Guide to the Human Genome
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Search of human proteins with 28372523

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28372523 intraflagellar transport protein IFT20 [Homo
sapiens]
         (148 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28372523 intraflagellar transport protein IFT20 [Homo sapiens]     292   8e-80
gi|78000165 sorbin and SH3 domain containing 1 isoform 4 [Homo s...    55   2e-08
gi|148839316 NIMA-related kinase 4 [Homo sapiens]                      54   4e-08
gi|6005810 mitogen-activated protein kinase kinase kinase kinase...    54   5e-08
gi|219881538 hypothetical protein LOC199870 isoform 2 [Homo sapi...    52   1e-07
gi|219881536 hypothetical protein LOC199870 isoform 1 [Homo sapi...    52   1e-07
gi|231571356 nitric oxide synthase 3 isoform 4 [Homo sapiens]          52   2e-07
gi|58533176 zinc finger, matrin type 1 isoform 1 [Homo sapiens]        51   3e-07
gi|34147532 myosin, light chain 10, regulatory [Homo sapiens]          49   1e-06
gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo ...    49   2e-06
gi|118442834 RPGRIP1-like isoform a [Homo sapiens]                     48   3e-06
gi|170932471 hypothetical protein LOC79703 [Homo sapiens]              46   1e-05
gi|239735607 nucleoredoxin-like 2 isoform 2 [Homo sapiens]             46   1e-05
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]     46   1e-05
gi|148236061 hypothetical protein LOC285501 [Homo sapiens]             45   2e-05
gi|61969666 arginine-fifty homeobox [Homo sapiens]                     45   3e-05
gi|94680985 cyclin J-like [Homo sapiens]                               44   4e-05
gi|239744440 PREDICTED: hypothetical protein XP_002343124 [Homo ...    43   8e-05
gi|58294160 breast carcinoma amplified sequence 4 isoform a [Hom...    43   8e-05
gi|34147403 intraflagellar transport 81-like isoform 2 [Homo sap...    43   1e-04
gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1 [...    42   1e-04
gi|58331120 hypothetical protein LOC29058 isoform 1 [Homo sapiens]     42   1e-04
gi|239755619 PREDICTED: hypothetical protein [Homo sapiens]            42   2e-04
gi|239750132 PREDICTED: hypothetical protein XP_002347267 [Homo ...    42   2e-04
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]       42   2e-04
gi|154146187 TFIIS central domain-containing protein 1 [Homo sap...    42   2e-04
gi|237858664 hypothetical protein LOC123207 isoform b [Homo sapi...    42   2e-04
gi|24497440 interleukin 12 receptor, beta 1 isoform 2 precursor ...    42   2e-04
gi|187608508 centromere protein L isoform 1 [Homo sapiens]             41   3e-04
gi|122939204 parkin co-regulated gene protein isoform 1 [Homo sa...    39   0.002

>gi|28372523 intraflagellar transport protein IFT20 [Homo sapiens]
          Length = 148

 Score =  292 bits (747), Expect = 8e-80
 Identities = 148/148 (100%), Positives = 148/148 (100%)

Query: 1   MAKDILGEAGLHFDELNKLRVLDPEVTQQTIELKEECKDFVDKIGQFQKIVGGLIELVDQ 60
           MAKDILGEAGLHFDELNKLRVLDPEVTQQTIELKEECKDFVDKIGQFQKIVGGLIELVDQ
Sbjct: 1   MAKDILGEAGLHFDELNKLRVLDPEVTQQTIELKEECKDFVDKIGQFQKIVGGLIELVDQ 60

Query: 61  LAKEAENEKMKSLAVSPRLECTGAISAHCKLCLSDSSDSPTSPSRVGGTTGHRCSELAQI 120
           LAKEAENEKMKSLAVSPRLECTGAISAHCKLCLSDSSDSPTSPSRVGGTTGHRCSELAQI
Sbjct: 61  LAKEAENEKMKSLAVSPRLECTGAISAHCKLCLSDSSDSPTSPSRVGGTTGHRCSELAQI 120

Query: 121 YSKAERSSTAATSSPNSRKENAARKVSG 148
           YSKAERSSTAATSSPNSRKENAARKVSG
Sbjct: 121 YSKAERSSTAATSSPNSRKENAARKVSG 148


>gi|78000165 sorbin and SH3 domain containing 1 isoform 4 [Homo
           sapiens]
          Length = 1151

 Score = 55.1 bits (131), Expect = 2e-08
 Identities = 33/75 (44%), Positives = 45/75 (60%), Gaps = 2/75 (2%)

Query: 67  NEKMKSLAV-SPRLECTGAISAHCKLCLSDSSDSPTSPSRVGGTTGHRCSELAQIYSKAE 125
           +E+ KS +V SPRLEC+G + AHC L L DSS+ PTS S+V GT        +  YS +E
Sbjct: 431 SEETKSCSVMSPRLECSGTVIAHCSLKLLDSSNPPTSASQVAGTADDDSDLYSPRYSFSE 490

Query: 126 RSSTAATSSPNSRKE 140
             + +  S P S+ E
Sbjct: 491 -DTKSPLSVPRSKSE 504


>gi|148839316 NIMA-related kinase 4 [Homo sapiens]
          Length = 841

 Score = 54.3 bits (129), Expect = 4e-08
 Identities = 30/57 (52%), Positives = 38/57 (66%), Gaps = 1/57 (1%)

Query: 55  IELVDQLAKEAENEKMKSLAVSPRLECTGAISAHCKLCLSDSSDSPTSPSRVGGTTG 111
           ++ +  L KE +  K +SLA+SP+LEC+G I AH  L L  SSDSP S SRV G TG
Sbjct: 441 VKPLQPLIKE-QKPKDQSLALSPKLECSGTILAHSNLRLLGSSDSPASASRVAGITG 496


>gi|6005810 mitogen-activated protein kinase kinase kinase kinase 1
           isoform 2 [Homo sapiens]
          Length = 833

 Score = 53.9 bits (128), Expect = 5e-08
 Identities = 29/54 (53%), Positives = 34/54 (62%), Gaps = 1/54 (1%)

Query: 59  DQLAKEAENEKMK-SLAVSPRLECTGAISAHCKLCLSDSSDSPTSPSRVGGTTG 111
           DQL +E  +  +   L  SPRLEC+G IS HC L L  SS+SP S SRV G TG
Sbjct: 779 DQLLQELRDPTLTFRLLGSPRLECSGTISPHCNLLLPGSSNSPASASRVAGITG 832


>gi|219881538 hypothetical protein LOC199870 isoform 2 [Homo
           sapiens]
          Length = 312

 Score = 52.4 bits (124), Expect = 1e-07
 Identities = 27/51 (52%), Positives = 31/51 (60%), Gaps = 7/51 (13%)

Query: 78  RLECTGAISAHCKLCLSDSSDSPTSPSRVGGTTG-------HRCSELAQIY 121
           RLEC G ISAHC L L  SSDSP S SRV G TG        +C++  Q+Y
Sbjct: 49  RLECNGTISAHCNLHLPGSSDSPASSSRVAGITGIKTNTICKKCAQNVQLY 99


>gi|219881536 hypothetical protein LOC199870 isoform 1 [Homo
           sapiens]
          Length = 341

 Score = 52.4 bits (124), Expect = 1e-07
 Identities = 27/51 (52%), Positives = 31/51 (60%), Gaps = 7/51 (13%)

Query: 78  RLECTGAISAHCKLCLSDSSDSPTSPSRVGGTTG-------HRCSELAQIY 121
           RLEC G ISAHC L L  SSDSP S SRV G TG        +C++  Q+Y
Sbjct: 49  RLECNGTISAHCNLHLPGSSDSPASSSRVAGITGIKTNTICKKCAQNVQLY 99


>gi|231571356 nitric oxide synthase 3 isoform 4 [Homo sapiens]
          Length = 629

 Score = 51.6 bits (122), Expect = 2e-07
 Identities = 25/44 (56%), Positives = 31/44 (70%)

Query: 68  EKMKSLAVSPRLECTGAISAHCKLCLSDSSDSPTSPSRVGGTTG 111
           E  + L + PRLEC+  I+AHC L L DSS+ PTS S+V GTTG
Sbjct: 581 ENGEGLTLWPRLECSSTITAHCSLNLLDSSNPPTSTSQVVGTTG 624


>gi|58533176 zinc finger, matrin type 1 isoform 1 [Homo sapiens]
          Length = 638

 Score = 51.2 bits (121), Expect = 3e-07
 Identities = 26/41 (63%), Positives = 32/41 (78%), Gaps = 1/41 (2%)

Query: 70  MKSLAVSPRLECTGAISAHCKLCLSDSSDSPTSPSRVGGTT 110
           M+S +V+ RLEC+GAISAHC L L  SSDSP S S++ GTT
Sbjct: 1   MESCSVT-RLECSGAISAHCSLHLPGSSDSPASASQIAGTT 40


>gi|34147532 myosin, light chain 10, regulatory [Homo sapiens]
          Length = 226

 Score = 49.3 bits (116), Expect = 1e-06
 Identities = 24/38 (63%), Positives = 29/38 (76%)

Query: 68  EKMKSLAVSPRLECTGAISAHCKLCLSDSSDSPTSPSR 105
           E  +SLA+SPRLE  G ISAHC LCL+ SS+SP S S+
Sbjct: 54  EFKESLALSPRLERNGMISAHCNLCLTGSSNSPASASQ 91


>gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo
           sapiens]
          Length = 511

 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 26/49 (53%), Positives = 31/49 (63%)

Query: 72  SLAVSPRLECTGAISAHCKLCLSDSSDSPTSPSRVGGTTGHRCSELAQI 120
           +LA+SPRLEC+G ISAHC   L  SS+SP   SRV G   +  S L  I
Sbjct: 137 NLALSPRLECSGKISAHCNPHLQGSSNSPAQASRVAGIYRYTVSFLLVI 185


>gi|118442834 RPGRIP1-like isoform a [Homo sapiens]
          Length = 1315

 Score = 48.1 bits (113), Expect = 3e-06
 Identities = 24/41 (58%), Positives = 28/41 (68%)

Query: 71   KSLAVSPRLECTGAISAHCKLCLSDSSDSPTSPSRVGGTTG 111
            +SLA+SP L C+ AISAHC   L  SSD P S S+V G TG
Sbjct: 1098 QSLALSPGLGCSSAISAHCNFRLPGSSDFPASASQVDGITG 1138


>gi|170932471 hypothetical protein LOC79703 [Homo sapiens]
          Length = 677

 Score = 46.2 bits (108), Expect = 1e-05
 Identities = 23/39 (58%), Positives = 26/39 (66%)

Query: 72  SLAVSPRLECTGAISAHCKLCLSDSSDSPTSPSRVGGTT 110
           SL + PR EC+GA+SAHC L L  SSDS  S  RV G T
Sbjct: 108 SLTLLPRPECSGAVSAHCNLHLPGSSDSHASVPRVAGIT 146


>gi|239735607 nucleoredoxin-like 2 isoform 2 [Homo sapiens]
          Length = 135

 Score = 45.8 bits (107), Expect = 1e-05
 Identities = 20/31 (64%), Positives = 24/31 (77%)

Query: 69  KMKSLAVSPRLECTGAISAHCKLCLSDSSDS 99
           + +SLA+ PRLEC+G I AHC LCL  SSDS
Sbjct: 100 RQRSLALLPRLECSGVILAHCNLCLLGSSDS 130


>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
          Length = 475

 Score = 45.8 bits (107), Expect = 1e-05
 Identities = 24/43 (55%), Positives = 29/43 (67%), Gaps = 1/43 (2%)

Query: 69  KMKSLAVSPRLECTGAISAHCKLCLSDSSDSPTSPSRVGGTTG 111
           + KS +V+ RLEC+G I AHC L L  S DSP S S+  GTTG
Sbjct: 423 RTKSRSVT-RLECSGMILAHCNLRLPGSRDSPASASQAAGTTG 464


>gi|148236061 hypothetical protein LOC285501 [Homo sapiens]
          Length = 109

 Score = 45.4 bits (106), Expect = 2e-05
 Identities = 21/43 (48%), Positives = 27/43 (62%)

Query: 78  RLECTGAISAHCKLCLSDSSDSPTSPSRVGGTTGHRCSELAQI 120
           +LEC+G I AHC LCL  S    TS S+V GTTG +    A++
Sbjct: 21  KLECSGPILAHCNLCLLGSRHPSTSASQVAGTTGEKTMRSARM 63


>gi|61969666 arginine-fifty homeobox [Homo sapiens]
          Length = 315

 Score = 44.7 bits (104), Expect = 3e-05
 Identities = 21/42 (50%), Positives = 27/42 (64%)

Query: 72  SLAVSPRLECTGAISAHCKLCLSDSSDSPTSPSRVGGTTGHR 113
           S  +  +LEC+G +SA+C L L  S+D PTS SRV  TT  R
Sbjct: 35  SFTLLSKLECSGTVSAYCSLNLPGSTDPPTSASRVAATTAIR 76


>gi|94680985 cyclin J-like [Homo sapiens]
          Length = 435

 Score = 44.3 bits (103), Expect = 4e-05
 Identities = 28/69 (40%), Positives = 36/69 (52%), Gaps = 7/69 (10%)

Query: 75  VSPRLECTGAISAHCKLCLSDSSDSPTS-------PSRVGGTTGHRCSELAQIYSKAERS 127
           +SPRL+C+G ISAHC L L  SS+SP S       P +V  TTG        +    + +
Sbjct: 99  LSPRLKCSGMISAHCNLHLPGSSNSPASAPHPPPTPPQVAETTGKFEDREDHVPKLEQIN 158

Query: 128 STAATSSPN 136
           ST   SS N
Sbjct: 159 STRILSSQN 167


>gi|239744440 PREDICTED: hypothetical protein XP_002343124 [Homo
           sapiens]
          Length = 261

 Score = 43.1 bits (100), Expect = 8e-05
 Identities = 22/38 (57%), Positives = 26/38 (68%)

Query: 71  KSLAVSPRLECTGAISAHCKLCLSDSSDSPTSPSRVGG 108
           + LA+ PRLE +G ISA C L L  SSDSP S S+V G
Sbjct: 6   EGLALYPRLEFSGTISARCNLRLLGSSDSPASASQVAG 43


>gi|58294160 breast carcinoma amplified sequence 4 isoform a [Homo
           sapiens]
          Length = 211

 Score = 43.1 bits (100), Expect = 8e-05
 Identities = 28/87 (32%), Positives = 40/87 (45%), Gaps = 12/87 (13%)

Query: 41  VDKIGQFQKIVGGLIELVDQLAKEAENEK------------MKSLAVSPRLECTGAISAH 88
           VD++  F K+VG  +  ++    +AE +                L     +EC+G I A 
Sbjct: 114 VDRLEAFVKMVGHHVAFLEADVLQAERDHGAFPQALRRWLGSAGLPSFRNVECSGTIPAR 173

Query: 89  CKLCLSDSSDSPTSPSRVGGTTGHRCS 115
           C L L  SSDSP S S+V G T   C+
Sbjct: 174 CNLRLPGSSDSPASASQVAGITEVTCT 200


>gi|34147403 intraflagellar transport 81-like isoform 2 [Homo
           sapiens]
          Length = 431

 Score = 42.7 bits (99), Expect = 1e-04
 Identities = 20/39 (51%), Positives = 26/39 (66%)

Query: 66  ENEKMKSLAVSPRLECTGAISAHCKLCLSDSSDSPTSPS 104
           + ++ + L +SPRLEC G I A+C L L  SSD PTS S
Sbjct: 393 KGDERQDLTLSPRLECGGVIMAYCSLKLLGSSDPPTSAS 431


>gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1
          [Homo sapiens]
          Length = 759

 Score = 42.4 bits (98), Expect = 1e-04
 Identities = 19/23 (82%), Positives = 20/23 (86%)

Query: 76 SPRLECTGAISAHCKLCLSDSSD 98
          SPRLEC+GAISAHC L L DSSD
Sbjct: 6  SPRLECSGAISAHCSLHLPDSSD 28


>gi|58331120 hypothetical protein LOC29058 isoform 1 [Homo sapiens]
          Length = 183

 Score = 42.4 bits (98), Expect = 1e-04
 Identities = 22/35 (62%), Positives = 25/35 (71%)

Query: 72  SLAVSPRLECTGAISAHCKLCLSDSSDSPTSPSRV 106
           SL +SPRLE +G ISAHC L L  SSDS  S SR+
Sbjct: 25  SLVLSPRLEPSGVISAHCNLHLLASSDSSASASRL 59


>gi|239755619 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 261

 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 22/38 (57%), Positives = 25/38 (65%)

Query: 71  KSLAVSPRLECTGAISAHCKLCLSDSSDSPTSPSRVGG 108
           + LA  PRLE +G ISA C L L  SSDSP S S+V G
Sbjct: 6   EGLAPYPRLEFSGTISARCNLRLLGSSDSPASASQVAG 43


>gi|239750132 PREDICTED: hypothetical protein XP_002347267 [Homo
           sapiens]
          Length = 261

 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 22/38 (57%), Positives = 25/38 (65%)

Query: 71  KSLAVSPRLECTGAISAHCKLCLSDSSDSPTSPSRVGG 108
           + LA  PRLE +G ISA C L L  SSDSP S S+V G
Sbjct: 6   EGLAPYPRLEFSGTISARCNLRLLGSSDSPASASQVAG 43


>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
          Length = 229

 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 22/34 (64%), Positives = 22/34 (64%)

Query: 78  RLECTGAISAHCKLCLSDSSDSPTSPSRVGGTTG 111
           RL C G ISAH  L L  SSDSP S SRV G TG
Sbjct: 193 RLVCNGVISAHHNLRLWGSSDSPASASRVAGITG 226


>gi|154146187 TFIIS central domain-containing protein 1 [Homo
           sapiens]
          Length = 381

 Score = 42.0 bits (97), Expect = 2e-04
 Identities = 22/40 (55%), Positives = 27/40 (67%)

Query: 85  ISAHCKLCLSDSSDSPTSPSRVGGTTGHRCSELAQIYSKA 124
           ISAH KLCL  SS+SP S  RV GTT  + S+  QI ++A
Sbjct: 2   ISAHRKLCLPGSSNSPASAFRVAGTTAVKMSDKNQIAARA 41


>gi|237858664 hypothetical protein LOC123207 isoform b [Homo
           sapiens]
          Length = 167

 Score = 41.6 bits (96), Expect = 2e-04
 Identities = 19/34 (55%), Positives = 25/34 (73%)

Query: 71  KSLAVSPRLECTGAISAHCKLCLSDSSDSPTSPS 104
           ++LA+SP+LEC+G + AHC L L  SS SP S S
Sbjct: 134 QNLALSPKLECSGVVLAHCNLHLLGSSYSPASAS 167


>gi|24497440 interleukin 12 receptor, beta 1 isoform 2 precursor
           [Homo sapiens]
          Length = 381

 Score = 41.6 bits (96), Expect = 2e-04
 Identities = 20/29 (68%), Positives = 20/29 (68%)

Query: 83  GAISAHCKLCLSDSSDSPTSPSRVGGTTG 111
           G ISAHC L L DS DSP S SRV G TG
Sbjct: 342 GMISAHCNLRLPDSRDSPASASRVAGITG 370


>gi|187608508 centromere protein L isoform 1 [Homo sapiens]
          Length = 390

 Score = 41.2 bits (95), Expect = 3e-04
 Identities = 21/49 (42%), Positives = 28/49 (57%)

Query: 63  KEAENEKMKSLAVSPRLECTGAISAHCKLCLSDSSDSPTSPSRVGGTTG 111
           ++ E   ++ L +SPRLE +G I   C LCL  SSD  T   +V GT G
Sbjct: 132 RDPEAFLVQGLILSPRLEYSGTILVDCNLCLLGSSDPSTLAFQVAGTAG 180


>gi|122939204 parkin co-regulated gene protein isoform 1 [Homo
           sapiens]
          Length = 296

 Score = 38.9 bits (89), Expect = 0.002
 Identities = 19/30 (63%), Positives = 21/30 (70%)

Query: 77  PRLECTGAISAHCKLCLSDSSDSPTSPSRV 106
           PRLEC+GAI A C L    SSD PTS S+V
Sbjct: 210 PRLECSGAIMARCNLDHLGSSDPPTSASQV 239


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.127    0.348 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,255,805
Number of Sequences: 37866
Number of extensions: 215196
Number of successful extensions: 887
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 813
Number of HSP's gapped (non-prelim): 106
length of query: 148
length of database: 18,247,518
effective HSP length: 93
effective length of query: 55
effective length of database: 14,725,980
effective search space: 809928900
effective search space used: 809928900
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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