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Search of human proteins with 25092719
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|25092719 purinergic receptor P2X2 isoform A [Homo sapiens]
(471 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|25092719 purinergic receptor P2X2 isoform A [Homo sapiens] 981 0.0
gi|25092733 purinergic receptor P2X2 isoform D [Homo sapiens] 967 0.0
gi|7706629 purinergic receptor P2X2 isoform C [Homo sapiens] 920 0.0
gi|28416923 purinergic receptor P2X2 isoform B [Homo sapiens] 789 0.0
gi|28416921 purinergic receptor P2X2 isoform H [Homo sapiens] 725 0.0
gi|27881423 purinergic receptor P2X2 isoform I [Homo sapiens] 674 0.0
gi|28416927 purinergic receptor P2X4 [Homo sapiens] 345 7e-95
gi|28416925 purinergic receptor P2X3 [Homo sapiens] 336 3e-92
gi|28416933 purinergic receptor P2X5 isoform A [Homo sapiens] 305 6e-83
gi|4505545 purinergic receptor P2X1 [Homo sapiens] 299 4e-81
gi|157419148 purinergic receptor P2X6 isoform 1 [Homo sapiens] 296 2e-80
gi|227116341 purinergic receptor P2X6 isoform 2 [Homo sapiens] 269 5e-72
gi|28416935 purinergic receptor P2X5 isoform B [Homo sapiens] 269 5e-72
gi|29294631 purinergic receptor P2X7 [Homo sapiens] 241 8e-64
gi|28416937 purinergic receptor P2X5 isoform C [Homo sapiens] 148 1e-35
gi|150170670 piccolo isoform 2 [Homo sapiens] 38 0.017
gi|150378539 piccolo isoform 1 [Homo sapiens] 38 0.017
gi|54860079 nadrin isoform 1 [Homo sapiens] 37 0.039
gi|54860105 nadrin isoform 2 [Homo sapiens] 37 0.039
gi|23397666 transcriptional co-repressor Sin3A [Homo sapiens] 37 0.051
gi|223941785 transcriptional co-repressor Sin3A [Homo sapiens] 37 0.051
gi|223941782 transcriptional co-repressor Sin3A [Homo sapiens] 37 0.051
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 36 0.066
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 36 0.086
gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens] 36 0.086
gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens] 36 0.086
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 35 0.11
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 35 0.11
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 35 0.11
gi|39812378 RAN binding protein 9 [Homo sapiens] 35 0.19
>gi|25092719 purinergic receptor P2X2 isoform A [Homo sapiens]
Length = 471
Score = 981 bits (2537), Expect = 0.0
Identities = 471/471 (100%), Positives = 471/471 (100%)
Query: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV
Sbjct: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
Query: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ 120
FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ
Sbjct: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ 120
Query: 121 TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 180
TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED
Sbjct: 121 TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 180
Query: 181 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 240
GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK
Sbjct: 181 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 240
Query: 241 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 300
LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN
Sbjct: 241 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 300
Query: 301 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCD 360
FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCD
Sbjct: 301 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCD 360
Query: 361 WILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSG 420
WILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSG
Sbjct: 361 WILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSG 420
Query: 421 QEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL 471
QEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL
Sbjct: 421 QEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL 471
>gi|25092733 purinergic receptor P2X2 isoform D [Homo sapiens]
Length = 497
Score = 967 bits (2500), Expect = 0.0
Identities = 471/497 (94%), Positives = 471/497 (94%), Gaps = 26/497 (5%)
Query: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV
Sbjct: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
Query: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ 120
FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ
Sbjct: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ 120
Query: 121 TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 180
TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED
Sbjct: 121 TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 180
Query: 181 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 240
GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK
Sbjct: 181 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 240
Query: 241 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 300
LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN
Sbjct: 241 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 300
Query: 301 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGV------ 354
FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGV
Sbjct: 301 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVVRNPLW 360
Query: 355 --------------------GSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVT 394
GSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVT
Sbjct: 361 GPSGCGGSTRPLHTGLCWPQGSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVT 420
Query: 395 LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPAS 454
LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPAS
Sbjct: 421 LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPAS 480
Query: 455 EPAQASTPTDPKGLAQL 471
EPAQASTPTDPKGLAQL
Sbjct: 481 EPAQASTPTDPKGLAQL 497
>gi|7706629 purinergic receptor P2X2 isoform C [Homo sapiens]
Length = 447
Score = 920 bits (2377), Expect = 0.0
Identities = 447/471 (94%), Positives = 447/471 (94%), Gaps = 24/471 (5%)
Query: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV
Sbjct: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
Query: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ 120
FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPE
Sbjct: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPE----------------- 103
Query: 121 TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 180
SIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED
Sbjct: 104 -------SIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 156
Query: 181 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 240
GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK
Sbjct: 157 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 216
Query: 241 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 300
LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN
Sbjct: 217 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 276
Query: 301 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCD 360
FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCD
Sbjct: 277 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCD 336
Query: 361 WILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSG 420
WILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSG
Sbjct: 337 WILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSG 396
Query: 421 QEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL 471
QEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL
Sbjct: 397 QEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL 447
>gi|28416923 purinergic receptor P2X2 isoform B [Homo sapiens]
Length = 404
Score = 789 bits (2037), Expect = 0.0
Identities = 384/400 (96%), Positives = 386/400 (96%), Gaps = 11/400 (2%)
Query: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV
Sbjct: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYV 60
Query: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ 120
FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ
Sbjct: 61 FIVQKSYQESETGPESSIITKVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQ 120
Query: 121 TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 180
TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED
Sbjct: 121 TQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVED 180
Query: 181 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 240
GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK
Sbjct: 181 GASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFK 240
Query: 241 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 300
LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN
Sbjct: 241 LGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYN 300
Query: 301 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCD 360
FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCD
Sbjct: 301 FRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCD 360
Query: 361 WILLTFMNKNKVYSHKKFDKV-----------CTPSHPSG 389
WILLTFMNKNKVYSHKKFDK+ TP+ P G
Sbjct: 361 WILLTFMNKNKVYSHKKFDKMVDTPASEPAQASTPTDPKG 400
Score = 52.8 bits (125), Expect = 7e-07
Identities = 24/26 (92%), Positives = 26/26 (100%)
Query: 446 EQMVDTPASEPAQASTPTDPKGLAQL 471
++MVDTPASEPAQASTPTDPKGLAQL
Sbjct: 379 DKMVDTPASEPAQASTPTDPKGLAQL 404
>gi|28416921 purinergic receptor P2X2 isoform H [Homo sapiens]
Length = 379
Score = 725 bits (1871), Expect = 0.0
Identities = 344/344 (100%), Positives = 344/344 (100%)
Query: 128 SIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQF 187
SIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQF
Sbjct: 36 SIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQF 95
Query: 188 LGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEK 247
LGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEK
Sbjct: 96 LGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEK 155
Query: 248 AGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYY 307
AGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYY
Sbjct: 156 AGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYY 215
Query: 308 KINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFM 367
KINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFM
Sbjct: 216 KINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFM 275
Query: 368 NKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGA 427
NKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGA
Sbjct: 276 NKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGA 335
Query: 428 ECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL 471
ECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL
Sbjct: 336 ECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTPTDPKGLAQL 379
Score = 77.8 bits (190), Expect = 2e-14
Identities = 35/35 (100%), Positives = 35/35 (100%)
Query: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIV 35
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIV
Sbjct: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIV 35
>gi|27881423 purinergic receptor P2X2 isoform I [Homo sapiens]
Length = 399
Score = 674 bits (1739), Expect = 0.0
Identities = 319/319 (100%), Positives = 319/319 (100%)
Query: 153 GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSK 212
GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSK
Sbjct: 81 GLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSK 140
Query: 213 GNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDL 272
GNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDL
Sbjct: 141 GNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDL 200
Query: 273 DLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQ 332
DLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQ
Sbjct: 201 DLPASECNPKYSFRRLDPKHVPASSGYNFRFAKYYKINGTTTRTLIKAYGIRIDVIVHGQ 260
Query: 333 AGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWP 392
AGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWP
Sbjct: 261 AGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWP 320
Query: 393 VTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTP 452
VTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTP
Sbjct: 321 VTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTP 380
Query: 453 ASEPAQASTPTDPKGLAQL 471
ASEPAQASTPTDPKGLAQL
Sbjct: 381 ASEPAQASTPTDPKGLAQL 399
Score = 82.0 bits (201), Expect = 1e-15
Identities = 38/40 (95%), Positives = 38/40 (95%)
Query: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRNRR 40
MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVR R
Sbjct: 1 MAAAQPKYPAGATARRLARGCWSALWDYETPKVIVVRIHR 40
>gi|28416927 purinergic receptor P2X4 [Homo sapiens]
Length = 388
Score = 345 bits (884), Expect = 7e-95
Identities = 185/377 (49%), Positives = 250/377 (66%), Gaps = 19/377 (5%)
Query: 20 GCWSAL----WDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPE 75
GC +AL ++Y+TP+++++R+R++G++ RAVQLLIL Y + +VF+ +K YQE+++
Sbjct: 3 GCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDS-VV 61
Query: 76 SSIITKVKGITTSE-----HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIR 130
SS+ TKVKG+ + ++WDV +YV P + + ++T V T +QTQG CPE I
Sbjct: 62 SSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPE-IP 120
Query: 131 VHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQ--FL 188
C SDA C AG NG+ TGRCV + G KTCEV WCPVED V Q FL
Sbjct: 121 DATTVCKSDASCTAGSAGTHSNGVSTGRCVAF-NGSVKTCEVAAWCPVEDDTHVPQPAFL 179
Query: 189 GTMAPNFTILIKNSIHYPKFHFSKGNIADR-TDGYLKRCTFHEASDLYCPIFKLGFIVEK 247
A NFT+L+KN+I YPKF+FSK NI T YLK C + +D +CPIF+LG IVE
Sbjct: 180 KA-AENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVEN 238
Query: 248 AGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVP--ASSGYNFRFAK 305
AG SF ++A +GG++G+ +NWDC+LD AS C P+YSFRRLD + V S GYNFRFAK
Sbjct: 239 AGHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAK 298
Query: 306 YYK-INGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILL 364
YY+ + G RTLIKAYGIR D+IV G+AGKF +IPT+IN+ + L +G+ + LCD I+L
Sbjct: 299 YYRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVL 358
Query: 365 TFMNKNKVYSHKKFDKV 381
M K Y KK+ V
Sbjct: 359 YCMKKRLYYREKKYKYV 375
>gi|28416925 purinergic receptor P2X3 [Homo sapiens]
Length = 397
Score = 336 bits (861), Expect = 3e-92
Identities = 181/365 (49%), Positives = 241/365 (66%), Gaps = 10/365 (2%)
Query: 21 CWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSIIT 80
C S + YET K +VV++ +G++ R VQLLI+ YFV +VF+ +K+YQ +T ESS++T
Sbjct: 3 CISDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVT 62
Query: 81 KVKGITTSEHKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIRVHNATCLSDA 140
KVKG ++V DV +YV PP+G SVF IIT++ T +Q QG CPES + C+SD+
Sbjct: 63 KVKGSGLYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPESEEKYR--CVSDS 120
Query: 141 DCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAPNFTILIK 200
C G + G G+ TGRCV Y +TCE+ GWCP E +V + A NFTI IK
Sbjct: 121 QC--GPERLPGGGILTGRCV-NYSSVLRTCEIQGWCPTEVD-TVETPIMMEAENFTIFIK 176
Query: 201 NSIHYPKFHFSKGN-IADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKG 259
NSI +P F+F KGN + + T +K C FH D +CPI ++G +V+ AG+ F +LA G
Sbjct: 177 NSIRFPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQDFAKLARTG 236
Query: 260 GVIGVIINWDCDLDLPASECNPKYSFRRLD--PKHVPASSGYNFRFAKYYKI-NGTTTRT 316
GV+G+ I W CDLD +C PKYSF RLD + S GYNFRFAKYYK+ NG+ RT
Sbjct: 237 GVLGIKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYKMENGSEYRT 296
Query: 317 LIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSHK 376
L+KA+GIR DV+V+G AGKF++IPTII+ A TSVGVG+ LCD ILL F+ Y K
Sbjct: 297 LLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKAK 356
Query: 377 KFDKV 381
KF++V
Sbjct: 357 KFEEV 361
>gi|28416933 purinergic receptor P2X5 isoform A [Homo sapiens]
Length = 422
Score = 305 bits (781), Expect = 6e-83
Identities = 169/437 (38%), Positives = 249/437 (56%), Gaps = 41/437 (9%)
Query: 19 RGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSI 78
+G +L+DY+T K ++ +N+++G+LYR +Q IL Y V +VF+++K YQ+ +T +S++
Sbjct: 7 KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAV 66
Query: 79 ITKVKGIT---TSE--HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIRVHN 133
ITKVKG+ TS+ ++WDV +YV P +G +VF ++T + T +Q Q C E+ + +
Sbjct: 67 ITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAENEGIPD 126
Query: 134 ATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAP 193
C D+DC AGE GNG++TGRC+ TCE+F WCP+E + + A
Sbjct: 127 GACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAE 186
Query: 194 NFTILIKNSIHYPKFHFSKGNIADRTD-GYLKRCTFHEASDLYCPIFKLGFIVEKAGESF 252
+FTI IKN I +PKF+FSK N+ D D +LK C F + YCPIF+LG ++ AG F
Sbjct: 187 DFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDF 245
Query: 253 TELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK-IN 310
++A +GGVIG+ I W+CDLD ASEC+P YSF RLD K SSGYNFRFA+YY+
Sbjct: 246 QDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAA 305
Query: 311 GTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKN 370
G RTL+KAYGIR DV+V+G+ G+F CD +L+ + K
Sbjct: 306 GVEFRTLMKAYGIRFDVMVNGK----------------------GAFFCDLVLIYLIKKR 343
Query: 371 KVYSHKKFDKV-----CTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQ- 424
+ Y KK+++V + + + L+ L P G + + PP + G
Sbjct: 344 EFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSS 403
Query: 425 ----QGAECGPAFPPLR 437
G+ C P R
Sbjct: 404 SQKGNGSVCPQLLEPHR 420
>gi|4505545 purinergic receptor P2X1 [Homo sapiens]
Length = 399
Score = 299 bits (765), Expect = 4e-81
Identities = 149/373 (39%), Positives = 233/373 (62%), Gaps = 14/373 (3%)
Query: 14 ARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETG 73
ARR + L++Y+TP++++VRN+++GV++R +QL++L+Y + +VF+ +K YQ S +G
Sbjct: 2 ARRFQEELAAFLFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFLYEKGYQTS-SG 60
Query: 74 PESSIITKVKGITTSE-----HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPES 128
SS+ K+KG+ ++ +VWDV +YV P +G + F ++T T QTQG C E
Sbjct: 61 LISSVSVKLKGLAVTQLPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAE- 119
Query: 129 IRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQ-F 187
C D+ C G+ G+RTG+CV + KTCE+FGWCPVE + +
Sbjct: 120 -HPEGGICKEDSGCTPGKAKRKAQGIRTGKCVAF-NDTVKTCEIFGWCPVEVDDDIPRPA 177
Query: 188 LGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDG-YLKRCTFHEASDLYCPIFKLGFIVE 246
L A NFT+ IKNSI +P+F ++ N+ + + ++K C FH+ CP+F+LG++V+
Sbjct: 178 LLREAENFTLFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQ 237
Query: 247 KAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRL-DPKHVPASSGYNFRFAK 305
++G++F+ LA KGGV+G+ I+W CDLD C P Y F L + K++ S G+NFRFA+
Sbjct: 238 ESGQNFSTLAEKGGVVGITIDWHCDLDWHVRHCRPIYEFHGLYEEKNL--SPGFNFRFAR 295
Query: 306 YYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLT 365
++ NGT R L K +GIR D++V G+AGKF +IPT+ + + + GV + LCD +LL
Sbjct: 296 HFVENGTNYRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLH 355
Query: 366 FMNKNKVYSHKKF 378
+ K Y KKF
Sbjct: 356 ILPKRHYYKQKKF 368
>gi|157419148 purinergic receptor P2X6 isoform 1 [Homo sapiens]
Length = 441
Score = 296 bits (759), Expect = 2e-80
Identities = 171/440 (38%), Positives = 244/440 (55%), Gaps = 24/440 (5%)
Query: 10 AGATARRLARGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQE 69
AG+ A W L DY+T K ++ RN R+G L R +Q I++Y V + + +K YQE
Sbjct: 8 AGSMGSPGATTGWGLL-DYKTEKYVMTRNWRVGALQRLLQFGIVVYVVGWALLAKKGYQE 66
Query: 70 SETGPESSIITKVKGITTSE-----HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGT 124
+ P+ SIITK+KG++ ++ +++WDV ++VKPP+G +VF ++T T +Q QG
Sbjct: 67 RDLEPQFSIITKLKGVSVTQIKELGNRLWDVADFVKPPQGENVFFLVTNFLVTPAQVQGR 126
Query: 125 CPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASV 184
CPE V A C D DC GE +G++TG+CV + G +TCE++ WCPVE G
Sbjct: 127 CPEHPSVPLANCWVDEDCPEGEGGTHSHGVKTGQCV-VFNGTHRTCEIWSWCPVESGVVP 185
Query: 185 SQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDG-YLKRCTFHEASDLYCPIFKLGF 243
S+ L A NFT+ IKN++ + KF+FSK N + D Y K C + YCP+F++G
Sbjct: 186 SRPLLAQAQNFTLFIKNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQFSPYCPVFRIGD 245
Query: 244 IVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKHVPASSGYNFRF 303
+V KAG +F +LA GG +G+ ++WDCDLD S C P YSF+ + YNFR
Sbjct: 246 LVAKAGGTFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSFQLQE-------KSYNFRT 298
Query: 304 A-KYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWI 362
A +++ G RTL+K YGIR D++V GQAGKF LIPT + L T +GV +F CD +
Sbjct: 299 ATHWWEQPGVEARTLLKLYGIRFDILVTGQAGKFGLIPTAVTLGTGAAWLGVVTFFCDLL 358
Query: 363 LLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQE 422
LL + Y K+++ P + S LA E RS P+P +
Sbjct: 359 LLYVDREAHFYWRTKYEEAKAPKATANSVWRELALASQARLAECLRRS--SAPAPTATAA 416
Query: 423 GQQGAECGPAFPPLRPCPIS 442
G Q P PCP S
Sbjct: 417 GSQ------TQTPGWPCPSS 430
>gi|227116341 purinergic receptor P2X6 isoform 2 [Homo sapiens]
Length = 415
Score = 269 bits (687), Expect = 5e-72
Identities = 152/391 (38%), Positives = 217/391 (55%), Gaps = 23/391 (5%)
Query: 59 YVFIVQKSYQESETGPESSIITKVKGITTSE-----HKVWDVEEYVKPPEGGSVFSIITR 113
+ + +K YQE + P+ SIITK+KG++ ++ +++WDV ++VKPP+G +VF ++T
Sbjct: 30 WALLAKKGYQERDLEPQFSIITKLKGVSVTQIKELGNRLWDVADFVKPPQGENVFFLVTN 89
Query: 114 VEATHSQTQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVF 173
T +Q QG CPE V A C D DC GE +G++TG+CV + G +TCE++
Sbjct: 90 FLVTPAQVQGRCPEHPSVPLANCWVDEDCPEGEGGTHSHGVKTGQCV-VFNGTHRTCEIW 148
Query: 174 GWCPVEDGASVSQFLGTMAPNFTILIKNSIHYPKFHFSKGNIADRTDG-YLKRCTFHEAS 232
WCPVE G S+ L A NFT+ IKN++ + KF+FSK N + D Y K C +
Sbjct: 149 SWCPVESGVVPSRPLLAQAQNFTLFIKNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQF 208
Query: 233 DLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPKH 292
YCP+F++G +V KAG +F +LA GG +G+ ++WDCDLD S C P YSF+ +
Sbjct: 209 SPYCPVFRIGDLVAKAGGTFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSFQLQE--- 265
Query: 293 VPASSGYNFRFA-KYYKINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTS 351
YNFR A +++ G RTL+K YGIR D++V GQAGKF LIPT + L T
Sbjct: 266 ----KSYNFRTATHWWEQPGVEARTLLKLYGIRFDILVTGQAGKFGLIPTAVTLGTGAAW 321
Query: 352 VGVGSFLCDWILLTFMNKNKVYSHKKFDKVCTPSHPSGSWPVTLARVLGQAPPEPGHRSE 411
+GV +F CD +LL + Y K+++ P + S LA E RS
Sbjct: 322 LGVVTFFCDLLLLYVDREAHFYWRTKYEEAKAPKATANSVWRELALASQARLAECLRRS- 380
Query: 412 DQHPSPPSGQEGQQGAECGPAFPPLRPCPIS 442
P+P + G Q P PCP S
Sbjct: 381 -SAPAPTATAAGSQ------TQTPGWPCPSS 404
>gi|28416935 purinergic receptor P2X5 isoform B [Homo sapiens]
Length = 397
Score = 269 bits (687), Expect = 5e-72
Identities = 158/436 (36%), Positives = 234/436 (53%), Gaps = 64/436 (14%)
Query: 19 RGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSI 78
+G +L+DY+T K ++ +N+++G+LYR +Q IL Y V +VF+++K YQ+ +T +S++
Sbjct: 7 KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAV 66
Query: 79 ITKVKGIT---TSE--HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIRVHN 133
ITKVKG+ TS+ ++WDV +YV P +Q +G + +
Sbjct: 67 ITKVKGVAFTNTSDLGQRIWDVADYVIP-----------------AQNEG-------IPD 102
Query: 134 ATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQFLGTMAP 193
C D+DC AGE GNG++TGRC+ TCE+F WCP+E + + A
Sbjct: 103 GACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEPFLKEAE 162
Query: 194 NFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFT 253
+FTI IKN I +PKF+FS + + +LK C F + YCPIF+LG ++ AG F
Sbjct: 163 DFTIFIKNHIRFPKFNFSNNVMDVKDRSFLKSCHFGPKNH-YCPIFRLGSVIRWAGSDFQ 221
Query: 254 ELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK-HVPASSGYNFRFAKYYK-ING 311
++A +GGVIG+ I W+CDLD ASEC+P YSF RLD K SSGYNFRFA+YY+ G
Sbjct: 222 DIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARYYRDAAG 281
Query: 312 TTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNK 371
RTL+KAYGIR DV+V+G+ G+F CD +L+ + K +
Sbjct: 282 VEFRTLMKAYGIRFDVMVNGK----------------------GAFFCDLVLIYLIKKRE 319
Query: 372 VYSHKKFDKV-----CTPSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQ-- 424
Y KK+++V + + + L+ L P G + + PP + G
Sbjct: 320 FYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSS 379
Query: 425 ---QGAECGPAFPPLR 437
G+ C P R
Sbjct: 380 QKGNGSVCPQLLEPHR 395
>gi|29294631 purinergic receptor P2X7 [Homo sapiens]
Length = 595
Score = 241 bits (616), Expect = 8e-64
Identities = 145/378 (38%), Positives = 207/378 (54%), Gaps = 25/378 (6%)
Query: 23 SALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSIITKV 82
S ++ YET KV +++ G + ++I Y V + + K YQ E SS+ TKV
Sbjct: 8 SDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSY-VCFALVSDKLYQRKEP-VISSVHTKV 65
Query: 83 KGITTSE------------HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIR 130
KGI + H V+D +Y P +G S F ++T T Q Q CPE
Sbjct: 66 KGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQGNSFF-VMTNFLKTEGQEQRLCPE-YP 123
Query: 131 VHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQ-FLG 189
C SD C G +D G++TGRCV Y+G KTCEV WCP+E + L
Sbjct: 124 TRRTLCSSDRGCKKGWMDPQSKGIQTGRCV-VYEGNQKTCEVSAWCPIEAVEEAPRPALL 182
Query: 190 TMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAG 249
A NFT+LIKN+I +P +++ NI G CTFH+ + CPIF+LG I + G
Sbjct: 183 NSAENFTVLIKNNIDFPGHNYTTRNILP---GLNITCTFHKTQNPQCPIFRLGDIFRETG 239
Query: 250 ESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK--HVPASSGYNFRFAKYY 307
++F+++A +GG++G+ I WDC+LD C PKYSFRRLD K +V GYNFR+AKYY
Sbjct: 240 DNFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYY 299
Query: 308 KINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFM 367
K N RTLIK +GIR D++V G GKF +I ++ + + L+ G+ + D+++ T+
Sbjct: 300 KENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTY- 358
Query: 368 NKNKVYSH-KKFDKVCTP 384
+ N SH + K C P
Sbjct: 359 SSNCCRSHIYPWCKCCQP 376
>gi|28416937 purinergic receptor P2X5 isoform C [Homo sapiens]
Length = 178
Score = 148 bits (373), Expect = 1e-35
Identities = 68/166 (40%), Positives = 109/166 (65%), Gaps = 5/166 (3%)
Query: 19 RGCWSALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSI 78
+G +L+DY+T K ++ +N+++G+LYR +Q IL Y V +VF+++K YQ+ +T +S++
Sbjct: 7 KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAV 66
Query: 79 ITKVKGIT---TSE--HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIRVHN 133
ITKVKG+ TS+ ++WDV +YV P +G +VF ++T + T +Q Q C E+ + +
Sbjct: 67 ITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAENEGIPD 126
Query: 134 ATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVE 179
C D+DC AGE GNG++TGRC+ TCE+F WCP+E
Sbjct: 127 GACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLE 172
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 38.1 bits (87), Expect = 0.017
Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 18/90 (20%)
Query: 384 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 443
PS PS S P P PG PP+ Q G + ++ GPA PP +P ++
Sbjct: 296 PSLPSPSKPPI-------QQPTPG--------KPPAQQPGHEKSQPGPAKPPAQPSGLTK 340
Query: 444 PSEQM---VDTPASEPAQASTPTDPKGLAQ 470
P Q V P P P P G A+
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAK 370
Score = 30.8 bits (68), Expect = 2.8
Identities = 30/103 (29%), Positives = 36/103 (34%), Gaps = 27/103 (26%)
Query: 384 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 443
P+ PSG L + L Q P + P P G GPA PP +
Sbjct: 332 PAQPSG-----LTKPLAQQP------GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380
Query: 444 PSEQMVD------------TPASEPAQASTPTD----PKGLAQ 470
PS + TPA +P A PT PK LAQ
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423
Score = 29.6 bits (65), Expect = 6.2
Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 5/72 (6%)
Query: 400 GQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFP-PLRPCPISAPSEQMVDTPASEPAQ 458
G A P P + PS G + GPA P P +P PS+Q P S
Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ----PGSAKPS 540
Query: 459 ASTPTDPKGLAQ 470
A P+ K AQ
Sbjct: 541 AQQPSPAKPSAQ 552
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 38.1 bits (87), Expect = 0.017
Identities = 28/90 (31%), Positives = 36/90 (40%), Gaps = 18/90 (20%)
Query: 384 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 443
PS PS S P P PG PP+ Q G + ++ GPA PP +P ++
Sbjct: 296 PSLPSPSKPPI-------QQPTPG--------KPPAQQPGHEKSQPGPAKPPAQPSGLTK 340
Query: 444 PSEQM---VDTPASEPAQASTPTDPKGLAQ 470
P Q V P P P P G A+
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAK 370
Score = 30.8 bits (68), Expect = 2.8
Identities = 30/103 (29%), Positives = 36/103 (34%), Gaps = 27/103 (26%)
Query: 384 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 443
P+ PSG L + L Q P + P P G GPA PP +
Sbjct: 332 PAQPSG-----LTKPLAQQP------GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380
Query: 444 PSEQMVD------------TPASEPAQASTPTD----PKGLAQ 470
PS + TPA +P A PT PK LAQ
Sbjct: 381 PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423
Score = 29.6 bits (65), Expect = 6.2
Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 5/72 (6%)
Query: 400 GQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFP-PLRPCPISAPSEQMVDTPASEPAQ 458
G A P P + PS G + GPA P P +P PS+Q P S
Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ----PGSAKPS 540
Query: 459 ASTPTDPKGLAQ 470
A P+ K AQ
Sbjct: 541 AQQPSPAKPSAQ 552
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 37.0 bits (84), Expect = 0.039
Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 7/86 (8%)
Query: 384 PSHPSGSWPVTLARVLGQ---APPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCP 440
P + +G P TL R + + APP+PG + P P GQ ++ P+ P P
Sbjct: 618 PHNAAGPSPHTLRRAVKKPAPAPPKPG----NPPPGHPGGQSSSGTSQHPPSLSPKPPTR 673
Query: 441 ISAPSEQMVDTPASEPAQASTPTDPK 466
+P Q P +P+ S + P+
Sbjct: 674 SPSPPTQHTGQPPGQPSAPSQLSAPR 699
Score = 32.0 bits (71), Expect = 1.2
Identities = 25/87 (28%), Positives = 31/87 (35%), Gaps = 15/87 (17%)
Query: 384 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 443
P HP G + Q PP + + PSPP+ GQ P P P +SA
Sbjct: 648 PGHPGGQ----SSSGTSQHPPSLSPKPPTRSPSPPTQHTGQ------PPGQPSAPSQLSA 697
Query: 444 P-----SEQMVDTPASEPAQASTPTDP 465
P S + P P Q T P
Sbjct: 698 PRRYSSSLSPIQAPNHPPPQPPTQATP 724
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 37.0 bits (84), Expect = 0.039
Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 7/86 (8%)
Query: 384 PSHPSGSWPVTLARVLGQ---APPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCP 440
P + +G P TL R + + APP+PG + P P GQ ++ P+ P P
Sbjct: 540 PHNAAGPSPHTLRRAVKKPAPAPPKPG----NPPPGHPGGQSSSGTSQHPPSLSPKPPTR 595
Query: 441 ISAPSEQMVDTPASEPAQASTPTDPK 466
+P Q P +P+ S + P+
Sbjct: 596 SPSPPTQHTGQPPGQPSAPSQLSAPR 621
Score = 32.0 bits (71), Expect = 1.2
Identities = 25/87 (28%), Positives = 31/87 (35%), Gaps = 15/87 (17%)
Query: 384 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 443
P HP G + Q PP + + PSPP+ GQ P P P +SA
Sbjct: 570 PGHPGGQ----SSSGTSQHPPSLSPKPPTRSPSPPTQHTGQ------PPGQPSAPSQLSA 619
Query: 444 P-----SEQMVDTPASEPAQASTPTDP 465
P S + P P Q T P
Sbjct: 620 PRRYSSSLSPIQAPNHPPPQPPTQATP 646
>gi|23397666 transcriptional co-repressor Sin3A [Homo sapiens]
Length = 1273
Score = 36.6 bits (83), Expect = 0.051
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 3/58 (5%)
Query: 405 EPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTP 462
+P + QHPS PS Q A+ P PP + +S PS+ TPAS+ P
Sbjct: 217 QPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAK---VSKPSQLQAHTPASQQTPPLPP 271
>gi|223941785 transcriptional co-repressor Sin3A [Homo sapiens]
Length = 1273
Score = 36.6 bits (83), Expect = 0.051
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 3/58 (5%)
Query: 405 EPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTP 462
+P + QHPS PS Q A+ P PP + +S PS+ TPAS+ P
Sbjct: 217 QPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAK---VSKPSQLQAHTPASQQTPPLPP 271
>gi|223941782 transcriptional co-repressor Sin3A [Homo sapiens]
Length = 1273
Score = 36.6 bits (83), Expect = 0.051
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 3/58 (5%)
Query: 405 EPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSEQMVDTPASEPAQASTP 462
+P + QHPS PS Q A+ P PP + +S PS+ TPAS+ P
Sbjct: 217 QPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAK---VSKPSQLQAHTPASQQTPPLPP 271
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 36.2 bits (82), Expect = 0.066
Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 11/78 (14%)
Query: 403 PPEPGHRSEDQHPSPPS--GQEGQQGAECGPA-----FPPLRPCPISAP---SEQMVDTP 452
PP+P + + Q P PP+ G EG A C P P L P P E+ +
Sbjct: 522 PPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPS 581
Query: 453 ASEPAQASTPT-DPKGLA 469
+ +Q+ TPT PKGLA
Sbjct: 582 SGYSSQSGTPTLPPKGLA 599
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 35.8 bits (81), Expect = 0.086
Identities = 27/86 (31%), Positives = 36/86 (41%), Gaps = 5/86 (5%)
Query: 381 VCTPSHPSGSWPVT-LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPC 439
V P P S PV+ A QAPP PSPP+ A P PP
Sbjct: 673 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP---- 728
Query: 440 PISAPSEQMVDTPASEPAQASTPTDP 465
P++AP Q+ +P + P + + T P
Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPP 754
Score = 29.3 bits (64), Expect = 8.1
Identities = 27/88 (30%), Positives = 31/88 (35%), Gaps = 3/88 (3%)
Query: 384 PSHPSGSWPVT-LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPC-PI 441
P P S P++ A QAPP PSPP+ A P PPL P+
Sbjct: 707 PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPL 766
Query: 442 SAPSEQMVDTPASEPAQASTPTDPKGLA 469
P P S P P P LA
Sbjct: 767 QVPPSPPASLPMS-PLAKPPPQAPPALA 793
>gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]
Length = 1337
Score = 35.8 bits (81), Expect = 0.086
Identities = 23/79 (29%), Positives = 29/79 (36%), Gaps = 19/79 (24%)
Query: 384 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 443
P PS P+ + PP P H+ P PP C P PP PCP +
Sbjct: 84 PMPPSAQGPLPPCPI---RPPFPNHQMRHPFPVPP----------CFPPMPPPMPCPNNP 130
Query: 444 PSEQMVDTPASEPAQASTP 462
P P + P Q + P
Sbjct: 131 P------VPGAPPGQGTFP 143
>gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]
Length = 1374
Score = 35.8 bits (81), Expect = 0.086
Identities = 23/79 (29%), Positives = 29/79 (36%), Gaps = 19/79 (24%)
Query: 384 PSHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISA 443
P PS P+ + PP P H+ P PP C P PP PCP +
Sbjct: 84 PMPPSAQGPLPPCPI---RPPFPNHQMRHPFPVPP----------CFPPMPPPMPCPNNP 130
Query: 444 PSEQMVDTPASEPAQASTP 462
P P + P Q + P
Sbjct: 131 P------VPGAPPGQGTFP 143
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 35.4 bits (80), Expect = 0.11
Identities = 27/83 (32%), Positives = 33/83 (39%), Gaps = 5/83 (6%)
Query: 381 VCTPSHPSGSWPVT-LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPC 439
V P P S PV+ A QAPP PSPP+ A P PP
Sbjct: 448 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP---- 503
Query: 440 PISAPSEQMVDTPASEPAQASTP 462
P++AP Q+ P P +TP
Sbjct: 504 PLAAPPLQLAKPPPQAPPALATP 526
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 35.4 bits (80), Expect = 0.11
Identities = 27/83 (32%), Positives = 33/83 (39%), Gaps = 5/83 (6%)
Query: 381 VCTPSHPSGSWPVT-LARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPC 439
V P P S PV+ A QAPP PSPP+ A P PP
Sbjct: 409 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP---- 464
Query: 440 PISAPSEQMVDTPASEPAQASTP 462
P++AP Q+ P P +TP
Sbjct: 465 PLAAPPLQLAKPPPQAPPALATP 487
Score = 30.0 bits (66), Expect = 4.7
Identities = 21/81 (25%), Positives = 33/81 (40%), Gaps = 2/81 (2%)
Query: 385 SHPSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAP 444
S P+ S P AR +AP P + Q + PA PL P++ P
Sbjct: 241 SSPARSGPS--ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 298
Query: 445 SEQMVDTPASEPAQASTPTDP 465
S +P++ P+ + P+ P
Sbjct: 299 SPSAPPSPSAPPSLQTLPSPP 319
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 35.4 bits (80), Expect = 0.11
Identities = 23/83 (27%), Positives = 31/83 (37%)
Query: 387 PSGSWPVTLARVLGQAPPEPGHRSEDQHPSPPSGQEGQQGAECGPAFPPLRPCPISAPSE 446
PS + P+ VL +P + Q P P G A P P P+ APS
Sbjct: 1600 PSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSS 1659
Query: 447 QMVDTPASEPAQASTPTDPKGLA 469
PA P+ +P + LA
Sbjct: 1660 TQTMLPAPVPSPLPSPASTQTLA 1682
>gi|39812378 RAN binding protein 9 [Homo sapiens]
Length = 729
Score = 34.7 bits (78), Expect = 0.19
Identities = 31/86 (36%), Positives = 34/86 (39%), Gaps = 8/86 (9%)
Query: 392 PVTLARVLGQAPPEPGHRSEDQHPS-PPSGQEGQQGAECGPA----FPPLRPCPISA--- 443
P LA V G P P S P+ P G G +G A PP P P +A
Sbjct: 24 PAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLHPPPPPPPATAAPP 83
Query: 444 PSEQMVDTPASEPAQASTPTDPKGLA 469
P PAS A AS P P GLA
Sbjct: 84 PPPPPPPPPASAAAPASGPPAPPGLA 109
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,511,385
Number of Sequences: 37866
Number of extensions: 1041451
Number of successful extensions: 5403
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 149
Number of HSP's that attempted gapping in prelim test: 4978
Number of HSP's gapped (non-prelim): 504
length of query: 471
length of database: 18,247,518
effective HSP length: 106
effective length of query: 365
effective length of database: 14,233,722
effective search space: 5195308530
effective search space used: 5195308530
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.