLPFN------HRQVAFENNGTLKL 561
Query: 571 RNAQLK-HAGRYTCTAQTIVD-NSSASADLVVRGPP 604
+ Q + G YTC ++S S + V+ PP
Sbjct: 562 SDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPP 597
Score = 66.6 bits (161), Expect = 1e-10
Identities = 217/984 (22%), Positives = 360/984 (36%), Gaps = 157/984 (15%)
Query: 52 YPEESLEGKVSLNCRARASPFPV-YKWRMNN----GDVDLTSDRYSMVGGNLVINNPDKQ 106
+P S+ +V + C + P+ W+ + G + +T D +L I+N
Sbjct: 604 FPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTS-SLRISNLSLM 662
Query: 107 KDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEG---KGMVLLCDPPYH 163
+ G Y C+A N V + PP+ + R ++G K ++L C +
Sbjct: 663 HN-GNYTCIARNEAAAVEHQSQLIV-----RVPPKFVVQPRDQDGIYGKAVILNCSAEGY 716
Query: 164 FPDDLSYRWLLNE-FPVF--ITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSP---S 217
+ +++ P F I ++ R V +NG+L I +V D G Y C VS+
Sbjct: 717 PVPTIVWKFSKGAGVPQFQPIALNGRIQVL-SNGSLLIKHVVEEDSGYYLCKVSNDVGAD 775
Query: 218 ITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK 277
++KS++ T PA I A GQ + C A G +RW K
Sbjct: 776 VSKSMY------------LTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPIIVRWEK 823
Query: 278 ---VLEPMPSTAEISTSG------AVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQ 328
++ P + +ST + L+I ED G + C A N G+D+ ++ VQ
Sbjct: 824 EDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGEDRGIIQLTVQ 883
Query: 329 AFPEWVE-HINDTEV-------DIGSDLYWPCVATGKPIPTIRWLKNGYAYHKGELRLYD 380
P+ E I D + +G D P TG I KN R D
Sbjct: 884 EPPDPPEIEIKDVKARTITLRWTMGFDGNSPI--TGYDIEC----KNKSDSWDSAQRTKD 937
Query: 381 VT--FENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKP 438
V+ +A + +TY +I A+ +I P+ E+ + A G + +P
Sbjct: 938 VSPQLNSATIIDIHPSSTY-SIRMYAKNRIGKSEPSNELTITADEA-APDGPPQEVHLEP 995
Query: 439 KAAPKPKFSWSKGTEWLVNSS----RILIWE---DGSLEINNITRNDGGIYTCFAENNRG 491
++ + +W + L N +I E G+ + N I+ + G + +N
Sbjct: 996 ISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLN 1055
Query: 492 KANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPAL---------DLTFVWS- 541
K G LV+ R P + +I T++ S+ P ++ WS
Sbjct: 1056 KFTQYG-LVVQACNRAGTGPSSQEIIT---TTLEDVPSYPPENVQAIATSPESISISWST 1111
Query: 542 -----FNGYVIDFNKENIHYQRNFMLDSNGEL-----LIRNAQLKHAGRYT-----CTAQ 586
NG + F + Y N M GE+ + +L +YT A
Sbjct: 1112 LSKEALNGILQGFR---VIYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAF 1168
Query: 587 TIVDNSSASADLVVRGP---PGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKT 643
T + S + R PGPP G++ A+ V ++W + I KYT+
Sbjct: 1169 TRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSWLPPLKLNGIIRKYTVFCSH 1228
Query: 644 ILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDG 703
+ + P + R +L +Y VVA + GRG S I +
Sbjct: 1229 PYPTVISEFEASPDSF-----SYRIPNLSRNRQYSVWVVAVTSAGRGNSS---EIITVEP 1280
Query: 704 AAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFK----PFDGEEWKKVTV 759
A AP+ + G +T W ++ K P +W K +
Sbjct: 1281 LAK--APARILTFSGT---VTTPWMK-----------DIVLPCKAVGDPSPAVKWMKDSN 1324
Query: 760 TNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVA---------VINSAQDAPSE 810
P + S + VKA + G YS +A ++N P +
Sbjct: 1325 GTPSLVTIDGRRSIFSNGSFIIRTVKA---EDSGYYSCIANNNWGSDEIILNLQVQVPPD 1381
Query: 811 APTEVGVKVLSSSEISVHWEHVLE--KIVESYQIRYWAAHDKEEAANRVQVTSQEYSARL 868
P + V +SS I++ W + Y ++Y + D E ++ E S RL
Sbjct: 1382 QP-RLTVSKTTSSSITLSWLPGDNGGSSIRGYILQY--SEDNSEQWGSFPISPSERSYRL 1438
Query: 869 ENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPP--SQPPRIISSVRSG--SRYIIT 924
ENL T Y + A N G G S++IEA T P S+ + +S+ + +I
Sbjct: 1439 ENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQFSKEQELFASINTTRVRLNLIG 1498
Query: 925 WDHVVALSNESTVTGYKVLYRPDG 948
W+ +T + + YRP G
Sbjct: 1499 WN-----DGGCPITSFTLEYRPFG 1517
Score = 55.8 bits (133), Expect = 2e-07
Identities = 67/286 (23%), Positives = 108/286 (37%), Gaps = 30/286 (10%)
Query: 432 VIIECKPKAAPKPKFSWSK---GTEWLVN-SSRILIWEDGSLEINNITRNDGGIYTCFAE 487
+++ CK P P W K GT LV R I+ +GS I + D G Y+C A
Sbjct: 1303 IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIAN 1362
Query: 488 NNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVI 547
NN G L + P P +TV + + S+ P + S GY++
Sbjct: 1363 NNWGSDEIILNLQVQVP------PDQPRLTVSKTTSSSITLSWLPGDNGGS--SIRGYIL 1414
Query: 548 DFNKENIHYQRNFMLD-SNGELLIRNAQLKHAGRYTCTAQTIVDNSSAS----ADLVVRG 602
++++N +F + S + N + ++T TAQ V S A + +
Sbjct: 1415 QYSEDNSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKE 1474
Query: 603 PPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAK----TDPPI 658
P I T V L +D PI+ +T++ + + W A+ + I
Sbjct: 1475 PQFSKEQELFASINTTRVRLNLIGWNDGGCPITSFTLEYRPFGTTVWTTAQRTSLSKSYI 1534
Query: 659 IEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGA 704
+ EA W E + RV N+ G E + DG+
Sbjct: 1535 LYDLQEAT-------WYELQMRV--CNSAGCAEKQANFATLNYDGS 1571
Score = 52.8 bits (125), Expect = 2e-06
Identities = 73/322 (22%), Positives = 121/322 (37%), Gaps = 54/322 (16%)
Query: 314 NIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRW-LKNG---- 368
N+ +D H + +V A + V + T + PC A G P T+RW L G
Sbjct: 14 NVFSEDLHSSLYFVNASLQEVVFASTTGTLV------PCPAAGIPPVTLRWYLATGEEIY 67
Query: 369 ------YAYHKGELRLYDV------TFENAGMYQCIAENTYGAIYA-NAELKILALAP-T 414
+ + G L+++ T + Y C AEN G I + + +K + P T
Sbjct: 68 DVPGIRHVHPNGTLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIRSQDVHIKAVLREPYT 127
Query: 415 FEMNPMKKKILAAKGGRVIIECKPKAAPKPKF---SWSKGTEWLVNSSRILIWEDGSLEI 471
+ K +G + +C ++ + SW K T LV+ SR LI G+L I
Sbjct: 128 VRVEDQK----TMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGALYI 183
Query: 472 NNITRNDGGI-YTCFAEN---NRGKANSTGTLVITDPTR----IILAPINADITVGENAT 523
++ DG Y C + + +++ L ++DP I+ + G+
Sbjct: 184 KDVQNEDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVE 243
Query: 524 MQCAASFDPALDLTFVWSFNGYVIDFNKEN--IHYQRNFMLDSNGELLIRNAQLKHAGRY 581
+ C A P D ++ K+N + F G LLI N + +G Y
Sbjct: 244 LPCKALGHPEPDYRWL-----------KDNMPLELSGRFQKTVTG-LLIENIRPSDSGSY 291
Query: 582 TCTAQTIVDNSSASADLVVRGP 603
C + L V+ P
Sbjct: 292 VCEVSNRYGTAKVIGRLYVKQP 313
>gi|237858682 neurofascin isoform 6 precursor [Homo sapiens]
Length = 613
Score = 219 bits (559), Expect = 8e-57
Identities = 174/571 (30%), Positives = 250/571 (43%), Gaps = 47/571 (8%)
Query: 61 VSLNCRARASPFPVYKWRMNNGDVDLTSD-RYSMV--GGNLVIN-----NPDKQKDAGIY 112
+ + C A+ +P P + W N+ ++ D R SM G LVI+ P++ + G Y
Sbjct: 53 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYE--GEY 110
Query: 113 YCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRW 172
C A N +G S L +P E V V+EG + L C+PP P + + W
Sbjct: 111 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIF-W 169
Query: 173 LLNEFPVFITMDKRRFVSQT-NGNLYIANVEASD-KGNYSC-----FVSSPSITKSVFSK 225
+ + IT DKR VSQ NG+LY +NV D + +YSC F + K
Sbjct: 170 MSSSMEP-ITQDKR--VSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLK 226
Query: 226 FIPLIPIPERTTK-PYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPS 284
+ + ERT YP L G ++ LEC A G P PDI W K +PS
Sbjct: 227 VLTTRGVAERTPSFMYPQGTA---SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS 283
Query: 285 T-AEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVD 343
A+ L+I N+ ED G Y C A N G +H + V+A P W++ + +
Sbjct: 284 DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA 343
Query: 344 IGSDLYWPCVATGKPIPTIRWLKNGYAYHK----------GELRLY-DVTFENAGMYQCI 392
G D C A G P PT++W+ NG G+ ++ D + +YQC
Sbjct: 344 PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCN 403
Query: 393 AENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSK-G 451
N +G + ANA + +L + P ++P + I R ++C +P P W K G
Sbjct: 404 TSNEHGYLLANAFVSVLDVPPRM-LSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNG 462
Query: 452 TEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAP 511
++ ++E+GSLEI I + D GIYTC A N GKA + L + DPTRI P
Sbjct: 463 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMP 522
Query: 512 INADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIR 571
+ G ++C DP+L LT W + Y N M + L I
Sbjct: 523 EDQVARRGTTVQLECRVKHDPSLKLTVSW--------LKDDEPLYIGNRMKKEDDSLTIF 574
Query: 572 NAQLKHAGRYTCTAQTIVDNSSASADLVVRG 602
+ G YTC A T +D A A L V G
Sbjct: 575 GVAERDQGSYTCVASTELDQDLAKAYLTVLG 605
Score = 83.6 bits (205), Expect = 9e-16
Identities = 88/365 (24%), Positives = 149/365 (40%), Gaps = 30/365 (8%)
Query: 63 LNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLASNNYGM 122
L C A P P W GD+ ++ L I N ++ D+G Y+CLASN G
Sbjct: 260 LECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEE-DSGEYFCLASNKMGS 318
Query: 123 VRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPV-FI 181
+R T + P+ +E + + G+ L+C + + +W++N P+
Sbjct: 319 IRHTISVRVKAA--PYWLDEPKNLILAPGEDGRLVCRANGN--PKPTVQWMVNGEPLQSA 374
Query: 182 TMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPYP 241
+ R V+ + + + S + Y C S+ + + F+ ++ +P R P
Sbjct: 375 PPNPNREVA--GDTIIFRDTQISSRAVYQCNTSNEH-GYLLANAFVSVLDVPPRMLSPRN 431
Query: 242 ADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMP---STAEISTSGAVLKIF 298
I V ++ L+C G+P+P +RW K + + +G+ L+I
Sbjct: 432 QLIRV-------ILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS-LEIK 483
Query: 299 NIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKP 358
I+ ED+GIY C A NI GK ++Q R+ V+ D G+ + C P
Sbjct: 484 MIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDP 543
Query: 359 IP--TIRWLKNGYAYHKGE--------LRLYDVTFENAGMYQCIAENTYGAIYANAELKI 408
T+ WLK+ + G L ++ V + G Y C+A A A L +
Sbjct: 544 SLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 603
Query: 409 LALAP 413
L P
Sbjct: 604 LGNCP 608
Score = 79.0 bits (193), Expect = 2e-14
Identities = 113/474 (23%), Positives = 180/474 (37%), Gaps = 63/474 (13%)
Query: 169 SYRWLLNEFPVFITMDKRRFVSQTNGNLYI----ANVEASDKGNYSCFVSSPSITKSVFS 224
S+ W N I D R + + +G L I +G Y CF + T S
Sbjct: 66 SFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGT--ALS 123
Query: 225 KFIPL----IPI-PERTTKPYPADIVVQFKDVYALMGQNVTLECFAL-GNPVPDIRWRKV 278
I L P+ P+ P +VVQ G +TL+C G P P I W
Sbjct: 124 NRIRLQVSKSPLWPKENLDP----VVVQ-------EGAPLTLQCNPPPGLPSPVIFWMSS 172
Query: 279 -LEPMPSTAEISTS-GAVLKIFNIQLED-EGIYECEAE-----NIRGKDKHQARIYV--- 327
+EP+ +S L N+ L+D + Y C A I+ K+ ++
Sbjct: 173 SMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRG 232
Query: 328 --QAFPEWVEHINDTEVDI---GSDLYWPCVATGKPIPTIRWLKNG---------YAYHK 373
+ P ++ + G DL C+A+G P P I W K G +
Sbjct: 233 VAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFN 292
Query: 374 GELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVI 433
LR+ +V+ E++G Y C+A N G+I +++ A AP + P + + GR++
Sbjct: 293 KALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA-APYWLDEPKNLILAPGEDGRLV 351
Query: 434 IECKPKAAPKPKFSWSKGTEWLV----NSSRILIWEDGSLEINNITRNDGGIYTCFAENN 489
C+ PKP W E L N +R + + ++ + + +Y C N
Sbjct: 352 --CRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TIIFRDTQISSRAVYQCNTSNE 407
Query: 490 RGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDF 549
G + + + D +L+P N I V + F + T W NG +
Sbjct: 408 HGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNL 467
Query: 550 NKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGP 603
+ N H N G L I+ + + G YTC A I+ + L V+ P
Sbjct: 468 DGGNYHVYEN------GSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDP 515
Score = 76.6 bits (187), Expect = 1e-13
Identities = 91/386 (23%), Positives = 142/386 (36%), Gaps = 40/386 (10%)
Query: 230 IPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK-----VLEPMPS 284
I IP T+P P KD N+ +EC A GNP P W + + P
Sbjct: 25 IEIPMDLTQP-PTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPR 83
Query: 285 TAEISTSGAVLKIFNI---QLEDEGIYECEAENIRGKD-KHQARIYVQAFPEW-VEHIND 339
+ SG ++ F E EG Y+C A N G ++ R+ V P W E+++
Sbjct: 84 VSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP 143
Query: 340 TEVDIGSDLYWPC-VATGKPIPTIRWL----------KNGYAYHKGELRLYDVTFENAGM 388
V G+ L C G P P I W+ K H G+L +V ++
Sbjct: 144 VVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQT 203
Query: 389 -YQCIAENTYGAIYANAE---LKILALAPTFEMNP-------MKKKILAAKGGRVIIECK 437
Y C A + LK+L E P + +G +++EC
Sbjct: 204 DYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECI 263
Query: 438 PKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTG 497
P P +W K L + + +L I N++ D G Y C A N G T
Sbjct: 264 ASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTI 323
Query: 498 TLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQ 557
++ + + P N + GE+ + C A+ +P T W NG + N + +
Sbjct: 324 SVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNP--KPTVQWMVNGEPLQSAPPNPNRE 381
Query: 558 RNFMLDSNGELLIRNAQLKHAGRYTC 583
+ ++ R+ Q+ Y C
Sbjct: 382 -----VAGDTIIFRDTQISSRAVYQC 402
Score = 50.8 bits (120), Expect = 6e-06
Identities = 40/160 (25%), Positives = 69/160 (43%), Gaps = 8/160 (5%)
Query: 57 LEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLA 116
L + L+C SP P +W N +L Y + + +++D GIY C+A
Sbjct: 438 LYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVA 497
Query: 117 SNNYGMVRSTEATLSFGYLDPFPPEERPEVRV-KEGKGMVLLCDPPYHFPDDLSYRWLLN 175
+N G E + DP PE +V + G + L C + L+ WL +
Sbjct: 498 TNILG---KAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 554
Query: 176 EFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSS 215
+ P++I + + + +L I V D+G+Y+C S+
Sbjct: 555 DEPLYI----GNRMKKEDDSLTIFGVAERDQGSYTCVAST 590
>gi|237858680 neurofascin isoform 5 precursor [Homo sapiens]
Length = 619
Score = 219 bits (559), Expect = 8e-57
Identities = 174/571 (30%), Positives = 250/571 (43%), Gaps = 47/571 (8%)
Query: 61 VSLNCRARASPFPVYKWRMNNGDVDLTSD-RYSMV--GGNLVIN-----NPDKQKDAGIY 112
+ + C A+ +P P + W N+ ++ D R SM G LVI+ P++ + G Y
Sbjct: 59 ILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYE--GEY 116
Query: 113 YCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRW 172
C A N +G S L +P E V V+EG + L C+PP P + + W
Sbjct: 117 QCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIF-W 175
Query: 173 LLNEFPVFITMDKRRFVSQT-NGNLYIANVEASD-KGNYSC-----FVSSPSITKSVFSK 225
+ + IT DKR VSQ NG+LY +NV D + +YSC F + K
Sbjct: 176 MSSSMEP-ITQDKR--VSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLK 232
Query: 226 FIPLIPIPERTTK-PYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPS 284
+ + ERT YP L G ++ LEC A G P PDI W K +PS
Sbjct: 233 VLTTRGVAERTPSFMYPQGTA---SSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPS 289
Query: 285 T-AEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVD 343
A+ L+I N+ ED G Y C A N G +H + V+A P W++ + +
Sbjct: 290 DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILA 349
Query: 344 IGSDLYWPCVATGKPIPTIRWLKNGYAYHK----------GELRLY-DVTFENAGMYQCI 392
G D C A G P PT++W+ NG G+ ++ D + +YQC
Sbjct: 350 PGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCN 409
Query: 393 AENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSK-G 451
N +G + ANA + +L + P ++P + I R ++C +P P W K G
Sbjct: 410 TSNEHGYLLANAFVSVLDVPPRM-LSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNG 468
Query: 452 TEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAP 511
++ ++E+GSLEI I + D GIYTC A N GKA + L + DPTRI P
Sbjct: 469 QGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMP 528
Query: 512 INADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIR 571
+ G ++C DP+L LT W + Y N M + L I
Sbjct: 529 EDQVARRGTTVQLECRVKHDPSLKLTVSW--------LKDDEPLYIGNRMKKEDDSLTIF 580
Query: 572 NAQLKHAGRYTCTAQTIVDNSSASADLVVRG 602
+ G YTC A T +D A A L V G
Sbjct: 581 GVAERDQGSYTCVASTELDQDLAKAYLTVLG 611
Score = 83.6 bits (205), Expect = 9e-16
Identities = 88/365 (24%), Positives = 149/365 (40%), Gaps = 30/365 (8%)
Query: 63 LNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLASNNYGM 122
L C A P P W GD+ ++ L I N ++ D+G Y+CLASN G
Sbjct: 266 LECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEE-DSGEYFCLASNKMGS 324
Query: 123 VRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPV-FI 181
+R T + P+ +E + + G+ L+C + + +W++N P+
Sbjct: 325 IRHTISVRVKAA--PYWLDEPKNLILAPGEDGRLVCRANGN--PKPTVQWMVNGEPLQSA 380
Query: 182 TMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPERTTKPYP 241
+ R V+ + + + S + Y C S+ + + F+ ++ +P R P
Sbjct: 381 PPNPNREVA--GDTIIFRDTQISSRAVYQCNTSNEH-GYLLANAFVSVLDVPPRMLSPRN 437
Query: 242 ADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMP---STAEISTSGAVLKIF 298
I V ++ L+C G+P+P +RW K + + +G+ L+I
Sbjct: 438 QLIRV-------ILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGS-LEIK 489
Query: 299 NIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKP 358
I+ ED+GIY C A NI GK ++Q R+ V+ D G+ + C P
Sbjct: 490 MIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDP 549
Query: 359 IP--TIRWLKNGYAYHKGE--------LRLYDVTFENAGMYQCIAENTYGAIYANAELKI 408
T+ WLK+ + G L ++ V + G Y C+A A A L +
Sbjct: 550 SLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 609
Query: 409 LALAP 413
L P
Sbjct: 610 LGNCP 614
Score = 79.0 bits (193), Expect = 2e-14
Identities = 113/474 (23%), Positives = 180/474 (37%), Gaps = 63/474 (13%)
Query: 169 SYRWLLNEFPVFITMDKRRFVSQTNGNLYI----ANVEASDKGNYSCFVSSPSITKSVFS 224
S+ W N I D R + + +G L I +G Y CF + T S
Sbjct: 72 SFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGT--ALS 129
Query: 225 KFIPL----IPI-PERTTKPYPADIVVQFKDVYALMGQNVTLECFAL-GNPVPDIRWRKV 278
I L P+ P+ P +VVQ G +TL+C G P P I W
Sbjct: 130 NRIRLQVSKSPLWPKENLDP----VVVQ-------EGAPLTLQCNPPPGLPSPVIFWMSS 178
Query: 279 -LEPMPSTAEISTS-GAVLKIFNIQLED-EGIYECEAE-----NIRGKDKHQARIYV--- 327
+EP+ +S L N+ L+D + Y C A I+ K+ ++
Sbjct: 179 SMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRG 238
Query: 328 --QAFPEWVEHINDTEVDI---GSDLYWPCVATGKPIPTIRWLKNG---------YAYHK 373
+ P ++ + G DL C+A+G P P I W K G +
Sbjct: 239 VAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFN 298
Query: 374 GELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVI 433
LR+ +V+ E++G Y C+A N G+I +++ A AP + P + + GR++
Sbjct: 299 KALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKA-APYWLDEPKNLILAPGEDGRLV 357
Query: 434 IECKPKAAPKPKFSWSKGTEWLV----NSSRILIWEDGSLEINNITRNDGGIYTCFAENN 489
C+ PKP W E L N +R + + ++ + + +Y C N
Sbjct: 358 --CRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD--TIIFRDTQISSRAVYQCNTSNE 413
Query: 490 RGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDF 549
G + + + D +L+P N I V + F + T W NG +
Sbjct: 414 HGYLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNL 473
Query: 550 NKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGP 603
+ N H N G L I+ + + G YTC A I+ + L V+ P
Sbjct: 474 DGGNYHVYEN------GSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDP 521
Score = 76.3 bits (186), Expect = 1e-13
Identities = 89/383 (23%), Positives = 141/383 (36%), Gaps = 46/383 (12%)
Query: 233 PERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK-----VLEPMPSTAE 287
P TK D +V +D N+ +EC A GNP P W + + P +
Sbjct: 40 PPTITKQSAKDHIVDPRD-------NILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSM 92
Query: 288 ISTSGAVLKIFNI---QLEDEGIYECEAENIRGKD-KHQARIYVQAFPEW-VEHINDTEV 342
SG ++ F E EG Y+C A N G ++ R+ V P W E+++ V
Sbjct: 93 RRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVV 152
Query: 343 DIGSDLYWPC-VATGKPIPTIRWL----------KNGYAYHKGELRLYDVTFENAGM-YQ 390
G+ L C G P P I W+ K H G+L +V ++ Y
Sbjct: 153 QEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYS 212
Query: 391 CIAENTYGAIYANAE---LKILALAPTFEMNP-------MKKKILAAKGGRVIIECKPKA 440
C A + LK+L E P + +G +++EC
Sbjct: 213 CNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASG 272
Query: 441 APKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLV 500
P P +W K L + + +L I N++ D G Y C A N G T ++
Sbjct: 273 VPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVR 332
Query: 501 ITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNF 560
+ + P N + GE+ + C A+ +P T W NG + N + +
Sbjct: 333 VKAAPYWLDEPKNLILAPGEDGRLVCRANGNP--KPTVQWMVNGEPLQSAPPNPNRE--- 387
Query: 561 MLDSNGELLIRNAQLKHAGRYTC 583
+ ++ R+ Q+ Y C
Sbjct: 388 --VAGDTIIFRDTQISSRAVYQC 408
Score = 50.8 bits (120), Expect = 6e-06
Identities = 40/160 (25%), Positives = 69/160 (43%), Gaps = 8/160 (5%)
Query: 57 LEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLA 116
L + L+C SP P +W N +L Y + + +++D GIY C+A
Sbjct: 444 LYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVA 503
Query: 117 SNNYGMVRSTEATLSFGYLDPFPPEERPEVRV-KEGKGMVLLCDPPYHFPDDLSYRWLLN 175
+N G E + DP PE +V + G + L C + L+ WL +
Sbjct: 504 TNILG---KAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 560
Query: 176 EFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSS 215
+ P++I + + + +L I V D+G+Y+C S+
Sbjct: 561 DEPLYI----GNRMKKEDDSLTIFGVAERDQGSYTCVAST 596
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform
1 precursor [Homo sapiens]
Length = 1907
Score = 201 bits (512), Expect = 2e-51
Identities = 185/672 (27%), Positives = 294/672 (43%), Gaps = 70/672 (10%)
Query: 352 CVATGKPIPTIRWLKNGYAYHKGELRLYDVTFENAG---------------MYQCIAENT 396
C ATG+P P I W+K G + + + AG +Y+C A N+
Sbjct: 54 CQATGEPKPRITWMKKGKKVSSQRFEVIEFD-DGAGSVLRIQPLRVQRDEAIYECTATNS 112
Query: 397 YGAIYANAELKILALA------PTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSK 450
G I +A+L +L P+ +M P K + A+ ++ C P P+ SW K
Sbjct: 113 LGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATML--CAAGGNPDPEISWFK 170
Query: 451 G---TEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRI 507
+ ++ RI G+L+I + +D G Y C A N+ G S + R+
Sbjct: 171 DFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRV 230
Query: 508 I----LAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLD 563
+ P + ++ G + + C A P + +V G ++ + RN +
Sbjct: 231 APRFSIPPSSQEVMPGGSVNLTCVAVGAP---MPYVKWMMGAEELTKEDEMPVGRNVLEL 287
Query: 564 SNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALT 623
SN ++R+A YTC A + + A+A + V+ P PP L + + ATSV LT
Sbjct: 288 SN---VVRSAN------YTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLT 338
Query: 624 WSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVD---LIPWMEYEFR 680
W G N P++ Y IQ ++ A T+ P E + A L P+ EY FR
Sbjct: 339 WDSG--NSEPVTYYGIQ--------YRAAGTEGPFQEVDGVATTRYSIGGLSPFSEYAFR 388
Query: 681 VVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNF 740
V+A N++GRG PS + R +T AP+ P V + + W P E G
Sbjct: 389 VLAVNSIGRGPPS-EAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEP--PEEPNGLVR 445
Query: 741 GYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAV 800
GY V + P N D G + ++ P + ++V AF GDGP S
Sbjct: 446 GYRVYYTPDSRRPPNAWHKHNTDAG-LLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQ 504
Query: 801 INSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIVESYQIRYWAAHDKEEAANRVQVT 860
+ + Q P++ P + +V S + I + W ++ + Y++ YWAA D+++
Sbjct: 505 VKTQQGVPAQ-PADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDP 563
Query: 861 SQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSR 920
+ Y+ LE+L PDT Y ++ A + G G + IEA T ++ PS PP+ + V GS
Sbjct: 564 TSSYT--LEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGST 621
Query: 921 YI-ITWDHVVALSNESTVTGYKVLYRP-DGQHDGK-----LYSTHKHSIEVPIPRDGEYV 973
+ ++W A S +T Y V Y DG+ G+ + H V + + EY
Sbjct: 622 TVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYR 681
Query: 974 VEVRAHSDGGDG 985
V VRAH+D G G
Sbjct: 682 VWVRAHTDVGPG 693
Score = 112 bits (280), Expect = 2e-24
Identities = 145/592 (24%), Positives = 236/592 (39%), Gaps = 80/592 (13%)
Query: 429 GGRVIIECKPKAAPKPKFSW-SKGTEWLVNSSRILIWEDGSLEINNI----TRNDGGIYT 483
GG C+ PKP+ +W KG + ++ ++DG+ + I + D IY
Sbjct: 47 GGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYE 106
Query: 484 CFAENNRGKANSTGTLVITDPTR-------IILAPINADITVGENATMQCAASFDPALDL 536
C A N+ G+ N++ L + + + I + P + ATM CAA +P D
Sbjct: 107 CTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNP--DP 164
Query: 537 TFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNS-SAS 595
W + +D N ++ +G L I +++ G+Y C A SA
Sbjct: 165 EISWFKDFLPVDPATSNGRIKQL----RSGALQIESSEESDQGKYECVATNSAGTRYSAP 220
Query: 596 ADLVVRG---------PPGP----PGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTK 642
A+L VR PP PGG + T VA+ P K+ + +
Sbjct: 221 ANLYVRVRRVAPRFSIPPSSQEVMPGG----SVNLTCVAV------GAPMPYVKWMMGAE 270
Query: 643 TILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTD 702
+ +D + P+ +E + V + VA ++LG I + T
Sbjct: 271 ELTKED------EMPVGRNVLELSNVV-----RSANYTCVAISSLG----MIEATAQVTV 315
Query: 703 GAAPNVAPSDVGGGGGRNRELTITWAPLSRE--YHYGNNFGYIVAFKPFDGEEWKKVTVT 760
A P P D+ +T+TW + E +YG + PF +E V T
Sbjct: 316 KALPK-PPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPF--QEVDGVATT 372
Query: 761 NPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVL 820
G +SP + + +V A N+ G GP S + + APS P V ++L
Sbjct: 373 RYSIG-------GLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARML 425
Query: 821 SSSEISVHWEHVLEK--IVESYQIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYF 878
S+S + V WE E +V Y++ Y + A T + +LLP Y
Sbjct: 426 SASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYS 485
Query: 879 IEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVT 938
+ V A + G GPPS I+ T++ P+QP + V S +R ++W L + +
Sbjct: 486 LRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSW----LLPPQERII 541
Query: 939 GYKVLY----RPDGQHDGKLYSTHKHSIEVPIPRDGEYVVEVRAHSDGGDGV 986
Y+++Y D QH T +++E + D Y ++ A SD G GV
Sbjct: 542 MYELVYWAAEDEDQQHKVTFDPTSSYTLE-DLKPDTLYRFQLAARSDMGVGV 592
Score = 82.4 bits (202), Expect = 2e-15
Identities = 100/438 (22%), Positives = 170/438 (38%), Gaps = 48/438 (10%)
Query: 601 RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIE 660
+G P P + E T + L+W I Y + +D + T P
Sbjct: 509 QGVPAQPADFQAEVESDTRIQLSWLLPPQER--IIMYELVYWAAEDEDQQHKVTFDPTSS 566
Query: 661 GNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRN 720
+E DL P Y F++ A + +G G + P+ +T + P+ P V +
Sbjct: 567 YTLE-----DLKPDTLYRFQLAARSDMGVGVFT-PTIEARTAQSTPSAPPQKVMCVSMGS 620
Query: 721 RELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAF 780
+ ++W P + G Y VA++ DGE+ + V + T +
Sbjct: 621 TTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEY 680
Query: 781 QVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEK----I 836
+V V+A + G GP S ++ + +D PS P +V V+ L+S+ + V+W+ +
Sbjct: 681 RVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQ 740
Query: 837 VESYQIRYWAAHDKE-------------EAANRVQVTSQEYSARLENLLPDTQYFIEVGA 883
+ YQ+ Y + E EA R + S++Y + L P+T Y + V A
Sbjct: 741 IRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPE-ESEDYETTISGLTPETTYSVTVAA 799
Query: 884 CNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVL 943
+ G G S T A P +P +IS+ + ++ W L E + GY++
Sbjct: 800 YTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTA-LLQWHPPKELPGE--LLGYRLQ 856
Query: 944 Y------RPD----GQHDGKLYSTHKHSIEVPIPR---------DGEYVVEVRAHSDGGD 984
Y RP+ G+ D T H I R E+ E+R D
Sbjct: 857 YCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPS 916
Query: 985 GVVSQVKISGAPTLSPSL 1002
G + ++G T + L
Sbjct: 917 GFPQNLHVTGLTTSTTEL 934
Score = 74.7 bits (182), Expect = 4e-13
Identities = 75/306 (24%), Positives = 132/306 (43%), Gaps = 32/306 (10%)
Query: 44 EEQPINTIYPEESLE---GKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMV------ 94
+ +P+ PE+ G S C+A P P W V +S R+ ++
Sbjct: 30 DSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKV--SSQRFEVIEFDDGA 87
Query: 95 GGNLVINNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPP-----EERPEVRVK 149
G L I Q+D IY C A+N+ G + +T A LS + PP + P+++V
Sbjct: 88 GSVLRIQPLRVQRDEAIYECTATNSLGEI-NTSAKLSVLEEEQLPPGFPSIDMGPQLKVV 146
Query: 150 E-GKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGN 208
E + +LC + ++S W + PV R +G L I + E SD+G
Sbjct: 147 EKARTATMLCAAGGNPDPEIS--WFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGK 204
Query: 209 YSCFVSSPSITK--SVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFAL 266
Y C ++ + T+ + + ++ + + R + P + V+ G +V L C A+
Sbjct: 205 YECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMP--------GGSVNLTCVAV 256
Query: 267 GNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIY 326
G P+P ++W E + E+ VL++ N+ Y C A + G + A++
Sbjct: 257 GAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSAN--YTCVAISSLGMIEATAQVT 314
Query: 327 VQAFPE 332
V+A P+
Sbjct: 315 VKALPK 320
Score = 62.8 bits (151), Expect = 2e-09
Identities = 53/172 (30%), Positives = 81/172 (47%), Gaps = 20/172 (11%)
Query: 257 QNVTLECFALGNPVPDIRWRK---VLEPMPSTAEIST--SGAVLKIFNIQLEDEGIYECE 311
+ T+ C A GNP P+I W K ++P S I SGA L+I + + D+G YEC
Sbjct: 150 RTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGA-LQIESSEESDQGKYECV 208
Query: 312 AENIRG-KDKHQARIYVQA---FPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKN 367
A N G + A +YV+ P + + EV G + CVA G P+P ++W+
Sbjct: 209 ATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMG 268
Query: 368 GYAYHKGE--------LRLYDVTFENAGMYQCIAENTYGAIYANAELKILAL 411
K + L L +V + Y C+A ++ G I A A++ + AL
Sbjct: 269 AEELTKEDEMPVGRNVLELSNVV--RSANYTCVAISSLGMIEATAQVTVKAL 318
Score = 58.9 bits (141), Expect = 2e-08
Identities = 104/443 (23%), Positives = 165/443 (37%), Gaps = 54/443 (12%)
Query: 585 AQTIVDNSSASADLVVRG----PPGPPGGLRIEDIRATSVALTWSRG--SDNHSPISKYT 638
A T V S+ ++VR P GPP + +E + +T+V + W S H I Y
Sbjct: 686 AHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQ 745
Query: 639 IQTKTILSDDWKDAKT--DPPIIEGNMEAARAVD-------LIPWMEYEFRVVATNTLGR 689
+ + + + + D + E + D L P Y V A T G
Sbjct: 746 VTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGD 805
Query: 690 GEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPF 749
G S P + T GA P P+ + N L + W P +E G GY + +
Sbjct: 806 GARSKPKI-VTTTGAVPG-RPTMMISTTAMNTAL-LQWHP-PKELP-GELLGYRLQYCRA 860
Query: 750 D---------GEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAV 800
D G++ + TVT +HK T + ++ A N G G
Sbjct: 861 DEARPNTIDFGKDDQHFTVTG------LHK------GTTYIFRLAAKNRAGLGE-EFEKE 907
Query: 801 INSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIVESYQIRYWAAHDKEEAANRVQVT 860
I + +D PS P + V L++S + W+ + I Y + +Q
Sbjct: 908 IRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNI 967
Query: 861 SQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSR 920
+ + L L PDT Y I+V A S G GP S I++ T + +
Sbjct: 968 TTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTS 1027
Query: 921 YIITWDHVVALSNESTVTGYKVLYRPDGQHDGKLYSTHKHSIE---VPIPRDGEYVVEVR 977
+++W+ V S +S V +K+LY +G+ HS+ + + EY +
Sbjct: 1028 VLLSWE--VPDSYKSAVP-FKILY------NGQSVEVDGHSMRKLIADLQPNTEYSFVLM 1078
Query: 978 AHSDGGDGVVSQVKISGAPTLSP 1000
G+ V I AP L P
Sbjct: 1079 NRGSSAGGLQHLVSIRTAPDLLP 1101
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform
2 precursor [Homo sapiens]
Length = 1898
Score = 201 bits (512), Expect = 2e-51
Identities = 185/672 (27%), Positives = 294/672 (43%), Gaps = 70/672 (10%)
Query: 352 CVATGKPIPTIRWLKNGYAYHKGELRLYDVTFENAG---------------MYQCIAENT 396
C ATG+P P I W+K G + + + AG +Y+C A N+
Sbjct: 54 CQATGEPKPRITWMKKGKKVSSQRFEVIEFD-DGAGSVLRIQPLRVQRDEAIYECTATNS 112
Query: 397 YGAIYANAELKILALA------PTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSK 450
G I +A+L +L P+ +M P K + A+ ++ C P P+ SW K
Sbjct: 113 LGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATML--CAAGGNPDPEISWFK 170
Query: 451 G---TEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRI 507
+ ++ RI G+L+I + +D G Y C A N+ G S + R+
Sbjct: 171 DFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRV 230
Query: 508 I----LAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLD 563
+ P + ++ G + + C A P + +V G ++ + RN +
Sbjct: 231 APRFSIPPSSQEVMPGGSVNLTCVAVGAP---MPYVKWMMGAEELTKEDEMPVGRNVLEL 287
Query: 564 SNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALT 623
SN ++R+A YTC A + + A+A + V+ P PP L + + ATSV LT
Sbjct: 288 SN---VVRSAN------YTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLT 338
Query: 624 WSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVD---LIPWMEYEFR 680
W G N P++ Y IQ ++ A T+ P E + A L P+ EY FR
Sbjct: 339 WDSG--NSEPVTYYGIQ--------YRAAGTEGPFQEVDGVATTRYSIGGLSPFSEYAFR 388
Query: 681 VVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNF 740
V+A N++GRG PS + R +T AP+ P V + + W P E G
Sbjct: 389 VLAVNSIGRGPPS-EAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEP--PEEPNGLVR 445
Query: 741 GYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAV 800
GY V + P N D G + ++ P + ++V AF GDGP S
Sbjct: 446 GYRVYYTPDSRRPPNAWHKHNTDAG-LLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQ 504
Query: 801 INSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIVESYQIRYWAAHDKEEAANRVQVT 860
+ + Q P++ P + +V S + I + W ++ + Y++ YWAA D+++
Sbjct: 505 VKTQQGVPAQ-PADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDP 563
Query: 861 SQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSR 920
+ Y+ LE+L PDT Y ++ A + G G + IEA T ++ PS PP+ + V GS
Sbjct: 564 TSSYT--LEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGST 621
Query: 921 YI-ITWDHVVALSNESTVTGYKVLYRP-DGQHDGK-----LYSTHKHSIEVPIPRDGEYV 973
+ ++W A S +T Y V Y DG+ G+ + H V + + EY
Sbjct: 622 TVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYR 681
Query: 974 VEVRAHSDGGDG 985
V VRAH+D G G
Sbjct: 682 VWVRAHTDVGPG 693
Score = 112 bits (280), Expect = 2e-24
Identities = 145/592 (24%), Positives = 236/592 (39%), Gaps = 80/592 (13%)
Query: 429 GGRVIIECKPKAAPKPKFSW-SKGTEWLVNSSRILIWEDGSLEINNI----TRNDGGIYT 483
GG C+ PKP+ +W KG + ++ ++DG+ + I + D IY
Sbjct: 47 GGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYE 106
Query: 484 CFAENNRGKANSTGTLVITDPTR-------IILAPINADITVGENATMQCAASFDPALDL 536
C A N+ G+ N++ L + + + I + P + ATM CAA +P D
Sbjct: 107 CTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNP--DP 164
Query: 537 TFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNS-SAS 595
W + +D N ++ +G L I +++ G+Y C A SA
Sbjct: 165 EISWFKDFLPVDPATSNGRIKQL----RSGALQIESSEESDQGKYECVATNSAGTRYSAP 220
Query: 596 ADLVVRG---------PPGP----PGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTK 642
A+L VR PP PGG + T VA+ P K+ + +
Sbjct: 221 ANLYVRVRRVAPRFSIPPSSQEVMPGG----SVNLTCVAV------GAPMPYVKWMMGAE 270
Query: 643 TILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTD 702
+ +D + P+ +E + V + VA ++LG I + T
Sbjct: 271 ELTKED------EMPVGRNVLELSNVV-----RSANYTCVAISSLG----MIEATAQVTV 315
Query: 703 GAAPNVAPSDVGGGGGRNRELTITWAPLSRE--YHYGNNFGYIVAFKPFDGEEWKKVTVT 760
A P P D+ +T+TW + E +YG + PF +E V T
Sbjct: 316 KALPK-PPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPF--QEVDGVATT 372
Query: 761 NPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVL 820
G +SP + + +V A N+ G GP S + + APS P V ++L
Sbjct: 373 RYSIG-------GLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARML 425
Query: 821 SSSEISVHWEHVLEK--IVESYQIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYF 878
S+S + V WE E +V Y++ Y + A T + +LLP Y
Sbjct: 426 SASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYS 485
Query: 879 IEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVT 938
+ V A + G GPPS I+ T++ P+QP + V S +R ++W L + +
Sbjct: 486 LRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSW----LLPPQERII 541
Query: 939 GYKVLY----RPDGQHDGKLYSTHKHSIEVPIPRDGEYVVEVRAHSDGGDGV 986
Y+++Y D QH T +++E + D Y ++ A SD G GV
Sbjct: 542 MYELVYWAAEDEDQQHKVTFDPTSSYTLE-DLKPDTLYRFQLAARSDMGVGV 592
Score = 80.1 bits (196), Expect = 1e-14
Identities = 95/428 (22%), Positives = 166/428 (38%), Gaps = 37/428 (8%)
Query: 601 RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIE 660
+G P P + E T + L+W I Y + +D + T P
Sbjct: 509 QGVPAQPADFQAEVESDTRIQLSWLLPPQER--IIMYELVYWAAEDEDQQHKVTFDPTSS 566
Query: 661 GNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRN 720
+E DL P Y F++ A + +G G + P+ +T + P+ P V +
Sbjct: 567 YTLE-----DLKPDTLYRFQLAARSDMGVGVFT-PTIEARTAQSTPSAPPQKVMCVSMGS 620
Query: 721 RELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAF 780
+ ++W P + G Y VA++ DGE+ + V + T +
Sbjct: 621 TTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEY 680
Query: 781 QVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEK----I 836
+V V+A + G GP S ++ + +D PS P +V V+ L+S+ + V+W+ +
Sbjct: 681 RVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQ 740
Query: 837 VESYQIRYWAAHDKEEAANRV---QVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPS 893
+ YQ+ Y + E + + ++ + L P+T Y + V A + G G S
Sbjct: 741 IRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARS 800
Query: 894 DMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLY------RPD 947
T A P +P +IS+ + ++ W L E + GY++ Y RP+
Sbjct: 801 KPKIVTTTGAVPGRPTMMISTTAMNTA-LLQWHPPKELPGE--LLGYRLQYCRADEARPN 857
Query: 948 ----GQHDGKLYSTHKHSIEVPIPR---------DGEYVVEVRAHSDGGDGVVSQVKISG 994
G+ D T H I R E+ E+R D G + ++G
Sbjct: 858 TIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTG 917
Query: 995 APTLSPSL 1002
T + L
Sbjct: 918 LTTSTTEL 925
Score = 74.7 bits (182), Expect = 4e-13
Identities = 75/306 (24%), Positives = 132/306 (43%), Gaps = 32/306 (10%)
Query: 44 EEQPINTIYPEESLE---GKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMV------ 94
+ +P+ PE+ G S C+A P P W V +S R+ ++
Sbjct: 30 DSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKV--SSQRFEVIEFDDGA 87
Query: 95 GGNLVINNPDKQKDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPP-----EERPEVRVK 149
G L I Q+D IY C A+N+ G + +T A LS + PP + P+++V
Sbjct: 88 GSVLRIQPLRVQRDEAIYECTATNSLGEI-NTSAKLSVLEEEQLPPGFPSIDMGPQLKVV 146
Query: 150 E-GKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGN 208
E + +LC + ++S W + PV R +G L I + E SD+G
Sbjct: 147 EKARTATMLCAAGGNPDPEIS--WFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGK 204
Query: 209 YSCFVSSPSITK--SVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFAL 266
Y C ++ + T+ + + ++ + + R + P + V+ G +V L C A+
Sbjct: 205 YECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMP--------GGSVNLTCVAV 256
Query: 267 GNPVPDIRWRKVLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIY 326
G P+P ++W E + E+ VL++ N+ Y C A + G + A++
Sbjct: 257 GAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSAN--YTCVAISSLGMIEATAQVT 314
Query: 327 VQAFPE 332
V+A P+
Sbjct: 315 VKALPK 320
Score = 63.5 bits (153), Expect = 9e-10
Identities = 101/434 (23%), Positives = 163/434 (37%), Gaps = 45/434 (10%)
Query: 585 AQTIVDNSSASADLVVRG----PPGPPGGLRIEDIRATSVALTWSRG--SDNHSPISKYT 638
A T V S+ ++VR P GPP + +E + +T+V + W S H I Y
Sbjct: 686 AHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQ 745
Query: 639 IQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNR 698
+ + + + + ++ + L P Y V A T G G S P
Sbjct: 746 VTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKI- 804
Query: 699 IKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPFD-------- 750
+ T GA P P+ + N L + W P +E G GY + + D
Sbjct: 805 VTTTGAVPG-RPTMMISTTAMNTAL-LQWHP-PKELP-GELLGYRLQYCRADEARPNTID 860
Query: 751 -GEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPS 809
G++ + TVT +HK T + ++ A N G G I + +D PS
Sbjct: 861 FGKDDQHFTVTG------LHK------GTTYIFRLAAKNRAGLGE-EFEKEIRTPEDLPS 907
Query: 810 EAPTEVGVKVLSSSEISVHWEHVLEKIVESYQIRYWAAHDKEEAANRVQVTSQEYSARLE 869
P + V L++S + W+ + I Y + +Q + + L
Sbjct: 908 GFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITTDTRFTLT 967
Query: 870 NLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVV 929
L PDT Y I+V A S G GP S I++ T + + +++W+ V
Sbjct: 968 GLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWE--V 1025
Query: 930 ALSNESTVTGYKVLYRPDGQHDGKLYSTHKHSIE---VPIPRDGEYVVEVRAHSDGGDGV 986
S +S V +K+LY +G+ HS+ + + EY + G+
Sbjct: 1026 PDSYKSAVP-FKILY------NGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGL 1078
Query: 987 VSQVKISGAPTLSP 1000
V I AP L P
Sbjct: 1079 QHLVSIRTAPDLLP 1092
Score = 62.8 bits (151), Expect = 2e-09
Identities = 53/172 (30%), Positives = 81/172 (47%), Gaps = 20/172 (11%)
Query: 257 QNVTLECFALGNPVPDIRWRK---VLEPMPSTAEIST--SGAVLKIFNIQLEDEGIYECE 311
+ T+ C A GNP P+I W K ++P S I SGA L+I + + D+G YEC
Sbjct: 150 RTATMLCAAGGNPDPEISWFKDFLPVDPATSNGRIKQLRSGA-LQIESSEESDQGKYECV 208
Query: 312 AENIRG-KDKHQARIYVQA---FPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKN 367
A N G + A +YV+ P + + EV G + CVA G P+P ++W+
Sbjct: 209 ATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMG 268
Query: 368 GYAYHKGE--------LRLYDVTFENAGMYQCIAENTYGAIYANAELKILAL 411
K + L L +V + Y C+A ++ G I A A++ + AL
Sbjct: 269 AEELTKEDEMPVGRNVLELSNVV--RSANYTCVAISSLGMIEATAQVTVKAL 318
>gi|28373124 contactin 4 isoform b precursor [Homo sapiens]
Length = 282
Score = 198 bits (504), Expect = 2e-50
Identities = 97/239 (40%), Positives = 145/239 (60%), Gaps = 3/239 (1%)
Query: 754 WKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPT 813
W + + D RYV ++E++ P + F+VKV FNNKG+GP+S V+ SA++ P++ P
Sbjct: 3 WMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPA 62
Query: 814 EVGVKVLSSSEISVHWEHVLEKI---VESYQIRYWAAHDKEEAANRVQVTSQEYSARLEN 870
+ + LS+++I V W LEK ++ Y+++YW DKEE A +++ + S ++ N
Sbjct: 63 SIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITN 122
Query: 871 LLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVA 930
L Y + V A NSAG GP S + T+K PPSQPP I S S+ I+ WD V A
Sbjct: 123 LKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKA 182
Query: 931 LSNESTVTGYKVLYRPDGQHDGKLYSTHKHSIEVPIPRDGEYVVEVRAHSDGGDGVVSQ 989
L NES V GYKVLYR + Q + T+K S+E+ +P D +Y++E++ SDGGDG S+
Sbjct: 183 LDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSE 241
>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
sapiens]
Length = 2113
Score = 197 bits (502), Expect = 3e-50
Identities = 218/912 (23%), Positives = 358/912 (39%), Gaps = 79/912 (8%)
Query: 61 VSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMVG---GNLVINNPDKQKDAGIYYCLAS 117
V L+C SP +W N ++ L + S+ G L+I + K +G Y C A+
Sbjct: 392 VILSCALTGSPEFTIRWYRNT-ELVLPDEAISIRGLSNETLLITSAQKSH-SGAYQCFAT 449
Query: 118 NNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEF 177
A ++ P E V G+ L+C P ++ W L++
Sbjct: 450 RK-AQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVT--WALDDE 506
Query: 178 PVF---------ITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIP 228
P+ TM +S N + + D G Y C + +
Sbjct: 507 PIVRDGSHRTNQYTMSDGTTISHMN----VTGPQIRDGGVYRCTARN----------LVG 552
Query: 229 LIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPST-AE 287
R P I +++ A+ G++ + C +G P I+W K +P +
Sbjct: 553 SAEYQARINVRGPPSIRAM-RNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQ 611
Query: 288 ISTSGAVLKIFNIQLE-DEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGS 346
+ LK+ ++Q DEG Y C Q+ P ++ IG
Sbjct: 612 VVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASIGQ 671
Query: 347 DLYWPCVATGKPIPT-IRWLKNGYAYHKGE------------LRLYDVTFENAGMYQCIA 393
LY PCV + +P I W K+G G L++ V+ ++ G Y CIA
Sbjct: 672 LLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIA 731
Query: 394 ENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSW--SKG 451
N + +L I+ + P F + P + + K G ++ C P PK W +KG
Sbjct: 732 SNAAATVSRERQL-IVRVPPRFVVQPNNQDGIYGKAG--VLNCSVDGYPPPKVMWKHAKG 788
Query: 452 T------EWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPT 505
+ + + RI I + SL I ++ D G Y C A N G S +
Sbjct: 789 SGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIP 848
Query: 506 RIILAPINADITV-GENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDS 564
+I + N I + G + C A + + + W VID ++ +
Sbjct: 849 AMITSHPNTTIAIKGHAKELNCTARGERPIIIR--WEKGDTVIDPDRV---MRYAIATKD 903
Query: 565 NGELLIRNAQLKHAGR-----YTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATS 619
NG+ ++ +LK A R ++C A L V+ PP PP L I +++A S
Sbjct: 904 NGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPPE-LEIREVKARS 962
Query: 620 VALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEF 679
+ L W++ D +S I+ + I+ K SD W D K I + A VDL P Y
Sbjct: 963 MNLRWTQRFDGNSIITGFDIEYKN-KSDSW-DFKQSTRNISPTINQANIVDLHPASVYSI 1020
Query: 680 RVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNN 739
R+ + N +GR EPS I T+ AAP+ P DV ++ + +TW +E G
Sbjct: 1021 RMYSFNKIGRSEPS-KELTISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGVI 1079
Query: 740 FGYIVAFKPFD-GEEWKKVTVTNPDTG-RYVHKDETMSPSTAFQVKVKAFNNKGDGPYSL 797
GY + ++ G + V TG V+ + + + V V+AFN G GP S
Sbjct: 1080 RGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSS 1139
Query: 798 VAVINSAQDAPSEAPTEVGVKVLSSSEISVHWEH----VLEKIVESYQIRYWAAHDKEEA 853
+ +D PS+ P V ++S + W L +++ Y++ +W+ + E
Sbjct: 1140 EINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEW 1199
Query: 854 ANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIIS 913
+T+ L + T Y ++V A AG G S ++ TK+ P P I +
Sbjct: 1200 GEMQNITTTRERVELRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKA 1259
Query: 914 SVRSGSRYIITW 925
S S +++W
Sbjct: 1260 VPSSASSVVVSW 1271
Score = 106 bits (265), Expect = 1e-22
Identities = 145/635 (22%), Positives = 229/635 (36%), Gaps = 71/635 (11%)
Query: 3 MWLLVSHLVIISITTCLAEFTWYRRYGHGVSEEDKGFGPIFEEQPINTIYPEESLEGKVS 62
MWL+ L++ S+ H ED G F + + S+ V
Sbjct: 61 MWLVTFLLLLDSL--------------HKARPEDVGTSLYFVNDSLQQVTFSSSVG--VV 104
Query: 63 LNCRARASPFPVYKWRMNNGD--VDLTSDRYSMVGGNLVI--------NNPDKQKDAGIY 112
+ C A SP +W + GD D+ R+ G L + N+ D Y
Sbjct: 105 VPCPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGTLQLYPFSPSAFNSFIHDND---Y 161
Query: 113 YCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSY-R 171
+C A N G +RS + + +P+ + R G V C P + +S
Sbjct: 162 FCTAENAAGKIRSPNIRVKAVFREPYTVRVEDQ-RSMRGNVAVFKCLIPSSVQEYVSVVS 220
Query: 172 WLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDK-GNYSCFVSSPSITKSVFSKFIPLI 230
W E + + RF +G LYI++V+ D Y C ++ S L
Sbjct: 221 W---EKDTVSIIPEHRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSNGARLS 277
Query: 231 PIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPSTAEIST 290
+ P I+ F G V L C A G P+P IRW K P+P+ + +
Sbjct: 278 VTDPAESIP---TILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWTK 334
Query: 291 SGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYW 350
L I +++ ED G Y CE N G + + V + IGS +
Sbjct: 335 RITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVIL 394
Query: 351 PCVATGKPIPTIRWLKNGYAYHKGE-----------LRLYDVTFENAGMYQCIAENTYGA 399
C TG P TIRW +N E L + ++G YQC A
Sbjct: 395 SCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKAQT 454
Query: 400 IYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLV--- 456
A + + P + +K + G + + C K AP P +W+ E +V
Sbjct: 455 AQDFAIIALEDGTPRIVSSFSEK--VVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDG 512
Query: 457 --NSSRILIWEDGSLEINNITR---NDGGIYTCFAENNRGKANSTGTLVITDPTRIILAP 511
+++ + + ++ N+T DGG+Y C A N G A + + P I A
Sbjct: 513 SHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPS-IRAM 571
Query: 512 INADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIR 571
N G + + C P + W + ++ N + ++ NG L +
Sbjct: 572 RNITAVAGRDTLINCRVIGYPYYSIK--WYKDALLLPDNHRQVVFE-------NGTLKLT 622
Query: 572 NAQL-KHAGRYTCTAQTIVDNS-SASADLVVRGPP 604
+ Q G Y C+ S S S + V+ PP
Sbjct: 623 DVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPP 657
Score = 62.0 bits (149), Expect = 3e-09
Identities = 57/241 (23%), Positives = 102/241 (42%), Gaps = 16/241 (6%)
Query: 471 INNITRNDGGIYTCFAENNRGKANSTGTLVITD----PTRIILAPINADITVGENATMQC 526
I ++ R + A + G+ NS+ + I P +II ++ + C
Sbjct: 1312 IAHLNRGQQYLLWVAAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPC 1371
Query: 527 AASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQ 586
+ DPA + + I + + + ++ +NG LL+R + + +G YTCTA
Sbjct: 1372 NSVGDPAPAVKWTKDSEDSAIPVSMDG-----HRLIHTNGTLLLRAVKAEDSGYYTCTAT 1426
Query: 587 TIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILS 646
+ +L+V+ PP P L + A+S+ LTW G + S I + +Q S
Sbjct: 1427 NTGGFDTIIVNLLVQVPPDQP-RLTVSKTSASSITLTWIPGDNGGSSIRGFVLQYSVDNS 1485
Query: 647 DDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAP 706
++WKD I + + + L Y+ ++ A N++G G S KT G P
Sbjct: 1486 EEWKDV-----FISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRIS-EIIEAKTHGREP 1539
Query: 707 N 707
+
Sbjct: 1540 S 1540
Score = 53.5 bits (127), Expect = 1e-06
Identities = 78/316 (24%), Positives = 128/316 (40%), Gaps = 39/316 (12%)
Query: 604 PGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNM 663
PGPP G++ A+SV ++W + + I KYTI + S + P E +
Sbjct: 1251 PGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTIFCSSPGS-----GQPAPSEYETSP 1305
Query: 664 EAA--RAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNR 721
E R L +Y V A + GRG S ++ + A AP+ + GG
Sbjct: 1306 EQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSS---EKVTIEPAGK--APAKIISFGG--- 1357
Query: 722 ELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQ 781
T+T + N+ G P +W K + D+ V D T
Sbjct: 1358 --TVTTPWMKDVRLPCNSVG-----DPAPAVKWTK---DSEDSAIPVSMDGHRLIHTNGT 1407
Query: 782 VKVKAFNNKGDGPYSLVA---------VINSAQDAPSEAPTEVGVKVLSSSEISVHWEHV 832
+ ++A + G Y+ A ++N P + P + V S+S I++ W
Sbjct: 1408 LLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPDQP-RLTVSKTSASSITLTWIPG 1466
Query: 833 LE--KIVESYQIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCG 890
+ + ++Y + D E V ++S E S +L++L T Y +++ A NS G G
Sbjct: 1467 DNGGSSIRGFVLQY--SVDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSG 1524
Query: 891 PPSDMIEAFTKKAPPS 906
S++IEA T PS
Sbjct: 1525 RISEIIEAKTHGREPS 1540
Score = 44.3 bits (103), Expect = 6e-04
Identities = 49/222 (22%), Positives = 90/222 (40%), Gaps = 24/222 (10%)
Query: 754 WKKV-TVTNPD-TGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINS-------- 803
W+K TV +PD RY + +K+K + +GD + INS
Sbjct: 882 WEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPAD-RGDSVFFSCHAINSYGEDRGLI 940
Query: 804 ---AQDAPSEAPTEVGVKVLSSSEISVHWEHVLE--KIVESYQIRYWAAHDK---EEAAN 855
Q+ P P E+ ++ + + +++ W + I+ + I Y D +++
Sbjct: 941 QLTVQEPPD--PPELEIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTR 998
Query: 856 RVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSV 915
+ T + A + +L P + Y I + + N G PS + T++A P PP ++
Sbjct: 999 NISPTINQ--ANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQ 1056
Query: 916 RSGSRYI-ITWDHVVALSNESTVTGYKVLYRPDGQHDGKLYS 956
S+ I +TW + GY++ YR + YS
Sbjct: 1057 PVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYS 1098
Score = 42.0 bits (97), Expect = 0.003
Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 7/98 (7%)
Query: 241 PADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEP------MPSTAEISTSGAV 294
PA I+ V ++V L C ++G+P P ++W K E M I T+G +
Sbjct: 1349 PAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTL 1408
Query: 295 LKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPE 332
L + ++ ED G Y C A N G D + VQ P+
Sbjct: 1409 L-LRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPD 1445
Score = 40.4 bits (93), Expect = 0.009
Identities = 42/175 (24%), Positives = 79/175 (45%), Gaps = 20/175 (11%)
Query: 723 LTITWAPLSREYHYGNNF-GYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQ 781
+T+TW P G++ G+++ + + EEWK V +++ + K +++ T ++
Sbjct: 1459 ITLTWIPGDNG---GSSIRGFVLQYSVDNSEEWKDVFISSSERS---FKLDSLKCGTWYK 1512
Query: 782 VKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVH---WEH---VLEK 835
VK+ A N+ G G S + + PS + + ++S+ ++ W + +
Sbjct: 1513 VKLAAKNSVGSGRISEIIEAKTHGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITA 1572
Query: 836 IVESYQIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCG 890
IV Y+ + A A + +V L L T Y + + ACNSAGCG
Sbjct: 1573 IVLEYRPKGTWAWQGLRANSSGEVF-------LTELREATWYELRMRACNSAGCG 1620
Score = 35.8 bits (81), Expect = 0.21
Identities = 20/65 (30%), Positives = 28/65 (43%), Gaps = 13/65 (20%)
Query: 347 DLYWPCVATGKPIPTIRWLKNG-------------YAYHKGELRLYDVTFENAGMYQCIA 393
D+ PC + G P P ++W K+ + G L L V E++G Y C A
Sbjct: 1366 DVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTA 1425
Query: 394 ENTYG 398
NT G
Sbjct: 1426 TNTGG 1430
Score = 35.8 bits (81), Expect = 0.21
Identities = 36/154 (23%), Positives = 57/154 (37%), Gaps = 37/154 (24%)
Query: 432 VIIECKPKAAPKPKFSWSKGTEW----LVNSSRILIWEDGSLEINNITRNDGGIYTCFAE 487
V + C P P W+K +E + LI +G+L + + D G YTC A
Sbjct: 1367 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTAT 1426
Query: 488 NNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVW------- 540
N G L++ P P +TV + + A +T W
Sbjct: 1427 NTGGFDTIIVNLLVQVP------PDQPRLTVSKTS----------ASSITLTWIPGDNGG 1470
Query: 541 -SFNGYVIDFNKENIH---------YQRNFMLDS 564
S G+V+ ++ +N +R+F LDS
Sbjct: 1471 SSIRGFVLQYSVDNSEEWKDVFISSSERSFKLDS 1504
Score = 33.5 bits (75), Expect = 1.0
Identities = 24/86 (27%), Positives = 36/86 (41%), Gaps = 10/86 (11%)
Query: 61 VSLNCRARASPFPVYKWRMNNGD----VDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLA 116
V L C + P P KW ++ D V + R G L++ K +D+G Y C A
Sbjct: 1367 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAV-KAEDSGYYTCTA 1425
Query: 117 SNNYGMVRSTEATLSFGYLDPFPPEE 142
+N G T+ L PP++
Sbjct: 1426 TNTGGF-----DTIIVNLLVQVPPDQ 1446
>gi|157311649 neogenin homolog 1 [Homo sapiens]
Length = 1461
Score = 191 bits (484), Expect = 4e-48
Identities = 211/817 (25%), Positives = 330/817 (40%), Gaps = 110/817 (13%)
Query: 181 ITMDKRRFVSQTNGNLYIANVEAS-----DKGNYSCFVSSPSITKSVFSKFIPLIP--IP 233
++ D+R+ + +G+L+I+NV S D+G Y C + S+ ++ S+ LI +P
Sbjct: 96 VSDDRRQLLP--DGSLFISNVVHSKHNKPDEGYYQCVATVESLG-TIISRTAKLIVAGLP 152
Query: 234 ERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMP-STAEISTSG 292
T++P P+ VYA G N L C + VP +RW + +P+ I
Sbjct: 153 RFTSQPEPSS-------VYA--GNNAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPS 203
Query: 293 AVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEV---------D 343
+L I N D G+Y C E+ G K+ + ++ P+ E I+D
Sbjct: 204 GMLVISNATEGDGGLYRCVVES-GGPPKYSDEVELKVLPD-PEVISDLVFLKQPSPLVRV 261
Query: 344 IGSDLYWPCVATGKPIPTIRWLKNGYAYHK-----------GELRLYDVTFENAGMYQCI 392
IG D+ PCVA+G P PTI+W+KN A G L + DVT ++AG Y CI
Sbjct: 262 IGQDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCI 321
Query: 393 AENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGT 452
A+N I A AEL + A P F P I A + ++ EC+ P P W K
Sbjct: 322 ADNGNETIEAQAELTVQA-QPEFLKQPTN--IYAHESMDIVFECEVTGKPTPTVKWVKNG 378
Query: 453 EWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPI 512
+ ++ S I ++ +L++ + ++D G Y C AEN+ G A + L+I + P+
Sbjct: 379 DMVIPSDYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPL 438
Query: 513 NADITVGENATMQCAASFDPALDLTFVWSFNG---------YVIDFNKENIHYQRNFMLD 563
+A AS + W Y + + KE I +R
Sbjct: 439 -------PSAPRDVVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTS 491
Query: 564 SNGELLIRNAQLKHAGRY--TCTAQTIVDNSSASADLVVRGP-----PGPPGGLRIEDIR 616
GE+ + L A Y AQ + +SA L V PGP LR
Sbjct: 492 HPGEMQVTIQNLMPATVYIFRVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAAS 551
Query: 617 ATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWME 676
TS+ +TW + I Y + +D +D ++ + + L + E
Sbjct: 552 PTSITVTWETPVSGNGEIQNYKLYYMEKGTDKEQD-------VDVSSHSYTINGLKKYTE 604
Query: 677 YEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHY 736
Y FRVVA N G G S P ++T P+ AP ++ ++ + I W P +
Sbjct: 605 YSFRVVAYNKHGPG-VSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQN 663
Query: 737 GNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGP-- 794
G GY + ++ VT T + E + T + +V A G GP
Sbjct: 664 GQITGYKIRYR--KASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPAT 721
Query: 795 -YSLVAVINSAQDAP--SEAPTEVGVKVLSSSEISVHWEHVLEK--IVESYQIRYWAAHD 849
+ S D E P+ + V+ L +S I V W + +V Y I Y
Sbjct: 722 DWLSAETFESDLDETRVPEVPSSLHVRPLVTS-IVVSWTPPENQNIVVRGYAIGYGIG-- 778
Query: 850 KEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPP------------SDMIE 897
A ++V ++ +ENL P + Y I + A N+ G G P + ++
Sbjct: 779 -SPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVD 837
Query: 898 AFTKKAP--------PSQPP-RIISSVRSGSRYIITW 925
F AP P PP + +S+ S ITW
Sbjct: 838 LFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITW 874
Score = 176 bits (447), Expect = 8e-44
Identities = 187/799 (23%), Positives = 314/799 (39%), Gaps = 84/799 (10%)
Query: 241 PADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK---VLEPMPSTAEISTSGAVLKI 297
P +V+ D ++ G +V L C A P P I W+K L + L I
Sbjct: 52 PFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFI 111
Query: 298 FNI-----QLEDEGIYECEA--ENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYW 350
N+ DEG Y+C A E++ A++ V P + + V G++
Sbjct: 112 SNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAIL 171
Query: 351 PCVATGKPIPTIRWLKNG---------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIY 401
C +P +RW +N G L + + T + G+Y+C+ E+ Y
Sbjct: 172 NCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNATEGDGGLYRCVVESGGPPKY 231
Query: 402 AN-AELKIL---ALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWL-- 455
++ ELK+L + ++ G V++ C P P W K E L
Sbjct: 232 SDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDT 291
Query: 456 VNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINAD 515
+S R+++ GSLEI+++T +D G Y C A+N + L + + P N
Sbjct: 292 ESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTNIY 351
Query: 516 ITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQL 575
+ +C + P T W NG + + F + L +
Sbjct: 352 AHESMDIVFECEVTGKPT--PTVKWVKNG-------DMVIPSDYFKIVKEHNLQVLGLVK 402
Query: 576 KHAGRYTCTAQTIVDNSSASADLVV-------RGP-PGPPGGLRIEDIRATSVALTW-SR 626
G Y C A+ V N+ A A L++ GP P P + + + LTW +
Sbjct: 403 SDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTP 462
Query: 627 GSDNHSPISKYTI-QTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATN 685
SD H Y++ TK ++ + + + P G M+ +L+P Y FRV+A N
Sbjct: 463 ASDPHGDNLTYSVFYTKEGIARERVENTSHP----GEMQVT-IQNLMPATVYIFRVMAQN 517
Query: 686 TLGRGEPSIP-----SNRIKTDGAAPNVAPSDVGGGGGRNRELTITW-APLSREYHYGNN 739
G GE S P ++ G APN+ +T+TW P+S N
Sbjct: 518 KHGSGESSAPLRVETQPEVQLPGPAPNLR-----AYAASPTSITVTWETPVSGNGEIQNY 572
Query: 740 FGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVA 799
Y + K D E+ + D + + + T + +V A+N G G +
Sbjct: 573 KLYYME-KGTDKEQ-------DVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDV 624
Query: 800 VINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKI----VESYQIRYWAAHDKEEAAN 855
+ + D PS AP + ++V +S I +HW+ + Y+IRY A K +
Sbjct: 625 AVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYRKASRKSDVTE 684
Query: 856 RVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMI--EAFTKKAPPSQPPRIIS 913
+ V+ + S +E L T+Y V A G GP +D + E F ++ P + S
Sbjct: 685 TL-VSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPS 743
Query: 914 SVRSG---SRYIITWDHVVALSNESTVTGYKVLYRPDGQHDGKL---YSTHKHSIEVPIP 967
S+ + +++W + V GY + Y H + Y ++IE P
Sbjct: 744 SLHVRPLVTSIVVSW--TPPENQNIVVRGYAIGYGIGSPHAQTIKVDYKQRYYTIENLDP 801
Query: 968 RDGEYVVEVRAHSDGGDGV 986
YV+ ++A ++ G+G+
Sbjct: 802 -SSHYVITLKAFNNVGEGI 819
Score = 164 bits (415), Expect = 4e-40
Identities = 232/1037 (22%), Positives = 403/1037 (38%), Gaps = 136/1037 (13%)
Query: 43 FEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSD--RYSMVGGNLVI 100
F +P++T+ S V LNC A + P P +W+ + ++L SD R + G+L I
Sbjct: 55 FLVEPVDTLSVRGS---SVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFI 111
Query: 101 NNPDKQK----DAGIYYCLAS-NNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGKGMV 155
+N K D G Y C+A+ + G + S A L L F + P V G +
Sbjct: 112 SNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPS-SVYAGNNAI 170
Query: 156 LLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSS 215
L C+ + RW N P+ + R + +G L I+N D G Y C V S
Sbjct: 171 LNCEVNADLVPFV--RWEQNRQPLLLD---DRVIKLPSGMLVISNATEGDGGLYRCVVES 225
Query: 216 PSITKSVFSKFIPLIPIPERTTKPYPADIVV--QFKDVYALMGQNVTLECFALGNPVPDI 273
K + ++P PE + D+V Q + ++GQ+V L C A G P P I
Sbjct: 226 GGPPKYSDEVELKVLPDPEVIS-----DLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTI 280
Query: 274 RWRK---VLEPMPSTAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAF 330
+W K L+ S + +G L+I ++ +D G Y C A+N + QA + VQA
Sbjct: 281 KWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQ 340
Query: 331 PEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNG---------YAYHKGELRLYDV 381
PE+++ + D+ + C TGKP PT++W+KNG + L++ +
Sbjct: 341 PEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNLQVLGL 400
Query: 382 TFENAGMYQCIAENTYGAIYANAELKILALAP--TFEMNPMKKKILAAKGGRVIIEC--- 436
+ G YQCIAEN G A A+L IL AP T + + ++A+ I+
Sbjct: 401 VKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWR 460
Query: 437 KPKAAPK------PKFSWSKG--TEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAEN 488
P + P F +G E + N+S + + I N+ I+ A+N
Sbjct: 461 TPASDPHGDNLTYSVFYTKEGIARERVENTSHP---GEMQVTIQNLMPATVYIFRVMAQN 517
Query: 489 NRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVID 548
G S+ L + + L G ++ A+ ++ +T+ +G
Sbjct: 518 KHGSGESSAPLRVETQPEVQLP--------GPAPNLRAYAASPTSITVTWETPVSGNGEI 569
Query: 549 FNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSS-----ASADLVVRG- 602
N + + ++ + + ++ + + +YT + +V + ++ D+ VR
Sbjct: 570 QNYKLYYMEKGTDKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTL 629
Query: 603 ---PPGPPGGLRIEDIRATSVALTWS--RGSDNHSPISKYTIQTKTILSDDWKDAKTDPP 657
P P L +E + S+ + W + + I+ Y I+ + + +
Sbjct: 630 SDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYRKAS----RKSDVTET 685
Query: 658 IIEGNMEAARAVDLIPWMEYEFRVVATNTLGRG-----------EPSIPSNRIKTDGAAP 706
++ G + L EY FRV A G G E + R+ ++
Sbjct: 686 LVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSL 745
Query: 707 NVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGR 766
+V P + ++W P + GY + + G D +
Sbjct: 746 HVRPLVT--------SIVVSWTPPENQNIVVR--GYAIGY----GIGSPHAQTIKVDYKQ 791
Query: 767 YVHKDETMSPSTAFQVKVKAFNNKGDG----------PYSLVA-----VINS-----AQD 806
+ E + PS+ + + +KAFNN G+G P++ + VIN+
Sbjct: 792 RYYTIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDP 851
Query: 807 APSEAPTEVGVKVLSSSEISVHW-EHVLEKIVESYQIRYWAAHDKEEAANRVQ---VTSQ 862
P P V +LS I + W ++ L K + RY+ K + +
Sbjct: 852 TPMMPPVGVQASILSHDTIRITWADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNANAT 911
Query: 863 EYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPR---IISSVRSGS 919
S + L P+T Y V S T + P+ PP+ ++S
Sbjct: 912 TLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKPK 971
Query: 920 RYIITWDHVVALSNESTVTGYKVLYRPDGQ---HDGKLY----STHKHSIEVPIPRDGEY 972
I+ W + + +TGY + Y D HD + + H I+ + D Y
Sbjct: 972 TIIVNWQPPSEANGK--ITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQ-ELTLDTPY 1028
Query: 973 VVEVRAHSDGGDGVVSQ 989
+++A + G G +S+
Sbjct: 1029 YFKIQARNSKGMGPMSE 1045
Score = 96.7 bits (239), Expect = 1e-19
Identities = 202/930 (21%), Positives = 341/930 (36%), Gaps = 129/930 (13%)
Query: 63 LNCRARASPFPVYKWRMNNGDVDLTSDRYSMVGGNLVINNPDKQKDAGIYYCLASNNYGM 122
LNC A P +W N + L + G LVI+N + D G+Y C+ +
Sbjct: 171 LNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNAT-EGDGGLYRCVVESGGPP 229
Query: 123 VRSTEATLSFGYLDP-------FPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLN 175
S E L DP F + P VRV G+ +VL C P + +W+ N
Sbjct: 230 KYSDEVELKV-LPDPEVISDLVFLKQPSPLVRVI-GQDVVLPCVAS-GLPTP-TIKWMKN 285
Query: 176 EFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITKSVFSKFIPLIPIPER 235
E T R V G+L I++V D G Y C + + T + E
Sbjct: 286 E-EALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQA---------EL 335
Query: 236 TTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPM-PSTAEISTSGAV 294
T + P + + Q ++YA ++ EC G P P ++W K + + PS
Sbjct: 336 TVQAQP-EFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHN 394
Query: 295 LKIFNIQLEDEGIYECEAENIRGKDKHQARIYV-QAFPEWVEHINDTEVDIGSDLY---- 349
L++ + DEG Y+C AEN G + A++ + + P + D+ + L
Sbjct: 395 LQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRF 454
Query: 350 ----WPCVAT---GKPIP-TIRWLKNGYAY-------HKGELRLYDVTFEN-----AGMY 389
W A+ G + ++ + K G A H GE++ VT +N ++
Sbjct: 455 IKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQ---VTIQNLMPATVYIF 511
Query: 390 QCIAENTYGAIYANAELKILALAPTFEMNPMKK-KILAAKGGRVIIECKPKAAPKPK--- 445
+ +A+N +G+ ++A L++ P + AA + + + + +
Sbjct: 512 RVMAQNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPTSITVTWETPVSGNGEIQN 571
Query: 446 ---FSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVIT 502
+ KGT+ + + S IN + + + A N G ST + +
Sbjct: 572 YKLYYMEKGTD----KEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVR 627
Query: 503 DPTRI-ILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFM 561
+ + AP N + V + ++ + P T GY I + K +
Sbjct: 628 TLSDVPSAAPQNLSLEVRNSKSIMI--HWQPPAPATQNGQITGYKIRYRKASRKSDVTET 685
Query: 562 LDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASA-----------DLVVRGPPGPPGGL 610
L S +L L Y + N + A DL P P L
Sbjct: 686 LVSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSL 745
Query: 611 RIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVD 670
+ + TS+ ++W+ + + + Y I I S + K D +E +
Sbjct: 746 HVRPL-VTSIVVSWTPPENQNIVVRGYAIGYG-IGSPHAQTIKVDYKQRYYTIE-----N 798
Query: 671 LIPWMEYEFRVVATNTLGRGEPSIPS--NRIKTDGA-----------------APNVAPS 711
L P Y + A N +G G P S R TD + P + P
Sbjct: 799 LDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFVINAPYTPVPDPTPMMPPV 858
Query: 712 DVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTN-PDTGRYVHK 770
V + + ITWA S H + + WK TN P +Y +
Sbjct: 859 GVQASILSHDTIRITWADNSLPKHQK------ITDSRYYTVRWK----TNIPANTKYKNA 908
Query: 771 DET--------MSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGV--KVL 820
+ T + P+T ++ V + +S+ A + + P+ P +V V K
Sbjct: 909 NATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEG 968
Query: 821 SSSEISVHWEHVLEKI--VESYQIRYWAAHDKEEAANRV--QVTSQEYSARLENLLPDTQ 876
I V+W+ E + Y I Y++ E + V V + +++ L DT
Sbjct: 969 KPKTIIVNWQPPSEANGKITGYII-YYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTP 1027
Query: 877 YFIEVGACNSAGCGPPSDMIEAFTKKAPPS 906
Y+ ++ A NS G GP S+ ++ T KA S
Sbjct: 1028 YYFKIQARNSKGMGPMSEAVQFRTPKADSS 1057
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform
2 precursor [Homo sapiens]
Length = 1899
Score = 184 bits (466), Expect = 5e-46
Identities = 179/674 (26%), Positives = 280/674 (41%), Gaps = 75/674 (11%)
Query: 352 CVATGKPIPTIRWLKNGYAYHKGELRLYDV--------------TFENAGMYQCIAENTY 397
C ATG P P I W K G + + T + +Y+C+A N
Sbjct: 45 CQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIYECVASNNV 104
Query: 398 GAIYANAELKILAL------APTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKG 451
G I + L +L PT +M P K + + ++ C P P+ +W K
Sbjct: 105 GEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATML--CAASGNPDPEITWFKD 162
Query: 452 ---TEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTG----TLVITDP 504
+ N+ RI G+L+I +D G Y C A N+ G S V P
Sbjct: 163 FLPVDTSNNNGRIKQLRSGALQIEQSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVP 222
Query: 505 TRIILAPINADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDS 564
R + P N +I G + + C A P + +V G ++++ RN +L+
Sbjct: 223 PRFSIPPTNHEIMPGGSVNITCVAVGSP---MPYVKWMLGAEDLTPEDDMPIGRN-VLEL 278
Query: 565 NGELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRATSVALTW 624
N ++ + YTC A + + A A + V+ P PPG + + ATS+ LTW
Sbjct: 279 N--------DVRQSANYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTW 330
Query: 625 SRGSDNHSPISKYTIQTKTILSDD-WKDAKTDPPIIEGNMEAARAV-DLIPWMEYEFRVV 682
G N P+S Y IQ K S++ +K+ I+G +V L P+ +YEFRVV
Sbjct: 331 DSG--NPEPVSYYIIQHKPKNSEELYKE-------IDGVATTRYSVAGLSPYSDYEFRVV 381
Query: 683 ATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGY 742
A N +GRG PS P +T AP+ AP DV + + + W E G GY
Sbjct: 382 AVNNIGRGPPSEPV-LTQTSEQAPSSAPRDVQARMLSSTTILVQWK--EPEEPNGQIQGY 438
Query: 743 IVAFKPFDGE---EWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVA 799
V + + W K V + + + P + VKV AF + GDGP S
Sbjct: 439 RVYYTMDPTQHVNNWMKHNVADSQ----ITTIGNLVPQKTYSVKVLAFTSIGDGPLSSDI 494
Query: 800 VINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIVESYQIRYWAAHDKEEAANRVQV 859
+ + P + P + S + I + W + +Y++ Y EE ++
Sbjct: 495 QVITQTGVPGQ-PLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGEHGEEQRITIEP 553
Query: 860 TSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVR-SG 918
+ S RL+ L P++ Y+ + A + G G + I A T ++ PS PP+ IS S
Sbjct: 554 GT---SYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSS 610
Query: 919 SRYIITWDHVVALSNESTVTGYKVLYRP-DGQHD------GKLYSTHKHSIEVPIPRDGE 971
+ +++W +T Y + Y DG+ D G T K+ +E + + E
Sbjct: 611 TSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLE-QLEKWTE 669
Query: 972 YVVEVRAHSDGGDG 985
Y + V AH+D G G
Sbjct: 670 YRITVTAHTDVGPG 683
Score = 131 bits (329), Expect = 4e-30
Identities = 186/837 (22%), Positives = 318/837 (37%), Gaps = 134/837 (16%)
Query: 250 DVYALMGQNVTLECFALGNPVPDIRW----RKVLEPMPSTAEIST-SGAVLKIFNIQL-E 303
D + G + C A G+P P I W +KV E SG+VL+I ++
Sbjct: 32 DQTGVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPR 91
Query: 304 DEGIYECEAENIRGKDKHQARIYV-------QAFPEWVEHINDTEVDIGSDL-------- 348
DE IYEC A N G+ R+ V + FP +D+G L
Sbjct: 92 DEAIYECVASNNVGEISVSTRLTVLREDQIPRGFP---------TIDMGPQLKVVERTRT 142
Query: 349 -YWPCVATGKPIPTIRWLK----------NG--YAYHKGELRLYDVTFENAGMYQCIAEN 395
C A+G P P I W K NG G L++ + G Y+C+A N
Sbjct: 143 ATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSGALQIEQSEESDQGKYECVATN 202
Query: 396 TYGAIY---ANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGT 452
+ G Y AN +++ + P F + P +I+ GG V I C +P P W G
Sbjct: 203 SAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIM--PGGSVNITCVAVGSPMPYVKWMLGA 260
Query: 453 EWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPI 512
E L + I + LE+N++ ++ YTC A + G + + + + + P
Sbjct: 261 EDLTPEDDMPIGRN-VLELNDVRQSAN--YTCVAMSTLGVIEAIAQITV----KALPKPP 313
Query: 513 NADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRN 572
+ AT +T W N E + Y N E L +
Sbjct: 314 GTPVVTESTAT-----------SITLTWDSG------NPEPVSYYIIQHKPKNSEELYKE 356
Query: 573 AQLKHAGRYTCTAQTIVDNSS---ASADLVVRGPP--------------GPPGGLRIEDI 615
RY+ + + + + + RGPP P ++ +
Sbjct: 357 IDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARML 416
Query: 616 RATSVALTWSRGSDNHSPISKYTI---QTKTILSDDWKDAKTDPPIIEGNMEAARAVDLI 672
+T++ + W + + I Y + T ++W + + +L+
Sbjct: 417 SSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNV------ADSQITTIGNLV 470
Query: 673 PWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSR 732
P Y +V+A ++G G P ++ T P P + + ++W P R
Sbjct: 471 PQKTYSVKVLAFTSIGDG-PLSSDIQVITQTGVPG-QPLNFKAEPESETSILLSWTP-PR 527
Query: 733 EYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGD 792
N Y + +K + E +++T+ P T ++ + + P++ + ++ A + +G
Sbjct: 528 SDTIAN---YELVYKDGEHGEEQRITI-EPGTS---YRLQGLKPNSLYYFRLAARSPQGL 580
Query: 793 GPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWE-HVLEK---IVESYQIRYWAAH 848
G + + Q PS P ++ SS+ I V W+ +EK I+ Y I+Y A
Sbjct: 581 GASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVD 640
Query: 849 DKEEAANRV-QVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQ 907
+++ + + + S LE L T+Y I V A G GP S + T + PS
Sbjct: 641 GEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSG 700
Query: 908 PPRIISSVRSGSRYI-ITWDHVVALSNESTVTGYKVLY------RPDGQ----------H 950
PPR + S + ++W V + GY+V Y P GQ
Sbjct: 701 PPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADA 760
Query: 951 DGKLYSTHKHSIEVP-IPRDGEYVVEVRAHSDGGDGVVSQVKI---SGAPTLSPSLL 1003
+ T +H + + + + Y + V A++ GDG S+ K+ +GA P L+
Sbjct: 761 QWEFDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLV 817
Score = 122 bits (307), Expect = 1e-27
Identities = 180/789 (22%), Positives = 304/789 (38%), Gaps = 82/789 (10%)
Query: 257 QNVTLECFALGNPVPDIRWRKVLEPMPSTAEIST-----SGAVLKIFNIQLEDEGIYECE 311
+ T+ C A GNP P+I W K P+ ++ SGA L+I + D+G YEC
Sbjct: 141 RTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRSGA-LQIEQSEESDQGKYECV 199
Query: 312 AENIRG-KDKHQARIYVQAF---PEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWL-- 365
A N G + A +YV+ P + + E+ G + CVA G P+P ++W+
Sbjct: 200 ATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSPMPYVKWMLG 259
Query: 366 ------KNGYAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNP 419
++ + L L DV + Y C+A +T G I A A++ + AL P
Sbjct: 260 AEDLTPEDDMPIGRNVLELNDV--RQSANYTCVAMSTLGVIEAIAQITVKALP-----KP 312
Query: 420 MKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDG----SLEINNIT 475
++ I P+P S+ NS + DG + ++
Sbjct: 313 PGTPVVTESTATSITLTWDSGNPEP-VSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLS 371
Query: 476 RNDGGIYTCFAENNRGKAN-STGTLVITDPTRIILAP--INADITVGENATMQCAASFDP 532
+ A NN G+ S L T AP + A + +Q +P
Sbjct: 372 PYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEP 431
Query: 533 ALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGE---LLIRNAQLKHAGRYTCTAQTIV 589
+ GY + + + + N+M + + I N + A T +
Sbjct: 432 NGQI------QGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSI 485
Query: 590 DNSSASADLVV---RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSPISKYTIQTKTILS 646
+ S+D+ V G PG P + E TS+ L+W+ P TI ++
Sbjct: 486 GDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWT-------PPRSDTIANYELVY 538
Query: 647 DDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAP 706
D + + IE + R L P Y FR+ A + G G S +T + P
Sbjct: 539 KDGEHGEEQRITIEPGT-SYRLQGLKPNSLYYFRLAARSPQGLGA-STAEISARTMQSKP 596
Query: 707 NVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTN--PDT 764
+ P D+ + + ++W P E G Y + + DGE+ K + DT
Sbjct: 597 SAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDT 656
Query: 765 GRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSE 824
+Y+ E + T +++ V A + G GP SL +I + +D PS P +V V+ ++S+
Sbjct: 657 TKYLL--EQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTS 714
Query: 825 ISVHWEHVLEK----IVESYQIRYWAAHDKEEAANRVQV------------TSQEYSARL 868
+ V W + + YQ+ Y + E + + E+ +
Sbjct: 715 VKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWEFDDTTEHDMII 774
Query: 869 ENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHV 928
L P+T Y + V A + G G S T A P +P +I+ + + +I W
Sbjct: 775 SGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTA-LIQWHPP 833
Query: 929 VALSNESTVTGYKVLY-RPDGQHDGKLYSTHK--HSIEVPIPRDGEYVVEVRAHSDGGDG 985
V + GY++ + R D + L + K H I + YV + A + G G
Sbjct: 834 V--DTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFG 891
Query: 986 --VVSQVKI 992
+V ++ I
Sbjct: 892 EEMVKEISI 900
Score = 120 bits (301), Expect = 7e-27
Identities = 150/584 (25%), Positives = 239/584 (40%), Gaps = 110/584 (18%)
Query: 413 PTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEWLVNSS-RILIWEDGSLEI 471
P F P+ + GG C+ P+PK W+K + + N ++ ++DGS +
Sbjct: 24 PRFTRTPVDQT--GVSGGVASFICQATGDPRPKIVWNKKGKKVSNQRFEVIEFDDGSGSV 81
Query: 472 NNI----TRNDGGIYTCFAENNRGKAN-STGTLVITD-------PTRIILAPINADITVG 519
I T D IY C A NN G+ + ST V+ + PT I + P +
Sbjct: 82 LRIQPLRTPRDEAIYECVASNNVGEISVSTRLTVLREDQIPRGFPT-IDMGPQLKVVERT 140
Query: 520 ENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAG 579
ATM CAAS +P ++T+ F N I R+ G L I ++ G
Sbjct: 141 RTATMLCAASGNPDPEITWFKDFLPVDTSNNNGRIKQLRS------GALQIEQSEESDQG 194
Query: 580 RYTCTAQTIVDNS-SASADLVVRG---PPG---PPGGLRIE---DIRATSVALTWSRGSD 629
+Y C A SA A+L VR PP PP I + T VA+
Sbjct: 195 KYECVATNSAGTRYSAPANLYVRVRRVPPRFSIPPTNHEIMPGGSVNITCVAV------G 248
Query: 630 NHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLG- 688
+ P K+ + + + +D D ++E N A + VA +TLG
Sbjct: 249 SPMPYVKWMLGAEDLTPED--DMPIGRNVLELNDVRQSA---------NYTCVAMSTLGV 297
Query: 689 ---------RGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSRE-YHYGN 738
+ P P + T+ A ++ T+TW + E Y
Sbjct: 298 IEAIAQITVKALPKPPGTPVVTESTATSI---------------TLTWDSGNPEPVSY-- 340
Query: 739 NFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLV 798
YI+ KP + EE K + T RY +SP + ++ +V A NN G GP S
Sbjct: 341 ---YIIQHKPKNSEELYK-EIDGVATTRY--SVAGLSPYSDYEFRVVAVNNIGRGPPSEP 394
Query: 799 AVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEK--IVESYQIRY----------WA 846
+ +++ APS AP +V ++LSS+ I V W+ E ++ Y++ Y W
Sbjct: 395 VLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWM 454
Query: 847 AHDKEEAANRVQVTSQEYSARLENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPS 906
H+ ++ Q+T+ + NL+P Y ++V A S G GP S I+ T+ P
Sbjct: 455 KHNVADS----QITT------IGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPG 504
Query: 907 QPPRIISSVRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQH 950
QP + S + +++W T+ Y+++Y+ DG+H
Sbjct: 505 QPLNFKAEPESETSILLSW----TPPRSDTIANYELVYK-DGEH 543
Score = 68.9 bits (167), Expect = 2e-11
Identities = 71/287 (24%), Positives = 128/287 (44%), Gaps = 27/287 (9%)
Query: 59 GKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMV------GGNLVINNPDKQKDAGIY 112
G S C+A P P W N +++ R+ ++ G L I +D IY
Sbjct: 39 GVASFICQATGDPRPKIVW--NKKGKKVSNQRFEVIEFDDGSGSVLRIQPLRTPRDEAIY 96
Query: 113 YCLASNNYGMVR-STEATLSFGYLDP--FPPEER-PEVRVKEG-KGMVLLCDPPYHFPDD 167
C+ASNN G + ST T+ P FP + P+++V E + +LC + D
Sbjct: 97 ECVASNNVGEISVSTRLTVLREDQIPRGFPTIDMGPQLKVVERTRTATMLCAASGN--PD 154
Query: 168 LSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCFVSSPSITK--SVFSK 225
W + PV + + R +G L I E SD+G Y C ++ + T+ + +
Sbjct: 155 PEITWFKDFLPVDTSNNNGRIKQLRSGALQIEQSEESDQGKYECVATNSAGTRYSAPANL 214
Query: 226 FIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPST 285
++ + +P R + P P + + + G +V + C A+G+P+P ++W E +
Sbjct: 215 YVRVRRVPPRFSIP-PTNHEI-------MPGGSVNITCVAVGSPMPYVKWMLGAEDLTPE 266
Query: 286 AEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPE 332
++ VL++ +++ Y C A + G + A+I V+A P+
Sbjct: 267 DDMPIGRNVLELNDVR--QSANYTCVAMSTLGVIEAIAQITVKALPK 311
Score = 65.9 bits (159), Expect = 2e-10
Identities = 83/417 (19%), Positives = 157/417 (37%), Gaps = 34/417 (8%)
Query: 595 SADLVVRGPPGPPGGLRIEDIRATSVALTWSRG--SDNHSPISKYTIQTKTILSDDWKDA 652
SA + P PP + +TS+ ++W + I++Y+I+ + +D D
Sbjct: 588 SARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGED--DK 645
Query: 653 KTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSD 712
+ I + L W EY V A +G G S+ S I+T+ P+ P
Sbjct: 646 PHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESL-SVLIRTNEDVPSGPPRK 704
Query: 713 VGGGGGRNRELTITW-APLSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNP--------- 762
V + + ++W +P+ + H G GY V + + E K +
Sbjct: 705 VEVEAVNSTSVKVSWRSPVPNKQH-GQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQWE 763
Query: 763 --DTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVL 820
DT + + P T++ + V A+ KGDG S ++++ P + + +
Sbjct: 764 FDDTTEHDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQM 823
Query: 821 SSSEISVHWEHVLEKIVESYQIRYWAAHDKEEAANRVQVTSQEYSARLENLLPDTQYFIE 880
+++ I H ++ Y++++ E ++ + +E ++ Y
Sbjct: 824 NTALIQWHPPVDTFGPLQGYRLKF--GRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFR 881
Query: 881 VGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTGY 940
+ A N G G + ++ P P + S + + ++W V +T Y
Sbjct: 882 LSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKY 941
Query: 941 KVLYRPDGQHDGKLYSTHKHSIEVP---------IPRDGEYVVEVRAHSDGGDGVVS 988
+LYR D + + VP + D Y V+VRAH+ G G S
Sbjct: 942 TLLYR-----DINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYS 993
Score = 48.1 bits (113), Expect = 4e-05
Identities = 85/399 (21%), Positives = 139/399 (34%), Gaps = 41/399 (10%)
Query: 567 ELLIRNAQLKHAGRYTCTAQTIVDNSSASADLVVRGPPGPPGGLR--IEDIRATSVALTW 624
+++I Q + + T TA T + + S +V PG R I + + + W
Sbjct: 771 DMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHTQMNTALIQW 830
Query: 625 SRGSDNHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAA-RAVDLIPWMEYEFRVVA 683
D P+ Y ++ KD + + E A D+ Y FR+ A
Sbjct: 831 HPPVDTFGPLQGYRLKFGR------KDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSA 884
Query: 684 TNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYI 743
N +G GE + I + P P ++ G + + ++W P G Y
Sbjct: 885 RNKVGFGEEMVKEISIPEE--VPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYT 942
Query: 744 VAFKPFDGEEWKKVTVTNPDTGRYVHKDETMS-----PSTAFQVKVKAFNNKGDGPYSLV 798
+ ++ + P V D TM+ P T + VKV+A +KG GPYS
Sbjct: 943 LLYRDIN-------IPLLPMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYS-P 994
Query: 799 AVINSAQDAPSEAPTEVGVKVLSSSEISVHWEHVLEKIVESYQIRYWAAHDKEEAANRVQ 858
+V VK + + + + WE I E+Y ++ +
Sbjct: 995 SVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWE-----IPENYNSAMPFKILYDDGKMVEE 1049
Query: 859 VTSQEYSARLENLLPDTQY-FIEVGACNSAGCGPPSDMIEAFTKKAPPS---QPPRIISS 914
V + + NL P+ Y F+ NSAG + T K P P I
Sbjct: 1050 VDGRATQKLIVNLKPEKSYSFVLTNRGNSAG-----GLQHRVTAKTAPDVLRTKPAFIGK 1104
Query: 915 VRSGSRYIITWDHVVALSNESTVTGYKVLYRPDGQHDGK 953
+ V A N + GY ++ P + GK
Sbjct: 1105 TNLDGMITVQLPEVPANEN---IKGYYIIIVPLKKSRGK 1140
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,675,375
Number of Sequences: 37866
Number of extensions: 2101401
Number of successful extensions: 16579
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 267
Number of HSP's successfully gapped in prelim test: 237
Number of HSP's that attempted gapping in prelim test: 6029
Number of HSP's gapped (non-prelim): 4242
length of query: 1018
length of database: 18,247,518
effective HSP length: 112
effective length of query: 906
effective length of database: 14,006,526
effective search space: 12689912556
effective search space used: 12689912556
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.