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Search of human proteins with 27597090
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]
(1726 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27597090 suppressor of Ty 6 homolog [Homo sapiens] 3508 0.0
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 82 5e-15
gi|221136781 S1 RNA binding domain 1 [Homo sapiens] 72 5e-12
gi|55956788 nucleolin [Homo sapiens] 71 8e-12
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 69 3e-11
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 69 3e-11
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 69 3e-11
gi|210032580 SET domain containing 1B [Homo sapiens] 69 5e-11
gi|24415404 MDN1, midasin homolog [Homo sapiens] 67 2e-10
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 62 5e-09
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 60 2e-08
gi|148746195 trichohyalin [Homo sapiens] 60 2e-08
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 60 2e-08
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 59 3e-08
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 59 3e-08
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 58 7e-08
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 58 7e-08
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 58 7e-08
gi|4504487 histidine rich calcium binding protein precursor [Hom... 58 7e-08
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 57 1e-07
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo... 57 1e-07
gi|217330641 IWS1 homolog [Homo sapiens] 57 2e-07
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 57 2e-07
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 57 2e-07
gi|21735415 centromere protein B [Homo sapiens] 56 3e-07
gi|31317305 M-phase phosphoprotein 10 [Homo sapiens] 56 3e-07
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 56 3e-07
gi|19923844 coiled-coil domain containing 82 [Homo sapiens] 56 3e-07
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 55 5e-07
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 55 5e-07
>gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]
Length = 1726
Score = 3508 bits (9097), Expect = 0.0
Identities = 1726/1726 (100%), Positives = 1726/1726 (100%)
Query: 1 MSDFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFIND 60
MSDFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFIND
Sbjct: 1 MSDFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFIND 60
Query: 61 DDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRR 120
DDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRR
Sbjct: 61 DDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRR 120
Query: 121 VKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESD 180
VKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESD
Sbjct: 121 VKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESD 180
Query: 181 IDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEY 240
IDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEY
Sbjct: 181 IDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEY 240
Query: 241 EYEDDEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEIRATDLPERFQL 300
EYEDDEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEIRATDLPERFQL
Sbjct: 241 EYEDDEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEIRATDLPERFQL 300
Query: 301 RSIPVKGAEDDELEEEADWIYRNAFATPTISLQESCDYLDRGQPASSFSRKGPSTIQKIK 360
RSIPVKGAEDDELEEEADWIYRNAFATPTISLQESCDYLDRGQPASSFSRKGPSTIQKIK
Sbjct: 301 RSIPVKGAEDDELEEEADWIYRNAFATPTISLQESCDYLDRGQPASSFSRKGPSTIQKIK 360
Query: 361 EALGFMRNQHFEVPFIAFYRKEYVEPELHINDLWRVWQWDEKWTQLRIRKENLTRLFEKM 420
EALGFMRNQHFEVPFIAFYRKEYVEPELHINDLWRVWQWDEKWTQLRIRKENLTRLFEKM
Sbjct: 361 EALGFMRNQHFEVPFIAFYRKEYVEPELHINDLWRVWQWDEKWTQLRIRKENLTRLFEKM 420
Query: 421 QAYQYEQISADPDKPLADGIRALDTTDMERLKDVQSMDELKDVYNHFLLYYGRDIPKMQN 480
QAYQYEQISADPDKPLADGIRALDTTDMERLKDVQSMDELKDVYNHFLLYYGRDIPKMQN
Sbjct: 421 QAYQYEQISADPDKPLADGIRALDTTDMERLKDVQSMDELKDVYNHFLLYYGRDIPKMQN 480
Query: 481 AAKASRKKLKRVREEGDEEGEGDEAEDEEQRGPELKQASRRDMYTICQSAGLDGLAKKFG 540
AAKASRKKLKRVREEGDEEGEGDEAEDEEQRGPELKQASRRDMYTICQSAGLDGLAKKFG
Sbjct: 481 AAKASRKKLKRVREEGDEEGEGDEAEDEEQRGPELKQASRRDMYTICQSAGLDGLAKKFG 540
Query: 541 LTPEQFGENLRDSYQRHETEQFPAEPLELAKDYVCSQFPTPEAVLEGARYMVALQIAREP 600
LTPEQFGENLRDSYQRHETEQFPAEPLELAKDYVCSQFPTPEAVLEGARYMVALQIAREP
Sbjct: 541 LTPEQFGENLRDSYQRHETEQFPAEPLELAKDYVCSQFPTPEAVLEGARYMVALQIAREP 600
Query: 601 LVRQVLRQTFQERAKLNITPTKKGRKDVDEAHYAYSFKYLKNKPVKELRDDQFLKICLAE 660
LVRQVLRQTFQERAKLNITPTKKGRKDVDEAHYAYSFKYLKNKPVKELRDDQFLKICLAE
Sbjct: 601 LVRQVLRQTFQERAKLNITPTKKGRKDVDEAHYAYSFKYLKNKPVKELRDDQFLKICLAE 660
Query: 661 DEGLLTTDISIDLKGVEGYGNDQTYFEEIKQFYYRDEFSHQVQEWNRQRTMAIERALQQF 720
DEGLLTTDISIDLKGVEGYGNDQTYFEEIKQFYYRDEFSHQVQEWNRQRTMAIERALQQF
Sbjct: 661 DEGLLTTDISIDLKGVEGYGNDQTYFEEIKQFYYRDEFSHQVQEWNRQRTMAIERALQQF 720
Query: 721 LYVQMAKELKNKLLAEAKEYVIKACSRKLYNWLRVAPYRPDQQVEEDDDFMDENQGKGIR 780
LYVQMAKELKNKLLAEAKEYVIKACSRKLYNWLRVAPYRPDQQVEEDDDFMDENQGKGIR
Sbjct: 721 LYVQMAKELKNKLLAEAKEYVIKACSRKLYNWLRVAPYRPDQQVEEDDDFMDENQGKGIR 780
Query: 781 VLGIAFSSARDHPVFCALVNGEGEVTDFLRLPHFTKRRTAWREEEREKKAQDIETLKKFL 840
VLGIAFSSARDHPVFCALVNGEGEVTDFLRLPHFTKRRTAWREEEREKKAQDIETLKKFL
Sbjct: 781 VLGIAFSSARDHPVFCALVNGEGEVTDFLRLPHFTKRRTAWREEEREKKAQDIETLKKFL 840
Query: 841 LNKKPHVVTVAGENRDAQMLIEDVKRIVHELDQGQQLSSIGVELVDNELAILYMNSKKSE 900
LNKKPHVVTVAGENRDAQMLIEDVKRIVHELDQGQQLSSIGVELVDNELAILYMNSKKSE
Sbjct: 841 LNKKPHVVTVAGENRDAQMLIEDVKRIVHELDQGQQLSSIGVELVDNELAILYMNSKKSE 900
Query: 901 AEFRDYPPVLRQAVSLARRIQDPLIEFAQVCSSDEDILCLKFHPLQEHVVKEELLNALYC 960
AEFRDYPPVLRQAVSLARRIQDPLIEFAQVCSSDEDILCLKFHPLQEHVVKEELLNALYC
Sbjct: 901 AEFRDYPPVLRQAVSLARRIQDPLIEFAQVCSSDEDILCLKFHPLQEHVVKEELLNALYC 960
Query: 961 EFINRVNEVGVDVNRAIAHPYSQALIQYVCGLGPRKGTHLLKILKQNNTRLESRTQLVTM 1020
EFINRVNEVGVDVNRAIAHPYSQALIQYVCGLGPRKGTHLLKILKQNNTRLESRTQLVTM
Sbjct: 961 EFINRVNEVGVDVNRAIAHPYSQALIQYVCGLGPRKGTHLLKILKQNNTRLESRTQLVTM 1020
Query: 1021 CHMGPKVFMNCAGFLKIDTASLGDSTDSYIEVLDGSRVHPETYEWARKMAVDALEYDESA 1080
CHMGPKVFMNCAGFLKIDTASLGDSTDSYIEVLDGSRVHPETYEWARKMAVDALEYDESA
Sbjct: 1021 CHMGPKVFMNCAGFLKIDTASLGDSTDSYIEVLDGSRVHPETYEWARKMAVDALEYDESA 1080
Query: 1081 EDANPAGALEEILENPERLKDLDLDAFAEELERQGYGDKHITLYDIRAELSCRYKDLRTA 1140
EDANPAGALEEILENPERLKDLDLDAFAEELERQGYGDKHITLYDIRAELSCRYKDLRTA
Sbjct: 1081 EDANPAGALEEILENPERLKDLDLDAFAEELERQGYGDKHITLYDIRAELSCRYKDLRTA 1140
Query: 1141 YRSPNTEEIFNMLTKETPETFYIGKLIICNVTGIAHRRPQGESYDQAIRNDETGLWQCPF 1200
YRSPNTEEIFNMLTKETPETFYIGKLIICNVTGIAHRRPQGESYDQAIRNDETGLWQCPF
Sbjct: 1141 YRSPNTEEIFNMLTKETPETFYIGKLIICNVTGIAHRRPQGESYDQAIRNDETGLWQCPF 1200
Query: 1201 CQQDNFPELSEVWNHFDSGSCPGQAIGVKTRLDNGVTGFIPTKFLSDKVVKRPEERVKVG 1260
CQQDNFPELSEVWNHFDSGSCPGQAIGVKTRLDNGVTGFIPTKFLSDKVVKRPEERVKVG
Sbjct: 1201 CQQDNFPELSEVWNHFDSGSCPGQAIGVKTRLDNGVTGFIPTKFLSDKVVKRPEERVKVG 1260
Query: 1261 MTVHCRIMKIDIEKFSADLTCRTSDLMDRNNEWKLPKDTYYDFDAEAADHKQEEDMKRKQ 1320
MTVHCRIMKIDIEKFSADLTCRTSDLMDRNNEWKLPKDTYYDFDAEAADHKQEEDMKRKQ
Sbjct: 1261 MTVHCRIMKIDIEKFSADLTCRTSDLMDRNNEWKLPKDTYYDFDAEAADHKQEEDMKRKQ 1320
Query: 1321 QRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVIIRPSSKGENHLTVTWKVSDGIYQH 1380
QRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVIIRPSSKGENHLTVTWKVSDGIYQH
Sbjct: 1321 QRTTYIKRVIAHPSFHNINFKQAEKMMETMDQGDVIIRPSSKGENHLTVTWKVSDGIYQH 1380
Query: 1381 VDVREEGKENAFSLGATLWINSEEFEDLDEIVARYVQPMASFARDLLNHKYYQDCSGGDR 1440
VDVREEGKENAFSLGATLWINSEEFEDLDEIVARYVQPMASFARDLLNHKYYQDCSGGDR
Sbjct: 1381 VDVREEGKENAFSLGATLWINSEEFEDLDEIVARYVQPMASFARDLLNHKYYQDCSGGDR 1440
Query: 1441 KKLEELLIKTKKEKPTFIPYFICACKELPGKFLLGYQPRGKPRIEYVTVTPEGFRYRGQI 1500
KKLEELLIKTKKEKPTFIPYFICACKELPGKFLLGYQPRGKPRIEYVTVTPEGFRYRGQI
Sbjct: 1441 KKLEELLIKTKKEKPTFIPYFICACKELPGKFLLGYQPRGKPRIEYVTVTPEGFRYRGQI 1500
Query: 1501 FPTVNGLFRWFKDHYQDPVPGITPSSSSRTRTPASINATPANINLADLTRAVNALPQNMT 1560
FPTVNGLFRWFKDHYQDPVPGITPSSSSRTRTPASINATPANINLADLTRAVNALPQNMT
Sbjct: 1501 FPTVNGLFRWFKDHYQDPVPGITPSSSSRTRTPASINATPANINLADLTRAVNALPQNMT 1560
Query: 1561 SQMFSAIAAVTGQGQNPNATPAQWASSQYGYGGSGGGSSAYHVFPTPAQQPVATPLMTPS 1620
SQMFSAIAAVTGQGQNPNATPAQWASSQYGYGGSGGGSSAYHVFPTPAQQPVATPLMTPS
Sbjct: 1561 SQMFSAIAAVTGQGQNPNATPAQWASSQYGYGGSGGGSSAYHVFPTPAQQPVATPLMTPS 1620
Query: 1621 YSYTTPSQPITTPQYHQLQASTTPQSAQAQPQPSSSSRQRQQQPKSNSHAAIDWGKMAEQ 1680
YSYTTPSQPITTPQYHQLQASTTPQSAQAQPQPSSSSRQRQQQPKSNSHAAIDWGKMAEQ
Sbjct: 1621 YSYTTPSQPITTPQYHQLQASTTPQSAQAQPQPSSSSRQRQQQPKSNSHAAIDWGKMAEQ 1680
Query: 1681 WLQEKEAERRKQKQRLTPRPSPSPMIESTPMSIAGDATPLLDEMDR 1726
WLQEKEAERRKQKQRLTPRPSPSPMIESTPMSIAGDATPLLDEMDR
Sbjct: 1681 WLQEKEAERRKQKQRLTPRPSPSPMIESTPMSIAGDATPLLDEMDR 1726
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 82.0 bits (201), Expect = 5e-15
Identities = 77/265 (29%), Positives = 123/265 (46%), Gaps = 43/265 (16%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDED 65
E E EE E E +EGE + EEE + E EEE + ++E+G KG ++ E
Sbjct: 877 EGEEEEGEGEGEEEGE------GEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEG 930
Query: 66 EGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMS 125
EGEE+EG G+ ED G + + ++ E+ + + EE G G++ +
Sbjct: 931 EGEEEEGE--GEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEG----EGEEGEGEGEEE 984
Query: 126 DDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEA-MEAPMAPPEEEEEDDEESDIDDF 184
+ E + EEE G+EE E+E EE +GEGEE +E +E + E E E +EE
Sbjct: 985 EGEGEGEEEEGEEEGEEEGEGEEE-GEGEGEEEEEGEVEGEVEGEEGEGEGEEEEG---- 1039
Query: 185 IVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEYED 244
+++G+ +K G + +E +E E+ +Y E EEE E +D
Sbjct: 1040 --EEEGEEREKEG-----EGEENRRNREEEE-----------EEEGKYQETGEEENERQD 1081
Query: 245 DE-------AEGEIRVRPKKTTKKR 262
E +G ++ KT +K+
Sbjct: 1082 GEEYKKVSKIKGSVKYGKHKTYQKK 1106
Score = 76.6 bits (187), Expect = 2e-13
Identities = 75/283 (26%), Positives = 125/283 (44%), Gaps = 6/283 (2%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDED 65
E EE EE EG V + EEE++ E EEEE + ++E+G + + E+
Sbjct: 802 EGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEG-EGEEEEGEGEEEEGEGKGEE 860
Query: 66 EGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMS 125
EGEE EG + G+ + G ++ ++ E + + E G + G+ +
Sbjct: 861 EGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGK 920
Query: 126 DDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFI 185
+E+ +E E EE E E E+ +GE EEG+ E E EEE + E + +
Sbjct: 921 GEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGE 980
Query: 186 VDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEYEDD 245
+++ + + + G + +E E G + + E E E EE E E E E+
Sbjct: 981 GEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVE-GEEGEGEGEEEEG 1039
Query: 246 EAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNE 288
E EGE R + + + R +R E E E + +++NE
Sbjct: 1040 EEEGEEREKEGEGEENRRNR----EEEEEEEGKYQETGEEENE 1078
Score = 69.7 bits (169), Expect = 2e-11
Identities = 71/248 (28%), Positives = 113/248 (45%), Gaps = 29/248 (11%)
Query: 8 EAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQG-NLKGFINDDDDEDE 66
E EE EE + EGE EE D +EEEE+E ++ +G ++G ++ E +
Sbjct: 726 EMEEGGEEEHGEGEE---------EEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERK 776
Query: 67 GEEDEG-SDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMS 125
EE G + G+ E D G + + T + R E+ + E V+ +G++ ++
Sbjct: 777 KEERAGKEEKGEEEGDQGEGEEEET--EGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGE 834
Query: 126 DDEDD---DEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDID 182
+E++ +EEE EE E E EE ++GEGEE E E E E E +EE + +
Sbjct: 835 GEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGE 894
Query: 183 DFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEY 242
+ +G+ ++ + E +E G +E E+ EE E E E
Sbjct: 895 GEEEEGEGEGEEEGE-------------GEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEG 941
Query: 243 EDDEAEGE 250
ED E EGE
Sbjct: 942 EDGEGEGE 949
Score = 61.2 bits (147), Expect = 8e-09
Identities = 62/246 (25%), Positives = 117/246 (47%), Gaps = 17/246 (6%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDED 65
+ E ++ E GE + +K ++ D EE+E++ + EQG+ K + + +
Sbjct: 676 KGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQK----EREQGHQK---ERNQEME 728
Query: 66 EGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMS 125
EG E+E G+ E++ G ++ + + E+ + + +E + +K R K
Sbjct: 729 EGGEEE---HGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEE 785
Query: 126 DDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFI 185
E++ ++ G+EE E E EE + GE E G+ +E EEEEE+ E + +
Sbjct: 786 KGEEEGDQGEGEEE-ETEGRGEEKEEGGEVEGGE--VEEGKGEREEEEEEGEGEEEEGEG 842
Query: 186 VDDDGQ-PLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEYED 244
+++G+ ++ + + + G +E +E G + +E E E +EE E E E E+
Sbjct: 843 EEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEG---EGEEEEGEGEGEEEGEGEGEEEE 899
Query: 245 DEAEGE 250
E EGE
Sbjct: 900 GEGEGE 905
Score = 58.5 bits (140), Expect = 5e-08
Identities = 55/250 (22%), Positives = 114/250 (45%), Gaps = 17/250 (6%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDED 65
+ + E ++ D+ EV K E ED E D E+G+ D++ +
Sbjct: 620 KEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRG----DGTCEEGSSGAEHWQDEERE 675
Query: 66 EGEEDEGSDS----GDSEDDVGHKKR-KRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRR 120
+GE+D+G G+ E ++ K+ K+ +++ + + ++ +++ G +
Sbjct: 676 KGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEH 735
Query: 121 VKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESD 180
+ ++ D +EEE + E ++E EE+ + E EEG+ E E+ EE+ ++ +
Sbjct: 736 GEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGE 795
Query: 181 IDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEY 240
++ + +G+ +K + + G + E +E + +E E E E EEE
Sbjct: 796 GEE--EETEGRGEEKEEGGEVEGGEVEEGKGEREE------EEEEGEGEEEEGEGEEEEG 847
Query: 241 EYEDDEAEGE 250
E E++E EG+
Sbjct: 848 EGEEEEGEGK 857
Score = 55.8 bits (133), Expect = 3e-07
Identities = 45/177 (25%), Positives = 87/177 (49%), Gaps = 30/177 (16%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTK-KFVEEEDDDEEEEEENLD----------------DQ 48
E E EE E E +EGE + + EEE + E EEEE + ++
Sbjct: 956 EGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEE 1015
Query: 49 DEQGNLKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENL 108
+E+G ++G + ++ E EGEE+EG + G+ + G + R + ++ E+++ +E
Sbjct: 1016 EEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREE--EEEEEGKYQETG 1073
Query: 109 GVKVKR--GQKYRRVKKMSDDEDDDEEEYGKEE-HEKEAIAEEIFQDGEGEEGQEAM 162
+ +R G++Y++V K+ +YGK + ++K+++ G G+E + M
Sbjct: 1074 EEENERQDGEEYKKVSKIK-----GSVKYGKHKTYQKKSVTN---TQGNGKEQRSKM 1122
Score = 54.3 bits (129), Expect = 1e-06
Identities = 60/250 (24%), Positives = 110/250 (44%), Gaps = 17/250 (6%)
Query: 10 EESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLD---------DQDEQGNLKGFIND 60
EE E E N+E V K+ E DD ++ E + + +G G +
Sbjct: 602 EEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEE 661
Query: 61 DDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRR 120
E +DE + G+ + G +R + E +++ + + +R Q +++
Sbjct: 662 GSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQK 721
Query: 121 VKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESD 180
++ + E+ EEE+G+ E E+ EE ++GEG+E E E E E+E+ E
Sbjct: 722 -ERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEE---VEGEREKEEGERKK 777
Query: 181 IDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEY 240
+ ++ G+ ++ + T+ +E +E G + + E E+ EE EEE
Sbjct: 778 EERAGKEEKGE--EEGDQGEGEEEETEGRGEEKEE--GGEVEGGEVEEGKGEREEEEEEG 833
Query: 241 EYEDDEAEGE 250
E E++E EGE
Sbjct: 834 EGEEEEGEGE 843
Score = 31.6 bits (70), Expect = 7.0
Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 4/93 (4%)
Query: 472 GRDIPKMQNAAKASRKKLKRV--REEGDEEGEGDEAEDEEQ--RGPELKQASRRDMYTIC 527
G ++ + + RKK +R E+G+EEG+ E E+EE RG E ++ + +
Sbjct: 761 GEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVE 820
Query: 528 QSAGLDGLAKKFGLTPEQFGENLRDSYQRHETE 560
+ G ++ G E+ GE + + E E
Sbjct: 821 EGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEE 853
>gi|221136781 S1 RNA binding domain 1 [Homo sapiens]
Length = 995
Score = 72.0 bits (175), Expect = 5e-12
Identities = 107/475 (22%), Positives = 192/475 (40%), Gaps = 96/475 (20%)
Query: 587 GARYMVALQIAREPLVRQVLRQTFQER------AKLNITPTKKGRKDVDEAHYAYSFKYL 640
G ++++A IA++ +R Q+R + ++ K KDVD+ F
Sbjct: 368 GVQHILADMIAKDKDTLDFIRNLCQKRHVCIQSSLAKVSSKKVNEKDVDKFLLYQHFSC- 426
Query: 641 KNKPVKELRDDQFLKICLAEDEGLLTTDISIDLKGVEGYGNDQTYFEEIKQFYYRDEFSH 700
++ + Q L I E+ +LT ++I GV +DEF
Sbjct: 427 ---NIRNIHHHQILAINRGENLKVLTVKVNIS-DGV------------------KDEFCR 464
Query: 701 Q-VQEWNRQRTMA-----------IERALQQFLYVQMAKELKNKLLAEAKEYVIKACSRK 748
+Q R R+ A + + ++ +Y + +E + KL ++A++ + R
Sbjct: 465 WCIQNRWRPRSFARPELMKILYNSLNDSFKRLIYPLLCREFRAKLTSDAEKESVMMFGRN 524
Query: 749 LYNWLRVAPYRPDQQVEEDDDFMDENQGKGIRVLGIAFSSARDHPVFCALVNGEGEVTDF 808
L L +P P + + +D G ++ I+ +S H L G+G
Sbjct: 525 LRQLLLTSPV-PGRTLMG----VDPGYKHGCKLAIISPTSQILHTDVVYLHCGQG----- 574
Query: 809 LRLPHFTKRRTAWREEEREKKAQDIETLKKFLLNKKPHVVTVAGEN--RDAQMLIEDV-- 864
+RE E+ +K LLN V + R+ + D+
Sbjct: 575 ------------FREAEK---------IKTLLLNFNCSTVVIGNGTACRETEAYFADLIM 613
Query: 865 KRIVHELDQGQQLSSIGVELVDNELAILYMNSKKSEAEFRDYPPVLRQAVSLARRIQDPL 924
K LD + +V A +Y S ++ E P LR AVS+ARR+QDPL
Sbjct: 614 KNYFAPLD-------VVYCIVSEAGASIYSVSPEANKEMPGLDPNLRSAVSIARRVQDPL 666
Query: 925 IEFAQVCSSDEDILCLKFHPLQEHVVKEELLNALYCEFINR-VNEVGVDVNRAIAHPYSQ 983
E ++ + + +H V + LL A + V+ VGVD+N S+
Sbjct: 667 AELVKIEPKHIGV------GMYQHDVSQTLLKATLDSVVEECVSFVGVDINIC-----SE 715
Query: 984 ALIQYVCGLGPRKGTHLLKILKQNNTRLESRTQLVTMCHMGPKVFMNCAGFLKID 1038
L++++ GL + ++++ ++ N +R QL + +GPK F CAGF++I+
Sbjct: 716 VLLRHIAGLNANRAKNIIE-WREKNGPFINREQLKKVKGLGPKSFQQCAGFIRIN 769
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 71.2 bits (173), Expect = 8e-12
Identities = 68/293 (23%), Positives = 126/293 (43%), Gaps = 51/293 (17%)
Query: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDD 62
D E + E+ E+E DE E+ P K ++E++E++ DD+D DDD
Sbjct: 151 DDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDED----------DDD 200
Query: 63 DEDEGEEDEGSDS----GDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKY 118
DE++ E+E ++ G V K K + D+ E+DD D +++
Sbjct: 201 DEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDD----------- 249
Query: 119 RRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEE--EDD 176
DDEDDD+E+ +EE E+E EE ++ G+ +E + AP +++ E
Sbjct: 250 -----DEDDEDDDDEDDEEEEEEEE---EEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGT 301
Query: 177 EESDIDDFIVDDDGQPLKKPKWRKKLP---GYTDAALQEAQEIFGVDFDYDEFEKYNEYD 233
E + + V + P+ + + D A+ + + F Y +FE + +
Sbjct: 302 EPTTAFNLFVGNLNFNKSAPELKTGISDVFAKNDLAVVDVRIGMTRKFGYVDFESAEDLE 361
Query: 234 EELE-------------EEYEYEDDEAEGEIRVRPKKTTKKRVSRRSIFEMYE 273
+ LE E+ + +D + E + R K +V++ + E++E
Sbjct: 362 KALELTGLKVFGNEIKLEKPKGKDSKKERDARTLLAKNLPYKVTQDELKEVFE 414
Score = 67.0 bits (162), Expect = 2e-10
Identities = 50/171 (29%), Positives = 83/171 (48%), Gaps = 39/171 (22%)
Query: 7 SEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDEDE 66
++ E+S+EE +D+ E E+E+DDE+E+E+ +D+ E +K EDE
Sbjct: 140 AKKEDSDEEEDDDSE----------EDEEDDEDEDED--EDEIEPAAMKAAAAAPASEDE 187
Query: 67 GEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMSD 126
+ED+ D D +D+ EDD + E K K+ K VK +
Sbjct: 188 DDEDDEDDEDDDDDE---------------EDDSEEEAMETTPAKGKKAAKVVPVKAKNV 232
Query: 127 DEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDE 177
ED+DEEE ++E + + +E +D + E+ +E EEEEE++E
Sbjct: 233 AEDEDEEEDDEDEDDDD---DEDDEDDDDEDDEE---------EEEEEEEE 271
Score = 60.5 bits (145), Expect = 1e-08
Identities = 44/156 (28%), Positives = 78/156 (50%), Gaps = 18/156 (11%)
Query: 122 KKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPP---EEEEEDDEE 178
K+ SD+E+DD+ E +E+ E E + E E AM+A A P +E++EDDE+
Sbjct: 142 KEDSDEEEDDDSEEDEEDDEDE-------DEDEDEIEPAAMKAAAAAPASEDEDDEDDED 194
Query: 179 SDIDDFIVDDDGQ-------PLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNE 231
+ DD +DD + P K K K +P ++ E D D D+ + ++
Sbjct: 195 DEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEED-DEDEDDDDDEDD 253
Query: 232 YDEELEEEYEYEDDEAEGEIRVRPKKTTKKRVSRRS 267
D++ E++ E E++E E ++ P K K+ +++
Sbjct: 254 EDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKA 289
Score = 52.8 bits (125), Expect = 3e-06
Identities = 39/139 (28%), Positives = 65/139 (46%), Gaps = 24/139 (17%)
Query: 53 NLKGFINDDDDEDEGEEDE--GSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGV 110
N K +D++++D+ EEDE D + ED++ K + ED+D + E
Sbjct: 139 NAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDE----- 193
Query: 111 KVKRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPE 170
DDEDDD++E +++ E+EA+ + + + +A E
Sbjct: 194 ---------------DDEDDDDDE--EDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDE 236
Query: 171 EEEEDDEESDIDDFIVDDD 189
+EEEDDE+ D DD D+D
Sbjct: 237 DEEEDDEDEDDDDDEDDED 255
Score = 35.8 bits (81), Expect = 0.37
Identities = 43/179 (24%), Positives = 73/179 (40%), Gaps = 42/179 (23%)
Query: 144 AIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLKKPKWRKKLP 203
AI + ++G+ + +++ E EE+EEDDE+ D D +D+ +P
Sbjct: 128 AIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDED----EDEIEP----------- 172
Query: 204 GYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEYEDDEAEGEIRVRPKKTTKKR- 262
AA++ A + + DE ++ +E D++ E EDD E + P K K
Sbjct: 173 ----AAMKAAAAAPASEDEDDEDDEDDEDDDDDE-----EDDSEEEAMETTPAKGKKAAK 223
Query: 263 ---VSRRSIFEMYEPSELESSHLTDQDNEIRATDLPERFQLRSIPVKGAEDDELEEEAD 318
V +++ E + E + D D + D EDDE EEE +
Sbjct: 224 VVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDD--------------DEDDEEEEEEE 268
>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member E isoform 1 [Homo sapiens]
Length = 268
Score = 69.3 bits (168), Expect = 3e-11
Identities = 44/132 (33%), Positives = 69/132 (52%), Gaps = 14/132 (10%)
Query: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDD 62
D ++EA +SEEE +++G+ EDD+EEEE E + + + +D+
Sbjct: 149 DQEDNEAPDSEEEDDEDGD------------EDDEEEEENEAGPPEGYEEEEEEEEEEDE 196
Query: 63 DEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVK 122
DEDE E++ GS+ G+ E++VG + D E+DD D +EE + + R K
Sbjct: 197 DEDEDEDEAGSELGEGEEEVGLSYLMKEEIQD--EEDDDDYVEEGEEEEEEEEGGLRGEK 254
Query: 123 KMSDDEDDDEEE 134
+ D EDD EEE
Sbjct: 255 RKRDAEDDGEEE 266
Score = 57.8 bits (138), Expect = 9e-08
Identities = 33/112 (29%), Positives = 60/112 (53%), Gaps = 14/112 (12%)
Query: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGN--------- 53
D E + E+ +E+ +E E + + EEE+++EEE+E+ +D+DE G+
Sbjct: 157 DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 216
Query: 54 -----LKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDD 100
+K I D++D+D+ E+ + + E + +KRKR + DD E+DD
Sbjct: 217 GLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 268
Score = 53.5 bits (127), Expect = 2e-06
Identities = 47/176 (26%), Positives = 82/176 (46%), Gaps = 28/176 (15%)
Query: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDD 62
D E E+ E++ ++T +++ D ++ E ++ ++ DE G D+D
Sbjct: 119 DLFNCEITNLEDYRESIFELLQQIT--YLDGFDQEDNEAPDSEEEDDEDG-------DED 169
Query: 63 DEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGV-KVKRGQKYRRV 121
DE+E E + G G E++ ++ +D ED+D D LG + + G Y
Sbjct: 170 DEEEEENEAGPPEGYEEEEEEEEE------EDEDEDEDEDEAGSELGEGEEEVGLSYLMK 223
Query: 122 KKMSDDEDDDE-EEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDD 176
+++ D+EDDD+ E G+EE E+E G G++ A + EEEDD
Sbjct: 224 EEIQDEEDDDDYVEEGEEEEEEEE---------GGLRGEKRKRD--AEDDGEEEDD 268
Score = 48.5 bits (114), Expect = 6e-05
Identities = 35/123 (28%), Positives = 59/123 (47%), Gaps = 14/123 (11%)
Query: 135 YGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLK 194
+ +E++E EE +DG+ E+ +E E PPE EE++EE + +D D+D
Sbjct: 148 FDQEDNEAPDSEEEDDEDGD-EDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE-- 204
Query: 195 KPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEYEDDEAEGEIRVR 254
+ L E +E G+ + E + E D++ EE E E++E EG +R
Sbjct: 205 -----------AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 253
Query: 255 PKK 257
+K
Sbjct: 254 KRK 256
>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
Length = 227
Score = 69.3 bits (168), Expect = 3e-11
Identities = 44/132 (33%), Positives = 69/132 (52%), Gaps = 14/132 (10%)
Query: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDD 62
D ++EA +SEEE +++G+ EDD+EEEE E + + + +D+
Sbjct: 108 DQEDNEAPDSEEEDDEDGD------------EDDEEEEENEAGPPEGYEEEEEEEEEEDE 155
Query: 63 DEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVK 122
DEDE E++ GS+ G+ E++VG + D E+DD D +EE + + R K
Sbjct: 156 DEDEDEDEAGSELGEGEEEVGLSYLMKEEIQD--EEDDDDYVEEGEEEEEEEEGGLRGEK 213
Query: 123 KMSDDEDDDEEE 134
+ D EDD EEE
Sbjct: 214 RKRDAEDDGEEE 225
Score = 57.8 bits (138), Expect = 9e-08
Identities = 33/112 (29%), Positives = 60/112 (53%), Gaps = 14/112 (12%)
Query: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGN--------- 53
D E + E+ +E+ +E E + + EEE+++EEE+E+ +D+DE G+
Sbjct: 116 DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 175
Query: 54 -----LKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDD 100
+K I D++D+D+ E+ + + E + +KRKR + DD E+DD
Sbjct: 176 GLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 227
Score = 53.5 bits (127), Expect = 2e-06
Identities = 47/176 (26%), Positives = 82/176 (46%), Gaps = 28/176 (15%)
Query: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDD 62
D E E+ E++ ++T +++ D ++ E ++ ++ DE G D+D
Sbjct: 78 DLFNCEITNLEDYRESIFELLQQIT--YLDGFDQEDNEAPDSEEEDDEDG-------DED 128
Query: 63 DEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGV-KVKRGQKYRRV 121
DE+E E + G G E++ ++ +D ED+D D LG + + G Y
Sbjct: 129 DEEEEENEAGPPEGYEEEEEEEEE------EDEDEDEDEDEAGSELGEGEEEVGLSYLMK 182
Query: 122 KKMSDDEDDDE-EEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDD 176
+++ D+EDDD+ E G+EE E+E G G++ A + EEEDD
Sbjct: 183 EEIQDEEDDDDYVEEGEEEEEEEE---------GGLRGEKRKRD--AEDDGEEEDD 227
Score = 48.5 bits (114), Expect = 6e-05
Identities = 35/123 (28%), Positives = 59/123 (47%), Gaps = 14/123 (11%)
Query: 135 YGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLK 194
+ +E++E EE +DG+ E+ +E E PPE EE++EE + +D D+D
Sbjct: 107 FDQEDNEAPDSEEEDDEDGD-EDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE-- 163
Query: 195 KPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEYEDDEAEGEIRVR 254
+ L E +E G+ + E + E D++ EE E E++E EG +R
Sbjct: 164 -----------AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 212
Query: 255 PKK 257
+K
Sbjct: 213 KRK 215
>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 3 [Homo sapiens]
Length = 220
Score = 69.3 bits (168), Expect = 3e-11
Identities = 44/132 (33%), Positives = 69/132 (52%), Gaps = 14/132 (10%)
Query: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDD 62
D ++EA +SEEE +++G+ EDD+EEEE E + + + +D+
Sbjct: 101 DQEDNEAPDSEEEDDEDGD------------EDDEEEEENEAGPPEGYEEEEEEEEEEDE 148
Query: 63 DEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVK 122
DEDE E++ GS+ G+ E++VG + D E+DD D +EE + + R K
Sbjct: 149 DEDEDEDEAGSELGEGEEEVGLSYLMKEEIQD--EEDDDDYVEEGEEEEEEEEGGLRGEK 206
Query: 123 KMSDDEDDDEEE 134
+ D EDD EEE
Sbjct: 207 RKRDAEDDGEEE 218
Score = 57.8 bits (138), Expect = 9e-08
Identities = 33/112 (29%), Positives = 60/112 (53%), Gaps = 14/112 (12%)
Query: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGN--------- 53
D E + E+ +E+ +E E + + EEE+++EEE+E+ +D+DE G+
Sbjct: 109 DSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEV 168
Query: 54 -----LKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDD 100
+K I D++D+D+ E+ + + E + +KRKR + DD E+DD
Sbjct: 169 GLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD 220
Score = 53.5 bits (127), Expect = 2e-06
Identities = 47/176 (26%), Positives = 82/176 (46%), Gaps = 28/176 (15%)
Query: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDD 62
D E E+ E++ ++T +++ D ++ E ++ ++ DE G D+D
Sbjct: 71 DLFNCEITNLEDYRESIFELLQQIT--YLDGFDQEDNEAPDSEEEDDEDG-------DED 121
Query: 63 DEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGV-KVKRGQKYRRV 121
DE+E E + G G E++ ++ +D ED+D D LG + + G Y
Sbjct: 122 DEEEEENEAGPPEGYEEEEEEEEE------EDEDEDEDEDEAGSELGEGEEEVGLSYLMK 175
Query: 122 KKMSDDEDDDE-EEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDD 176
+++ D+EDDD+ E G+EE E+E G G++ A + EEEDD
Sbjct: 176 EEIQDEEDDDDYVEEGEEEEEEEE---------GGLRGEKRKRD--AEDDGEEEDD 220
Score = 48.5 bits (114), Expect = 6e-05
Identities = 35/123 (28%), Positives = 59/123 (47%), Gaps = 14/123 (11%)
Query: 135 YGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLK 194
+ +E++E EE +DG+ E+ +E E PPE EE++EE + +D D+D
Sbjct: 100 FDQEDNEAPDSEEEDDEDGD-EDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDE-- 156
Query: 195 KPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEYEDDEAEGEIRVR 254
+ L E +E G+ + E + E D++ EE E E++E EG +R
Sbjct: 157 -----------AGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 205
Query: 255 PKK 257
+K
Sbjct: 206 KRK 208
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 68.6 bits (166), Expect = 5e-11
Identities = 54/191 (28%), Positives = 91/191 (47%), Gaps = 18/191 (9%)
Query: 5 VESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDD- 63
++S EE E+E E + + + EE +++EEEE+++ DD D++ + NDD+D
Sbjct: 1029 LDSGGEEDEKESLSEEQE----STEEEEEAEEEEEEEDDDDDDSDDRDESE---NDDEDT 1081
Query: 64 --EDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRV 121
+ E+DEG + + K + TS + E +F+ E+ + V
Sbjct: 1082 ALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSES---SPSSSEDEEEV 1138
Query: 122 KKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDI 181
++E+++EEE EE A E+ QDGE EA AP AP + +EE DI
Sbjct: 1139 VAREEEEEEEEEEMVAEESMASAGPEDFEQDGE-----EAALAPGAPAVDSLGMEEEVDI 1193
Query: 182 DDFIVDDDGQP 192
+ V + +P
Sbjct: 1194 ETEAVAPEERP 1204
Score = 47.4 bits (111), Expect = 1e-04
Identities = 64/303 (21%), Positives = 110/303 (36%), Gaps = 78/303 (25%)
Query: 38 EEEEEENLDDQDEQGNLKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLE 97
+ +E + +Q L+ + D++++E E + D D+ ++ + K
Sbjct: 965 KRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPK--------- 1015
Query: 98 DDDFDLIEENLGVKVKRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEE 157
GV V+R R + + D G EE EKE+++EE E EE
Sbjct: 1016 -----------GVGVRR----RPARPLELDS-------GGEEDEKESLSEEQESTEEEEE 1053
Query: 158 GQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIF 217
+E E EE+++DD+ D D+ DD+ D AL EA E
Sbjct: 1054 AEEEEE------EEDDDDDDSDDRDESENDDE-----------------DTALSEASE-- 1088
Query: 218 GVDFDYDEFEKYNEYDEELEEEYEYEDDEAEGEIRVRPKKTTKKRVSRRSIFEM---YEP 274
++E + +++E + + + T+ S S FE P
Sbjct: 1089 -------------------KDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSP 1129
Query: 275 SELESSHLTDQDNEIRATDLPERFQLRSIPVKGAEDDELEEEADWIYRNAFATPTISLQE 334
S E E + E S+ G ED E + E + A A ++ ++E
Sbjct: 1130 SSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEE 1189
Query: 335 SCD 337
D
Sbjct: 1190 EVD 1192
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 66.6 bits (161), Expect = 2e-10
Identities = 73/278 (26%), Positives = 119/278 (42%), Gaps = 49/278 (17%)
Query: 1 MSDFVESEAEESEEEYNDEGEVVPRVTKKFVEEE----------DDDEEEEEENLDDQDE 50
M D E EE +E+ + EG + + EE DDDEEE+EE D++ E
Sbjct: 4737 MHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTE 4796
Query: 51 QGNLKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGV 110
+ G D++D + +D+ DSG+S D + +K + E DD
Sbjct: 4797 E---TGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEK--EEAEADD---------- 4841
Query: 111 KVKRGQKYRRVKKMSDDEDDDEEE----YGKEEHEKEAIAEEI-------------FQDG 153
GQ ++ + D+ D DE E +G +E E A ++ +D
Sbjct: 4842 ---GGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDT 4898
Query: 154 EGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEA 213
+ EEG+E E P+ E+ EE E++ + + D + P+ ++ P D A E
Sbjct: 4899 DNEEGEE--ENPLEIKEKPEEAGHEAE-ERGETETDQNESQSPQEPEEGPSEDDKAEGEE 4955
Query: 214 QEIFGV-DFDYDEFEKYNEYDEELEEEYEYEDDEAEGE 250
+ G D D D + E+ EE ++ E +D EA+ E
Sbjct: 4956 EMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEE 4993
Score = 58.2 bits (139), Expect = 7e-08
Identities = 42/175 (24%), Positives = 80/175 (45%), Gaps = 7/175 (4%)
Query: 10 EESEEEYNDEGEVVP-RVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDEDEGE 68
E+ +E DE EV P ++ V E + + ++ NLD +D+ G +D D +EGE
Sbjct: 4851 EQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGG------EDTDNEEGE 4904
Query: 69 EDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDE 128
E+ + + ++ GH+ +R + + E + + + + +DD+
Sbjct: 4905 EENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQ 4964
Query: 129 DDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDD 183
D D ++ +E E++ + E EEG E A +EEE+ E+SD ++
Sbjct: 4965 DGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEE 5019
Score = 53.9 bits (128), Expect = 1e-06
Identities = 77/347 (22%), Positives = 142/347 (40%), Gaps = 50/347 (14%)
Query: 3 DFVESEAEESEEEYND-------EGEVVPRVTKKFVEEE---DDDEEEEEENLDDQDEQG 52
+F+E A E E++D EGE + V+ + EE D ++ +E++ +D D +
Sbjct: 4659 EFMEDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKS 4718
Query: 53 NLKGFIN----------------------DDDDEDEGEEDEGSDSGDSEDDVGHKKRKRT 90
++KG N DD+ D D GD + K +R
Sbjct: 4719 DIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERL 4778
Query: 91 SFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIF 150
DD E+D+ + E+N + G + ++ D++ D K++ +++ E+
Sbjct: 4779 WGDDDEEEDEEE--EDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEK-- 4834
Query: 151 QDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAAL 210
++ E ++G + + + +E D +E+++D + G K P+ + L D L
Sbjct: 4835 EEAEADDGGQGED--KINEQIDERDYDENEVDPY----HGNQEKVPE-PEALDLPDDLNL 4887
Query: 211 QEAQEIFGVDFDYDEFEKYN--EYDEELEEEYEYEDDEAEGEIRVRPKKTTKKRVSRRSI 268
+ G D D +E E+ N E E+ EE ++ E E ++ ++ S
Sbjct: 4888 DSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSE 4947
Query: 269 FEMYEPSELESSHLTDQDNEIRATDLPERF---QLRSIPVKGAEDDE 312
+ E E + DQD + A PE Q +S+ K E DE
Sbjct: 4948 DDKAEGEEEMDTGADDQDGD--AAQHPEEHSEEQQQSVEEKDKEADE 4992
Score = 48.9 bits (115), Expect = 4e-05
Identities = 46/174 (26%), Positives = 78/174 (44%), Gaps = 10/174 (5%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQD-EQGNLKGFINDDDDE 64
+++ EE EEE E + P EE + E ++ E+ Q+ E+G +DD+
Sbjct: 4897 DTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGP------SEDDK 4950
Query: 65 DEGEEDEGSDSGDSEDDVG-HKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKK 123
EGEE+ + + D + D H + +E+ D + EE G Q + + ++
Sbjct: 4951 AEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEG-GENGPADQGF-QPQE 5008
Query: 124 MSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDE 177
+ ED D EE E E++ A E + +AME A PE+E+ +E
Sbjct: 5009 EEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEE 5062
Score = 40.0 bits (92), Expect = 0.020
Identities = 43/214 (20%), Positives = 89/214 (41%), Gaps = 27/214 (12%)
Query: 5 VESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEE--ENLDDQDE----QGNLKGFI 58
VE + +E++EE + G + EE +D + EE+ E L+ ++ Q ++
Sbjct: 4983 VEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQ 5042
Query: 59 NDD--------DDEDEGEEDEGSDSGDSEDDVGHKK----RKRTSFDDRLEDDDFDLIEE 106
N ++++G+E+ GS + D+ GH+ + + R F
Sbjct: 5043 NTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPG 5102
Query: 107 NLGVKVKRGQKYRRV-KKMSDDEDDDEEEYGKEEHEKEAI--AEEIFQDGEGEEGQEAME 163
+ G RV K++ + D E G + + + A+ +G + +A
Sbjct: 5103 QADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQT 5162
Query: 164 APMAPPEEEE------EDDEESDIDDFIVDDDGQ 191
+A E+++ +D EE +I+D ++D + Q
Sbjct: 5163 YDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQ 5196
Score = 34.7 bits (78), Expect = 0.83
Identities = 54/292 (18%), Positives = 105/292 (35%), Gaps = 42/292 (14%)
Query: 6 ESEAEESEEEYN-----DEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFIND 60
E + E EEE + +G+ + E++ EE+++E DE+G G +
Sbjct: 4947 EDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKE----ADEEGGENGPADQ 5002
Query: 61 DDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRR 120
E EE E SD+ + + +K + GV+ + +
Sbjct: 5003 GFQPQEEEEREDSDTEEQVPEALERKEHASC--------------GQTGVENMQNTQAME 5048
Query: 121 VKKMSDDEDDDEEEYGK--------EEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEE 172
+ + +++ +EE+G E HE IA+ Q + Q P E
Sbjct: 5049 LAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNER 5108
Query: 173 EEDDEESDIDDFI--VDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYN 230
D + + VD D + P + + A +++A + D ++
Sbjct: 5109 SMGDHNERVHKRLRTVDTDSHAEQGPAQQPQ------AQVEDADAFEHIKQGSDAYDAQT 5162
Query: 231 EYDEELEEEYEYED---DEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELES 279
E++ +D D+ E EI T ++ + + E +P E++S
Sbjct: 5163 YDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKS 5214
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 62.0 bits (149), Expect = 5e-09
Identities = 49/196 (25%), Positives = 91/196 (46%), Gaps = 24/196 (12%)
Query: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDD 62
+ VE + E E+ GE V + EE+D +E+EE DQ+E+ KG +D
Sbjct: 96 EIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEE----DQNEE---KGEAGKED 148
Query: 63 DEDEGEEDEGSDSGDSE--DDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRR 120
+++GEED D +E +D K+ + D + +D ++G+ +
Sbjct: 149 KDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGED----------GKEKGEDEKE 198
Query: 121 VKKMSDDEDDDEEEYGKEEHEKE-----AIAEEIFQDGEGEEGQEAMEAPMAPPEEEEED 175
+ + D E E GKE+ +K+ + E+ + +G+E + E +E+ ++
Sbjct: 199 EEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKE 258
Query: 176 DEESDIDDFIVDDDGQ 191
+EE +D I +DDG+
Sbjct: 259 EEEGKEEDEIKEDDGK 274
Score = 55.1 bits (131), Expect = 6e-07
Identities = 50/168 (29%), Positives = 85/168 (50%), Gaps = 24/168 (14%)
Query: 5 VESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDE 64
V++E E+ +E+ D+ E K +ED DE+ EE+ +D++ GN KG D ++
Sbjct: 123 VKNEEEDQKEDEEDQNE-----EKGEAGKEDKDEKGEEDGKEDKN--GNEKG--EDAKEK 173
Query: 65 DEGEEDE-----GSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLG--VKVKRGQK 117
++G++ E G D + +D ++ ++ + D + +D + ++ G VKVK +K
Sbjct: 174 EDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEK 233
Query: 118 YRRVKKMSDDEDDDEEEYG------KEEHEKEAIAEEIFQDGEGEEGQ 159
R K +DE +EEE G KEE E + E DG+ EE Q
Sbjct: 234 EREDGK--EDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEEPQ 279
Score = 35.0 bits (79), Expect = 0.63
Identities = 62/248 (25%), Positives = 96/248 (38%), Gaps = 51/248 (20%)
Query: 110 VKVKRGQKYRRVKKMSD--DEDDDEEEYGKEEHEKEAIAEEIF----QDGEG-------- 155
VK KR R++K SD +E+ D E ++EA+ EE + ++GE
Sbjct: 34 VKPKRTSSSRKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPAS 93
Query: 156 ----------------EEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLKKPKWR 199
E+G E EA A + EEED +E + D ++ G+ K+ K
Sbjct: 94 EKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQ--NEEKGEAGKEDKDE 151
Query: 200 KKLPGYTDAALQEAQEIFGVDFDYDEFEKYNE--------YDEELEEEYEYEDDEAEGEI 251
K G D + G D E K E E+ E+E E ED + G+
Sbjct: 152 K---GEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDG 208
Query: 252 RVR---PKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEIRATDLPERFQLRSIPVKGA 308
+ +K KK + E + E E + NE A E + +G
Sbjct: 209 KENEDGKEKGDKKEGKDVKVKE--DEKEREDGKEDEGGNEEEAGKEKEDLKEEE---EGK 263
Query: 309 EDDELEEE 316
E+DE++E+
Sbjct: 264 EEDEIKED 271
Score = 33.5 bits (75), Expect = 1.8
Identities = 24/89 (26%), Positives = 44/89 (49%), Gaps = 6/89 (6%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDD----EEEEEENLDDQDEQGNLKGFINDD 61
E E EE + + +G+ +K ++E D E+E+E +DE GN +
Sbjct: 194 EDEKEEEDRKETGDGKENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEA--GK 251
Query: 62 DDEDEGEEDEGSDSGDSEDDVGHKKRKRT 90
+ ED EE+EG + + ++D G K+ ++
Sbjct: 252 EKEDLKEEEEGKEEDEIKEDDGKKEEPQS 280
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 60.1 bits (144), Expect = 2e-08
Identities = 55/208 (26%), Positives = 93/208 (44%), Gaps = 38/208 (18%)
Query: 5 VESEAEESEEEYNDEGEVVPRVTKKFV--EEEDDDEEEEEENLDDQD------------- 49
++S++ EEE DE ++ +FV +E D+ EE+ + DD D
Sbjct: 1094 LDSDSNLDEEESEDEFKISDGSQDEFVVSDENPDESEEDPPSNDDSDTDFCSRRLRRHPS 1153
Query: 50 ---------EQGNLKGFINDDDDEDEGEED----EGSDSGDSEDDVGHKKRKRTSFDDR- 95
+ K +DDD+E+E EE+ E S D DD +R+R+ + +
Sbjct: 1154 RPMRQSRRLRRKTPKKKYSDDDEEEESEENSRDSESDFSDDFSDDFVETRRRRSRRNQKR 1213
Query: 96 ----LEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQ 151
ED + D +++L +RG++ RRV K + EE Y + E + +A+E +
Sbjct: 1214 QINYKEDSESDGSQKSL----RRGKEIRRVHKRRLSSSESEESYLSKNSEDDELAKE-SK 1268
Query: 152 DGEGEEGQEAMEAPMAPPEEEEEDDEES 179
+ G+ E A EEEEE+ + S
Sbjct: 1269 RSVRKRGRSTDEYSEADEEEEEEEGKPS 1296
Score = 45.8 bits (107), Expect = 4e-04
Identities = 53/233 (22%), Positives = 97/233 (41%), Gaps = 47/233 (20%)
Query: 8 EAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDE--QGNLKGFINDDDDED 65
+ E E + R ++ + + D D +EE +D+ + G+ F+ D++ D
Sbjct: 1068 DEERKENKRPQRAAAARRKKRRRLNDLDSDSNLDEEESEDEFKISDGSQDEFVVSDENPD 1127
Query: 66 EGEEDEGSDSGDSEDDVGHKK--------------------RKRTSFDDRLED------- 98
E EED S+ DS+ D ++ +K+ S DD E+
Sbjct: 1128 ESEEDPPSND-DSDTDFCSRRLRRHPSRPMRQSRRLRRKTPKKKYSDDDEEEESEENSRD 1186
Query: 99 ------DDF-DLIEENLGVKVKRGQKYRRVKKMSDDEDDDEEE---YGKE---EHEK--- 142
DDF D E + +R QK R++ D E D ++ GKE H++
Sbjct: 1187 SESDFSDDFSDDFVETRRRRSRRNQK-RQINYKEDSESDGSQKSLRRGKEIRRVHKRRLS 1245
Query: 143 EAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLKK 195
+ +EE + E+ + A E+ + + DE S+ D+ +++G+P +K
Sbjct: 1246 SSESEESYLSKNSEDDELAKESKRSVRKRGRSTDEYSEADEEEEEEEGKPSRK 1298
Score = 40.0 bits (92), Expect = 0.020
Identities = 46/197 (23%), Positives = 82/197 (41%), Gaps = 18/197 (9%)
Query: 7 SEAEESEEEYNDEGEVVPRVTKKFVEE---------EDDDEEEEEENLDDQDEQGNLKGF 57
SE+EES N E + + + +K+ V + E D+EEEEEE + ++
Sbjct: 1247 SESEESYLSKNSEDDELAKESKRSVRKRGRSTDEYSEADEEEEEEEGKPSRKRLHRIE-- 1304
Query: 58 INDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQK 117
++++ D D + DS+ V +++ T R+E D+ + EN+G KV
Sbjct: 1305 TDEEESCDNAHGDANQPARDSQPRVLPSEQESTKKPYRIESDEEEDF-ENVG-KVGSPLD 1362
Query: 118 YRRVKKMSDDEDDD----EEEYGKEEHEKEAIAEEIFQDGE-GEEGQEAMEAPMAPPEEE 172
Y V S + E GK + + + G + AP EEE
Sbjct: 1363 YSLVDLPSTNGQSPGKAIENLIGKPTEKSQTPKDNSTASASLASNGTSGGQEAGAPEEEE 1422
Query: 173 EEDDEESDIDDFIVDDD 189
+E +D+ D++ + +
Sbjct: 1423 DELLRVTDLVDYVCNSE 1439
Score = 36.6 bits (83), Expect = 0.22
Identities = 80/393 (20%), Positives = 143/393 (36%), Gaps = 85/393 (21%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQ-----DEQGNLKGFIND 60
E E E + G+ V +V + ++E+ + + E +NLD+ +E KG +
Sbjct: 644 EKEVVECQSTSTVGGQSVKKVDLETLKEDSEFTKVEMDNLDNAQTSGIEEPSETKGSMQK 703
Query: 61 DD------DEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEE-------- 106
E+E E ++ G K R S + D ++E
Sbjct: 704 SKFKYKLVPEEETTASENTEITSERQKEGIKLTIRISSRKKKPDSPPKVLEPENKQEKTE 763
Query: 107 ------NLGVKVKRGQKYRR----VKKMSDDEDDDEEEYGKEEHEKEAIA------EEIF 150
N+G ++R + R V ++ D + D + G++E E+E+ A +EI
Sbjct: 764 KEEEKTNVGRTLRRSPRISRPTAKVAEIRDQKADKKRGEGEDEVEEESTALQKTDKKEIL 823
Query: 151 QDGEGE---------------------------------EGQEAMEAPMAPPEEEEEDDE 177
+ E + EG + ++ A EEEE++ E
Sbjct: 824 KKSEKDTNSKVSKVKPKGKVRWTGSRTRGRWKYSSNDESEGSGSEKSSAASEEEEEKESE 883
Query: 178 ESDIDDFIVDDDGQPLKK---PKWRKKL-------PGYTDAALQEAQEIFGVDFDYDEFE 227
E+ I+ DD +P KK P + + GY A L+ I +
Sbjct: 884 EA-----ILADDDEPCKKCGLPNHPELILLCDSCDSGYHTACLRPPLMIIPDGEWFCPPC 938
Query: 228 KYNEYDEELEEEYEYEDDEAEGEIRV--RPKKTTKKRVSRRSIFEMYEPSELESSHLTDQ 285
++ E+LEE+ + D + + R R ++ +S +I EP E +
Sbjct: 939 QHKLLCEKLEEQLQDLDVALKKKERAERRKERLVYVGISIENIIPPQEPDFSEDQEEKKK 998
Query: 286 DNEIRATDLPERFQLRSIPVKGAEDDELEEEAD 318
D++ +L ER R+ DE +E D
Sbjct: 999 DSKKSKANLLERRSTRTRKCISYRFDEFDEAID 1031
Score = 35.4 bits (80), Expect = 0.48
Identities = 29/112 (25%), Positives = 57/112 (50%), Gaps = 5/112 (4%)
Query: 400 DEKWTQLRIRKENLTRLFEKMQAYQYEQISADPDKPLADGIRALDTTDMERLKDVQSM-- 457
D K ++ + + TR K +Y++++ D+ + D I+ D + R KD+ ++
Sbjct: 999 DSKKSKANLLERRSTRT-RKCISYRFDEFDEAIDEAIEDDIKEADGGGVGRGKDISTITG 1057
Query: 458 DELKDVYNHFLLYYGRDIPKMQNAAKASRKKLKRVRE-EGDEEGEGDEAEDE 508
KD+ + L ++ + Q AA A RKK +R+ + + D + +E+EDE
Sbjct: 1058 HRGKDI-STILDEERKENKRPQRAAAARRKKRRRLNDLDSDSNLDEEESEDE 1108
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 60.1 bits (144), Expect = 2e-08
Identities = 67/320 (20%), Positives = 142/320 (44%), Gaps = 32/320 (10%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDD--DEEEEEENLDDQDEQGNLKGFINDDDD 63
E + EE E+ E E R ++ +EE+ EE E+ +++ Q + ++
Sbjct: 912 ELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEE 971
Query: 64 EDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKK 123
+ GEE E + E K+ ++ L+ ++ L+ E + +R Q++ R +
Sbjct: 972 QLLGEEPEKRRRQERE--------KKYREEEELQQEEEQLLREER--EKRRRQEWERQYR 1021
Query: 124 MSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEE---EEEDDEESD 180
D+ +EE+ +EE EK + E Q E EE Q+ E + E +E + +
Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR 1081
Query: 181 IDDFIVDDDGQPLK-KPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEE 239
++ + ++ Q L+ +P+ R++ + +E +E+ + E+ +ELE +
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQE--RERQCREEEELQQEEEQLLREEREKRRRQELERQ 1139
Query: 240 YEYEDD---EAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEIRATDLPE 296
Y E++ E E +R P+K ++ + R+ + E + E L ++ E R +
Sbjct: 1140 YREEEEVQQEEEQLLREEPEKRRRQELERQ--YREEEELQQEEEQLLREEQEKRRQERER 1197
Query: 297 RFQLRSIPVKGAEDDELEEE 316
+++ E++EL+ +
Sbjct: 1198 QYR---------EEEELQRQ 1208
Score = 47.4 bits (111), Expect = 1e-04
Identities = 69/346 (19%), Positives = 144/346 (41%), Gaps = 55/346 (15%)
Query: 12 SEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDEDEG--EE 69
+EE E +P +K E E+E +++EQ + +E++G E+
Sbjct: 800 AEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQED 859
Query: 70 DEGSDSGDSEDD--------VGHKKRKRTSF------------DDRLEDDDFDLIEENLG 109
E S + D K+R+ T + L++++ +L E
Sbjct: 860 QERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREERE 919
Query: 110 VKVKRGQ--KYRRVKKMSDDED----DDEEEYGKEEHEKEAIAEEIFQD------GEGEE 157
+ ++ Q +YR +++ +E+ ++ E+ ++E E++ ++ Q GE E
Sbjct: 920 KRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPE 979
Query: 158 GQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIF 217
+ E EEEE EE ++ ++ + ++ +W ++ D QE +++
Sbjct: 980 KRRRQEREKKYREEEELQQEEEQ----LLREEREKRRRQEWERQY-RKKDELQQEEEQLL 1034
Query: 218 GVDFDYDEF-EKYNEYDEELEEEYEYEDDEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSE 276
+ + E+ +Y E EEE + E+++ GE ++ T++R + E +
Sbjct: 1035 REEREKRRLQERERQYRE--EEELQQEEEQLLGE-----ERETRRRQELERQYRKEEELQ 1087
Query: 277 LESSHLTDQDNEIRATDLPERFQLRSIPVKGAEDDELEEEADWIYR 322
E L ++ E R ER Q R E++EL++E + + R
Sbjct: 1088 QEEEQLLREEPEKRRRQERER-QCR-------EEEELQQEEEQLLR 1125
Score = 44.7 bits (104), Expect = 8e-04
Identities = 146/790 (18%), Positives = 302/790 (38%), Gaps = 106/790 (13%)
Query: 5 VESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDE 64
+E + + EE +E +++ +K +E + + EEE L ++EQ + ++ ++
Sbjct: 1076 LERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQ-----LLREEREK 1130
Query: 65 DEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKM 124
+E E ++ ++ ++ ++ L+ E + +R Q+ R +
Sbjct: 1131 RRRQELE----------------RQYREEEEVQQEEEQLLREE--PEKRRRQELERQYRE 1172
Query: 125 SDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEED-------DE 177
++ +EE+ +EE EK E Q E EE Q E++ D ++
Sbjct: 1173 EEELQQEEEQLLREEQEKRR-QERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEK 1231
Query: 178 ESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYD---EFEKYNEYDE 234
E+ + D V G+ ++ + + + Q+ Q + G + D E ++ + D
Sbjct: 1232 ENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDR 1291
Query: 235 ELEEEYEYEDDEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEIRATDL 294
EE + E +E + R K +K++ R E E + ++ +
Sbjct: 1292 HFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQ 1351
Query: 295 PERFQLRSIPVKGAEDDELEEEADWIYRNAFATPTISLQESCDYLDRGQPASSFSRKGPS 354
P R Q R + ++EL + ++ +L+ Q R+
Sbjct: 1352 PLRRQERD---RKFREEELRHQ----------------EQGRKFLEEEQRLRRQERE--- 1389
Query: 355 TIQKIKEALGFMRNQHFEVPFIAFYRKEYVEPELHINDLWRVWQWDEKWTQLRIRKENLT 414
+K + +R Q E +++ E E ++ R ++ E+ Q+R R+E
Sbjct: 1390 --RKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR-RQERER 1446
Query: 415 RLFEKMQAYQYEQISADPDKPLADGIRALDTTDMERLKDVQSMDELKDVYNHFLLYYGRD 474
+ E+ Q + E+ + ++ Q + E ++ H +
Sbjct: 1447 KFLEEEQQLRQER-------------------HRKFREEEQLLQEREEQQLHRQERDRKF 1487
Query: 475 IPKMQNAAKASRKKLKRVREEGDEEGEGDEAEDEEQRGPELKQAS--RRDMYTICQSAG- 531
+ + Q + R + R +E +E E E+E+Q + +Q + + Q G
Sbjct: 1488 LEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQ 1547
Query: 532 --LDGLAKKFGLTPEQFGENLRDSYQRHETE-QFPAEPLELAKDYVCSQFPTPEAVLEGA 588
+KF + E R E + +F E ++ + +F E L
Sbjct: 1548 QRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQ 1607
Query: 589 RYMVALQIAREPLVRQVLRQTFQERAKLNITPTKKGRKDVDEAHYAYSFKYLKNKPVKEL 648
L+ R+ R+ Q QER + + ++ RK ++E + + + ++L
Sbjct: 1608 EGQQQLRQERDRKFRED-EQLLQEREEQQLHRQERDRKFLEEEP-----QLRRQEREQQL 1661
Query: 649 RDDQFLKICLAEDEGLLTTDISIDLKGVEGYGNDQTYFEEIKQFYYRDEFSHQVQEWNRQ 708
R D+ K E+E LL L+ E D+ + EE +Q ++ +QE +
Sbjct: 1662 RHDRDRK--FREEEQLLQEGEEQQLRRQE---RDRKFREEEQQLRRQERERKFLQEEQQL 1716
Query: 709 RTMAIERALQQFLYVQMAKELKNKLLAEAKEYVIKACSRKLYNWLRVAPYRPDQQV---E 765
R +ER ++ Q+ +E + + L + Y RK+ ++ P R +QQ+ E
Sbjct: 1717 RRQELERKFRE--EEQLRQETEQEQLRRQERY------RKILEEEQLRPEREEQQLRRQE 1768
Query: 766 EDDDFMDENQ 775
D F +E Q
Sbjct: 1769 RDRKFREEEQ 1778
Score = 43.9 bits (102), Expect = 0.001
Identities = 142/782 (18%), Positives = 309/782 (39%), Gaps = 102/782 (13%)
Query: 10 EESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDEDEGEE 69
EE E+E+ V+ + EEE EEE + + Q+E+ L+ + + EE
Sbjct: 240 EEEEKEWRKRETVLRK------EEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEE 293
Query: 70 DEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDED 129
++ E + K+ ++R E + E + + Q+ RR +++ +++
Sbjct: 294 EQQQQRLRREQQLRRKQE-----EERREQQE----ERREQQERREQQEERREQQLRREQE 344
Query: 130 DDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDD 189
+ E+ + E E+E +++ ++ E E ++ + E++ E+
Sbjct: 345 ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQ----------- 393
Query: 190 GQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEYEDDEAEG 249
Q ++ + R++ + L+ Q++ +++L E E E E +
Sbjct: 394 -QLRREQQLRREQQLRREQQLRREQQL--------------RREQQLRREQEEERHEQKH 438
Query: 250 EIRVRPKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEIRATDLPERFQLRSIPVKGAE 309
E R ++ +++ RR + E +E H ++ + D E + R + ++ E
Sbjct: 439 EQERREQRLKREQEERRDWLKREEETE---RHEQERRKQQLKRDQEEERRERWLKLEEEE 495
Query: 310 DDELEEEADWIYRNAFATPTISLQESCDYLDRGQPASSFSRKGPSTIQKIKEALGFMRNQ 369
E +E + R +E + + Q ++ + Q+++ R Q
Sbjct: 496 RREQQERREQQLRR-------EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ 548
Query: 370 HFEVPFIAFYRKEYVEPELHINDLWR---VWQWDEKWTQLRIRKENLTRLFEKMQAYQYE 426
+ +E E L R + + +E+ Q R+++E RL ++++ + E
Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVE 608
Query: 427 QISADPDKPLADGIRALDTTDMERLKDVQSMDELKDVYNHFLLYYGRDIPKMQNAAKASR 486
++ + + + + + ER + + +E ++ L ++ + + +
Sbjct: 609 RLEQEERR---EQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEE 665
Query: 487 KKL-KRVREEGDEEGEGDEAEDEEQRGPELKQASRRDMYTICQSAGLDGLAKKFGLTP-E 544
++L +R++ E +EE E +EEQ + SR + + D K P +
Sbjct: 666 ERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRK 725
Query: 545 QFGENLRD-------------SYQRHETEQFPAEPLELAKDYVCSQFPTPEAVLEGARYM 591
Q G+ R +Q E + E +D+ Q+ E G + +
Sbjct: 726 QEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTW-QWQAEEKSERGRQRL 784
Query: 592 VALQIAREPLVRQVLRQTFQERAKLNITPTKKGRKDVDEAHYAYSFKYLKNKPVKELRDD 651
A RE RQ+ + Q+R ++ + E + + + KEL
Sbjct: 785 SARPPLREQRERQLRAEERQQRE----------QRFLPEEEEKEQRRRQRREREKEL--- 831
Query: 652 QFLKICLAEDEGLLTTDISIDLKGVE-GYGNDQTYFEEIKQFYYRDE-FSHQVQEWNRQR 709
QFL+ E+E L + + L+ E G DQ Q RD+ + Q++E ++R
Sbjct: 832 QFLE----EEEQLQRRERAQQLQEEEDGLQEDQE--RRRSQEQRRDQKWRWQLEEERKRR 885
Query: 710 --TMAIERALQQFLYVQMAKELKNKLLAEAKEYVIKACSRKLYNWLRVAPYRPDQQVEED 767
T+ + ALQ+ Q+ KE +LL E +E + + K + YR ++Q++++
Sbjct: 886 RHTLYAKPALQE----QLRKE--QQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQE 939
Query: 768 DD 769
++
Sbjct: 940 EE 941
Score = 42.7 bits (99), Expect = 0.003
Identities = 81/454 (17%), Positives = 183/454 (40%), Gaps = 68/454 (14%)
Query: 10 EESEEEYNDEGEVVPRVT-KKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDD----- 63
+E E ++ +E + + + +KF EEE +E EE+ L Q+ + F+ ++
Sbjct: 1442 QERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERD---RKFLEEEQQLRRQE 1498
Query: 64 ------EDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQK 117
E E E E+ H+++++ F E+ E + R +K
Sbjct: 1499 RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKF--LQEEQQLRRQERGQQRRQDRDRK 1556
Query: 118 YRRVKKMSDDEDD--------------DEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAME 163
+R +++ + ++ +E++ ++E E++ + +E Q +EGQ+ +
Sbjct: 1557 FREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDE--QQLRRQEGQQQL- 1613
Query: 164 APMAPPEEEEEDDEESDIDDFIVDDDGQPL-KKPKWRKKLPGYTDAALQEAQEIFGVDFD 222
+E D + + + + + + Q L ++ + RK L QE ++
Sbjct: 1614 -------RQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQ----QLR 1662
Query: 223 YDEFEKYNEYDEELEEEYEYEDDEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELESSHL 282
+D K+ E ++ L+E E + E + + R ++ +R R F
Sbjct: 1663 HDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKF------------- 1709
Query: 283 TDQDNEIRATDLPERFQLRSIPVKGAEDDELEEEADWIYRNAFATPTISLQESCDYLDRG 342
++ ++R +L +F+ + E ++L + YR + + L R
Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQER--YRKILEEEQLRPEREEQQLRRQ 1767
Query: 343 QPASSFSRKGPSTIQKIKEALGFMRNQHFEVPF--IAFYRKEYVEPELHINDLWRVWQWD 400
+ F + ++ ++ L R+Q + F R+E E +L ++W+
Sbjct: 1768 ERDRKFREEEQLRQEREEQQL---RSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWE 1824
Query: 401 EKWTQLRIRKENLTRLFEKMQAYQYEQISADPDK 434
E+ QL +++ L + E+ + Y+ E+ A +K
Sbjct: 1825 EEQLQLEEQEQRLRQ--ERDRQYRAEEQFATQEK 1856
Score = 42.0 bits (97), Expect = 0.005
Identities = 62/321 (19%), Positives = 134/321 (41%), Gaps = 25/321 (7%)
Query: 4 FVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDD 63
F+E E + +E E ++ +KF EEE +E EE+ L Q+ + ++
Sbjct: 1645 FLEEEPQLRRQER--EQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFR------EE 1696
Query: 64 EDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKK 123
E + E E+ ++ +R + + +++ L +E +++R ++YR++ +
Sbjct: 1697 EQQLRRQERERKFLQEE----QQLRRQELERKFREEE-QLRQETEQEQLRRQERYRKILE 1751
Query: 124 MSD-DEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDID 182
+ +E++ ++E +++ EE + E+ + E+ EEE+ E +
Sbjct: 1752 EEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQ 1811
Query: 183 DFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEY 242
DG K +W ++ + + QE D Y E++ ++ EE E
Sbjct: 1812 LRPQQRDG----KYRWEEEQLQLEEQEQRLRQE---RDRQYRAEEQFATQEKSRREEQEL 1864
Query: 243 EDDEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEIRATDL-PERFQLR 301
+E + + R +K ++ + R+ + E + + Q+ + L P Q
Sbjct: 1865 WQEEEQKRRQERERKLREEHIRRQ---QKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQFA 1921
Query: 302 SIPVKGAEDDELEEEADWIYR 322
S+PV+ + E +E YR
Sbjct: 1922 SVPVRSSPLYEYIQEQRSQYR 1942
Score = 37.7 bits (86), Expect = 0.097
Identities = 58/322 (18%), Positives = 130/322 (40%), Gaps = 18/322 (5%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDED 65
E E EEE + + ++ EEE +++EE ++ EQ + +
Sbjct: 285 ELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERR--EQQLRRE 342
Query: 66 EGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMS 125
+ E E + E++ ++ +R ++R E + +++R Q+ RR +++
Sbjct: 343 QEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402
Query: 126 DDEDDDEEEYGKEE----HEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEED--DEES 179
++ E+ + E E++ E+ + E + QE E + +EE D E
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREE 462
Query: 180 DIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEE 239
+ + + Q LK+ + ++ + +E +E + E + E +E E+
Sbjct: 463 ETERHEQERRKQQLKRDQEEERRERWLKLEEEERRE----QQERREQQLRREQEERREQR 518
Query: 240 YEYEDDEAEGEIRVRPKKTTKKRVS--RRSIFEMYEPSELE----SSHLTDQDNEIRATD 293
+ +++E + R+R ++ ++ R + + E LE L + E R
Sbjct: 519 LKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQL 578
Query: 294 LPERFQLRSIPVKGAEDDELEE 315
L + R +K +++ LE+
Sbjct: 579 LKREEERRQQRLKREQEERLEQ 600
Score = 36.6 bits (83), Expect = 0.22
Identities = 66/321 (20%), Positives = 126/321 (39%), Gaps = 29/321 (9%)
Query: 28 KKFVEEEDDDEEEEEENLDDQDEQGNLK---GFINDDDDEDEGEEDEGSDSGDSEDDVGH 84
+KF EEE +E EE+ L Q+ + + + E + EDE
Sbjct: 1555 RKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLR 1614
Query: 85 KKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMSDD--EDDDEEEYGKEEHEK 142
++R DR +D L++E ++ R ++ R+ + + E++ + K
Sbjct: 1615 QER------DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRK 1668
Query: 143 EAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLKKPKWRKKL 202
E++ Q+GE E+ E EEE++ + F+ ++ Q L++ + +K
Sbjct: 1669 FREEEQLLQEGE-EQQLRRQERDRKFREEEQQLRRQERERKFLQEE--QQLRRQELERKF 1725
Query: 203 PGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEY---EYEDDEAEGEIRVRPKKTT 259
+ QE Y + + + E EE+ + D + E ++R ++
Sbjct: 1726 REEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREE 1785
Query: 260 KKRVSRRSIFEMYEPSEL----ESSHLTDQDNEIRATDLPERFQLRSIPVKGAEDDELEE 315
++ S+ S + E +L E L Q + + E+ QL ++ L +
Sbjct: 1786 QQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEE------QEQRLRQ 1839
Query: 316 EADWIYR--NAFATPTISLQE 334
E D YR FAT S +E
Sbjct: 1840 ERDRQYRAEEQFATQEKSRRE 1860
Score = 35.0 bits (79), Expect = 0.63
Identities = 45/263 (17%), Positives = 108/263 (41%), Gaps = 14/263 (5%)
Query: 33 EEDDDEEEEEENLDDQDEQGNLKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSF 92
+E+D E + ++E G + E E E EG + + ++ + + R+R
Sbjct: 115 QEEDQRRFEPRDRQLEEEPGQRR---RQKRQEQERELAEGEEQSEKQERLEQRDRQRRDE 171
Query: 93 DDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQD 152
+ + ++ EE +R ++ +++ + + EE+ EE + E+ +
Sbjct: 172 ELWRQRQEWQEREE------RRAEE----EQLQSCKGHETEEFPDEEQLRRRELLELRRK 221
Query: 153 GEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQ- 211
G E+ Q+ E +EEEE + +++ ++P+ +++L + +
Sbjct: 222 GREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL 281
Query: 212 EAQEIFGVDFDYDEFEKYNEYDEELEEEYEYEDDEAEGEIRVRPKKTTKKRVSRRSIFEM 271
E QE+ + ++ ++ +++L + E E E + E R + ++ ++ R
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341
Query: 272 YEPSELESSHLTDQDNEIRATDL 294
+ E +Q+ E R L
Sbjct: 342 EQEERREQQLRREQEEERREQQL 364
Score = 32.3 bits (72), Expect = 4.1
Identities = 43/252 (17%), Positives = 118/252 (46%), Gaps = 15/252 (5%)
Query: 72 GSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIE-ENLGVKVKRGQKYR-----RVKKMS 125
G +G E+ K + DR +++D E + ++ + GQ+ R + ++++
Sbjct: 90 GQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELA 149
Query: 126 DDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFI 185
+ E+ E++ E+ +++ EE+++ + +E QE E EE+ + + + ++F
Sbjct: 150 EGEEQSEKQERLEQRDRQRRDEELWR--QRQEWQEREE--RRAEEEQLQSCKGHETEEF- 204
Query: 186 VDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEEL-EEEYEYED 244
D + L++ + + + Q+ +E F +E +++ + + L +EE + ++
Sbjct: 205 --PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQE 262
Query: 245 DEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEIRATDLPERFQLRSIP 304
+E + + ++ ++ +++ R+ + + E + L ++ ++R ER + +
Sbjct: 263 EEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLR-REQQLRRKQEEERREQQEER 321
Query: 305 VKGAEDDELEEE 316
+ E E +EE
Sbjct: 322 REQQERREQQEE 333
>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
Length = 1312
Score = 59.7 bits (143), Expect = 2e-08
Identities = 73/340 (21%), Positives = 139/340 (40%), Gaps = 77/340 (22%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDED 65
E+E E E + +E ++PR K +DE E +EN+ + G+ K +
Sbjct: 431 ENETEIKEIKMEEERNIIPREEKPI-----EDEIERKENI--KPSLGSKKNLLESIPTHS 483
Query: 66 EGEEDEGSDSGDSEDDVGHKKRK-RTSFDDRLEDDDFDLIEENLGVKVK-RGQKYRRVKK 123
D E +V KK + + DD+ DDD ++E+L +KV+ +K + +
Sbjct: 484 -----------DQEKEVNIKKPEDNENLDDK--DDDTTRVDESLNIKVEAEEEKAKSGDE 530
Query: 124 MSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDD 183
+ +ED+D+EE +EE E+E EE+E+DD+ ++ ++
Sbjct: 531 TNKEEDEDDEEAEEEEEEEE-------------------------EEEDEDDDDNNEEEE 565
Query: 184 FIVDDDGQPLKKPKWRKKLPGYTDAALQEAQ----------EIFGVDFDYDEFEKYN--- 230
F G ++ R K +A+++++ G + YDE+ K +
Sbjct: 566 FECYPPGMKVQVRYGRGKNQKMYEASIKDSDVEGGEVLYLVHYCGWNVRYDEWIKADKIV 625
Query: 231 ----------EYDEELEEEYEYEDDEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELESS 280
++ ++++ + + E D+ E + PK +R+S+ P +
Sbjct: 626 RPADKNVPKIKHRKKIKNKLDKEKDKDE---KYSPKNCKLRRLSKPPFQTNPSPEMVSKL 682
Query: 281 HLTDQDN----EIRATDLPERFQLRSIPVKGAEDDELEEE 316
LTD N I++ ++ AED E E+E
Sbjct: 683 DLTDAKNSDTAHIKSIEITSILNGLQASESSAEDSEQEDE 722
Score = 36.2 bits (82), Expect = 0.28
Identities = 23/85 (27%), Positives = 43/85 (50%), Gaps = 16/85 (18%)
Query: 5 VESEAEESEEEYNDEGEVVPRVTKKF---VEEEDD-----DEEEEEENLDDQDEQGNLKG 56
V + E E +D+ + RV + VE E++ DE +EE+ DD++ +
Sbjct: 489 VNIKKPEDNENLDDKDDDTTRVDESLNIKVEAEEEKAKSGDETNKEEDEDDEEAE----- 543
Query: 57 FINDDDDEDEGEEDEGSDSGDSEDD 81
++++E+E EEDE D + E++
Sbjct: 544 ---EEEEEEEEEEDEDDDDNNEEEE 565
Score = 34.7 bits (78), Expect = 0.83
Identities = 33/179 (18%), Positives = 68/179 (37%), Gaps = 26/179 (14%)
Query: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDD 62
D + + +E N + E K E +++E++EE ++++E+ + DDD
Sbjct: 501 DDKDDDTTRVDESLNIKVEAEEEKAKSGDETNKEEDEDDEEAEEEEEEEEEEED--EDDD 558
Query: 63 DEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDF--------------------- 101
D +E EE E G + + + ++ ++D D
Sbjct: 559 DNNEEEEFECYPPGMKVQVRYGRGKNQKMYEASIKDSDVEGGEVLYLVHYCGWNVRYDEW 618
Query: 102 ---DLIEENLGVKVKRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEE 157
D I V + + +++K D E D +E+Y + + +++ FQ E
Sbjct: 619 IKADKIVRPADKNVPKIKHRKKIKNKLDKEKDKDEKYSPKNCKLRRLSKPPFQTNPSPE 677
Score = 31.6 bits (70), Expect = 7.0
Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 11/51 (21%)
Query: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGN 53
D SEAEE EEE +DE E +ED+ EEEEE +E+ N
Sbjct: 272 DSSSSEAEEEEEEEDDEKE-----------KEDNSSEEEEEIEPFPEEREN 311
>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member A [Homo sapiens]
Length = 249
Score = 59.3 bits (142), Expect = 3e-08
Identities = 39/101 (38%), Positives = 58/101 (57%), Gaps = 26/101 (25%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLD-----DQDEQGNLKGFIND 60
+ E +E EEEY+++ +VV +EED+DEEEE E D ++DE+G G ++D
Sbjct: 169 DEEEDEDEEEYDEDAQVVE-------DEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDD 221
Query: 61 DDDEDE-GEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDD 100
++DE+E GEE+ G +KRKR +D EDDD
Sbjct: 222 EEDEEELGEEERG------------QKRKREP-EDEGEDDD 249
Score = 53.5 bits (127), Expect = 2e-06
Identities = 36/103 (34%), Positives = 56/103 (54%), Gaps = 11/103 (10%)
Query: 32 EEEDDDEEEEEENLDDQDEQGNLKGFIND----DDDEDEGEEDEGSDSGDSEDDVGHKKR 87
E D D E E LDD++E + + + D +D+EDE EE+E G+ ED G ++
Sbjct: 154 EAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEE----GEEEDVSGEEEE 209
Query: 88 KRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDEDD 130
++D DD+ D EE LG + +RGQK +R + ++DD
Sbjct: 210 DEEGYNDGEVDDEED--EEELG-EEERGQKRKREPEDEGEDDD 249
Score = 37.7 bits (86), Expect = 0.097
Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 6/78 (7%)
Query: 126 DDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFI 185
++ED+DEEEY E + E+ + E EEG+E E EE+EE + ++DD
Sbjct: 170 EEEDEDEEEY----DEDAQVVEDEEDEDEEEEGEE--EDVSGEEEEDEEGYNDGEVDDEE 223
Query: 186 VDDDGQPLKKPKWRKKLP 203
+++ ++ + RK+ P
Sbjct: 224 DEEELGEEERGQKRKREP 241
Score = 34.3 bits (77), Expect = 1.1
Identities = 30/127 (23%), Positives = 54/127 (42%), Gaps = 25/127 (19%)
Query: 118 YRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDE 177
Y R K + D D + G ++ E++ EE +D + E +E E+EEE+ E
Sbjct: 148 YDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEE--------DEDEEEEGE 199
Query: 178 ESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELE 237
E D+ +D+ GY D + + ++ + + E E+ + E E
Sbjct: 200 EEDVSGEEEEDE-------------EGYNDGEVDDEED----EEELGEEERGQKRKREPE 242
Query: 238 EEYEYED 244
+E E +D
Sbjct: 243 DEGEDDD 249
Score = 32.3 bits (72), Expect = 4.1
Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 26/119 (21%)
Query: 136 GKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLKK 195
G + +KEA D + E E ++ EEE+ED+EE D D +V+D+ ++
Sbjct: 147 GYDRDDKEA------PDSDAEGYVEGLD-----DEEEDEDEEEYDEDAQVVEDEEDEDEE 195
Query: 196 PKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEYEDDEAEGEIRVR 254
+ E +++ G + + DE E YN+ + + EE+ E +E G+ R R
Sbjct: 196 EEG-------------EEEDVSGEE-EEDE-EGYNDGEVDDEEDEEELGEEERGQKRKR 239
Score = 32.0 bits (71), Expect = 5.3
Identities = 34/141 (24%), Positives = 59/141 (41%), Gaps = 11/141 (7%)
Query: 384 VEPELHINDLWRVWQWDEKWTQLRIRKENLTRLFEKM---QAYQYEQISADPDKPLADGI 440
+EP + +L + ++ + T L +EN+ +L ++ Y + A PD +
Sbjct: 106 IEPLKKLENLKSLDLFNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEA-PDSDAEGYV 164
Query: 441 RALDTTDMERLKDVQSMDELKDVYNHFLLYYGRDIPKMQNAAKASRKKLKRVREEGDEEG 500
LD D E +D + DE V D + + + + EEG +G
Sbjct: 165 EGLD--DEEEDEDEEEYDEDAQVVED-----EEDEDEEEEGEEEDVSGEEEEDEEGYNDG 217
Query: 501 EGDEAEDEEQRGPELKQASRR 521
E D+ EDEE+ G E + R+
Sbjct: 218 EVDDEEDEEELGEEERGQKRK 238
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 59.3 bits (142), Expect = 3e-08
Identities = 72/318 (22%), Positives = 134/318 (42%), Gaps = 64/318 (20%)
Query: 10 EESEEEYN--DEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDE--- 64
E +EEE+ D+ + + K+ ++ D +E E++++ + + ++ + DDD+
Sbjct: 85 ENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFN 144
Query: 65 -----------------DEGEEDE--------------GSDSGDSEDDV-----GHKKRK 88
D EEDE +SGD D+ G KK +
Sbjct: 145 KLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQ 204
Query: 89 RTSFDDRLE--DDDFDLIEENLGVKVKRGQKYRRVKKMSDDE--------DDDEEEYGKE 138
+ +E ++D D + V K+ +K R +K D+E + +E E GK+
Sbjct: 205 KNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKK 264
Query: 139 EHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLKKPKW 198
+ K+ ++ F++ E + + ++ + P EE+ + + DD D + KK K
Sbjct: 265 DQSKQKESQRKFEE-ETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKG 323
Query: 199 RK------KLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYD-----EELEEEYEYEDDEA 247
K K G + A ++ QE + +E +K E + EELE + + E++
Sbjct: 324 EKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRK-EEERL 382
Query: 248 EGEIRVRPKKTTKKRVSR 265
E E R R K+ K+R R
Sbjct: 383 EQEKRERKKQKEKERKER 400
Score = 53.9 bits (128), Expect = 1e-06
Identities = 41/119 (34%), Positives = 64/119 (53%), Gaps = 8/119 (6%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEE--EENLDDQDEQGNLKGFINDDDD 63
E+ A + E E + +V V + EEE+++EEEE EE+ ++++E+G +G ++ D+
Sbjct: 507 EAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEG--SEGDE 564
Query: 64 EDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVK 122
EDE DE DSG + D K K S D + DD EE K KR + RR++
Sbjct: 565 EDEKVSDE-KDSGKTLD---KKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLE 619
Score = 47.4 bits (111), Expect = 1e-04
Identities = 75/323 (23%), Positives = 128/323 (39%), Gaps = 66/323 (20%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTK---KFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDD 62
E E +E E++ V + + K EEE+ + EEEE + +E
Sbjct: 324 EKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEEL----------- 372
Query: 63 DEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVK 122
E + +E+E + E KK+K +RL+ + L + + + + ++
Sbjct: 373 -EAKRKEEERLEQEKRE----RKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQ 427
Query: 123 KMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAP-------PEEEE-- 173
+ + K ++ ++I Q E +E E+ME A PE+EE
Sbjct: 428 AQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETP 487
Query: 174 ---EDDEESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYN 230
E +EE D +D +DD W A+ +E +++ G + K N
Sbjct: 488 PPVEPEEEEDTEDAGLDD---------WEAM------ASDEETEKVEGNKVHIEV--KEN 530
Query: 231 EYDEELEEEYEYEDDEAEGE----------------IRVRPKKTTKKRVSRRSIFEMYEP 274
+EE EEE E ED+E+E E +V +K + K + ++ EM
Sbjct: 531 PEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSD 590
Query: 275 SELESSHLTDQDNEIRATDLPER 297
SE +S D+ E RA D +R
Sbjct: 591 SEYDSD--DDRTKEERAYDKAKR 611
Score = 35.0 bits (79), Expect = 0.63
Identities = 77/354 (21%), Positives = 144/354 (40%), Gaps = 58/354 (16%)
Query: 60 DDDDEDE-GEEDEGSDSGDSEDDVGHK--KRKRTSFDDRLEDDDFDLIEENLGVKVKRGQ 116
DD D D E EG+ + ++ K K+K D EDD +EE L ++ + +
Sbjct: 15 DDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEE-LSLEAQGIK 73
Query: 117 KYRRVKKMSDDEDDDEEEYGKEEHEK-EAIAEEIFQDGEGE--EGQEAMEAPMAPPEEEE 173
R + E+++EE K++ +K + ++ F D + E E +++ A P+ E
Sbjct: 74 ADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEM 133
Query: 174 EDDEESDIDDFIVDDDGQPLKKPKWRKKLPGYTD-----AALQEAQEIFGVDFDYDEFEK 228
+ D DDF K K KK G + ++E I DE ++
Sbjct: 134 YSGSDDD-DDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDE 192
Query: 229 YNEYDEELEE----------EYEYEDDEAEGEIR-VRPKKTTKKRVSRR-------SIFE 270
+ + + ++ E EDD+A +I+ V KK KK R+ + +
Sbjct: 193 FLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRK 252
Query: 271 MYEPSELESSHLTDQDNEIRATDLPERFQLRSIPVKGAEDDEL----EEEADWIYRNAFA 326
+ E ELE T + ++ + + +F+ ++ K D + EE+A+
Sbjct: 253 LKEKEELE----TGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAE-------- 300
Query: 327 TPTIS---------LQESCDYLDRGQPASSFSRKGPS--TIQKIKEALGFMRNQ 369
TPT + ++ + +KGPS T++ ++EAL ++ +
Sbjct: 301 TPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEE 354
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 58.2 bits (139), Expect = 7e-08
Identities = 74/315 (23%), Positives = 135/315 (42%), Gaps = 43/315 (13%)
Query: 4 FVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLK-GFINDDD 62
F E E+ E+ D GE ++ +E ++E EE + + E+G K GF +
Sbjct: 422 FEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGF---EG 478
Query: 63 DEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLED--------DDFDLIEENLGVKVKR 114
+ E +EG+ SE+D K+ K+ + + E+ DD + E K
Sbjct: 479 SCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKE 538
Query: 115 GQKYRRVKKMSDDEDDDEEEYGKE-EHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEE 173
++ K+ +D + + E G E E E+ + +++ ++G +E E + E EE
Sbjct: 539 SEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENV----LDKELEE 594
Query: 174 EDDEESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEA---QEIFGVDFDYDEFEKY- 229
D E S+ +D D + L + ++ +D +E +++F + D E E+Y
Sbjct: 595 NDSENSEFED---DGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYA 651
Query: 230 --------------NEYDEEL-EEEYEYEDDEAEG-EIRVRPKKTTKKRVSRRSIFEMYE 273
+ DE+L EE + ED++A+G E+ +K + S +F+ E
Sbjct: 652 DEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEE 711
Query: 274 PSELESSHLTDQDNE 288
S S L D +E
Sbjct: 712 DS---SEKLFDDSDE 723
Score = 57.0 bits (136), Expect = 2e-07
Identities = 49/183 (26%), Positives = 86/183 (46%), Gaps = 28/183 (15%)
Query: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQ--DEQGNLKGFIND 60
+F E+ E+ +E E E+ V K +EE D + E E++ ++ DE+G+ + F
Sbjct: 564 EFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREF--- 620
Query: 61 DDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRR 120
D+D DE EE+E + +D+ D ED+++ E+ L K+ ++
Sbjct: 621 DEDSDEKEEEEDTYEKVFDDE-----------SDEKEDEEY-ADEKGLEAADKKAEEGDA 668
Query: 121 VKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESD 180
+K+ ++ DD E+E + E E E++F+D + E +EEED E
Sbjct: 669 DEKLFEESDDKEDE-DADGKEVEDADEKLFEDDDSNE----------KLFDEEEDSSEKL 717
Query: 181 IDD 183
DD
Sbjct: 718 FDD 720
Score = 56.6 bits (135), Expect = 2e-07
Identities = 44/182 (24%), Positives = 87/182 (47%), Gaps = 23/182 (12%)
Query: 6 ESEAEESEE-EYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDE 64
E E +SE E+ D+G ++K ++EE + E +E++ + ++E+ + +D+ DE
Sbjct: 591 ELEENDSENSEFEDDG------SEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDE 644
Query: 65 DEGEE---DEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRV 121
E EE ++G ++ D + + G K D ED+D D G +V+
Sbjct: 645 KEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDAD------GKEVEDAD----- 693
Query: 122 KKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEE--EEEDDEES 179
+K+ +D+D +E+ + +EE E + ++ + G E P++ DD++
Sbjct: 694 EKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGPLSTGSSFILSSDDDDD 753
Query: 180 DI 181
DI
Sbjct: 754 DI 755
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 58.2 bits (139), Expect = 7e-08
Identities = 74/315 (23%), Positives = 135/315 (42%), Gaps = 43/315 (13%)
Query: 4 FVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLK-GFINDDD 62
F E E+ E+ D GE ++ +E ++E EE + + E+G K GF +
Sbjct: 422 FEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGF---EG 478
Query: 63 DEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLED--------DDFDLIEENLGVKVKR 114
+ E +EG+ SE+D K+ K+ + + E+ DD + E K
Sbjct: 479 SCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKE 538
Query: 115 GQKYRRVKKMSDDEDDDEEEYGKE-EHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEE 173
++ K+ +D + + E G E E E+ + +++ ++G +E E + E EE
Sbjct: 539 SEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENV----LDKELEE 594
Query: 174 EDDEESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEA---QEIFGVDFDYDEFEKY- 229
D E S+ +D D + L + ++ +D +E +++F + D E E+Y
Sbjct: 595 NDSENSEFED---DGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYA 651
Query: 230 --------------NEYDEEL-EEEYEYEDDEAEG-EIRVRPKKTTKKRVSRRSIFEMYE 273
+ DE+L EE + ED++A+G E+ +K + S +F+ E
Sbjct: 652 DEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEE 711
Query: 274 PSELESSHLTDQDNE 288
S S L D +E
Sbjct: 712 DS---SEKLFDDSDE 723
Score = 57.0 bits (136), Expect = 2e-07
Identities = 49/183 (26%), Positives = 86/183 (46%), Gaps = 28/183 (15%)
Query: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQ--DEQGNLKGFIND 60
+F E+ E+ +E E E+ V K +EE D + E E++ ++ DE+G+ + F
Sbjct: 564 EFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREF--- 620
Query: 61 DDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRR 120
D+D DE EE+E + +D+ D ED+++ E+ L K+ ++
Sbjct: 621 DEDSDEKEEEEDTYEKVFDDE-----------SDEKEDEEY-ADEKGLEAADKKAEEGDA 668
Query: 121 VKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESD 180
+K+ ++ DD E+E + E E E++F+D + E +EEED E
Sbjct: 669 DEKLFEESDDKEDE-DADGKEVEDADEKLFEDDDSNE----------KLFDEEEDSSEKL 717
Query: 181 IDD 183
DD
Sbjct: 718 FDD 720
Score = 56.6 bits (135), Expect = 2e-07
Identities = 44/182 (24%), Positives = 87/182 (47%), Gaps = 23/182 (12%)
Query: 6 ESEAEESEE-EYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDE 64
E E +SE E+ D+G ++K ++EE + E +E++ + ++E+ + +D+ DE
Sbjct: 591 ELEENDSENSEFEDDG------SEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDE 644
Query: 65 DEGEE---DEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRV 121
E EE ++G ++ D + + G K D ED+D D G +V+
Sbjct: 645 KEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDAD------GKEVEDAD----- 693
Query: 122 KKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEE--EEEDDEES 179
+K+ +D+D +E+ + +EE E + ++ + G E P++ DD++
Sbjct: 694 EKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGPLSTGSSFILSSDDDDD 753
Query: 180 DI 181
DI
Sbjct: 754 DI 755
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 58.2 bits (139), Expect = 7e-08
Identities = 42/129 (32%), Positives = 67/129 (51%), Gaps = 21/129 (16%)
Query: 4 FVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDD 63
+++ E +E + + EV V+EE++DEE E+E D+ DE G + F +++DD
Sbjct: 144 YLDGYDREDQEAPDSDAEV------DGVDEEEEDEEGEDEE-DEDDEDGEEEEF-DEEDD 195
Query: 64 EDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKK 123
EDE E GD +DD ++ + D+ ED+D D EE G KR K+
Sbjct: 196 EDEDVE------GDEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKR-------KR 242
Query: 124 MSDDEDDDE 132
+DDE +D+
Sbjct: 243 ETDDEGEDD 251
Score = 42.7 bits (99), Expect = 0.003
Identities = 38/164 (23%), Positives = 69/164 (42%), Gaps = 42/164 (25%)
Query: 17 NDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDEDEGEEDEGSDSG 76
ND E V ++ + + D E++E D + G ++++++++EGE++E D
Sbjct: 129 NDYRESVFKLLPQLTYLDGYDREDQEAPDSDAEVDG-----VDEEEEDEEGEDEEDEDDE 183
Query: 77 DSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDEDDDEEEYG 136
D E++ FD E+DD D +D + DE++
Sbjct: 184 DGEEE---------EFD---EEDDED-----------------------EDVEGDEDDDE 208
Query: 137 KEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESD 180
E E+E +E +D + +E +E E + E DDE D
Sbjct: 209 VSEEEEEFGLDE--EDEDEDEDEEEEEGGKGEKRKRETDDEGED 250
Score = 42.0 bits (97), Expect = 0.005
Identities = 39/136 (28%), Positives = 60/136 (44%), Gaps = 35/136 (25%)
Query: 118 YRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDE 177
Y R + + D D + + +EE ++E EE D +GEE E +EEDDE
Sbjct: 148 YDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEE-----------EEFDEEDDE 196
Query: 178 ESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEE-- 235
+ D++ D+D D + E +E FG+D + DE E +E +EE
Sbjct: 197 DEDVEG---DED-----------------DDEVSEEEEEFGLD-EEDEDEDEDEEEEEGG 235
Query: 236 -LEEEYEYEDDEAEGE 250
E+ DDE E +
Sbjct: 236 KGEKRKRETDDEGEDD 251
Score = 39.7 bits (91), Expect = 0.026
Identities = 35/113 (30%), Positives = 57/113 (50%), Gaps = 16/113 (14%)
Query: 150 FQDGEGEEGQEA--MEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLKKPKWRKKLPGYTD 207
+ DG E QEA +A + +EEEED+E D +D D+DG+ + D
Sbjct: 144 YLDGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEED-EDDEDGEEEE-----------FD 191
Query: 208 AALQEAQEIFGVDFDYDEFEKYNEY--DEELEEEYEYEDDEAEGEIRVRPKKT 258
E +++ G + D + E+ E+ DEE E+E E E++E G+ R ++T
Sbjct: 192 EEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRET 244
Score = 38.9 bits (89), Expect = 0.044
Identities = 20/68 (29%), Positives = 42/68 (61%), Gaps = 5/68 (7%)
Query: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDD 62
+F E + E+ + E +++ + V ++F +E+D++E+E D+++E+G KG +
Sbjct: 189 EFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDE----DEEEEEGG-KGEKRKRE 243
Query: 63 DEDEGEED 70
+DEGE+D
Sbjct: 244 TDDEGEDD 251
Score = 38.5 bits (88), Expect = 0.057
Identities = 25/90 (27%), Positives = 45/90 (50%), Gaps = 5/90 (5%)
Query: 94 DRLEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDG 153
DR + + D E GV + + ++ DDED +EEE+ +E+ E E + + D
Sbjct: 149 DREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDE 208
Query: 154 EGEEGQEAMEAPMAPPEEEEEDDEESDIDD 183
EE +E EE+E++DE+ + ++
Sbjct: 209 VSEEEEE-----FGLDEEDEDEDEDEEEEE 233
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 58.2 bits (139), Expect = 7e-08
Identities = 78/346 (22%), Positives = 125/346 (36%), Gaps = 55/346 (15%)
Query: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDD 62
D + E EE EEE +E E + EE+E+ D G ++
Sbjct: 186 DGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQGHEE 245
Query: 63 DEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVK 122
D+D+ ++D D D +DDV + R + R + + E+ R +R
Sbjct: 246 DDDDDDDD---DDDDDDDDVSIEYRHQA---HRHQGHGIEEDEDVSDGHHHRDPSHRHRS 299
Query: 123 KMSDDEDDDE--EEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESD 180
DD DDD+ EYG + H + +E + GE + +EEED++ S
Sbjct: 300 HEEDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVS- 358
Query: 181 IDDFIVDDDGQPLKKPKWRKKLPGYTDAAL---QEAQEIFGVDFDY------------DE 225
+W + P + L +E +E V F + DE
Sbjct: 359 --------------TERWHQG-PQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDE 403
Query: 226 FEKYNEYDEELEEEYEY-----EDDEAEGEI-------RVRPKKTTKKRVSRRSIFEMYE 273
+ +EY E+ + + ED+E E+ R + R SI EM
Sbjct: 404 EDFQDEYKTEVPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIKEM-- 461
Query: 274 PSELESSHLTDQD-NEIRATDLPERFQLRSIPVKGAEDDELEEEAD 318
S H +D + +R D E + P EDDE E+ +
Sbjct: 462 -SHHPPGHTVVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGE 506
Score = 56.6 bits (135), Expect = 2e-07
Identities = 48/190 (25%), Positives = 84/190 (44%), Gaps = 22/190 (11%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDED 65
+S+ E+ ++EY E VP V E+D+E E + DE+
Sbjct: 400 KSDEEDFQDEYKTE---VPHHHHHRVPREEDEEVSAELGHQAPSHR-------QSHQDEE 449
Query: 66 EGEEDEGSDSGDSEDDVGHKK-------RKRTSFDDRLEDDDFDLIEENLGVKVKRGQKY 118
G GS S GH RK S +++ +++D EE+ + +
Sbjct: 450 TGHGQRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGT 509
Query: 119 RRVKKMSDDEDDDEEEYG-----KEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEE 173
+ +DE+D+EE +G +EE E++ EE +D E E + + AP++P EE
Sbjct: 510 HHGSRDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEE 569
Query: 174 EDDEESDIDD 183
E++EE +++
Sbjct: 570 EEEEEEGLEE 579
Score = 47.8 bits (112), Expect = 9e-05
Identities = 67/307 (21%), Positives = 125/307 (40%), Gaps = 36/307 (11%)
Query: 32 EEEDDDEEEEEENL----DDQDEQGNLKGFINDDDDEDEGEE---DEGSDSGDSEDDVGH 84
E+ED+D +E +L QD + +G ++ + G + G S D+ED H
Sbjct: 89 EKEDEDVSKEYGHLLPGHRSQDHKVGDEGVSGEEVFAEHGGQARGHRGHGSEDTEDSAEH 148
Query: 85 KKR--KRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDEDDDEE--------E 134
+ S + ED+D + E+ ++ G + + +E+++EE E
Sbjct: 149 RHHLPSHRSHSHQDEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTE 208
Query: 135 YGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLK 194
YG + H E +D + +G P + EEDD++ D DD DDD
Sbjct: 209 YGHQAHRHRGHGSE--EDEDVSDGHH-HHGPSHRHQGHEEDDDDDDDDD---DDDDDDDV 262
Query: 195 KPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEYEDDEAE---GEI 251
++R + + ++E +++ D ++ ++E+ + +DD+ G
Sbjct: 263 SIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHRSHEED-----DNDDDDVSTEYGHQ 317
Query: 252 RVRPKKTTKKRVSRRS-IFEMYEPSELESSHLTDQDNEIRATDLPERFQLRSIPV-KGAE 309
R + K+ V S + P H ++++E +T ER+ V G
Sbjct: 318 AHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVST---ERWHQGPQHVHHGLV 374
Query: 310 DDELEEE 316
D+E EEE
Sbjct: 375 DEEEEEE 381
Score = 45.4 bits (106), Expect = 5e-04
Identities = 34/129 (26%), Positives = 60/129 (46%), Gaps = 26/129 (20%)
Query: 10 EESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDEDEGEE 69
++ +EE +EG + + ++ EEED +EEEEEE+ + ++E+ + ++ D E+E EE
Sbjct: 515 DQEDEEDEEEGHGLS-LNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEE 573
Query: 70 DEGSDSGDSEDDVGHKKRKRTSFDDRLEDDD--FDLIEENLGVKVKRGQKYRRVKKMSDD 127
+EG LE+D+ F +I L + + G + D
Sbjct: 574 EEG-----------------------LEEDEPRFTIIPNPLDRREEAGGASSEEESGEDT 610
Query: 128 EDDDEEEYG 136
D +EYG
Sbjct: 611 GPQDAQEYG 619
Score = 39.7 bits (91), Expect = 0.026
Identities = 58/293 (19%), Positives = 109/293 (37%), Gaps = 49/293 (16%)
Query: 13 EEEYNDEGEVVPRVTKKFVEEEDDDEEEEE-------ENLDDQDEQGNLKGFINDDDDED 65
EE+ ND+ +V + +D +EE E ++ D QG+ ++++DED
Sbjct: 301 EEDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHR----DEEEDED 356
Query: 66 EGEE--------------DEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVK 111
E DE + + GH + +++DF ++ +
Sbjct: 357 VSTERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHKSDEEDF---QDEYKTE 413
Query: 112 VKRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPP-- 169
V + RV + D+E E + H + EE G G+ G E PP
Sbjct: 414 VPH-HHHHRVPREEDEEVSAELGHQAPSHRQSHQDEET---GHGQRGS-IKEMSHHPPGH 468
Query: 170 ------------EEEEEDDEESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIF 217
+ EEE ++E D DD+ + D ++ +E
Sbjct: 469 TVVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDE--EDEEEGH 526
Query: 218 GVDFDYDEFEKYNEYDEELEEEYEYEDDEAEGEIRVRPKKTTKKRVSRRSIFE 270
G+ + +E E+ ++ +EE EE+ E ++ AE + P + ++ + E
Sbjct: 527 GLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEGLEE 579
Score = 35.0 bits (79), Expect = 0.63
Identities = 24/78 (30%), Positives = 36/78 (46%), Gaps = 12/78 (15%)
Query: 3 DFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEEN----------LDDQDEQG 52
D E E EE EE + EV ++ EEE+++EE EE+ LD ++E G
Sbjct: 539 DKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEGLEEDEPRFTIIPNPLDRREEAG 598
Query: 53 NLKGFINDDDDEDEGEED 70
++ ED G +D
Sbjct: 599 GASS--EEESGEDTGPQD 614
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 57.4 bits (137), Expect = 1e-07
Identities = 103/525 (19%), Positives = 217/525 (41%), Gaps = 89/525 (16%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDED 65
E E E E+E ++ E+ R ++ ++E+++ E+EE + +Q+E+ ++
Sbjct: 327 EKELREQEKELREQKEL--REQEEQMQEQEEKMWEQEEKMREQEEK---------MWRQE 375
Query: 66 EGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMS 125
E ++ + E + ++ + D+RL + + + E+ + + +V+KM
Sbjct: 376 ERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE--------KMWEQVEKMR 427
Query: 126 DDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFI 185
+++ E+E + E++ EE ++ E + +E E M EE+ + EE+
Sbjct: 428 EEKKMQEQEKKTRDQEEKMQEEERIREREKKMREE--EETMREQEEKMQKQEEN------ 479
Query: 186 VDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEEL-EEEYEYED 244
W ++ + L E +E E EK E +E++ E+E + D
Sbjct: 480 -----------MWEQEEKEWQQQRLPEQKEKLW------EQEKMQEQEEKIWEQEEKIRD 522
Query: 245 DEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEIRATDLPERFQLRSIP 304
E E+ + KK ++ R +M+E E +D E + D ER + ++
Sbjct: 523 QE---EMWGQEKKMWRQEKMREQEDQMWEQEE------KMRDQEQKMWDQEERMEKKT-- 571
Query: 305 VKGAEDDELEEEADWIYRNAFATPTISLQESCDYLDRGQPASSFSRKGPSTIQKIKEALG 364
+ +E+ W +E +R + R+ +++ +E +
Sbjct: 572 -------QEQEKKTW-----------DQEEKMREEERMREREKKMREEEEMMREQEEKMQ 613
Query: 365 FMRNQHFEVPFIAFYRKEYVEPELHINDLW----RVWQWDEK-WTQLRI--RKENLTRLF 417
+ E + ++E ++ + +W ++W+ +EK W Q R+ +KE L
Sbjct: 614 EQEEKMQEQEEKMWEQEEKMQEQ--EEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE-H 670
Query: 418 EKMQAY-----QYEQISADPDKPLADGIRALDTTDMERLKDVQSMDELKDVYNHFLLYYG 472
EKMQ Q E+I + T D E++++ +SM E +
Sbjct: 671 EKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMR 730
Query: 473 RDIPKMQNAAKASRKKLKRVREEGDEEGEGDEAEDEEQRGPELKQ 517
KMQ + +++ + + E+ ++ E +E E+QR PE K+
Sbjct: 731 EQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKE 775
Score = 53.5 bits (127), Expect = 2e-06
Identities = 96/538 (17%), Positives = 230/538 (42%), Gaps = 56/538 (10%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEE--ENLDDQDEQGNLKGFINDDDD 63
E + E E++ D+ E + ++ E+E+ E+E+ E ++ E+ ++
Sbjct: 382 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQ-------- 433
Query: 64 EDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKK 123
E E + + + E+ + +++K ++ + + + + ++ + + +++++ +
Sbjct: 434 EQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 493
Query: 124 MSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAM---EAPMAPPEEE--EEDDEE 178
E E+E +E+ EK EE +D E GQE + M E++ E++++
Sbjct: 494 PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 553
Query: 179 SDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEE 238
D + + D + + KK + ++K + ++E + + E EK +EE+
Sbjct: 554 RDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERM-------REREKKMREEEEMMR 606
Query: 239 EYEYEDDEAEGEIRVRPKKTTKKRVSRRSIFE-MYEPSELESSHLTDQDNEI-RATDLPE 296
E E + E E +++ + +K ++ + E M+E E + +Q+ ++ LPE
Sbjct: 607 EQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE----KMWEQEEKMWEQQRLPE 662
Query: 297 RFQLRSIPVKGAEDDELEEEADWIYRNAFATPTISLQESCDYLDRGQPASSFSRKGPSTI 356
+ + K E ++++E+ + I+ QE + R+
Sbjct: 663 QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRERE--- 719
Query: 357 QKIKEALGFMRNQHFEVPFIAFYRKEYVEPELHINDLW----RVWQWDEK-WTQLRI--R 409
+K++E MR Q ++ +++ + + ++W ++W+ +EK W Q R+ +
Sbjct: 720 KKMREEEEMMREQEEKM------QEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQ 773
Query: 410 KENLTRLFEKMQAY-----QYEQISADPDKPLADGIRALDTTDMERLKDVQSMDELKDVY 464
KE L EKMQ Q E++ +K + + R ++ + + + ++
Sbjct: 774 KEKLWE-HEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMW 832
Query: 465 NHFLLYYGRDIP------KMQNAAKASRKKLKRVREEGDEEGEGDEAEDEEQRGPELK 516
+G++ KM+ + +K++ E+ + E ++E+ RG E K
Sbjct: 833 GQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 50.8 bits (120), Expect = 1e-05
Identities = 89/550 (16%), Positives = 228/550 (41%), Gaps = 54/550 (9%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDD-- 63
E + E EE+ ++ E + R ++ E+E E+E++ D ++ + + ++
Sbjct: 354 EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM 413
Query: 64 --------------------EDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDL 103
E E + + + E+ + +++K ++ + + + +
Sbjct: 414 REQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKM 473
Query: 104 IEENLGVKVKRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEA-- 161
++ + + +++++ + E E+E +E+ EK EE +D E GQE
Sbjct: 474 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 533
Query: 162 -MEAPMAPPEEE--EEDDEESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFG 218
+ M E++ E++++ D + + D + + KK + ++K + ++E + +
Sbjct: 534 WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERM-- 591
Query: 219 VDFDYDEFEKYNEYDEELEEEYEYEDDEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELE 278
E EK +EE+ E E + E E +++ + +K ++ + E E +
Sbjct: 592 -----REREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQ---EEKMQEQEEKMWEQ 643
Query: 279 SSHLTDQDNEI-RATDLPERFQLRSIPVKGAEDDELEEEADWIYRNAFATPTISLQESCD 337
+ +Q+ ++ LPE+ + K E ++++E+ + I+ QE
Sbjct: 644 EEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKT 703
Query: 338 YLDRGQPASSFSRKGPSTIQKIKEALGFMRNQHFEVPFIAFYRKEYVEPELHINDLW--- 394
+ R+ +K++E MR Q ++ +++ + + ++W
Sbjct: 704 WDQEKMREEESMRERE---KKMREEEEMMREQEEKM------QEQEEKMQEQEEEMWEQE 754
Query: 395 -RVWQWDEK-WTQLRIRKENLTRLFEKMQAYQYEQISADPDKPLADGIRALDTTDMERLK 452
++W+ +EK W Q R+ E +L+E + + E+I +K + + R +
Sbjct: 755 EKMWEQEEKMWEQQRL-PEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQ 813
Query: 453 DVQSMDELKDVYNHFLLYYGRDIPKMQNAAKASRKKLKRVREEGDEEGEGDEAEDEEQRG 512
+ + + + ++ +G++ KM + + +++ E+ + E ++E+ RG
Sbjct: 814 EEKMRGQEEKMWGQEEKMWGQE-EKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRG 872
Query: 513 PELKQASRRD 522
E K + +
Sbjct: 873 QEEKMREQEE 882
Score = 41.6 bits (96), Expect = 0.007
Identities = 51/277 (18%), Positives = 127/277 (45%), Gaps = 14/277 (5%)
Query: 1 MSDFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEE----EEENLDDQDEQGNLKG 56
M + E E+ E+ + E ++ + K + +EE E+E E++ L +Q E+ L
Sbjct: 612 MQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEK--LWE 669
Query: 57 FINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQ 116
+ E E++E + + ++ K+T +++ +++ + E ++ +
Sbjct: 670 HEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEE-SMREREKKMREEEEM 728
Query: 117 KYRRVKKMSDDED---DDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEE 173
+ +KM + E+ + EEE ++E + E++++ E +E + E+E+
Sbjct: 729 MREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK 788
Query: 174 EDDEESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFD-YDEFEKYNEY 232
++E + D GQ K +K+ G + + ++++G + + + EK
Sbjct: 789 IWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQ 848
Query: 233 DEELEEEYEYEDD---EAEGEIRVRPKKTTKKRVSRR 266
+E++EE+ + +++ E E ++R + +K ++ R
Sbjct: 849 EEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMR 885
>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
[Homo sapiens]
Length = 666
Score = 57.4 bits (137), Expect = 1e-07
Identities = 50/204 (24%), Positives = 90/204 (44%), Gaps = 22/204 (10%)
Query: 2 SDFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDD 61
SD +E S+ E ND +V + +++D+ + + +G+ K
Sbjct: 84 SDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAH---S 140
Query: 62 DDEDEGEEDEGSDSGDSE-DDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVK------- 113
DDE G ED+ S D + + ++R + S +D+L++ D D +N + +
Sbjct: 141 DDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQLSDDE 200
Query: 114 RGQKYRRVKKMSDDE------DDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMA 167
R Q K SDDE +DDE++ +E + + EE Q+ + E Q + E
Sbjct: 201 RQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEHRH 260
Query: 168 PPEEEEEDDEE-----SDIDDFIV 186
+EEE+D + SD +D ++
Sbjct: 261 SDDEEEQDHKSESARGSDSEDEVL 284
Score = 56.2 bits (134), Expect = 3e-07
Identities = 66/278 (23%), Positives = 111/278 (39%), Gaps = 60/278 (21%)
Query: 1 MSDFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDE------EEEEENLDDQDEQGNL 54
+SD + E E+ +D+ V + DD+E EE+ +N DD+ Q +
Sbjct: 196 LSDDERQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASD 255
Query: 55 KGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKR 114
+ + DD+E++ + E + DSED+V KRK D D D ++ ++N G
Sbjct: 256 EEHRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNSGTMDLF 315
Query: 115 GQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEE-----GQEAMEAPMAPP 169
G A++I +GE+ GQ E +
Sbjct: 316 GG-----------------------------ADDISSGSDGEDKPPTPGQPVDENGLPQD 346
Query: 170 EEEEEDDEESDIDDFI--VDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFE 227
++EEE E+ I+ I V+ D L + KLP + L F + DEFE
Sbjct: 347 QQEEEPIPETRIEVEIPKVNTD---LGNDLYFVKLPNF----LSVEPRPFDPQYYEDEFE 399
Query: 228 KYNEYDEELEEEYEYEDDEAEGEIRVRPKKTTKKRVSR 265
DEE+ D+E ++++ + T + R+ R
Sbjct: 400 -----DEEM------LDEEGRTRLKLKVENTIRWRIRR 426
Score = 53.5 bits (127), Expect = 2e-06
Identities = 74/317 (23%), Positives = 126/317 (39%), Gaps = 65/317 (20%)
Query: 1 MSDFVESEAE-ESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLD------DQDEQGN 53
M D S+A+ E+E + +D G + D D+E + DQDE+G+
Sbjct: 4 MEDLFGSDADSEAERKDSDSGS-----------DSDSDQENAASGSNASGSESDQDERGD 52
Query: 54 L-----KGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENL 108
K DD +++ GSD+ D R S ED+D ++++
Sbjct: 53 SGQPSNKELFGDDSEDEGASHHSGSDNHSERSD----NRSEASERSDHEDNDPSDVDQHS 108
Query: 109 GVKVKRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAP 168
G + +DDED+ G H + +E+ D E + G+E
Sbjct: 109 GSEAP-----------NDDEDEGHRSDGGSHHSEAEGSEKAHSDDE-KWGREDKSDQSDD 156
Query: 169 PEEEEEDDEE----SDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYD 224
+ + DDEE SD D DD + ++ ++ P +D Q+ E + D +
Sbjct: 157 EKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEER-PQLSDDERQQLSEEEKANSDDE 215
Query: 225 -------EFEKYNEYDEEL-----EEEYEYEDDEAEGEIRVRPKKTTKKRVSRRSIFEMY 272
+ EK N DEE EE+ + DDE RP+ + ++ R S E
Sbjct: 216 RPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDE-------RPQASDEEH--RHSDDEEE 266
Query: 273 EPSELESSHLTDQDNEI 289
+ + ES+ +D ++E+
Sbjct: 267 QDHKSESARGSDSEDEV 283
Score = 34.3 bits (77), Expect = 1.1
Identities = 34/122 (27%), Positives = 52/122 (42%), Gaps = 32/122 (26%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEE-EENLDDQDEQGNLKGFINDD--- 61
ES+ E+ + G ++ ++E + DEEEE EE++ + KG I ++
Sbjct: 550 ESQQRRMREKQHQRG-----LSASYLEPDRYDEEEEGEESISLAAIKNRYKGGIREERAR 604
Query: 62 ---DDEDEGEED----------------EGSDSGD---SEDDVGHKKRKRTSF-DDRLED 98
D DEG E+ EG SG +DD +KK K+ D+ ED
Sbjct: 605 IYSSDSDEGSEEDKAQRLLKAKKLTSDEEGEPSGKRKAEDDDKANKKHKKYVISDEEEED 664
Query: 99 DD 100
DD
Sbjct: 665 DD 666
Score = 33.5 bits (75), Expect = 1.8
Identities = 37/180 (20%), Positives = 64/180 (35%), Gaps = 2/180 (1%)
Query: 122 KKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDI 181
+K SD D + + A E QD G+ GQ + + E+E S
Sbjct: 18 RKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFGDDSEDEGASHHSGS 77
Query: 182 DDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELE-EEY 240
D+ D + + + +D E D D + E E E
Sbjct: 78 DNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEK 137
Query: 241 EYEDDEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEIRATDLPERFQL 300
+ DDE G + ++ +++ E + S+ + +D D +++ TD ER QL
Sbjct: 138 AHSDDEKWGR-EDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQL 196
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 57.0 bits (136), Expect = 2e-07
Identities = 49/215 (22%), Positives = 95/215 (44%), Gaps = 32/215 (14%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLD------------------- 46
ESE + + E E R +K ++D D E + E+ +
Sbjct: 303 ESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHS 362
Query: 47 -DQDEQGNLKGFINDDDDEDEGEED-----EGSDSGDSEDDVGHKKRKRTSFDDRLEDDD 100
D +E+ + K ++ D+DE EGEE+ + + DSED+ +K D +D D
Sbjct: 363 SDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSD-ADDSD 421
Query: 101 FDLIEENLGVKVK---RGQKYRRVKKMSDDEDDDEEEYGKEE---HEKEAIAEEIFQDGE 154
D + + G + K + K++SD ++++++ +G + +E+E + +IF +
Sbjct: 422 SDAVSDKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESG 481
Query: 155 GEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDD 189
EE +E EEE+ + + + +D DD+
Sbjct: 482 DEEEEEFTGFNQEDLEEEKGETQVKEAEDSDSDDN 516
Score = 50.8 bits (120), Expect = 1e-05
Identities = 62/276 (22%), Positives = 108/276 (39%), Gaps = 37/276 (13%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDED 65
ESE + + E E +P+ E ED + ++ +++ + + D E
Sbjct: 251 ESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVS------DSES 304
Query: 66 EGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRV---- 121
EG + + ++ED HK++ + D E+ D +N ++
Sbjct: 305 EGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSD 364
Query: 122 ------KKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEED 175
KK D D+DE+E +E+ K A + D E EE A ++ + ++ +
Sbjct: 365 SEEEEHKKQKMDSDEDEKEGEEEKVAKRKAA--VLSDSEDEEKASAKKSRVVSDADDSDS 422
Query: 176 DEESD--------IDDFIVDDDGQPLK-KPKWRKKLPGYTDAALQEAQ----EIFGVDFD 222
D SD I ++ G+ L K K L G + E + +IFG D
Sbjct: 423 DAVSDKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGD 482
Query: 223 YDEFEKYNEYDEELEEE------YEYEDDEAEGEIR 252
+E E E+LEEE E ED +++ I+
Sbjct: 483 EEEEEFTGFNQEDLEEEKGETQVKEAEDSDSDDNIK 518
Score = 43.5 bits (101), Expect = 0.002
Identities = 60/295 (20%), Positives = 106/295 (35%), Gaps = 46/295 (15%)
Query: 7 SEAEESEEEYNDEGEVVPRVTKKFVEEED--------DDEEEEEENLDDQDEQGNLKGFI 58
S SE E +D + +P+ E D D E EE D D + +
Sbjct: 44 SVERHSENETSDREDGLPKGHHVTDSENDEPLNLNASDSESEELHRQKDSDSESEERAEP 103
Query: 59 NDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKY 118
D E+E GSDS E RK D E +L+ +
Sbjct: 104 PASDSENEDVNQHGSDSESEE------TRKLPGSDSENE----ELLNGH----------- 142
Query: 119 RRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAM----EAPMAPPEEEEE 174
SD E++D ++ + E E + + D E E+ + E+ P + +
Sbjct: 143 -----ASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASD 197
Query: 175 DDEESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDE 234
+ E + D + + L KP+ +D+ +E D + +E K D
Sbjct: 198 SENEEPPKPRMSDSESEELPKPQ-------VSDSESEEPPRHQASDSENEELPKPRISDS 250
Query: 235 ELEEEYEYEDDEAEGEIRVRPK-KTTKKRVSRRSIFEMYEPSELESSHLTDQDNE 288
E E+ ++ ++E E +P+ ++ R+ E EL ++D ++E
Sbjct: 251 ESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESE 305
Score = 33.9 bits (76), Expect = 1.4
Identities = 25/91 (27%), Positives = 47/91 (51%), Gaps = 3/91 (3%)
Query: 2 SDFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDD 61
SD E +E ++ N+E ++ ++ EEE+ + E+ D+++E+ GF N +
Sbjct: 438 SDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEE--FTGF-NQE 494
Query: 62 DDEDEGEEDEGSDSGDSEDDVGHKKRKRTSF 92
D E+E E + ++ DS+ D K+ K F
Sbjct: 495 DLEEEKGETQVKEAEDSDSDDNIKRGKHMDF 525
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 56.6 bits (135), Expect = 2e-07
Identities = 76/352 (21%), Positives = 130/352 (36%), Gaps = 53/352 (15%)
Query: 2 SDFVESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDD 61
S+ VE+ E E + EG P K+ E + E E E D+ + +G
Sbjct: 1887 SEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEG-----AEAQ 1941
Query: 62 DDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRV 121
+ E+ +E EG +SE + + + E +D + +E + + G+
Sbjct: 1942 EAEEAAQEAEGQTQPESEVIESQEAEEEA----QPESEDVEALEVEVETQEAEGEAQPES 1997
Query: 122 KKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQE-----------------AMEA 164
+ + E + E + +EE + E+ E EGEE QE +EA
Sbjct: 1998 EDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEA 2057
Query: 165 PMAPPEEEEED-----------DEESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEA 213
P A E +E + E D+D + + QP + + G EA
Sbjct: 2058 PEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEG-------EA 2110
Query: 214 QEIFGVDFDYDEFEKYNEYD----EELEEEYEYEDDEAEGEIRVRPKKTTKKRVSRRSIF 269
Q+ G++ E E E + E E E + E + E + + + + +
Sbjct: 2111 QKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAE 2170
Query: 270 EMYEPSELESSHLTDQDNEIR----ATDLPERFQLRSIPVKGAEDDELEEEA 317
E +P ELE + + E + + PE ++G E E EEEA
Sbjct: 2171 EEAQP-ELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEA 2221
Score = 49.3 bits (116), Expect = 3e-05
Identities = 64/313 (20%), Positives = 123/313 (39%), Gaps = 26/313 (8%)
Query: 6 ESEAEESEEEYND-EGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDE 64
E EA+E+E E + EGE P +E + + + E E ++ + +G + + E
Sbjct: 2061 EEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPE 2120
Query: 65 DEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKM 124
EGE S+ ++ + G + + + +D + + E+ G++ + ++ + +
Sbjct: 2121 TEGEAQPESEGIEAPEAEGEAQPESEGVE--AQDAEGEAQPESEGIEAQEAEEEAQPELE 2178
Query: 125 SDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDF 184
+ + E G+ + E E I E +GE + E +EAP A EEE E ++
Sbjct: 2179 GVEAPEAE---GEAQPESEGI-EAPEAEGEAQPELEGVEAPEA---EEEAQPEPEGVETP 2231
Query: 185 IVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEYED 244
+ + QP + + + + G +L + Q E+ +E + E+
Sbjct: 2232 EAEGEAQPESEGETQGEKKGSPQVSLGDGQS-----------EEASESSSPVPEDRPTPP 2280
Query: 245 DEAEGEI-RVRPKKTTKKRVSRRSIFEMYEPSELESSHL----TDQDNEIRATDLPERFQ 299
G+ RP T SR S + + E+ H+ D + T ER
Sbjct: 2281 PSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKSTGTPHAERKA 2340
Query: 300 LRSIPVKGAEDDE 312
R P + E
Sbjct: 2341 TRMYPESSTSEQE 2353
Score = 48.9 bits (115), Expect = 4e-05
Identities = 67/277 (24%), Positives = 110/277 (39%), Gaps = 62/277 (22%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDED 65
+S+ E E EGE P E + E E D Q+ +G + + ++
Sbjct: 1828 QSDGAEGIEAPEAEGEAQP---------ESEGVEAPEAEGDAQEAEGEAQ----PESEDV 1874
Query: 66 EGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRR----- 120
E E EG +SE D + ++++ E+ G + +K +
Sbjct: 1875 EAPEAEGEAQPESE-------------DVETPEAEWEVQPESEGAEAPEAEKEAQPETES 1921
Query: 121 VKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGE--------EGQEAMEAPMAPPEEE 172
V+ + + +D+ E G E E AEE Q+ EG+ E QEA E A PE E
Sbjct: 1922 VEALETEGEDEPESEGAEAQE----AEEAAQEAEGQTQPESEVIESQEAEEE--AQPESE 1975
Query: 173 EEDDEESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQ-EIFGVDFD-YDEFEKYN 230
+ + E +++ + + QP + + G A +EAQ E GV+ E E+
Sbjct: 1976 DVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQ 2035
Query: 231 EYDEELEE---------------EYEYEDDEAEGEIR 252
E + E ++ E E E EAEGE++
Sbjct: 2036 EVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQ 2072
Score = 42.4 bits (98), Expect = 0.004
Identities = 66/274 (24%), Positives = 98/274 (35%), Gaps = 31/274 (11%)
Query: 48 QDEQGNLKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEEN 107
Q +G L ++ DEGE+ EGS +R D +L + + D + +
Sbjct: 1724 QGAEGGLGPGLSQGPGVDEGEDGEGS------------QRLNRDKDPKLGEAEGDAMAQ- 1770
Query: 108 LGVKVKRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAE--EIFQDGEGEEGQEAMEAP 165
R K + E E G+ E E E I+E E G G E EA
Sbjct: 1771 -----------EREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAA 1819
Query: 166 MAPPEEEEEDDEESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQ-EIFGVDFDYD 224
++ + D I+ + + QP + + G A EAQ E V+
Sbjct: 1820 AGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEA 1879
Query: 225 EFEKYNEYDEELEEEYEYE-DDEAEGEIRVRPKKTTKKRVSRRSIFEMYEPSELESSHLT 283
E E E ++ E E+E E+EG +K + E E ES
Sbjct: 1880 EGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAE 1939
Query: 284 DQDNEIRATDLPERFQLRSIPVKGAEDDELEEEA 317
Q+ E A + + Q S + E E EEEA
Sbjct: 1940 AQEAEEAAQEAEGQTQPESEVI---ESQEAEEEA 1970
Score = 38.1 bits (87), Expect = 0.075
Identities = 47/217 (21%), Positives = 87/217 (40%), Gaps = 16/217 (7%)
Query: 37 DEEEEEENLDDQDEQGNLKGFINDDDDEDEGEEDEGSDSGDSEDDVGHK-KRKRTSFDDR 95
+ E+E E + ++ E G G + +D +GE G D + D + + +
Sbjct: 1789 EAEQEGEGISERGETG---GQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQ 1845
Query: 96 LEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEG 155
E + + E + G+ + + E + E + E+ E E+ + EG
Sbjct: 1846 PESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEG 1905
Query: 156 EEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLKKPKWRKKLPGYT--DAALQEA 213
E EA + A PE E + E++ +D + + + + ++ G T ++ + E+
Sbjct: 1906 AEAPEAEKE--AQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIES 1963
Query: 214 QEIFGVDFDYDEFEKYNEYDEELEEEYEYEDDEAEGE 250
QE E E E ++ E E E EAEGE
Sbjct: 1964 QEA--------EEEAQPESEDVEALEVEVETQEAEGE 1992
Score = 32.3 bits (72), Expect = 4.1
Identities = 28/116 (24%), Positives = 52/116 (44%), Gaps = 24/116 (20%)
Query: 5 VESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDE-------------- 50
V+ E ++EE +EG V TK E E + ++EEE L++ +E
Sbjct: 1320 VQLEETKTEEGLQEEG-VQLEETK---ETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLE 1375
Query: 51 ------QGNLKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDD 100
+G L+G ++ ++EG +EGS G + K + DD +++++
Sbjct: 1376 EVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEE 1431
Score = 32.0 bits (71), Expect = 5.3
Identities = 42/178 (23%), Positives = 79/178 (44%), Gaps = 32/178 (17%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEE--ENLDDQDEQGNLKGFINDDDD 63
E EAE EE + ++ + V+EE EE +E E Q+E L ++
Sbjct: 1273 EDEAERDSEEQRASSNL-EQLAENTVQEEVQLEETKEGTEGEGLQEEAVQL-----EETK 1326
Query: 64 EDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKK 123
+EG ++EG ++++ G +++ + + +E+ + ++E GV++
Sbjct: 1327 TEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEE-GVQL----------- 1374
Query: 124 MSDDEDDDEEEYGKEEH-EKEAIAEEIFQDGEGEEG----QEAMEAPMAPPEEEEEDD 176
+E + G E + EA+ E + ++G EEG QE EA + +EDD
Sbjct: 1375 -------EEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDD 1425
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 56.6 bits (135), Expect = 2e-07
Identities = 54/200 (27%), Positives = 89/200 (44%), Gaps = 28/200 (14%)
Query: 9 AEESEEEYNDEGEVVPRVT---KKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDED 65
AEE+EEE+ +V+ + ++ ++++D DE+EEE+ + + L+ I+D +D+
Sbjct: 157 AEEAEEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELR--IHDLEDDL 214
Query: 66 EGEEDEGSDSGDSEDDV------------GHKKRKRTSFDDRL----EDDDFDLIEENL- 108
E D SG+ V G KK+K+ DD +D DF+ E +
Sbjct: 215 EMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYM 274
Query: 109 --GVKVKRGQKYRRVKKMSDDEDD---DEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAME 163
G + + + K +E DE+ EE E+E EE ++ E ++ E
Sbjct: 275 SDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQE 334
Query: 164 APMAPPEEEEED-DEESDID 182
EE D EESDID
Sbjct: 335 KKRRKDSSEESDSSEESDID 354
Score = 45.4 bits (106), Expect = 5e-04
Identities = 51/198 (25%), Positives = 76/198 (38%), Gaps = 49/198 (24%)
Query: 119 RRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGE---------GEEGQEAMEAPMAPP 169
RR+K DED++E+E E ++ D E GEEG +A P
Sbjct: 180 RRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAP 239
Query: 170 ---------------EEEEEDDEESDID----DFIVDDDGQPLKKPKWRKKLPGYTDAAL 210
+E ED ++ D + D++ D ++P+ + K P
Sbjct: 240 LAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAP------- 292
Query: 211 QEAQEIFGVDFDYDEFEKYNEYDEELEEEYEYEDDEAEGEIRVRPKKTTKKRVSRRSIFE 270
Q+ + GVD D EE EEE E+D+ E E + P KKR S
Sbjct: 293 QQEEGPKGVDEQSDS-------SEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSS--- 342
Query: 271 MYEPSELESSHLTDQDNE 288
E +SS +D D+E
Sbjct: 343 ----EESDSSEESDIDSE 356
Score = 33.9 bits (76), Expect = 1.4
Identities = 38/171 (22%), Positives = 67/171 (39%), Gaps = 13/171 (7%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDED 65
+ EA E ++ + EG+ V ++ EE E + Q E+G KG D +
Sbjct: 254 DDEAFEDSDDGDFEGQEVDYMSDG---SSSSQEEPESKAKAPQQEEGP-KGVDEQSDSSE 309
Query: 66 EGEEDEGSDSGDSEDDVG------HKKRKRTSFD--DRLEDDDFDLIEENLGVKVKRGQK 117
E EE++ + E++ KKR++ S + D E+ D D + K+
Sbjct: 310 ESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTP 369
Query: 118 YRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEI-FQDGEGEEGQEAMEAPMA 167
+R +K S G E + + + + E+G+ E P A
Sbjct: 370 PKRERKPSGGSSRGNSRPGTPSAEGGSTSSTLRAAASKLEQGKRVSEMPAA 420
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 56.2 bits (134), Expect = 3e-07
Identities = 53/189 (28%), Positives = 85/189 (44%), Gaps = 48/189 (25%)
Query: 5 VESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDE 64
++SE EE EEE +E EEE+ + EEEEE ++++E+G + E
Sbjct: 401 LKSEGEEEEEEEEEE------------EEEEGEGEEEEEEGEEEEEEGG--------EGE 440
Query: 65 DEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKM 124
+ GEE+E + GD + D ++ + +S + LE +D+ GV V+ G +
Sbjct: 441 ELGEEEEVEEEGDVDSDEEEEEDEESS-SEGLEAEDWAQ-----GV-VEAGGSFGA---- 489
Query: 125 SDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDF 184
YG +E E + + GE + E ++EEEDDE+ D DD
Sbjct: 490 ----------YGAQE-EAQCPTLHFLEGGEDSDSDSEEE------DDEEEDDEDEDDDDD 532
Query: 185 IVDDDGQPL 193
D D P+
Sbjct: 533 EEDGDEVPV 541
Score = 55.1 bits (131), Expect = 6e-07
Identities = 38/128 (29%), Positives = 63/128 (49%), Gaps = 3/128 (2%)
Query: 126 DDEDDDEEEYGKEEHEKEAIAEEIFQDGEGE---EGQEAMEAPMAPPEEEEEDDEESDID 182
++E+++EEE G+ E E+E EE + GEGE E +E E +EEEE+DEES +
Sbjct: 410 EEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSE 469
Query: 183 DFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEY 242
+D Q + + G + A D D + + +EE +E+ +
Sbjct: 470 GLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDD 529
Query: 243 EDDEAEGE 250
+DDE +G+
Sbjct: 530 DDDEEDGD 537
Score = 53.1 bits (126), Expect = 2e-06
Identities = 44/178 (24%), Positives = 72/178 (40%), Gaps = 50/178 (28%)
Query: 24 PRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDEDEGEEDEGSDSGDSEDDVG 83
P T + + +EEEEEE ++++E+EGE +E + G+ E++ G
Sbjct: 393 PNATITTSLKSEGEEEEEEE----------------EEEEEEEGEGEEEEEEGEEEEEEG 436
Query: 84 HKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDEDDDEEEYGKEEHEKE 143
+ + ++ E+ D D SD+E++++EE E E E
Sbjct: 437 GEGEELGEEEEVEEEGDVD----------------------SDEEEEEDEESSSEGLEAE 474
Query: 144 AIAEEIFQDGEGEEGQEAMEAPMAP------------PEEEEEDDEESDIDDFIVDDD 189
A+ + + G A E P + EEEDDEE D +D DDD
Sbjct: 475 DWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDD 532
Score = 42.7 bits (99), Expect = 0.003
Identities = 25/68 (36%), Positives = 38/68 (55%), Gaps = 10/68 (14%)
Query: 32 EEEDDDEEEEEENLDDQDEQGNLKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTS 91
+ + D EEE++E DD+DE +DDDDE++G+E G++ KR TS
Sbjct: 509 DSDSDSEEEDDEEEDDEDE--------DDDDDEEDGDEVPVPSFGEAMAYFAMVKRYLTS 560
Query: 92 F--DDRLE 97
F DDR++
Sbjct: 561 FPIDDRVQ 568
>gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]
Length = 681
Score = 55.8 bits (133), Expect = 3e-07
Identities = 78/302 (25%), Positives = 129/302 (42%), Gaps = 46/302 (15%)
Query: 38 EEEEEENLDDQDEQGNLKGFINDDDDED--EGEEDEGSDSGDSEDDVGHKK--------R 87
E EE+E +D E I DD ED + EE+E SD G+ + ++G + R
Sbjct: 109 ESEEQEREEDGSE-------IEADDKEDLEDLEEEEVSDMGNDDPEMGERAENSSKSDLR 161
Query: 88 KRTSFDDRLEDDDFDLIEENLGVKVK-RGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIA 146
K F D D DFD+ + KV+ +GQ R K + DD+ + E EA
Sbjct: 162 KSPVFSDEDSDLDFDISKLEQQSKVQNKGQGKPREKSIVDDK-------FFKLSEMEAYL 214
Query: 147 EEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFIVDDDG-----QPLKKPKWRKK 201
E I ++ E ++ + EEEE+ D DID +D+G + LK K +
Sbjct: 215 ENIEKEEERKDDND---------EEEEDIDFFEDIDS--DEDEGGLFGSKKLKSGKSSRN 263
Query: 202 LPGYTD--AALQEAQEIFGV-DFDYDEFEKYNEYDEELEEEYEYEDDEAEGEIRVRPKKT 258
L Y D ++ ++I V D + D ++ +E EE EE + + + +++
Sbjct: 264 LK-YKDFFDPVESDEDITNVHDDELDSNKEDDEIAEEEAEELSISETDEDDDLQENEDNK 322
Query: 259 TKKRVSRRSIFEMYEPSELESSH-LTDQDNEIRATDLPERFQLRSIPVKGAEDDELEEEA 317
K +R F + + +E E + L + N E+ Q + + + EL E+
Sbjct: 323 QHKESLKRVTFALPDDAETEDTGVLNVKKNSDEVKSSFEKRQEKMNEKIASLEKELLEKK 382
Query: 318 DW 319
W
Sbjct: 383 PW 384
Score = 43.1 bits (100), Expect = 0.002
Identities = 75/326 (23%), Positives = 132/326 (40%), Gaps = 50/326 (15%)
Query: 3 DFVESEAEESEEEYNDEGEVVPR----VTKKFVEEED-----DDEEEEEENLDDQDEQGN 53
DF S+ E+ + N +G+ PR V KF + + ++ E+EEE DD DE+
Sbjct: 174 DFDISKLEQQSKVQN-KGQGKPREKSIVDDKFFKLSEMEAYLENIEKEEERKDDNDEEEE 232
Query: 54 LKGFIND-DDDEDEGE--EDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDD------FDLI 104
F D D DEDEG + SG S ++ +K F D +E D+ D +
Sbjct: 233 DIDFFEDIDSDEDEGGLFGSKKLKSGKSSRNLKYK-----DFFDPVESDEDITNVHDDEL 287
Query: 105 EENLGVKVKRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIF---QDGEGEEGQEA 161
+ N ++ + DEDDD +E + KE++ F D E E+
Sbjct: 288 DSNKEDDEIAEEEAEELSISETDEDDDLQENEDNKQHKESLKRVTFALPDDAETEDTGVL 347
Query: 162 MEAPMAPPEEEEEDDEESDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDF 221
+ + + + +++ I + + L+K W +L G A + +
Sbjct: 348 NVKKNSDEVKSSFEKRQEKMNEKIASLEKELLEKKPW--QLQGEVTAQKRPENSLLEETL 405
Query: 222 DYDEFEKYNEYDEELEEEYEYED-------DEAEGEI--RVRPKKTT---KKRV------ 263
+D + E E + ED D+A ++ + +PK+ KKR+
Sbjct: 406 HFDHAVRMAPVITE-ETTLQLEDIIKQRIRDQAWDDVVRKEKPKEDAYEYKKRLTLDHEK 464
Query: 264 SRRSIFEMYEPS--ELESSHLTDQDN 287
S+ S+ E+YE +L +++N
Sbjct: 465 SKLSLAEIYEQEYIKLNQQKTAEEEN 490
Score = 31.6 bits (70), Expect = 7.0
Identities = 43/212 (20%), Positives = 87/212 (41%), Gaps = 30/212 (14%)
Query: 763 QVEEDDDFMDENQGKGIRVLGIAFSSARDHPVFCALVNGEGEVTDFLRLPHFTKRRTAWR 822
+ +EDDD + K + F + E E T L + + +
Sbjct: 308 ETDEDDDLQENEDNK-------QHKESLKRVTFALPDDAETEDTGVLNVKKNSDEVKSSF 360
Query: 823 EEEREKKAQDIETLKKFLLNKKPHVV--TVAGENRDAQMLIEDVKRIVHEL--------D 872
E+ +EK + I +L+K LL KKP + V + R L+E+ H + +
Sbjct: 361 EKRQEKMNEKIASLEKELLEKKPWQLQGEVTAQKRPENSLLEETLHFDHAVRMAPVITEE 420
Query: 873 QGQQLSSIGVELVDNELAILYMNSKKSEAEFRDYPPVL-----RQAVSLARRIQDPLIEF 927
QL I + + ++ + +K + + +Y L + +SLA + I+
Sbjct: 421 TTLQLEDIIKQRIRDQAWDDVVRKEKPKEDAYEYKKRLTLDHEKSKLSLAEIYEQEYIKL 480
Query: 928 AQVCSSDEDILCLKFHPLQEHVVKEELLNALY 959
Q +++E+ +P EHV ++++++L+
Sbjct: 481 NQQKTAEEE------NP--EHVEIQKMMDSLF 504
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 55.8 bits (133), Expect = 3e-07
Identities = 43/169 (25%), Positives = 83/169 (49%), Gaps = 15/169 (8%)
Query: 10 EESEEEYNDEGEVVPRVTKKFVEEEDDDEE---EEEENLDDQDEQGNLKGFINDDDDEDE 66
E+ +E+ DEGE + +E+++DEE EEEE ++++DE + G +D++E+E
Sbjct: 97 EDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEE 156
Query: 67 GEEDEGSDSGDSEDDVGHKKRKRTSFDDRLED---DDFDLIEE-------NLGVKVKRGQ 116
EE+E + ++ED + R D +D D++D +E NLG K+
Sbjct: 157 EEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLG-KIAEDA 215
Query: 117 KYR-RVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEA 164
YR R + + + E +++E E+ D + + +E +++
Sbjct: 216 AYRARTESEMNSNTSNSLEDDSDKNENLGRKSELSLDLDSDVVRETVDS 264
Score = 51.6 bits (122), Expect = 7e-06
Identities = 30/121 (24%), Positives = 58/121 (47%), Gaps = 20/121 (16%)
Query: 37 DEEEEEENLDDQDEQGNLKGFINDDDDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRL 96
DE ++ + +D DE+ +G +D+++ G+EDE + GD E++ ++
Sbjct: 88 DECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEE--------EEIEEED 139
Query: 97 EDDDFDLIEENLGVKVKRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGE 156
EDDD D G+ ++ ++E+++EEE E+H+ I QD E +
Sbjct: 140 EDDDED------------GEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKD 187
Query: 157 E 157
+
Sbjct: 188 D 188
Score = 46.6 bits (109), Expect = 2e-04
Identities = 32/123 (26%), Positives = 57/123 (46%), Gaps = 22/123 (17%)
Query: 62 DDEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRV 121
+D DE EEDEG + + D+ G D+ ED++ D EE +
Sbjct: 97 EDMDEKEEDEGEEYSEDNDEPG---------DEDEEDEEGDREEEE------------EI 135
Query: 122 KKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDI 181
++ +D+D+D E+ EE E+E EE ++ E E+ Q + E++D+ +
Sbjct: 136 EEEDEDDDEDGEDVEDEEEEEEE-EEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEY 194
Query: 182 DDF 184
D++
Sbjct: 195 DNY 197
Score = 44.7 bits (104), Expect = 8e-04
Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 2/84 (2%)
Query: 97 EDDDFDLIEENLGVKVKRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGE 156
E DD D E+ + G++Y DED+++EE +EE E+ I EE D E
Sbjct: 89 ECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEE--IEEEDEDDDEDG 146
Query: 157 EGQEAMEAPMAPPEEEEEDDEESD 180
E E E EEEEE++E D
Sbjct: 147 EDVEDEEEEEEEEEEEEEEEENED 170
Score = 43.1 bits (100), Expect = 0.002
Identities = 42/148 (28%), Positives = 61/148 (41%), Gaps = 40/148 (27%)
Query: 126 DDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDFI 185
DD D E+ KEE E E +E+ D G+E +E E EEEE+ EE D DD
Sbjct: 91 DDSDGTEDMDEKEEDEGEEYSED--NDEPGDEDEEDEEGD----REEEEEIEEEDEDD-- 142
Query: 186 VDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEYEYEDD 245
D+DG+ D ++ E+ E +EE EEE E ED
Sbjct: 143 -DEDGE------------------------------DVEDEEEEEEEEEEEEEEEENEDH 171
Query: 246 EAEGEIRVRPKKTTKKRVSRRSIFEMYE 273
+ R + T+K + ++ Y+
Sbjct: 172 QMNCH-NTRIMQDTEKDDNNNDEYDNYD 198
Score = 42.0 bits (97), Expect = 0.005
Identities = 28/101 (27%), Positives = 51/101 (50%), Gaps = 9/101 (8%)
Query: 88 KRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDED-----DDEEEYGKEEHEK 142
KR F + + D +++ G + ++ ++ S+D D D+E+E G E E+
Sbjct: 74 KRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEE 133
Query: 143 EAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDD 183
E E+ D +GE+ ++ E EEEEE++EE + +D
Sbjct: 134 EIEEEDEDDDEDGEDVEDEEE----EEEEEEEEEEEEENED 170
Score = 38.5 bits (88), Expect = 0.057
Identities = 28/112 (25%), Positives = 53/112 (47%), Gaps = 10/112 (8%)
Query: 125 SDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESDIDDF 184
++D D+ EE+ G+E E D G+E +E E EE EE+DE+ D D
Sbjct: 96 TEDMDEKEEDEGEEYSED--------NDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGE 147
Query: 185 IVDDDGQPLKKPKWRKKLPGYTDAAL--QEAQEIFGVDFDYDEFEKYNEYDE 234
V+D+ + ++ + ++ D + + + + D + ++Y+ YDE
Sbjct: 148 DVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199
Score = 37.4 bits (85), Expect = 0.13
Identities = 36/130 (27%), Positives = 52/130 (40%), Gaps = 40/130 (30%)
Query: 121 VKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEESD 180
VK S D+ ++ G E+ +++ ++ EGEE E + P EE+EE D E
Sbjct: 80 VKADSSSVDECDDSDGTEDMDEK-------EEDEGEEYSEDNDEPGDEDEEDEEGDRE-- 130
Query: 181 IDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEEEY 240
E +EI D D DE + E +EE EEE
Sbjct: 131 -------------------------------EEEEIEEEDEDDDEDGEDVEDEEEEEEEE 159
Query: 241 EYEDDEAEGE 250
E E++E E E
Sbjct: 160 EEEEEEEENE 169
>gi|19923844 coiled-coil domain containing 82 [Homo sapiens]
Length = 544
Score = 55.8 bits (133), Expect = 3e-07
Identities = 60/238 (25%), Positives = 99/238 (41%), Gaps = 48/238 (20%)
Query: 34 EDDDEEEEEENLDDQDEQGNLKGFIND---------DDDEDEGEEDEGSDSGD------- 77
E++ + + N+D QD++ +L ND +DD+++ E +D
Sbjct: 110 EEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIE 169
Query: 78 ---SEDDVGHKKRKRTS--FDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDEDDDE 132
E+D+ KRKR S D E DD D++ +GVK R + ++ E
Sbjct: 170 DDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPE 229
Query: 133 EEYGKEEHEKEAIAEEI--------------FQDGEGEEGQEAMEAPMAPPEEEEEDDEE 178
+ ++ EK +E+ F+D E E + E EEEEED+ E
Sbjct: 230 KTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEV----DEEEEEDNYE 285
Query: 179 SD-------IDDFIV-DDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEK 228
SD IDDF+V D++G K + +KL + L + ++ Y FE+
Sbjct: 286 SDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLT-TSQLKLVKQNSLYSFSDHYTHFER 342
Score = 44.7 bits (104), Expect = 8e-04
Identities = 63/265 (23%), Positives = 111/265 (41%), Gaps = 68/265 (25%)
Query: 35 DDDEEEEEENLDDQDEQGNLKGFINDDD-DEDEGE-----------------EDEGSDS- 75
D DEE + E D +E + + F ND++ D ++G + EG+DS
Sbjct: 39 DSDEELDSEEFDSDEELDSDESFENDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSK 98
Query: 76 -------GDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDE 128
G + ++ +K + R + L+D + L +E+ + + GQ E
Sbjct: 99 CLINSGNGSTYEEETNKIKHR---NIDLQDQEKHLSQEDNDLNKQTGQII---------E 146
Query: 129 DDDEEEYGKEEHEKEAIAEEIFQDG-EGEEGQEAMEAPMAPPEEEEEDDEESDI------ 181
DD E+ +E+++ +I +D E E+ + ++ + ++ ++SDI
Sbjct: 147 DDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVG 206
Query: 182 ---DDFIVDDDGQPLKKPKWRKKLPGYTDAA-----LQEAQEI----------FGVDFDY 223
+V+D+G + + +K P T AA LQ+ +E+ G DF+
Sbjct: 207 VKRPRRVVEDEGSSV---EMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFED 263
Query: 224 DEFEKYNEYDE--ELEEEYEYEDDE 246
E E DE E EEE YE DE
Sbjct: 264 SEKESCPSSDEVDEEEEEDNYESDE 288
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 55.5 bits (132), Expect = 5e-07
Identities = 67/326 (20%), Positives = 150/326 (46%), Gaps = 28/326 (8%)
Query: 10 EESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDD----ED 65
++ EE+ + E + +K E+E E+EE+ +++ + I + +D ++
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
Query: 66 EGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVK---VKRGQK-YRRV 121
E ++ + E+ + ++ K D+++++ + ++ + ++ KR +K +R+
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Query: 122 KKMSDDED---DDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEE 178
KKM + ++ + EEE ++E EK EE+ QD EE +E M +EEEE +E
Sbjct: 413 KKMREQDEKIREQEEEMWRQE-EKIRELEEMMQD--QEEKLREVEEKM---QEEEEKMQE 466
Query: 179 SDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEE 238
+ ++ Q ++ WR++ + + E +E + + EK E +E+++E
Sbjct: 467 QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM-----WRQEEKMWEQEEKMQE 521
Query: 239 EYE----YEDDEAEGEIRV--RPKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEIRAT 292
+ E E+ E E+R+ + +K ++ V + + E ++ L E +
Sbjct: 522 QEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQ 581
Query: 293 DLPERFQLRSIPVKGAEDDELEEEAD 318
LP + + +K E L+++ D
Sbjct: 582 RLPTLTPILQVELKSQEAQSLQQQQD 607
Score = 34.7 bits (78), Expect = 0.83
Identities = 34/180 (18%), Positives = 81/180 (45%), Gaps = 19/180 (10%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDED 65
E + E EE D+ E + V +K EEE+ +E+EE+ + Q+E+ I + +++
Sbjct: 433 EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEK-IQRQEEK------IQEQEEKT 485
Query: 66 EGEE---DEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVK 122
+E + + E+ + ++ K ++++++ + + + ++ + + +++ +
Sbjct: 486 WRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEE 545
Query: 123 KMSDDE---DDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEES 179
KM + E + EE GK + E + G G E + P + E +E+
Sbjct: 546 KMQEQEVRLQELEERLGKLGQKAELLG------GAGRESGSQRLPTLTPILQVELKSQEA 599
Score = 31.2 bits (69), Expect = 9.1
Identities = 27/122 (22%), Positives = 62/122 (50%), Gaps = 16/122 (13%)
Query: 5 VESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEE-----EENLDDQDEQGNLKGFIN 59
VE + +E EE+ ++ E + R +K E+E+ +E EE + +Q+E K +
Sbjct: 453 VEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE----KMWRQ 508
Query: 60 DDD--DEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDL--IEENLGVKVKRG 115
++ +++E +++ E+ + ++ + ++++++ + L +EE LG K G
Sbjct: 509 EEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLG---KLG 565
Query: 116 QK 117
QK
Sbjct: 566 QK 567
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 55.5 bits (132), Expect = 5e-07
Identities = 67/326 (20%), Positives = 150/326 (46%), Gaps = 28/326 (8%)
Query: 10 EESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDD----ED 65
++ EE+ + E + +K E+E E+EE+ +++ + I + +D ++
Sbjct: 293 QQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE 352
Query: 66 EGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVK---VKRGQK-YRRV 121
E ++ + E+ + ++ K D+++++ + ++ + ++ KR +K +R+
Sbjct: 353 EKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQE 412
Query: 122 KKMSDDED---DDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEE 178
KKM + ++ + EEE ++E EK EE+ QD EE +E M +EEEE +E
Sbjct: 413 KKMREQDEKIREQEEEMWRQE-EKIRELEEMMQD--QEEKLREVEEKM---QEEEEKMQE 466
Query: 179 SDIDDFIVDDDGQPLKKPKWRKKLPGYTDAALQEAQEIFGVDFDYDEFEKYNEYDEELEE 238
+ ++ Q ++ WR++ + + E +E + + EK E +E+++E
Sbjct: 467 QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKM-----WRQEEKMWEQEEKMQE 521
Query: 239 EYE----YEDDEAEGEIRV--RPKKTTKKRVSRRSIFEMYEPSELESSHLTDQDNEIRAT 292
+ E E+ E E+R+ + +K ++ V + + E ++ L E +
Sbjct: 522 QEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQ 581
Query: 293 DLPERFQLRSIPVKGAEDDELEEEAD 318
LP + + +K E L+++ D
Sbjct: 582 RLPTLTPILQVELKSQEAQSLQQQQD 607
Score = 34.7 bits (78), Expect = 0.83
Identities = 34/180 (18%), Positives = 81/180 (45%), Gaps = 19/180 (10%)
Query: 6 ESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGFINDDDDED 65
E + E EE D+ E + V +K EEE+ +E+EE+ + Q+E+ I + +++
Sbjct: 433 EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEK-IQRQEEK------IQEQEEKT 485
Query: 66 EGEE---DEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDLIEENLGVKVKRGQKYRRVK 122
+E + + E+ + ++ K ++++++ + + + ++ + + +++ +
Sbjct: 486 WRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEE 545
Query: 123 KMSDDE---DDDEEEYGKEEHEKEAIAEEIFQDGEGEEGQEAMEAPMAPPEEEEEDDEES 179
KM + E + EE GK + E + G G E + P + E +E+
Sbjct: 546 KMQEQEVRLQELEERLGKLGQKAELLG------GAGRESGSQRLPTLTPILQVELKSQEA 599
Score = 31.2 bits (69), Expect = 9.1
Identities = 27/122 (22%), Positives = 62/122 (50%), Gaps = 16/122 (13%)
Query: 5 VESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEE-----EENLDDQDEQGNLKGFIN 59
VE + +E EE+ ++ E + R +K E+E+ +E EE + +Q+E K +
Sbjct: 453 VEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEE----KMWRQ 508
Query: 60 DDD--DEDEGEEDEGSDSGDSEDDVGHKKRKRTSFDDRLEDDDFDL--IEENLGVKVKRG 115
++ +++E +++ E+ + ++ + ++++++ + L +EE LG K G
Sbjct: 509 EEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLG---KLG 565
Query: 116 QK 117
QK
Sbjct: 566 QK 567
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,351,490
Number of Sequences: 37866
Number of extensions: 3739845
Number of successful extensions: 47326
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 365
Number of HSP's successfully gapped in prelim test: 750
Number of HSP's that attempted gapping in prelim test: 19939
Number of HSP's gapped (non-prelim): 13875
length of query: 1726
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1610
effective length of database: 13,855,062
effective search space: 22306649820
effective search space used: 22306649820
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.