Search of human proteins with 253735691

Search of human proteins with 253735691

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|253735691 5-hydroxytryptamine (serotonin) receptor 3A
isoform c [Homo sapiens]
         (463 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|253735691 5-hydroxytryptamine (serotonin) receptor 3A isoform...   944   0.0  
gi|253735700 5-hydroxytryptamine (serotonin) receptor 3A isoform...   930   0.0  
gi|253735697 5-hydroxytryptamine (serotonin) receptor 3A isoform...   914   0.0  
gi|5174469 5-hydroxytryptamine (serotonin) receptor 3B precursor...   372   e-103
gi|47519913 5-hydroxytryptamine receptor 3 subunit E [Homo sapiens]   294   1e-79
gi|47519867 5-hydroxytryptamine receptor 3 subunit C [Homo sapiens]   284   1e-76
gi|11138123 cholinergic receptor, nicotinic, alpha 10 [Homo sapi...   229   4e-60
gi|4757982 cholinergic receptor, nicotinic, alpha 6 [Homo sapiens]    219   5e-57
gi|4502835 cholinergic receptor, nicotinic, beta polypeptide 3 [...   215   6e-56
gi|70995130 cholinergic receptor, nicotinic, alpha 9 precursor [...   214   2e-55
gi|4502833 neuronal nicotinic acetylcholine receptor beta 2 prec...   213   2e-55
gi|33589827 cholinergic receptor, nicotinic, alpha 5 [Homo sapiens]   213   4e-55
gi|4502827 cholinergic receptor, nicotinic, alpha 4 subunit prec...   211   1e-54
gi|4502831 cholinergic receptor, nicotinic, alpha 7 precursor [H...   207   2e-53
gi|153792669 cholinergic receptor, nicotinic, alpha polypeptide ...   204   1e-52
gi|4502837 cholinergic receptor, nicotinic, beta 4 [Homo sapiens]     204   2e-52
gi|4557457 nicotinic cholinergic receptor alpha 1 isoform b prec...   201   1e-51
gi|19923122 cholinergic receptor, nicotinic, alpha 3 [Homo sapiens]   198   8e-51
gi|87567783 nicotinic cholinergic receptor alpha 1 isoform a pre...   187   2e-47
gi|41327726 nicotinic acetylcholine receptor beta 1 subunit prec...   186   3e-47
gi|4557461 nicotinic acetylcholine receptor delta polypeptide pr...   176   4e-44
gi|4557463 nicotinic acetylcholine receptor epsilon polypeptide ...   164   2e-40
gi|223468705 5-hydroxytryptamine receptor 3 subunit D isoform 1 ...   144   2e-34
gi|61743914 cholinergic receptor, nicotinic, gamma polypeptide p...   144   2e-34
gi|23312388 CHRNA7-FAM7A fusion isoform 1 [Homo sapiens]              139   4e-33
gi|47519877 5-hydroxytryptamine receptor 3 subunit D isoform 2 [...   117   3e-26
gi|23312390 CHRNA7-FAM7A fusion isoform 2 [Homo sapiens]              113   3e-25
gi|206725456 zinc activated ligand-gated ion channel [Homo sapiens]   105   1e-22
gi|157743288 gamma-aminobutyric acid (GABA) receptor, rho 3 [Hom...    88   2e-17
gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo s...    86   7e-17

>gi|253735691 5-hydroxytryptamine (serotonin) receptor 3A isoform c
           [Homo sapiens]
          Length = 463

 Score =  944 bits (2439), Expect = 0.0
 Identities = 463/463 (100%), Positives = 463/463 (100%)

Query: 1   MHRSFLQARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDE 60
           MHRSFLQARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDE
Sbjct: 1   MHRSFLQARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDE 60

Query: 61  KNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIP 120
           KNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIP
Sbjct: 61  KNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIP 120

Query: 121 YVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEK 180
           YVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEK
Sbjct: 121 YVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEK 180

Query: 181 VKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIF 240
           VKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIF
Sbjct: 181 VKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIF 240

Query: 241 LMVMDIVGFYLPPNSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMAL 300
           LMVMDIVGFYLPPNSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMAL
Sbjct: 241 LMVMDIVGFYLPPNSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMAL 300

Query: 301 LVISLAETIFIVRLVHKQDLQQPVPAWLRHLVLERIAWLLCLREQSTSQRPPATSQATKT 360
           LVISLAETIFIVRLVHKQDLQQPVPAWLRHLVLERIAWLLCLREQSTSQRPPATSQATKT
Sbjct: 301 LVISLAETIFIVRLVHKQDLQQPVPAWLRHLVLERIAWLLCLREQSTSQRPPATSQATKT 360

Query: 361 DDCSAMGNHCSHMGGPQDFEKSPRDRCSPPPPPREASLAVCGLLQELSSIRQFLEKRDEI 420
           DDCSAMGNHCSHMGGPQDFEKSPRDRCSPPPPPREASLAVCGLLQELSSIRQFLEKRDEI
Sbjct: 361 DDCSAMGNHCSHMGGPQDFEKSPRDRCSPPPPPREASLAVCGLLQELSSIRQFLEKRDEI 420

Query: 421 REVARDWLRVGSVLDKLLFHIYLLAVLAYSITLVMLWSIWQYA 463
           REVARDWLRVGSVLDKLLFHIYLLAVLAYSITLVMLWSIWQYA
Sbjct: 421 REVARDWLRVGSVLDKLLFHIYLLAVLAYSITLVMLWSIWQYA 463


>gi|253735700 5-hydroxytryptamine (serotonin) receptor 3A isoform b
           precursor [Homo sapiens]
          Length = 484

 Score =  930 bits (2404), Expect = 0.0
 Identities = 456/457 (99%), Positives = 457/457 (100%)

Query: 7   QARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLT 66
           +ARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLT
Sbjct: 28  EARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLT 87

Query: 67  TYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRH 126
           TYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRH
Sbjct: 88  TYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRH 147

Query: 127 QGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRS 186
           QGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRS
Sbjct: 148 QGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRS 207

Query: 187 VFMNQGEWELLGVLPYFREFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDI 246
           VFMNQGEWELLGVLPYFREFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDI
Sbjct: 208 VFMNQGEWELLGVLPYFREFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDI 267

Query: 247 VGFYLPPNSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLA 306
           VGFYLPPNSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLA
Sbjct: 268 VGFYLPPNSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLA 327

Query: 307 ETIFIVRLVHKQDLQQPVPAWLRHLVLERIAWLLCLREQSTSQRPPATSQATKTDDCSAM 366
           ETIFIVRLVHKQDLQQPVPAWLRHLVLERIAWLLCLREQSTSQRPPATSQATKTDDCSAM
Sbjct: 328 ETIFIVRLVHKQDLQQPVPAWLRHLVLERIAWLLCLREQSTSQRPPATSQATKTDDCSAM 387

Query: 367 GNHCSHMGGPQDFEKSPRDRCSPPPPPREASLAVCGLLQELSSIRQFLEKRDEIREVARD 426
           GNHCSHMGGPQDFEKSPRDRCSPPPPPREASLAVCGLLQELSSIRQFLEKRDEIREVARD
Sbjct: 388 GNHCSHMGGPQDFEKSPRDRCSPPPPPREASLAVCGLLQELSSIRQFLEKRDEIREVARD 447

Query: 427 WLRVGSVLDKLLFHIYLLAVLAYSITLVMLWSIWQYA 463
           WLRVGSVLDKLLFHIYLLAVLAYSITLVMLWSIWQYA
Sbjct: 448 WLRVGSVLDKLLFHIYLLAVLAYSITLVMLWSIWQYA 484


>gi|253735697 5-hydroxytryptamine (serotonin) receptor 3A isoform a
           precursor [Homo sapiens]
          Length = 516

 Score =  914 bits (2361), Expect = 0.0
 Identities = 456/489 (93%), Positives = 457/489 (93%), Gaps = 32/489 (6%)

Query: 7   QARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLT 66
           +ARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLT
Sbjct: 28  EARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLT 87

Query: 67  TYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRH 126
           TYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRH
Sbjct: 88  TYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRH 147

Query: 127 QGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRS 186
           QGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRS
Sbjct: 148 QGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRS 207

Query: 187 VFMNQGEWELLGVLPYFREFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDI 246
           VFMNQGEWELLGVLPYFREFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDI
Sbjct: 208 VFMNQGEWELLGVLPYFREFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDI 267

Query: 247 VGFYLPPNSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLI---------------- 290
           VGFYLPPNSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLI                
Sbjct: 268 VGFYLPPNSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGKAPPGSRAQSGEKPA 327

Query: 291 ----------------GVYFVVCMALLVISLAETIFIVRLVHKQDLQQPVPAWLRHLVLE 334
                           GVYFVVCMALLVISLAETIFIVRLVHKQDLQQPVPAWLRHLVLE
Sbjct: 328 PSHLLHVSLASALGCTGVYFVVCMALLVISLAETIFIVRLVHKQDLQQPVPAWLRHLVLE 387

Query: 335 RIAWLLCLREQSTSQRPPATSQATKTDDCSAMGNHCSHMGGPQDFEKSPRDRCSPPPPPR 394
           RIAWLLCLREQSTSQRPPATSQATKTDDCSAMGNHCSHMGGPQDFEKSPRDRCSPPPPPR
Sbjct: 388 RIAWLLCLREQSTSQRPPATSQATKTDDCSAMGNHCSHMGGPQDFEKSPRDRCSPPPPPR 447

Query: 395 EASLAVCGLLQELSSIRQFLEKRDEIREVARDWLRVGSVLDKLLFHIYLLAVLAYSITLV 454
           EASLAVCGLLQELSSIRQFLEKRDEIREVARDWLRVGSVLDKLLFHIYLLAVLAYSITLV
Sbjct: 448 EASLAVCGLLQELSSIRQFLEKRDEIREVARDWLRVGSVLDKLLFHIYLLAVLAYSITLV 507

Query: 455 MLWSIWQYA 463
           MLWSIWQYA
Sbjct: 508 MLWSIWQYA 516


>gi|5174469 5-hydroxytryptamine (serotonin) receptor 3B precursor
           [Homo sapiens]
          Length = 441

 Score =  372 bits (955), Expect = e-103
 Identities = 191/449 (42%), Positives = 278/449 (61%), Gaps = 47/449 (10%)

Query: 18  ALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTD 77
           AL  LS  LL  Y K VRPV +W K TTV +D+ V+AIL+VD +NQ+L T +WY++ W D
Sbjct: 31  ALYHLSKQLLQKYHKEVRPVYNWTKATTVYLDLFVHAILDVDAENQILKTSVWYQEVWND 90

Query: 78  EFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRHQGEVQNYKPLQ 137
           EFL WN   FD I ++S+P  +IW PDI+INEFVD+ + P++PYVY+   G ++NYKP+Q
Sbjct: 91  EFLSWNSSMFDEIREISLPLSAIWAPDIIINEFVDIERYPDLPYVYVNSSGTIENYKPIQ 150

Query: 138 VVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELL 197
           VV+ACSL+ Y FPFDVQNCSLTF S LHT++D++++  R PE ++ D+  F+N  EWELL
Sbjct: 151 VVSACSLETYAFPFDVQNCSLTFKSILHTVEDVDLAFLRSPEDIQHDKKAFLNDSEWELL 210

Query: 198 GVLPYFREFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNSGE 257
            V   +      S+  +A+++F VV+RR PL YVVSLL+PSIFLM++D+  FYLPPN   
Sbjct: 211 SVSSTY-SILQSSAGGFAQIQFNVVMRRHPLVYVVSLLIPSIFLMLVDLGSFYLPPNCRA 269

Query: 258 RVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHK 317
           R+ FK ++L+GY+VF + +S+ +P +   TPLIG +F +CMA LV+SLA++I +V+ +H 
Sbjct: 270 RIVFKTSVLVGYTVFRVNMSNQVPRSVGSTPLIGHFFTICMAFLVLSLAKSIVLVKFLHD 329

Query: 318 QD---LQQPVPAWLRHLVLERIAWLLCLREQSTSQRP---PATSQATKTDDCSAMGNHCS 371
           +     +QP                LCLR  + + RP   P   +A  T+  S  G H +
Sbjct: 330 EQRGGQEQP---------------FLCLRGDTDADRPRVEPRAQRAVVTES-SLYGEHLA 373

Query: 372 HMGGPQDFEKSPRDRCSPPPPPREASLAVCGLLQELSSIRQFLEKRDEIREVARDWLRVG 431
             G  ++                        +  +L SI  +L+ +D+  +   +WL + 
Sbjct: 374 QPGTLKE------------------------VWSQLQSISNYLQTQDQTDQQEAEWLVLL 409

Query: 432 SVLDKLLFHIYLLAVLAYSITLVMLWSIW 460
           S  D+LLF  YL  +  Y+ITL  LW++W
Sbjct: 410 SRFDRLLFQSYLFMLGIYTITLCSLWALW 438


>gi|47519913 5-hydroxytryptamine receptor 3 subunit E [Homo sapiens]
          Length = 471

 Score =  294 bits (752), Expect = 1e-79
 Identities = 169/433 (39%), Positives = 254/433 (58%), Gaps = 33/433 (7%)

Query: 31  RKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNI 90
           RK  RPV +   PT V+I   + AIL+V+E+  +L++++W    W + F+ WNPE+ + I
Sbjct: 66  RKPFRPVTNISVPTQVNISFAMSAILDVNEQLHLLSSFLWLEMVWDNPFISWNPEECEGI 125

Query: 91  TKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFP 150
           TK+S+   ++W+PDI I E +DV K+P     Y+ ++G ++  KP++V + C+LDI+ FP
Sbjct: 126 TKMSMAAKNLWLPDIFIIELMDVDKTPKGLTAYVSNEGRIRYKKPMKVDSICNLDIFYFP 185

Query: 151 FDVQNCSLTFTSWLHTIQ----DINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFREF 206
           FD QNC+LTF+S+L+T+     D+   +W + +   + R++    GEWELLG+     + 
Sbjct: 186 FDQQNCTLTFSSFLYTVDSMLLDMEKEVWEITD---ASRNILQTHGEWELLGLSKATAKL 242

Query: 207 SMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNSGERVSFKITLL 266
           S    N Y ++ FYV IRRRP  YV++LL+PS FL+ +D + FYLP  SG RV FKITLL
Sbjct: 243 S-RGGNLYDQIVFYVAIRRRPSLYVINLLVPSGFLVAIDALSFYLPVKSGNRVPFKITLL 301

Query: 267 LGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQDLQ-QPVP 325
           LGY+VFL+++SD LP +  GTPLIGVYF +C++L+V SL ETIFI  L+H    Q  P+P
Sbjct: 302 LGYNVFLLMMSDLLPTS--GTPLIGVYFALCLSLMVGSLLETIFITHLLHVATTQPPPLP 359

Query: 326 AWLRHLVLERIAWLLCLREQSTSQRPPATSQATKTDDCSAMGNHCSHMGGPQDFEKSPRD 385
            WL  L+L   +   C         P A  +  K       G   +H+ G     K P  
Sbjct: 360 RWLHSLLLHCNSPGRCC--------PTAPQKENK-----GPGLTPTHLPG----VKEPEV 402

Query: 386 RCSPPPPPREASLAVCGLLQELSSIRQFLEKRDEIREVARDWLRVGSVLDKLLFHIYLLA 445
                P P EA L   G  +   + R+   ++    E+   WL+    +D +LF +YLL 
Sbjct: 403 SAGQMPGPAEAELT--GGSEWTRAQREHEAQKQHSVEL---WLQFSHAMDAMLFRLYLLF 457

Query: 446 VLAYSITLVMLWS 458
           + +  IT++ LW+
Sbjct: 458 MASSIITVICLWN 470


>gi|47519867 5-hydroxytryptamine receptor 3 subunit C [Homo sapiens]
          Length = 447

 Score =  284 bits (726), Expect = 1e-76
 Identities = 161/433 (37%), Positives = 252/433 (58%), Gaps = 42/433 (9%)

Query: 31  RKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNI 90
           RK  RP  ++  PT V+I   + AIL VD + Q+LT+++W    W + F+ WNP++   I
Sbjct: 51  RKAFRPFTNYSIPTRVNISFTLSAILGVDAQLQLLTSFLWMDLVWDNPFINWNPKECVGI 110

Query: 91  TKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFP 150
            KL++  +++W+PDI I E +DV ++P+    YI  +G ++  KP++V + C+LDI+ FP
Sbjct: 111 NKLTVLAENLWLPDIFIVESMDVDQTPSGLTAYISSEGRIKYDKPMRVTSICNLDIFYFP 170

Query: 151 FDVQNCSLTFTSWLHTIQDINISL----WRLPEKVKSDRSVFMNQGEWELLGVLPYFREF 206
           FD QNC+ TF+S+L+T+  + + +    W + +   + R V   QGEWELLG+     + 
Sbjct: 171 FDQQNCTFTFSSFLYTVDSMLLGMDKEVWEITD---TSRKVIQTQGEWELLGINKATPKM 227

Query: 207 SMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNSGERVSFKITLL 266
           SM  +N Y ++ FYV IRRRP  Y+++LL+PS FL+ +D + FYLP  S  R  FKITLL
Sbjct: 228 SM-GNNLYDQIMFYVAIRRRPSLYIINLLVPSSFLVAIDALSFYLPAESENRAPFKITLL 286

Query: 267 LGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQDLQ-QPVP 325
           LGY+VFL++++D LPA+  GTPLI VYF +C++L+V+SL ET+FI  L+H    Q  P+P
Sbjct: 287 LGYNVFLLMMNDLLPAS--GTPLISVYFALCLSLMVVSLLETVFITYLLHVATTQPPPMP 344

Query: 326 AWLRHLVLERIAWLLCLREQSTSQRPPATSQATKTDDCSAMGNHCSHMGGPQDFEKSPRD 385
            WL  L+L   +   C         P A  +  K      +G   +H+ GP    K P +
Sbjct: 345 RWLHSLLLHCTSPGRCC--------PTAPQKGNK-----GLGLTLTHLPGP----KEPGE 387

Query: 386 RCSPPPPPREASLAVCGLLQELSSIRQFLEKRDEIREVARDWLRVGSVLDKLLFHIYLLA 445
                  PRE          E      +   + ++ E+   W++    +D LLF +YLL 
Sbjct: 388 LAGKKLGPRET---------EPDGGSGW--TKTQLMEL---WVQFSHAMDTLLFRLYLLF 433

Query: 446 VLAYSITLVMLWS 458
           + +  +T+++LW+
Sbjct: 434 MASSILTVIVLWN 446


>gi|11138123 cholinergic receptor, nicotinic, alpha 10 [Homo
           sapiens]
          Length = 450

 Score =  229 bits (584), Expect = 4e-60
 Identities = 138/444 (31%), Positives = 226/444 (50%), Gaps = 35/444 (7%)

Query: 20  LRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEF 79
           L+L   L  NY   +RPV D  +   V+++V +  I+++DE+NQVLT Y+W RQ WTD +
Sbjct: 31  LKLFRDLFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTLYLWIRQEWTDAY 90

Query: 80  LQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNI-PYVYIRHQGEVQNYKPLQV 138
           L+W+P  +  +  + IP+  +W PDI++    D     +    V +RH G V+   P   
Sbjct: 91  LRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSASTNVVLRHDGAVRWDAPAIT 150

Query: 139 VTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLG 198
            ++C +D+  FPFD Q+C LTF SW H    +++     P    +  + F+   EW +LG
Sbjct: 151 RSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVR----PRGAAASLADFVENVEWRVLG 206

Query: 199 VLPYFREFSME-SSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNSGE 257
           +    R  +    S  Y ++ F +++RRR   YV +LLLP + + ++  + F+LP +SGE
Sbjct: 207 MPARRRVLTYGCCSEPYPDVTFTLLLRRRAAAYVCNLLLPCVLISLLAPLAFHLPADSGE 266

Query: 258 RVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHK 317
           +VS  +T+LL  +VF +++++++P  A   PLIG Y++  M ++  S A TI I+ L + 
Sbjct: 267 KVSLGVTVLLALTVFQLLLAESMP-PAESVPLIGKYYMATMTMVTFSTALTILIMNLHYC 325

Query: 318 QDLQQPVPAWLRHLVLERIAWLLCLREQST---SQRPPATSQATKTDDCSAMGNHCSHMG 374
               +PVPAW R L+L  +A  LC+RE+       RPP  S +                 
Sbjct: 326 GPSVRPVPAWARALLLGHLARGLCVRERGEPCGQSRPPELSPS----------------- 368

Query: 375 GPQDFEKSPRDRCSPPPPPREASLAVC---GLLQELSSIRQFLEKRDEIREVARDWLRVG 431
            PQ    SP     PP  P      +C    LL  +++I          +    DW R+ 
Sbjct: 369 -PQ----SPEGGAGPPAGPCHEPRCLCRQEALLHHVATIANTFRSHRAAQRCHEDWKRLA 423

Query: 432 SVLDKLLFHIYLLAVLAYSITLVM 455
            V+D+    I+    L  S+ +++
Sbjct: 424 RVMDRFFLAIFFSMALVMSLLVLV 447


>gi|4757982 cholinergic receptor, nicotinic, alpha 6 [Homo sapiens]
          Length = 494

 Score =  219 bits (557), Expect = 5e-57
 Identities = 125/447 (27%), Positives = 230/447 (51%), Gaps = 32/447 (7%)

Query: 21  RLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFL 80
           RL   L ++Y + +RPV +   P TV  +V +  + NVDE NQ++ T +W R  W D  L
Sbjct: 36  RLFHKLFSHYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKL 95

Query: 81  QWNPEDFDNITKLSIPTDSIWVPDIL-----INEFVDVGKSPNIPYVYIRHQGEVQNYKP 135
           +W+P ++D I  L +P D IW PDI+     + +F   GK+  +    +++ G +    P
Sbjct: 96  RWDPMEYDGIETLRVPADKIWKPDIVLYNNAVGDFQVEGKTKAL----LKYNGMITWTPP 151

Query: 136 LQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWE 195
               ++C +DI  FPFD QNCSL F SW +   +I++ +  +  KV  D + F    EWE
Sbjct: 152 AIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLI--IGSKV--DMNDFWENSEWE 207

Query: 196 LLGVLPYFREFSMES-SNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPN 254
           ++    Y  +         Y ++ +   IRR P+FY ++L++P +F+  + ++ FYLP +
Sbjct: 208 IIDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSD 267

Query: 255 SGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRL 314
            GE+V+  I++LL  +VFL+++++T+P+T++  PL+G Y +  M  + +S+  T+F++ +
Sbjct: 268 CGEKVTLCISVLLSLTVFLLVITETIPSTSLVVPLVGEYLLFTMIFVTLSIVVTVFVLNI 327

Query: 315 VHKQDLQQPVPAWLRHLVLERIAWLLCLREQSTSQR-------PPATSQATKTDDCSAMG 367
            ++      +P W++ + L+ +  +L +R      R       P   ++       ++ G
Sbjct: 328 HYRTPTTHTMPRWVKTVFLKLLPQVLLMRWPLDKTRGTGSDAVPRGLARRPAKGKLASHG 387

Query: 368 -----NHCSHMGGPQDFEKSPRDRCSPPP-----PPREASLAVCGLLQELSSIRQFLEKR 417
                  C H     +   S R R S  P        E S  V  ++  +  I + ++  
Sbjct: 388 EPRHLKECFHCHKSNELATSKR-RLSHQPLQWVVENSEHSPEVEDVINSVQFIAENMKSH 446

Query: 418 DEIREVARDWLRVGSVLDKLLFHIYLL 444
           +E +EV  DW  V  V+D++   ++++
Sbjct: 447 NETKEVEDDWKYVAMVVDRVFLWVFII 473


>gi|4502835 cholinergic receptor, nicotinic, beta polypeptide 3
           [Homo sapiens]
          Length = 458

 Score =  215 bits (548), Expect = 6e-56
 Identities = 126/438 (28%), Positives = 226/438 (51%), Gaps = 25/438 (5%)

Query: 18  ALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTD 77
           ALLR   +L   Y+K VRPV        V   + +  +++VDEKNQ++TT +W +Q WTD
Sbjct: 31  ALLR---HLFQGYQKWVRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTD 87

Query: 78  EFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVG-KSPNIPYVYIRHQGEVQNYKPL 136
             L+WNP+D+  I  + +P++S+W+PDI++ E  D   +   +  V ++  G V    P 
Sbjct: 88  HKLRWNPDDYGGIHSIKVPSESLWLPDIVLFENADGRFEGSLMTKVIVKSNGTVVWTPPA 147

Query: 137 QVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWEL 196
              ++C++D+  FPFD QNCS+ F SW  T     + L  + E V  DR  F + GEWE+
Sbjct: 148 SYKSSCTMDVTFFPFDRQNCSMKFGSW--TYDGTMVDLILINENV--DRKDFFDNGEWEI 203

Query: 197 LGVLPYFREFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNSG 256
           L      +    +    Y  + +  V+RR PLFY + L++P + L  + ++ FYLP + G
Sbjct: 204 LNA-KGMKGNRRDGVYSYPFITYSFVLRRLPLFYTLFLIIPCLGLSFLTVLVFYLPSDEG 262

Query: 257 ERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVH 316
           E++S   ++L+  +VFL+++ + +P+++   PLIG Y +  M  + +S+  T+F++ + H
Sbjct: 263 EKLSLSTSVLVSLTVFLLVIEEIIPSSSKVIPLIGEYLLFIMIFVTLSIIVTVFVINVHH 322

Query: 317 K-QDLQQPVPAWLRHLVLERIAWLLCLREQSTSQRPPATSQATKTDDCSAMGNHCSHMGG 375
           +      P+  W++ L L+++  LLC+++       P   ++        +         
Sbjct: 323 RSSSTYHPMAPWVKRLFLQKLPKLLCMKDHVDRYSSPEKEESQPVVKGKVL--------- 373

Query: 376 PQDFEKSPRDRCSPPPPPREASLAVCGLLQELSSIRQFLEKRDEIREVARDWLRVGSVLD 435
               EK  + + S       A L        +  I + ++K   I +V +DW  V  VLD
Sbjct: 374 ----EKKKQKQLSDGEKVLVAFLEKAA--DSIRYISRHVKKEHFISQVVQDWKFVAQVLD 427

Query: 436 KLLFHIYLLAVLAYSITL 453
           ++   ++L+  +  S+ +
Sbjct: 428 RIFLWLFLIVSVTGSVLI 445


>gi|70995130 cholinergic receptor, nicotinic, alpha 9 precursor
           [Homo sapiens]
          Length = 479

 Score =  214 bits (544), Expect = 2e-55
 Identities = 131/449 (29%), Positives = 225/449 (50%), Gaps = 21/449 (4%)

Query: 21  RLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFL 80
           +L + L  +Y   +RPV D  K   V++ + +  I ++DE+NQ+LT Y+W RQ W D +L
Sbjct: 33  KLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYLWIRQIWHDAYL 92

Query: 81  QWNPEDFDNITKLSIPTDSIWVPDI-LINEFVDVGKSPNIPYVYIRHQGEVQNYKPLQVV 139
            W+ + +D +  + IP+D +W PDI L N+  D    P    V +R+ G +    P    
Sbjct: 93  TWDRDQYDGLDSIRIPSDLVWRPDIVLYNKADDESSEPVNTNVVLRYDGLITWDAPAITK 152

Query: 140 TACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGV 199
           ++C +D+  FPFD Q C+LTF SW +    ++I           D S F+   EWE+ G+
Sbjct: 153 SSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDI----FNALDSGDLSDFIEDVEWEVHGM 208

Query: 200 LPYFREFSME-SSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNSGER 258
                  S    S  Y ++ F ++++RR  FY+V+LL+P + +  +  + FYLP  SGE+
Sbjct: 209 PAVKNVISYGCCSEPYPDVTFTLLLKRRSSFYIVNLLIPCVLISFLAPLSFYLPAASGEK 268

Query: 259 VSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQ 318
           VS  +T+LL  +VF ++V++ +PA+    PLIG Y++  MAL+  S A TI ++ +    
Sbjct: 269 VSLGVTILLAMTVFQLMVAEIMPASE-NVPLIGKYYIATMALITASTALTIMVMNIHFCG 327

Query: 319 DLQQPVPAWLRHLVLERIAWLL--------CLREQSTSQRPPATSQATKTDDCSAMGNHC 370
              +PVP W R ++L+ ++ +L        CL    + +R   T   +K  + +      
Sbjct: 328 AEARPVPHWARVVILKYMSRVLFVYDVGESCLSPHHSRERDHLTKVYSKLPESNLKAARN 387

Query: 371 SHMGGPQDFEKS-PRDRCSPPPPPREASLAVCG----LLQELSSIRQFLEKRDEIREVAR 425
             +   +D  K    D       P+EA  + C     L + +  I + L+          
Sbjct: 388 KDLSRKKDMNKRLKNDLGCQGKNPQEAE-SYCAQYKVLTRNIEYIAKCLKDHKATNSKGS 446

Query: 426 DWLRVGSVLDKLLFHIYLLAVLAYSITLV 454
           +W +V  V+D+    I+ + V   +I ++
Sbjct: 447 EWKKVAKVIDRFFMWIFFIMVFVMTILII 475


>gi|4502833 neuronal nicotinic acetylcholine receptor beta 2
           precursor [Homo sapiens]
          Length = 502

 Score =  213 bits (543), Expect = 2e-55
 Identities = 124/458 (27%), Positives = 233/458 (50%), Gaps = 32/458 (6%)

Query: 21  RLSDYLL--TNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDE 78
           RL ++LL  + Y K +RP  +  +  TV + V +  +++V E+ Q++TT +W  Q W D 
Sbjct: 31  RLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDY 90

Query: 79  FLQWNPEDFDNITKLSIPTDSIWVPDILINEFVD-VGKSPNIPYVYIRHQGEVQNYKPLQ 137
            L W PE+FDN+ K+ +P+  IW+PD+++    D + +        + + G +    P  
Sbjct: 91  RLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAI 150

Query: 138 VVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELL 197
             +AC +++ +FPFD QNC++ F SW +   +I++ L    +   +    F   GEW+++
Sbjct: 151 YKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVL----KSEVASLDDFTPSGEWDIV 206

Query: 198 GVLPYFREFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNSGE 257
             LP  R  + + S Y  ++ +  +IRR+PLFY ++L++P + +  + I+ FYLP + GE
Sbjct: 207 A-LPGRRNENPDDSTY-VDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCGE 264

Query: 258 RVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHK 317
           +++  I++LL  +VFL+++S  +P T++  PL+G Y +  M L+  S+  ++ ++ + H+
Sbjct: 265 KMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCVLNVHHR 324

Query: 318 QDLQQPVPAWLRHLVLERIAWLL--------CLREQSTSQRPPAT---------SQATKT 360
                 +  W++ + LE++  LL        C R++   +R              +A   
Sbjct: 325 SPTTHTMAPWVKVVFLEKLPALLFMQQPRHHCARQRLRLRRRQREREGAGALFFREAPGA 384

Query: 361 DDCSAMGNHCSHMGGPQDFEKSPRDRCSPPPPPREASLAVCGLLQELSSIR---QFLEKR 417
           D C+   N  S  G    F   P        P R      CGL + +  +R     +   
Sbjct: 385 DSCTCFVNRASVQGLAGAFGAEPAPVAG---PGRSGEPCGCGLREAVDGVRFIADHMRSE 441

Query: 418 DEIREVARDWLRVGSVLDKLLFHIYLLAVLAYSITLVM 455
           D+ + V+ DW  V  V+D+L   I++   +  +I + +
Sbjct: 442 DDDQSVSEDWKYVAMVIDRLFLWIFVFVCVFGTIGMFL 479


>gi|33589827 cholinergic receptor, nicotinic, alpha 5 [Homo sapiens]
          Length = 468

 Score =  213 bits (541), Expect = 4e-55
 Identities = 121/429 (28%), Positives = 213/429 (49%), Gaps = 37/429 (8%)

Query: 26  LLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPE 85
           L  +Y + VRPV        +   + +  +++VDEKNQ++TT +W +Q W D  L+WNP+
Sbjct: 54  LFQDYERWVRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPD 113

Query: 86  DFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRHQGEVQNYKPLQVVTACSLD 145
           D+  I  + +P+DS+W PDI++ +  D           IR+ G V    P    ++C++D
Sbjct: 114 DYGGIKVIRVPSDSVWTPDIVLFDNADGRFEGTSTKTVIRYNGTVTWTPPANYKSSCTID 173

Query: 146 IYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFRE 205
           +  FPFD+QNCS+ F SW +    ++I L    E    D+  F + GEWE++      + 
Sbjct: 174 VTFFPFDLQNCSMKFGSWTYDGSQVDIIL----EDQDVDKRDFFDNGEWEIVSATGS-KG 228

Query: 206 FSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNSGERVSFKITL 265
              +S  +Y  + +  VI+R PLFY + L++P I L  + ++ FYLP N GE++    ++
Sbjct: 229 NRTDSCCWYPYVTYSFVIKRLPLFYTLFLIIPCIGLSFLTVLVFYLPSNEGEKICLCTSV 288

Query: 266 LLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQDLQQPVP 325
           L+  +VFL+++ + +P+++   PLIG Y V  M  + +S+  T+F + + H+        
Sbjct: 289 LVSLTVFLLVIEEIIPSSSKVIPLIGEYLVFTMIFVTLSIMVTVFAINIHHRSSSTHNAM 348

Query: 326 AWL-RHLVLERIAWLLCLREQSTSQRPPATSQATKTDDCSAMGNHCSHMGGPQDFEKSPR 384
           A L R + L  +  LLC+R                           SH+    D   + +
Sbjct: 349 APLVRKIFLHTLPKLLCMR---------------------------SHV----DRYFTQK 377

Query: 385 DRCSPPPPPREASLAVCGLLQELSSIRQFLEKRDEIREVARDWLRVGSVLDKLLFHIYLL 444
           +       P+ +   +   L  +  I + + K +++REV  DW  +  VLD++    +L 
Sbjct: 378 EETESGSGPKSSRNTLEAALDSIRYITRHIMKENDVREVVEDWKFIAQVLDRMFLWTFLF 437

Query: 445 AVLAYSITL 453
             +  S+ L
Sbjct: 438 VSIVGSLGL 446


>gi|4502827 cholinergic receptor, nicotinic, alpha 4 subunit
           precursor [Homo sapiens]
          Length = 627

 Score =  211 bits (537), Expect = 1e-54
 Identities = 109/343 (31%), Positives = 193/343 (56%), Gaps = 6/343 (1%)

Query: 6   LQARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVL 65
           L+A     T   A  RL   L + Y K  RPV +      V   + +  +++VDEKNQ++
Sbjct: 24  LRASSHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMM 83

Query: 66  TTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS-PNIPYVYI 124
           TT +W +Q W D  L+W+P D++N+T + IP++ IW PDI++    D   +  ++   ++
Sbjct: 84  TTNVWVKQEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNADGDFAVTHLTKAHL 143

Query: 125 RHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSD 184
            H G VQ   P    ++CS+D+  FPFD QNC++ F SW  T     I L  +  +V  D
Sbjct: 144 FHDGRVQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSW--TYDKAKIDLVNMHSRV--D 199

Query: 185 RSVFMNQGEWELLGVLPYFREFSMES-SNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMV 243
           +  F   GEW ++  +  +     E  +  Y ++ +  VIRR PLFY ++L++P + +  
Sbjct: 200 QLDFWESGEWVIVDAVGTYNTRKYECCAEIYPDITYAFVIRRLPLFYTINLIIPCLLISC 259

Query: 244 MDIVGFYLPPNSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVI 303
           + ++ FYLP   GE+++  I++LL  +VFL+++++ +P+T++  PLIG Y +  M  + +
Sbjct: 260 LTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTL 319

Query: 304 SLAETIFIVRLVHKQDLQQPVPAWLRHLVLERIAWLLCLREQS 346
           S+  T+F++ + H+      +P W+R + L+ +  LL ++  S
Sbjct: 320 SIVITVFVLNVHHRSPRTHTMPTWVRRVFLDIVPRLLLMKRPS 362



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 16/66 (24%), Positives = 31/66 (46%)

Query: 390 PPPPREASLAVCGLLQELSSIRQFLEKRDEIREVARDWLRVGSVLDKLLFHIYLLAVLAY 449
           PPP    S A+   ++ +  I   L+  D    V  DW  V  V+D++   ++++  L  
Sbjct: 554 PPPHLPLSPALTRAVEGVQYIADHLKAEDTDFSVKEDWKYVAMVIDRIFLWMFIIVCLLG 613

Query: 450 SITLVM 455
           ++ L +
Sbjct: 614 TVGLFL 619


>gi|4502831 cholinergic receptor, nicotinic, alpha 7 precursor [Homo
           sapiens]
          Length = 502

 Score =  207 bits (526), Expect = 2e-53
 Identities = 134/471 (28%), Positives = 224/471 (47%), Gaps = 46/471 (9%)

Query: 21  RLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFL 80
           +L   L+ NY    RPV +  +P TV   + +  I++VDEKNQVLTT IW +  WTD +L
Sbjct: 28  KLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYL 87

Query: 81  QWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNI-PYVYIRHQGEVQNYKPLQVV 139
           QWN  ++  +  +  P   IW PDIL+    D          V +   G  Q   P    
Sbjct: 88  QWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLPPGIFK 147

Query: 140 TACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGV 199
           ++C +D+  FPFDVQ+C L F SW +    +++ +       ++D S ++  GEW+L+G+
Sbjct: 148 SSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQ------EADISGYIPNGEWDLVGI 201

Query: 200 LPYFREFSMESSNY-YAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNSGER 258
                E   E     Y ++ F V +RRR L+Y ++LL+P + +  + ++ F LP +SGE+
Sbjct: 202 PGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEK 261

Query: 259 VSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQ 318
           +S  IT+LL  +VF+++V++ +PAT+   PLI  YF   M ++ +S+  T+ +++  H  
Sbjct: 262 ISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHD 321

Query: 319 DLQQPVPAWLRHLVLERIAWLLCLREQSTSQRPPATSQATKTDDCSAM------------ 366
                +P W R ++L   AW L ++     +  PA     +    +++            
Sbjct: 322 PDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRRCSLASVEMSAVAPPPASN 381

Query: 367 ------------GNHCSHMGGPQDFEKSPRDRCSPP----------PPPREASLAVCGLL 404
                       G HC  +  P       R  CSP           PP  +  LA   +L
Sbjct: 382 GNLLYIGFRGLDGVHC--VPTPDSGVVCGRMACSPTHDEHLLHGGQPPEGDPDLAK--IL 437

Query: 405 QELSSIRQFLEKRDEIREVARDWLRVGSVLDKLLFHIYLLAVLAYSITLVM 455
           +E+  I      +DE   V  +W     V+D+L    + +  +  +I ++M
Sbjct: 438 EEVRYIANRFRCQDESEAVCSEWKFAACVVDRLCLMAFSVFTIICTIGILM 488


>gi|153792669 cholinergic receptor, nicotinic, alpha polypeptide 2
           (neuronal) [Homo sapiens]
          Length = 529

 Score =  204 bits (520), Expect = 1e-52
 Identities = 104/326 (31%), Positives = 184/326 (56%), Gaps = 7/326 (2%)

Query: 21  RLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFL 80
           RL  +L   Y +  RPV +      V   + +  +++VDEKNQ++TT +W +Q W+D  L
Sbjct: 61  RLFKHLFRGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKL 120

Query: 81  QWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKS-PNIPYVYIRHQGEVQNYKPLQVV 139
           +WNP DF NIT L +P++ IW+PDI++    D   +  ++   ++   G V    P    
Sbjct: 121 RWNPTDFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYK 180

Query: 140 TACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGV 199
           ++CS+D+  FPFD QNC + F SW  T     I L ++ + V  D   +   GEW ++  
Sbjct: 181 SSCSIDVTFFPFDQQNCKMKFGSW--TYDKAKIDLEQMEQTV--DLKDYWESGEWAIVNA 236

Query: 200 LPYFREFSMES-SNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNSGER 258
              +     +  +  Y ++ +  VIRR PLFY ++L++P + +  + ++ FYLP + GE+
Sbjct: 237 TGTYNSKKYDCCAEIYPDVTYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSDCGEK 296

Query: 259 VSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQ 318
           ++  I++LL  +VFL+++++ +P+T++  PLIG Y +  M  + +S+  T+F++ + H+ 
Sbjct: 297 ITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHHRS 356

Query: 319 DLQQPVPAWLRHLVLERI-AWLLCLR 343
                +P W+R  +L  +  WLL  R
Sbjct: 357 PSTHTMPHWVRGALLGCVPRWLLMNR 382


>gi|4502837 cholinergic receptor, nicotinic, beta 4 [Homo sapiens]
          Length = 498

 Score =  204 bits (518), Expect = 2e-52
 Identities = 130/476 (27%), Positives = 234/476 (49%), Gaps = 32/476 (6%)

Query: 5   FLQARRSRNTTRPALL--RLSDYLL--TNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDE 60
           FL A   R   R A    +L D LL  T Y   +RP     +  ++ + + +  +++V+E
Sbjct: 11  FLVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNE 70

Query: 61  KNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNI- 119
           + Q++TT +W +Q WTD  L WN   ++ +  L IP   IW+PDI++    D     ++ 
Sbjct: 71  REQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVY 130

Query: 120 PYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPE 179
             + +R  G V    P    +AC +++  FPFD QNC+L F SW +   +I++ L   P 
Sbjct: 131 TNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMT-PT 189

Query: 180 KVKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSI 239
               D   F   GEW+++  LP  R  + +  +Y  ++ +  +I+R+PLFY ++L++P +
Sbjct: 190 ASMDD---FTPSGEWDIVA-LPGRRTVNPQDPSY-VDVTYDFIIKRKPLFYTINLIIPCV 244

Query: 240 FLMVMDIVGFYLPPNSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMA 299
              ++ I+ FYLP + GE+++  I++LL  + FL+++S  +P T++  PLIG Y +  M 
Sbjct: 245 LTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLMFTMV 304

Query: 300 LLVISLAETIFIVRLVHKQDLQQPVPAWLRHLVLERIAWLLCLREQSTSQR-----PPAT 354
           L+  S+  ++ ++ + H+      +  W++   L ++   L ++            PP+ 
Sbjct: 305 LVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAFPPSK 364

Query: 355 S-------QATKTDDCSAMGNHCSHMGGPQDFEKSPRDRCSPPPPPREASLAVCG----- 402
           S        AT T   +  GN    +       KSP    +P   PR+  L   G     
Sbjct: 365 SCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAG-STPVAIPRDFWLRSSGRFRQD 423

Query: 403 ---LLQELSSIRQFLEKRDEIREVARDWLRVGSVLDKLLFHIYLLAVLAYSITLVM 455
               L+ +S I Q ++  DE + V  DW  V  V+D+L   +++   +  ++ L +
Sbjct: 424 VQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFL 479


>gi|4557457 nicotinic cholinergic receptor alpha 1 isoform b
           precursor [Homo sapiens]
          Length = 457

 Score =  201 bits (511), Expect = 1e-51
 Identities = 119/437 (27%), Positives = 221/437 (50%), Gaps = 33/437 (7%)

Query: 21  RLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFL 80
           RL   L  +Y   VRPV D R+   V++ + +  ++NVDE NQ++TT +  +Q W D  L
Sbjct: 26  RLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNL 85

Query: 81  QWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPY--VYIRHQGEVQNYKPLQV 138
           +WNP+D+  + K+ IP++ IW PD+++    D G    + +  V +++ G +    P   
Sbjct: 86  KWNPDDYGGVKKIHIPSEKIWRPDLVLYNNAD-GDFAIVKFTKVLLQYTGHITWTPPAIF 144

Query: 139 VTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLG 198
            + C + + +FPFD QNCS+   +W +    + I+    PE  + D S FM  GEW +  
Sbjct: 145 KSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAIN----PESDQPDLSNFMESGEWVIKE 200

Query: 199 VLPYFRE--FSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNSG 256
              +     +S      Y ++ ++ V++R PL+++V++++P +    +  + FYLP +SG
Sbjct: 201 SRGWKHSVTYSCCPDTPYLDITYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYLPTDSG 260

Query: 257 ERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVH 316
           E+++  I++LL  +VFL+++ + +P+T+   PLIG Y +  M  ++ S+  T+ ++   H
Sbjct: 261 EKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVINTHH 320

Query: 317 KQDLQQPVPAWLRHLVLERIAWLLCLREQSTSQRPPATSQATK--TDDCSAMGNHCSHMG 374
           +      +P W+R + ++ I  ++     ST +RP    Q  K  T+D            
Sbjct: 321 RSPSTHVMPNWVRKVFIDTIPNIMFF---STMKRPSREKQDKKIFTEDIDI--------- 368

Query: 375 GPQDFEKSPRDRCSPPPPPREASL----AVCGLLQELSSIRQFLEKRDEIREVARDWLRV 430
              D    P     PPP    + L     V   ++ +  I + ++   E    A +W  V
Sbjct: 369 --SDISGKP----GPPPMGFHSPLIKHPEVKSAIEGIKYIAETMKSDQESNNAAAEWKYV 422

Query: 431 GSVLDKLLFHIYLLAVL 447
             V+D +L  +++L  +
Sbjct: 423 AMVMDHILLGVFMLVCI 439


>gi|19923122 cholinergic receptor, nicotinic, alpha 3 [Homo sapiens]
          Length = 505

 Score =  198 bits (504), Expect = 8e-51
 Identities = 114/456 (25%), Positives = 223/456 (48%), Gaps = 33/456 (7%)

Query: 21  RLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFL 80
           RL + L  +Y + +RPV +   P  +  +V +  ++ VDE NQ++ T +W +Q W D  L
Sbjct: 37  RLFERLFEDYNEIIRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKL 96

Query: 81  QWNPEDFDNITKLSIPTDSIWVPDILI-NEFVDVGKSPNIPYVYIRHQGEVQNYKPLQVV 139
           +WNP D+     + +P   IW PDI++ N  V   +  +     +++ GEV    P    
Sbjct: 97  KWNPSDYGGAEFMRVPAQKIWKPDIVLYNNAVGDFQVDDKTKALLKYTGEVTWIPPAIFK 156

Query: 140 TACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGV 199
           ++C +D+  FPFD QNC++ F SW +    I++ L      +K     +   GEW ++  
Sbjct: 157 SSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSMNLKD----YWESGEWAIIKA 212

Query: 200 LPYFREFSMES-SNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNSGER 258
             Y  +         Y ++ + + IRR PLFY ++L++P + +  + ++ FYLP + GE+
Sbjct: 213 PGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEK 272

Query: 259 VSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQ 318
           V+  I++LL  +VFL+++++T+P+T++  PLIG Y +  M  + +S+  T+F++ + ++ 
Sbjct: 273 VTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRT 332

Query: 319 DLQQPVPAWLRHLVLERIAWLLCL----REQSTSQRP-PATSQATKTDDC---------- 363
                +P+W++ + L  +  ++ +      +  +Q+P P         +C          
Sbjct: 333 PTTHTMPSWVKTVFLNLLPRVMFMTRPTSNEGNAQKPRPLYGAELSNLNCFSRAESKGCK 392

Query: 364 ------SAMGNHCSHMG-GPQDFEKSPRDRCSPPPPPREASLAVCG-----LLQELSSIR 411
                   M  +C H      +F  +     S        SL+         +Q +  I 
Sbjct: 393 EGYPCQDGMCGYCHHRRIKISNFSANLTRSSSSESVDAVLSLSALSPEIKEAIQSVKYIA 452

Query: 412 QFLEKRDEIREVARDWLRVGSVLDKLLFHIYLLAVL 447
           + ++ ++E +E+  DW  V  V+D++   ++ L  +
Sbjct: 453 ENMKAQNEAKEIQDDWKYVAMVIDRIFLWVFTLVCI 488


>gi|87567783 nicotinic cholinergic receptor alpha 1 isoform a
           precursor [Homo sapiens]
          Length = 482

 Score =  187 bits (475), Expect = 2e-47
 Identities = 119/462 (25%), Positives = 221/462 (47%), Gaps = 58/462 (12%)

Query: 21  RLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQ------- 73
           RL   L  +Y   VRPV D R+   V++ + +  ++NVDE NQ++TT +  +Q       
Sbjct: 26  RLVAKLFKDYSSVVRPVEDHRQVVEVTVGLQLIQLINVDEVNQIVTTNVRLKQGDMVDLP 85

Query: 74  ------------------YWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGK 115
                              W D  L+WNP+D+  + K+ IP++ IW PD+++    D G 
Sbjct: 86  RPSCVTLGVPLFSHLQNEQWVDYNLKWNPDDYGGVKKIHIPSEKIWRPDLVLYNNAD-GD 144

Query: 116 SPNIPY--VYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINIS 173
              + +  V +++ G +    P    + C + + +FPFD QNCS+   +W +    + I+
Sbjct: 145 FAIVKFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQNCSMKLGTWTYDGSVVAIN 204

Query: 174 LWRLPEKVKSDRSVFMNQGEWELLGVLPYFRE--FSMESSNYYAEMKFYVVIRRRPLFYV 231
               PE  + D S FM  GEW +     +     +S      Y ++ ++ V++R PL+++
Sbjct: 205 ----PESDQPDLSNFMESGEWVIKESRGWKHSVTYSCCPDTPYLDITYHFVMQRLPLYFI 260

Query: 232 VSLLLPSIFLMVMDIVGFYLPPNSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIG 291
           V++++P +    +  + FYLP +SGE+++  I++LL  +VFL+++ + +P+T+   PLIG
Sbjct: 261 VNVIIPCLLFSFLTGLVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIG 320

Query: 292 VYFVVCMALLVISLAETIFIVRLVHKQDLQQPVPAWLRHLVLERIAWLLCLREQSTSQRP 351
            Y +  M  ++ S+  T+ ++   H+      +P W+R + ++ I  ++     ST +RP
Sbjct: 321 KYMLFTMVFVIASIIITVIVINTHHRSPSTHVMPNWVRKVFIDTIPNIMFF---STMKRP 377

Query: 352 PATSQATK--TDDCSAMGNHCSHMGGPQDFEKSPRDRCSPPPPPREASL----AVCGLLQ 405
               Q  K  T+D               D    P     PPP    + L     V   ++
Sbjct: 378 SREKQDKKIFTEDIDI-----------SDISGKP----GPPPMGFHSPLIKHPEVKSAIE 422

Query: 406 ELSSIRQFLEKRDEIREVARDWLRVGSVLDKLLFHIYLLAVL 447
            +  I + ++   E    A +W  V  V+D +L  +++L  +
Sbjct: 423 GIKYIAETMKSDQESNNAAAEWKYVAMVMDHILLGVFMLVCI 464


>gi|41327726 nicotinic acetylcholine receptor beta 1 subunit
           precursor [Homo sapiens]
          Length = 501

 Score =  186 bits (473), Expect = 3e-47
 Identities = 115/454 (25%), Positives = 221/454 (48%), Gaps = 35/454 (7%)

Query: 21  RLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFL 80
           RL + L + Y   VRP R+      VS+ +I+  +++++EK++ ++T ++    WTD  L
Sbjct: 29  RLREKLFSGYDSSVRPAREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLEWTDYRL 88

Query: 81  QWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPY-VYIRHQGEVQNYKPLQVV 139
            W+P + D I  L I  +S+W+PD+++    D      +   V +   G V+   P    
Sbjct: 89  SWDPAEHDGIDSLRITAESVWLPDVVLLNNNDGNFDVALDISVVVSSDGSVRWQPPGIYR 148

Query: 140 TACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPE-----KVKSDRSVFMNQGEW 194
           ++CS+ +  FPFD QNC++ F+S+ +   ++++     P+     ++      F+  G+W
Sbjct: 149 SSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLQTGLGPDGQGHQEIHIHEGTFIENGQW 208

Query: 195 ELLGVLPYFREFSMES----SNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFY 250
           E++       +   +          E+ FY++IRR+PLFY+V+++ P I + ++ I  FY
Sbjct: 209 EIIHKPSRLIQPPGDPRGGREGQRQEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFY 268

Query: 251 LPPNSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIF 310
           LPP++GE++   I  LL  +VFL++++D +P T++  P+I  Y +  M L+  S+  ++ 
Sbjct: 269 LPPDAGEKMGLSIFALLTLTVFLLLLADKVPETSLSVPIIIKYLMFTMVLVTFSVILSVV 328

Query: 311 IVRLVHKQDLQQPVPAWLRHLVLERIAWLLCLREQSTSQRPPATSQATKTDDCSAMGNHC 370
           ++ L H+      +P W+R + + ++   L L+        P      +   CS+ G+  
Sbjct: 329 VLNLHHRSPHTHQMPLWVRQIFIHKLPLYLRLKRPK-----PERDLMPEPPHCSSPGSGW 383

Query: 371 SHMGGPQDFEKSPRDRCSPPPPPREASLA-------------VCGLLQEL-------SSI 410
                     K P D   P P   +  L+                LL EL       S I
Sbjct: 384 GRGTDEYFIRKPPSDFLFPKPNRFQPELSAPDLRRFIDGPNRAVALLPELREVVSSISYI 443

Query: 411 RQFLEKRDEIREVARDWLRVGSVLDKLLFHIYLL 444
            + L+++++   +  DW  V  V+D+L    +++
Sbjct: 444 ARQLQEQEDHDALKEDWQFVAMVVDRLFLWTFII 477


>gi|4557461 nicotinic acetylcholine receptor delta polypeptide
           precursor [Homo sapiens]
          Length = 517

 Score =  176 bits (446), Expect = 4e-44
 Identities = 104/328 (31%), Positives = 179/328 (54%), Gaps = 23/328 (7%)

Query: 30  YRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDN 89
           Y K +RPV    +   V++ + +  ++++ E  + LTT +W    WTD  L+WN E+F N
Sbjct: 38  YNKELRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEFGN 97

Query: 90  ITKLSIPTDSIWVPDILINEFVDVGKSPNIPY---VYIRHQGEVQNYKPLQVVTACSLDI 146
           I+ L +P D +W+P+I++    D   S  I Y   V + H G V    P    ++C + +
Sbjct: 98  ISVLRLPPDMVWLPEIVLENNND--GSFQISYSCNVLVYHYGFVYWLPPAIFRSSCPISV 155

Query: 147 YNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKS--------DRSVFMNQGEWELL- 197
             FPFD QNCSL F+S  +T ++I +SL +  ++ ++        D   F   GEWE++ 
Sbjct: 156 TYFPFDWQNCSLKFSSLKYTAKEITLSLKQDAKENRTYPVEWIIIDPEGFTENGEWEIVH 215

Query: 198 -----GVLPYFREFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLP 252
                 V P     +   S    ++ FY++IRR+PLFY++++L+P + +  M  + FYLP
Sbjct: 216 RPARVNVDPR----APLDSPSRQDITFYLIIRRKPLFYIINILVPCVLISFMVNLVFYLP 271

Query: 253 PNSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIV 312
            +SGE+ S  I++LL  SVFL+++S  LPAT++  PLIG + +  M L+ + +   + ++
Sbjct: 272 ADSGEKTSVAISVLLAQSVFLLLISKRLPATSMAIPLIGKFLLFGMVLVTMVVVICVIVL 331

Query: 313 RLVHKQDLQQPVPAWLRHLVLERIAWLL 340
            +  +      +   ++ L LE +  LL
Sbjct: 332 NIHFRTPSTHVLSEGVKKLFLETLPELL 359


>gi|4557463 nicotinic acetylcholine receptor epsilon polypeptide
           precursor [Homo sapiens]
          Length = 493

 Score =  164 bits (415), Expect = 2e-40
 Identities = 106/447 (23%), Positives = 208/447 (46%), Gaps = 39/447 (8%)

Query: 20  LRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEF 79
           LRL  +L  NY  G RPVR+     T+S+ V +  +++++EK + LTT +W    W D  
Sbjct: 25  LRLYHHLFNNYDPGSRPVREPEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYR 84

Query: 80  LQWNPEDFDNITKLSIPTDSIWVPDILINEFVD----VGKSPNIPYVYIRHQGEVQNYKP 135
           L ++ +DF  I  L +P++ +W+P+I++   +D    V    N   V +   G V    P
Sbjct: 85  LNYSKDDFGGIETLRVPSELVWLPEIVLENNIDGQFGVAYDAN---VLVYEGGSVTWLPP 141

Query: 136 LQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISL-----WRLPEKVKSDRSVFMN 190
               + C++++  FPFD QNCSL F S  +  +++  +       +   K+  D   +  
Sbjct: 142 AIYRSVCAVEVTYFPFDWQNCSLIFRSQTYNAEEVEFTFAVDNDGKTINKIDIDTEAYTE 201

Query: 191 QGEWEL---LGVLPYFREFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIV 247
            GEW +    GV+      + +      ++ + ++IRR+PLFYV+++++P + +  + ++
Sbjct: 202 NGEWAIDFCPGVIRRHHGGATDGPG-ETDVIYSLIIRRKPLFYVINIIVPCVLISGLVLL 260

Query: 248 GFYLPPNS-GERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLA 306
            ++LP  + G++ +  I +LL  +VFL +++  +P T++  PL+G + +  M +  + + 
Sbjct: 261 AYFLPAQAGGQKCTVSINVLLAQTVFLFLIAQKIPETSLSVPLLGRFLIFVMVVATLIVM 320

Query: 307 ETIFIVRLVHKQDLQQPVPAWLRHLVLERIAWLLCLREQSTSQRPPATSQATKTDDCSAM 366
             + ++ +  +      +   LRH++LE +  LL      +   P A   A+     S++
Sbjct: 321 NCVIVLNVSQRTPTTHAMSPRLRHVLLELLPRLL-----GSPPPPEAPRAASPPRRASSV 375

Query: 367 GNHCSHMGGPQDFEKSPRDRCSPPPPPREASLAVCGLLQELSS--------------IRQ 412
           G     +   +   K PR                    Q L +              + +
Sbjct: 376 G---LLLRAEELILKKPRSELVFEGQRHRQGTWTAAFCQSLGAAAPEVRCCVDAVNFVAE 432

Query: 413 FLEKRDEIREVARDWLRVGSVLDKLLF 439
               ++   E   DW+R+G+ LD + F
Sbjct: 433 STRDQEATGEEVSDWVRMGNALDNICF 459


>gi|223468705 5-hydroxytryptamine receptor 3 subunit D isoform 1
           [Homo sapiens]
          Length = 404

 Score =  144 bits (363), Expect = 2e-34
 Identities = 128/450 (28%), Positives = 200/450 (44%), Gaps = 78/450 (17%)

Query: 38  RDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPT 97
           R W       +  I++ +L  D   Q++T+++W           WNP++   I K  + T
Sbjct: 3   RGWFHGKGFLLGFILHLLLQ-DSHLQLVTSFLWLNM--------WNPDECGGIKKSGMAT 53

Query: 98  DSIWVPDILINEFVDVGKSPNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCS 157
           +++W+ D+ I E VD              Q        + +V A S  I    +   + S
Sbjct: 54  ENLWLSDVFIEESVD--------------QTPAGLMASMSIVKATSNTISQCGW---SAS 96

Query: 158 LTFTSWLHTIQDIN------------ISLWRLPEKVKS--DRSVFMNQGEWELLGVLPYF 203
             +T  +    D                 WR   +      R+ F  + EW LLG+    
Sbjct: 97  ANWTPSISPSMDRGERSPSALSPTQVTRAWRRMSRSFQIHHRTSFRTRREWVLLGIQKRT 156

Query: 204 REFSMESSNYYAEMKFYVVIRRR--PLFYVVSLLLPSIFLMVMDIVGFYLPPNSGERVSF 261
            + ++ ++N Y +  F+V IRRR  P  YVV+ L+PS  L+ +D + FYLP  SG    F
Sbjct: 157 IKVTV-ATNQYEQAIFHVAIRRRCRPSPYVVNFLVPSGILIAIDALSFYLPLESGNCAPF 215

Query: 262 KITLLLGYSVFLIIVSDTLPATAIGTPLI------------GVYFVVCMALLVISLAETI 309
           K+T+LLGYSVFL++++D LPAT+  +               GVYF +C++L+V SL ETI
Sbjct: 216 KMTVLLGYSVFLLMMNDLLPATSTSSHASLVRPHPSRDQKRGVYFALCLSLMVGSLLETI 275

Query: 310 FIVRLVHKQDLQQ-PVPAWLRHLVLERIAWLLCLREQSTSQRPPATSQATKTDDCSAMGN 368
           FI  L+H    Q  P+P WL  L+L       C         P A  +  K       G 
Sbjct: 276 FITHLLHVATTQPLPLPRWLHSLLLHCTGQGRCC--------PTAPQKGNK-----GPGL 322

Query: 369 HCSHMGGPQDFEKSPRDRCSPPPPPREASLAVCGLLQELSSIRQFLEKRDEIREVARDWL 428
             +H+ G     K P       P P EA L   G  +   + R+   ++    E+   W+
Sbjct: 323 TPTHLPG----VKEPEVSAGQMPGPGEAELT--GGSEWTRAQREHEAQKQHSVEL---WV 373

Query: 429 RVGSVLDKLLFHIYLLAVLAYSITLVMLWS 458
           +    +D LLF +YLL + +  IT++ LW+
Sbjct: 374 QFSHAMDALLFRLYLLFMASSIITVICLWN 403


>gi|61743914 cholinergic receptor, nicotinic, gamma polypeptide
           precursor [Homo sapiens]
          Length = 517

 Score =  144 bits (362), Expect = 2e-34
 Identities = 89/348 (25%), Positives = 172/348 (49%), Gaps = 11/348 (3%)

Query: 21  RLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFL 80
           RL   L+ NY   +RP         VS+ + +  +++++E+ + LTT +W    W D  L
Sbjct: 28  RLLADLMQNYDPNLRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRL 87

Query: 81  QWNPEDFDNITKLSIPTDSIWVPDILINEFVD-VGKSPNIPYVYIRHQGEVQNYKPLQVV 139
           +W+P D++ +  L +P+  +W PDI++   VD V +      V +   G +    P    
Sbjct: 88  RWDPRDYEGLWVLRVPSTMVWRPDIVLENNVDGVFEVALYCNVLVSPDGCIYWLPPAIFR 147

Query: 140 TACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISL----WRLPEKVKSDRSVFMNQGEWE 195
           +ACS+ +  FPFD QNCSL F S  ++  +I++ L     +  E +  D   F   GEW 
Sbjct: 148 SACSISVTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQEDGQTIEWIFIDPEAFTENGEWA 207

Query: 196 L--LGVLPYFREFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPP 253
           +            +      + ++ FY++I+R+PLFYV++++ P + +  + I+  +LP 
Sbjct: 208 IQHRPAKMLLDPAAPAQEAGHQKVVFYLLIQRKPLFYVINIIAPCVLISSVAILIHFLPA 267

Query: 254 NS-GERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIV 312
            + G++ +  I +LL  +VFL +V+  +P T+   PLI  Y    + + ++ +   + ++
Sbjct: 268 KAGGQKCTVAINVLLAQTVFLFLVAKKVPETSQAVPLISKYLTFLLVVTILIVVNAVVVL 327

Query: 313 RLVHKQDLQQPVPAWLRHLVLERIAWLLCLREQSTSQRPPATSQATKT 360
            +  +      +   +R + L  +  LL +  +  +   PA  Q T++
Sbjct: 328 NVSLRSPHTHSMARGVRKVFLRLLPQLLRMHVRPLA---PAAVQDTQS 372


>gi|23312388 CHRNA7-FAM7A fusion isoform 1 [Homo sapiens]
          Length = 412

 Score =  139 bits (351), Expect = 4e-33
 Identities = 96/369 (26%), Positives = 171/369 (46%), Gaps = 45/369 (12%)

Query: 122 VYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKV 181
           V +   G  Q   P    ++C +D+  FPFDVQ+C L F SW +    +++ +       
Sbjct: 40  VLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQ------ 93

Query: 182 KSDRSVFMNQGEWELLGVLPYFREFSMESSNY-YAEMKFYVVIRRRPLFYVVSLLLPSIF 240
           ++D S ++  GEW+L+G+     E   E     Y ++ F V +RRR L+Y ++LL+P + 
Sbjct: 94  EADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVL 153

Query: 241 LMVMDIVGFYLPPNSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMAL 300
           +  + ++ F LP +SGE++S  IT+LL  +VF+++V++ +PAT+   PLI  YF   M +
Sbjct: 154 ISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMII 213

Query: 301 LVISLAETIFIVRLVHKQDLQQPVPAWLRHLVLERIAWLLCLREQSTSQRPPATSQATKT 360
           + +S+  T+ +++  H       +P W R ++L   AW L ++     +  PA     + 
Sbjct: 214 VGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRR 273

Query: 361 DDCSAM------------------------GNHCSHMGGPQDFEKSPRDRCSPP------ 390
              +++                        G HC  +  P       R  CSP       
Sbjct: 274 CSLASVEMSAVAPPPASNGNLLYIGFRGLDGVHC--VPTPDSGVVCGRMACSPTHDEHLL 331

Query: 391 ----PPPREASLAVCGLLQELSSIRQFLEKRDEIREVARDWLRVGSVLDKLLFHIYLLAV 446
               PP  +  LA   +L+E+  I      +DE   V  +W     V+D+L    + +  
Sbjct: 332 HGGQPPEGDPDLAK--ILEEVRYIANRFRCQDESEAVCSEWKFAACVVDRLCLMAFSVFT 389

Query: 447 LAYSITLVM 455
           +  +I ++M
Sbjct: 390 IICTIGILM 398


>gi|47519877 5-hydroxytryptamine receptor 3 subunit D isoform 2
           [Homo sapiens]
          Length = 279

 Score =  117 bits (292), Expect = 3e-26
 Identities = 88/253 (34%), Positives = 126/253 (49%), Gaps = 37/253 (14%)

Query: 221 VVIRRR--PLFYVVSLLLPSIFLMVMDIVGFYLPPNSGERVSFKITLLLGYSVFLIIVSD 278
           V IRRR  P  YVV+ L+PS  L+ +D + FYLP  SG    FK+T+LLGYSVFL++++D
Sbjct: 48  VAIRRRCRPSPYVVNFLVPSGILIAIDALSFYLPLESGNCAPFKMTVLLGYSVFLLMMND 107

Query: 279 TLPATAIGTPLI------------GVYFVVCMALLVISLAETIFIVRLVHKQDLQQ-PVP 325
            LPAT+  +               GVYF +C++L+V SL ETIFI  L+H    Q  P+P
Sbjct: 108 LLPATSTSSHASLVRPHPSRDQKRGVYFALCLSLMVGSLLETIFITHLLHVATTQPLPLP 167

Query: 326 AWLRHLVLERIAWLLCLREQSTSQRPPATSQATKTDDCSAMGNHCSHMGGPQDFEKSPRD 385
            WL  L+L       C         P A  +  K       G   +H+ G     K P  
Sbjct: 168 RWLHSLLLHCTGQGRCC--------PTAPQKGNK-----GPGLTPTHLPG----VKEPEV 210

Query: 386 RCSPPPPPREASLAVCGLLQELSSIRQFLEKRDEIREVARDWLRVGSVLDKLLFHIYLLA 445
                P P EA L   G  +   + R+   ++    E+   W++    +D LLF +YLL 
Sbjct: 211 SAGQMPGPGEAELT--GGSEWTRAQREHEAQKQHSVEL---WVQFSHAMDALLFRLYLLF 265

Query: 446 VLAYSITLVMLWS 458
           + +  IT++ LW+
Sbjct: 266 MASSIITVICLWN 278


>gi|23312390 CHRNA7-FAM7A fusion isoform 2 [Homo sapiens]
          Length = 321

 Score =  113 bits (283), Expect = 3e-25
 Identities = 79/309 (25%), Positives = 143/309 (46%), Gaps = 39/309 (12%)

Query: 182 KSDRSVFMNQGEWELLGVLPYFREFSMESSNY-YAEMKFYVVIRRRPLFYVVSLLLPSIF 240
           ++D S ++  GEW+L+G+     E   E     Y ++ F V +RRR L+Y ++LL+P + 
Sbjct: 3   EADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVL 62

Query: 241 LMVMDIVGFYLPPNSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMAL 300
           +  + ++ F LP +SGE++S  IT+LL  +VF+++V++ +PAT+   PLI  YF   M +
Sbjct: 63  ISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMII 122

Query: 301 LVISLAETIFIVRLVHKQDLQQPVPAWLRHLVLERIAWLLCLREQSTSQRPPATSQATKT 360
           + +S+  T+ +++  H       +P W R ++L   AW L ++     +  PA     + 
Sbjct: 123 VGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHKQRR 182

Query: 361 DDCSAM------------------------GNHCSHMGGPQDFEKSPRDRCSPP------ 390
              +++                        G HC  +  P       R  CSP       
Sbjct: 183 CSLASVEMSAVAPPPASNGNLLYIGFRGLDGVHC--VPTPDSGVVCGRMACSPTHDEHLL 240

Query: 391 ----PPPREASLAVCGLLQELSSIRQFLEKRDEIREVARDWLRVGSVLDKLLFHIYLLAV 446
               PP  +  LA   +L+E+  I      +DE   V  +W     V+D+L    + +  
Sbjct: 241 HGGQPPEGDPDLAK--ILEEVRYIANRFRCQDESEAVCSEWKFAACVVDRLCLMAFSVFT 298

Query: 447 LAYSITLVM 455
           +  +I ++M
Sbjct: 299 IICTIGILM 307


>gi|206725456 zinc activated ligand-gated ion channel [Homo sapiens]
          Length = 412

 Score =  105 bits (261), Expect = 1e-22
 Identities = 70/278 (25%), Positives = 127/278 (45%), Gaps = 13/278 (4%)

Query: 43  PTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWV 102
           P  V + V V  + NVD     +++ +  R  W D  L WN         +++P +S+W 
Sbjct: 59  PLLVDVRVFVSNVFNVDILRYTMSSMLLLRLSWLDTRLAWNTSAHPRHA-ITLPWESLWT 117

Query: 103 PDILINEFVDVGKSPNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTS 162
           P + I E + V      P   +   G V+    L   T C+ ++ +FP D  NCSL+F +
Sbjct: 118 PRLTILEALWVDWRDQSPQARVDQDGHVKLNLALATETNCNFELLHFPRDHSNCSLSFYA 177

Query: 163 WLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEMKFYVV 222
             +T  ++      + E V   R   +            Y  +  +         +  + 
Sbjct: 178 LSNTAMELEFQAHVVNEIVSVKREYVV------------YDLKTQVPPQQLVPCFQVTLR 225

Query: 223 IRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNSGERVSFKITLLLGYSVFLIIVSDTLPA 282
           ++   L  +++LL+P+  L++ D+ G  LP  + ER+ +K+TLLL Y V    +   LP+
Sbjct: 226 LKNTALKSIIALLVPAEALLLADVCGGLLPLRAIERIGYKVTLLLSYLVLHSSLVQALPS 285

Query: 283 TAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQDL 320
           ++   PL+  YF + + LL +S  ET+ +  L+ + +L
Sbjct: 286 SSSCNPLLIYYFTILLLLLFLSTIETVLLAGLLARGNL 323


>gi|157743288 gamma-aminobutyric acid (GABA) receptor, rho 3 [Homo
           sapiens]
          Length = 467

 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 73/285 (25%), Positives = 124/285 (43%), Gaps = 9/285 (3%)

Query: 43  PTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWV 102
           P  V IDV V +I ++ E N   T   + R YW DE L +      ++T     T  IWV
Sbjct: 82  PVPVGIDVHVESIDSISETNMDFTMTFYLRHYWKDERLSFPSTANKSMTFDHRLTRKIWV 141

Query: 103 PDILI----NEFVDVGKSPNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSL 158
           PDI        F+      NI  + +   G V     + V   C +D   FP D QNCSL
Sbjct: 142 PDIFFVHSKRSFIHDTTMENI-MLRVHPDGNVLLSLRITVSAMCFMDFSRFPLDTQNCSL 200

Query: 159 TFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEMK 218
              S+ +   D+ +      + + ++  + ++Q   E          +S  S+ +Y  + 
Sbjct: 201 ELESYAYNEDDLMLYWKHGNKSLNTEEHMSLSQFFIEDFSASSGLAFYS--STGWYNRLF 258

Query: 219 FYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNS-GERVSFKITLLLGYSVFLIIVS 277
              V+RR   F+V+    P+I ++++  V F++   +   RVS  IT +L  S  +  VS
Sbjct: 259 INFVLRRHVFFFVLQTYFPAILMVMLSWVSFWIDRRAVPARVSLGITTVLTMSTIITAVS 318

Query: 278 DTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQDLQQ 322
            ++P  +     + VY  V    + +S+ E   +  L   ++ +Q
Sbjct: 319 ASMPQVSY-LKAVDVYLWVSSLFVFLSVIEYAAVNYLTTVEERKQ 362


>gi|7657106 gamma-aminobutyric acid (GABA) A receptor, pi [Homo
           sapiens]
          Length = 440

 Score = 85.9 bits (211), Expect = 7e-17
 Identities = 75/305 (24%), Positives = 130/305 (42%), Gaps = 22/305 (7%)

Query: 26  LLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPE 85
           L   Y K +RP     +P  +++ + + +I ++ E N   T  I+ RQ W D+ L +  E
Sbjct: 44  LTAGYNKFLRP-NFGGEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRLVF--E 100

Query: 86  DFDNITKLSIPTDSIWVPDILINEF-------VDVGKSPNIPYVYIRHQGEVQNYKPLQV 138
              + T  +   + +WVPD  I E        V VG       + +   G V     +  
Sbjct: 101 GNKSFTLDARLVEFLWVPDTYIVESKKSFLHEVTVGNR----LIRLFSNGTVLYALRITT 156

Query: 139 VTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLG 198
             AC++D+  +P D Q C L   SW +   D+  +  R  + V+    + + Q   E   
Sbjct: 157 TVACNMDLSKYPMDTQTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYF 216

Query: 199 VLPYFREFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNS-GE 257
            L      S + +  Y  +     +RR  L++++   +PS FL+V+  V F++  +S   
Sbjct: 217 TLV---TRSQQETGNYTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPA 273

Query: 258 RVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHK 317
           R    +T +L  +  +I    +LP T      I VY  +C + +  +L E      + H 
Sbjct: 274 RTCIGVTTVLSMTTLMIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLE----YAVAHY 329

Query: 318 QDLQQ 322
             LQQ
Sbjct: 330 SSLQQ 334


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.139    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,682,420
Number of Sequences: 37866
Number of extensions: 870158
Number of successful extensions: 3899
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 3698
Number of HSP's gapped (non-prelim): 96
length of query: 463
length of database: 18,247,518
effective HSP length: 106
effective length of query: 357
effective length of database: 14,233,722
effective search space: 5081438754
effective search space used: 5081438754
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.