Search of human proteins with 27881423

Search of human proteins with 27881423

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27881423 purinergic receptor P2X2 isoform I [Homo sapiens]
         (399 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27881423 purinergic receptor P2X2 isoform I [Homo sapiens]         842   0.0  
gi|28416921 purinergic receptor P2X2 isoform H [Homo sapiens]         736   0.0  
gi|7706629 purinergic receptor P2X2 isoform C [Homo sapiens]          726   0.0  
gi|25092719 purinergic receptor P2X2 isoform A [Homo sapiens]         674   0.0  
gi|25092733 purinergic receptor P2X2 isoform D [Homo sapiens]         660   0.0  
gi|28416923 purinergic receptor P2X2 isoform B [Homo sapiens]         481   e-136
gi|28416927 purinergic receptor P2X4 [Homo sapiens]                   243   3e-64
gi|28416925 purinergic receptor P2X3 [Homo sapiens]                   228   7e-60
gi|4505545 purinergic receptor P2X1 [Homo sapiens]                    207   1e-53
gi|157419148 purinergic receptor P2X6 isoform 1 [Homo sapiens]        196   2e-50
gi|227116341 purinergic receptor P2X6 isoform 2 [Homo sapiens]        196   2e-50
gi|29294631 purinergic receptor P2X7 [Homo sapiens]                   194   2e-49
gi|28416933 purinergic receptor P2X5 isoform A [Homo sapiens]         194   2e-49
gi|28416935 purinergic receptor P2X5 isoform B [Homo sapiens]         187   1e-47
gi|150170670 piccolo isoform 2 [Homo sapiens]                          38   0.014
gi|150378539 piccolo isoform 1 [Homo sapiens]                          38   0.014
gi|54860079 nadrin isoform 1 [Homo sapiens]                            37   0.031
gi|54860105 nadrin isoform 2 [Homo sapiens]                            37   0.031
gi|28416937 purinergic receptor P2X5 isoform C [Homo sapiens]          37   0.031
gi|23397666 transcriptional co-repressor Sin3A [Homo sapiens]          37   0.041
gi|223941785 transcriptional co-repressor Sin3A [Homo sapiens]         37   0.041
gi|223941782 transcriptional co-repressor Sin3A [Homo sapiens]         37   0.041
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              36   0.054
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    36   0.070
gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]        36   0.070
gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]        36   0.070
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    35   0.092
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    35   0.092
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         35   0.092
gi|39812378 RAN binding protein 9 [Homo sapiens]                       35   0.16 

>gi|27881423 purinergic receptor P2X2 isoform I [Homo sapiens]
          Length = 399

 Score =  842 bits (2176), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRIHRAEKLPGERDGPRELHHHQGQ 60
           MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRIHRAEKLPGERDGPRELHHHQGQ
Sbjct: 1   MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRIHRAEKLPGERDGPRELHHHQGQ 60

Query: 61  GDHHVRAQSVGRGGVREAPRGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMA 120
           GDHHVRAQSVGRGGVREAPRGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMA
Sbjct: 61  GDHHVRAQSVGRGGVREAPRGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMA 120

Query: 121 PNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESF 180
           PNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESF
Sbjct: 121 PNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESF 180

Query: 181 TELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGT 240
           TELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGT
Sbjct: 181 TELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGT 240

Query: 241 TTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKV 300
           TTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKV
Sbjct: 241 TTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKV 300

Query: 301 YSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPA 360
           YSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPA
Sbjct: 301 YSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPA 360

Query: 361 FPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL 399
           FPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL
Sbjct: 361 FPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL 399


>gi|28416921 purinergic receptor P2X2 isoform H [Homo sapiens]
          Length = 379

 Score =  736 bits (1900), Expect = 0.0
 Identities = 361/400 (90%), Positives = 364/400 (91%), Gaps = 22/400 (5%)

Query: 1   MAAAQPKYPAGATARRLARGCWSALWDYETPKVIV-VRIHRAEKLPGERDGPRELHHHQG 59
           MAAAQPKYPAGATARRLARGCWSALWDYETPKVIV +R+H A  L               
Sbjct: 1   MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVSIRVHNATCLSD------------- 47

Query: 60  QGDHHVRAQSVGRGGVREAPRGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTM 119
                  A  V  G +     GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTM
Sbjct: 48  -------ADCVA-GELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTM 99

Query: 120 APNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGES 179
           APNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGES
Sbjct: 100 APNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGES 159

Query: 180 FTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKING 239
           FTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKING
Sbjct: 160 FTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKING 219

Query: 240 TTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNK 299
           TTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNK
Sbjct: 220 TTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNK 279

Query: 300 VYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGP 359
           VYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGP
Sbjct: 280 VYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGP 339

Query: 360 AFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL 399
           AFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL
Sbjct: 340 AFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL 379


>gi|7706629 purinergic receptor P2X2 isoform C [Homo sapiens]
          Length = 447

 Score =  726 bits (1874), Expect = 0.0
 Identities = 365/447 (81%), Positives = 372/447 (83%), Gaps = 48/447 (10%)

Query: 1   MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVR------IHRAEKL---------- 44
           MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVR      ++RA +L          
Sbjct: 1   MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60

Query: 45  -------PGERDGPREL-----------HHHQGQGDHHVRAQSVGR-------------- 72
                       GP               H     + +V+     R              
Sbjct: 61  FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPESIRVHNATCLSDADCVA 120

Query: 73  GGVREAPRGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIH 132
           G +     GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIH
Sbjct: 121 GELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIH 180

Query: 133 YPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGV 192
           YPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGV
Sbjct: 181 YPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGV 240

Query: 193 IINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIR 252
           IINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIR
Sbjct: 241 IINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIR 300

Query: 253 IDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKVCTP 312
           IDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKVCTP
Sbjct: 301 IDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKVCTP 360

Query: 313 SHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAP 372
           SHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAP
Sbjct: 361 SHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAP 420

Query: 373 SEQMVDTPASEPAQASTPTDPKGLAQL 399
           SEQMVDTPASEPAQASTPTDPKGLAQL
Sbjct: 421 SEQMVDTPASEPAQASTPTDPKGLAQL 447


>gi|25092719 purinergic receptor P2X2 isoform A [Homo sapiens]
          Length = 471

 Score =  674 bits (1739), Expect = 0.0
 Identities = 319/319 (100%), Positives = 319/319 (100%)

Query: 81  GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSK 140
           GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSK
Sbjct: 153 GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSK 212

Query: 141 GNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDL 200
           GNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDL
Sbjct: 213 GNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDL 272

Query: 201 DLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQ 260
           DLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQ
Sbjct: 273 DLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQ 332

Query: 261 AGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWP 320
           AGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWP
Sbjct: 333 AGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWP 392

Query: 321 VTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTP 380
           VTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTP
Sbjct: 393 VTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTP 452

Query: 381 ASEPAQASTPTDPKGLAQL 399
           ASEPAQASTPTDPKGLAQL
Sbjct: 453 ASEPAQASTPTDPKGLAQL 471



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 38/40 (95%), Positives = 38/40 (95%)

Query: 1  MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRIHR 40
          MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVR  R
Sbjct: 1  MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRR 40


>gi|25092733 purinergic receptor P2X2 isoform D [Homo sapiens]
          Length = 497

 Score =  660 bits (1702), Expect = 0.0
 Identities = 319/345 (92%), Positives = 319/345 (92%), Gaps = 26/345 (7%)

Query: 81  GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSK 140
           GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSK
Sbjct: 153 GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSK 212

Query: 141 GNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDL 200
           GNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDL
Sbjct: 213 GNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDL 272

Query: 201 DLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQ 260
           DLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQ
Sbjct: 273 DLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQ 332

Query: 261 AGKFSLIPTIINLATALTSVGV--------------------------GSFLCDWILLTF 294
           AGKFSLIPTIINLATALTSVGV                          GSFLCDWILLTF
Sbjct: 333 AGKFSLIPTIINLATALTSVGVVRNPLWGPSGCGGSTRPLHTGLCWPQGSFLCDWILLTF 392

Query: 295 MNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQG 354
           MNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQG
Sbjct: 393 MNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQG 452

Query: 355 AECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL 399
           AECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL
Sbjct: 453 AECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL 497



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 38/40 (95%), Positives = 38/40 (95%)

Query: 1  MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRIHR 40
          MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVR  R
Sbjct: 1  MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRR 40


>gi|28416923 purinergic receptor P2X2 isoform B [Homo sapiens]
          Length = 404

 Score =  481 bits (1239), Expect = e-136
 Identities = 232/248 (93%), Positives = 234/248 (94%), Gaps = 11/248 (4%)

Query: 81  GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSK 140
           GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSK
Sbjct: 153 GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSK 212

Query: 141 GNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDL 200
           GNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDL
Sbjct: 213 GNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDL 272

Query: 201 DLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQ 260
           DLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQ
Sbjct: 273 DLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQ 332

Query: 261 AGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKV----------- 309
           AGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDK+           
Sbjct: 333 AGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKMVDTPASEPAQA 392

Query: 310 CTPSHPSG 317
            TP+ P G
Sbjct: 393 STPTDPKG 400



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 38/40 (95%), Positives = 38/40 (95%)

Query: 1  MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRIHR 40
          MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVR  R
Sbjct: 1  MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRR 40



 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 24/26 (92%), Positives = 26/26 (100%)

Query: 374 EQMVDTPASEPAQASTPTDPKGLAQL 399
           ++MVDTPASEPAQASTPTDPKGLAQL
Sbjct: 379 DKMVDTPASEPAQASTPTDPKGLAQL 404


>gi|28416927 purinergic receptor P2X4 [Homo sapiens]
          Length = 388

 Score =  243 bits (619), Expect = 3e-64
 Identities = 128/235 (54%), Positives = 161/235 (68%), Gaps = 8/235 (3%)

Query: 81  GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQ--FLGTMAPNFTILIKNSIHYPKFHF 138
           G+ TGRCV +  G  KTCEV  WCPVED   V Q  FL   A NFT+L+KN+I YPKF+F
Sbjct: 143 GVSTGRCVAF-NGSVKTCEVAAWCPVEDDTHVPQPAFLKA-AENFTLLVKNNIWYPKFNF 200

Query: 139 SKGNIADR-TDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWD 197
           SK NI    T  YLK C +   +D +CPIF+LG IVE AG SF ++A +GG++G+ +NWD
Sbjct: 201 SKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENAGHSFQDMAVEGGIMGIQVNWD 260

Query: 198 CDLDLPASECNPKYSFRRLDPKHVP--ASSGYNFRFAKYYK-INGTTTRTLIKAYGIRID 254
           C+LD  AS C P+YSFRRLD + V    S GYNFRFAKYY+ + G   RTLIKAYGIR D
Sbjct: 261 CNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKYYRDLAGNEQRTLIKAYGIRFD 320

Query: 255 VIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKV 309
           +IV G+AGKF +IPT+IN+ + L  +G+ + LCD I+L  M K   Y  KK+  V
Sbjct: 321 IIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLYCMKKRLYYREKKYKYV 375


>gi|28416925 purinergic receptor P2X3 [Homo sapiens]
          Length = 397

 Score =  228 bits (581), Expect = 7e-60
 Identities = 121/233 (51%), Positives = 154/233 (66%), Gaps = 6/233 (2%)

Query: 81  GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSK 140
           G+ TGRCV Y     +TCE+ GWCP E   +V   +   A NFTI IKNSI +P F+F K
Sbjct: 131 GILTGRCVNY-SSVLRTCEIQGWCPTEVD-TVETPIMMEAENFTIFIKNSIRFPLFNFEK 188

Query: 141 GNIADR-TDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCD 199
           GN+    T   +K C FH   D +CPI ++G +V+ AG+ F +LA  GGV+G+ I W CD
Sbjct: 189 GNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLARTGGVLGIKIGWVCD 248

Query: 200 LDLPASECNPKYSFRRLDP--KHVPASSGYNFRFAKYYKI-NGTTTRTLIKAYGIRIDVI 256
           LD    +C PKYSF RLD   +    S GYNFRFAKYYK+ NG+  RTL+KA+GIR DV+
Sbjct: 249 LDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKAFGIRFDVL 308

Query: 257 VHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKV 309
           V+G AGKF++IPTII+   A TSVGVG+ LCD ILL F+     Y  KKF++V
Sbjct: 309 VYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKAKKFEEV 361


>gi|4505545 purinergic receptor P2X1 [Homo sapiens]
          Length = 399

 Score =  207 bits (527), Expect = 1e-53
 Identities = 100/237 (42%), Positives = 151/237 (63%), Gaps = 6/237 (2%)

Query: 73  GGVREAPRGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQ-FLGTMAPNFTILIKNSI 131
           G  +   +G+RTG+CV +     KTCE+FGWCPVE    + +  L   A NFT+ IKNSI
Sbjct: 135 GKAKRKAQGIRTGKCVAF-NDTVKTCEIFGWCPVEVDDDIPRPALLREAENFTLFIKNSI 193

Query: 132 HYPKFHFSKGNIADRTDG-YLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVI 190
            +P+F  ++ N+ +  +  ++K C FH+     CP+F+LG++V+++G++F+ LA KGGV+
Sbjct: 194 SFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQESGQNFSTLAEKGGVV 253

Query: 191 GVIINWDCDLDLPASECNPKYSFRRL-DPKHVPASSGYNFRFAKYYKINGTTTRTLIKAY 249
           G+ I+W CDLD     C P Y F  L + K++  S G+NFRFA+++  NGT  R L K +
Sbjct: 254 GITIDWHCDLDWHVRHCRPIYEFHGLYEEKNL--SPGFNFRFARHFVENGTNYRHLFKVF 311

Query: 250 GIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKF 306
           GIR D++V G+AGKF +IPT+  + + +   GV + LCD +LL  + K   Y  KKF
Sbjct: 312 GIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKRHYYKQKKF 368


>gi|157419148 purinergic receptor P2X6 isoform 1 [Homo sapiens]
          Length = 441

 Score =  196 bits (499), Expect = 2e-50
 Identities = 117/302 (38%), Positives = 161/302 (53%), Gaps = 20/302 (6%)

Query: 71  GRGGVREAPRGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNS 130
           G GG      G++TG+CV  + G  +TCE++ WCPVE G   S+ L   A NFT+ IKN+
Sbjct: 147 GEGGTHS--HGVKTGQCV-VFNGTHRTCEIWSWCPVESGVVPSRPLLAQAQNFTLFIKNT 203

Query: 131 IHYPKFHFSKGNIADRTDG-YLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGV 189
           + + KF+FSK N  +  D  Y K C +      YCP+F++G +V KAG +F +LA  GG 
Sbjct: 204 VTFSKFNFSKSNALETWDPTYFKHCRYEPQFSPYCPVFRIGDLVAKAGGTFEDLALLGGS 263

Query: 190 IGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFA-KYYKINGTTTRTLIKA 248
           +G+ ++WDCDLD   S C P YSF+  +         YNFR A  +++  G   RTL+K 
Sbjct: 264 VGIRVHWDCDLDTGDSGCWPHYSFQLQE-------KSYNFRTATHWWEQPGVEARTLLKL 316

Query: 249 YGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDK 308
           YGIR D++V GQAGKF LIPT + L T    +GV +F CD +LL    +   Y   K+++
Sbjct: 317 YGIRFDILVTGQAGKFGLIPTAVTLGTGAAWLGVVTFFCDLLLLYVDREAHFYWRTKYEE 376

Query: 309 VCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCP 368
              P   + S    LA        E   RS    P+P +   G Q         P  PCP
Sbjct: 377 AKAPKATANSVWRELALASQARLAECLRRS--SAPAPTATAAGSQ------TQTPGWPCP 428

Query: 369 IS 370
            S
Sbjct: 429 SS 430


>gi|227116341 purinergic receptor P2X6 isoform 2 [Homo sapiens]
          Length = 415

 Score =  196 bits (499), Expect = 2e-50
 Identities = 117/302 (38%), Positives = 161/302 (53%), Gaps = 20/302 (6%)

Query: 71  GRGGVREAPRGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNS 130
           G GG      G++TG+CV  + G  +TCE++ WCPVE G   S+ L   A NFT+ IKN+
Sbjct: 121 GEGGTHS--HGVKTGQCV-VFNGTHRTCEIWSWCPVESGVVPSRPLLAQAQNFTLFIKNT 177

Query: 131 IHYPKFHFSKGNIADRTDG-YLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGV 189
           + + KF+FSK N  +  D  Y K C +      YCP+F++G +V KAG +F +LA  GG 
Sbjct: 178 VTFSKFNFSKSNALETWDPTYFKHCRYEPQFSPYCPVFRIGDLVAKAGGTFEDLALLGGS 237

Query: 190 IGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFA-KYYKINGTTTRTLIKA 248
           +G+ ++WDCDLD   S C P YSF+  +         YNFR A  +++  G   RTL+K 
Sbjct: 238 VGIRVHWDCDLDTGDSGCWPHYSFQLQE-------KSYNFRTATHWWEQPGVEARTLLKL 290

Query: 249 YGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDK 308
           YGIR D++V GQAGKF LIPT + L T    +GV +F CD +LL    +   Y   K+++
Sbjct: 291 YGIRFDILVTGQAGKFGLIPTAVTLGTGAAWLGVVTFFCDLLLLYVDREAHFYWRTKYEE 350

Query: 309 VCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCP 368
              P   + S    LA        E   RS    P+P +   G Q         P  PCP
Sbjct: 351 AKAPKATANSVWRELALASQARLAECLRRS--SAPAPTATAAGSQ------TQTPGWPCP 402

Query: 369 IS 370
            S
Sbjct: 403 SS 404


>gi|29294631 purinergic receptor P2X7 [Homo sapiens]
          Length = 595

 Score =  194 bits (492), Expect = 2e-49
 Identities = 103/245 (42%), Positives = 150/245 (61%), Gaps = 9/245 (3%)

Query: 72  RGGVREAPRGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQ-FLGTMAPNFTILIKNS 130
           +G +    +G++TGRCV  Y+G  KTCEV  WCP+E      +  L   A NFT+LIKN+
Sbjct: 137 KGWMDPQSKGIQTGRCV-VYEGNQKTCEVSAWCPIEAVEEAPRPALLNSAENFTVLIKNN 195

Query: 131 IHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVI 190
           I +P  +++  NI     G    CTFH+  +  CPIF+LG I  + G++F+++A +GG++
Sbjct: 196 IDFPGHNYTTRNILP---GLNITCTFHKTQNPQCPIFRLGDIFRETGDNFSDVAIQGGIM 252

Query: 191 GVIINWDCDLDLPASECNPKYSFRRLDPK--HVPASSGYNFRFAKYYKINGTTTRTLIKA 248
           G+ I WDC+LD     C PKYSFRRLD K  +V    GYNFR+AKYYK N    RTLIK 
Sbjct: 253 GIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYYKENNVEKRTLIKV 312

Query: 249 YGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSH-KKFD 307
           +GIR D++V G  GKF +I  ++ + + L+  G+ +   D+++ T+ + N   SH   + 
Sbjct: 313 FGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTY-SSNCCRSHIYPWC 371

Query: 308 KVCTP 312
           K C P
Sbjct: 372 KCCQP 376


>gi|28416933 purinergic receptor P2X5 isoform A [Homo sapiens]
          Length = 422

 Score =  194 bits (492), Expect = 2e-49
 Identities = 115/301 (38%), Positives = 159/301 (52%), Gaps = 36/301 (11%)

Query: 78  APRGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFH 137
           A  G++TGRC+        TCE+F WCP+E  +   +     A +FTI IKN I +PKF+
Sbjct: 143 AGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAEDFTIFIKNHIRFPKFN 202

Query: 138 FSKGNIADRTD-GYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINW 196
           FSK N+ D  D  +LK C F   +  YCPIF+LG ++  AG  F ++A +GGVIG+ I W
Sbjct: 203 FSKSNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDFQDIALEGGVIGINIEW 261

Query: 197 DCDLDLPASECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK-INGTTTRTLIKAYGIRID 254
           +CDLD  ASEC+P YSF RLD K     SSGYNFRFA+YY+   G   RTL+KAYGIR D
Sbjct: 262 NCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAAGVEFRTLMKAYGIRFD 321

Query: 255 VIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKV----- 309
           V+V+G+                      G+F CD +L+  + K + Y  KK+++V     
Sbjct: 322 VMVNGK----------------------GAFFCDLVLIYLIKKREFYRDKKYEEVRGLED 359

Query: 310 CTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQ-----QGAECGPAFPPL 364
            +      +  + L+  L   P   G   + +   PP  + G       G+ C     P 
Sbjct: 360 SSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPH 419

Query: 365 R 365
           R
Sbjct: 420 R 420


>gi|28416935 purinergic receptor P2X5 isoform B [Homo sapiens]
          Length = 397

 Score =  187 bits (475), Expect = 1e-47
 Identities = 111/300 (37%), Positives = 156/300 (52%), Gaps = 35/300 (11%)

Query: 78  APRGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFH 137
           A  G++TGRC+        TCE+F WCP+E  +   +     A +FTI IKN I +PKF+
Sbjct: 119 AGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAEDFTIFIKNHIRFPKFN 178

Query: 138 FSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWD 197
           FS   +  +   +LK C F   +  YCPIF+LG ++  AG  F ++A +GGVIG+ I W+
Sbjct: 179 FSNNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDFQDIALEGGVIGINIEWN 237

Query: 198 CDLDLPASECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK-INGTTTRTLIKAYGIRIDV 255
           CDLD  ASEC+P YSF RLD K     SSGYNFRFA+YY+   G   RTL+KAYGIR DV
Sbjct: 238 CDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAAGVEFRTLMKAYGIRFDV 297

Query: 256 IVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKV-----C 310
           +V+G+                      G+F CD +L+  + K + Y  KK+++V      
Sbjct: 298 MVNGK----------------------GAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS 335

Query: 311 TPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQ-----QGAECGPAFPPLR 365
           +      +  + L+  L   P   G   + +   PP  + G       G+ C     P R
Sbjct: 336 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR 395


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 38.1 bits (87), Expect = 0.014
 Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 18/90 (20%)

Query: 312 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 371
           PS PS S P           P PG         PP+ Q G + ++ GPA PP +P  ++ 
Sbjct: 296 PSLPSPSKPPI-------QQPTPG--------KPPAQQPGHEKSQPGPAKPPAQPSGLTK 340

Query: 372 PSEQM---VDTPASEPAQASTPTDPKGLAQ 398
           P  Q    V  P   P     P  P G A+
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAK 370



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 30/103 (29%), Positives = 36/103 (34%), Gaps = 27/103 (26%)

Query: 312 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 371
           P+ PSG     L + L Q P         + P  P G         GPA PP +      
Sbjct: 332 PAQPSG-----LTKPLAQQP------GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380

Query: 372 PSEQMVD------------TPASEPAQASTPTD----PKGLAQ 398
           PS +               TPA +P  A  PT     PK LAQ
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 5/72 (6%)

Query: 328 GQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFP-PLRPCPISAPSEQMVDTPASEPAQ 386
           G A P P      + PS   G       + GPA P P +P     PS+Q    P S    
Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ----PGSAKPS 540

Query: 387 ASTPTDPKGLAQ 398
           A  P+  K  AQ
Sbjct: 541 AQQPSPAKPSAQ 552


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 38.1 bits (87), Expect = 0.014
 Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 18/90 (20%)

Query: 312 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 371
           PS PS S P           P PG         PP+ Q G + ++ GPA PP +P  ++ 
Sbjct: 296 PSLPSPSKPPI-------QQPTPG--------KPPAQQPGHEKSQPGPAKPPAQPSGLTK 340

Query: 372 PSEQM---VDTPASEPAQASTPTDPKGLAQ 398
           P  Q    V  P   P     P  P G A+
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAK 370



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 30/103 (29%), Positives = 36/103 (34%), Gaps = 27/103 (26%)

Query: 312 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 371
           P+ PSG     L + L Q P         + P  P G         GPA PP +      
Sbjct: 332 PAQPSG-----LTKPLAQQP------GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380

Query: 372 PSEQMVD------------TPASEPAQASTPTD----PKGLAQ 398
           PS +               TPA +P  A  PT     PK LAQ
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 5/72 (6%)

Query: 328 GQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFP-PLRPCPISAPSEQMVDTPASEPAQ 386
           G A P P      + PS   G       + GPA P P +P     PS+Q    P S    
Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ----PGSAKPS 540

Query: 387 ASTPTDPKGLAQ 398
           A  P+  K  AQ
Sbjct: 541 AQQPSPAKPSAQ 552


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 37.0 bits (84), Expect = 0.031
 Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 7/86 (8%)

Query: 312 PSHPSGSWPVTLARVLGQ---APPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCP 368
           P + +G  P TL R + +   APP+PG    +  P  P GQ     ++  P+  P  P  
Sbjct: 618 PHNAAGPSPHTLRRAVKKPAPAPPKPG----NPPPGHPGGQSSSGTSQHPPSLSPKPPTR 673

Query: 369 ISAPSEQMVDTPASEPAQASTPTDPK 394
             +P  Q    P  +P+  S  + P+
Sbjct: 674 SPSPPTQHTGQPPGQPSAPSQLSAPR 699



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 25/87 (28%), Positives = 31/87 (35%), Gaps = 15/87 (17%)

Query: 312 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 371
           P HP G      +    Q PP    +   + PSPP+   GQ      P   P  P  +SA
Sbjct: 648 PGHPGGQ----SSSGTSQHPPSLSPKPPTRSPSPPTQHTGQ------PPGQPSAPSQLSA 697

Query: 372 P-----SEQMVDTPASEPAQASTPTDP 393
           P     S   +  P   P Q  T   P
Sbjct: 698 PRRYSSSLSPIQAPNHPPPQPPTQATP 724


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 37.0 bits (84), Expect = 0.031
 Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 7/86 (8%)

Query: 312 PSHPSGSWPVTLARVLGQ---APPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCP 368
           P + +G  P TL R + +   APP+PG    +  P  P GQ     ++  P+  P  P  
Sbjct: 540 PHNAAGPSPHTLRRAVKKPAPAPPKPG----NPPPGHPGGQSSSGTSQHPPSLSPKPPTR 595

Query: 369 ISAPSEQMVDTPASEPAQASTPTDPK 394
             +P  Q    P  +P+  S  + P+
Sbjct: 596 SPSPPTQHTGQPPGQPSAPSQLSAPR 621



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 25/87 (28%), Positives = 31/87 (35%), Gaps = 15/87 (17%)

Query: 312 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 371
           P HP G      +    Q PP    +   + PSPP+   GQ      P   P  P  +SA
Sbjct: 570 PGHPGGQ----SSSGTSQHPPSLSPKPPTRSPSPPTQHTGQ------PPGQPSAPSQLSA 619

Query: 372 P-----SEQMVDTPASEPAQASTPTDP 393
           P     S   +  P   P Q  T   P
Sbjct: 620 PRRYSSSLSPIQAPNHPPPQPPTQATP 646


>gi|28416937 purinergic receptor P2X5 isoform C [Homo sapiens]
          Length = 178

 Score = 37.0 bits (84), Expect = 0.031
 Identities = 14/30 (46%), Positives = 19/30 (63%)

Query: 78  APRGLRTGRCVPYYQGPSKTCEVFGWCPVE 107
           A  G++TGRC+        TCE+F WCP+E
Sbjct: 143 AGNGVKTGRCLRRENLARGTCEIFAWCPLE 172


>gi|23397666 transcriptional co-repressor Sin3A [Homo sapiens]
          Length = 1273

 Score = 36.6 bits (83), Expect = 0.041
 Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 3/58 (5%)

Query: 333 EPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTP 390
           +P  +   QHPS PS Q     A+  P  PP +   +S PS+    TPAS+      P
Sbjct: 217 QPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAK---VSKPSQLQAHTPASQQTPPLPP 271


>gi|223941785 transcriptional co-repressor Sin3A [Homo sapiens]
          Length = 1273

 Score = 36.6 bits (83), Expect = 0.041
 Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 3/58 (5%)

Query: 333 EPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTP 390
           +P  +   QHPS PS Q     A+  P  PP +   +S PS+    TPAS+      P
Sbjct: 217 QPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAK---VSKPSQLQAHTPASQQTPPLPP 271


>gi|223941782 transcriptional co-repressor Sin3A [Homo sapiens]
          Length = 1273

 Score = 36.6 bits (83), Expect = 0.041
 Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 3/58 (5%)

Query: 333 EPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTP 390
           +P  +   QHPS PS Q     A+  P  PP +   +S PS+    TPAS+      P
Sbjct: 217 QPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAK---VSKPSQLQAHTPASQQTPPLPP 271


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 36.2 bits (82), Expect = 0.054
 Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 11/78 (14%)

Query: 331 PPEPGHRSEDQHPSPPS--GQEGQQGAECGPA-----FPPLRPCPISAP---SEQMVDTP 380
           PP+P  + + Q P PP+  G EG   A C P       P L P     P    E+ +   
Sbjct: 522 PPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPS 581

Query: 381 ASEPAQASTPT-DPKGLA 397
           +   +Q+ TPT  PKGLA
Sbjct: 582 SGYSSQSGTPTLPPKGLA 599


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 35.8 bits (81), Expect = 0.070
 Identities = 27/86 (31%), Positives = 36/86 (41%), Gaps = 5/86 (5%)

Query: 309 VCTPSHPSGSWPVT-LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPC 367
           V  P  P  S PV+  A    QAPP          PSPP+       A   P  PP    
Sbjct: 673 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP---- 728

Query: 368 PISAPSEQMVDTPASEPAQASTPTDP 393
           P++AP  Q+  +P + P  + + T P
Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPP 754



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 27/88 (30%), Positives = 31/88 (35%), Gaps = 3/88 (3%)

Query: 312 PSHPSGSWPVT-LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPC-PI 369
           P  P  S P++  A    QAPP          PSPP+       A   P  PPL    P+
Sbjct: 707 PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL 766

Query: 370 SAPSEQMVDTPASEPAQASTPTDPKGLA 397
             P       P S P     P  P  LA
Sbjct: 767 QVPPSPPASLPMS-PLAKPPPQAPPALA 793


>gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]
          Length = 1337

 Score = 35.8 bits (81), Expect = 0.070
 Identities = 23/79 (29%), Positives = 29/79 (36%), Gaps = 19/79 (24%)

Query: 312 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 371
           P  PS   P+    +    PP P H+     P PP          C P  PP  PCP + 
Sbjct: 84  PMPPSAQGPLPPCPI---RPPFPNHQMRHPFPVPP----------CFPPMPPPMPCPNNP 130

Query: 372 PSEQMVDTPASEPAQASTP 390
           P       P + P Q + P
Sbjct: 131 P------VPGAPPGQGTFP 143


>gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]
          Length = 1374

 Score = 35.8 bits (81), Expect = 0.070
 Identities = 23/79 (29%), Positives = 29/79 (36%), Gaps = 19/79 (24%)

Query: 312 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 371
           P  PS   P+    +    PP P H+     P PP          C P  PP  PCP + 
Sbjct: 84  PMPPSAQGPLPPCPI---RPPFPNHQMRHPFPVPP----------CFPPMPPPMPCPNNP 130

Query: 372 PSEQMVDTPASEPAQASTP 390
           P       P + P Q + P
Sbjct: 131 P------VPGAPPGQGTFP 143


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 35.4 bits (80), Expect = 0.092
 Identities = 27/83 (32%), Positives = 33/83 (39%), Gaps = 5/83 (6%)

Query: 309 VCTPSHPSGSWPVT-LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPC 367
           V  P  P  S PV+  A    QAPP          PSPP+       A   P  PP    
Sbjct: 448 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP---- 503

Query: 368 PISAPSEQMVDTPASEPAQASTP 390
           P++AP  Q+   P   P   +TP
Sbjct: 504 PLAAPPLQLAKPPPQAPPALATP 526


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 35.4 bits (80), Expect = 0.092
 Identities = 27/83 (32%), Positives = 33/83 (39%), Gaps = 5/83 (6%)

Query: 309 VCTPSHPSGSWPVT-LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPC 367
           V  P  P  S PV+  A    QAPP          PSPP+       A   P  PP    
Sbjct: 409 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP---- 464

Query: 368 PISAPSEQMVDTPASEPAQASTP 390
           P++AP  Q+   P   P   +TP
Sbjct: 465 PLAAPPLQLAKPPPQAPPALATP 487



 Score = 30.0 bits (66), Expect = 3.8
 Identities = 21/81 (25%), Positives = 33/81 (40%), Gaps = 2/81 (2%)

Query: 313 SHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAP 372
           S P+ S P   AR   +AP  P         +    Q      +  PA  PL   P++ P
Sbjct: 241 SSPARSGPS--ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 298

Query: 373 SEQMVDTPASEPAQASTPTDP 393
           S     +P++ P+  + P+ P
Sbjct: 299 SPSAPPSPSAPPSLQTLPSPP 319


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 35.4 bits (80), Expect = 0.092
 Identities = 23/83 (27%), Positives = 31/83 (37%)

Query: 315  PSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSE 374
            PS + P+    VL  +P      +  Q P P        G     A P   P P+ APS 
Sbjct: 1600 PSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSS 1659

Query: 375  QMVDTPASEPAQASTPTDPKGLA 397
                 PA  P+   +P   + LA
Sbjct: 1660 TQTMLPAPVPSPLPSPASTQTLA 1682


>gi|39812378 RAN binding protein 9 [Homo sapiens]
          Length = 729

 Score = 34.7 bits (78), Expect = 0.16
 Identities = 31/86 (36%), Positives = 34/86 (39%), Gaps = 8/86 (9%)

Query: 320 PVTLARVLGQAPPEPGHRSEDQHPS-PPSGQEGQQGAECGPA----FPPLRPCPISA--- 371
           P  LA V G   P P   S    P+  P G  G +G     A     PP  P P +A   
Sbjct: 24  PAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPP 83

Query: 372 PSEQMVDTPASEPAQASTPTDPKGLA 397
           P       PAS  A AS P  P GLA
Sbjct: 84  PPPPPPPPPASAAAPASGPPAPPGLA 109


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,286,640
Number of Sequences: 37866
Number of extensions: 990587
Number of successful extensions: 5363
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 183
Number of HSP's that attempted gapping in prelim test: 4901
Number of HSP's gapped (non-prelim): 596
length of query: 399
length of database: 18,247,518
effective HSP length: 104
effective length of query: 295
effective length of database: 14,309,454
effective search space: 4221288930
effective search space used: 4221288930
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.