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Search of human proteins with 27659734
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27659734 eukaryotic translation initiation factor 4E family
member 3 isoform b [Homo sapiens]
(118 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|197382708 eukaryotic translation initiation factor 4E family ... 245 5e-66
gi|197382664 eukaryotic translation initiation factor 4E family ... 245 5e-66
gi|197382649 eukaryotic translation initiation factor 4E family ... 245 5e-66
gi|27659734 eukaryotic translation initiation factor 4E family m... 245 5e-66
gi|4757702 eukaryotic translation initiation factor 4E member 2 ... 69 6e-13
gi|194578907 eukaryotic translation initiation factor 4E isoform... 54 2e-08
gi|4503535 eukaryotic translation initiation factor 4E isoform 1... 54 2e-08
gi|169211405 PREDICTED: similar to hCG1777996 [Homo sapiens] 54 2e-08
gi|169211874 PREDICTED: similar to hCG1777996 [Homo sapiens] 54 2e-08
gi|169210992 PREDICTED: hypothetical protein LOC100131693 [Homo ... 54 2e-08
gi|150378456 eukaryotic translation initiation factor 4E family ... 49 8e-07
gi|194578909 eukaryotic translation initiation factor 4E isoform... 40 4e-04
gi|154350241 brefeldin A-inhibited guanine nucleotide-exchange p... 27 2.6
gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo ... 27 2.6
gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo s... 27 2.6
gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo ... 27 2.6
gi|31377705 centrosomal protein 97kDa [Homo sapiens] 27 4.5
gi|32483361 apoptotic peptidase activating factor 1 isoform d [H... 26 7.7
gi|32483359 apoptotic peptidase activating factor 1 isoform c [H... 26 7.7
gi|4502123 apoptotic peptidase activating factor 1 isoform b [Ho... 26 7.7
gi|7108333 apoptotic peptidase activating factor 1 isoform a [Ho... 26 7.7
gi|153792012 DNA polymerase zeta [Homo sapiens] 26 7.7
>gi|197382708 eukaryotic translation initiation factor 4E family
member 3 isoform a [Homo sapiens]
Length = 224
Score = 245 bits (626), Expect = 5e-66
Identities = 118/118 (100%), Positives = 118/118 (100%)
Query: 1 MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV 60
MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV
Sbjct: 107 MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV 166
Query: 61 SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH 118
SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH
Sbjct: 167 SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH 224
>gi|197382664 eukaryotic translation initiation factor 4E family
member 3 isoform b [Homo sapiens]
Length = 118
Score = 245 bits (626), Expect = 5e-66
Identities = 118/118 (100%), Positives = 118/118 (100%)
Query: 1 MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV 60
MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV
Sbjct: 1 MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV 60
Query: 61 SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH 118
SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH
Sbjct: 61 SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH 118
>gi|197382649 eukaryotic translation initiation factor 4E family
member 3 isoform b [Homo sapiens]
Length = 118
Score = 245 bits (626), Expect = 5e-66
Identities = 118/118 (100%), Positives = 118/118 (100%)
Query: 1 MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV 60
MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV
Sbjct: 1 MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV 60
Query: 61 SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH 118
SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH
Sbjct: 61 SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH 118
>gi|27659734 eukaryotic translation initiation factor 4E family
member 3 isoform b [Homo sapiens]
Length = 118
Score = 245 bits (626), Expect = 5e-66
Identities = 118/118 (100%), Positives = 118/118 (100%)
Query: 1 MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV 60
MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV
Sbjct: 1 MRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSV 60
Query: 61 SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH 118
SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH
Sbjct: 61 SVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKH 118
>gi|4757702 eukaryotic translation initiation factor 4E member 2
[Homo sapiens]
Length = 245
Score = 69.3 bits (168), Expect = 6e-13
Identities = 39/117 (33%), Positives = 62/117 (52%), Gaps = 15/117 (12%)
Query: 6 RPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSVSVRDR 65
+P+WE+++N GG W +++ K S W+ L+LA +GEQF +E+ G VSVR +
Sbjct: 121 KPMWEDDANKNGGKWIIRLRKGLASRCWENLILAMLGEQF----MVGEEICGAVVSVRFQ 176
Query: 66 EDVVQVWNVNASLVGEAT------VLEKIYELLPHITFKAVFYKPHEEHHAFEGGRG 116
ED++ +WN AS +AT L ++ L P+ + YK H + G G
Sbjct: 177 EDIISIWNKTAS--DQATTARIRDTLRRVLNLPPNTIME---YKTHTDSIKMPGRLG 228
>gi|194578907 eukaryotic translation initiation factor 4E isoform 3
[Homo sapiens]
Length = 237
Score = 54.3 bits (129), Expect = 2e-08
Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 7 PLWEEESNAKGGVWKMKVPKDSTST----VWKELLLATIGEQFTDCAAADDEVIGVSVSV 62
P+WE+E N +GG W + + K + W E LL IGE F D + D+V G V+V
Sbjct: 120 PMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYS---DDVCGAVVNV 176
Query: 63 RDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVF-YKPHEEHHAFEGGRGKH 118
R + D + +W T + ++Y+ + K V Y+ H + G K+
Sbjct: 177 RAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKN 233
>gi|4503535 eukaryotic translation initiation factor 4E isoform 1
[Homo sapiens]
Length = 217
Score = 54.3 bits (129), Expect = 2e-08
Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 7 PLWEEESNAKGGVWKMKVPKDSTST----VWKELLLATIGEQFTDCAAADDEVIGVSVSV 62
P+WE+E N +GG W + + K + W E LL IGE F D + D+V G V+V
Sbjct: 100 PMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYS---DDVCGAVVNV 156
Query: 63 RDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVF-YKPHEEHHAFEGGRGKH 118
R + D + +W T + ++Y+ + K V Y+ H + G K+
Sbjct: 157 RAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKN 213
>gi|169211405 PREDICTED: similar to hCG1777996 [Homo sapiens]
Length = 217
Score = 54.3 bits (129), Expect = 2e-08
Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 7 PLWEEESNAKGGVWKMKVPKDSTST----VWKELLLATIGEQFTDCAAADDEVIGVSVSV 62
P+WE+E N +GG W + + K + W E LL IGE F D + D+V G V+V
Sbjct: 100 PMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYS---DDVCGAVVNV 156
Query: 63 RDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVF-YKPHEEHHAFEGGRGKH 118
R + D + +W T + ++Y+ + K V Y+ H + G K+
Sbjct: 157 RAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKN 213
>gi|169211874 PREDICTED: similar to hCG1777996 [Homo sapiens]
Length = 217
Score = 54.3 bits (129), Expect = 2e-08
Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 7 PLWEEESNAKGGVWKMKVPKDSTST----VWKELLLATIGEQFTDCAAADDEVIGVSVSV 62
P+WE+E N +GG W + + K + W E LL IGE F D + D+V G V+V
Sbjct: 100 PMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYS---DDVCGAVVNV 156
Query: 63 RDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVF-YKPHEEHHAFEGGRGKH 118
R + D + +W T + ++Y+ + K V Y+ H + G K+
Sbjct: 157 RAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKN 213
>gi|169210992 PREDICTED: hypothetical protein LOC100131693 [Homo
sapiens]
Length = 217
Score = 54.3 bits (129), Expect = 2e-08
Identities = 34/117 (29%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 7 PLWEEESNAKGGVWKMKVPKDSTST----VWKELLLATIGEQFTDCAAADDEVIGVSVSV 62
P+WE+E N +GG W + + K + W E LL IGE F D + D+V G V+V
Sbjct: 100 PMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYS---DDVCGAVVNV 156
Query: 63 RDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVF-YKPHEEHHAFEGGRGKH 118
R + D + +W T + ++Y+ + K V Y+ H + G K+
Sbjct: 157 RAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKN 213
>gi|150378456 eukaryotic translation initiation factor 4E family
member 1B [Homo sapiens]
Length = 242
Score = 48.9 bits (115), Expect = 8e-07
Identities = 29/107 (27%), Positives = 51/107 (47%), Gaps = 8/107 (7%)
Query: 6 RPLWEEESNAKGGVWKMKVPKD----STSTVWKELLLATIGEQFTDCAAADDEVIGVSVS 61
+P+WE+ N +GG W + + K +W E LL IGE F + + EV G V+
Sbjct: 124 QPMWEDSRNKRGGRWLVSLAKQQRHIELDRLWLETLLCLIGESFEEHSR---EVCGAVVN 180
Query: 62 VRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVF-YKPHEE 107
+R + D + VW A + ++Y+ ++ K + Y+ H +
Sbjct: 181 IRTKGDKIAVWTREAENQAGVLHVGRVYKERLGLSPKTIIGYQAHAD 227
>gi|194578909 eukaryotic translation initiation factor 4E isoform 2
[Homo sapiens]
Length = 248
Score = 40.0 bits (92), Expect = 4e-04
Identities = 34/148 (22%), Positives = 55/148 (37%), Gaps = 39/148 (26%)
Query: 7 PLWEEESNAKGGVWKMKVPKDS----------------------TSTVWKEL-------- 36
P+WE+E N +GG W + + K S W ++
Sbjct: 100 PMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETRWDLAMLPRLVSNFWPQVILPLQPPK 159
Query: 37 -----LLATIGEQFTDCAAADDEVIGVSVSVRDREDVVQVWNVNASLVGEATVLEKIYEL 91
LL IGE F D + D+V G V+VR + D + +W T + ++Y+
Sbjct: 160 VLELQLLCLIGESFDDYS---DDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKE 216
Query: 92 LPHITFKAVF-YKPHEEHHAFEGGRGKH 118
+ K V Y+ H + G K+
Sbjct: 217 RLGLPPKIVIGYQSHADTATKSGSTTKN 244
>gi|154350241 brefeldin A-inhibited guanine nucleotide-exchange
protein 3 [Homo sapiens]
Length = 2177
Score = 27.3 bits (59), Expect = 2.6
Identities = 20/43 (46%), Positives = 26/43 (60%), Gaps = 6/43 (13%)
Query: 58 VSVSVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAV 100
+SVSVRD E +Q W N L TVL +I ++LP TF A+
Sbjct: 2102 LSVSVRDAEAQIQAW-TNMVL----TVLNQI-QILPDQTFTAL 2138
>gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo
sapiens]
Length = 1723
Score = 27.3 bits (59), Expect = 2.6
Identities = 13/29 (44%), Positives = 16/29 (55%), Gaps = 2/29 (6%)
Query: 3 GERRPLWEEESNAKGGVWKMKVPKDSTST 31
G R P WEEE + GGVW + S S+
Sbjct: 953 GARHPSWEEEED--GGVWNTTGSQGSASS 979
>gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo
sapiens]
Length = 1029
Score = 27.3 bits (59), Expect = 2.6
Identities = 13/29 (44%), Positives = 16/29 (55%), Gaps = 2/29 (6%)
Query: 3 GERRPLWEEESNAKGGVWKMKVPKDSTST 31
G R P WEEE + GGVW + S S+
Sbjct: 259 GARHPSWEEEED--GGVWNTTGSQGSASS 285
>gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo
sapiens]
Length = 1833
Score = 27.3 bits (59), Expect = 2.6
Identities = 13/29 (44%), Positives = 16/29 (55%), Gaps = 2/29 (6%)
Query: 3 GERRPLWEEESNAKGGVWKMKVPKDSTST 31
G R P WEEE + GGVW + S S+
Sbjct: 1006 GARHPSWEEEED--GGVWNTTGSQGSASS 1032
>gi|31377705 centrosomal protein 97kDa [Homo sapiens]
Length = 865
Score = 26.6 bits (57), Expect = 4.5
Identities = 15/45 (33%), Positives = 21/45 (46%)
Query: 35 ELLLATIGEQFTDCAAADDEVIGVSVSVRDREDVVQVWNVNASLV 79
EL L I D AD+ V G+ V D+E+ +W N + V
Sbjct: 420 ELRLQGINLGLEDDGVADESVKGLESQVLDKEEEQPLWAANENSV 464
>gi|32483361 apoptotic peptidase activating factor 1 isoform d [Homo
sapiens]
Length = 1205
Score = 25.8 bits (55), Expect = 7.7
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 14/62 (22%)
Query: 27 DSTSTVWKELLLATIGEQFTDCAAADDEVIGVSVSVRDR-------EDVVQVWNVNASLV 79
D T V+K A GE+ + A +DEV+ + S DR + V++WN S+
Sbjct: 636 DKTLQVFK----AETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWN---SMT 688
Query: 80 GE 81
GE
Sbjct: 689 GE 690
>gi|32483359 apoptotic peptidase activating factor 1 isoform c [Homo
sapiens]
Length = 1248
Score = 25.8 bits (55), Expect = 7.7
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 14/62 (22%)
Query: 27 DSTSTVWKELLLATIGEQFTDCAAADDEVIGVSVSVRDR-------EDVVQVWNVNASLV 79
D T V+K A GE+ + A +DEV+ + S DR + V++WN S+
Sbjct: 636 DKTLQVFK----AETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWN---SMT 688
Query: 80 GE 81
GE
Sbjct: 689 GE 690
>gi|4502123 apoptotic peptidase activating factor 1 isoform b [Homo
sapiens]
Length = 1194
Score = 25.8 bits (55), Expect = 7.7
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 14/62 (22%)
Query: 27 DSTSTVWKELLLATIGEQFTDCAAADDEVIGVSVSVRDR-------EDVVQVWNVNASLV 79
D T V+K A GE+ + A +DEV+ + S DR + V++WN S+
Sbjct: 625 DKTLQVFK----AETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWN---SMT 677
Query: 80 GE 81
GE
Sbjct: 678 GE 679
>gi|7108333 apoptotic peptidase activating factor 1 isoform a [Homo
sapiens]
Length = 1237
Score = 25.8 bits (55), Expect = 7.7
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 14/62 (22%)
Query: 27 DSTSTVWKELLLATIGEQFTDCAAADDEVIGVSVSVRDR-------EDVVQVWNVNASLV 79
D T V+K A GE+ + A +DEV+ + S DR + V++WN S+
Sbjct: 625 DKTLQVFK----AETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWN---SMT 677
Query: 80 GE 81
GE
Sbjct: 678 GE 679
>gi|153792012 DNA polymerase zeta [Homo sapiens]
Length = 3130
Score = 25.8 bits (55), Expect = 7.7
Identities = 11/26 (42%), Positives = 16/26 (61%)
Query: 83 TVLEKIYELLPHITFKAVFYKPHEEH 108
T++++I ELL FY+PHE H
Sbjct: 131 TMVKRICELLQSGAIMNKFYQPHEAH 156
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,597,119
Number of Sequences: 37866
Number of extensions: 165808
Number of successful extensions: 349
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 314
Number of HSP's gapped (non-prelim): 29
length of query: 118
length of database: 18,247,518
effective HSP length: 88
effective length of query: 30
effective length of database: 14,915,310
effective search space: 447459300
effective search space used: 447459300
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.