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Search of human proteins with 28144899
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens]
(536 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens] 1070 0.0
gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens] 1070 0.0
gi|4502011 adenylate kinase 1 [Homo sapiens] 236 4e-62
gi|7706497 UMP-CMP kinase 1 isoform a [Homo sapiens] 132 6e-31
gi|53832001 adenylate kinase 3-like 1 isoform 7 [Homo sapiens] 87 4e-17
gi|53832003 adenylate kinase 3-like 1 isoform 5 [Homo sapiens] 87 4e-17
gi|8051579 adenylate kinase 3-like 1 isoform 6 [Homo sapiens] 87 4e-17
gi|4502013 adenylate kinase 2 isoform a [Homo sapiens] 87 4e-17
gi|7524346 adenylate kinase 2 isoform b [Homo sapiens] 87 4e-17
gi|209915597 UMP-CMP kinase 1 isoform b [Homo sapiens] 77 3e-14
gi|19923437 adenylate kinase 3 [Homo sapiens] 70 6e-12
gi|22749187 putative adenylate kinase-like protein C9orf98 [Homo... 68 2e-11
gi|237858799 adenylate kinase domain containing 1 isoform 1 [Hom... 66 9e-11
gi|21450759 adenylate kinase domain containing 1 isoform 2 [Homo... 42 0.001
gi|7706212 TAF9 RNA polymerase II, TATA box binding protein-asso... 36 0.10
gi|94721261 2',3'-cyclic nucleotide 3' phosphodiesterase [Homo s... 33 0.50
gi|148727333 adenylate kinase 7 [Homo sapiens] 33 0.66
gi|62865612 TAF9 RNA polymerase II, TATA box binding protein-ass... 33 0.86
gi|157388965 schlafen family member 11 [Homo sapiens] 32 1.1
gi|157388963 schlafen family member 11 [Homo sapiens] 32 1.1
gi|157388961 schlafen family member 11 [Homo sapiens] 32 1.1
gi|157388959 schlafen family member 11 [Homo sapiens] 32 1.1
gi|157388957 schlafen family member 11 [Homo sapiens] 32 1.1
gi|56119108 schlafen family member 13 [Homo sapiens] 32 1.1
gi|145580600 schlafen family member 5 [Homo sapiens] 31 2.5
gi|118572599 formin homology 2 domain containing 1 [Homo sapiens] 31 3.3
gi|27501458 CTF18, chromosome transmission fidelity factor 18 ho... 30 4.2
gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens] 30 5.5
gi|169217198 PREDICTED: similar to hCG1644442 [Homo sapiens] 30 5.5
gi|169216377 PREDICTED: similar to hCG1644442 [Homo sapiens] 30 5.5
>gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens]
Length = 562
Score = 1070 bits (2767), Expect = 0.0
Identities = 536/536 (100%), Positives = 536/536 (100%)
Query: 1 MCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPE 60
MCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPE
Sbjct: 27 MCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPE 86
Query: 61 NSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKG 120
NSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKG
Sbjct: 87 NSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKG 146
Query: 121 TQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKL 180
TQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKL
Sbjct: 147 TQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKL 206
Query: 181 MQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDD 240
MQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDD
Sbjct: 207 MQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDD 266
Query: 241 NVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAA 300
NVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAA
Sbjct: 267 NVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAA 326
Query: 301 AGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPG 360
AGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPG
Sbjct: 327 AGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPG 386
Query: 361 SGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIVLELLKE 420
SGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIVLELLKE
Sbjct: 387 SGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIVLELLKE 446
Query: 421 AMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLP 480
AMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLP
Sbjct: 447 AMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLP 506
Query: 481 VDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSIF 536
VDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSIF
Sbjct: 507 VDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSIF 562
>gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens]
Length = 536
Score = 1070 bits (2767), Expect = 0.0
Identities = 536/536 (100%), Positives = 536/536 (100%)
Query: 1 MCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPE 60
MCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPE
Sbjct: 1 MCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPLNGGQSRRSFLRNVMPE 60
Query: 61 NSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKG 120
NSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKG
Sbjct: 61 NSNFPYRRYDRLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKG 120
Query: 121 TQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKL 180
TQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKL
Sbjct: 121 TQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKL 180
Query: 181 MQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDD 240
MQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDD
Sbjct: 181 MQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDD 240
Query: 241 NVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAA 300
NVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAA
Sbjct: 241 NVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAA 300
Query: 301 AGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPG 360
AGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPG
Sbjct: 301 AGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPG 360
Query: 361 SGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIVLELLKE 420
SGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIVLELLKE
Sbjct: 361 SGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIVLELLKE 420
Query: 421 AMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLP 480
AMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLP
Sbjct: 421 AMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLP 480
Query: 481 VDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSIF 536
VDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSIF
Sbjct: 481 VDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSIF 536
>gi|4502011 adenylate kinase 1 [Homo sapiens]
Length = 194
Score = 236 bits (602), Expect = 4e-62
Identities = 112/191 (58%), Positives = 151/191 (79%)
Query: 345 EDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIME 404
E L+K KIIF++GGPGSGKGTQCEK+V+KYG+THLSTG+LLR E++S S R K + +IME
Sbjct: 3 EKLKKTKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRSEVSSGSARGKKLSEIME 62
Query: 405 RGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSA 464
+G LVP VL++L++AMVA + ++GFLIDGYPREV+QGEEF RRIG P L++ +D
Sbjct: 63 KGQLVPLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLLLYVDAGP 122
Query: 465 DTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDV 524
+TMT RLL+R +S VDD +TI KRLE YY+A+ PVIA+YE + + K+NAEG+ + V
Sbjct: 123 ETMTQRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSV 182
Query: 525 FLQLCTAIDSI 535
F Q+CT +D++
Sbjct: 183 FSQVCTHLDAL 193
Score = 135 bits (341), Expect = 7e-32
Identities = 65/187 (34%), Positives = 118/187 (63%), Gaps = 3/187 (1%)
Query: 105 RPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTG 164
+ KII V+GGPGSGKGTQ KI ++YG+ ++S G+LLR ++ S S+ K +++I+ G
Sbjct: 7 KTKIIFVVGGPGSGKGTQCEKIVQKYGYTHLSTGDLLRSEVSSGSARGK--KLSEIMEKG 64
Query: 165 ELAPQETTITEIKQKLM-QIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQR 223
+L P ET + ++ ++ ++ +G +IDG+PR+V Q FE +I P L++++ +
Sbjct: 65 QLVPLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIGQPTLLLYVDAGPET 124
Query: 224 LKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFY 283
+ +RLLKR E GR DDN + ++RL + + P++ +++++G++ +A+ D VF
Sbjct: 125 MTQRLLKRGETSGRVDDNEETIKKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFS 184
Query: 284 DISMAVD 290
+ +D
Sbjct: 185 QVCTHLD 191
>gi|7706497 UMP-CMP kinase 1 isoform a [Homo sapiens]
Length = 228
Score = 132 bits (333), Expect = 6e-31
Identities = 71/194 (36%), Positives = 117/194 (60%), Gaps = 7/194 (3%)
Query: 347 LRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELAS-ESERSKLIRDIMER 405
L K ++F++GGPG+GKGTQC ++VEKYG+THLS GELLR+E + +S+ +LI ++
Sbjct: 32 LMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKE 91
Query: 406 GDLVPSGIVLELLKEAM---VASLGDTRGFLIDGYPREVKQGEEFGRRI---GDPQLVIC 459
G +VP I + LLK M +A+ FLIDG+PR + + + + D V+
Sbjct: 92 GKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLF 151
Query: 460 MDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEG 519
DC+ + R L+R +SS DD +++ KR++ Y +++ P+I YE ++ KI+A
Sbjct: 152 FDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASK 211
Query: 520 TPEDVFLQLCTAID 533
+ ++VF ++ D
Sbjct: 212 SVDEVFDEVVQIFD 225
Score = 121 bits (304), Expect = 1e-27
Identities = 66/199 (33%), Positives = 110/199 (55%), Gaps = 8/199 (4%)
Query: 101 PTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKI 160
P +P ++ V+GGPG+GKGTQ +I E+YG+ ++S GELLR + + S + LI K
Sbjct: 30 PRLMKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDS-QYGELIEKY 88
Query: 161 ITTGELAPQETTITEIKQKLMQI----PDEEGIVIDGFPRDVAQALSFE---DQICTPDL 213
I G++ P E TI+ +K+++ Q + +IDGFPR+ + D
Sbjct: 89 IKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSF 148
Query: 214 VVFLACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFD 273
V+F C N+ ER L+R + GR DDN ++ ++R+ + Q+ P++ ++E G + D
Sbjct: 149 VLFFDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKID 208
Query: 274 ADRDEDEVFYDISMAVDNK 292
A + DEVF ++ D +
Sbjct: 209 ASKSVDEVFDEVVQIFDKE 227
>gi|53832001 adenylate kinase 3-like 1 isoform 7 [Homo sapiens]
Length = 223
Score = 87.0 bits (214), Expect = 4e-17
Identities = 57/195 (29%), Positives = 99/195 (50%), Gaps = 34/195 (17%)
Query: 355 IIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIV 414
I+G PGSGKGT C+++ + +G HLS+G LRE + + +E ++ + +E+ LVP ++
Sbjct: 10 ILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLLVPDHVI 69
Query: 415 LELLKEAMVASLGDTRG--FLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLL 472
L M++ L + RG +L+DG+PR + Q E +I + LVI ++ +T+ +RL
Sbjct: 70 TRL----MMSELENRRGQHWLLDGFPRTLGQAEALD-KICEVDLVISLNIPFETLKDRLS 124
Query: 473 QR-----------------------SRSSLPV----DDTTKTIAKRLEAYYRASIPVIAY 505
+R + P+ DD + +A RL Y + PVI
Sbjct: 125 RRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDVAKPVIEL 184
Query: 506 YETKTQLHKINAEGT 520
Y+++ LH+ + T
Sbjct: 185 YKSRGVLHQFSGTET 199
Score = 77.4 bits (189), Expect = 3e-14
Identities = 59/219 (26%), Positives = 107/219 (48%), Gaps = 34/219 (15%)
Query: 110 LVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQ 169
+++G PGSGKGT +IA+ +G Q++S G LR+ I +++ + +AK L
Sbjct: 9 VILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGE---MAKQYIEKSLLVP 65
Query: 170 ETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLL 229
+ IT + ++ + ++DGFPR + QA + D+IC DLV+ L + LK+RL
Sbjct: 66 DHVITRLMMSELENRRGQHWLLDGFPRTLGQAEAL-DKICEVDLVISLNIPFETLKDRLS 124
Query: 230 KR----------------------AEQQGRP-----DDNVKATQRRLMNFKQNAAPLVKY 262
+R + G P DD +A RL +K A P+++
Sbjct: 125 RRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDVAKPVIEL 184
Query: 263 FQEKGLIMTFDADRDEDEVFYDISMAVDNKLFP--NKEA 299
++ +G++ F + + ++++ + NK+ P +KEA
Sbjct: 185 YKSRGVLHQF-SGTETNKIWPYVYTLFSNKITPIQSKEA 222
>gi|53832003 adenylate kinase 3-like 1 isoform 5 [Homo sapiens]
Length = 223
Score = 87.0 bits (214), Expect = 4e-17
Identities = 57/195 (29%), Positives = 99/195 (50%), Gaps = 34/195 (17%)
Query: 355 IIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIV 414
I+G PGSGKGT C+++ + +G HLS+G LRE + + +E ++ + +E+ LVP ++
Sbjct: 10 ILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLLVPDHVI 69
Query: 415 LELLKEAMVASLGDTRG--FLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLL 472
L M++ L + RG +L+DG+PR + Q E +I + LVI ++ +T+ +RL
Sbjct: 70 TRL----MMSELENRRGQHWLLDGFPRTLGQAEALD-KICEVDLVISLNIPFETLKDRLS 124
Query: 473 QR-----------------------SRSSLPV----DDTTKTIAKRLEAYYRASIPVIAY 505
+R + P+ DD + +A RL Y + PVI
Sbjct: 125 RRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDVAKPVIEL 184
Query: 506 YETKTQLHKINAEGT 520
Y+++ LH+ + T
Sbjct: 185 YKSRGVLHQFSGTET 199
Score = 77.4 bits (189), Expect = 3e-14
Identities = 59/219 (26%), Positives = 107/219 (48%), Gaps = 34/219 (15%)
Query: 110 LVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQ 169
+++G PGSGKGT +IA+ +G Q++S G LR+ I +++ + +AK L
Sbjct: 9 VILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGE---MAKQYIEKSLLVP 65
Query: 170 ETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLL 229
+ IT + ++ + ++DGFPR + QA + D+IC DLV+ L + LK+RL
Sbjct: 66 DHVITRLMMSELENRRGQHWLLDGFPRTLGQAEAL-DKICEVDLVISLNIPFETLKDRLS 124
Query: 230 KR----------------------AEQQGRP-----DDNVKATQRRLMNFKQNAAPLVKY 262
+R + G P DD +A RL +K A P+++
Sbjct: 125 RRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDVAKPVIEL 184
Query: 263 FQEKGLIMTFDADRDEDEVFYDISMAVDNKLFP--NKEA 299
++ +G++ F + + ++++ + NK+ P +KEA
Sbjct: 185 YKSRGVLHQF-SGTETNKIWPYVYTLFSNKITPIQSKEA 222
>gi|8051579 adenylate kinase 3-like 1 isoform 6 [Homo sapiens]
Length = 223
Score = 87.0 bits (214), Expect = 4e-17
Identities = 57/195 (29%), Positives = 99/195 (50%), Gaps = 34/195 (17%)
Query: 355 IIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIV 414
I+G PGSGKGT C+++ + +G HLS+G LRE + + +E ++ + +E+ LVP ++
Sbjct: 10 ILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEKSLLVPDHVI 69
Query: 415 LELLKEAMVASLGDTRG--FLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLL 472
L M++ L + RG +L+DG+PR + Q E +I + LVI ++ +T+ +RL
Sbjct: 70 TRL----MMSELENRRGQHWLLDGFPRTLGQAEALD-KICEVDLVISLNIPFETLKDRLS 124
Query: 473 QR-----------------------SRSSLPV----DDTTKTIAKRLEAYYRASIPVIAY 505
+R + P+ DD + +A RL Y + PVI
Sbjct: 125 RRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDVAKPVIEL 184
Query: 506 YETKTQLHKINAEGT 520
Y+++ LH+ + T
Sbjct: 185 YKSRGVLHQFSGTET 199
Score = 77.4 bits (189), Expect = 3e-14
Identities = 59/219 (26%), Positives = 107/219 (48%), Gaps = 34/219 (15%)
Query: 110 LVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQ 169
+++G PGSGKGT +IA+ +G Q++S G LR+ I +++ + +AK L
Sbjct: 9 VILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGE---MAKQYIEKSLLVP 65
Query: 170 ETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLL 229
+ IT + ++ + ++DGFPR + QA + D+IC DLV+ L + LK+RL
Sbjct: 66 DHVITRLMMSELENRRGQHWLLDGFPRTLGQAEAL-DKICEVDLVISLNIPFETLKDRLS 124
Query: 230 KR----------------------AEQQGRP-----DDNVKATQRRLMNFKQNAAPLVKY 262
+R + G P DD +A RL +K A P+++
Sbjct: 125 RRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDVAKPVIEL 184
Query: 263 FQEKGLIMTFDADRDEDEVFYDISMAVDNKLFP--NKEA 299
++ +G++ F + + ++++ + NK+ P +KEA
Sbjct: 185 YKSRGVLHQF-SGTETNKIWPYVYTLFSNKITPIQSKEA 222
>gi|4502013 adenylate kinase 2 isoform a [Homo sapiens]
Length = 239
Score = 87.0 bits (214), Expect = 4e-17
Identities = 63/208 (30%), Positives = 98/208 (47%), Gaps = 32/208 (15%)
Query: 355 IIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIV 414
++G PG+GKGTQ +L E + HL+TG++LR +AS SE K ++ M+ G LV +V
Sbjct: 20 LLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMV 79
Query: 415 LELLKEAMVASLGDTRGFLIDGYPREVKQGEEFG----RRIGDPQLVICMDCSADTMTNR 470
+EL+++ + L GFL+DG+PR V+Q E +R VI + R
Sbjct: 80 VELIEKNLETPL-CKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRR 138
Query: 471 LLQR--------------SRSSLPV-------------DDTTKTIAKRLEAYYRASIPVI 503
+ R + P+ DD K + RL+AY+ + P+I
Sbjct: 139 ITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLI 198
Query: 504 AYYETKTQLHKINAEGTPEDVFLQLCTA 531
YY + I+A TP+ VF + A
Sbjct: 199 EYYRKRGIHSAIDASQTPDVVFASILAA 226
Score = 77.0 bits (188), Expect = 4e-14
Identities = 54/220 (24%), Positives = 99/220 (45%), Gaps = 33/220 (15%)
Query: 100 DPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAK 159
+P P+ +++G PG+GKGTQ+ ++AE + +++ G++LR + S S K +
Sbjct: 9 EPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGK--KLKA 66
Query: 160 IITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFED------------- 206
+ G+L E + I++ L + G ++DGFPR V QA +D
Sbjct: 67 TMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVI 126
Query: 207 QICTPDLVVFLACANQRLKERLLKRAEQQGRP------------------DDNVKATQRR 248
+ PD ++ + + + + ++ P DDN KA + R
Sbjct: 127 EFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIR 186
Query: 249 LMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMA 288
L + PL++Y++++G+ DA + D VF I A
Sbjct: 187 LQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAA 226
>gi|7524346 adenylate kinase 2 isoform b [Homo sapiens]
Length = 232
Score = 87.0 bits (214), Expect = 4e-17
Identities = 63/208 (30%), Positives = 98/208 (47%), Gaps = 32/208 (15%)
Query: 355 IIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIV 414
++G PG+GKGTQ +L E + HL+TG++LR +AS SE K ++ M+ G LV +V
Sbjct: 20 LLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGKKLKATMDAGKLVSDEMV 79
Query: 415 LELLKEAMVASLGDTRGFLIDGYPREVKQGEEFG----RRIGDPQLVICMDCSADTMTNR 470
+EL+++ + L GFL+DG+PR V+Q E +R VI + R
Sbjct: 80 VELIEKNLETPL-CKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRR 138
Query: 471 LLQR--------------SRSSLPV-------------DDTTKTIAKRLEAYYRASIPVI 503
+ R + P+ DD K + RL+AY+ + P+I
Sbjct: 139 ITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLI 198
Query: 504 AYYETKTQLHKINAEGTPEDVFLQLCTA 531
YY + I+A TP+ VF + A
Sbjct: 199 EYYRKRGIHSAIDASQTPDVVFASILAA 226
Score = 77.0 bits (188), Expect = 4e-14
Identities = 54/220 (24%), Positives = 99/220 (45%), Gaps = 33/220 (15%)
Query: 100 DPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAK 159
+P P+ +++G PG+GKGTQ+ ++AE + +++ G++LR + S S K +
Sbjct: 9 EPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSELGK--KLKA 66
Query: 160 IITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFED------------- 206
+ G+L E + I++ L + G ++DGFPR V QA +D
Sbjct: 67 TMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVI 126
Query: 207 QICTPDLVVFLACANQRLKERLLKRAEQQGRP------------------DDNVKATQRR 248
+ PD ++ + + + + ++ P DDN KA + R
Sbjct: 127 EFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIR 186
Query: 249 LMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMA 288
L + PL++Y++++G+ DA + D VF I A
Sbjct: 187 LQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAA 226
>gi|209915597 UMP-CMP kinase 1 isoform b [Homo sapiens]
Length = 179
Score = 77.4 bits (189), Expect = 3e-14
Identities = 48/190 (25%), Positives = 91/190 (47%), Gaps = 48/190 (25%)
Query: 347 LRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERG 406
L K ++F++GGPG+GKGTQC ++VE+ + + +A+ ++++K
Sbjct: 32 LMKPLVVFVLGGPGAGKGTQCARIVEE-----------MDQTMAANAQKNK--------- 71
Query: 407 DLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRI---GDPQLVICMDCS 463
FLIDG+PR + + + + D V+ DC+
Sbjct: 72 -------------------------FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCN 106
Query: 464 ADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPED 523
+ R L+R +SS DD +++ KR++ Y +++ P+I YE ++ KI+A + ++
Sbjct: 107 NEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDE 166
Query: 524 VFLQLCTAID 533
VF ++ D
Sbjct: 167 VFDEVVQIFD 176
Score = 75.5 bits (184), Expect = 1e-13
Identities = 48/195 (24%), Positives = 80/195 (41%), Gaps = 49/195 (25%)
Query: 101 PTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKI 160
P +P ++ V+GGPG+GKGTQ +I E
Sbjct: 30 PRLMKPLVVFVLGGPGAGKGTQCARIVE-------------------------------- 57
Query: 161 ITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFE---DQICTPDLVVFL 217
E+ Q + + +IDGFPR+ + D V+F
Sbjct: 58 --------------EMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFF 103
Query: 218 ACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRD 277
C N+ ER L+R + GR DDN ++ ++R+ + Q+ P++ ++E G + DA +
Sbjct: 104 DCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKS 163
Query: 278 EDEVFYDISMAVDNK 292
DEVF ++ D +
Sbjct: 164 VDEVFDEVVQIFDKE 178
>gi|19923437 adenylate kinase 3 [Homo sapiens]
Length = 227
Score = 69.7 bits (169), Expect = 6e-12
Identities = 51/193 (26%), Positives = 86/193 (44%), Gaps = 30/193 (15%)
Query: 355 IIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIV 414
I+G PGSGKGT ++ + HLS+G+LLR+ + +E L + +++G L+P ++
Sbjct: 12 IMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDVM 71
Query: 415 LELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQR 474
L + +L+DG+PR + Q E R VI ++ + + RL R
Sbjct: 72 TRLALHELKNL--TQYSWLLDGFPRTLPQAEALDRAY-QIDTVINLNVPFEVIKQRLTAR 128
Query: 475 ---------------SRSSLPVDDTT------------KTIAKRLEAYYRASIPVIAYYE 507
++ +DD T +T+ KRL+AY + PV+ YY+
Sbjct: 129 WIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQ 188
Query: 508 TKTQLHKINAEGT 520
K L + T
Sbjct: 189 KKGVLETFSGTET 201
Score = 62.0 bits (149), Expect = 1e-09
Identities = 50/191 (26%), Positives = 91/191 (47%), Gaps = 33/191 (17%)
Query: 110 LVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAK-IITTGELAP 168
+++G PGSGKGT S +I + +++S G+LLR + + ++AK I G+L P
Sbjct: 11 VIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNM---LRGTEIGVLAKAFIDQGKLIP 67
Query: 169 QETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERL 228
+ +T + ++ + ++DGFPR + QA + D+ D V+ L + +K+RL
Sbjct: 68 DDV-MTRLALHELKNLTQYSWLLDGFPRTLPQAEAL-DRAYQIDTVINLNVPFEVIKQRL 125
Query: 229 LKR----------------------AEQQGRP-----DDNVKATQRRLMNFKQNAAPLVK 261
R + G P DD + +RL ++ P+++
Sbjct: 126 TARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLE 185
Query: 262 YFQEKGLIMTF 272
Y+Q+KG++ TF
Sbjct: 186 YYQKKGVLETF 196
>gi|22749187 putative adenylate kinase-like protein C9orf98 [Homo
sapiens]
Length = 479
Score = 68.2 bits (165), Expect = 2e-11
Identities = 76/390 (19%), Positives = 157/390 (40%), Gaps = 81/390 (20%)
Query: 109 ILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAP 168
I+++G P SGK T ++ + + +++ L+ + T++ + ++ + P
Sbjct: 60 IVILGPPASGKTTIAMWLCKHLNSSLLTLENLILNEFSYTATEAR-----RLYLQRKTVP 114
Query: 169 QETTITEIKQKLMQIPD-EEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKER 227
+ I+++L + ++G ++DG P QAL + TP V+ L+ + L ER
Sbjct: 115 SALLVQLIQERLAEEDCIKQGWILDGIPETREQALRIQTLGITPRHVIVLSAPDTVLIER 174
Query: 228 LLKR-------------------AEQQGR---PDD-NVKATQRRLMNFKQNAAPLVKYFQ 264
L + +E Q R P+D + T ++L+ + +N ++ +
Sbjct: 175 NLGKRIDPQTGEIYHTTFDWPPESEIQNRLMVPEDISELETAQKLLEYHRNIVRVIPSYP 234
Query: 265 EKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDY 324
+ ++ AD+ +VFY V + N + P ++L
Sbjct: 235 K--ILKVISADQPCVDVFYQALTYVQSNHRTN-------APFTPRVLL------------ 273
Query: 325 EDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGEL 384
+G GSGK Q L +KY ++ G+L
Sbjct: 274 -------------------------------LGPVGSGKSLQAALLAQKYRLVNVCCGQL 302
Query: 385 LREELASESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQG 444
L+E +A + +LI+ E+ VP +++++L + + +G+++ G PR++ Q
Sbjct: 303 LKEAVADRTTFGELIQPFFEKEMAVPDSLLMKVLSQRLDQQDCIQKGWVLHGVPRDLDQA 362
Query: 445 EEFGRRIGDPQLVICMDCSADTMTNRLLQR 474
R +P V ++ D++ RL R
Sbjct: 363 HLLNRLGYNPNRVFFLNVPFDSIMERLTLR 392
Score = 50.1 bits (118), Expect = 5e-06
Identities = 55/217 (25%), Positives = 91/217 (41%), Gaps = 32/217 (14%)
Query: 101 PTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKI 160
P PR +L++G GSGK Q+ +A++Y + G+LL++ + ++ + LI
Sbjct: 266 PFTPR---VLLLGPVGSGKSLQAALLAQKYRLVNVCCGQLLKEAVADRTTFGE--LIQPF 320
Query: 161 ITTGELAPQETTITEIKQKL-MQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLAC 219
P + + Q+L Q ++G V+ G PRD+ QA P+ V FL
Sbjct: 321 FEKEMAVPDSLLMKVLSQRLDQQDCIQKGWVLHGVPRDLDQAHLLNRLGYNPNRVFFLNV 380
Query: 220 ANQRLKERLLKR-------------------AEQQGR----PDDNVKATQRRLMNFKQNA 256
+ ERL R E Q R P D + + ++ F +N+
Sbjct: 381 PFDSIMERLTLRRIDPVTGERYHLMYKPPPTMEIQARLLQNPKDAEEQVKLKMDLFYRNS 440
Query: 257 APLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKL 293
A L + + G +T + D+D VF I + N L
Sbjct: 441 ADLEQLY---GSAITLNGDQDPYTVFEYIESGIINPL 474
Score = 42.0 bits (97), Expect = 0.001
Identities = 54/210 (25%), Positives = 86/210 (40%), Gaps = 38/210 (18%)
Query: 353 IFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREEL---ASESERSKLIRDIMERGDLV 409
I I+G P SGK T L + + L+ L+ E A+E+ R L R V
Sbjct: 60 IVILGPPASGKTTIAMWLCKHLNSSLLTLENLILNEFSYTATEARRLYLQRKT------V 113
Query: 410 PSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQG------------------------- 444
PS ++++L++E + +G+++DG P +Q
Sbjct: 114 PSALLVQLIQERLAEEDCIKQGWILDGIPETREQALRIQTLGITPRHVIVLSAPDTVLIE 173
Query: 445 EEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIA 504
G+RI DPQ + D +Q +R +P D + A++L Y+R + VI
Sbjct: 174 RNLGKRI-DPQTGEIYHTTFDWPPESEIQ-NRLMVPEDISELETAQKLLEYHRNIVRVIP 231
Query: 505 YYETKTQLHKINAEGTPEDVFLQLCTAIDS 534
Y L I+A+ DVF Q T + S
Sbjct: 232 SY--PKILKVISADQPCVDVFYQALTYVQS 259
>gi|237858799 adenylate kinase domain containing 1 isoform 1 [Homo
sapiens]
Length = 1911
Score = 65.9 bits (159), Expect = 9e-11
Identities = 43/172 (25%), Positives = 87/172 (50%), Gaps = 8/172 (4%)
Query: 103 RPRPKI---ILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAK 159
+P+P + I+++G P SGK T + KI YG +++S+G LR +++ ++
Sbjct: 1405 KPKPTVPIRIIIVGPPKSGKTTVAKKITSEYGLKHLSIGGALRYVLNNHPETELALMLNW 1464
Query: 160 IITTGELAPQETTITEIKQKLMQ-IPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLA 218
+ G AP E I ++ LM+ + + G+VIDG+P Q E + P ++ L+
Sbjct: 1465 HLHKGMTAPDELAIQALELSLMESVCNTAGVVIDGYPVTKHQMNLLEARSIIPMVIFELS 1524
Query: 219 CANQRLKERLLKRAEQQGR----PDDNVKATQRRLMNFKQNAAPLVKYFQEK 266
++ + +RLL E + R ++ + + +++N + +Y+QE+
Sbjct: 1525 VPSKEIFKRLLLEKENEQRLPYPLHNSAQIVAVNNVKYRKNIGEIRQYYQEQ 1576
Score = 63.2 bits (152), Expect = 6e-10
Identities = 44/165 (26%), Positives = 79/165 (47%), Gaps = 6/165 (3%)
Query: 353 IFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELAS--ESERSKLIRDIMERGDLVP 410
I I+G P SGK T +K+ +YG HLS G LR L + E+E + ++ + +G P
Sbjct: 1414 IIIVGPPKSGKTTVAKKITSEYGLKHLSIGGALRYVLNNHPETELALMLNWHLHKGMTAP 1473
Query: 411 SGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNR 470
+ ++ L+ +++ S+ +T G +IDGYP Q R P ++ + + + R
Sbjct: 1474 DELAIQALELSLMESVCNTAGVVIDGYPVTKHQMNLLEARSIIPMVIFELSVPSKEIFKR 1533
Query: 471 LL----QRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQ 511
LL R P+ ++ + +A Y + + YY+ + Q
Sbjct: 1534 LLLEKENEQRLPYPLHNSAQIVAVNNVKYRKNIGEIRQYYQEQHQ 1578
Score = 42.4 bits (98), Expect = 0.001
Identities = 26/107 (24%), Positives = 54/107 (50%), Gaps = 3/107 (2%)
Query: 333 NVFGED-TMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELAS 391
++F ED T F+ C ++F G PG GK T + + + + +L E++A+
Sbjct: 14 DIFDEDETERNFLLSKPVCFVVF--GKPGVGKTTLARYITQAWKCIRVEALPILEEQIAA 71
Query: 392 ESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYP 438
E+E +++ ++ G +P +V++L+ E + + G++I P
Sbjct: 72 ETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIP 118
Score = 40.0 bits (92), Expect = 0.005
Identities = 70/304 (23%), Positives = 116/304 (38%), Gaps = 57/304 (18%)
Query: 100 DPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKI------------HS 147
+P + P I ++G GSGK ++AE+ +I E+L++K+
Sbjct: 985 EPLKAPPLRICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEE 1044
Query: 148 TSSNR---KWSLIAKIITTGELAPQETT--------ITE----IKQKLMQ---IPDE--- 186
S N K L I +E T +TE IK LM+ +P E
Sbjct: 1045 DSENEQAAKQELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILE 1104
Query: 187 --------------EGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRA 232
G ++DGFPR +A D+ PD VF+ +Q + +RLL
Sbjct: 1105 VILSEWWLKEPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQ 1164
Query: 233 EQQGRPDDNVKATQRRL---MNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAV 289
++ + K +++L M K + K E LI+ D R E+ V D ++
Sbjct: 1165 IEKWKLKQKKKLERKKLIKDMKAKIRVDTIAKRRAE--LILERDKKRRENVVRDDEEISE 1222
Query: 290 DNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRK 349
+ N + + L+ D E+ +G + E+Q D + + F D
Sbjct: 1223 EELEEDNDDI---ENILEDEFPKDEEEM--SGEEDEEQETDAIERLRGELGEKFEADTHN 1277
Query: 350 CKII 353
+II
Sbjct: 1278 LQII 1281
Score = 35.4 bits (80), Expect = 0.13
Identities = 39/208 (18%), Positives = 75/208 (36%), Gaps = 48/208 (23%)
Query: 353 IFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERS---------------- 396
I ++G GSGK +L EK H+ E+L+E+L ++E+
Sbjct: 994 ICLVGPQGSGKTMCGRQLAEKLNIFHIQFEEVLQEKLLLKTEKKVGPEFEEDSENEQAAK 1053
Query: 397 --------------------------------KLIRDIMERGDLVPSGIVLELLKEAMVA 424
++I+ + + +P I+ +L E +
Sbjct: 1054 QELEELAIQANVKVEEENTKKQLPEVQLTEEEEVIKSSLMENEPLPPEILEVILSEWWLK 1113
Query: 425 SLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDT 484
+ GF++DG+PR ++ + G R P + + + +RLL +
Sbjct: 1114 EPIRSTGFILDGFPRYPEEAQFLGDRGFFPDAAVFIQVDDQDIFDRLLPAQIEKWKLKQK 1173
Query: 485 TKTIAKRLEAYYRASIPVIAYYETKTQL 512
K K+L +A I V + + +L
Sbjct: 1174 KKLERKKLIKDMKAKIRVDTIAKRRAEL 1201
>gi|21450759 adenylate kinase domain containing 1 isoform 2 [Homo
sapiens]
Length = 421
Score = 42.4 bits (98), Expect = 0.001
Identities = 26/107 (24%), Positives = 54/107 (50%), Gaps = 3/107 (2%)
Query: 333 NVFGED-TMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELAS 391
++F ED T F+ C ++F G PG GK T + + + + +L E++A+
Sbjct: 14 DIFDEDETERNFLLSKPVCFVVF--GKPGVGKTTLARYITQAWKCIRVEALPILEEQIAA 71
Query: 392 ESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYP 438
E+E +++ ++ G +P +V++L+ E + + G++I P
Sbjct: 72 ETESGVMLQSMLISGQSIPDELVIKLMLEKLNSPEVCHFGYIITEIP 118
>gi|7706212 TAF9 RNA polymerase II, TATA box binding
protein-associated factor isoform b [Homo sapiens]
Length = 172
Score = 35.8 bits (81), Expect = 0.10
Identities = 16/36 (44%), Positives = 25/36 (69%)
Query: 109 ILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKK 144
IL+ G PG GK T ++A + G +YI+VG+L R++
Sbjct: 6 ILLTGTPGVGKTTLGKELASKSGLKYINVGDLAREE 41
Score = 33.1 bits (74), Expect = 0.66
Identities = 15/36 (41%), Positives = 22/36 (61%)
Query: 353 IFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREE 388
I + G PG GK T ++L K G +++ G+L REE
Sbjct: 6 ILLTGTPGVGKTTLGKELASKSGLKYINVGDLAREE 41
>gi|94721261 2',3'-cyclic nucleotide 3' phosphodiesterase [Homo
sapiens]
Length = 421
Score = 33.5 bits (75), Expect = 0.50
Identities = 18/39 (46%), Positives = 24/39 (61%), Gaps = 5/39 (12%)
Query: 337 EDTMGGFMEDLRKCKIIFIIGG-PGSGKGTQCEKLVEKY 374
EDT+ +E CK +FI+ G PGSGK T +V+KY
Sbjct: 40 EDTVATLLE----CKTLFILRGLPGSGKSTLARVIVDKY 74
>gi|148727333 adenylate kinase 7 [Homo sapiens]
Length = 723
Score = 33.1 bits (74), Expect = 0.66
Identities = 23/123 (18%), Positives = 49/123 (39%), Gaps = 29/123 (23%)
Query: 353 IFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELA------------------SESE 394
I I+G P GK + ++L Y H+ +++ E +A E E
Sbjct: 370 ICILGPPAVGKSSIAKELANYYKLHHIQLKDVISEAIAKLEAIVAPNDVGEGEEEVEEEE 429
Query: 395 RSKLIRDIMERGDLVPSGI-----------VLELLKEAMVASLGDTRGFLIDGYPREVKQ 443
+ + D E D + + ++ +KE + + +G+++DG+P+ Q
Sbjct: 430 EEENVEDAQELLDGIKESMEQNAGQLDDQYIIRFMKEKLKSMPCRNQGYILDGFPKTYDQ 489
Query: 444 GEE 446
++
Sbjct: 490 AKD 492
Score = 29.3 bits (64), Expect = 9.5
Identities = 20/77 (25%), Positives = 35/77 (45%), Gaps = 19/77 (24%)
Query: 176 IKQKLMQIP-DEEGIVIDGFPRDVAQALSF------------------EDQICTPDLVVF 216
+K+KL +P +G ++DGFP+ QA D++ P+ V
Sbjct: 464 MKEKLKSMPCRNQGYILDGFPKTYDQAKDLFNQEDEEEEDDVRGRMFPFDKLIIPEFVCA 523
Query: 217 LACANQRLKERLLKRAE 233
L +++ LKER++ E
Sbjct: 524 LDASDEFLKERVINLPE 540
>gi|62865612 TAF9 RNA polymerase II, TATA box binding
protein-associated factor isoform c [Homo sapiens]
Length = 169
Score = 32.7 bits (73), Expect = 0.86
Identities = 14/32 (43%), Positives = 22/32 (68%)
Query: 113 GGPGSGKGTQSLKIAERYGFQYISVGELLRKK 144
G PG GK T ++A + G +YI+VG+L R++
Sbjct: 7 GTPGVGKTTLGKELASKSGLKYINVGDLAREE 38
Score = 31.2 bits (69), Expect = 2.5
Identities = 14/32 (43%), Positives = 20/32 (62%)
Query: 357 GGPGSGKGTQCEKLVEKYGFTHLSTGELLREE 388
G PG GK T ++L K G +++ G+L REE
Sbjct: 7 GTPGVGKTTLGKELASKSGLKYINVGDLAREE 38
>gi|157388965 schlafen family member 11 [Homo sapiens]
Length = 901
Score = 32.3 bits (72), Expect = 1.1
Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Query: 285 ISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQ-GDDQLNVFGEDTMGGF 343
+ AV +P + AG+ ++ + ++ S DQ G + LN+ F
Sbjct: 526 LEAAVSPMDYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIF 585
Query: 344 MEDLRKCKIIFIIGGPGSGKGTQCEKLVEK 373
LRK + +F+ G PGSGK K++EK
Sbjct: 586 SRSLRKNRELFVHGLPGSGKTIMAMKIMEK 615
Score = 30.4 bits (67), Expect = 4.2
Identities = 13/36 (36%), Positives = 23/36 (63%)
Query: 94 EEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAER 129
++YE+F + + + + V G PGSGK ++KI E+
Sbjct: 580 QQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEK 615
>gi|157388963 schlafen family member 11 [Homo sapiens]
Length = 901
Score = 32.3 bits (72), Expect = 1.1
Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Query: 285 ISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQ-GDDQLNVFGEDTMGGF 343
+ AV +P + AG+ ++ + ++ S DQ G + LN+ F
Sbjct: 526 LEAAVSPMDYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIF 585
Query: 344 MEDLRKCKIIFIIGGPGSGKGTQCEKLVEK 373
LRK + +F+ G PGSGK K++EK
Sbjct: 586 SRSLRKNRELFVHGLPGSGKTIMAMKIMEK 615
Score = 30.4 bits (67), Expect = 4.2
Identities = 13/36 (36%), Positives = 23/36 (63%)
Query: 94 EEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAER 129
++YE+F + + + + V G PGSGK ++KI E+
Sbjct: 580 QQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEK 615
>gi|157388961 schlafen family member 11 [Homo sapiens]
Length = 901
Score = 32.3 bits (72), Expect = 1.1
Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Query: 285 ISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQ-GDDQLNVFGEDTMGGF 343
+ AV +P + AG+ ++ + ++ S DQ G + LN+ F
Sbjct: 526 LEAAVSPMDYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIF 585
Query: 344 MEDLRKCKIIFIIGGPGSGKGTQCEKLVEK 373
LRK + +F+ G PGSGK K++EK
Sbjct: 586 SRSLRKNRELFVHGLPGSGKTIMAMKIMEK 615
Score = 30.4 bits (67), Expect = 4.2
Identities = 13/36 (36%), Positives = 23/36 (63%)
Query: 94 EEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAER 129
++YE+F + + + + V G PGSGK ++KI E+
Sbjct: 580 QQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEK 615
>gi|157388959 schlafen family member 11 [Homo sapiens]
Length = 901
Score = 32.3 bits (72), Expect = 1.1
Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Query: 285 ISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQ-GDDQLNVFGEDTMGGF 343
+ AV +P + AG+ ++ + ++ S DQ G + LN+ F
Sbjct: 526 LEAAVSPMDYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIF 585
Query: 344 MEDLRKCKIIFIIGGPGSGKGTQCEKLVEK 373
LRK + +F+ G PGSGK K++EK
Sbjct: 586 SRSLRKNRELFVHGLPGSGKTIMAMKIMEK 615
Score = 30.4 bits (67), Expect = 4.2
Identities = 13/36 (36%), Positives = 23/36 (63%)
Query: 94 EEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAER 129
++YE+F + + + + V G PGSGK ++KI E+
Sbjct: 580 QQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEK 615
>gi|157388957 schlafen family member 11 [Homo sapiens]
Length = 901
Score = 32.3 bits (72), Expect = 1.1
Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Query: 285 ISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQ-GDDQLNVFGEDTMGGF 343
+ AV +P + AG+ ++ + ++ S DQ G + LN+ F
Sbjct: 526 LEAAVSPMDYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIF 585
Query: 344 MEDLRKCKIIFIIGGPGSGKGTQCEKLVEK 373
LRK + +F+ G PGSGK K++EK
Sbjct: 586 SRSLRKNRELFVHGLPGSGKTIMAMKIMEK 615
Score = 30.4 bits (67), Expect = 4.2
Identities = 13/36 (36%), Positives = 23/36 (63%)
Query: 94 EEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAER 129
++YE+F + + + + V G PGSGK ++KI E+
Sbjct: 580 QQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEK 615
>gi|56119108 schlafen family member 13 [Homo sapiens]
Length = 897
Score = 32.3 bits (72), Expect = 1.1
Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Query: 285 ISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQ-GDDQLNVFGEDTMGGF 343
+ AV +P + AG+ ++ + ++ S DQ G + LN+ F
Sbjct: 526 LEAAVSPMDYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIF 585
Query: 344 MEDLRKCKIIFIIGGPGSGKGTQCEKLVEK 373
LRK + +F+ G PGSGK K++EK
Sbjct: 586 SRSLRKNRELFVHGLPGSGKTIMAMKIMEK 615
Score = 30.4 bits (67), Expect = 4.2
Identities = 13/36 (36%), Positives = 23/36 (63%)
Query: 94 EEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAER 129
++YE+F + + + + V G PGSGK ++KI E+
Sbjct: 580 QQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEK 615
>gi|145580600 schlafen family member 5 [Homo sapiens]
Length = 891
Score = 31.2 bits (69), Expect = 2.5
Identities = 16/49 (32%), Positives = 27/49 (55%)
Query: 325 EDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEK 373
E+ G + LN+ ++LRK + +F+ G PGSGK +++EK
Sbjct: 546 EELGSEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGKTILALRIMEK 594
>gi|118572599 formin homology 2 domain containing 1 [Homo sapiens]
Length = 1164
Score = 30.8 bits (68), Expect = 3.3
Identities = 23/90 (25%), Positives = 37/90 (41%), Gaps = 18/90 (20%)
Query: 33 FVSQEKKTLPPLNGGQSRRSFLRNVMPENSNFPYRRYDRLPPIH----------QFSIES 82
F S+ K+ LP G+ RR+ + P+ SN LPP+H +F++
Sbjct: 671 FESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVHVIKAALLNFDEFAVSK 730
Query: 83 D--------TDLSETAELIEEYEVFDPTRP 104
D E + IEE ++ +P P
Sbjct: 731 DGIEKLLTMMPTEEERQKIEEAQLANPDIP 760
>gi|27501458 CTF18, chromosome transmission fidelity factor 18
homolog [Homo sapiens]
Length = 975
Score = 30.4 bits (67), Expect = 4.2
Identities = 15/39 (38%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 100 DPT-RPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISV 137
DP+ RP+ K+ L+ G PG GK T + IA G+ + +
Sbjct: 360 DPSQRPKQKVALLCGPPGLGKTTLAHVIARHAGYSVVEM 398
>gi|198442844 dynein, axonemal, heavy chain 10 [Homo sapiens]
Length = 4471
Score = 30.0 bits (66), Expect = 5.5
Identities = 13/35 (37%), Positives = 21/35 (60%), Gaps = 1/35 (2%)
Query: 98 VFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGF 132
+F+ + P I+ ++ PGS T +K+AER GF
Sbjct: 3868 IFEQSTPHSPIVFILS-PGSDPATDLMKLAERSGF 3901
>gi|169217198 PREDICTED: similar to hCG1644442 [Homo sapiens]
Length = 201
Score = 30.0 bits (66), Expect = 5.5
Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 10/56 (17%)
Query: 5 PEDPVEYLE---SCLQKVKELGGCDKVKWDTFV-------SQEKKTLPPLNGGQSR 50
PE PV ++E C +K K + G +K K+D QE K P+ GG+ +
Sbjct: 32 PEVPVNFVEFSKKCSEKRKTMSGKEKTKFDEMAKVDKVHYDQEMKDNGPVEGGKKK 87
>gi|169216377 PREDICTED: similar to hCG1644442 [Homo sapiens]
Length = 201
Score = 30.0 bits (66), Expect = 5.5
Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 10/56 (17%)
Query: 5 PEDPVEYLE---SCLQKVKELGGCDKVKWDTFV-------SQEKKTLPPLNGGQSR 50
PE PV ++E C +K K + G +K K+D QE K P+ GG+ +
Sbjct: 32 PEVPVNFVEFSKKCSEKRKTMSGKEKTKFDEMAKVDKVHYDQEMKDNGPVEGGKKK 87
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.136 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,252,538
Number of Sequences: 37866
Number of extensions: 984105
Number of successful extensions: 2678
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 2558
Number of HSP's gapped (non-prelim): 112
length of query: 536
length of database: 18,247,518
effective HSP length: 107
effective length of query: 429
effective length of database: 14,195,856
effective search space: 6090022224
effective search space used: 6090022224
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.