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Search of human proteins with 27477111
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27477111 step II splicing factor SLU7 [Homo sapiens]
(586 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27477111 step II splicing factor SLU7 [Homo sapiens] 1212 0.0
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 50 8e-06
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 49 2e-05
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 48 2e-05
gi|148746195 trichohyalin [Homo sapiens] 48 2e-05
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 47 4e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 47 6e-05
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 47 6e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 46 8e-05
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 45 1e-04
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 45 2e-04
gi|239752449 PREDICTED: hypothetical protein [Homo sapiens] 45 2e-04
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ... 44 5e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 44 5e-04
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 44 5e-04
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa... 44 5e-04
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa... 44 5e-04
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa... 44 5e-04
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa... 44 5e-04
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 44 5e-04
gi|168229156 NFKB activating protein [Homo sapiens] 42 0.001
gi|8923271 coiled-coil domain containing 49 [Homo sapiens] 42 0.001
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 42 0.002
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 42 0.002
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 42 0.002
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap... 42 0.002
gi|18426913 drebrin 1 isoform b [Homo sapiens] 42 0.002
gi|18426915 drebrin 1 isoform a [Homo sapiens] 42 0.002
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 42 0.002
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 42 0.002
>gi|27477111 step II splicing factor SLU7 [Homo sapiens]
Length = 586
Score = 1212 bits (3135), Expect = 0.0
Identities = 586/586 (100%), Positives = 586/586 (100%)
Query: 1 MSATVVDAVNAAPLSGSKEMSLEEPKKMTREDWRKKKELEEQRKLGNAPAEVDEEGKDIN 60
MSATVVDAVNAAPLSGSKEMSLEEPKKMTREDWRKKKELEEQRKLGNAPAEVDEEGKDIN
Sbjct: 1 MSATVVDAVNAAPLSGSKEMSLEEPKKMTREDWRKKKELEEQRKLGNAPAEVDEEGKDIN 60
Query: 61 PHIPQYISSVPWYIDPSKRPTLKHQRPQPEKQKQFSSSGEWYKRGVKENSIITKYRKGAC 120
PHIPQYISSVPWYIDPSKRPTLKHQRPQPEKQKQFSSSGEWYKRGVKENSIITKYRKGAC
Sbjct: 61 PHIPQYISSVPWYIDPSKRPTLKHQRPQPEKQKQFSSSGEWYKRGVKENSIITKYRKGAC 120
Query: 121 ENCGAMTHKKKDCFERPRRVGAKFTGTNIAPDEHVQPQLMFDYDGKRDRWNGYNPEEHMK 180
ENCGAMTHKKKDCFERPRRVGAKFTGTNIAPDEHVQPQLMFDYDGKRDRWNGYNPEEHMK
Sbjct: 121 ENCGAMTHKKKDCFERPRRVGAKFTGTNIAPDEHVQPQLMFDYDGKRDRWNGYNPEEHMK 180
Query: 181 IVEEYAKVDLAKRTLKAQKLQEELASGKLVEQANSPKHQWGEEEPNSQMEKDHNSEDEDE 240
IVEEYAKVDLAKRTLKAQKLQEELASGKLVEQANSPKHQWGEEEPNSQMEKDHNSEDEDE
Sbjct: 181 IVEEYAKVDLAKRTLKAQKLQEELASGKLVEQANSPKHQWGEEEPNSQMEKDHNSEDEDE 240
Query: 241 DKYADDIDMPGQNFDSKRRITVRNLRIREDIAKYLRNLDPNSAYYDPKTRAMRENPYANA 300
DKYADDIDMPGQNFDSKRRITVRNLRIREDIAKYLRNLDPNSAYYDPKTRAMRENPYANA
Sbjct: 241 DKYADDIDMPGQNFDSKRRITVRNLRIREDIAKYLRNLDPNSAYYDPKTRAMRENPYANA 300
Query: 301 GKNPDEVSYAGDNFVRYTGDTISMAQTQLFAWEAYDKGSEVHLQADPTKLELLYKSFKVK 360
GKNPDEVSYAGDNFVRYTGDTISMAQTQLFAWEAYDKGSEVHLQADPTKLELLYKSFKVK
Sbjct: 301 GKNPDEVSYAGDNFVRYTGDTISMAQTQLFAWEAYDKGSEVHLQADPTKLELLYKSFKVK 360
Query: 361 KEDFKEQQKESILEKYGGQEHLDAPPAELLLAQTEDYVEYSRHGTVIKGQERAVACSKYE 420
KEDFKEQQKESILEKYGGQEHLDAPPAELLLAQTEDYVEYSRHGTVIKGQERAVACSKYE
Sbjct: 361 KEDFKEQQKESILEKYGGQEHLDAPPAELLLAQTEDYVEYSRHGTVIKGQERAVACSKYE 420
Query: 421 EDVKIHNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAGKEIVNSEECIINEITGEESV 480
EDVKIHNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAGKEIVNSEECIINEITGEESV
Sbjct: 421 EDVKIHNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAGKEIVNSEECIINEITGEESV 480
Query: 481 KKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVK 540
KKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVK
Sbjct: 481 KKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVK 540
Query: 541 ETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDPMASFLGQ 586
ETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDPMASFLGQ
Sbjct: 541 ETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDPMASFLGQ 586
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 49.7 bits (117), Expect = 8e-06
Identities = 82/413 (19%), Positives = 164/413 (39%), Gaps = 71/413 (17%)
Query: 176 EEHMKIVEEYAKVDLAKRTLKAQKLQEELAS-GKLVEQANSPKHQWGEEEP-----NSQM 229
E + + E K++ AK L Q+LQ E GK ++ ++ EE N Q
Sbjct: 239 EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 298
Query: 230 EKDHNSEDEDEDKYADDIDMPGQNFDSKRRITVRNLRIREDIAKYLRNLDPNSAYYDPKT 289
E+ ++E ++ + I + + +I + +IRE K +R + + K
Sbjct: 299 EEKMWRQEEKIQEWEEKIQ------EQEEKIREQEEKIREQEEK-MRRQEEMMWEKEEKM 351
Query: 290 RAMRENPYANAGKNPDEVSYAGDNFVRYTGDTISMAQTQLFAWEAYDKGSEVHLQADPTK 349
R E + K M + + WE +K E+
Sbjct: 352 RRQEEMMWEKEEK---------------------MRRLEEMMWEKEEKIRELE------- 383
Query: 350 LELLYKSFKVKKEDFKEQQKESILEKYGGQEHLDAP--PAELLLAQTEDYVEYSRHGTVI 407
E +++ K+++++ K Q++E I E+ QE E + Q E E + +
Sbjct: 384 -EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK--MW 440
Query: 408 KGQERAVACSKYEEDVKIHNHTHIWGSYWK----EGRWGYKCCHSFFKYSYCTGEAGKEI 463
+ +E+ K E+ K +W K E W K E
Sbjct: 441 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK-----------------EK 483
Query: 464 VNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHE 523
++ +E I + EE V + + M +EK++E+++K ++++K R+ ++E+K
Sbjct: 484 MHEQEKIRKQ---EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR 540
Query: 524 KLKKALNAEEARLLHVKETMQIDER-KRPYNSMYETREPTEEEMEAYRMKRQR 575
+ ++ + +E ++ +E MQ E+ +R + E E E+ E R + ++
Sbjct: 541 EQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEK 593
Score = 41.2 bits (95), Expect = 0.003
Identities = 77/423 (18%), Positives = 170/423 (40%), Gaps = 60/423 (14%)
Query: 166 KRDRWNGYNPEEHMKIVEEYAKVDLAKRTLKAQKLQEELASGKLVEQANSPKHQWGEEEP 225
+ + WN N ++ K+ + K+ Q+ +E K+ EQ + Q EE+
Sbjct: 287 ENELWNRLNQQQEEKMWRQEEKI---------QEWEE-----KIQEQEEKIREQ--EEKI 330
Query: 226 NSQMEKDHNSED---EDEDKYADDIDMPGQNFDSKRRITVRNLRIREDIAKYLRNLDPNS 282
Q EK E+ E E+K +M + + RR+ E I + +
Sbjct: 331 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQE 390
Query: 283 AYYDPKTRAMRENPYANAGKNPDEVS--YAGDNFVRYTGDTISMAQTQLFAWEAYDKGSE 340
+ + + E K ++ + + + +R + I + +++ E
Sbjct: 391 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE------- 443
Query: 341 VHLQADPTKLELLYKSFKVKKEDFKEQQKESILEKYGGQEHLDAPPAELLLAQTEDYVEY 400
E +++ K+++E+ +++Q+E ++ +E E + Q E E
Sbjct: 444 ----------EKIHEQEKIREEEKRQEQEEMWRQEEKIREQ------EEIWRQKEKMHEQ 487
Query: 401 SRHGTVIKGQERAVACSKYEEDVKIHNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAG 460
+ I+ QE V + ++ K+H+ +E W + + E
Sbjct: 488 EK----IRKQEEKV----WRQEEKMHDQEEKIREQ-EEKMWRQE--EKIREQEEKIREQE 536
Query: 461 KEIVNSEECIIN--EITGEESVK-KPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDD 517
++I EE + E GE+ K + Q M +EK++E+++K +++K+K R+ +
Sbjct: 537 EKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWE 596
Query: 518 EEKKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPD 577
+E+K + ++ + +E ++ +E M E K E EE+M ++ ++ +
Sbjct: 597 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK--MQEQEEKMRRQEEKMWEQEVRLRQQE 654
Query: 578 DPM 580
+ M
Sbjct: 655 EKM 657
Score = 35.8 bits (81), Expect = 0.11
Identities = 72/415 (17%), Positives = 158/415 (38%), Gaps = 80/415 (19%)
Query: 156 QPQLMFDYDGKRDRWNGYNPEEHMKIVEEYAKVDLAKRTLKAQ-----------KLQEEL 204
Q + M+ + K W E+ KI E+ K+ + ++ Q + QEE+
Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEM 357
Query: 205 ASGKLVEQANSPKHQWGEEEPNSQMEKDHNSED---EDEDKYADDIDMPGQN-------- 253
K + + W +EE ++E+ + ++ E E+K ++ + Q
Sbjct: 358 MWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 417
Query: 254 -FDSKRRITVRNLRIREDIAKYLRN---LDPNSAYYDPKTRAMRENPYANAGKNPDEVSY 309
+ + +I + +IRE K R + + + R +E + K ++
Sbjct: 418 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 477
Query: 310 AGDNFVRYTGDTISMAQTQLFAWEAYDKGSEVHLQADPTKLELLYKSFKVKKEDFKEQQK 369
+ + I + +++ E E ++ K+ + + ++E +EQ+
Sbjct: 478 WRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQE- 536
Query: 370 ESILEKYGGQEHLDAPPAELLLAQTEDYVEYSRHGTVIKGQERAVACSKYEEDVKIHNHT 429
EK QE + E + Q E E + ++ QE + E++ KI
Sbjct: 537 ----EKIREQEEMMQEQEEKMGEQEEKMQEQEK----MRRQEEKIR----EQEEKIR--- 581
Query: 430 HIWGSYWKEGRWGYKCCHSFFKYSYCTGEAGKEIVNSEECIINEITGEESVKKPQTLMEL 489
E ++I EE I + EE +++ + +M+
Sbjct: 582 ----------------------------EQKEKIREQEEKIWEQ---EEKIREQEEMMQE 610
Query: 490 HQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETMQ 544
+EK+ E+++K ++++K ++E+K + ++ + +E RL +E MQ
Sbjct: 611 QEEKMWEQEEKMCEQEEK-------MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 658
Score = 31.6 bits (70), Expect = 2.1
Identities = 35/172 (20%), Positives = 71/172 (41%), Gaps = 5/172 (2%)
Query: 412 RAVACSKYEEDVKIHNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAGKEIVNSEECII 471
R + C K E + ++ H E R H +K++ +A + ++
Sbjct: 133 RILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKAD 192
Query: 472 NEITGEESVKKPQTL-MELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALN 530
I EE K+ L +EL++ + +E+ K+K K + + +S+ E + +
Sbjct: 193 RYI--EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRK 250
Query: 531 AEEARLLHVKETMQ--IDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDPM 580
E A+LL ++ +Q D + S+ + EE E + Q+ ++ M
Sbjct: 251 LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKM 302
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 48.5 bits (114), Expect = 2e-05
Identities = 38/141 (26%), Positives = 65/141 (46%), Gaps = 16/141 (11%)
Query: 458 EAGKEIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHR-------- 509
+ G + + E +NE +E K + L+ ++ K+ ++KKK+KKK R
Sbjct: 52 KTGSKALAEFEEKMNENWKKELEKSREKLLSGNESSSKKRERKKKRKKKSCRSSSSSSSS 111
Query: 510 ---KSSSDSDDEEKKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEM 566
SSSDS+DEEKK K +K + E K ++++ TE+E
Sbjct: 112 DSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEK 171
Query: 567 EAYRMKRQR----PDD-PMAS 582
+ + ++R PDD P++S
Sbjct: 172 DVRSLSKKRKKSYPDDKPLSS 192
Score = 33.9 bits (76), Expect = 0.43
Identities = 23/89 (25%), Positives = 46/89 (51%), Gaps = 10/89 (11%)
Query: 495 KEEKKKKKKKKKKHR------KSSSDSDDEEKKHEKLKKALNAEEARLLHVKETMQIDER 548
+E+K+ K++KKKK+R S+ +S+ E K+ K KK E + V+ + ++
Sbjct: 123 EEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKRKK 182
Query: 549 K----RPYNSMYETREPTEEEMEAYRMKR 573
+P +S + EE+++A + +R
Sbjct: 183 SYPDDKPLSSESSSESDYEEDVQAKKKRR 211
Score = 33.1 bits (74), Expect = 0.73
Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 8/85 (9%)
Query: 472 NEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKH-------RKSSSDSDDEEKKHEK 524
+E +ESVKK + + EK K+ + KK+KK + +SSS+SD EE K
Sbjct: 149 SESESKESVKKKKKSKD-ETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAK 207
Query: 525 LKKALNAEEARLLHVKETMQIDERK 549
K+ E VK+ + +K
Sbjct: 208 KKRRCEEREQAKEKVKKKKKKQHKK 232
Score = 31.6 bits (70), Expect = 2.1
Identities = 18/57 (31%), Positives = 27/57 (47%)
Query: 464 VNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEK 520
++SE ++ + KK + E Q K K +KKKKK+ KK +K S K
Sbjct: 190 LSSESSSESDYEEDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHK 246
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 48.1 bits (113), Expect = 2e-05
Identities = 33/115 (28%), Positives = 56/115 (48%), Gaps = 1/115 (0%)
Query: 461 KEIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEK 520
K+ +EE E T EE K+ + E +EK KE++KKKK K+ + RK + + + K
Sbjct: 5 KKKKETEETEETEETEEEEEKEGKR-KEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63
Query: 521 KHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQR 575
+ K KK E +E + +E++ + + +EE E + KR+R
Sbjct: 64 RKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118
Score = 43.5 bits (101), Expect = 5e-04
Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 15/99 (15%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
E+ KK E +EK +EEKK+K+K+KKK + + ++EE++ EK
Sbjct: 39 EKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEK------------ 86
Query: 537 LHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQR 575
+E + + R+R +E EE+ + R K ++
Sbjct: 87 ---EEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122
Score = 42.0 bits (97), Expect = 0.002
Identities = 26/101 (25%), Positives = 51/101 (50%), Gaps = 18/101 (17%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
EE+ + +T E +E ++EK+K+K+K+K+ +K + +++ ++K E+ KK
Sbjct: 11 EETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR-------- 62
Query: 537 LHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPD 577
+RKR E RE EEE E + + ++ +
Sbjct: 63 ----------KRKRKKKKEEEEREEEEEEEEEEKEEEEKEE 93
Score = 38.5 bits (88), Expect = 0.017
Identities = 23/79 (29%), Positives = 44/79 (55%), Gaps = 7/79 (8%)
Query: 500 KKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETR 559
KKKKKKKK + + ++++ E++ EK K +E R KE + E+K+ + +
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKR---KEKR----KEKRKEKEKKKKTKETEKRK 53
Query: 560 EPTEEEMEAYRMKRQRPDD 578
E EEE + R ++++ ++
Sbjct: 54 EKEEEEKKRKRKRKKKKEE 72
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 48.1 bits (113), Expect = 2e-05
Identities = 96/574 (16%), Positives = 225/574 (39%), Gaps = 73/574 (12%)
Query: 18 KEMSLEEPKKMTREDWRKKKELEEQRKLGNAPAEVDEEGKD------INPHIPQYISSVP 71
+ L+E + +ED +++ +EQR+ +++EE K P + + +
Sbjct: 845 RAQQLQEEEDGLQEDQERRRS-QEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQ 903
Query: 72 WYIDPSKRPTLKHQRPQPEKQKQFSSSGEWYKRGVKENSIITKYRKGACENCGAMTHKKK 131
+ + + +R + +Q+Q E + +E ++ + R+ +++
Sbjct: 904 QLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE----------KRRR 953
Query: 132 DCFERPRRVGAKFTGTNIAPDEHVQPQLMFDYDGKR---DRWNGYNPEEHMKIVEEYAKV 188
ER R K + + QL+ + KR +R Y EE ++ EE
Sbjct: 954 QERERQYRKDKKL--------QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQL-- 1003
Query: 189 DLAKRTLKAQKLQEELASGKLVEQANSPKHQWGEEEPNSQMEKDHNSEDEDEDKYADDID 248
L + K ++ + E K E + EE ++++ E+E+ ++
Sbjct: 1004 -LREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQ 1062
Query: 249 MPGQNFDSKRRITV-RNLRIREDIAKYLRNL---DPNSAYYDPKTRAMRENPYANAGKNP 304
+ G+ +++RR + R R E++ + L +P + R RE
Sbjct: 1063 LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREE--------- 1113
Query: 305 DEVSYAGDNFVRYTGDTISMAQTQLFAWEAYDKGSEVHLQADPTKLELLYKSFKVKKEDF 364
+E+ + +R + + + Y + EV + + ++ +E+
Sbjct: 1114 EELQQEEEQLLREEREKRRRQELE----RQYREEEEVQQEEE-----------QLLREEP 1158
Query: 365 KEQQKESILEKYGGQEHLDAPPAELLLAQTEDY-VEYSRHGTVIKGQERAVACSKYEEDV 423
++++++ + +Y +E L +LL + E E R + +R +Y ++
Sbjct: 1159 EKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDED 1218
Query: 424 KIHNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAGKEIVNSEECIINEITGEESVKKP 483
+ + W + K YC G ++ E+ +++ +S +
Sbjct: 1219 QRSDLKWQWEPEKENAVRDNKV--------YCKGRENEQFRQLED---SQLRDRQSQQDL 1267
Query: 484 QTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETM 543
Q L+ QE+ +E+++++ +++ +H + EE+K K + + EE +LL +E
Sbjct: 1268 QHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLL--REER 1325
Query: 544 QIDERKRPYNSMYETREPTEEEMEAYRMKRQRPD 577
+ R++ + + E +E E ++RQ D
Sbjct: 1326 EEKRRRQETDRKFREEEQLLQEREEQPLRRQERD 1359
Score = 42.4 bits (98), Expect = 0.001
Identities = 103/600 (17%), Positives = 238/600 (39%), Gaps = 72/600 (12%)
Query: 18 KEMSLEEPKKMTREDWRKKKELEEQRKLGNAPAEVDEEGKD-INPHIPQY---------I 67
+E L+ ++ R + R K+E EE+R+ E E+ ++ I IP++
Sbjct: 655 REQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADA 714
Query: 68 SSVPWYIDPSKRPTLKHQRPQPEKQKQFSSSGEWYKRGVKENSIITKYRKGACENCGAMT 127
Y P K+ + ++ Q EK+++ S +W +E + ++
Sbjct: 715 RQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQ----EEERAHRQQQEEEQRRDFTWQ 770
Query: 128 HKKKDCFERPR-RVGAK-----FTGTNIAPDEHVQPQLMF---DYDGKRDRWNGYNPEEH 178
+ ++ ER R R+ A+ + +E Q + F + + ++ R E+
Sbjct: 771 WQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKE 830
Query: 179 MKIVEEYAKVDLAKRTLKAQK----LQEELASGKLVEQANSPKHQWGEEEPNSQMEKDHN 234
++ +EE ++ +R + Q+ LQE+ + EQ K +W EE +
Sbjct: 831 LQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLY 890
Query: 235 SEDEDEDKYADDIDMPGQNFDSKRRITVRNLRIREDIAKYLRNLDPNSAYYDPKTRAMRE 294
++ +++ + + + + +R R R R++ + R + + R RE
Sbjct: 891 AKPALQEQLRKEQQLLQEEEEELQR-EEREKRRRQEQERQYREEEQLQQEEEQLLREERE 949
Query: 295 NPYANAGKNPDEVSYAGDNFVRYTGDTISMAQTQLFAWEAYDKGSEVHLQADPTKLELLY 354
+ E Y D + + QL E + + + + EL
Sbjct: 950 ----KRRRQERERQYRKDK-------KLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ 998
Query: 355 KSFKVKKEDFKEQQKESILEKYGGQEHLDAPPAELLLAQTEDYVEYSRHGTVIKGQERAV 414
+ ++ +E+ ++++++ +Y ++ L +LL + E + QER
Sbjct: 999 EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKR----------RLQERE- 1047
Query: 415 ACSKYEEDVKIHNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAGKEIVNSEECIINEI 474
+Y E+ ++ +E R + + K E ++++ E
Sbjct: 1048 --RQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE-EQLLREEPEKRRRQ 1104
Query: 475 TGEESVKKPQTLMELHQEKLKEEKKKKKKK--KKKHRKSSSDSDDEE---------KKHE 523
E ++ + L + ++ L+EE++K++++ ++++R+ +EE ++ +
Sbjct: 1105 ERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQ 1164
Query: 524 KLKK------ALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPD 577
+L++ L EE +LL ++ + ER+R Y E + ++ + YR + QR D
Sbjct: 1165 ELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQR--QKRKQRYRDEDQRSD 1222
Score = 37.7 bits (86), Expect = 0.030
Identities = 20/107 (18%), Positives = 58/107 (54%), Gaps = 3/107 (2%)
Query: 473 EITGEESVKKPQTLMELHQEKLKEEKKKKK-KKKKKHRKSSSDSDDEEKKHEKLKKALNA 531
++ E+ ++ Q L +++L++E+++++ K++++ R+ +EE++ ++LK+
Sbjct: 537 QLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEE 596
Query: 532 EEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDD 578
+ L +E ++++ +R + RE EEE +K + ++
Sbjct: 597 RLEQRLKREEVERLEQEERREQRL--KREEPEEERRQQLLKSEEQEE 641
Score = 37.0 bits (84), Expect = 0.050
Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 477 EESVKKPQTLM---ELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEE 533
E+ ++ Q L E Q++LK E++++ +++ K R+ + EE++ ++LK+ EE
Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLK-REEVERLEQEERREQRLKREEPEEE 628
Query: 534 ARLLHVKETMQIDER----KRPYNSMYETREPTEEEME--AYRMKRQRPDD 578
R +K Q + R +R E R EEE E R+KR+ ++
Sbjct: 629 RRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEE 679
Score = 36.6 bits (83), Expect = 0.066
Identities = 19/102 (18%), Positives = 50/102 (49%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
E+ +K +T++ +EKL+EE+ +++++ ++ + + +E + E+ ++ + R
Sbjct: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR 302
Query: 537 LHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDD 578
Q +ER+ E +E E++ E + +R +
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQE 344
Score = 36.2 bits (82), Expect = 0.086
Identities = 31/117 (26%), Positives = 58/117 (49%), Gaps = 18/117 (15%)
Query: 461 KEIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSD---SDD 517
+E +EE + G E+ + P +L + +L E ++K +++K++ R+ D ++
Sbjct: 183 REERRAEEEQLQSCKGHETEEFPDE-EQLRRRELLELRRKGREEKQQQRRERQDRVFQEE 241
Query: 518 EEKKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQ 574
EEK+ K + L EE E +Q +E +R RE EEE + +++RQ
Sbjct: 242 EEKEWRKRETVLRKEE-------EKLQEEEPQRQ-------RELQEEEEQLRKLERQ 284
Score = 36.2 bits (82), Expect = 0.086
Identities = 24/118 (20%), Positives = 62/118 (52%), Gaps = 15/118 (12%)
Query: 473 EITGEESVKKPQTLM-----ELHQEKLKEEKKKKKKKKKKH-------RKSSSDSDDEEK 520
++ E+ +++ Q L E H++K ++E+++++ K+++ R+ ++ ++E+
Sbjct: 412 QLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQER 471
Query: 521 KHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDD 578
+ ++LK+ EE R +K ++ +ER+ + +EE R+KRQ ++
Sbjct: 472 RKQQLKRD-QEEERRERWLK--LEEEERREQQERREQQLRREQEERREQRLKRQEEEE 526
Score = 35.4 bits (80), Expect = 0.15
Identities = 20/105 (19%), Positives = 52/105 (49%), Gaps = 6/105 (5%)
Query: 481 KKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVK 540
++ Q + K +EE+++ ++++++ + + +++H K + EE +LL +
Sbjct: 1419 EEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFR-----EEEQLLQER 1473
Query: 541 ETMQIDERKRPYNSMYETREPTEEEME-AYRMKRQRPDDPMASFL 584
E Q+ ++R + E ++ +E + +R + R +P FL
Sbjct: 1474 EEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFL 1518
Score = 34.7 bits (78), Expect = 0.25
Identities = 20/107 (18%), Positives = 52/107 (48%), Gaps = 8/107 (7%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
EE ++ Q E +++L+ E++++++++ K ++ + ++L++ +L
Sbjct: 492 EEEERREQ--QERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL 549
Query: 537 LHVKETMQIDERKRPYNSMYETRE------PTEEEMEAYRMKRQRPD 577
L +E ++++ +R E E EEE R+KR++ +
Sbjct: 550 LKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEE 596
Score = 34.3 bits (77), Expect = 0.33
Identities = 18/99 (18%), Positives = 52/99 (52%), Gaps = 8/99 (8%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
+E ++ Q L Q + K+E++++++++++ + EE++ ++L++ EE R
Sbjct: 291 QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR--EQEERRE 348
Query: 537 LHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQR 575
++ + + R++ + R EEE +++R++
Sbjct: 349 QQLRREQEEERREQ------QLRREQEEERREQQLRREQ 381
Score = 34.3 bits (77), Expect = 0.33
Identities = 22/111 (19%), Positives = 55/111 (49%), Gaps = 6/111 (5%)
Query: 473 EITGEESVKKPQTLMELHQEKLKEE----KKKKKKKKKKHRKSSSDSDDEEKKHEKLKKA 528
E E ++ Q L +E+ +E ++++++++++ R+ + EE++ ++LK+
Sbjct: 463 ETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQ 522
Query: 529 LNAE--EARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPD 577
E + RL ++ + E +R E + E+E R+KR++ +
Sbjct: 523 EEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEE 573
Score = 32.7 bits (73), Expect = 0.95
Identities = 23/102 (22%), Positives = 52/102 (50%), Gaps = 6/102 (5%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSS------DSDDEEKKHEKLKKALN 530
E+ +K+ + E Q+ LK E+++++++++ R+ ++EE++ E+ K +
Sbjct: 617 EQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREH 676
Query: 531 AEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMK 572
EE R + E Q R+R + + + + E E +A + K
Sbjct: 677 EEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSK 718
Score = 32.0 bits (71), Expect = 1.6
Identities = 24/95 (25%), Positives = 51/95 (53%), Gaps = 13/95 (13%)
Query: 488 ELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETMQI-- 545
E ++ L+EE++ ++++ +K R ++E+ E+ ++ L+ +E ++E Q+
Sbjct: 1443 ERERKFLEEEQQLRQERHRKFR------EEEQLLQEREEQQLHRQERDRKFLEEEQQLRR 1496
Query: 546 DERKRPYNSM-YETREPT----EEEMEAYRMKRQR 575
ER R + ++EP EEE + +R +RQR
Sbjct: 1497 QERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR 1531
Score = 31.2 bits (69), Expect = 2.8
Identities = 22/109 (20%), Positives = 53/109 (48%), Gaps = 10/109 (9%)
Query: 473 EITGEESVKKPQTL---MELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKAL 529
++ E+ +++ Q L +L +E+ +++ +++++ R+ + EE++HE+ K
Sbjct: 382 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQ-KHEQ 440
Query: 530 NAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDD 578
E RL + E +R + E E E+E ++KR + ++
Sbjct: 441 ERREQRL------KREQEERRDWLKREEETERHEQERRKQQLKRDQEEE 483
Score = 30.0 bits (66), Expect = 6.2
Identities = 19/99 (19%), Positives = 47/99 (47%), Gaps = 4/99 (4%)
Query: 481 KKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVK 540
++PQ EL +E EE+ +K ++++ R+ + +++ + + EE R +
Sbjct: 263 EEPQRQRELQEE---EEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319
Query: 541 ETMQIDERKRPYNSMYETR-EPTEEEMEAYRMKRQRPDD 578
E + ER+ E + +EE +++R++ ++
Sbjct: 320 ERREQQERREQQEERREQQLRREQEERREQQLRREQEEE 358
Score = 30.0 bits (66), Expect = 6.2
Identities = 24/103 (23%), Positives = 53/103 (51%), Gaps = 11/103 (10%)
Query: 473 EITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAE 532
++ +ES +K + +L QE+ +E++ + +++ K+R ++E+ + E+ ++ L E
Sbjct: 1787 QLRSQESDRKFREEEQLRQER-EEQQLRPQQRDGKYR-----WEEEQLQLEEQEQRLRQE 1840
Query: 533 EARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQR 575
R +E E+ R E +E +EE + R +R+R
Sbjct: 1841 RDRQYRAEEQFATQEKSR-----REEQELWQEEEQKRRQERER 1878
Score = 29.6 bits (65), Expect = 8.1
Identities = 32/135 (23%), Positives = 57/135 (42%), Gaps = 17/135 (12%)
Query: 455 CTGEAGKEIVNSEECIINEIT-----GEESVKKPQTLMELHQEKLKEEKKKK-KKKKKKH 508
C G +E + E+ E+ G E +K Q E +EE++K+ +K++
Sbjct: 196 CKGHETEEFPDEEQLRRRELLELRRKGRE--EKQQQRRERQDRVFQEEEEKEWRKRETVL 253
Query: 509 RKSSSDSDDEE--------KKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETRE 560
RK +EE ++ E+L+K L +E R +E Q +R + E
Sbjct: 254 RKEEEKLQEEEPQRQRELQEEEEQLRK-LERQELRRERQEEEQQQQRLRREQQLRRKQEE 312
Query: 561 PTEEEMEAYRMKRQR 575
E+ E R +++R
Sbjct: 313 ERREQQEERREQQER 327
Score = 29.6 bits (65), Expect = 8.1
Identities = 19/104 (18%), Positives = 49/104 (47%), Gaps = 1/104 (0%)
Query: 467 EECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLK 526
EE ++ E+ ++ Q L +E+ E++ K++ ++++ + ++ +++E+ E++K
Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE-EEQEQARERIK 698
Query: 527 KALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYR 570
+ + +L + Q RP + R +EE R
Sbjct: 699 SRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRR 742
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 47.4 bits (111), Expect = 4e-05
Identities = 28/99 (28%), Positives = 51/99 (51%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
EE +K + + ++E ++EK+KKK+KK++ R S + E K+ K ++ E +
Sbjct: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
Query: 537 LHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQR 575
KE + + +KR + E E +E+ R KR+R
Sbjct: 153 EREKERERKERKKRERKQVGEKEEERKEKERKERKKRER 191
Score = 45.4 bits (106), Expect = 1e-04
Identities = 28/99 (28%), Positives = 53/99 (53%), Gaps = 9/99 (9%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
E+ K+ + E E+ KEE+++KK++++K K + ++ KK EK ++ ++E +
Sbjct: 74 EKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEK-EKRKKKEKKERGRTSKEGKE 132
Query: 537 LHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQR 575
KE + +ERK RE +EE E R +++R
Sbjct: 133 RERKEERKREERKE--------RERKKEEREKERERKER 163
Score = 41.2 bits (95), Expect = 0.003
Identities = 26/103 (25%), Positives = 52/103 (50%), Gaps = 7/103 (6%)
Query: 476 GEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEAR 535
G+E +K + E +E+ +++++++K++++K RK EK+ E+ +K + R
Sbjct: 130 GKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKR 189
Query: 536 LLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDD 578
+ KE + ERK E RE +E + K++R D
Sbjct: 190 ERNRKERKKERERK-------ERRERKKERKKKEERKKERQKD 225
Score = 36.6 bits (83), Expect = 0.066
Identities = 26/114 (22%), Positives = 52/114 (45%), Gaps = 1/114 (0%)
Query: 462 EIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKK 521
EI E I G++ + + +EK K E++K++K+++ ++ + EE++
Sbjct: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96
Query: 522 HEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQR 575
+K ++ +E ++ + ER R E RE EE R +R+R
Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKE-RERKEERKREERKERER 149
Score = 36.6 bits (83), Expect = 0.066
Identities = 30/124 (24%), Positives = 56/124 (45%), Gaps = 8/124 (6%)
Query: 456 TGEAGKEIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKK----KKKKKKKKHRKS 511
T + GKE EE E E K+ + +E+ K E+K K++++K+K RK
Sbjct: 126 TSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKE 185
Query: 512 SSDSDDEEKKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRM 571
+ K+ +K ++ E + KE + +ERK+ +T +E + R
Sbjct: 186 RKKRERNRKERKKERERKERRERK----KERKKKEERKKERQKDRQTNWREKERGKRERK 241
Query: 572 KRQR 575
+R++
Sbjct: 242 ERKK 245
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 46.6 bits (109), Expect = 6e-05
Identities = 77/444 (17%), Positives = 173/444 (38%), Gaps = 47/444 (10%)
Query: 166 KRDRWNGYNPEEHMKIVEEYAKVDLAKRTLKAQKLQEELASGKLVEQANSPKHQ----WG 221
+ + WN N ++ K+ + K+ + ++ Q+ + K+ EQ + Q W
Sbjct: 287 ENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE 346
Query: 222 EEEPNSQMEKDHNSEDEDEDKYADDIDMPGQNFDSKRRITVRNLRIREDIAKYLRNLDPN 281
+EE +M + E E+K +M + + RR E I + +
Sbjct: 347 KEE---KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 403
Query: 282 SAYYDPKTRAMRENPYANAGKNPDEVS--YAGDNFVRYTGDTISMAQTQLFAWEAYDKGS 339
+ + + E K ++ + + + +R + I + +++ E
Sbjct: 404 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQE-----E 458
Query: 340 EVHLQADPTKLELLYKSFKVKKEDFKEQQKESIL---EKYGGQEHLDAPPAELLLAQTED 396
++H Q + E + ++ +++ K ++E I EK QE E + Q E
Sbjct: 459 KIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEK 518
Query: 397 YVEYS-----------RHGTVIKGQERAVACSKYEEDVKIHNHTHIWGSYWKEGRWGYKC 445
E R I+ QE + E+ K+H IW ++ +
Sbjct: 519 IREQEEKIREQEEKMWRQEEKIREQEEM-----WREEEKMHEQEKIWEEEKRQEQED--- 570
Query: 446 CHSFFKYSYCTGEAGKEIVNSEECIINEITG----EESVKKPQTLMELHQEKLKEEKKKK 501
++ E +++ EE I + EE + K + + +EK++E+++K
Sbjct: 571 --KMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI 628
Query: 502 KKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETM-----QIDERKRPYNSMY 556
+++++K R+ + ++E+K + ++ + +E ++ +ETM +I E+++
Sbjct: 629 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQE 688
Query: 557 ETREPTEEEMEAYRMKRQRPDDPM 580
E EE M+ K ++ M
Sbjct: 689 EKIREQEEMMQEQEEKMWEQEEKM 712
Score = 37.4 bits (85), Expect = 0.039
Identities = 17/73 (23%), Positives = 44/73 (60%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
EE +++ + M +EK++E++KK +++++K R+ ++E+K + ++ + +E ++
Sbjct: 660 EEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 719
Query: 537 LHVKETMQIDERK 549
+E M+ E K
Sbjct: 720 QEQEEKMRRQEEK 732
Score = 32.0 bits (71), Expect = 1.6
Identities = 20/104 (19%), Positives = 52/104 (50%), Gaps = 2/104 (1%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
EE + + + M +EK++E+++ ++++K R+ ++E+K + ++ + +E ++
Sbjct: 646 EEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 705
Query: 537 LHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDPM 580
+E M E K E EE+M ++ ++ ++ M
Sbjct: 706 WEQEEKMCEQEEK--MQEQEEKMRRQEEKMWEQEVRLRQQEEKM 747
Score = 31.6 bits (70), Expect = 2.1
Identities = 35/172 (20%), Positives = 71/172 (41%), Gaps = 5/172 (2%)
Query: 412 RAVACSKYEEDVKIHNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAGKEIVNSEECII 471
R + C K E + ++ H E R H +K++ +A + ++
Sbjct: 133 RILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKAD 192
Query: 472 NEITGEESVKKPQTL-MELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALN 530
I EE K+ L +EL++ + +E+ K+K K + + +S+ E + +
Sbjct: 193 RYI--EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRK 250
Query: 531 AEEARLLHVKETMQ--IDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDPM 580
E A+LL ++ +Q D + S+ + EE E + Q+ ++ M
Sbjct: 251 LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKM 302
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 46.6 bits (109), Expect = 6e-05
Identities = 85/447 (19%), Positives = 168/447 (37%), Gaps = 89/447 (19%)
Query: 176 EEHMKIVEEYAKVDLAKRTLKAQKLQEELAS-GKLVEQANSPKHQWGEEEP-----NSQM 229
E + + E K++ AK L Q+LQ E GK ++ ++ EE N Q
Sbjct: 300 EIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQ 359
Query: 230 EKDHNSEDEDEDKYADDIDMPGQNFDSKRRITVRNLRIREDIAKYLRNLDPNSAYYDPKT 289
E+ ++E ++ + I + + +I + +IRE K +R + + K
Sbjct: 360 EEKMWRQEEKIQEWEEKIQ------EQEEKIREQEEKIREQEEK-MRRQEEMMWEKEEKM 412
Query: 290 RAMRENPYANAGKNPDEVSYAGDNFVRYTGDTISMAQTQLFAWEAYDKGSEVHLQADPTK 349
R E + K M + + WE +K E+
Sbjct: 413 RRQEEMMWEKEEK---------------------MRRQEEMMWEKEEKIRELE------- 444
Query: 350 LELLYKSFKVKKEDFKEQQKESILE----------------KYGGQEHLDAPPAELLLAQ 393
E +++ K+++++ K Q++E I E K QE E + Q
Sbjct: 445 -EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQ 503
Query: 394 TEDYVEYSRHGTVIKGQERAVACSKYEEDVKIHNHTHIWGS-----------------YW 436
E E + K QE+ + ++ KI IW W
Sbjct: 504 EEKIHEQEKIREEEKRQEQE---EMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMW 560
Query: 437 KEGRWGYKCCHSFFKYSYCTGEAGKEIVNSEECIINEITGEESVKKPQTLMELHQEKLKE 496
++ + + ++I EE I + EE +++ + + + +EK+ E
Sbjct: 561 RQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQ---EEKIREQEEMTQEQEEKMGE 617
Query: 497 EKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMY 556
+++K ++++K ++ +E+K + +K + +E ++ +E MQ E K M+
Sbjct: 618 QEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK-----MW 672
Query: 557 ETRE---PTEEEMEAYRMKRQRPDDPM 580
E E EE+M+ K +R ++ M
Sbjct: 673 EQEEKMCEQEEKMQEQEEKMRRQEEKM 699
Score = 36.2 bits (82), Expect = 0.086
Identities = 21/104 (20%), Positives = 54/104 (51%), Gaps = 2/104 (1%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
EE + + + M +EK++E+++K +++++K R+ ++E+K + ++ + +E ++
Sbjct: 612 EEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 671
Query: 537 LHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDPM 580
+E M E K E EE+M ++ ++ ++ M
Sbjct: 672 WEQEEKMCEQEEK--MQEQEEKMRRQEEKMWEQEVRLRQQEEKM 713
Score = 35.4 bits (80), Expect = 0.15
Identities = 79/398 (19%), Positives = 155/398 (38%), Gaps = 50/398 (12%)
Query: 166 KRDRWNGYNPEEHMKIVEEYAKVDLAKRTLKAQKLQEELASGKLVEQANSPKHQWGEEEP 225
+ + WN N ++ K+ + K+ Q+ +E K+ EQ + Q EE+
Sbjct: 348 ENELWNRLNQQQEEKMWRQEEKI---------QEWEE-----KIQEQEEKIREQ--EEKI 391
Query: 226 NSQMEKDHNSED---EDEDKYADDIDMPGQNFDSKRRITVRNLRIREDIAKYLRNLDPNS 282
Q EK E+ E E+K +M + + RR E I + +
Sbjct: 392 REQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 451
Query: 283 AYYDPKTRAMRENPYANAGKNPDEVS--YAGDNFVRYTGDTISMAQTQLFAWEAYDKGSE 340
+ + + E K ++ + + + +R + I + ++ W +K E
Sbjct: 452 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKM--WRQEEKIHE 509
Query: 341 VHLQADPTKL----ELLYKSFKVKKEDFKEQQKESILE---KYGGQEHLDAPPAELLLAQ 393
+ K E+ + K+++++ +QKE I E K QE E + Q
Sbjct: 510 QEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQ 569
Query: 394 TEDYVEYS----RHGTVIKGQERAVACSKYEEDVKIHNHTHIWGSYW-KEGRWGYKCCHS 448
E E R I+ QE + E++ KI + K G K C
Sbjct: 570 EEKIREQEEKVWRQEEKIREQEEKIR----EQEEKIREQEEMTQEQEEKMGEQEEKMCEQ 625
Query: 449 FFKYSYCTGEAGK--EIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKK 506
K + + E + +E I E EE +++ + +M+ +EK+ E+++K ++++
Sbjct: 626 EEKMQEQEEKMRRQEEKIREQEKKIRE--QEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 683
Query: 507 KHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETMQ 544
K ++E+K + ++ + +E RL +E MQ
Sbjct: 684 K-------MQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 714
Score = 31.6 bits (70), Expect = 2.1
Identities = 35/172 (20%), Positives = 71/172 (41%), Gaps = 5/172 (2%)
Query: 412 RAVACSKYEEDVKIHNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAGKEIVNSEECII 471
R + C K E + ++ H E R H +K++ +A + ++
Sbjct: 194 RILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKAD 253
Query: 472 NEITGEESVKKPQTL-MELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALN 530
I EE K+ L +EL++ + +E+ K+K K + + +S+ E + +
Sbjct: 254 RYI--EELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRK 311
Query: 531 AEEARLLHVKETMQ--IDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDPM 580
E A+LL ++ +Q D + S+ + EE E + Q+ ++ M
Sbjct: 312 LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKM 363
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 46.2 bits (108), Expect = 8e-05
Identities = 111/589 (18%), Positives = 233/589 (39%), Gaps = 66/589 (11%)
Query: 14 LSGSKEMSLEEPKKMTREDWRKKKELEEQRKLGNAPAEVDEEGKDINPHIPQYISSVPWY 73
L+ +E+ ++E +K+ + K+K EE+ +LG ++ E+ + ++I+S+
Sbjct: 1770 LAQEEELLIQEKEKLAQH---KEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSME-- 1824
Query: 74 IDPSKRPTLKHQRPQPEKQKQFSSSGEWYKRGVKENSIITKYRKGACENCGAMTHKKKDC 133
+ +K + +Q+ ++K+ + + KEN + K R +TH KK
Sbjct: 1825 -ELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYNKER---------LTHSKKQL 1874
Query: 134 FERPRRVGAKFTGTNIAPDEHV---------QPQLMFDYDGKRDRWNGYNPEEHMKIVEE 184
+ ++G F +E + + + + + + K + ++ K+ +E
Sbjct: 1875 VQVKNKLGM-FNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQE 1933
Query: 185 YAKVDLAKRTLKAQK-LQEELASGKLVEQANSPKHQWGEE-----EPNSQMEKDHNSEDE 238
K+ L K ++ +K L+ EL K + N + EE E + K E
Sbjct: 1934 KMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETS 1993
Query: 239 DEDKYAD-DIDMPGQNFDSKRRITVRNLRI----REDIAKYLRNLDPNSAYYDPKTRAMR 293
+ K + ++ + + +I + RI +IAK + R +
Sbjct: 1994 RQRKMTQVEQELFERKLSLEEKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLA 2053
Query: 294 E------NPYANAGKNPDEVSYAGDNFVRYTGDTISMAQTQLFAWEAYDK--GSEVHLQA 345
+ + K P +++ + T D + Q ++ + E L
Sbjct: 2054 KASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSI 2113
Query: 346 DPTKLELLYKSFKVKKEDFKEQQKESILEKYGGQEHLDAPPAELLLAQTEDYVEYS---- 401
+ +KL++ F K+ + + +K K ++ A ++ + E E
Sbjct: 2114 EQSKLDIKEWDFSEKRSELTKDEK-----KLARKQRKLANKMRRMINKEEKMTEEESKLA 2168
Query: 402 -RHGTVIKGQERAVACSKYEEDVKIHNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAG 460
+H VI E EE+ I W KE + G K K+S E
Sbjct: 2169 RKHSEVILDDEEE---GGIEEEEVIPFLKRRWRKR-KEAKRGDKPKE---KFSSQVDEVE 2221
Query: 461 KEIVNSEEC--IINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDE 518
E SEE +++E+ +ES+ + +E+ +EE+ +++++++K + + E
Sbjct: 2222 SEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVE 2281
Query: 519 EKKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEME 567
+++ EK KK +E + V+E ++ E K S ET ++EE E
Sbjct: 2282 KEEEEKKKK---KKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEE 2327
Score = 37.4 bits (85), Expect = 0.039
Identities = 83/417 (19%), Positives = 166/417 (39%), Gaps = 65/417 (15%)
Query: 167 RDRWNGYNPEEHMKIVEEYAKVDLAKRTLKAQKLQEELASGKLVEQANSPKHQWGEEEPN 226
R W + E ++++E K+ A L + EE+ L E +W + N
Sbjct: 1475 RKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPE---EEM----LQEDKKLKWEEWKQVWEN 1527
Query: 227 --SQMEKDHNSEDEDEDKYADDIDMPGQNFDSKRRITVRNLRIRED-----IAKYLRNLD 279
S K+ +DE+E +++ G+ + ++++T I+E+ I + +
Sbjct: 1528 MLSSKSKEQQYKDEEEVTLEEEVSREGE--EKEQQVTEEQRHIQEEHKWARIHRKRARAE 1585
Query: 280 PNSAYYDPKTRAMRENPYANAGKNPDEVSYAGDNFVRYTGDTISMAQTQ-LFAWEAY--- 335
A + K E + E +V+ T D MAQ + FA +
Sbjct: 1586 KKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLA 1645
Query: 336 DKGSEVHLQADPTKLELLYKSFKVKKEDFKEQQKESILEKYGGQEHLDAPPAELLLAQTE 395
+G ++ +A+ +L K K+ K+ K ++E L K GG+ + +LAQ
Sbjct: 1646 QRGEKLSQEAE----KLAQKRKKLAKKWEKVAREEEKLAKKGGK----LAEVKNILAQKV 1697
Query: 396 DYVEYSRHGTVIKGQERAVACSKYEEDVKIHNHTHIWGSYWKEGRWGYKCCHSFFKYSYC 455
+ + + +E A + E D++ + WKE
Sbjct: 1698 EELPQREQNLDWQEKELAQELEELEWDMEELS--------WKEEELNQ------------ 1737
Query: 456 TGEAGKEIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDS 515
E GK +V ++ + E EE++ + + + KL +E++ ++K+K +
Sbjct: 1738 --EEGK-LVEEKKKLAEE---EEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKM 1791
Query: 516 DDEEKKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMK 572
+EE++ + ++ L ++ +L +R+R NSM E T+ +M Y+ K
Sbjct: 1792 PEEEERLGRKREQLIEKKMKL--------AQKRERWINSM---EELTKNKMILYQKK 1837
Score = 35.8 bits (81), Expect = 0.11
Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 6/96 (6%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
E+S+ K Q +L QEK+K +K + KK + D EEK K L E+ RL
Sbjct: 1920 EDSLAKKQE--KLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRL 1977
Query: 537 LHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMK 572
+ KET+ E P S R+ T+ E E + K
Sbjct: 1978 VEGKETLSKGE--TPETS--RQRKMTQVEQELFERK 2009
Score = 31.2 bits (69), Expect = 2.8
Identities = 28/126 (22%), Positives = 53/126 (42%), Gaps = 16/126 (12%)
Query: 465 NSEECIINEITGEESVKKPQTLMELHQEKLKEEKK------KKKKKKKKHRKSSSDSDDE 518
+ EE + E E +K Q + E Q ++EE K K+ + +KK + E
Sbjct: 1540 DEEEVTLEEEVSREGEEKEQQVTE-EQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQE 1598
Query: 519 EKKHEKLKKALNAEEARLLHVKETMQIDERK---------RPYNSMYETREPTEEEMEAY 569
E+K + ++ L EE +L + D+R+ + ++ + E +E E
Sbjct: 1599 EEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKL 1658
Query: 570 RMKRQR 575
KR++
Sbjct: 1659 AQKRKK 1664
Score = 31.2 bits (69), Expect = 2.8
Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 7/90 (7%)
Query: 488 ELHQE--KLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETMQI 545
EL+QE KL EEKKK ++++ +EE K + ++ L E+ +L KE M
Sbjct: 1734 ELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPE 1793
Query: 546 DERKRPYNSMYETREPTEEEMEAYRMKRQR 575
+E + + RE E+ KR+R
Sbjct: 1794 EEER-----LGRKREQLIEKKMKLAQKRER 1818
Score = 29.6 bits (65), Expect = 8.1
Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 3/77 (3%)
Query: 495 KEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETMQIDERKRPYNS 554
KEEK +++ K + S DDEE+ + ++ + + R KE + D+ K ++S
Sbjct: 2156 KEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSS 2215
Query: 555 M---YETREPTEEEMEA 568
E+ E EEME+
Sbjct: 2216 QVDEVESEEHFSEEMES 2232
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 45.4 bits (106), Expect = 1e-04
Identities = 30/91 (32%), Positives = 47/91 (51%), Gaps = 8/91 (8%)
Query: 488 ELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETMQIDE 547
E Q + ++ KK++KKK++K RK + E+K +K KK E+ R + KE + E
Sbjct: 126 ENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKE-EREKKRERNRKERKKERE 184
Query: 548 RKRPYNSMYETREPTEEEMEAYRMKRQRPDD 578
RK E RE +E + R K++R D
Sbjct: 185 RK-------ERRERKKERKKERRKKKERKKD 208
Score = 41.2 bits (95), Expect = 0.003
Identities = 27/110 (24%), Positives = 55/110 (50%), Gaps = 2/110 (1%)
Query: 466 SEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKL 525
S+ C E ++ ++ + +++ K E+ KK+KKK+K R+ + + + K+ EK
Sbjct: 26 SKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
Query: 526 KKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQR 575
+K E+ R KE + + ++R + +E E E E + +R+R
Sbjct: 86 RKE-RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERE-NKQRRER 133
Score = 41.2 bits (95), Expect = 0.003
Identities = 25/100 (25%), Positives = 50/100 (50%), Gaps = 11/100 (11%)
Query: 476 GEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEAR 535
G+E +K + + +E+ ++E++K+KK+KKK + + +KK E+ ++
Sbjct: 72 GKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERE------- 124
Query: 536 LLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQR 575
+E Q ERKR + R+ + E E + +R+R
Sbjct: 125 ----RENKQRRERKRKKRRKKKRRKERKREKERGKRERKR 160
Score = 38.9 bits (89), Expect = 0.013
Identities = 26/101 (25%), Positives = 50/101 (49%), Gaps = 5/101 (4%)
Query: 480 VKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEE--KKHEKLKKALNAEEARLL 537
+ KP T E ++K + E++K+K++++K RK +++ KK E+ K+ + R
Sbjct: 25 ISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREK 84
Query: 538 HVKETMQIDERKRPYNSMYETREP---TEEEMEAYRMKRQR 575
KE + + RKR R+ E + + R +R+R
Sbjct: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERER 125
Score = 37.4 bits (85), Expect = 0.039
Identities = 25/109 (22%), Positives = 49/109 (44%), Gaps = 10/109 (9%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKK----------KKKKKKHRKSSSDSDDEEKKHEKLK 526
+E K+ + E + K K+EKKK+ KKKK++ + + E+K +K +
Sbjct: 80 KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRR 139
Query: 527 KALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQR 575
K +E + + + +KR + RE +E + R +++R
Sbjct: 140 KKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER 188
Score = 35.0 bits (79), Expect = 0.19
Identities = 20/99 (20%), Positives = 49/99 (49%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
E K+ + + +EK + ++KK+KKK+++ ++ + ++++ E+ ++ E +
Sbjct: 76 ERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR 135
Query: 537 LHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQR 575
++ + ERKR R+ + + E KR+R
Sbjct: 136 KKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRER 174
Score = 32.3 bits (72), Expect = 1.2
Identities = 14/58 (24%), Positives = 32/58 (55%)
Query: 491 QEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETMQIDER 548
+++ KEE++KK+++ +K RK + + ++ ++ KK ++ R K Q D +
Sbjct: 161 KKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
Score = 30.4 bits (67), Expect = 4.7
Identities = 16/61 (26%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
E K+ + E +E+ ++E++++KK++KK R+ E KK K + +++ R
Sbjct: 167 EREKKRERNRKERKKERERKERRERKKERKKERRKKK----ERKKDRKTDRQTDSQVFRP 222
Query: 537 L 537
L
Sbjct: 223 L 223
Score = 30.0 bits (66), Expect = 6.2
Identities = 16/100 (16%), Positives = 48/100 (48%), Gaps = 2/100 (2%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKK--KKKKHRKSSSDSDDEEKKHEKLKKALNAEEA 534
E ++ + + ++K ++E+K++K+ K+++ RK + E+K+ K+ E
Sbjct: 126 ENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERER 185
Query: 535 RLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQ 574
+ ++ + ER++ + + + + + +R R+
Sbjct: 186 KERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 45.1 bits (105), Expect = 2e-04
Identities = 24/73 (32%), Positives = 41/73 (56%)
Query: 461 KEIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEK 520
K + +SE+ I + E+ K P+ + + ++K K+ KKK+KK K+K R + E+K
Sbjct: 808 KPLADSEKLPIQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKK 867
Query: 521 KHEKLKKALNAEE 533
K K KK + +E
Sbjct: 868 KSPKPKKKKHRKE 880
Score = 40.0 bits (92), Expect = 0.006
Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 10/86 (11%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKK--------KKKKHRKSSSDSDDEEKKHEKLKKA 528
E+ KKP+ + H+EK ++++KKK+K KKKKHRK + +KK + K+
Sbjct: 838 EKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKKSK--KQP 895
Query: 529 LNAEEARLLHVKETMQIDERKRPYNS 554
+EEA V+ +E+ P +S
Sbjct: 896 PGSEEAAGEPVQNGAPEEEQLPPESS 921
Score = 30.8 bits (68), Expect = 3.6
Identities = 22/92 (23%), Positives = 45/92 (48%), Gaps = 13/92 (14%)
Query: 490 HQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETMQIDERK 549
H++KL+++K++KK+K+K EKK ++ +L E + + + I +
Sbjct: 733 HRQKLEKDKRRKKRKEK------------EKKGKRRHSSLPTESDEDIAPAQQVDIVTEE 780
Query: 550 RPYNSMYETREPTEEEMEAYRMKRQRPDDPMA 581
P N++ + E ++ + YR D P+A
Sbjct: 781 MPENAL-PSDEDDKDPNDPYRALDIDLDKPLA 811
>gi|239752449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 170
Score = 44.7 bits (104), Expect = 2e-04
Identities = 24/62 (38%), Positives = 33/62 (53%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
E+ KK + + ++K K++KKKKKKKKKK RK + KK K KK E
Sbjct: 109 EKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKTGNEGAK 168
Query: 537 LH 538
+H
Sbjct: 169 IH 170
Score = 41.2 bits (95), Expect = 0.003
Identities = 20/40 (50%), Positives = 27/40 (67%)
Query: 488 ELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKK 527
E +EK KE+KKKKKKKKKK +K ++KK +K +K
Sbjct: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRK 142
Score = 40.4 bits (93), Expect = 0.005
Identities = 21/59 (35%), Positives = 34/59 (57%)
Query: 491 QEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETMQIDERK 549
+EK ++EK+KKKKKKKK +K ++KK +K KK + R K+ + ++K
Sbjct: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKK 161
Score = 40.0 bits (92), Expect = 0.006
Identities = 19/42 (45%), Positives = 28/42 (66%)
Query: 486 LMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKK 527
L + ++K KE++KKKKKKKKK +K ++KK +K KK
Sbjct: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKK 140
Score = 40.0 bits (92), Expect = 0.006
Identities = 19/45 (42%), Positives = 29/45 (64%)
Query: 483 PQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKK 527
PQ + +EK K++KKKKKKKKKK +K ++KK ++ +K
Sbjct: 100 PQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRK 144
Score = 40.0 bits (92), Expect = 0.006
Identities = 18/40 (45%), Positives = 27/40 (67%)
Query: 488 ELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKK 527
E +EK K++KKKKKKKKKK +K ++KK ++ +K
Sbjct: 107 EKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRK 146
Score = 39.7 bits (91), Expect = 0.008
Identities = 20/51 (39%), Positives = 30/51 (58%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKK 527
EE +K + + ++K K++KKKKKKKKKK +K + K+ K KK
Sbjct: 103 EEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKK 153
Score = 39.3 bits (90), Expect = 0.010
Identities = 20/68 (29%), Positives = 37/68 (54%)
Query: 483 PQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKET 542
P + LH +EEKK+K+K+KKK +K ++KK +K KK ++ + ++
Sbjct: 90 PSLHLPLHGLPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKR 149
Query: 543 MQIDERKR 550
+ +RK+
Sbjct: 150 KRKKKRKK 157
Score = 39.3 bits (90), Expect = 0.010
Identities = 19/52 (36%), Positives = 31/52 (59%)
Query: 491 QEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKET 542
++K K++KKKKKKKKKK +K ++K+ K K+ ++ R K+T
Sbjct: 111 EKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKKKKKT 162
Score = 38.9 bits (89), Expect = 0.013
Identities = 21/62 (33%), Positives = 34/62 (54%)
Query: 489 LHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETMQIDER 548
L Q + K+EK+K+KKKKKK +K ++KK +K KK + R K + ++
Sbjct: 99 LPQREEKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKKRKKK 158
Query: 549 KR 550
K+
Sbjct: 159 KK 160
Score = 38.1 bits (87), Expect = 0.023
Identities = 18/51 (35%), Positives = 31/51 (60%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKK 527
E+ K+ + + ++K K++KKKKKKKKKK +K ++K ++ KK
Sbjct: 104 EKKEKEKEKKKKKKKKKKKKKKKKKKKKKKKKKKKKKRKRKRKRKRKRKKK 154
>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
isoform 1 [Homo sapiens]
Length = 1112
Score = 43.5 bits (101), Expect = 5e-04
Identities = 26/68 (38%), Positives = 40/68 (58%), Gaps = 7/68 (10%)
Query: 461 KEIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEK 520
K + +SE+ I + E+ K P+ + + ++K K+ KKK+KK K+K R D+EK
Sbjct: 717 KPLADSEKLPIQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKER-------DKEK 769
Query: 521 KHEKLKKA 528
K EK KKA
Sbjct: 770 KKEKEKKA 777
Score = 31.2 bits (69), Expect = 2.8
Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 2/59 (3%)
Query: 496 EEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETMQIDERKRPYNS 554
++KK K KKKKHRK + +KK + K+ +EEA V+ +E+ P +S
Sbjct: 824 QDKKSPKPKKKKHRKEKEERTKGKKKSK--KQPPGSEEAAGEPVQNGAPEEEQLPPESS 880
Score = 30.8 bits (68), Expect = 3.6
Identities = 22/92 (23%), Positives = 45/92 (48%), Gaps = 13/92 (14%)
Query: 490 HQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETMQIDERK 549
H++KL+++K++KK+K+K EKK ++ +L E + + + I +
Sbjct: 642 HRQKLEKDKRRKKRKEK------------EKKGKRRHSSLPTESDEDIAPAQQVDIVTEE 689
Query: 550 RPYNSMYETREPTEEEMEAYRMKRQRPDDPMA 581
P N++ + E ++ + YR D P+A
Sbjct: 690 MPENAL-PSDEDDKDPNDPYRALDIDLDKPLA 720
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 43.5 bits (101), Expect = 5e-04
Identities = 73/419 (17%), Positives = 174/419 (41%), Gaps = 45/419 (10%)
Query: 173 YNPEEHMKIVEEYAKVDLAKRTLKAQKLQEELASGKLVEQANSPKHQWGEEEPNSQMEKD 232
+ EE ++ E+ + K + ++L+E+ GK+ EQ W +E+ + EK+
Sbjct: 275 WRQEEELREQEKKIRKQEEKMWRQEERLREQ--EGKMREQEEK---MWRQEKRLREQEKE 329
Query: 233 HNSEDEDEDKYADDIDMPGQNFDSKRRITVRNLRIREDIAKYLRNLDPNSAYYDPKTRAM 292
++++ + + + Q + + ++ + ++RE K R + + + M
Sbjct: 330 LREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER----LWEQEKQM 385
Query: 293 RENPYANAGKNPDEVSYAGDNFVRYTGDTISMAQTQLFAWEAYDKGSEVHLQADPTKL-- 350
RE ++ +E + D +R + + + Q WE +K E + K
Sbjct: 386 REQEQKM--RDQEERMWEQDERLREKEERM---REQEKMWEQVEKMREEKKMQEQEKKTR 440
Query: 351 ---ELLYKSFKVKKEDFKEQQKESILEKYGGQEHLDAPPAELLLAQTEDYVEYSR----- 402
E + + ++++ + K +++E + + QE E + Q E + R
Sbjct: 441 DQEEKMQEEERIREREKKMREEEETMRE---QEEKMQKQEENMWEQEEKEWQQQRLPEQK 497
Query: 403 ----HGTVIKGQERAVACSKYEEDVKIHNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGE 458
++ QE + +E++ KI + +WG K R + E
Sbjct: 498 EKLWEQEKMQEQEEKI----WEQEEKIRDQEEMWGQEKKMWRQ-----EKMREQEDQMWE 548
Query: 459 AGKEIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDE 518
+++ + E+ + ++ E + Q QE+ E+++ ++++KK R+ ++
Sbjct: 549 QEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 608
Query: 519 EKKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPD 577
E+K ++ ++ + +E ++ +E MQ E K M+E E E+ E +++ P+
Sbjct: 609 EEKMQEQEEKMQEQEEKMWEQEEKMQEQEEK-----MWEQEEKMWEQEEKMWEQQRLPE 662
Score = 39.3 bits (90), Expect = 0.010
Identities = 109/592 (18%), Positives = 227/592 (38%), Gaps = 104/592 (17%)
Query: 18 KEMSLEEPKKMTRED---WRKKKELEEQRKLGNAPAEVDEEGKDINPHIPQYISSVPWYI 74
+E E+ +KM ++ WR+++ L EQ K E +++ +D + W
Sbjct: 354 EEKMWEQEEKMREQEEKMWRQEERLWEQEK---QMREQEQKMRDQEERM--------WEQ 402
Query: 75 DPSKRPTLKHQRPQPEKQKQFSSSGEWYKRGVKENSIITKYRKGACENCGAMTHKKKDCF 134
D R + R Q + +Q E ++ ++E T+ ++ + + ++K
Sbjct: 403 DERLREKEERMREQEKMWEQVEKMRE--EKKMQEQEKKTRDQEEKMQEEERIREREKKMR 460
Query: 135 ERPRRVGAKFTGTNIAPDEHVQPQLMFDYDGKRDRWNGYN-PEEHMKIVEEYAKVDLAKR 193
E + + +E +Q Q ++ + W PE+ K+ E+
Sbjct: 461 EEEETMREQ--------EEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ--------- 503
Query: 194 TLKAQKLQEELASGKLVEQANSPKHQ---WGEEEPNSQMEKDHNSED---EDEDKYADDI 247
+K+QE+ K+ EQ + Q WG+E+ + EK ED E E+K D
Sbjct: 504 ----EKMQEQ--EEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 557
Query: 248 D--------MPGQNFDSKRRITVRNLRIREDIAKYLRNLDPNSAYYDPKTRAMRENPYAN 299
M + + +++ + ++RE+ + +R + + R E
Sbjct: 558 QKMWDQEERMEKKTQEQEKKTWDQEEKMREE--ERMREREKKMREEEEMMREQEEKMQEQ 615
Query: 300 AGKNPDEVSYAGDNFVRYTGDTISMAQTQLFAWEAYDKGSEVHLQADPTKLELLYKSFKV 359
K ++ + + M + + WE +K E Q P + E L++ K+
Sbjct: 616 EEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ--QRLPEQKEKLWEHEKM 673
Query: 360 KKEDFKEQQKESILEKYGGQEHLDAPPAELLLAQTEDYVEYSRHGTVIKGQERAVACSKY 419
++++ ++Q+E I E QE ++ E + E R ++ +E+ + +
Sbjct: 674 QEQEKMQEQEEKIWE----QEKMEKKTQEQEKKTWDQ--EKMREEESMREREKKM---RE 724
Query: 420 EEDVKIHNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAGKEIVNSEECIINEITGEES 479
EE++ + K E +E+ EE + + EE
Sbjct: 725 EEEMMREQEEKMQEQEEK------------------MQEQEEEMWEQEEKMWEQ---EEK 763
Query: 480 VKKPQTLMEL-----------HQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKA 528
+ + Q L E QEK+ E+++K + +++K R +E+K ++
Sbjct: 764 MWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEK 823
Query: 529 LNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDPM 580
+ +E ++ +E M E K M+ E EE+M+ K + ++ M
Sbjct: 824 MWGQEEKMWGQEEKMWGQEEK-----MWGQEEKMEEKMQGQEEKMREQEEKM 870
Score = 38.5 bits (88), Expect = 0.017
Identities = 95/562 (16%), Positives = 207/562 (36%), Gaps = 71/562 (12%)
Query: 28 MTREDWRKKKELEEQRKLGNAPAEV---------DEEGKDINPHIPQYISSVPWYIDPSK 78
+ E WR+++EL EQ K E ++EGK + W +
Sbjct: 270 LQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGK------MREQEEKMWRQEKRL 323
Query: 79 RPTLKHQRPQPEKQKQFSSSGEWYKRGVKENSIITKYRKGACENCGAMTHKKKDCFERPR 138
R K R Q ++ ++ E ++ ++ + + + E M +++ +E+ +
Sbjct: 324 REQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEK 383
Query: 139 RVGAKFTGTNIAPDEHVQPQLMFDYDGKRDRWNGYNPEEHMKIVEEYAKVDLAKRTLKAQ 198
++ Q Q M D + + + +E ++ EE + + K + +
Sbjct: 384 QM-------------REQEQKMRDQEERM-----WEQDERLREKEERMR-EQEKMWEQVE 424
Query: 199 KLQEELASGKLVEQANSPKHQWGEEEPNSQMEKDHNSEDEDEDKYADDIDMPGQNFDSKR 258
K++EE + ++ + + EEE + EK E+E + + + +N +
Sbjct: 425 KMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 484
Query: 259 RITVRNLRIREDIAKYLRNLDPNSAYYDPKTRAMRENPYANAGKNPDEVSYAGDNFVRYT 318
+ R+ E K + K + E + K D+ G +
Sbjct: 485 EKEWQQQRLPEQKEKL---------WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR 535
Query: 319 GDTISMAQTQLFAWEAYDKGSEVHLQADPTKLELLYKSFKVKKEDFKEQQKESILEKYGG 378
+ + + Q++ E + E + ++E + + K D +E+ +E E+
Sbjct: 536 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREE--ERMRE 593
Query: 379 QEHLDAPPAELLLAQTEDYVEYSRHGTVIKGQERAVACSKYEEDVKIHNHTHIWGSYWKE 438
+E E++ Q E E K QE+ + EE ++ W++
Sbjct: 594 REKKMREEEEMMREQEEKMQEQEE-----KMQEQEEKMWEQEEKMQEQEE-----KMWEQ 643
Query: 439 GRWGYKCCHSFFKYSYCTGEAGKEIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEK 498
++ ++ + K E + Q M+ +EK+ E++
Sbjct: 644 EEKMWEQEEKMWEQQRLPEQKEK-------------LWEHEKMQEQEKMQEQEEKIWEQE 690
Query: 499 KKKKKKKKKHRKS-SSDSDDEEKKHEKLKKALNAEEARLLHVKETMQIDERK--RPYNSM 555
K +KK +++ +K+ + EE+ + +K + EE + +E MQ E K M
Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEM 750
Query: 556 YETREPTEEEMEAYRMKRQRPD 577
+E E E+ E +++ P+
Sbjct: 751 WEQEEKMWEQEEKMWEQQRLPE 772
Score = 37.7 bits (86), Expect = 0.030
Identities = 51/284 (17%), Positives = 114/284 (40%), Gaps = 26/284 (9%)
Query: 18 KEMSLEEPKKMTRED--WRKKKELEEQRKLGNAPAEVDEEGKDINPHIPQYISSVPWYID 75
++M +E K +E+ W +++++ EQ++L ++ E K Q W +
Sbjct: 631 EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQE 690
Query: 76 PSKRPTLKHQRP--QPEKQKQFSSSGEWYKRGVKENSIITKYRKGACENCGAMTHKKKDC 133
++ T + ++ EK ++ S E K+ +E ++ + + E M ++++
Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEM 750
Query: 134 FERPRRVGAKFTGTNIAPDEHVQPQLMFDYDGKRDRWNGYNPEEHMKIVEEYAKVDLAKR 193
+E+ ++ + +E + Q + K W +E KI E+ K+ +
Sbjct: 751 WEQEEKMWEQ--------EEKMWEQQRLP-EQKEKLWEHEKMQEQEKIWEQEEKMRDQEE 801
Query: 194 TLKAQKLQEELASGKLVEQANSPKHQWGEEEPNSQMEKDHNSEDEDEDKYADDIDMPGQN 253
++ Q EE G+ + + WG+EE ++E + + M GQ
Sbjct: 802 KMRGQ---EEKMRGQEEKMRGQEEKMWGQEE---------KMWGQEEKMWGQEEKMWGQE 849
Query: 254 FDSKRRITVRNLRIREDIAKYLRNLDPNSAYYDPKTRAMRENPY 297
+ ++ + ++RE K +R + + K R E Y
Sbjct: 850 EKMEEKMQGQEEKMREQEEK-MRGQEEKMREQEEKMRGQEEKIY 892
Score = 33.9 bits (76), Expect = 0.43
Identities = 23/97 (23%), Positives = 51/97 (52%), Gaps = 3/97 (3%)
Query: 484 QTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETM 543
Q M +E+L+E++KK +K+++K + ++E K + ++ + +E RL ++
Sbjct: 271 QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLR--EQEK 328
Query: 544 QIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDPM 580
++ E+++ E RE EE+M+ K ++ M
Sbjct: 329 ELREQEKELREQKELRE-QEEQMQEQEEKMWEQEEKM 364
Score = 29.6 bits (65), Expect = 8.1
Identities = 23/92 (25%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 483 PQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKET 542
PQ QE++ ++++ ++++KK RK +E+K + ++ L +E ++ +E
Sbjct: 263 PQVQTNTLQEEMWRQEEELREQEKKIRK-------QEEKMWRQEERLREQEGKMREQEEK 315
Query: 543 MQIDERKRPYNSMYETREPTEEEMEAYRMKRQ 574
M E KR E RE +E E ++ Q
Sbjct: 316 MWRQE-KRLREQEKELREQEKELREQKELREQ 346
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 43.5 bits (101), Expect = 5e-04
Identities = 30/123 (24%), Positives = 63/123 (51%), Gaps = 10/123 (8%)
Query: 461 KEIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEK 520
+E + +E I E EE +++ + +M+ +EK+ E++ K +++ K ++ +E+
Sbjct: 438 EEKIREQEKKIRE--QEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEE 495
Query: 521 KHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETRE---PTEEEMEAYRMKRQRPD 577
K + +K + +E ++ +E MQ E K M+E E EE+M+ K +R +
Sbjct: 496 KIREQEKKIREQEEKIREQEEMMQEQEEK-----MWEQEEKMCEQEEKMQEQEEKMRRQE 550
Query: 578 DPM 580
+ M
Sbjct: 551 EKM 553
Score = 40.4 bits (93), Expect = 0.005
Identities = 21/101 (20%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
EE +++ + +M+ +EK+ E+++K +++++ ++ +E+K + +K + +E ++
Sbjct: 396 EEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKI 455
Query: 537 LHVKETMQIDERK--RPYNSMYETREPTEEEMEAYRMKRQR 575
+E MQ E K M E +E+ E R + ++
Sbjct: 456 REQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEK 496
Score = 37.4 bits (85), Expect = 0.039
Identities = 43/194 (22%), Positives = 89/194 (45%), Gaps = 23/194 (11%)
Query: 358 KVKKEDFKEQQKESIL----EKYGGQEHLDAPPAELLLAQTEDYVEYSRHGTVIKGQERA 413
K+++++ K +++E ++ EK G QE E + Q E + R I+ QE+
Sbjct: 391 KIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE---KMRRQEEKIREQEKK 447
Query: 414 VACSKYEEDVKIHNHTHIWGSYW-KEGRWGYKCCHSFFKYSYCTGEAGK--EIVNSEECI 470
+ E++ KI + K G K C K + + E + +E
Sbjct: 448 IR----EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKK 503
Query: 471 INEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALN 530
I E EE +++ + +M+ +EK+ E+++K ++++K ++E+K + ++ +
Sbjct: 504 IRE--QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK-------MQEQEEKMRRQEEKMR 554
Query: 531 AEEARLLHVKETMQ 544
+E RL +E MQ
Sbjct: 555 EQEVRLRQQEEKMQ 568
Score = 36.6 bits (83), Expect = 0.066
Identities = 58/302 (19%), Positives = 126/302 (41%), Gaps = 42/302 (13%)
Query: 301 GKNPDEVSYAGDNFVRYTGD---TISMAQTQLFAWEAYDKGSEVHLQADPTKLELLYKSF 357
G+ D +S D++ ++ G+ +S TQ + Y + E+ + D LEL +
Sbjct: 146 GEARDLISRLHDSW-KFAGELEQALSAVATQKKKADRYIE--ELTKERDALSLELYRNTI 202
Query: 358 ---KVKKEDFKEQQKESILEKYGGQEHLDAPP-------AELLLAQTEDYVEYSRHGTVI 407
++K+++ K Q+K ++E + L+ A+LLL Q + E
Sbjct: 203 TDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADH----- 257
Query: 408 KGQERAVACSKYEEDVKIHNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAGKEIVNSE 467
G+E +K + V+ + + +E W + E ++I E
Sbjct: 258 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW---------RQEEKIQEREEKIQEQE 308
Query: 468 ECIINEITGEESVKKPQTLMELHQEKL---------KEEKKKKKKKKKKHRKSSSDSDDE 518
E I + EE +++ + +M +EK+ KEEK ++ ++K ++ + +++
Sbjct: 309 EKIREQ---EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEK 365
Query: 519 EKKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDD 578
++ EK+++ +E ++ +I E++ E + EE+M K ++
Sbjct: 366 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEE 425
Query: 579 PM 580
M
Sbjct: 426 EM 427
Score = 35.0 bits (79), Expect = 0.19
Identities = 26/110 (23%), Positives = 55/110 (50%), Gaps = 7/110 (6%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKK-KKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEAR 535
EE +++ + M +EK++E++KK +++++K + + EEK E+ K + +EA+
Sbjct: 424 EEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGK-MCEQEAK 482
Query: 536 LLHVKETM-----QIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDPM 580
+ +E M +I E+++ E EE M+ K ++ M
Sbjct: 483 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKM 532
Score = 34.7 bits (78), Expect = 0.25
Identities = 27/117 (23%), Positives = 61/117 (52%), Gaps = 14/117 (11%)
Query: 461 KEIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEK 520
+E++ +E I E+ EE + + + + E +EK +EE+K ++++K++ ++E
Sbjct: 336 EEMMWEKEEKIREL--EEKMHEQEKIRE-QEEKRQEEEKIREQEKRQ---------EQEA 383
Query: 521 KHEKLKKALNAEEARLLHVKETMQIDERK--RPYNSMYETREPTEEEMEAYRMKRQR 575
K + ++ + +E ++ +E MQ E K M+E E +E+ E R + ++
Sbjct: 384 KMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEK 440
Score = 33.9 bits (76), Expect = 0.43
Identities = 24/112 (21%), Positives = 52/112 (46%), Gaps = 8/112 (7%)
Query: 471 INEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHE------K 524
+ E E+ + Q +EK++E++K+++++ K R+ + EEK E +
Sbjct: 349 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQE 408
Query: 525 LKKALNAEEARLLHVKETMQIDERK--RPYNSMYETREPTEEEMEAYRMKRQ 574
++ + +E ++ +E MQ E K R + E + E+ E R + +
Sbjct: 409 QEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 460
Score = 32.0 bits (71), Expect = 1.6
Identities = 17/96 (17%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
Query: 473 EITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAE 532
+I +E ++ + M +EK++E+++K +++++ ++ ++E+K + ++ + +
Sbjct: 371 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQ 430
Query: 533 EARLLHVKETMQIDERK-RPYNSMYETREPTEEEME 567
E ++ +E ++ E+K R +E +E E
Sbjct: 431 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE 466
Score = 31.6 bits (70), Expect = 2.1
Identities = 23/101 (22%), Positives = 50/101 (49%), Gaps = 4/101 (3%)
Query: 477 EESVKKPQTLMELHQEKLK-EEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEAR 535
EE + + + M+ +EK++ +E+K ++++KK + + EE E+ +K + +E +
Sbjct: 417 EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK-MGEQEGK 475
Query: 536 LLHVKETMQIDERK--RPYNSMYETREPTEEEMEAYRMKRQ 574
+ + MQ E K R + E + E+ E R + +
Sbjct: 476 MCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 516
Score = 30.4 bits (67), Expect = 4.7
Identities = 18/98 (18%), Positives = 44/98 (44%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
EE +++ + E + ++E+K +++++K + + EEK E+ +K EE
Sbjct: 369 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQ 428
Query: 537 LHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQ 574
++ + +E+ R +E E E +++
Sbjct: 429 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE 466
>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
sapiens]
Length = 1268
Score = 43.5 bits (101), Expect = 5e-04
Identities = 28/114 (24%), Positives = 65/114 (57%), Gaps = 9/114 (7%)
Query: 462 EIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKK 521
++ N E +E + +++ Q E H+ +L E++K+ +++K+ R+ ++++++
Sbjct: 358 QLANKER---SEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRL---EEQQRR 411
Query: 522 HEKLKKALNAEEARLLHVKETMQIDE-RKRPYNSMYETREPTEEEMEAYRMKRQ 574
++L+K E+ R H +E M+ +E R+R + R+ EE+ +A R++RQ
Sbjct: 412 EKELRKQQEREQRR--HYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQ 463
>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
sapiens]
Length = 1276
Score = 43.5 bits (101), Expect = 5e-04
Identities = 28/114 (24%), Positives = 65/114 (57%), Gaps = 9/114 (7%)
Query: 462 EIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKK 521
++ N E +E + +++ Q E H+ +L E++K+ +++K+ R+ ++++++
Sbjct: 358 QLANKER---SEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRL---EEQQRR 411
Query: 522 HEKLKKALNAEEARLLHVKETMQIDE-RKRPYNSMYETREPTEEEMEAYRMKRQ 574
++L+K E+ R H +E M+ +E R+R + R+ EE+ +A R++RQ
Sbjct: 412 EKELRKQQEREQRR--HYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQ 463
>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
sapiens]
Length = 1323
Score = 43.5 bits (101), Expect = 5e-04
Identities = 28/114 (24%), Positives = 65/114 (57%), Gaps = 9/114 (7%)
Query: 462 EIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKK 521
++ N E +E + +++ Q E H+ +L E++K+ +++K+ R+ ++++++
Sbjct: 358 QLANKER---SEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRL---EEQQRR 411
Query: 522 HEKLKKALNAEEARLLHVKETMQIDE-RKRPYNSMYETREPTEEEMEAYRMKRQ 574
++L+K E+ R H +E M+ +E R+R + R+ EE+ +A R++RQ
Sbjct: 412 EKELRKQQEREQRR--HYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQ 463
>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
sapiens]
Length = 1331
Score = 43.5 bits (101), Expect = 5e-04
Identities = 28/114 (24%), Positives = 65/114 (57%), Gaps = 9/114 (7%)
Query: 462 EIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKK 521
++ N E +E + +++ Q E H+ +L E++K+ +++K+ R+ ++++++
Sbjct: 358 QLANKER---SEALRRQQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRL---EEQQRR 411
Query: 522 HEKLKKALNAEEARLLHVKETMQIDE-RKRPYNSMYETREPTEEEMEAYRMKRQ 574
++L+K E+ R H +E M+ +E R+R + R+ EE+ +A R++RQ
Sbjct: 412 EKELRKQQEREQRR--HYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQ 463
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 43.5 bits (101), Expect = 5e-04
Identities = 109/596 (18%), Positives = 228/596 (38%), Gaps = 105/596 (17%)
Query: 26 KKMTREDWRKKKELEEQRKLGNAPAEVDEEGKDINPHIPQYISSVPWYIDPSKRPTLKHQ 85
+++ R + R++K L+E E K+ +P I S+P + +
Sbjct: 98 ERLARREERRQKRLQEAL----------ERQKEFDPTITDASLSLP----SRRMQNDTAE 143
Query: 86 RPQPEKQKQFSSSGEWYKRGVKENSIITK-YRKG----ACENCGAMTHKKKDCFERPRRV 140
EK+++ S E Y+ ++E +TK Y+K A EN K+++ E+P+R
Sbjct: 144 NETTEKEEKSESRQERYE--IEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRG 201
Query: 141 GAKFTGTNIAPDEHV-----QPQLMFDYDGK---------RDRWNGYNPEEHMKIVEEYA 186
+ +E + +M +G+ +R G + H + +EE
Sbjct: 202 SIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEED 261
Query: 187 K--VDLAKRTLKAQ-----------KLQEELASGKLVEQANSPKHQWGEEEPNSQMEKDH 233
K + + L+A+ K+ +E A + E+A + + + E E +M ++
Sbjct: 262 KERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEE 321
Query: 234 NSEDEDEDKYADDIDMPGQNF----DSKRRITVRNLRIREDIAKYLRNLDPNSAYYDPKT 289
E+ + ++ + + ++R RI+E+ + A + K
Sbjct: 322 KRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKA 381
Query: 290 RAMRENPYANAGKNPDEVSYAGDNFVRYTGDTISMAQTQLFAWEAYDKGSEVHLQADPTK 349
+ + K +E +A + G+ + Q W K E LQ K
Sbjct: 382 KVEEQK----RNKQLEEKKHAMQE-TKIKGEKVE--QKIEGKWVNEKKAQEDKLQTAVLK 434
Query: 350 LELLYKSFKVKKEDFKEQQKESILEKYGGQEHL---DAPPAELLLAQTEDYVEYSRHGTV 406
+ K KV+ + K Q+ + +K ++ D P E + + +++ + T
Sbjct: 435 KQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKE----EVKSFMDRKKGFTE 490
Query: 407 IKGQERAVACSKYEEDVKIHNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAGKEIVNS 466
+K Q + H H ++ + G G+ V++
Sbjct: 491 VKSQNG---------EFMTHKLKHTENTFSRPG--------------------GRASVDT 521
Query: 467 EECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLK 526
+E G V+ + L EL + + + E ++ +K K+K ++++ + ++ +KK E+ +
Sbjct: 522 KEA-----EGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERR 576
Query: 527 KALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQR-PDDPMA 581
K L EE R ++ + D + R +E E KRQ+ P+D ++
Sbjct: 577 KVLEEEEQR----RKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLS 628
Score = 31.2 bits (69), Expect = 2.8
Identities = 25/122 (20%), Positives = 55/122 (45%), Gaps = 6/122 (4%)
Query: 465 NSEECIINEITGE---ESVKKPQTLMELHQEKLKEEKKKKKKKKK-KHRKSSSDSDDEEK 520
N E ++ E T E E+V ++ E+ K+E+++++ + H + + D E
Sbjct: 206 NQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERA 265
Query: 521 KHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDPM 580
+ E+ + L AEE + ++ +I + + + + E EA +R R ++
Sbjct: 266 EAERAR--LEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKR 323
Query: 581 AS 582
A+
Sbjct: 324 AA 325
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 42.4 bits (98), Expect = 0.001
Identities = 32/111 (28%), Positives = 52/111 (46%), Gaps = 6/111 (5%)
Query: 475 TGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDE-----EKKHEKLKKAL 529
T EE KK + + +K +++K K+K KK S SDSD E E + KKA
Sbjct: 177 TSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAK 236
Query: 530 NAEEARLLHVKETMQIDERK-RPYNSMYETREPTEEEMEAYRMKRQRPDDP 579
E+ + K+ + +K R +S ++E EE +E R + ++P
Sbjct: 237 KKEKKKKHRSKKYKKKRSKKSRKESSDSSSKESQEEFLENPWKDRTKAEEP 287
>gi|8923271 coiled-coil domain containing 49 [Homo sapiens]
Length = 425
Score = 42.4 bits (98), Expect = 0.001
Identities = 29/77 (37%), Positives = 42/77 (54%), Gaps = 10/77 (12%)
Query: 461 KEIVNSEECIINEITGEESVKKPQTLMELH---QEKLKEEKKKKKKKKKKHRKSSSD--- 514
KE E + N + +KK + L+++ +EK K+++KKKK KK KHR SSSD
Sbjct: 145 KEEEKKREVLNNPV----KMKKIKELLQMSLEKKEKKKKKEKKKKHKKHKHRSSSSDRSS 200
Query: 515 SDDEEKKHEKLKKALNA 531
S+DE KK N+
Sbjct: 201 SEDEHSAGRSQKKMANS 217
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/99 (25%), Positives = 54/99 (54%), Gaps = 8/99 (8%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
EE +++ + E QEK+ ++KK +++ +K R+ + +E+K +L++ + +E +L
Sbjct: 394 EEKIREQE---EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 537 LHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQR 575
V+E MQ +E K M E E + + E + + ++
Sbjct: 451 REVEEKMQEEEEK-----MQEQEEKIQRQEEKIQEQEEK 484
Score = 40.8 bits (94), Expect = 0.003
Identities = 31/107 (28%), Positives = 56/107 (52%), Gaps = 9/107 (8%)
Query: 477 EESVKKPQTLMELHQEKLKE-EKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEAR 535
EE +++ + +M+ +EKL+E E+K +++++K + EEK E+ +K E +
Sbjct: 433 EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE--K 490
Query: 536 LLHVKETMQIDERK--RPYNSMYETREPTEEEMEAYRMKRQRPDDPM 580
LL +E + E K R M+E E +E+ E K QR ++ M
Sbjct: 491 LLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEE----KMQRQEEKM 533
Score = 38.1 bits (87), Expect = 0.023
Identities = 80/427 (18%), Positives = 173/427 (40%), Gaps = 44/427 (10%)
Query: 173 YNPEEHMKIVEEYAKVDLAKRTLKAQKLQEELASGKLVEQ--ANSPKHQWGEEEPNSQME 230
++P + + +E + +D L+ Q GK E+ A+ Q E E +
Sbjct: 17 FDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENR 76
Query: 231 KDHNSEDEDEDKYADDIDMPGQNFDSKRRIT--VRNLRIRED--IAKYLRNLDPNSAYYD 286
K ++ DED ++ + Q +S +R+T + + ED ++ +N D + +
Sbjct: 77 KRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFK 136
Query: 287 PKTRAMRENPYANAGKNPDEVSYA--GDNFVRYTGDTISMAQTQLFAWEAYDKGSEVHL- 343
+ M E Y + + + G+ + + + +T F A G+ +
Sbjct: 137 KRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFD-HAVRMGTYIEKL 195
Query: 344 --QADPTKLELLYKSF---KVKKEDFKEQQKESILEKYGGQEHLDAPP-------AELLL 391
+ D LEL + ++K+++ + Q+K ++E + L+ A+LLL
Sbjct: 196 TKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLL 255
Query: 392 AQTEDYVEYSRHGTVIKGQERAVACSKYEEDVKIHNHTHIWGSYWKEGRWGYKCCHSFFK 451
Q + VE R G+E +K + V+ + ++ +E W + +
Sbjct: 256 PQQQLQVEADR-----LGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQE 310
Query: 452 YSYCTGEAGKEIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKS 511
C +E I E EE + + + M +EK++E++ K ++++K R+
Sbjct: 311 EKMC----------EQELKIRE--QEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQ 358
Query: 512 SSDSDDEEKKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRM 571
++E+K + ++ + ++ ++ +E M E K + E E +E+M
Sbjct: 359 EEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK-----IREQEEKRQEKMWRQEK 413
Query: 572 KRQRPDD 578
K + D+
Sbjct: 414 KMREQDE 420
Score = 35.4 bits (80), Expect = 0.15
Identities = 23/106 (21%), Positives = 55/106 (51%), Gaps = 6/106 (5%)
Query: 477 EESVKKP-QTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLK---KALNAE 532
EE +++ + + E +E ++E+K +++++K+ K ++ EK++ + + +
Sbjct: 373 EEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQ 432
Query: 533 EARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDD 578
E ++ ++E MQ E K + E + EE+M+ K QR ++
Sbjct: 433 EEKIRELEEMMQDQEEK--LREVEEKMQEEEEKMQEQEEKIQRQEE 476
Score = 34.3 bits (77), Expect = 0.33
Identities = 25/110 (22%), Positives = 58/110 (52%), Gaps = 4/110 (3%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
EE +++ + ++ +EK++E+++K +++K ++ + EEK + +K EE ++
Sbjct: 461 EEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEE-KM 519
Query: 537 LHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDPMASFLGQ 586
+E MQ E K + ++ EE+M+ ++ Q ++ + LGQ
Sbjct: 520 QEQEEKMQRQEEKMREQEVRLWQQ--EEKMQEQEVRLQELEERLGK-LGQ 566
Score = 34.3 bits (77), Expect = 0.33
Identities = 22/90 (24%), Positives = 49/90 (54%), Gaps = 4/90 (4%)
Query: 458 EAGKEIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDD 517
E ++I EE I + EE + + L++ +EK+ E+++K ++++K + +
Sbjct: 466 EQEEKIQRQEEKIQEQ---EEKTWRQEKLLK-QEEKIWEQEEKMWRQEEKMWEQEEKMQE 521
Query: 518 EEKKHEKLKKALNAEEARLLHVKETMQIDE 547
+E+K ++ ++ + +E RL +E MQ E
Sbjct: 522 QEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/99 (25%), Positives = 54/99 (54%), Gaps = 8/99 (8%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
EE +++ + E QEK+ ++KK +++ +K R+ + +E+K +L++ + +E +L
Sbjct: 394 EEKIREQE---EKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 537 LHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQR 575
V+E MQ +E K M E E + + E + + ++
Sbjct: 451 REVEEKMQEEEEK-----MQEQEEKIQRQEEKIQEQEEK 484
Score = 40.8 bits (94), Expect = 0.003
Identities = 31/107 (28%), Positives = 56/107 (52%), Gaps = 9/107 (8%)
Query: 477 EESVKKPQTLMELHQEKLKE-EKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEAR 535
EE +++ + +M+ +EKL+E E+K +++++K + EEK E+ +K E +
Sbjct: 433 EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE--K 490
Query: 536 LLHVKETMQIDERK--RPYNSMYETREPTEEEMEAYRMKRQRPDDPM 580
LL +E + E K R M+E E +E+ E K QR ++ M
Sbjct: 491 LLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEE----KMQRQEEKM 533
Score = 38.1 bits (87), Expect = 0.023
Identities = 80/427 (18%), Positives = 173/427 (40%), Gaps = 44/427 (10%)
Query: 173 YNPEEHMKIVEEYAKVDLAKRTLKAQKLQEELASGKLVEQ--ANSPKHQWGEEEPNSQME 230
++P + + +E + +D L+ Q GK E+ A+ Q E E +
Sbjct: 17 FDPTKSPVLSDEDSDLDFHINKLEQQSKVRNKGHGKPREKSIADEKFFQLSEMEAYLENR 76
Query: 231 KDHNSEDEDEDKYADDIDMPGQNFDSKRRIT--VRNLRIRED--IAKYLRNLDPNSAYYD 286
K ++ DED ++ + Q +S +R+T + + ED ++ +N D + +
Sbjct: 77 KRRGTKRWDEDDDLEESEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFK 136
Query: 287 PKTRAMRENPYANAGKNPDEVSYA--GDNFVRYTGDTISMAQTQLFAWEAYDKGSEVHL- 343
+ M E Y + + + G+ + + + +T F A G+ +
Sbjct: 137 KRQEKMNEKNYTFRKRVVIKKPWLRLGEVTAQKRPENSLLEETLHFD-HAVRMGTYIEKL 195
Query: 344 --QADPTKLELLYKSF---KVKKEDFKEQQKESILEKYGGQEHLDAPP-------AELLL 391
+ D LEL + ++K+++ + Q+K ++E + L+ A+LLL
Sbjct: 196 TKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLL 255
Query: 392 AQTEDYVEYSRHGTVIKGQERAVACSKYEEDVKIHNHTHIWGSYWKEGRWGYKCCHSFFK 451
Q + VE R G+E +K + V+ + ++ +E W + +
Sbjct: 256 PQQQLQVEADR-----LGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQE 310
Query: 452 YSYCTGEAGKEIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKS 511
C +E I E EE + + + M +EK++E++ K ++++K R+
Sbjct: 311 EKMC----------EQELKIRE--QEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQ 358
Query: 512 SSDSDDEEKKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRM 571
++E+K + ++ + ++ ++ +E M E K + E E +E+M
Sbjct: 359 EEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEK-----IREQEEKRQEKMWRQEK 413
Query: 572 KRQRPDD 578
K + D+
Sbjct: 414 KMREQDE 420
Score = 35.4 bits (80), Expect = 0.15
Identities = 23/106 (21%), Positives = 55/106 (51%), Gaps = 6/106 (5%)
Query: 477 EESVKKP-QTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLK---KALNAE 532
EE +++ + + E +E ++E+K +++++K+ K ++ EK++ + + +
Sbjct: 373 EEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQ 432
Query: 533 EARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDD 578
E ++ ++E MQ E K + E + EE+M+ K QR ++
Sbjct: 433 EEKIRELEEMMQDQEEK--LREVEEKMQEEEEKMQEQEEKIQRQEE 476
Score = 34.3 bits (77), Expect = 0.33
Identities = 25/110 (22%), Positives = 58/110 (52%), Gaps = 4/110 (3%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
EE +++ + ++ +EK++E+++K +++K ++ + EEK + +K EE ++
Sbjct: 461 EEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEE-KM 519
Query: 537 LHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDPMASFLGQ 586
+E MQ E K + ++ EE+M+ ++ Q ++ + LGQ
Sbjct: 520 QEQEEKMQRQEEKMREQEVRLWQQ--EEKMQEQEVRLQELEERLGK-LGQ 566
Score = 34.3 bits (77), Expect = 0.33
Identities = 22/90 (24%), Positives = 49/90 (54%), Gaps = 4/90 (4%)
Query: 458 EAGKEIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDD 517
E ++I EE I + EE + + L++ +EK+ E+++K ++++K + +
Sbjct: 466 EQEEKIQRQEEKIQEQ---EEKTWRQEKLLK-QEEKIWEQEEKMWRQEEKMWEQEEKMQE 521
Query: 518 EEKKHEKLKKALNAEEARLLHVKETMQIDE 547
+E+K ++ ++ + +E RL +E MQ E
Sbjct: 522 QEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 42.0 bits (97), Expect = 0.002
Identities = 79/422 (18%), Positives = 177/422 (41%), Gaps = 45/422 (10%)
Query: 173 YNPEEHMKIVEEYAKVDLAKRTLKAQKLQEELASGKLVEQANSPKHQWGEEEPNSQMEKD 232
+ EE ++ E+ + K + ++L+E+ GK+ EQ + Q E+ + EK+
Sbjct: 237 WRQEEELREQEKKIRKQEEKMWRQEERLREQ--EGKMREQEEKMRRQ---EKRLREQEKE 291
Query: 233 HNSEDEDEDKYADDIDMPGQNFDSKRRITVRNLRIREDIAKYLRNLDPNSAYYDPKTRAM 292
++++ + + Q + + ++ + ++RE K R + + + M
Sbjct: 292 LREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER----LWEQEKQM 347
Query: 293 RENPYANAGKNPDEVSYAGDNFVRYTGDTISMAQTQLFAWEAYDKGSEVHLQADPTKLEL 352
RE ++ +E + D +R + + + Q WE +K E ++
Sbjct: 348 REQEQKM--RDQEERMWEQDERLREKEERM---REQEKMWEQEEKMQEEE------RIRE 396
Query: 353 LYKSFKVKKEDFKEQQKESILEKYGGQEHLDAP-PAELLLAQTEDYVEYSRHGTVIKGQE 411
K + ++E +EQ+++ ++ E + + L Q E E + ++ QE
Sbjct: 397 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK----MQEQE 452
Query: 412 RAVACSKYEEDVKIHNHTHIWGS---YWKEGRWGYKCCHSFFKYSYCTGEAGKEIVNSEE 468
+ +E++ KI + +WG W++ + + ++ + +++ + EE
Sbjct: 453 EKI----WEQEEKIRDQEEMWGQEKKMWRQEKMREQE-DQMWEQEEKMRDQEQKMWDQEE 507
Query: 469 CIINE---ITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKL 525
+ + + +E + Q M +EK++EEKK ++++KK + EE++ +
Sbjct: 508 RMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW--DQEEKMREEERMRER 565
Query: 526 KKALNAEEARLLHVKETMQIDERK--RPYNSMYETREPTEEEMEAY-----RMKRQRPDD 578
+K + EE + +E MQ E K M+E E +E+ E +M Q +D
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED 625
Query: 579 PM 580
M
Sbjct: 626 KM 627
Score = 39.3 bits (90), Expect = 0.010
Identities = 24/103 (23%), Positives = 53/103 (51%), Gaps = 4/103 (3%)
Query: 477 EESVKKPQTLMELHQEKLKE-EKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEAR 535
E+ +++ + +M +EK++E E+K +++++K + + EEK E+ +K EE
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED 625
Query: 536 LLHVKETM---QIDERKRPYNSMYETREPTEEEMEAYRMKRQR 575
+ +E M Q ++ + M+E E E+ E R + ++
Sbjct: 626 KMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEK 668
Score = 38.9 bits (89), Expect = 0.013
Identities = 20/89 (22%), Positives = 48/89 (53%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
EE +++ + M+ +EK++E+++K + +++K R+ +E+K ++ + +E ++
Sbjct: 659 EEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKM 718
Query: 537 LHVKETMQIDERKRPYNSMYETREPTEEE 565
+E + +ER R + R P EE
Sbjct: 719 WGQEEMREKEERIRDQKEKMQERLPEHEE 747
Score = 36.2 bits (82), Expect = 0.086
Identities = 28/126 (22%), Positives = 63/126 (50%), Gaps = 6/126 (4%)
Query: 456 TGEAGKEIVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDS 515
T E K+ + EE ++ EE +++ + M +E ++E+++K +++++K R+
Sbjct: 542 TQEQEKKTWDQEE----KMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM 597
Query: 516 -DDEEKKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQ 574
+ EEK E+ +K EE ++ +E ++ E++ E + EE+M K +
Sbjct: 598 WEQEEKMQEQEEKMWEQEE-KMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR 656
Query: 575 RPDDPM 580
++ M
Sbjct: 657 EQEEKM 662
Score = 36.2 bits (82), Expect = 0.086
Identities = 16/73 (21%), Positives = 42/73 (57%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
EE + + + M+ +EK+ E+++K +++++K R+ +E+K + ++ + +E ++
Sbjct: 631 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKM 690
Query: 537 LHVKETMQIDERK 549
+E M+ E K
Sbjct: 691 REQEEKMRGQEEK 703
Score = 35.8 bits (81), Expect = 0.11
Identities = 22/102 (21%), Positives = 52/102 (50%), Gaps = 3/102 (2%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
EE + + + M +EK++E+++K + +++K R+ +E+K + ++ + +E ++
Sbjct: 645 EEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKM 704
Query: 537 LHVKETMQIDERKR-PYNSMYETREPTEEEMEAYRMKRQRPD 577
+E M E K M E E ++ E +M+ + P+
Sbjct: 705 WGQEEKMWGQEEKMWGQEEMREKEERIRDQKE--KMQERLPE 744
Score = 35.4 bits (80), Expect = 0.15
Identities = 15/73 (20%), Positives = 44/73 (60%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
E+ +++ + +M +EK++E+++K ++++K R+ ++E+K + ++ + +E ++
Sbjct: 624 EDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKM 683
Query: 537 LHVKETMQIDERK 549
+E M+ E K
Sbjct: 684 QGQEEKMREQEEK 696
Score = 34.3 bits (77), Expect = 0.33
Identities = 20/85 (23%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
Query: 484 QTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETM 543
Q M +E+L+E++KK +K+++K + ++E K + ++ + +E RL ++ +
Sbjct: 233 QEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKEL 292
Query: 544 QIDERK-RPYNSMYETREPTEEEME 567
+ E++ R + E E +E+ E
Sbjct: 293 REQEKELREQKKLREQEEQMQEQEE 317
Score = 33.1 bits (74), Expect = 0.73
Identities = 15/73 (20%), Positives = 42/73 (57%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
EE +++ + M +EK++E+++K +++++K + ++E+K + ++ + +E ++
Sbjct: 638 EEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKM 697
Query: 537 LHVKETMQIDERK 549
+E M E K
Sbjct: 698 RGQEEKMWGQEEK 710
Score = 31.6 bits (70), Expect = 2.1
Identities = 23/92 (25%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Query: 483 PQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARLLHVKET 542
PQ QE++ ++++ ++++KK RK +E+K + ++ L +E ++ +E
Sbjct: 225 PQVQTNTLQEEMWRQEEELREQEKKIRK-------QEEKMWRQEERLREQEGKMREQEEK 277
Query: 543 MQIDERKRPYNSMYETREPTEEEMEAYRMKRQ 574
M+ E KR E RE +E E +++ Q
Sbjct: 278 MRRQE-KRLREQEKELREQEKELREQKKLREQ 308
Score = 31.6 bits (70), Expect = 2.1
Identities = 22/106 (20%), Positives = 52/106 (49%), Gaps = 4/106 (3%)
Query: 477 EESVKKPQTLMELHQEKL--KEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEA 534
EE +++ + M +EK+ +EE+ K +++++ + ++E+K + ++ + +E
Sbjct: 601 EEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 660
Query: 535 RLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDPM 580
++ +E MQ E K E + EE+M K + ++ M
Sbjct: 661 KMREQEEKMQGQEEK--MREQEEKMQGQEEKMREQEEKMRGQEEKM 704
Score = 31.2 bits (69), Expect = 2.8
Identities = 20/99 (20%), Positives = 44/99 (44%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
EE ++ + L E ++ K+E+K +++++ + + EEK + K+ E+
Sbjct: 234 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELR 293
Query: 537 LHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQR 575
KE + + + M E E E+ E R + ++
Sbjct: 294 EQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332
>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sapiens]
Length = 2211
Score = 42.0 bits (97), Expect = 0.002
Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 10/107 (9%)
Query: 473 EITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAE 532
++T EE +K + +L Q KE K K ++KKK RK S + D+ E++ + ++E
Sbjct: 907 DLTPEEEARKKKEKDKLRQLLKKERLKAKLQRKKKKRKGSDEEDEGEEEESSSSEESSSE 966
Query: 533 EARLLHVKETMQIDERKRPYN-SMYETREPTEEEMEAYRMKRQRPDD 578
E E M+ +E + + M E E + + EA+R + +D
Sbjct: 967 E-------EEMEEEEEEEEFGPGMQEVIE--QHKFEAHRWLARGKED 1004
Score = 32.0 bits (71), Expect = 1.6
Identities = 22/77 (28%), Positives = 42/77 (54%), Gaps = 4/77 (5%)
Query: 175 PEEHMKIVEEYAKVDLAKRTLKAQKLQEELASGKLVEQANSPKHQWGEEEPNSQMEKDHN 234
PEE + +E K+ ++ LK ++L+ +L K ++ S + GEEE +S E+ +
Sbjct: 910 PEEEARKKKEKDKL---RQLLKKERLKAKLQRKKK-KRKGSDEEDEGEEEESSSSEESSS 965
Query: 235 SEDEDEDKYADDIDMPG 251
E+E E++ ++ PG
Sbjct: 966 EEEEMEEEEEEEEFGPG 982
>gi|18426913 drebrin 1 isoform b [Homo sapiens]
Length = 651
Score = 42.0 bits (97), Expect = 0.002
Identities = 26/110 (23%), Positives = 59/110 (53%), Gaps = 6/110 (5%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
EE K + QE++++E+++++++++++R + + + ++H + ++ L AEEA+
Sbjct: 196 EERKKALDERLRFEQERMEQERQEQEERERRYR----EREQQIEEHRRKQQTLEAEEAKR 251
Query: 537 LHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDPMASFLGQ 586
++++ D R + + E EE A + QRPD+P F Q
Sbjct: 252 RLKEQSIFGDHRDEEEETHMKKSESEVEEAAA--IIAQRPDNPREFFKQQ 299
Score = 31.2 bits (69), Expect = 2.8
Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 11/125 (8%)
Query: 10 NAAPLSGS--KEMSLEEPKKMTRED-WRKKKELEEQRKLGNAPAEVDEEGKDINPHIPQY 66
NA P+ + K + E K++ RE W + K+ EE RK +DE + + Q
Sbjct: 157 NAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQE 216
Query: 67 ISSVPWYIDPSKRPTLKHQRPQPEKQKQFSSSGEWYKRGVKENSIITKYRKGACENCGAM 126
+ +R + Q+ + ++KQ + E KR +KE SI +R E
Sbjct: 217 RQEQE---ERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEE----- 268
Query: 127 THKKK 131
TH KK
Sbjct: 269 THMKK 273
>gi|18426915 drebrin 1 isoform a [Homo sapiens]
Length = 649
Score = 42.0 bits (97), Expect = 0.002
Identities = 26/110 (23%), Positives = 59/110 (53%), Gaps = 6/110 (5%)
Query: 477 EESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKHEKLKKALNAEEARL 536
EE K + QE++++E+++++++++++R + + + ++H + ++ L AEEA+
Sbjct: 194 EERKKALDERLRFEQERMEQERQEQEERERRYR----EREQQIEEHRRKQQTLEAEEAKR 249
Query: 537 LHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDPMASFLGQ 586
++++ D R + + E EE A + QRPD+P F Q
Sbjct: 250 RLKEQSIFGDHRDEEEETHMKKSESEVEEAAA--IIAQRPDNPREFFKQQ 297
Score = 31.2 bits (69), Expect = 2.8
Identities = 34/125 (27%), Positives = 54/125 (43%), Gaps = 11/125 (8%)
Query: 10 NAAPLSGS--KEMSLEEPKKMTRED-WRKKKELEEQRKLGNAPAEVDEEGKDINPHIPQY 66
NA P+ + K + E K++ RE W + K+ EE RK +DE + + Q
Sbjct: 155 NAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQE 214
Query: 67 ISSVPWYIDPSKRPTLKHQRPQPEKQKQFSSSGEWYKRGVKENSIITKYRKGACENCGAM 126
+ +R + Q+ + ++KQ + E KR +KE SI +R E
Sbjct: 215 RQEQE---ERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFGDHRDEEEE----- 266
Query: 127 THKKK 131
TH KK
Sbjct: 267 THMKK 271
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
b [Homo sapiens]
Length = 1524
Score = 42.0 bits (97), Expect = 0.002
Identities = 35/136 (25%), Positives = 58/136 (42%), Gaps = 25/136 (18%)
Query: 474 ITGEESVKKPQTLME------------LHQEKLK----EEKKKKKKKKKKHRKSSSDSDD 517
I+ E++V QTL L QE++K E+ K K++K + +D
Sbjct: 285 ISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKED 344
Query: 518 EEKKHEKLKKALNAEEARLLHVKETMQID---------ERKRPYNSMYETREPTEEEMEA 568
+EKK E+LKK + E + KE ++++ E KR Y + E+ME
Sbjct: 345 KEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMEC 404
Query: 569 YRMKRQRPDDPMASFL 584
+K P+ + L
Sbjct: 405 DDLKELPEPTPVKTRL 420
Score = 30.4 bits (67), Expect = 4.7
Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 9/92 (9%)
Query: 176 EEHMKIVEEYA----KVDLAKRTLKAQKLQEELASGKLVEQANSPKH-QWGEEE----PN 226
E+H K EE A K K + QK++E+ K EQ NS GEEE
Sbjct: 622 EQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFDT 681
Query: 227 SQMEKDHNSEDEDEDKYADDIDMPGQNFDSKR 258
S KD ++ D+D +D D PG + +R
Sbjct: 682 SIESKDTEQKELDQDMVTEDEDDPGSHKRGRR 713
Score = 30.0 bits (66), Expect = 6.2
Identities = 21/117 (17%), Positives = 53/117 (45%), Gaps = 6/117 (5%)
Query: 463 IVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKH 522
+V++ + I + + K+ ++ Q + + E+ + +K+K K ++K
Sbjct: 595 LVSTRDFIEDYVDILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQ 654
Query: 523 EKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDP 579
EKLK+ + + E E + +++ E+++ ++E++ M + DDP
Sbjct: 655 EKLKEDEQRNSTADISIGE-----EEREDFDTSIESKDTEQKELD-QDMVTEDEDDP 705
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform
a [Homo sapiens]
Length = 1556
Score = 42.0 bits (97), Expect = 0.002
Identities = 35/136 (25%), Positives = 58/136 (42%), Gaps = 25/136 (18%)
Query: 474 ITGEESVKKPQTLME------------LHQEKLK----EEKKKKKKKKKKHRKSSSDSDD 517
I+ E++V QTL L QE++K E+ K K++K + +D
Sbjct: 285 ISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKEKED 344
Query: 518 EEKKHEKLKKALNAEEARLLHVKETMQID---------ERKRPYNSMYETREPTEEEMEA 568
+EKK E+LKK + E + KE ++++ E KR Y + E+ME
Sbjct: 345 KEKKREELKKIVEEERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDMEC 404
Query: 569 YRMKRQRPDDPMASFL 584
+K P+ + L
Sbjct: 405 DDLKELPEPTPVKTRL 420
Score = 30.4 bits (67), Expect = 4.7
Identities = 30/92 (32%), Positives = 41/92 (44%), Gaps = 9/92 (9%)
Query: 176 EEHMKIVEEYA----KVDLAKRTLKAQKLQEELASGKLVEQANSPKH-QWGEEE----PN 226
E+H K EE A K K + QK++E+ K EQ NS GEEE
Sbjct: 654 EQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEEREDFDT 713
Query: 227 SQMEKDHNSEDEDEDKYADDIDMPGQNFDSKR 258
S KD ++ D+D +D D PG + +R
Sbjct: 714 SIESKDTEQKELDQDMVTEDEDDPGSHKRGRR 745
Score = 30.0 bits (66), Expect = 6.2
Identities = 21/117 (17%), Positives = 53/117 (45%), Gaps = 6/117 (5%)
Query: 463 IVNSEECIINEITGEESVKKPQTLMELHQEKLKEEKKKKKKKKKKHRKSSSDSDDEEKKH 522
+V++ + I + + K+ ++ Q + + E+ + +K+K K ++K
Sbjct: 627 LVSTRDFIEDYVDILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQ 686
Query: 523 EKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKRQRPDDP 579
EKLK+ + + E E + +++ E+++ ++E++ M + DDP
Sbjct: 687 EKLKEDEQRNSTADISIGE-----EEREDFDTSIESKDTEQKELD-QDMVTEDEDDP 737
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.128 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,052,612
Number of Sequences: 37866
Number of extensions: 1294487
Number of successful extensions: 19088
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 361
Number of HSP's successfully gapped in prelim test: 447
Number of HSP's that attempted gapping in prelim test: 10207
Number of HSP's gapped (non-prelim): 5691
length of query: 586
length of database: 18,247,518
effective HSP length: 108
effective length of query: 478
effective length of database: 14,157,990
effective search space: 6767519220
effective search space used: 6767519220
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.