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Search of human proteins with 27262632
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27262632 neural stem cell-derived dendrite regulator [Homo
sapiens]
(1042 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27262632 neural stem cell-derived dendrite regulator [Homo sa... 2089 0.0
gi|218931251 diacylglycerol lipase, beta isoform 1 [Homo sapiens] 367 e-101
gi|218931253 diacylglycerol lipase, beta isoform 2 [Homo sapiens] 213 6e-55
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 38 0.057
gi|237757346 DDHD domain containing 1 isoform c [Homo sapiens] 37 0.097
gi|237757344 DDHD domain containing 1 isoform b [Homo sapiens] 37 0.097
gi|237757342 DDHD domain containing 1 isoform a [Homo sapiens] 37 0.097
gi|55742730 storkhead box 2 [Homo sapiens] 37 0.097
gi|38373693 Sp3 transcription factor isoform 1 [Homo sapiens] 35 0.28
gi|160948610 E3 ubiquitin-protein ligase UBR3 [Homo sapiens] 35 0.28
gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens] 35 0.37
gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens] 35 0.37
gi|48717234 olfactory receptor, family 9, subfamily A, member 2 ... 34 0.63
gi|172072597 retinoblastoma-like 2 (p130) [Homo sapiens] 33 1.1
gi|239747883 PREDICTED: hypothetical protein [Homo sapiens] 33 1.1
gi|12707580 paired-like homeobox 2b [Homo sapiens] 33 1.1
gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap... 33 1.1
gi|38026934 Rho guanine nucleotide exchange factor (GEF) 11 isof... 33 1.4
gi|7662086 Rho guanine nucleotide exchange factor (GEF) 11 isofo... 33 1.4
gi|238859653 pleckstrin homology domain containing family A memb... 33 1.4
gi|238859651 pleckstrin homology domain containing family A memb... 33 1.4
gi|239753310 PREDICTED: hypothetical protein XP_002345618 [Homo ... 33 1.4
gi|239741764 PREDICTED: hypothetical protein XP_002342289 [Homo ... 33 1.4
gi|140161498 hypothetical protein LOC23281 isoform a [Homo sapiens] 33 1.4
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi... 33 1.8
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi... 33 1.8
gi|22035548 amyloid beta A4 precursor protein-binding, family A,... 33 1.8
gi|157504499 ankyrin repeat domain 47 [Homo sapiens] 33 1.8
gi|33188443 microfilament and actin filament cross-linker protei... 32 2.4
gi|33188445 microfilament and actin filament cross-linker protei... 32 2.4
>gi|27262632 neural stem cell-derived dendrite regulator [Homo
sapiens]
Length = 1042
Score = 2089 bits (5413), Expect = 0.0
Identities = 1042/1042 (100%), Positives = 1042/1042 (100%)
Query: 1 MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLNLVDHGR 60
MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLNLVDHGR
Sbjct: 1 MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLNLVDHGR 60
Query: 61 GYLGILLSCMIAEMAIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVWLT 120
GYLGILLSCMIAEMAIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVWLT
Sbjct: 61 GYLGILLSCMIAEMAIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVWLT 120
Query: 121 QYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTY 180
QYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTY
Sbjct: 121 QYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLRTY 180
Query: 181 NLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGL 240
NLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGL
Sbjct: 181 NLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGL 240
Query: 241 VLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNSQEMLRYKEVCYYMLFAL 300
VLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNSQEMLRYKEVCYYMLFAL
Sbjct: 241 VLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNSQEMLRYKEVCYYMLFAL 300
Query: 301 AAYGWPMYLMRKPACGLCQLARSCSCCLCPARPRFAPGVTIEEDNCCGCNAIAIRRHFLD 360
AAYGWPMYLMRKPACGLCQLARSCSCCLCPARPRFAPGVTIEEDNCCGCNAIAIRRHFLD
Sbjct: 301 AAYGWPMYLMRKPACGLCQLARSCSCCLCPARPRFAPGVTIEEDNCCGCNAIAIRRHFLD 360
Query: 361 ENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVVISIRGTLSPKDALTDLTGDAERLPVE 420
ENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVVISIRGTLSPKDALTDLTGDAERLPVE
Sbjct: 361 ENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVVISIRGTLSPKDALTDLTGDAERLPVE 420
Query: 421 GHHGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFGRDLGRGTKHYGLIVVGHSLGAGTAAI 480
GHHGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFGRDLGRGTKHYGLIVVGHSLGAGTAAI
Sbjct: 421 GHHGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFGRDLGRGTKHYGLIVVGHSLGAGTAAI 480
Query: 481 LSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKEFVTAVVLGKDLVPRIGLSQLEGFRRQ 540
LSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKEFVTAVVLGKDLVPRIGLSQLEGFRRQ
Sbjct: 481 LSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKEFVTAVVLGKDLVPRIGLSQLEGFRRQ 540
Query: 541 LLDVLQRSTKPKWRIIVGATKCIPKSELPEEVEVTTLASTRLWTHPSDLTIALSASTPLY 600
LLDVLQRSTKPKWRIIVGATKCIPKSELPEEVEVTTLASTRLWTHPSDLTIALSASTPLY
Sbjct: 541 LLDVLQRSTKPKWRIIVGATKCIPKSELPEEVEVTTLASTRLWTHPSDLTIALSASTPLY 600
Query: 601 PPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDNKAFNEVIISPAMLHEHLPYVVMEGLN 660
PPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDNKAFNEVIISPAMLHEHLPYVVMEGLN
Sbjct: 601 PPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDNKAFNEVIISPAMLHEHLPYVVMEGLN 660
Query: 661 KVLENYNKGKTALLSAAKVMVSPTEVDLTPELIFQQQPLPTGPPMPTGLALELPTADHRN 720
KVLENYNKGKTALLSAAKVMVSPTEVDLTPELIFQQQPLPTGPPMPTGLALELPTADHRN
Sbjct: 661 KVLENYNKGKTALLSAAKVMVSPTEVDLTPELIFQQQPLPTGPPMPTGLALELPTADHRN 720
Query: 721 SSVRSKSQSEMSLEGFSEGRLLSPVVAAAARQDPVELLLLSTQERLAAELQARRAPLATM 780
SSVRSKSQSEMSLEGFSEGRLLSPVVAAAARQDPVELLLLSTQERLAAELQARRAPLATM
Sbjct: 721 SSVRSKSQSEMSLEGFSEGRLLSPVVAAAARQDPVELLLLSTQERLAAELQARRAPLATM 780
Query: 781 ESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLERDEGHLFYIDPAIPEENPSLSSRTEL 840
ESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLERDEGHLFYIDPAIPEENPSLSSRTEL
Sbjct: 781 ESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLERDEGHLFYIDPAIPEENPSLSSRTEL 840
Query: 841 LAADSLSKHSQDTQPLEAALGSGGVTPERPPSAAANDEEEEVGGGGGGPASRGELALHNG 900
LAADSLSKHSQDTQPLEAALGSGGVTPERPPSAAANDEEEEVGGGGGGPASRGELALHNG
Sbjct: 841 LAADSLSKHSQDTQPLEAALGSGGVTPERPPSAAANDEEEEVGGGGGGPASRGELALHNG 900
Query: 901 RLGDSPSPQVLEFAEFIDSLFNLDSKSSSFQDLYCMVVPESPTSDYAEGPKSPSQQEILL 960
RLGDSPSPQVLEFAEFIDSLFNLDSKSSSFQDLYCMVVPESPTSDYAEGPKSPSQQEILL
Sbjct: 901 RLGDSPSPQVLEFAEFIDSLFNLDSKSSSFQDLYCMVVPESPTSDYAEGPKSPSQQEILL 960
Query: 961 RAQFEPNLVPKPPRLFAGSADPSSGISLSPSFPLSSSGELMDLTPTGLSSQECLAADKIR 1020
RAQFEPNLVPKPPRLFAGSADPSSGISLSPSFPLSSSGELMDLTPTGLSSQECLAADKIR
Sbjct: 961 RAQFEPNLVPKPPRLFAGSADPSSGISLSPSFPLSSSGELMDLTPTGLSSQECLAADKIR 1020
Query: 1021 TSTPTGHGASPAKQDELVISAR 1042
TSTPTGHGASPAKQDELVISAR
Sbjct: 1021 TSTPTGHGASPAKQDELVISAR 1042
>gi|218931251 diacylglycerol lipase, beta isoform 1 [Homo sapiens]
Length = 672
Score = 367 bits (942), Expect = e-101
Identities = 243/714 (34%), Positives = 369/714 (51%), Gaps = 71/714 (9%)
Query: 1 MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLN-LVDHG 59
MPG+V+F RRW++ SDDLV P F ++ W++ ++ L++ C+ L+
Sbjct: 1 MPGMVLFGRRWAIASDDLVFPGFFELVVRVLWWI--GILTLYLMHRGKLDCAGGALLSSY 58
Query: 60 RGYLGILLSCMIAEM-AIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVW 118
L ILL+ +I + AI+ +SMRG I PR SM +LY+RLA+ E ++A +G W
Sbjct: 59 LIVLMILLAVVICTVSAIMCVSMRGTICNPGPRKSMSKLLYIRLALFFPEMVWASLGAAW 118
Query: 119 LTQYYTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQRNLR 178
+ C D T N + VV +W++I + ++++ VFDP G + +
Sbjct: 119 VADG-VQC-DRTVVNGIIATVVVSWIIIAATVVSIIIVFDPLGGKMAPYSSAGPSHLDSH 176
Query: 179 -TYNLRHRLEEGQATSWSRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDII 237
+ L + L+ + W R+K+ CC D A+S A LF+ +F D D+VPSDI
Sbjct: 177 DSSQLLNGLKTAATSVWETRIKLLCCCIGKDDHTRVAFSSTAELFSTYFSDTDLVPSDIA 236
Query: 238 AGLVLLRQRQRAKRNAVLDEANNDILAFLSGMPVTRNTKYLDLKNSQEMLRYKEVCY-YM 296
AGL LL Q+Q RN N + + P + LD + E C+ YM
Sbjct: 237 AGLALLHQQQDNIRN------NQEPAQVVCHAPGSSQEADLDAE--------LENCHHYM 282
Query: 297 LFALAAYGWPMYLMRKPACGLCQLARSCSCCLCPARPRFAPGVTIEEDNCCGCNAIAIRR 356
FA AAYGWP+Y+ R P GLC++ C C +R V ++ NC
Sbjct: 283 QFAAAAYGWPLYIYRNPLTGLCRIGGDC----CRSRTTDYDLVGGDQLNC---------- 328
Query: 357 HFLD----ENMTAVDIVYTSCHDAVYETPFYVAVDHDKKKVVISIRGTLSPKDALTDLTG 412
HF + D ++ S HD VYE PF VA+DH K+ VV+++RGT+S +D LTDL+
Sbjct: 329 HFGSILHTTGLQYRDFIHVSFHDKVYELPFLVALDHRKESVVVAVRGTMSLQDVLTDLSA 388
Query: 413 DAERLPVEGHHGTWLGHKGMVLSAEYIKKKLEQEMVLSQAFGRDLGRGTKHYGLIVVGHS 472
++E L VE L HKG+ +A Y+ ++L + +LSQAF Y L++VGHS
Sbjct: 389 ESEVLDVECEVQDRLAHKGISQAARYVYQRLINDGILSQAFSI-----APEYRLVIVGHS 443
Query: 473 LGAGTAAILSFLLRPQYPTLKCFAYSPPGGLLSEDAMEYSKEFVTAVVLGKDLVPRIGLS 532
LG G AA+L+ +LR YP ++C+A+SPP GL S+ EYS+ F+ ++VLGKD++PR+ ++
Sbjct: 444 LGGGAAALLATMLRAAYPQVRCYAFSPPRGLWSKALQEYSQSFIVSLVLGKDVIPRLSVT 503
Query: 533 QLEGFRRQLLDVLQRSTKPKWRIIV---------GATKCIPKSELPEEVEVTT---LAST 580
LE +R++L V+ KPK++I++ G +P + EV T L
Sbjct: 504 NLEDLKRRILRVVAHCNKPKYKILLHGLWYELFGGNPNNLPTELDGGDQEVLTQPLLGEQ 563
Query: 581 RLWTHPSDLTIALSAS--------TPLYPPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWG 632
L T S S S PLYPPGRIIH+ + + CC Y A W
Sbjct: 564 SLLTRWSPAYSFSSDSPLDSSPKYPPLYPPGRIIHLQEEGASGRFGCCSAAH--YSAKWS 621
Query: 633 DNKAFNEVIISPAMLHEHLPYVVMEGLNKVLENYNKGKTALLSAAKVMVSPTEV 686
F++++I P ML +H+P ++M L+ V+ + + A +S VS +V
Sbjct: 622 HEAEFSKILIGPKMLTDHMPDILMRALDSVVSD----RAACVSCPAQGVSSVDV 671
>gi|218931253 diacylglycerol lipase, beta isoform 2 [Homo sapiens]
Length = 543
Score = 213 bits (543), Expect = 6e-55
Identities = 126/340 (37%), Positives = 191/340 (56%), Gaps = 31/340 (9%)
Query: 367 DIVYTSCHDAVYETPFYVAVDHDKKKVVISIRGTLSPKDALTDLTGDAERLPVEGHHGTW 426
D ++ S HD VYE PF VA+DH K+ VV+++RGT+S +D LTDL+ ++E L VE
Sbjct: 214 DFIHVSFHDKVYELPFLVALDHRKESVVVAVRGTMSLQDVLTDLSAESEVLDVECEVQDR 273
Query: 427 LGHKGMVLSAEYIKKKLEQEMVLSQAFGRDLGRGTKHYGLIVVGHSLGAGTAAILSFLLR 486
L HKG+ +A Y+ ++L + +LSQAF Y L++VGHSLG G AA+L+ +LR
Sbjct: 274 LAHKGISQAARYVYQRLINDGILSQAFSI-----APEYRLVIVGHSLGGGAAALLATMLR 328
Query: 487 PQYPTLKCFAYSPPGGLLSEDAMEYSKEFVTAVVLGKDLVPRIGLSQLEGFRRQLLDVLQ 546
YP ++C+A+SPP GL S+ EYS+ F+ ++VLGKD++PR+ ++ LE +R++L V+
Sbjct: 329 AAYPQVRCYAFSPPRGLWSKALQEYSQSFIVSLVLGKDVIPRLSVTNLEDLKRRILRVVA 388
Query: 547 RSTKPKWRIIV---------GATKCIPKSELPEEVEVTT---LASTRLWTHPSDLTIALS 594
KPK++I++ G +P + EV T L L T S S
Sbjct: 389 HCNKPKYKILLHGLWYELFGGNPNNLPTELDGGDQEVLTQPLLGEQSLLTRWSPAYSFSS 448
Query: 595 AS--------TPLYPPGRIIHVVHNHPAEQCCCCEQEEPTYFAIWGDNKAFNEVIISPAM 646
S PLYPPGRIIH+ + + CC Y A W F++++I P M
Sbjct: 449 DSPLDSSPKYPPLYPPGRIIHLQEEGASGRFGCCSAAH--YSAKWSHEAEFSKILIGPKM 506
Query: 647 LHEHLPYVVMEGLNKVLENYNKGKTALLSAAKVMVSPTEV 686
L +H+P ++M L+ V+ + + A +S VS +V
Sbjct: 507 LTDHMPDILMRALDSVVSD----RAACVSCPAQGVSSVDV 542
Score = 74.3 bits (181), Expect = 5e-13
Identities = 44/121 (36%), Positives = 70/121 (57%), Gaps = 4/121 (3%)
Query: 1 MPGIVVFRRRWSVGSDDLVLPAIFLFLLHTTWFVILSVVLFGLVYNPHEACSLN-LVDHG 59
MPG+V+F RRW++ SDDLV P F ++ W++ ++ L++ C+ L+
Sbjct: 1 MPGMVLFGRRWAIASDDLVFPGFFELVVRVLWWI--GILTLYLMHRGKLDCAGGALLSSY 58
Query: 60 RGYLGILLSCMIAEM-AIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVW 118
L ILL+ +I + AI+ +SMRG I PR SM +LY+RLA+ E ++A +G W
Sbjct: 59 LIVLMILLAVVICTVSAIMCVSMRGTICNPGPRKSMSKLLYIRLALFFPEMVWASLGAAW 118
Query: 119 L 119
+
Sbjct: 119 V 119
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 37.7 bits (86), Expect = 0.057
Identities = 94/409 (22%), Positives = 139/409 (33%), Gaps = 69/409 (16%)
Query: 674 LSAAKVMVSPTEVDL----TP-----ELIFQQQPLPTGPPMPTGLALELPTADHRNSSVR 724
L++ + V+P+ V+L TP L + P TG A++ +SS
Sbjct: 2270 LASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRT 2329
Query: 725 SKSQSEMSLEGFSEGRLLSPVVAAAARQDPVELLLLSTQERLA-----AELQARRAPLAT 779
++ + +L G +PV A +R T R+A A L + R PL+
Sbjct: 2330 PQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSA 2389
Query: 780 MESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLERDEGHLFYIDPAIPEENPSLSSRTE 839
E +S S D RS R+ +PS + E PS SSR
Sbjct: 2390 YERVSGRTSPPLLDRARS---RTPPSAPSQSRMTS--------------ERAPSPSSRMG 2432
Query: 840 LLAADSLSKHSQDT--QPLEAALGSGGVTPERPPSAAANDEEEEVGGGGGGPASRGELAL 897
+ SL +QD P+ +A + A + G +S G+
Sbjct: 2433 QAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGD--- 2489
Query: 898 HNGRL------------GDSPS------PQVL-------EFAEFIDSLFNLDSKSSSFQD 932
HNG L G+ P+ P L E S + S SSS
Sbjct: 2490 HNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSS 2549
Query: 933 LYCMVVPESPTSDYAEGPKSPSQQEILLRAQFEPNLVPK-------PPRLFAGSADPSSG 985
S +SD +EG P Q E+ L+ P PK PP S
Sbjct: 2550 SSSSSSSGSSSSD-SEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSS 2608
Query: 986 ISLSPSFPLSSSGELMDLTPTGLSSQECLAADKIRTSTPTGHGASPAKQ 1034
S S S SSS + + SS ++ +S+ + A P Q
Sbjct: 2609 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ 2657
>gi|237757346 DDHD domain containing 1 isoform c [Homo sapiens]
Length = 900
Score = 37.0 bits (84), Expect = 0.097
Identities = 31/98 (31%), Positives = 41/98 (41%), Gaps = 20/98 (20%)
Query: 803 IRGSPSLHAVLERDE-GHLFYIDPAIPEENPSLSSRTELLAADSLSKHSQDTQPLEAALG 861
+RG P LH D+ H +DP + +EN SS + SL +S E G
Sbjct: 59 LRGEPGLHLAPGTDDHNHHLALDPCLSDENYDFSSAE---SGSSLRYYS------EGESG 109
Query: 862 SGGVT-----PERPPSAAANDEEEEVGGGGGGPASRGE 894
GG + P++PP N GGGG S GE
Sbjct: 110 GGGSSLSLHPPQQPPLVPTNS-----GGGGATGGSPGE 142
>gi|237757344 DDHD domain containing 1 isoform b [Homo sapiens]
Length = 879
Score = 37.0 bits (84), Expect = 0.097
Identities = 31/98 (31%), Positives = 41/98 (41%), Gaps = 20/98 (20%)
Query: 803 IRGSPSLHAVLERDE-GHLFYIDPAIPEENPSLSSRTELLAADSLSKHSQDTQPLEAALG 861
+RG P LH D+ H +DP + +EN SS + SL +S E G
Sbjct: 59 LRGEPGLHLAPGTDDHNHHLALDPCLSDENYDFSSAE---SGSSLRYYS------EGESG 109
Query: 862 SGGVT-----PERPPSAAANDEEEEVGGGGGGPASRGE 894
GG + P++PP N GGGG S GE
Sbjct: 110 GGGSSLSLHPPQQPPLVPTNS-----GGGGATGGSPGE 142
>gi|237757342 DDHD domain containing 1 isoform a [Homo sapiens]
Length = 872
Score = 37.0 bits (84), Expect = 0.097
Identities = 31/98 (31%), Positives = 41/98 (41%), Gaps = 20/98 (20%)
Query: 803 IRGSPSLHAVLERDE-GHLFYIDPAIPEENPSLSSRTELLAADSLSKHSQDTQPLEAALG 861
+RG P LH D+ H +DP + +EN SS + SL +S E G
Sbjct: 59 LRGEPGLHLAPGTDDHNHHLALDPCLSDENYDFSSAE---SGSSLRYYS------EGESG 109
Query: 862 SGGVT-----PERPPSAAANDEEEEVGGGGGGPASRGE 894
GG + P++PP N GGGG S GE
Sbjct: 110 GGGSSLSLHPPQQPPLVPTNS-----GGGGATGGSPGE 142
>gi|55742730 storkhead box 2 [Homo sapiens]
Length = 926
Score = 37.0 bits (84), Expect = 0.097
Identities = 44/149 (29%), Positives = 65/149 (43%), Gaps = 23/149 (15%)
Query: 835 SSRTELLAADSLSKHSQDTQPLEAALGSGGVTP---ERPPSAA--ANDEEEEVGGGGGGP 889
SS T L A L K+ +D L A G ++P + P S+ +EE G GGGP
Sbjct: 606 SSETVLTAPSPLGKNKEDHDTLTLAEGVKKLSPSDRQVPHSSREPVGHKEESPKGPGGGP 665
Query: 890 ASRGELA--LHNGRL----GDSPSPQVLEFAEFIDSLFNLDSKSSSFQDLYCMV----VP 939
A+ G +A + NGRL G PS +D + SK + F+ L+ +
Sbjct: 666 AASGGVAEGIANGRLVQHHGAEPSS--------LDKRKEIFSKDTLFKPLHSTLSVNSYH 717
Query: 940 ESPTSDYAEGPKSPSQQEILLRAQFEPNL 968
+S S PK+P+ + EP+L
Sbjct: 718 KSSLSLLKSHPKTPADTLPGRCEKLEPSL 746
>gi|38373693 Sp3 transcription factor isoform 1 [Homo sapiens]
Length = 781
Score = 35.4 bits (80), Expect = 0.28
Identities = 22/59 (37%), Positives = 31/59 (52%), Gaps = 3/59 (5%)
Query: 850 SQDTQPLEAALGSGGVTPERPPSAAANDEEEEVGGGGGGPASRGELA-LHNGRLGDSPS 907
+QDTQP AL + + PPS D+EEE G PA+ G L + +LG +P+
Sbjct: 51 AQDTQPSPLALLAATCSKIGPPS--PGDDEEEAAAAAGAPAAAGATGDLASAQLGGAPN 107
>gi|160948610 E3 ubiquitin-protein ligase UBR3 [Homo sapiens]
Length = 1888
Score = 35.4 bits (80), Expect = 0.28
Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 4/76 (5%)
Query: 825 PAIPEENPSL---SSRTELLAADSLSKHSQDTQPLEAALGSGGVTPERPPSAAANDEEEE 881
P +P +L ++ L AA S + + L+A L ++ ERP +AAA E+
Sbjct: 17 PELPAPGLALDKAATAAHLKAALSRPDNRAGAEELQALL-ERVLSAERPLAAAAGGEDAA 75
Query: 882 VGGGGGGPASRGELAL 897
GGGGGP + E AL
Sbjct: 76 AAGGGGGPGAAEEEAL 91
>gi|164565368 TBC1 domain family, member 14 isoform a [Homo sapiens]
Length = 693
Score = 35.0 bits (79), Expect = 0.37
Identities = 40/158 (25%), Positives = 62/158 (39%), Gaps = 27/158 (17%)
Query: 675 SAAKVMVSPTEVDLTPELIFQQQ-PLPTGPPMPTGLALELPTADHRNSSVRSKSQSEMSL 733
SA V ++ DL PE FQ LP+ P P++ R SVR S +
Sbjct: 82 SAVHVRRKQSDSDLIPERAFQSACALPSCAP-------PAPSSTEREQSVRKSSTFPRT- 133
Query: 734 EGFSEGRLLSPVVAAAARQDPVEL-------------LLLSTQERLAAELQARRAPLATM 780
G+ +L SP A R D V + L +S ++ L + + + + T+
Sbjct: 134 -GYDSVKLYSPTSKALTRSDDVSVCSVSSLGTELSTTLSVSNEDILDLVVTSSSSAIVTL 192
Query: 781 ESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLERDEG 818
E+ D + F + S + RG V E +EG
Sbjct: 193 ENDDDPQ----FTNVTLSSIKETRGLHQQDCVHEAEEG 226
>gi|164565366 TBC1 domain family, member 14 isoform a [Homo sapiens]
Length = 693
Score = 35.0 bits (79), Expect = 0.37
Identities = 40/158 (25%), Positives = 62/158 (39%), Gaps = 27/158 (17%)
Query: 675 SAAKVMVSPTEVDLTPELIFQQQ-PLPTGPPMPTGLALELPTADHRNSSVRSKSQSEMSL 733
SA V ++ DL PE FQ LP+ P P++ R SVR S +
Sbjct: 82 SAVHVRRKQSDSDLIPERAFQSACALPSCAP-------PAPSSTEREQSVRKSSTFPRT- 133
Query: 734 EGFSEGRLLSPVVAAAARQDPVEL-------------LLLSTQERLAAELQARRAPLATM 780
G+ +L SP A R D V + L +S ++ L + + + + T+
Sbjct: 134 -GYDSVKLYSPTSKALTRSDDVSVCSVSSLGTELSTTLSVSNEDILDLVVTSSSSAIVTL 192
Query: 781 ESLSDTESLYSFDSRRSSGFRSIRGSPSLHAVLERDEG 818
E+ D + F + S + RG V E +EG
Sbjct: 193 ENDDDPQ----FTNVTLSSIKETRGLHQQDCVHEAEEG 226
>gi|48717234 olfactory receptor, family 9, subfamily A, member 2
[Homo sapiens]
Length = 310
Score = 34.3 bits (77), Expect = 0.63
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 9/102 (8%)
Query: 63 LGILLSCMIAEMAIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVWLTQY 122
L IL++ +I M ++W G+L+ R + + + + +EF A++G++ + +Y
Sbjct: 68 LEILVTTIIVPM-MLW-----GLLFLGCRQYLSLHVSLNFSCGTMEF--ALLGVMAVDRY 119
Query: 123 YTSCNDLTAKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTF 164
CN L N+ + C WVVI+S L P TF
Sbjct: 120 VAVCNPLRY-NIIMNSSTCIWVVIVSWVFGFLSEIWPIYATF 160
>gi|172072597 retinoblastoma-like 2 (p130) [Homo sapiens]
Length = 1139
Score = 33.5 bits (75), Expect = 1.1
Identities = 21/58 (36%), Positives = 29/58 (50%), Gaps = 10/58 (17%)
Query: 867 PERPPSAAANDEEEEVGGGGGGPASRGELALHNGRLGDSPSPQVLEFAEFIDSLFNLD 924
P PP+AAA+DEEEE G A E SP+PQ+ + + + S N+D
Sbjct: 12 PPPPPAAAASDEEEEDDGEAEDAAPPAE----------SPTPQIQQRFDELCSRLNMD 59
>gi|239747883 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 33.5 bits (75), Expect = 1.1
Identities = 29/123 (23%), Positives = 47/123 (38%), Gaps = 24/123 (19%)
Query: 860 LGSGGVTPERPPSAAAN-------DEEEEVGGGGGGPASRGELALHNGRLGDSPSPQVLE 912
LG G ++P + +E E + G GP G LG P V +
Sbjct: 11 LGDVGAKAQKPGGGRRDSIVPRTWEETEGIPKGPSGP---------QGPLGYPGPPGVKD 61
Query: 913 FAEFIDSLFNLDSKSSSFQDLYCMVVPESPTSDYAEGPKSPSQQEILLRAQFEPNLVPKP 972
I LD + + P++P+ A G + P ++ + P+L+P+P
Sbjct: 62 SKPMICIALALDH--------HTLYTPQAPSPATATGIRQPHSASLVPLSPLGPDLIPRP 113
Query: 973 PRL 975
PRL
Sbjct: 114 PRL 116
>gi|12707580 paired-like homeobox 2b [Homo sapiens]
Length = 314
Score = 33.5 bits (75), Expect = 1.1
Identities = 20/50 (40%), Positives = 24/50 (48%), Gaps = 8/50 (16%)
Query: 844 DSLSKHSQDTQPLEAALGSGGVTPERPPSAAANDEEEEVGGGGGGPASRG 893
D SK ++ T P + G G P PS AN GGGGGGP+ G
Sbjct: 181 DDESKEAKSTDP--DSTGGPGPNPNPTPSCGAN------GGGGGGPSPAG 222
>gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo
sapiens]
Length = 735
Score = 33.5 bits (75), Expect = 1.1
Identities = 19/57 (33%), Positives = 24/57 (42%), Gaps = 2/57 (3%)
Query: 939 PESPTSDYA--EGPKSPSQQEILLRAQFEPNLVPKPPRLFAGSADPSSGISLSPSFP 993
P++P A EGP SP R + +L P R G A P+ SL P P
Sbjct: 45 PQAPEGSQAGAEGPSSPEASRSPARGAYLQSLEPSSRRWVLGGAKPAEDTSLGPGVP 101
>gi|38026934 Rho guanine nucleotide exchange factor (GEF) 11 isoform 2
[Homo sapiens]
Length = 1562
Score = 33.1 bits (74), Expect = 1.4
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 939 PESPTSDYAEGPKSPSQQEILLRAQFEPNLVPKPPRLFAGSADPSSGISLSPSFPLSSSG 998
P ++D++E P SP Q + L Q EP P+L G+ DP PS L G
Sbjct: 1409 PPDSSTDHSEAPMSPPQPDSLPAGQTEPQ-----PQLQGGNDDPRRPSRSPPSLALRDVG 1463
>gi|7662086 Rho guanine nucleotide exchange factor (GEF) 11 isoform 1
[Homo sapiens]
Length = 1522
Score = 33.1 bits (74), Expect = 1.4
Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 939 PESPTSDYAEGPKSPSQQEILLRAQFEPNLVPKPPRLFAGSADPSSGISLSPSFPLSSSG 998
P ++D++E P SP Q + L Q EP P+L G+ DP PS L G
Sbjct: 1369 PPDSSTDHSEAPMSPPQPDSLPAGQTEPQ-----PQLQGGNDDPRRPSRSPPSLALRDVG 1423
>gi|238859653 pleckstrin homology domain containing family A member
4 isoform 2 [Homo sapiens]
Length = 583
Score = 33.1 bits (74), Expect = 1.4
Identities = 39/127 (30%), Positives = 55/127 (43%), Gaps = 18/127 (14%)
Query: 830 ENPSLSSRTELLAADSLSKHSQDTQPLEAALGSGGVTPERPPSAAANDEEEEVGGGGGGP 889
E+P + RT +LAAD+L + L A + G +P S A E GG GG P
Sbjct: 124 EHPGM--RTYVLAADTLEDLRGWLRALGRASRAEGDDYGQPRSPARPQPGEGPGGPGGPP 181
Query: 890 -ASRGELALHNGRLGDSPS----------PQVLEFAEFIDSLFNLDSKSSSFQDLYC-MV 937
SRGE GR+ +SP P++L + D L + + DL+ +
Sbjct: 182 EVSRGE----EGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSGLQMRRARSPDLFTPLS 237
Query: 938 VPESPTS 944
P SP S
Sbjct: 238 RPPSPLS 244
>gi|238859651 pleckstrin homology domain containing family A member
4 isoform 1 [Homo sapiens]
Length = 779
Score = 33.1 bits (74), Expect = 1.4
Identities = 39/127 (30%), Positives = 55/127 (43%), Gaps = 18/127 (14%)
Query: 830 ENPSLSSRTELLAADSLSKHSQDTQPLEAALGSGGVTPERPPSAAANDEEEEVGGGGGGP 889
E+P + RT +LAAD+L + L A + G +P S A E GG GG P
Sbjct: 124 EHPGM--RTYVLAADTLEDLRGWLRALGRASRAEGDDYGQPRSPARPQPGEGPGGPGGPP 181
Query: 890 -ASRGELALHNGRLGDSPS----------PQVLEFAEFIDSLFNLDSKSSSFQDLYC-MV 937
SRGE GR+ +SP P++L + D L + + DL+ +
Sbjct: 182 EVSRGE----EGRISESPEVTRLSRGRGRPRLLTPSPTTDLHSGLQMRRARSPDLFTPLS 237
Query: 938 VPESPTS 944
P SP S
Sbjct: 238 RPPSPLS 244
>gi|239753310 PREDICTED: hypothetical protein XP_002345618 [Homo
sapiens]
Length = 415
Score = 33.1 bits (74), Expect = 1.4
Identities = 13/44 (29%), Positives = 25/44 (56%)
Query: 932 DLYCMVVPESPTSDYAEGPKSPSQQEILLRAQFEPNLVPKPPRL 975
D + + P++P+ A G + P ++ + P+L+P+PPRL
Sbjct: 243 DHHTLYTPQAPSPATATGIRQPHSASLVPLSPLGPDLIPRPPRL 286
>gi|239741764 PREDICTED: hypothetical protein XP_002342289 [Homo
sapiens]
Length = 433
Score = 33.1 bits (74), Expect = 1.4
Identities = 13/44 (29%), Positives = 25/44 (56%)
Query: 932 DLYCMVVPESPTSDYAEGPKSPSQQEILLRAQFEPNLVPKPPRL 975
D + + P++P+ A G + P ++ + P+L+P+PPRL
Sbjct: 243 DHHTLYTPQAPSPATATGIRQPHSASLVPLSPLGPDLIPRPPRL 286
>gi|140161498 hypothetical protein LOC23281 isoform a [Homo sapiens]
Length = 1379
Score = 33.1 bits (74), Expect = 1.4
Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 13/128 (10%)
Query: 765 RLAAELQARRAPLATMESLSDT-ESLYSFDSRRSSGFRSIRGSPSLHAVLERDEGHLFYI 823
RL++ +Q T+E +D+ ++ S S +R++ SL + +RD I
Sbjct: 109 RLSSTIQRELNEEHTVERGTDSLQTTRSIQGPSLSSWRNVMSEASLDVLAKRDAE----I 164
Query: 824 DPAIPEENPSLSSRTELLAADSLSKHSQDTQPLEAALGSGGVTPERPPSAAANDEEE--E 881
+P++ + + E L SL + S AA+GS +TP+ P + + E +
Sbjct: 165 PRHVPKDKLAKTLDNEELRRHSLERASSSV----AAVGS--LTPQHPQPLSLDSREARGQ 218
Query: 882 VGGGGGGP 889
+ GGG GP
Sbjct: 219 IPGGGEGP 226
>gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapiens]
Length = 306
Score = 32.7 bits (73), Expect = 1.8
Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 5/80 (6%)
Query: 952 SPSQQEILLRAQFEPNLVPKPPRLFAGSADPSSGISLSPSFPLSSSGELMDLTPTGLSSQ 1011
+PS Q IL R+ P L P P S P+ S +P+ SS+ L + L+ Q
Sbjct: 27 TPSSQPILTRSS-TPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPQ 85
Query: 1012 ECLAADKIRTSTPTGHGASP 1031
L R+STPT +SP
Sbjct: 86 PILT----RSSTPTLTPSSP 101
>gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapiens]
Length = 306
Score = 32.7 bits (73), Expect = 1.8
Identities = 27/80 (33%), Positives = 37/80 (46%), Gaps = 5/80 (6%)
Query: 952 SPSQQEILLRAQFEPNLVPKPPRLFAGSADPSSGISLSPSFPLSSSGELMDLTPTGLSSQ 1011
+PS Q IL R+ P L P P S P+ S +P+ SS+ L + L+ Q
Sbjct: 27 TPSSQPILTRSS-TPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPQ 85
Query: 1012 ECLAADKIRTSTPTGHGASP 1031
L R+STPT +SP
Sbjct: 86 PILT----RSSTPTLTPSSP 101
>gi|22035548 amyloid beta A4 precursor protein-binding, family A,
member 1 [Homo sapiens]
Length = 837
Score = 32.7 bits (73), Expect = 1.8
Identities = 44/179 (24%), Positives = 72/179 (40%), Gaps = 24/179 (13%)
Query: 823 IDPAIPEENPSLSSRTELLAADSLSKHSQDTQPLEAALGSGGVTPERPPSAAANDEEEEV 882
ID + E S+SS++ AA+ + + QD LE G P+ P A ++ V
Sbjct: 270 IDQIVAEVKQSMSSQSLDKAAEDMPEAEQD---LERPPTPAGGRPDSPGLQAPAGQQRAV 326
Query: 883 GGGGGGPASRGELALHNGRLGDSPSPQVLEFAEFIDSLFNLDSKSSSFQDLYCMVVPESP 942
G GGG A + ++ D+ S + + E I+ + K+ + + Y
Sbjct: 327 GPAGGGEAGQ----RYSKEKRDAISLAIKDIKEAIEEV-----KTRTIRSPY-------- 369
Query: 943 TSDYAEGPKSPSQQEILLRAQFEPNLVPKPPRLFAGSADP----SSGISLSPSFPLSSS 997
T D + P +Q+I + GS+ P SS SL PS P+ +S
Sbjct: 370 TPDEPKEPIWVMRQDISPTRDCDDQRPMDGDSPSPGSSSPLGAESSSTSLHPSDPVEAS 428
>gi|157504499 ankyrin repeat domain 47 [Homo sapiens]
Length = 821
Score = 32.7 bits (73), Expect = 1.8
Identities = 41/191 (21%), Positives = 70/191 (36%), Gaps = 6/191 (3%)
Query: 707 TGLALELPTADHRNSSV-RSKSQSEMSLEGFSEGRLLSPVVAAAARQDPVELLLLSTQER 765
T L LP A R + R+ + + + GRL A A ++ +E
Sbjct: 341 TEALLGLPAAAERELELLRASLEHQRGVSELLRGRLRELEEAREAAEEAAAGARAQLREA 400
Query: 766 LAAELQARRAPLATMESLSDTESLYSFDSRRS-SGFRSIRGSPSLHAVLERDEGHLFYID 824
+ A ES ++ SL S S G R++ + L +++++ +G
Sbjct: 401 TTQTPWSCAEKAAQTESPAEAPSLTQESSPGSMDGDRAVAPAGILKSIMKKRDG----TP 456
Query: 825 PAIPEENPSLSSRTELLAADSLSKHSQDTQPLEAALGSGGVTPERPPSAAANDEEEEVGG 884
A P P +L + S S+D + +GG P S + +D
Sbjct: 457 GAQPSSGPKSLQFVGVLNGEYESSSSEDASDSDGDSENGGAEPPGSSSGSGDDSGGGSDS 516
Query: 885 GGGGPASRGEL 895
G GP S G++
Sbjct: 517 GTPGPPSGGDI 527
>gi|33188443 microfilament and actin filament cross-linker protein
isoform b [Homo sapiens]
Length = 5938
Score = 32.3 bits (72), Expect = 2.4
Identities = 21/56 (37%), Positives = 28/56 (50%), Gaps = 4/56 (7%)
Query: 980 ADPSSGISLSPSFPLSSSGELMDLTPTGLSSQECLAADKIRTSTPTGHGASPAKQD 1035
A P+SG + PS S +L TPT SS+ LA D +S+P GA + D
Sbjct: 5803 ATPASGTKVIPS----SGSKLKRPTPTFHSSRTSLAGDTSNSSSPASTGAKTNRAD 5854
>gi|33188445 microfilament and actin filament cross-linker protein
isoform a [Homo sapiens]
Length = 5430
Score = 32.3 bits (72), Expect = 2.4
Identities = 21/56 (37%), Positives = 28/56 (50%), Gaps = 4/56 (7%)
Query: 980 ADPSSGISLSPSFPLSSSGELMDLTPTGLSSQECLAADKIRTSTPTGHGASPAKQD 1035
A P+SG + PS S +L TPT SS+ LA D +S+P GA + D
Sbjct: 5295 ATPASGTKVIPS----SGSKLKRPTPTFHSSRTSLAGDTSNSSSPASTGAKTNRAD 5346
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,300,788
Number of Sequences: 37866
Number of extensions: 2088581
Number of successful extensions: 8092
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 65
Number of HSP's that attempted gapping in prelim test: 7985
Number of HSP's gapped (non-prelim): 156
length of query: 1042
length of database: 18,247,518
effective HSP length: 112
effective length of query: 930
effective length of database: 14,006,526
effective search space: 13026069180
effective search space used: 13026069180
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.