Guide to the Human Genome
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Search of human proteins with 254039600

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|254039600 F-box and leucine-rich repeat protein 17 [Homo
sapiens]
         (303 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|254039600 F-box and leucine-rich repeat protein 17 [Homo sapi...   614   e-176
gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]   111   9e-25
gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]      95   9e-20
gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]     93   3e-19
gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]    90   2e-18
gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1 ...    82   6e-16
gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2 ...    76   4e-14
gi|164663798 antagonist of mitotic exit network 1 homolog [Homo ...    74   2e-13
gi|190194416 F-box and leucine-rich repeat protein 15 [Homo sapi...    66   3e-11
gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens]     63   3e-10
gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]    59   4e-09
gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens]     48   9e-06
gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens]     48   9e-06
gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]    41   0.001
gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [...    41   0.001
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    40   0.003
gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [...    40   0.003
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami...    37   0.022
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam...    37   0.022
gi|28827813 NLR family, pyrin domain containing 14 [Homo sapiens]      36   0.048
gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens]            35   0.11 
gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens]     34   0.18 
gi|16306584 F-box and leucine-rich repeat protein 3 [Homo sapiens]     33   0.24 
gi|116268109 nucleotide-binding oligomerization domains 27 [Homo...    33   0.41 
gi|55742693 zyg-11 homolog B [Homo sapiens]                            32   0.53 
gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [H...    32   0.91 
gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [H...    32   0.91 
gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [H...    32   0.91 
gi|239754160 PREDICTED: similar to hCG1980490 [Homo sapiens]           31   1.5  
gi|239748674 PREDICTED: similar to hCG1980490 [Homo sapiens]           31   1.5  

>gi|254039600 F-box and leucine-rich repeat protein 17 [Homo
           sapiens]
          Length = 303

 Score =  614 bits (1584), Expect = e-176
 Identities = 303/303 (100%), Positives = 303/303 (100%)

Query: 1   MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60
           MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ
Sbjct: 1   MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60

Query: 61  LGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPEL 120
           LGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPEL
Sbjct: 61  LGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPEL 120

Query: 121 QYVGFMGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWI 180
           QYVGFMGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWI
Sbjct: 121 QYVGFMGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWI 180

Query: 181 INDRCVEVIAKEGQNLKELYLVSCKITDYALIAIGRYSMTIETVDVGWCKEITDQGATLI 240
           INDRCVEVIAKEGQNLKELYLVSCKITDYALIAIGRYSMTIETVDVGWCKEITDQGATLI
Sbjct: 181 INDRCVEVIAKEGQNLKELYLVSCKITDYALIAIGRYSMTIETVDVGWCKEITDQGATLI 240

Query: 241 AQSSKSLRYLGLMRCDKVNEVTVEQLVQQYPHITFSTVLQDCKRTLERAYQMGWTPNMSA 300
           AQSSKSLRYLGLMRCDKVNEVTVEQLVQQYPHITFSTVLQDCKRTLERAYQMGWTPNMSA
Sbjct: 241 AQSSKSLRYLGLMRCDKVNEVTVEQLVQQYPHITFSTVLQDCKRTLERAYQMGWTPNMSA 300

Query: 301 ASS 303
           ASS
Sbjct: 301 ASS 303


>gi|22748931 F-box and leucine-rich repeat protein 14 [Homo sapiens]
          Length = 418

 Score =  111 bits (277), Expect = 9e-25
 Identities = 74/277 (26%), Positives = 142/277 (51%), Gaps = 9/277 (3%)

Query: 1   MSDNGVCVLAFKCPGLLR-YTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLK 59
           ++DNG+     +  G LR      CKQ++D+S+  +A +   L+ + +G    +T+ GL 
Sbjct: 103 LTDNGLGHAFVQEIGSLRALNLSLCKQITDSSLGRIAQYLKGLEVLELGGCSNITNTGLL 162

Query: 60  QLGSKCRELKDIHFGQCYKISDEGMIVIA-------KGCLKLQRIYMQENKLVTDQSVKA 112
            +    + LK ++   C  +SD G+  +A       +GCL L+++ +Q+ + +TD S+K 
Sbjct: 163 LIAWGLQRLKSLNLRSCRHLSDVGIGHLAGMTRSAAEGCLGLEQLTLQDCQKLTDLSLKH 222

Query: 113 FAEHCPELQYVGFMGCS-VTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLS 171
            +     L+ +    C  ++  G++HL+ + +L SL+LR    + +  +M +      LS
Sbjct: 223 ISRGLTGLRLLNLSFCGGISDAGLLHLSHMGSLRSLNLRSCDNISDTGIMHLAMGSLRLS 282

Query: 172 SLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCKITDYALIAIGRYSMTIETVDVGWCKE 231
            L++     + D+ +  IA+    LK L L SC I+D  +  + R    + T+++G C  
Sbjct: 283 GLDVSFCDKVGDQSLAYIAQGLDGLKSLSLCSCHISDDGINRMVRQMHGLRTLNIGQCVR 342

Query: 232 ITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVEQLVQ 268
           ITD+G  LIA+    L  + L  C ++ +  +E++ Q
Sbjct: 343 ITDKGLELIAEHLSQLTGIDLYGCTRITKRGLERITQ 379


>gi|6912466 F-box and leucine-rich repeat protein 7 [Homo sapiens]
          Length = 491

 Score = 94.7 bits (234), Expect = 9e-20
 Identities = 71/277 (25%), Positives = 125/277 (45%), Gaps = 15/277 (5%)

Query: 1   MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLT------ 54
           ++D G+  +A  CP L R     C  +S+ ++  V S CP L+ + V    K+T      
Sbjct: 199 LTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLDVSGCSKVTCISLTR 258

Query: 55  --DEGLKQLGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKA 112
                L  L  K   ++ +    C+ + DEG+  IA  C +L  +Y++    +TD+ ++ 
Sbjct: 259 EASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRY 318

Query: 113 FAEHCPELQYVGFMGCS-VTSKGVIHLTKLRN-LSSLDLRHITELDNETVMEIVKRCKNL 170
              +C  ++ +    C  V+  G+  + KL + L  L + H   + +  +  + K C  L
Sbjct: 319 LVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKL 378

Query: 171 SSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCK-ITDYALIAIGRYSMTIETVDVGWC 229
             LN      I D  VE +AK    LK L +  C  ++D  L  +      ++ + +  C
Sbjct: 379 RYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKSC 438

Query: 230 KEITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVEQL 266
           + IT QG  ++A +   L+ L +  C    EV+VE L
Sbjct: 439 ESITGQGLQIVAANCFDLQTLNVQDC----EVSVEAL 471



 Score = 82.4 bits (202), Expect = 4e-16
 Identities = 55/196 (28%), Positives = 100/196 (51%), Gaps = 2/196 (1%)

Query: 24  CKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEG 83
           C  L D  +  +A+HC  L  +++    +LTDEGL+ L   C  +K++    C  +SD G
Sbjct: 282 CFVLEDEGLHTIAAHCTQLTHLYLRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFG 341

Query: 84  MIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGC-SVTSKGVIHLTK-L 141
           +  IAK   +L+ + +     VTD  ++  A++C +L+Y+   GC  +T  GV +L K  
Sbjct: 342 LREIAKLESRLRYLSIAHCGRVTDVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNC 401

Query: 142 RNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYL 201
             L SLD+     + +  +  +   C NL  L+L     I  + ++++A    +L+ L +
Sbjct: 402 TKLKSLDIGKCPLVSDTGLECLALNCFNLKRLSLKSCESITGQGLQIVAANCFDLQTLNV 461

Query: 202 VSCKITDYALIAIGRY 217
             C+++  AL  + R+
Sbjct: 462 QDCEVSVEALRFVKRH 477



 Score = 80.9 bits (198), Expect = 1e-15
 Identities = 59/239 (24%), Positives = 109/239 (45%), Gaps = 11/239 (4%)

Query: 39  CPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIY 98
           C +L+ V V    +LTD GL  +   C EL+ +    CY IS+E +  +   C  L+ + 
Sbjct: 185 CLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLD 244

Query: 99  MQENKLVT------DQSVKAFAEHCPE--LQYVGFMGCSVTSKGVIH--LTKLRNLSSLD 148
           +     VT      + S+K    H  +  ++Y+    C V     +H        L+ L 
Sbjct: 245 VSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLY 304

Query: 149 LRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSC-KIT 207
           LR    L +E +  +V  C ++  L++     ++D  +  IAK    L+ L +  C ++T
Sbjct: 305 LRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVT 364

Query: 208 DYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVEQL 266
           D  +  + +Y   +  ++   C+ ITD G   +A++   L+ L + +C  V++  +E L
Sbjct: 365 DVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAKNCTKLKSLDIGKCPLVSDTGLECL 423



 Score = 76.6 bits (187), Expect = 2e-14
 Identities = 51/215 (23%), Positives = 101/215 (46%), Gaps = 11/215 (5%)

Query: 65  CRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVG 124
           C  L+ +    C +++D G+  IA+ C +L+R+ +     +++++V      CP L+++ 
Sbjct: 185 CLMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNLEHLD 244

Query: 125 FMGCS------VTSKGVIHLTKLR----NLSSLDLRHITELDNETVMEIVKRCKNLSSLN 174
             GCS      +T +  I L+ L     ++  LD+     L++E +  I   C  L+ L 
Sbjct: 245 VSGCSKVTCISLTREASIKLSPLHGKQISIRYLDMTDCFVLEDEGLHTIAAHCTQLTHLY 304

Query: 175 LCLNWIINDRCVEVIAKEGQNLKELYLVSCK-ITDYALIAIGRYSMTIETVDVGWCKEIT 233
           L     + D  +  +     ++KEL +  C+ ++D+ L  I +    +  + +  C  +T
Sbjct: 305 LRRCVRLTDEGLRYLVIYCASIKELSVSDCRFVSDFGLREIAKLESRLRYLSIAHCGRVT 364

Query: 234 DQGATLIAQSSKSLRYLGLMRCDKVNEVTVEQLVQ 268
           D G   +A+    LRYL    C+ + +  VE L +
Sbjct: 365 DVGIRYVAKYCSKLRYLNARGCEGITDHGVEYLAK 399



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 18/55 (32%), Positives = 29/55 (52%)

Query: 219 MTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVEQLVQQYPHI 273
           + +ETV V  C+ +TD+G   IAQ    LR L +  C  ++   V  +V   P++
Sbjct: 186 LMLETVTVSGCRRLTDRGLYTIAQCCPELRRLEVSGCYNISNEAVFDVVSLCPNL 240


>gi|16306582 F-box and leucine-rich repeat protein 2 [Homo sapiens]
          Length = 423

 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 68/264 (25%), Positives = 116/264 (43%), Gaps = 26/264 (9%)

Query: 12  KCPGLLRYTAYR-CKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKD 70
           +C G LR  + R C  + D+S+   A +C  ++ +++    K+TD     L   C +LK 
Sbjct: 75  RCGGFLRKLSLRGCIGVGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKH 134

Query: 71  IHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSV 130
           +    C  I++  +  I++GC  L+ + +     +T   ++A    C             
Sbjct: 135 LDLTSCVSITNSSLKGISEGCRNLEYLNLSWCDQITKDGIEALVRGC------------- 181

Query: 131 TSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIA 190
                      R L +L LR  T+L++E +  I   C  L SLNL     I D  V  I 
Sbjct: 182 -----------RGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEGVVQIC 230

Query: 191 KEGQNLKELYLVSC-KITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRY 249
           +    L+ L L  C  +TD +L A+G     ++ ++   C  +TD G TL+A++   L  
Sbjct: 231 RGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNCHELEK 290

Query: 250 LGLMRCDKVNEVTVEQLVQQYPHI 273
           + L  C  + + T+ QL    P +
Sbjct: 291 MDLEECILITDSTLIQLSIHCPKL 314



 Score = 90.9 bits (224), Expect = 1e-18
 Identities = 60/272 (22%), Positives = 130/272 (47%), Gaps = 6/272 (2%)

Query: 1   MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60
           + D+ +   A  C  +       C +++D++  +++  C  L+ + + +   +T+  LK 
Sbjct: 91  VGDSSLKTFAQNCRNIEHLNLNGCTKITDSTCYSLSRFCSKLKHLDLTSCVSITNSSLKG 150

Query: 61  LGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPEL 120
           +   CR L+ ++   C +I+ +G+  + +GC  L+ + ++    + D+++K    +C EL
Sbjct: 151 ISEGCRNLEYLNLSWCDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHEL 210

Query: 121 QYVGFMGCS-VTSKGVIHLTK-LRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLN 178
             +    CS +T +GV+ + +    L +L L   + L + ++  +   C  L  L     
Sbjct: 211 VSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARC 270

Query: 179 WIINDRCVEVIAKEGQNLKELYLVSC-KITDYALIAIGRYSMTIETVDVGWCKEITDQGA 237
             + D    ++A+    L+++ L  C  ITD  LI +  +   ++ + +  C+ ITD G 
Sbjct: 271 SHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGI 330

Query: 238 TLIAQSS---KSLRYLGLMRCDKVNEVTVEQL 266
             ++ S+   + LR L L  C  + +V +E L
Sbjct: 331 LHLSNSTCGHERLRVLELDNCLLITDVALEHL 362



 Score = 83.6 bits (205), Expect = 2e-16
 Identities = 44/169 (26%), Positives = 85/169 (50%), Gaps = 8/169 (4%)

Query: 13  CPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIH 72
           C  L+      C +++D  ++ +   C  LQ + +     LTD  L  LG  C  L+ + 
Sbjct: 207 CHELVSLNLQSCSRITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILE 266

Query: 73  FGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCS-VT 131
             +C  ++D G  ++A+ C +L+++ ++E  L+TD ++   + HCP+LQ +    C  +T
Sbjct: 267 AARCSHLTDAGFTLLARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELIT 326

Query: 132 SKGVIHLTKLRNLSSLDLRHITELDN-----ETVMEIVKRCKNLSSLNL 175
             G++HL+   +    +   + ELDN     +  +E ++ C+ L  L L
Sbjct: 327 DDGILHLS--NSTCGHERLRVLELDNCLLITDVALEHLENCRGLERLEL 373



 Score = 82.0 bits (201), Expect = 6e-16
 Identities = 60/219 (27%), Positives = 109/219 (49%), Gaps = 7/219 (3%)

Query: 24  CKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEG 83
           C Q++   I A+   C  L+ + +    +L DE LK + + C EL  ++   C +I+DEG
Sbjct: 166 CDQITKDGIEALVRGCRGLKALLLRGCTQLEDEALKHIQNYCHELVSLNLQSCSRITDEG 225

Query: 84  MIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCS-VTSKGVIHLTK-L 141
           ++ I +GC +LQ + +     +TD S+ A   +CP LQ +    CS +T  G   L +  
Sbjct: 226 VVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTLLARNC 285

Query: 142 RNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKE---GQNLKE 198
             L  +DL     + + T++++   C  L +L+L    +I D  +  ++      + L+ 
Sbjct: 286 HELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGHERLRV 345

Query: 199 LYLVSC-KITDYALIAIGRYSMTIETVDVGWCKEITDQG 236
           L L +C  ITD AL  +      +E +++  C+++T  G
Sbjct: 346 LELDNCLLITDVALEHL-ENCRGLERLELYDCQQVTRAG 383



 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 42/153 (27%), Positives = 68/153 (44%), Gaps = 4/153 (2%)

Query: 1   MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60
           ++D GV  +   C  L       C  L+D S+ A+  +CP LQ +       LTD G   
Sbjct: 221 ITDEGVVQICRGCHRLQALCLSGCSNLTDASLTALGLNCPRLQILEAARCSHLTDAGFTL 280

Query: 61  LGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHC--- 117
           L   C EL+ +   +C  I+D  +I ++  C KLQ + +   +L+TD  +   +      
Sbjct: 281 LARNCHELEKMDLEECILITDSTLIQLSIHCPKLQALSLSHCELITDDGILHLSNSTCGH 340

Query: 118 PELQYVGFMGC-SVTSKGVIHLTKLRNLSSLDL 149
             L+ +    C  +T   + HL   R L  L+L
Sbjct: 341 ERLRVLELDNCLLITDVALEHLENCRGLERLEL 373


>gi|27734755 F-box and leucine-rich repeat protein 20 [Homo sapiens]
          Length = 436

 Score = 90.1 bits (222), Expect = 2e-18
 Identities = 61/229 (26%), Positives = 111/229 (48%), Gaps = 5/229 (2%)

Query: 13  CPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIH 72
           CP L +     C Q++   I A+   C  L+ + +    +L DE LK +G+ C EL  ++
Sbjct: 168 CPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLN 227

Query: 73  FGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCS-VT 131
              C +I+DEG+I I +GC KLQ +       +TD  + A  ++CP L+ +    CS +T
Sbjct: 228 LQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLT 287

Query: 132 SKGVIHLTK-LRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVI- 189
             G   L +    L  +DL    ++ + T++++   C  L  L+L    +I D  +  + 
Sbjct: 288 DVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLG 347

Query: 190 --AKEGQNLKELYLVSCKITDYALIAIGRYSMTIETVDVGWCKEITDQG 236
             A     L+ + L +C +   A +   +   ++E +++  C++IT  G
Sbjct: 348 NGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAG 396



 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 61/290 (21%), Positives = 132/290 (45%), Gaps = 8/290 (2%)

Query: 1   MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60
           + DN +   A  C  +       C + +D +  +++  C  L+ + + +   +T+  LK 
Sbjct: 104 VGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKA 163

Query: 61  LGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPEL 120
           L   C  L+ ++   C +++ +G+  + +GC  L+ ++++    + D+++K    HCPEL
Sbjct: 164 LSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPEL 223

Query: 121 QYVGFMGC-SVTSKGVIHLTK-LRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLN 178
             +    C  +T +G+I + +    L SL     + + +  +  + + C  L  L +   
Sbjct: 224 VTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARC 283

Query: 179 WIINDRCVEVIAKEGQNLKELYLVSC-KITDYALIAIGRYSMTIETVDVGWCKEITDQGA 237
             + D     +A+    L+++ L  C +ITD  LI +  +   ++ + +  C+ ITD G 
Sbjct: 284 SQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGI 343

Query: 238 TLI---AQSSKSLRYLGLMRCDKVNEVTVEQLVQQYPHITFSTVLQDCKR 284
             +   A +   L  + L  C  + + ++E L  +  H      L DC++
Sbjct: 344 RHLGNGACAHDQLEVIELDNCPLITDASLEHL--KSCHSLERIELYDCQQ 391



 Score = 85.5 bits (210), Expect = 5e-17
 Identities = 62/264 (23%), Positives = 114/264 (43%), Gaps = 26/264 (9%)

Query: 12  KCPGLLRYTAYR-CKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKD 70
           +C G LR  + R C  + D ++   A +C  ++ +++    K TD     L   C +L+ 
Sbjct: 88  RCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRH 147

Query: 71  IHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSV 130
           +    C  I++  +  +++GC  L+++ +     VT   ++A    C  L+ +   GC  
Sbjct: 148 LDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGC-- 205

Query: 131 TSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIA 190
                                 T+L++E +  I   C  L +LNL     I D  +  I 
Sbjct: 206 ----------------------TQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITIC 243

Query: 191 KEGQNLKELYLVSC-KITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRY 249
           +    L+ L    C  ITD  L A+G+    +  ++V  C ++TD G T +A++   L  
Sbjct: 244 RGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEK 303

Query: 250 LGLMRCDKVNEVTVEQLVQQYPHI 273
           + L  C ++ + T+ QL    P +
Sbjct: 304 MDLEECVQITDSTLIQLSIHCPRL 327



 Score = 62.0 bits (149), Expect = 6e-10
 Identities = 34/124 (27%), Positives = 66/124 (53%), Gaps = 4/124 (3%)

Query: 1   MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60
           ++D G   LA  C  L +     C Q++D+++I ++ HCP LQ + + + + +TD+G++ 
Sbjct: 286 LTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRH 345

Query: 61  LGSKC---RELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHC 117
           LG+      +L+ I    C  I+D  +  + K C  L+RI + + + +T   +K    H 
Sbjct: 346 LGNGACAHDQLEVIELDNCPLITDASLEHL-KSCHSLERIELYDCQQITRAGIKRLRTHL 404

Query: 118 PELQ 121
           P ++
Sbjct: 405 PNIK 408


>gi|161333852 F-box and leucine-rich repeat protein 13 isoform 1
           [Homo sapiens]
          Length = 735

 Score = 82.0 bits (201), Expect = 6e-16
 Identities = 80/316 (25%), Positives = 134/316 (42%), Gaps = 57/316 (18%)

Query: 13  CPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIH 72
           C  L+      C Q+S      +A+ C  +  + + +   LTD  +K L  KC  +  + 
Sbjct: 323 CHKLIYLDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLV 382

Query: 73  FGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCS-VT 131
           F     ISD      A    KL++I  + NK VTD S K   ++ P L ++    C  +T
Sbjct: 383 FTGAPHISD--CTFRALSACKLRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGIT 440

Query: 132 SKGVIHLTKLRNLS----------------------------SLDLRHITELDNETVMEI 163
              +  L+ L+ L+                             L+L +   L + +VM++
Sbjct: 441 DSSLRSLSPLKQLTVLNLANCVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKL 500

Query: 164 VKRCKNLSSLNL--C-------LNWIIN-------DRCVEVIAKEGQN-------LKELY 200
            +RC NL+ L+L  C       + +I+N       D     I+ EG N       LKEL 
Sbjct: 501 SERCPNLNYLSLRNCEHLTAQGIGYIVNIFSLVSIDLSGTDISNEGLNVLSRHKKLKELS 560

Query: 201 LVSC-KITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVN 259
           +  C +ITD  + A  + S+ +E +DV +C +++D     +A    +L  L +  C K+ 
Sbjct: 561 VSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPKIT 620

Query: 260 EVTVEQLVQQ--YPHI 273
           +  +E L  +  Y HI
Sbjct: 621 DSAMEMLSAKCHYLHI 636



 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 64/283 (22%), Positives = 126/283 (44%), Gaps = 36/283 (12%)

Query: 25  KQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGM 84
           K+++D S   +  + P L  +++ +   +TD  L+ L S  ++L  ++   C +I D G+
Sbjct: 411 KRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSL-SPLKQLTVLNLANCVRIGDMGL 469

Query: 85  IVIAKG--CLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCS-VTSKGVIHLTKL 141
                G   ++++ + +     ++D SV   +E CP L Y+    C  +T++G+ ++  +
Sbjct: 470 KQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNI 529

Query: 142 RNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQ------- 194
            +L S+DL   T++ NE  + ++ R K L  L++   + I D  ++   K          
Sbjct: 530 FSLVSIDLSG-TDISNEG-LNVLSRHKKLKELSVSECYRITDDGIQAFCKSSLILEHLDV 587

Query: 195 -------------------NLKELYLVSC-KITDYALIAIGRYSMTIETVDVGWCKEITD 234
                              NL  L +  C KITD A+  +      +  +D+  C  +TD
Sbjct: 588 SYCSQLSDMIIKALAIYCINLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISGCVLLTD 647

Query: 235 QGATLIAQSSKSLRYLGLMRCDKVNEVTVEQL---VQQYPHIT 274
           Q    +    K LR L +  C  +++   +++   VQQ  + T
Sbjct: 648 QILEDLQIGCKQLRILKMQYCTNISKKAAQRMSSKVQQQEYNT 690



 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 72/281 (25%), Positives = 122/281 (43%), Gaps = 44/281 (15%)

Query: 13  CPGLLRYTAYRCKQLSDTSII-----AVASHCPLLQKVHVGNQDKLTDEGLK--QLGSKC 65
           CPG+L      C  LS+T+I       +  H   LQ + +    + TD+GL+   LG+ C
Sbjct: 270 CPGVL------CLNLSNTTITNRTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGC 323

Query: 66  RELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGF 125
            +L  +    C +IS +G   IA  C  +  + + +   +TD  VKA  E C  +  + F
Sbjct: 324 HKLIYLDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLVF 383

Query: 126 MGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRC 185
            G    S         R LS+  LR I    N+ V                      D  
Sbjct: 384 TGAPHISD-----CTFRALSACKLRKIRFEGNKRV---------------------TDAS 417

Query: 186 VEVIAKEGQNLKELYLVSCK-ITDYALIAIGRYSMTIETVDVGWCKEITDQGAT--LIAQ 242
            + I K   NL  +Y+  CK ITD +L ++      +  +++  C  I D G    L   
Sbjct: 418 FKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQ-LTVLNLANCVRIGDMGLKQFLDGP 476

Query: 243 SSKSLRYLGLMRCDKVNEVTVEQLVQQYPHITFSTVLQDCK 283
           +S  +R L L  C ++++ +V +L ++ P++ + + L++C+
Sbjct: 477 ASMRIRELNLSNCVRLSDASVMKLSERCPNLNYLS-LRNCE 516



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 40/155 (25%), Positives = 73/155 (47%), Gaps = 4/155 (2%)

Query: 123 VGFMGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIIN 182
           + F GC +  K    ++  RNL  L++       +E++  I + C  +  LNL  N  I 
Sbjct: 226 LNFRGCLLRPKTFRSVSHCRNLQELNVSDCPTFTDESMRHISEGCPGVLCLNLS-NTTIT 284

Query: 183 DRCVEVIAKEGQNLKELYLVSC-KITDYAL--IAIGRYSMTIETVDVGWCKEITDQGATL 239
           +R + ++ +   NL+ L L  C + TD  L  + +G     +  +D+  C +I+ QG   
Sbjct: 285 NRTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRY 344

Query: 240 IAQSSKSLRYLGLMRCDKVNEVTVEQLVQQYPHIT 274
           IA S   + +L +     + +  V+ LV++   IT
Sbjct: 345 IANSCTGIMHLTINDMPTLTDNCVKALVEKCSRIT 379



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 25/99 (25%), Positives = 50/99 (50%)

Query: 24  CKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEG 83
           C QLSD  I A+A +C  L  + +    K+TD  ++ L +KC  L  +    C  ++D+ 
Sbjct: 590 CSQLSDMIIKALAIYCINLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISGCVLLTDQI 649

Query: 84  MIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQY 122
           +  +  GC +L+ + MQ    ++ ++ +  +    + +Y
Sbjct: 650 LEDLQIGCKQLRILKMQYCTNISKKAAQRMSSKVQQQEY 688



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 33/133 (24%), Positives = 62/133 (46%), Gaps = 1/133 (0%)

Query: 1   MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60
           +S+ G+ VL+ +   L   +   C +++D  I A      +L+ + V    +L+D  +K 
Sbjct: 542 ISNEGLNVLS-RHKKLKELSVSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKA 600

Query: 61  LGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPEL 120
           L   C  L  +    C KI+D  M +++  C  L  + +    L+TDQ ++     C +L
Sbjct: 601 LAIYCINLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQL 660

Query: 121 QYVGFMGCSVTSK 133
           + +    C+  SK
Sbjct: 661 RILKMQYCTNISK 673



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 33/188 (17%), Positives = 76/188 (40%), Gaps = 25/188 (13%)

Query: 1   MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSI-----------------------IAVAS 37
           +SD  V  L+ +CP L   +   C+ L+   I                       + V S
Sbjct: 492 LSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFSLVSIDLSGTDISNEGLNVLS 551

Query: 38  HCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRI 97
               L+++ V    ++TD+G++        L+ +    C ++SD  +  +A  C+ L  +
Sbjct: 552 RHKKLKELSVSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKALAIYCINLTSL 611

Query: 98  YMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKL--RNLSSLDLRHITEL 155
            +     +TD +++  +  C  L  +   GC + +  ++   ++  + L  L +++ T +
Sbjct: 612 SIAGCPKITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLRILKMQYCTNI 671

Query: 156 DNETVMEI 163
             +    +
Sbjct: 672 SKKAAQRM 679


>gi|161333854 F-box and leucine-rich repeat protein 13 isoform 2
           [Homo sapiens]
          Length = 690

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 72/281 (25%), Positives = 122/281 (43%), Gaps = 44/281 (15%)

Query: 13  CPGLLRYTAYRCKQLSDTSII-----AVASHCPLLQKVHVGNQDKLTDEGLK--QLGSKC 65
           CPG+L      C  LS+T+I       +  H   LQ + +    + TD+GL+   LG+ C
Sbjct: 270 CPGVL------CLNLSNTTITNRTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGC 323

Query: 66  RELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGF 125
            +L  +    C +IS +G   IA  C  +  + + +   +TD  VKA  E C  +  + F
Sbjct: 324 HKLIYLDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLVF 383

Query: 126 MGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRC 185
            G    S         R LS+  LR I    N+ V                      D  
Sbjct: 384 TGAPHISD-----CTFRALSACKLRKIRFEGNKRV---------------------TDAS 417

Query: 186 VEVIAKEGQNLKELYLVSCK-ITDYALIAIGRYSMTIETVDVGWCKEITDQGAT--LIAQ 242
            + I K   NL  +Y+  CK ITD +L ++      +  +++  C  I D G    L   
Sbjct: 418 FKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQ-LTVLNLANCVRIGDMGLKQFLDGP 476

Query: 243 SSKSLRYLGLMRCDKVNEVTVEQLVQQYPHITFSTVLQDCK 283
           +S  +R L L  C ++++ +V +L ++ P++ + + L++C+
Sbjct: 477 ASMRIRELNLSNCVRLSDASVMKLSERCPNLNYLS-LRNCE 516



 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 58/256 (22%), Positives = 119/256 (46%), Gaps = 27/256 (10%)

Query: 25  KQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGM 84
           K+++D S   +  + P L  +++ +   +TD  L+ L S  ++L  ++   C +I D G+
Sbjct: 411 KRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSL-SPLKQLTVLNLANCVRIGDMGL 469

Query: 85  IVIAKG--CLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCS-VTSKGVIHLTKL 141
                G   ++++ + +     ++D SV   +E CP L Y+    C  +T++G+ ++  +
Sbjct: 470 KQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNI 529

Query: 142 RNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYL 201
            +L S+DL   T++ NE  + ++ R K L  L++   + I D  ++              
Sbjct: 530 FSLVSIDLSG-TDISNEG-LNVLSRHKKLKELSVSECYRITDDGIQ-------------- 573

Query: 202 VSCKITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNEV 261
               ITD A+  +      +  +D+  C  +TDQ    +    K LR L +  C  +++ 
Sbjct: 574 ----ITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLRILKMQYCTNISKK 629

Query: 262 TVEQL---VQQYPHIT 274
             +++   VQQ  + T
Sbjct: 630 AAQRMSSKVQQQEYNT 645



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 40/155 (25%), Positives = 73/155 (47%), Gaps = 4/155 (2%)

Query: 123 VGFMGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIIN 182
           + F GC +  K    ++  RNL  L++       +E++  I + C  +  LNL  N  I 
Sbjct: 226 LNFRGCLLRPKTFRSVSHCRNLQELNVSDCPTFTDESMRHISEGCPGVLCLNLS-NTTIT 284

Query: 183 DRCVEVIAKEGQNLKELYLVSC-KITDYAL--IAIGRYSMTIETVDVGWCKEITDQGATL 239
           +R + ++ +   NL+ L L  C + TD  L  + +G     +  +D+  C +I+ QG   
Sbjct: 285 NRTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRY 344

Query: 240 IAQSSKSLRYLGLMRCDKVNEVTVEQLVQQYPHIT 274
           IA S   + +L +     + +  V+ LV++   IT
Sbjct: 345 IANSCTGIMHLTINDMPTLTDNCVKALVEKCSRIT 379



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 35/141 (24%), Positives = 65/141 (46%), Gaps = 32/141 (22%)

Query: 24  CKQLSDTSIIAVASHCPLLQKVHVGNQDKLT------------------------DEGLK 59
           C +LSD S++ ++  CP L  + + N + LT                        +EGL 
Sbjct: 489 CVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFSLVSIDLSGTDISNEGLN 548

Query: 60  QLGSKCRELKDIHFGQCYKISDEG-------MIVIAKGCLKLQRIYMQENKLVTDQSVKA 112
            L S+ ++LK++   +CY+I+D+G       M +++  C  L  + +    L+TDQ ++ 
Sbjct: 549 VL-SRHKKLKELSVSECYRITDDGIQITDSAMEMLSAKCHYLHILDISGCVLLTDQILED 607

Query: 113 FAEHCPELQYVGFMGCSVTSK 133
               C +L+ +    C+  SK
Sbjct: 608 LQIGCKQLRILKMQYCTNISK 628



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 29/152 (19%), Positives = 62/152 (40%), Gaps = 30/152 (19%)

Query: 1   MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSI-----------------------IAVAS 37
           +SD  V  L+ +CP L   +   C+ L+   I                       + V S
Sbjct: 492 LSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFSLVSIDLSGTDISNEGLNVLS 551

Query: 38  HCPLLQKVHVGNQDKLTDEGLK-------QLGSKCRELKDIHFGQCYKISDEGMIVIAKG 90
               L+++ V    ++TD+G++        L +KC  L  +    C  ++D+ +  +  G
Sbjct: 552 RHKKLKELSVSECYRITDDGIQITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIG 611

Query: 91  CLKLQRIYMQENKLVTDQSVKAFAEHCPELQY 122
           C +L+ + MQ    ++ ++ +  +    + +Y
Sbjct: 612 CKQLRILKMQYCTNISKKAAQRMSSKVQQQEY 643


>gi|164663798 antagonist of mitotic exit network 1 homolog [Homo
           sapiens]
          Length = 258

 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 49/174 (28%), Positives = 86/174 (49%), Gaps = 8/174 (4%)

Query: 23  RCKQLSDTSIIAVASHCPLLQKVHV----GNQDKLTDEGLKQLGSKCRELKDIHFGQCYK 78
           R   +SD +++ + S+C  L+K+++    GN+  +T EG+K + S C  L +    +C  
Sbjct: 69  RSCDISDAALLHL-SNCRKLKKLNLNASKGNRVSVTSEGIKAVASSCSYLHEASLKRCCN 127

Query: 79  ISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHL 138
           ++DEG++ +A  C  L+ I +     +TD S+ A  ++CP LQ V F    V+  GVI L
Sbjct: 128 LTDEGVVALALNCQLLKIIDLGGCLSITDVSLHALGKNCPFLQCVDFSATQVSDSGVIAL 187

Query: 139 TK---LRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVI 189
                 + L  + + H   L +  V  ++  C  +  L      +I D   EV+
Sbjct: 188 VSGPCAKKLEEIHMGHCVNLTDGAVEAVLTYCPQIRILLFHGCPLITDHSREVL 241



 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 40/130 (30%), Positives = 70/130 (53%), Gaps = 3/130 (2%)

Query: 1   MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60
           ++  G+  +A  C  L   +  RC  L+D  ++A+A +C LL+ + +G    +TD  L  
Sbjct: 102 VTSEGIKAVASSCSYLHEASLKRCCNLTDEGVVALALNCQLLKIIDLGGCLSITDVSLHA 161

Query: 61  LGSKCRELKDIHFGQCYKISDEGMIVIAKG--CLKLQRIYMQENKLVTDQSVKAFAEHCP 118
           LG  C  L+ + F    ++SD G+I +  G    KL+ I+M     +TD +V+A   +CP
Sbjct: 162 LGKNCPFLQCVDF-SATQVSDSGVIALVSGPCAKKLEEIHMGHCVNLTDGAVEAVLTYCP 220

Query: 119 ELQYVGFMGC 128
           +++ + F GC
Sbjct: 221 QIRILLFHGC 230



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 46/198 (23%), Positives = 79/198 (39%), Gaps = 38/198 (19%)

Query: 105 VTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLR----HITELDNETV 160
           +TD ++       PE+Q +    C ++   ++HL+  R L  L+L     +   + +E +
Sbjct: 50  ITDSNISEILH--PEVQTLDLRSCDISDAALLHLSNCRKLKKLNLNASKGNRVSVTSEGI 107

Query: 161 MEIVKRCKNL--SSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSC-KITDYALIAIGR- 216
             +   C  L  +SL  C N  + D  V  +A   Q LK + L  C  ITD +L A+G+ 
Sbjct: 108 KAVASSCSYLHEASLKRCCN--LTDEGVVALALNCQLLKIIDLGGCLSITDVSLHALGKN 165

Query: 217 --------YSMT------------------IETVDVGWCKEITDQGATLIAQSSKSLRYL 250
                   +S T                  +E + +G C  +TD     +      +R L
Sbjct: 166 CPFLQCVDFSATQVSDSGVIALVSGPCAKKLEEIHMGHCVNLTDGAVEAVLTYCPQIRIL 225

Query: 251 GLMRCDKVNEVTVEQLVQ 268
               C  + + + E L Q
Sbjct: 226 LFHGCPLITDHSREVLEQ 243


>gi|190194416 F-box and leucine-rich repeat protein 15 [Homo
           sapiens]
          Length = 300

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 47/169 (27%), Positives = 84/169 (49%), Gaps = 3/169 (1%)

Query: 1   MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60
           +SD  +  +  + P L       C QLS  ++ A+A  CP LQ++ + + D +    L+ 
Sbjct: 101 LSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRG 160

Query: 61  LGSKCRELKDIHFGQCYKISDEGMIVIA-KGCLKLQRIYMQENKLVTDQSVKAFAEHCPE 119
           L  +C  L+++    C ++ DE ++ +A +    L+ + +  N  V D +V+  A +CPE
Sbjct: 161 LADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPE 220

Query: 120 LQYVGFMGC-SVTSKGVIHLTK-LRNLSSLDLRHITELDNETVMEIVKR 166
           L ++   GC  V S GV  L +    L SL +RH   +   ++  + KR
Sbjct: 221 LHHLDLTGCLRVGSDGVRTLAEYCPVLRSLRVRHCHHVAESSLSRLRKR 269



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 43/202 (21%), Positives = 84/202 (41%), Gaps = 27/202 (13%)

Query: 68  LKDIHFGQCYK-ISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFM 126
           L+++    C++ +SDE ++ +     +L+ + +     ++ +++ A AE CP LQ     
Sbjct: 89  LQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPRLQ----- 143

Query: 127 GCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCV 186
                               L L H   +D   +  +  RC  L  L+L     + D  +
Sbjct: 144 -------------------RLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAI 184

Query: 187 EVIA-KEGQNLKELYL-VSCKITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSS 244
             +A + G  L+ L L V+  + D A+  + R    +  +D+  C  +   G   +A+  
Sbjct: 185 VYLAQRRGAGLRSLSLAVNANVGDAAVQELARNCPELHHLDLTGCLRVGSDGVRTLAEYC 244

Query: 245 KSLRYLGLMRCDKVNEVTVEQL 266
             LR L +  C  V E ++ +L
Sbjct: 245 PVLRSLRVRHCHHVAESSLSRL 266



 Score = 35.0 bits (79), Expect = 0.082
 Identities = 19/85 (22%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 189 IAKEGQNLKELYLVSCK--ITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKS 246
           + ++ + L+EL L  C   ++D  L+ +   +  + +V +G C +++ +    +A+    
Sbjct: 82  LLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALGGCGQLSRRALGALAEGCPR 141

Query: 247 LRYLGLMRCDKVNEVTVEQLVQQYP 271
           L+ L L  CD V+ + +  L  + P
Sbjct: 142 LQRLSLAHCDWVDGLALRGLADRCP 166


>gi|16306588 F-box and leucine-rich repeat protein 4 [Homo sapiens]
          Length = 621

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 42/184 (22%), Positives = 84/184 (45%), Gaps = 33/184 (17%)

Query: 12  KCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGL--KQLGSKCRELK 69
           K   L R   YR K +  T+++++ + C  LQ + +G+   + D  +    +G+KC++L+
Sbjct: 424 KLCSLKRLVLYRTK-VEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLR 482

Query: 70  DIHFGQCYKISDEGMIVIAKGCL----------------------------KLQRIYMQE 101
            +   +C  I++ G+  +A GC                              LQ++++  
Sbjct: 483 TLDLWRCKNITENGIAELASGCPLLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTA 542

Query: 102 NKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIH--LTKLRNLSSLDLRHITELDNET 159
           N+ V D  +   A +C  LQ +  +G  + S   +   L   ++LS LD+   +++DN  
Sbjct: 543 NRSVCDTDIDELACNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDNRA 602

Query: 160 VMEI 163
           V+E+
Sbjct: 603 VLEL 606



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 68/266 (25%), Positives = 117/266 (43%), Gaps = 22/266 (8%)

Query: 14  PGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQD---KLTDEGLKQLGSKCRELKD 70
           P L R  A  CK LS          C  LQ +H+  Q    KL D  L+ L S+C  ++ 
Sbjct: 298 PDLCRL-AQTCKLLSQHC-------CDPLQYIHLNLQPYWAKLDDTSLEFLQSRCTLVQW 349

Query: 71  IHF---GQCYKISDEGMIVIAKGC-LKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFM 126
           ++    G    IS  G     K C  +L R+ +  +  + +  ++  +E CP LQ +   
Sbjct: 350 LNLSWTGNRGFISVAGFSRFLKVCGSELVRLELSCSHFLNETCLEVISEMCPNLQALNLS 409

Query: 127 GC-SVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNL--CLNWIIND 183
            C  +  +   H+ KL +L  L L + T+++   ++ I+  C  L  L+L  C+     D
Sbjct: 410 SCDKLPPQAFNHIAKLCSLKRLVL-YRTKVEQTALLSILNFCSELQHLSLGSCVMIEDYD 468

Query: 184 RCVEVIAKEGQNLKELYLVSCK-ITDYALIAIGRYSMTIETVDVGWCKEITDQGA--TLI 240
               +I  + + L+ L L  CK IT+  +  +      +E +D+GWC  +       T +
Sbjct: 469 VIASMIGAKCKKLRTLDLWRCKNITENGIAELASGCPLLEELDLGWCPTLQSSTGCFTRL 528

Query: 241 AQSSKSLRYLGLMRCDKVNEVTVEQL 266
           A    +L+ L L     V +  +++L
Sbjct: 529 AHQLPNLQKLFLTANRSVCDTDIDEL 554



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 46/250 (18%), Positives = 102/250 (40%), Gaps = 27/250 (10%)

Query: 27  LSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMIV 86
           L++T +  ++  CP LQ +++ + DKL  +    +   C   + + +    K+    ++ 
Sbjct: 388 LNETCLEVISEMCPNLQALNLSSCDKLPPQAFNHIAKLCSLKRLVLYRT--KVEQTALLS 445

Query: 87  IAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSS 146
           I   C +LQ + +    ++ D  V A          +G               K + L +
Sbjct: 446 ILNFCSELQHLSLGSCVMIEDYDVIA--------SMIG--------------AKCKKLRT 483

Query: 147 LDLRHITELDNETVMEIVKRCKNLSSLNL--CLNWIINDRCVEVIAKEGQNLKELYLVSC 204
           LDL     +    + E+   C  L  L+L  C     +  C   +A +  NL++L+L + 
Sbjct: 484 LDLWRCKNITENGIAELASGCPLLEELDLGWCPTLQSSTGCFTRLAHQLPNLQKLFLTAN 543

Query: 205 K-ITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNEVTV 263
           + + D  +  +      ++ +D+   + ++      + +S K L  L +  C +++   V
Sbjct: 544 RSVCDTDIDELACNCTRLQQLDILGTRMVSPASLRKLLESCKDLSLLDVSFCSQIDNRAV 603

Query: 264 EQLVQQYPHI 273
            +L   +P +
Sbjct: 604 LELNASFPKV 613



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 38/160 (23%), Positives = 63/160 (39%), Gaps = 41/160 (25%)

Query: 170 LSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSC------------------------- 204
           L  L L  +  +N+ C+EVI++   NL+ L L SC                         
Sbjct: 377 LVRLELSCSHFLNETCLEVISEMCPNLQALNLSSCDKLPPQAFNHIAKLCSLKRLVLYRT 436

Query: 205 KITDYALIAIGRYSMTIETVDVGWCKEITDQG--ATLIAQSSKSLRYLGLMRCDKVNEVT 262
           K+   AL++I  +   ++ + +G C  I D    A++I    K LR L L RC  + E  
Sbjct: 437 KVEQTALLSILNFCSELQHLSLGSCVMIEDYDVIASMIGAKCKKLRTLDLWRCKNITENG 496

Query: 263 VEQLVQQYPHITFSTVLQDCKRTLERAYQMGWTPNMSAAS 302
           + +L    P              L     +GW P + +++
Sbjct: 497 IAELASGCP--------------LLEELDLGWCPTLQSST 522


>gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]
          Length = 479

 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 53/218 (24%), Positives = 104/218 (47%), Gaps = 6/218 (2%)

Query: 53  LTDEGLKQLGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKA 112
           +TD GL+ +  + + +  +    C   ++ G+        ++  + + +   V D ++ A
Sbjct: 205 ITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSA--RITSLSVSDCINVADDAIAA 262

Query: 113 FAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLRHIT--ELDNETVMEIVKRCKNL 170
            ++  P L  +      VT   + + T  +  S+  LR ++  E+ N  V+ +V    NL
Sbjct: 263 ISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNL 322

Query: 171 SSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSC-KITDYALIAIGRYSMTIETVDVGWC 229
           ++L+L     + D  VE++A+  + L+ L L  C +ITD AL  +      +E + +  C
Sbjct: 323 TALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELVLDRC 382

Query: 230 KEITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVEQLV 267
             ITD G + ++  S SLR L L  C +V +  ++ L+
Sbjct: 383 VRITDTGLSYLSTMS-SLRSLYLRWCCQVQDFGLKHLL 419



 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 37/181 (20%), Positives = 84/181 (46%), Gaps = 2/181 (1%)

Query: 105 VTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIV 164
           +TD  ++   E    +  +   GC+  ++  +  +    ++SL +     + ++ +  I 
Sbjct: 205 ITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAIS 264

Query: 165 KRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSC-KITDYALIAIGRYSMTIET 223
           +   NL+ L+L    + +       A++G +   L L+SC +IT++ ++ +      +  
Sbjct: 265 QLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTA 324

Query: 224 VDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVEQLVQQYPHITFSTVLQDCK 283
           + +  C ++TD G  L+A++ + LR L L  C ++ ++ +E +     H     VL  C 
Sbjct: 325 LSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDL-HRLEELVLDRCV 383

Query: 284 R 284
           R
Sbjct: 384 R 384



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 32/150 (21%), Positives = 72/150 (48%), Gaps = 3/150 (2%)

Query: 1   MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60
           ++++GV  +    P L   +   C +++D  +  VA +   L+ + +    ++TD  L+ 
Sbjct: 307 ITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEY 366

Query: 61  LGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPEL 120
           +      L+++   +C +I+D G+  ++     L+ +Y++    V D  +K        L
Sbjct: 367 VACDLHRLEELVLDRCVRITDTGLSYLST-MSSLRSLYLRWCCQVQDFGLKHLLA-LGSL 424

Query: 121 QYVGFMGCS-VTSKGVIHLTKLRNLSSLDL 149
           + +   GC  +T+ G+  L +L+ L  L+L
Sbjct: 425 RLLSPAGCPLLTTTGLSGLVQLQELEELEL 454



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 25/124 (20%), Positives = 54/124 (43%)

Query: 24  CKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEG 83
           C ++++  ++ V    P L  + +    K+TD+G++ +    R+L+ +    C +I+D  
Sbjct: 304 CWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMA 363

Query: 84  MIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRN 143
           +  +A    +L+ + +     +TD  +   +             C V   G+ HL  L +
Sbjct: 364 LEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCCQVQDFGLKHLLALGS 423

Query: 144 LSSL 147
           L  L
Sbjct: 424 LRLL 427


>gi|51873034 F-box and leucine-rich repeat protein 9 [Homo sapiens]
          Length = 223

 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 23/76 (30%), Positives = 39/76 (51%)

Query: 1   MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60
           ++DNG+  +A  CP L       C +LSD      AS  P LQ +++ +  +L ++ L  
Sbjct: 113 LTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDA 172

Query: 61  LGSKCRELKDIHFGQC 76
           +G  CR+L+ +    C
Sbjct: 173 IGQACRQLRVLDVATC 188



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 26/105 (24%), Positives = 49/105 (46%), Gaps = 1/105 (0%)

Query: 24  CKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEG 83
           C +L+D S+  V     L Q + +    +LTD GL  +   C  L+ +    C ++SD+G
Sbjct: 85  CSKLTDASLAKVLQFLQLRQ-LSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSDKG 143

Query: 84  MIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGC 128
               A    +LQ + +     + +Q++ A  + C +L+ +    C
Sbjct: 144 WAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATC 188



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 22/98 (22%), Positives = 51/98 (52%)

Query: 26  QLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMI 85
           +L+D  ++AVA  CP L+ + + +  +L+D+G  Q  S    L+ ++   C ++ ++ + 
Sbjct: 112 ELTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLD 171

Query: 86  VIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYV 123
            I + C +L+ + +     +   +V+ F    P++  V
Sbjct: 172 AIGQACRQLRVLDVATCPGINMAAVRRFQAQLPQVSCV 209



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 26/96 (27%), Positives = 51/96 (53%), Gaps = 5/96 (5%)

Query: 196 LKELYLVSC-KITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMR 254
           L+EL L +C K+TD +L  + ++ + +  + +    E+TD G   +A+   SL +L L  
Sbjct: 77  LQELDLTACSKLTDASLAKVLQF-LQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135

Query: 255 CDKVNEVTVEQLVQQYP---HITFSTVLQDCKRTLE 287
           C ++++    Q    +P   H+  S+  Q  ++TL+
Sbjct: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLD 171



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 21/88 (23%), Positives = 45/88 (51%), Gaps = 1/88 (1%)

Query: 42  LQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQE 101
           LQ++ +    KLTD  L ++  +  +L+ +      +++D G++ +A+GC  L+ + +  
Sbjct: 77  LQELDLTACSKLTDASLAKV-LQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135

Query: 102 NKLVTDQSVKAFAEHCPELQYVGFMGCS 129
              ++D+     A   P LQ++    CS
Sbjct: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCS 163



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 18/64 (28%), Positives = 36/64 (56%)

Query: 205 KITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVE 264
           ++TD  L+A+ R   ++E + +  C  ++D+G    A S   L++L L  C ++ E T++
Sbjct: 112 ELTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLD 171

Query: 265 QLVQ 268
            + Q
Sbjct: 172 AIGQ 175


>gi|16306591 F-box and leucine-rich repeat protein 9 [Homo sapiens]
          Length = 223

 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 23/76 (30%), Positives = 39/76 (51%)

Query: 1   MSDNGVCVLAFKCPGLLRYTAYRCKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQ 60
           ++DNG+  +A  CP L       C +LSD      AS  P LQ +++ +  +L ++ L  
Sbjct: 113 LTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLDA 172

Query: 61  LGSKCRELKDIHFGQC 76
           +G  CR+L+ +    C
Sbjct: 173 IGQACRQLRVLDVATC 188



 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 26/105 (24%), Positives = 49/105 (46%), Gaps = 1/105 (0%)

Query: 24  CKQLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEG 83
           C +L+D S+  V     L Q + +    +LTD GL  +   C  L+ +    C ++SD+G
Sbjct: 85  CSKLTDASLAKVLQFLQLRQ-LSLSLLPELTDNGLVAVARGCPSLEHLALSHCSRLSDKG 143

Query: 84  MIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGC 128
               A    +LQ + +     + +Q++ A  + C +L+ +    C
Sbjct: 144 WAQAASSWPRLQHLNLSSCSQLIEQTLDAIGQACRQLRVLDVATC 188



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 22/98 (22%), Positives = 51/98 (52%)

Query: 26  QLSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMI 85
           +L+D  ++AVA  CP L+ + + +  +L+D+G  Q  S    L+ ++   C ++ ++ + 
Sbjct: 112 ELTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLD 171

Query: 86  VIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYV 123
            I + C +L+ + +     +   +V+ F    P++  V
Sbjct: 172 AIGQACRQLRVLDVATCPGINMAAVRRFQAQLPQVSCV 209



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 26/96 (27%), Positives = 51/96 (53%), Gaps = 5/96 (5%)

Query: 196 LKELYLVSC-KITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMR 254
           L+EL L +C K+TD +L  + ++ + +  + +    E+TD G   +A+   SL +L L  
Sbjct: 77  LQELDLTACSKLTDASLAKVLQF-LQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135

Query: 255 CDKVNEVTVEQLVQQYP---HITFSTVLQDCKRTLE 287
           C ++++    Q    +P   H+  S+  Q  ++TL+
Sbjct: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLD 171



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 21/88 (23%), Positives = 45/88 (51%), Gaps = 1/88 (1%)

Query: 42  LQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQE 101
           LQ++ +    KLTD  L ++  +  +L+ +      +++D G++ +A+GC  L+ + +  
Sbjct: 77  LQELDLTACSKLTDASLAKV-LQFLQLRQLSLSLLPELTDNGLVAVARGCPSLEHLALSH 135

Query: 102 NKLVTDQSVKAFAEHCPELQYVGFMGCS 129
              ++D+     A   P LQ++    CS
Sbjct: 136 CSRLSDKGWAQAASSWPRLQHLNLSSCS 163



 Score = 37.7 bits (86), Expect = 0.013
 Identities = 18/64 (28%), Positives = 36/64 (56%)

Query: 205 KITDYALIAIGRYSMTIETVDVGWCKEITDQGATLIAQSSKSLRYLGLMRCDKVNEVTVE 264
           ++TD  L+A+ R   ++E + +  C  ++D+G    A S   L++L L  C ++ E T++
Sbjct: 112 ELTDNGLVAVARGCPSLEHLALSHCSRLSDKGWAQAASSWPRLQHLNLSSCSQLIEQTLD 171

Query: 265 QLVQ 268
            + Q
Sbjct: 172 AIGQ 175


>gi|16306580 F-box and leucine-rich repeat protein 11 [Homo sapiens]
          Length = 1162

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 38/176 (21%), Positives = 76/176 (43%), Gaps = 20/176 (11%)

Query: 118  PELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCL 177
            P L+ +   GCS ++   +  +    L +LDLR    + +  + +++             
Sbjct: 977  PGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPA--------- 1027

Query: 178  NWIINDRCVEVIAKEGQNLKELYLVSCKITDYALIAIGRYSMTIETVDVGWCKEITDQGA 237
                 D+  +    + +N+ +  L    ITD  L  I R+   +  +D+  C  +TDQ +
Sbjct: 1028 -----DKPGQDNRSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQSS 1082

Query: 238  TLIAQSSKSLRY----LGLMRCDKVNEVTVEQLVQQYPHITFSTVLQDCKRTLERA 289
             L+     S RY    L +  C+K+ + T+  L ++  ++T    L+ CK+   +A
Sbjct: 1083 NLLTAVGSSTRYSLTELNMAGCNKLTDQTLIYL-RRIANVTLID-LRGCKQITRKA 1136



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 17/67 (25%), Positives = 37/67 (55%), Gaps = 4/67 (5%)

Query: 27   LSDTSIIAVASHCPLLQKVHVGNQDKLTDEG---LKQLGSKCR-ELKDIHFGQCYKISDE 82
            ++D ++  +  H PLL ++ + +   LTD+    L  +GS  R  L +++   C K++D+
Sbjct: 1051 ITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQ 1110

Query: 83   GMIVIAK 89
             +I + +
Sbjct: 1111 TLIYLRR 1117


>gi|54112380 F-box and leucine-rich repeat protein 10 isoform b [Homo
            sapiens]
          Length = 1265

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 8/112 (7%)

Query: 27   LSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQL---GSKCRE-LKDIHFGQCYKISDE 82
            ++D S+  +  H PLL K+H+   + +TD+ +  L   G+  R+ L +I+   C K++D+
Sbjct: 1156 ITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQ 1215

Query: 83   GMIVIAKGCLKLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKG 134
              +   K C  +  I ++  K VT +  + F       Q      CS T  G
Sbjct: 1216 -CLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSSFQ---GRSCSTTRLG 1263



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 194  QNLKELYLVSCKITDYALIAIGRYSMTIETVDVGWCKEITDQGATLI----AQSSKSLRY 249
            +N+ EL L    ITD +L  I R+   +  + + +C  +TDQ   L+      +  SL  
Sbjct: 1144 RNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTE 1203

Query: 250  LGLMRCDKVNE 260
            + L  C+KV +
Sbjct: 1204 INLSDCNKVTD 1214


>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member A [Homo sapiens]
          Length = 249

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 30/111 (27%), Positives = 57/111 (51%), Gaps = 11/111 (9%)

Query: 101 ENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLRHITELDNET- 159
           +N    +  ++   +   EL+++  +   +TS  + +L KL  L  L+L      DN   
Sbjct: 25  DNSRSNEGKLEGLTDEFEELEFLSTINVGLTS--IANLPKLNKLKKLELS-----DNRVS 77

Query: 160 --VMEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCKITD 208
             +  + ++C NL+ LNL  N I +   +E + K+ +NLK L L +C++T+
Sbjct: 78  GGLEVLAEKCPNLTHLNLSGNKIKDLSTIEPL-KKLENLKSLDLFNCEVTN 127


>gi|54112382 F-box and leucine-rich repeat protein 10 isoform a [Homo
            sapiens]
          Length = 1336

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 28/101 (27%), Positives = 53/101 (52%), Gaps = 6/101 (5%)

Query: 27   LSDTSIIAVASHCPLLQKVHVGNQDKLTDEGLKQL---GSKCRE-LKDIHFGQCYKISDE 82
            ++D S+  +  H PLL K+H+   + +TD+ +  L   G+  R+ L +I+   C K++D+
Sbjct: 1225 ITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTEINLSDCNKVTDQ 1284

Query: 83   GMIVIAKGCLKLQRIYMQENKLVTDQSVKAF-AEHCPELQY 122
              +   K C  +  I ++  K VT +  + F AE    +Q+
Sbjct: 1285 -CLSFFKRCGNICHIDLRYCKQVTKEGCEQFIAEMSVSVQF 1324



 Score = 36.2 bits (82), Expect = 0.037
 Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 4/71 (5%)

Query: 194  QNLKELYLVSCKITDYALIAIGRYSMTIETVDVGWCKEITDQGATLI----AQSSKSLRY 249
            +N+ EL L    ITD +L  I R+   +  + + +C  +TDQ   L+      +  SL  
Sbjct: 1213 RNIVELRLAGLDITDASLRLIIRHMPLLSKLHLSYCNHVTDQSINLLTAVGTTTRDSLTE 1272

Query: 250  LGLMRCDKVNE 260
            + L  C+KV +
Sbjct: 1273 INLSDCNKVTD 1283


>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member E isoform 1 [Homo sapiens]
          Length = 268

 Score = 37.0 bits (84), Expect = 0.022
 Identities = 24/87 (27%), Positives = 46/87 (52%), Gaps = 7/87 (8%)

Query: 93  KLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIH-LTKLRNLSSLDLRH 151
           KL+++ + +N  +    ++  AE CP L Y+   G  +     +  L  L+NL SLDL +
Sbjct: 65  KLRKLELSDN--IISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFN 122

Query: 152 --ITELDN--ETVMEIVKRCKNLSSLN 174
             IT L++  E++ E++++   L   +
Sbjct: 123 CEITNLEDYRESIFELLQQITYLDGFD 149



 Score = 35.0 bits (79), Expect = 0.082
 Identities = 31/112 (27%), Positives = 57/112 (50%), Gaps = 13/112 (11%)

Query: 101 ENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETV 160
           +N L  +  ++   +   EL+++        S   + L+ L  L SL+     EL +  +
Sbjct: 25  DNCLCVNGEIEGLNDTFKELEFL--------SMANVELSSLARLPSLNKLRKLELSDNII 76

Query: 161 ---MEIV-KRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCKITD 208
              +E++ ++C NL+ LNL  N I +   VE + +  +NLK L L +C+IT+
Sbjct: 77  SGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEAL-QNLKNLKSLDLFNCEITN 127


>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
           family, member E isoform 3 [Homo sapiens]
          Length = 220

 Score = 37.0 bits (84), Expect = 0.022
 Identities = 24/87 (27%), Positives = 46/87 (52%), Gaps = 7/87 (8%)

Query: 93  KLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIH-LTKLRNLSSLDLRH 151
           KL+++ + +N  +    ++  AE CP L Y+   G  +     +  L  L+NL SLDL +
Sbjct: 17  KLRKLELSDN--IISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFN 74

Query: 152 --ITELDN--ETVMEIVKRCKNLSSLN 174
             IT L++  E++ E++++   L   +
Sbjct: 75  CEITNLEDYRESIFELLQQITYLDGFD 101



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 26/77 (33%), Positives = 44/77 (57%), Gaps = 5/77 (6%)

Query: 136 IHLTKLRNLSSLDLRHITELDNETV---MEIV-KRCKNLSSLNLCLNWIINDRCVEVIAK 191
           + L+ L  L SL+     EL +  +   +E++ ++C NL+ LNL  N I +   VE + +
Sbjct: 4   VELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEAL-Q 62

Query: 192 EGQNLKELYLVSCKITD 208
             +NLK L L +C+IT+
Sbjct: 63  NLKNLKSLDLFNCEITN 79


>gi|28827813 NLR family, pyrin domain containing 14 [Homo sapiens]
          Length = 1093

 Score = 35.8 bits (81), Expect = 0.048
 Identities = 49/219 (22%), Positives = 92/219 (42%), Gaps = 32/219 (14%)

Query: 51  DKLTDEGLKQLGSKCRELKDIHFGQCY--KISDEGMIVIAKGCLKLQRIYMQENKLVTDQ 108
           + L D+G++ L    R  K      CY  ++S E   +   GC  L    +   +L    
Sbjct: 796 NNLLDDGVQLLCEALRHPK------CYLERLSLESCGLTEAGCEYLSLALISNKRLT--- 846

Query: 109 SVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLR--HITELDNETVMEIVKR 166
                   C     +G  G  + S  + H      L SL LR  H T L +E +   +  
Sbjct: 847 ------HLCLADNVLGDGGVKLMSDALQHAQC--TLKSLVLRRCHFTSLSSEYLSTSLLH 898

Query: 167 CKNLSSLNLCLNWIIND---RCVEVIAKEGQNLKELYLVSCKITDYALIAIGRYSM---T 220
            K+L+ L+L  NW+ ++      +V      NL++L L+ C +T+   + +    +    
Sbjct: 899 NKSLTHLDLGSNWLQDNGVKLLCDVFRHPSCNLQDLELMGCVLTNACCLDLASVILNNPN 958

Query: 221 IETVDVGWCKEITDQGATLIAQSSK----SLRYLGLMRC 255
           + ++D+G   ++ D G  ++  + +    +++ LGL  C
Sbjct: 959 LRSLDLG-NNDLQDDGVKILCDALRYPNCNIQRLGLEYC 996


>gi|6912604 acidic nuclear phosphoprotein 32C [Homo sapiens]
          Length = 234

 Score = 34.7 bits (78), Expect = 0.11
 Identities = 30/108 (27%), Positives = 57/108 (52%), Gaps = 9/108 (8%)

Query: 101 ENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLRHITELDNETV 160
           +N    +  ++A  +   EL+++  +   +TS  +  L KL+ L  L+LR    L+    
Sbjct: 25  DNSRSNEGKLEALTDEFEELEFLSKINGGLTS--ISDLPKLK-LRKLELRVSGGLE---- 77

Query: 161 MEIVKRCKNLSSLNLCLNWIINDRCVEVIAKEGQNLKELYLVSCKITD 208
             + ++C NL+ L L  N I +   +E + K+ +NLK L L +C++T+
Sbjct: 78  -VLAEKCPNLTHLYLSGNKIKDLSTIEPL-KQLENLKSLDLFNCEVTN 123



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 4/86 (4%)

Query: 94  LQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIH-LTKLRNLSSLDLRH- 151
           L ++ +++ +L     ++  AE CP L ++   G  +     I  L +L NL SLDL + 
Sbjct: 60  LPKLKLRKLELRVSGGLEVLAEKCPNLTHLYLSGNKIKDLSTIEPLKQLENLKSLDLFNC 119

Query: 152 -ITELDNETVMEIVKRCKNLSSLNLC 176
            +T L N+    + K    L+ L+ C
Sbjct: 120 EVTNL-NDYGENVFKLLLQLTYLDSC 144


>gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens]
          Length = 326

 Score = 33.9 bits (76), Expect = 0.18
 Identities = 29/137 (21%), Positives = 64/137 (46%), Gaps = 2/137 (1%)

Query: 40  PLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYM 99
           PLL+ + +       DE L+ L ++ R L+ +  G  Y++++ G+    +    LQR+ +
Sbjct: 151 PLLECIVLDRVPAFRDEHLQGL-TRFRALRSLVLGGTYRVTETGLDAGLQELSYLQRLEV 209

Query: 100 QENKLVTDQSVKAFAEHCPELQYVGFMGCSVTSKGVIHLTKLRNLSSLDLR-HITELDNE 158
               L  D ++ A + H  +++ +      +++ G+  L  +  L SL L+  +   +  
Sbjct: 210 LGCTLSADSTLLAISRHLRDVRKIRLTVRGLSAPGLAVLEGMPALESLCLQGPLVTPEMP 269

Query: 159 TVMEIVKRCKNLSSLNL 175
           +  EI+  C  +  L +
Sbjct: 270 SPTEILSSCLTMPKLRV 286


>gi|16306584 F-box and leucine-rich repeat protein 3 [Homo sapiens]
          Length = 428

 Score = 33.5 bits (75), Expect = 0.24
 Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 3/105 (2%)

Query: 22  YRCKQLSDTSIIAVASHCP-LLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKIS 80
           Y  + +S   +  V   CP L++ V   N  +  DE L ++  +C+ L  I  G+C ++S
Sbjct: 314 YFGRSVSKDVLGRVGMTCPRLVELVVCANGLRPLDEELIRIAERCKNLSAIGLGEC-EVS 372

Query: 81  DEGMIVIAKGC-LKLQRIYMQENKLVTDQSVKAFAEHCPELQYVG 124
               +   K C  +L ++ + E  L+ DQ       H    +++G
Sbjct: 373 CSAFVEFVKMCGGRLSQLSIMEEVLIPDQKYSLEQIHWEVSKHLG 417


>gi|116268109 nucleotide-binding oligomerization domains 27 [Homo
           sapiens]
          Length = 1866

 Score = 32.7 bits (73), Expect = 0.41
 Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 12/101 (11%)

Query: 90  GCLKLQRIYMQENKLVTDQSVKAFAEHCP---ELQYVGFMGCSVTSKGVIHLTKLRNLSS 146
           GC +++ +  +  K   D   +A +   P    LQ +G  G  +T++G+ HL K   L  
Sbjct: 684 GCGQIENLSFKSRKC-GDAFAEALSRSLPTMGRLQMLGLAGSKITARGISHLVKALPLCP 742

Query: 147 LDLRHITELDNE-------TVMEIVKRCKNLSSLNLCLNWI 180
             L+ ++  DN+        ++E++     L  L+L  N I
Sbjct: 743 -QLKEVSFRDNQLSDQVVLNIVEVLPHLPRLRKLDLSSNSI 782


>gi|55742693 zyg-11 homolog B [Homo sapiens]
          Length = 744

 Score = 32.3 bits (72), Expect = 0.53
 Identities = 28/129 (21%), Positives = 63/129 (48%), Gaps = 5/129 (3%)

Query: 132 SKGVIHLTKLRNLSSLDLRHITELDNETVMEIVKRCKNLSSLNLCLNWIINDRCVEVIAK 191
           ++ +  +  L  L SLD+ + +  D   ++    R K+L+  +L    +   + ++V+ +
Sbjct: 176 NEDLAEVASLPRLESLDISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVV-R 234

Query: 192 EGQNLKELYLVSCK--ITDYALIAIGRYSM--TIETVDVGWCKEITDQGATLIAQSSKSL 247
           E ++L  L +   K   +D AL  + +  +   + ++DV   K +TD+      Q   S+
Sbjct: 235 ELKHLNHLDISDDKQFTSDIALRLLEQKDILPNLVSLDVSGRKHVTDKAVEAFIQQRPSM 294

Query: 248 RYLGLMRCD 256
           +++GL+  D
Sbjct: 295 QFVGLLATD 303


>gi|16306574 F-box and leucine-rich repeat protein 5 isoform 2 [Homo
           sapiens]
          Length = 565

 Score = 31.6 bits (70), Expect = 0.91
 Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 3/74 (4%)

Query: 24  CKQLSDTS--IIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISD 81
           C Q++D    ++ +    P L+ +++     +T  GL+ L S C  L D +F  C  I+ 
Sbjct: 482 CYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNING 541

Query: 82  EGMIVIAKGCLKLQ 95
                 A GC  LQ
Sbjct: 542 PHADT-ASGCQNLQ 554


>gi|16306572 F-box and leucine-rich repeat protein 5 isoform 1 [Homo
           sapiens]
          Length = 691

 Score = 31.6 bits (70), Expect = 0.91
 Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 3/74 (4%)

Query: 24  CKQLSDTS--IIAVASHCPLLQKVHVGNQDKLTDEGLKQLGSKCRELKDIHFGQCYKISD 81
           C Q++D    ++ +    P L+ +++     +T  GL+ L S C  L D +F  C  I+ 
Sbjct: 608 CYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNING 667

Query: 82  EGMIVIAKGCLKLQ 95
                 A GC  LQ
Sbjct: 668 PHADT-ASGCQNLQ 680


>gi|16306576 F-box and leucine-rich repeat protein 6 isoform 1 [Homo
           sapiens]
          Length = 539

 Score = 31.6 bits (70), Expect = 0.91
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 2/61 (3%)

Query: 93  KLQRIYMQENKLVTDQSVKAFAEHCPELQYVGFMGC-SVTSKGVIHLTK-LRNLSSLDLR 150
           +LQR+ +   K      +K   E CP L ++   GC  VT+  ++ L K    L SLDL+
Sbjct: 195 QLQRLTLIHWKSQVHPVLKLVGECCPRLTFLKLSGCHGVTADALVMLAKACCQLHSLDLQ 254

Query: 151 H 151
           H
Sbjct: 255 H 255


>gi|239754160 PREDICTED: similar to hCG1980490 [Homo sapiens]
          Length = 348

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 26/75 (34%), Positives = 39/75 (52%), Gaps = 12/75 (16%)

Query: 50  QDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQS 109
           +D LTD GL QLG   REL+     Q  ++ ++  I I +   KL+  ++++ + V D  
Sbjct: 199 EDTLTDSGLSQLGRALRELE----AQRQRLREQHQIWIRE---KLK--HLEQKEEVADDQ 249

Query: 110 VK---AFAEHCPELQ 121
           VK   A  E C E Q
Sbjct: 250 VKGLVAEEEACEERQ 264


>gi|239748674 PREDICTED: similar to hCG1980490 [Homo sapiens]
          Length = 348

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 26/75 (34%), Positives = 39/75 (52%), Gaps = 12/75 (16%)

Query: 50  QDKLTDEGLKQLGSKCRELKDIHFGQCYKISDEGMIVIAKGCLKLQRIYMQENKLVTDQS 109
           +D LTD GL QLG   REL+     Q  ++ ++  I I +   KL+  ++++ + V D  
Sbjct: 199 EDTLTDSGLSQLGRALRELE----AQRQRLREQHQIWIRE---KLK--HLEQKEEVADDQ 249

Query: 110 VK---AFAEHCPELQ 121
           VK   A  E C E Q
Sbjct: 250 VKGLVAEEEACEERQ 264


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,164,138
Number of Sequences: 37866
Number of extensions: 401455
Number of successful extensions: 1252
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 998
Number of HSP's gapped (non-prelim): 131
length of query: 303
length of database: 18,247,518
effective HSP length: 102
effective length of query: 201
effective length of database: 14,385,186
effective search space: 2891422386
effective search space used: 2891422386
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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