Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 122056683
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122056683 FRAS1 related extracellular matrix 1 [Homo
sapiens]
(2179 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122056683 FRAS1 related extracellular matrix 1 [Homo sapiens] 4443 0.0
gi|79749430 FRAS1-related extracellular matrix protein 2 precurs... 965 0.0
gi|169167211 PREDICTED: FRAS1 related extracellular matrix 3 [Ho... 852 0.0
gi|169166904 PREDICTED: FRAS1 related extracellular matrix 3 [Ho... 852 0.0
gi|169166334 PREDICTED: FRAS1 related extracellular matrix 3 [Ho... 851 0.0
gi|108773804 Fraser syndrome 1 [Homo sapiens] 525 e-148
gi|47419930 chondroitin sulfate proteoglycan 4 [Homo sapiens] 192 2e-48
gi|4505245 mannose receptor C type 1 precursor [Homo sapiens] 65 7e-10
gi|126090883 aggrecan isoform 1 precursor [Homo sapiens] 64 1e-09
gi|126090892 aggrecan isoform 2 precursor [Homo sapiens] 63 3e-09
gi|57546917 mannose receptor, C type 1-like 1 [Homo sapiens] 62 6e-09
gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens] 61 1e-08
gi|187607300 versican isoform 2 [Homo sapiens] 60 2e-08
gi|21361116 versican isoform 1 [Homo sapiens] 60 2e-08
gi|144446030 lymphocyte antigen 75 [Homo sapiens] 59 7e-08
gi|18641360 collectin sub-family member 12 [Homo sapiens] 58 1e-07
gi|20149533 Fc fragment of IgE, low affinity II, receptor for (C... 57 3e-07
gi|10835248 regenerating islet-derived 1 beta precursor [Homo sa... 56 4e-07
gi|110624774 mannose receptor, C type 2 [Homo sapiens] 55 6e-07
gi|33667103 C-type lectin, superfamily member 14 isoform 1 [Homo... 52 5e-06
gi|53832016 C-type lectin, superfamily member 14 isoform 2 [Homo... 52 5e-06
gi|113722120 G protein-coupled receptor 98 precursor [Homo sapiens] 52 6e-06
gi|29725633 regenerating islet-derived 1 alpha precursor [Homo s... 52 6e-06
gi|4502251 asialoglycoprotein receptor 1 [Homo sapiens] 52 6e-06
gi|38348296 C-type lectin domain family 4, member G [Homo sapiens] 52 8e-06
gi|38372935 brevican isoform 1 [Homo sapiens] 51 1e-05
gi|21070995 pancreatitis-associated protein precursor [Homo sapi... 51 1e-05
gi|21070993 pancreatitis-associated protein precursor [Homo sapi... 51 1e-05
gi|4505605 pancreatitis-associated protein precursor [Homo sapiens] 51 1e-05
gi|18426877 asialoglycoprotein receptor 2 isoform c [Homo sapiens] 49 7e-05
>gi|122056683 FRAS1 related extracellular matrix 1 [Homo sapiens]
Length = 2179
Score = 4443 bits (11524), Expect = 0.0
Identities = 2179/2179 (100%), Positives = 2179/2179 (100%)
Query: 1 MNSLSWGAANAVLLLLLLAWASPTFISINRGVRVMKGHSAFLSGDDLKFAIPKEKDACKV 60
MNSLSWGAANAVLLLLLLAWASPTFISINRGVRVMKGHSAFLSGDDLKFAIPKEKDACKV
Sbjct: 1 MNSLSWGAANAVLLLLLLAWASPTFISINRGVRVMKGHSAFLSGDDLKFAIPKEKDACKV 60
Query: 61 EVVMNEPITQRVGKLTPQVFDCHFLPNEVKYVHNGCPILDEDTVKLRLYRFTERDTFIET 120
EVVMNEPITQRVGKLTPQVFDCHFLPNEVKYVHNGCPILDEDTVKLRLYRFTERDTFIET
Sbjct: 61 EVVMNEPITQRVGKLTPQVFDCHFLPNEVKYVHNGCPILDEDTVKLRLYRFTERDTFIET 120
Query: 121 FILWVYLLEPDCNIIHMSNNVLEVPEFNGLSQAIDKNLLRFDYDRMASLECTVSLDTART 180
FILWVYLLEPDCNIIHMSNNVLEVPEFNGLSQAIDKNLLRFDYDRMASLECTVSLDTART
Sbjct: 121 FILWVYLLEPDCNIIHMSNNVLEVPEFNGLSQAIDKNLLRFDYDRMASLECTVSLDTART 180
Query: 181 RLPAHGQMVLGEPRPEEPRGDQPHSFFPESQLRAKLKCPGGSCTPGLKKIGSLKVSCEEF 240
RLPAHGQMVLGEPRPEEPRGDQPHSFFPESQLRAKLKCPGGSCTPGLKKIGSLKVSCEEF
Sbjct: 181 RLPAHGQMVLGEPRPEEPRGDQPHSFFPESQLRAKLKCPGGSCTPGLKKIGSLKVSCEEF 240
Query: 241 LLMGLRYQHLDPPSPNIDYISIQLDLTDTRSKIVYKSESAWLPVYIRAGIPNQIPKAAFM 300
LLMGLRYQHLDPPSPNIDYISIQLDLTDTRSKIVYKSESAWLPVYIRAGIPNQIPKAAFM
Sbjct: 241 LLMGLRYQHLDPPSPNIDYISIQLDLTDTRSKIVYKSESAWLPVYIRAGIPNQIPKAAFM 300
Query: 301 AVFILEVDQFILTSLTTSVLDCEEDETPKPLLVFNITKAPLQGYVTHLLDHTRPISSFTW 360
AVFILEVDQFILTSLTTSVLDCEEDETPKPLLVFNITKAPLQGYVTHLLDHTRPISSFTW
Sbjct: 301 AVFILEVDQFILTSLTTSVLDCEEDETPKPLLVFNITKAPLQGYVTHLLDHTRPISSFTW 360
Query: 361 KDLSDMQIAYQPPNSSHSERRHDEVELEVYDFFFERSAPMTVHISIRTADTNAPRVSWNT 420
KDLSDMQIAYQPPNSSHSERRHDEVELEVYDFFFERSAPMTVHISIRTADTNAPRVSWNT
Sbjct: 361 KDLSDMQIAYQPPNSSHSERRHDEVELEVYDFFFERSAPMTVHISIRTADTNAPRVSWNT 420
Query: 421 GLSLLEGQSRAITWEQFQVVDNDDIGAVRLVTVGGLQHGWLTLRGGKGFLFTVADLQAGV 480
GLSLLEGQSRAITWEQFQVVDNDDIGAVRLVTVGGLQHGWLTLRGGKGFLFTVADLQAGV
Sbjct: 421 GLSLLEGQSRAITWEQFQVVDNDDIGAVRLVTVGGLQHGWLTLRGGKGFLFTVADLQAGV 480
Query: 481 VRYHHDDSDSTKDFVVFRIFDGHHSIRHKFPINVLPKDDSPPFLITNVVIELEEGQTILI 540
VRYHHDDSDSTKDFVVFRIFDGHHSIRHKFPINVLPKDDSPPFLITNVVIELEEGQTILI
Sbjct: 481 VRYHHDDSDSTKDFVVFRIFDGHHSIRHKFPINVLPKDDSPPFLITNVVIELEEGQTILI 540
Query: 541 QGSMLRASDVDASDDYIFFNITKPPQAGEIMKKPGPGLIGYPVHGFLQRDLFNGIIYYRH 600
QGSMLRASDVDASDDYIFFNITKPPQAGEIMKKPGPGLIGYPVHGFLQRDLFNGIIYYRH
Sbjct: 541 QGSMLRASDVDASDDYIFFNITKPPQAGEIMKKPGPGLIGYPVHGFLQRDLFNGIIYYRH 600
Query: 601 FGGEIFEDSFQFVLWDSHEPPNLSVPQVATIHITPVDDQLPKEAPGVSRHLVVKETEVAY 660
FGGEIFEDSFQFVLWDSHEPPNLSVPQVATIHITPVDDQLPKEAPGVSRHLVVKETEVAY
Sbjct: 601 FGGEIFEDSFQFVLWDSHEPPNLSVPQVATIHITPVDDQLPKEAPGVSRHLVVKETEVAY 660
Query: 661 ITKKQLHFIDSESYDRELVYTITTPPFFSFSHRHLDAGKLFMVDSIPKVVKNPTALELRS 720
ITKKQLHFIDSESYDRELVYTITTPPFFSFSHRHLDAGKLFMVDSIPKVVKNPTALELRS
Sbjct: 661 ITKKQLHFIDSESYDRELVYTITTPPFFSFSHRHLDAGKLFMVDSIPKVVKNPTALELRS 720
Query: 721 FTQHAVNYMKVAYMPPMQDIGPHCRDVQFTFSVSNQHGGTLHGICFNITILPVDNQVPEA 780
FTQHAVNYMKVAYMPPMQDIGPHCRDVQFTFSVSNQHGGTLHGICFNITILPVDNQVPEA
Sbjct: 721 FTQHAVNYMKVAYMPPMQDIGPHCRDVQFTFSVSNQHGGTLHGICFNITILPVDNQVPEA 780
Query: 781 FTNPLKVTEGGQSIISTEHILISDADTKLDNIDLSLRELPLHGRVELNGFPLNSGGTFSW 840
FTNPLKVTEGGQSIISTEHILISDADTKLDNIDLSLRELPLHGRVELNGFPLNSGGTFSW
Sbjct: 781 FTNPLKVTEGGQSIISTEHILISDADTKLDNIDLSLRELPLHGRVELNGFPLNSGGTFSW 840
Query: 841 GDLHTLKVRYQHDGTEVLQDDLLLEVTDGTNSAEFVLHVEVFPVNDEPPVLKADLMPVMN 900
GDLHTLKVRYQHDGTEVLQDDLLLEVTDGTNSAEFVLHVEVFPVNDEPPVLKADLMPVMN
Sbjct: 841 GDLHTLKVRYQHDGTEVLQDDLLLEVTDGTNSAEFVLHVEVFPVNDEPPVLKADLMPVMN 900
Query: 901 CSEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHGVVRRAGVTVDQFSQRDVISEAVT 960
CSEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHGVVRRAGVTVDQFSQRDVISEAVT
Sbjct: 901 CSEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHGVVRRAGVTVDQFSQRDVISEAVT 960
Query: 961 YKHTGGEIGLMPCFDTITLVVSDGEAGPFVNGCCYNGPNPSVPLHASFPVYDLNITVYPV 1020
YKHTGGEIGLMPCFDTITLVVSDGEAGPFVNGCCYNGPNPSVPLHASFPVYDLNITVYPV
Sbjct: 961 YKHTGGEIGLMPCFDTITLVVSDGEAGPFVNGCCYNGPNPSVPLHASFPVYDLNITVYPV 1020
Query: 1021 DNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSV 1080
DNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSV
Sbjct: 1021 DNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSV 1080
Query: 1081 GFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSII 1140
GFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSII
Sbjct: 1081 GFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSII 1140
Query: 1141 INPTNDEAPDFVVQNITVCEGQMKELDSSIISAVDLDIPQDALLFSITQKPRHGLLIDRG 1200
INPTNDEAPDFVVQNITVCEGQMKELDSSIISAVDLDIPQDALLFSITQKPRHGLLIDRG
Sbjct: 1141 INPTNDEAPDFVVQNITVCEGQMKELDSSIISAVDLDIPQDALLFSITQKPRHGLLIDRG 1200
Query: 1201 FSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFTIQLSDGKHKI 1260
FSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFTIQLSDGKHKI
Sbjct: 1201 FSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFTIQLSDGKHKI 1260
Query: 1261 LKTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQ 1320
LKTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQ
Sbjct: 1261 LKTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQ 1320
Query: 1321 NGQLQLKIGRDWVPLSPGMKCTQEEVDLNLLRYTHTGAMDSQNQDSFTFYLWDGNNRSPA 1380
NGQLQLKIGRDWVPLSPGMKCTQEEVDLNLLRYTHTGAMDSQNQDSFTFYLWDGNNRSPA
Sbjct: 1321 NGQLQLKIGRDWVPLSPGMKCTQEEVDLNLLRYTHTGAMDSQNQDSFTFYLWDGNNRSPA 1380
Query: 1381 LDCQITIKDMEKGDIVILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYG 1440
LDCQITIKDMEKGDIVILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYG
Sbjct: 1381 LDCQITIKDMEKGDIVILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYG 1440
Query: 1441 QIEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRTEHGVFEITLE 1500
QIEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRTEHGVFEITLE
Sbjct: 1441 QIEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRTEHGVFEITLE 1500
Query: 1501 TVDRALPVVTRNKGLRLAQGAVGLLSPDLLQLTDPDTPAENLTFLLVQLPQHGQLYLWGT 1560
TVDRALPVVTRNKGLRLAQGAVGLLSPDLLQLTDPDTPAENLTFLLVQLPQHGQLYLWGT
Sbjct: 1501 TVDRALPVVTRNKGLRLAQGAVGLLSPDLLQLTDPDTPAENLTFLLVQLPQHGQLYLWGT 1560
Query: 1561 GLLQHNFTQQDVDSKNVAYRHSGGDSQTDCFTFMATDGTNQGFIVNGRVWEEPVLFTIQV 1620
GLLQHNFTQQDVDSKNVAYRHSGGDSQTDCFTFMATDGTNQGFIVNGRVWEEPVLFTIQV
Sbjct: 1561 GLLQHNFTQQDVDSKNVAYRHSGGDSQTDCFTFMATDGTNQGFIVNGRVWEEPVLFTIQV 1620
Query: 1621 DQLDKTAPRITLLHSPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGH 1680
DQLDKTAPRITLLHSPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGH
Sbjct: 1621 DQLDKTAPRITLLHSPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGH 1680
Query: 1681 LENTTTGEFIHEKFSQKDLNSKTILYIINPSLEVNSDTVEFQIMDPTGNSATPQILELKW 1740
LENTTTGEFIHEKFSQKDLNSKTILYIINPSLEVNSDTVEFQIMDPTGNSATPQILELKW
Sbjct: 1681 LENTTTGEFIHEKFSQKDLNSKTILYIINPSLEVNSDTVEFQIMDPTGNSATPQILELKW 1740
Query: 1741 SHIEWSQTEYEVCENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQF 1800
SHIEWSQTEYEVCENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQF
Sbjct: 1741 SHIEWSQTEYEVCENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQF 1800
Query: 1801 DPGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTKTKAAVKILDSKGGQCHPSYS 1860
DPGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTKTKAAVKILDSKGGQCHPSYS
Sbjct: 1801 DPGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTKTKAAVKILDSKGGQCHPSYS 1860
Query: 1861 SNQSKHSTWEKGIWHLLPPGSSSSTTSGSFHLERRPLPSSMQLAVIRGDTLRGFDSTDLS 1920
SNQSKHSTWEKGIWHLLPPGSSSSTTSGSFHLERRPLPSSMQLAVIRGDTLRGFDSTDLS
Sbjct: 1861 SNQSKHSTWEKGIWHLLPPGSSSSTTSGSFHLERRPLPSSMQLAVIRGDTLRGFDSTDLS 1920
Query: 1921 QRKLRTRGNGKTVRPSSVYRNGTDIIYNYHGIVSLKLEDDSFPTHKRKAKVSIISQPQKT 1980
QRKLRTRGNGKTVRPSSVYRNGTDIIYNYHGIVSLKLEDDSFPTHKRKAKVSIISQPQKT
Sbjct: 1921 QRKLRTRGNGKTVRPSSVYRNGTDIIYNYHGIVSLKLEDDSFPTHKRKAKVSIISQPQKT 1980
Query: 1981 IKVAELPQADKVESTTDSHFPRQDQLPSFPKNCTLELKGLFHFEEGIQKLYQCNGIAWKA 2040
IKVAELPQADKVESTTDSHFPRQDQLPSFPKNCTLELKGLFHFEEGIQKLYQCNGIAWKA
Sbjct: 1981 IKVAELPQADKVESTTDSHFPRQDQLPSFPKNCTLELKGLFHFEEGIQKLYQCNGIAWKA 2040
Query: 2041 WSPQTKDVEDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMR 2100
WSPQTKDVEDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMR
Sbjct: 2041 WSPQTKDVEDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMR 2100
Query: 2101 WLWDIGGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKW 2160
WLWDIGGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKW
Sbjct: 2101 WLWDIGGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKW 2160
Query: 2161 QTKDCRRAKPHNYVCSRKL 2179
QTKDCRRAKPHNYVCSRKL
Sbjct: 2161 QTKDCRRAKPHNYVCSRKL 2179
>gi|79749430 FRAS1-related extracellular matrix protein 2 precursor
[Homo sapiens]
Length = 3169
Score = 965 bits (2495), Expect = 0.0
Identities = 651/1922 (33%), Positives = 980/1922 (50%), Gaps = 133/1922 (6%)
Query: 21 ASPTFISINRGVRVMKGHSAFLSG-DDLKFAIPKEKDACKVEVVMNEPITQRVGKLTPQV 79
A + NRG+RV G +L DL + + D C V V+ N+ + QR G+L+P+
Sbjct: 68 AEEAIVLANRGLRVPFGREVWLDPLHDLVLQV-QPGDRCAVSVLDNDALAQRPGRLSPKR 126
Query: 80 FDCHFLPNEVKYVHNGCPILDEDTVKLRLYRFTERDTFIETFILWVYLLEPDCNIIHMSN 139
F C F P EV+Y H G D V+L+L + +L V ++ ++ N
Sbjct: 127 FPCDFGPGEVRYSHLGARSPSRDRVRLQLRYDAPGGAVVLPLVLEVEVVFTQLEVV-TRN 185
Query: 140 NVLEVPEFNGLSQAIDKNLLRFDYDRMASLECTVSLDTARTRLPAHGQMVLGEPRPEEPR 199
L V E G S A+D L F + EC V + + LP +G+++
Sbjct: 186 LPLVVEELLGTSNALDARSLEFAFQPETE-ECRVGILSGLGALPRYGELL---------- 234
Query: 200 GDQPHSFFPESQLRAKLKCPGGSCTPGLKKIGSLKVSCEEFLLMGLRYQHLDPP-SPNID 258
+P+ PGG+ G + +L + C+ F +G+RY+H SPN D
Sbjct: 235 ------HYPQ--------VPGGAREGGAPE--TLLMDCKAFQELGVRYRHTAASRSPNRD 278
Query: 259 YISIQLDLTDTRSKI---VYKSESAWLPVYIRAGIPNQIPKAAFMAVFILEVDQFILTSL 315
+I + ++L + + K E + V IR G N PK +F+A+ ++EVDQF+LT+L
Sbjct: 279 WIPMVVELRSRGAPVGSPALKREHFQVLVRIRGGAENTAPKPSFVAMMMMEVDQFVLTAL 338
Query: 316 TTSVLDCEEDETPKPLLVFNITKA--PLQGYVTHLLDHTRPISSFTWKDLSDMQIAYQPP 373
T +L E+ E+P LL+FN+T P QGY+ D + P+SSFT +DL ++IAYQPP
Sbjct: 339 TPDMLAAEDAESPSDLLIFNLTSPFQPGQGYLVSTDDRSLPLSSFTQRDLRLLKIAYQPP 398
Query: 374 NSSHSERRHDEVELEVYDFFFERSAPMTVHISIRTADTNAPRVSWNTGLSLLEGQSRAIT 433
+ + R E+ELEV D S P + ++ +T AP V+ NTGL L EGQSR +T
Sbjct: 399 SEDSDQERLFELELEVVDLEGAASDPFAFMVVVKPMNTMAPVVTRNTGLILYEGQSRPLT 458
Query: 434 W------EQFQVVDNDDIGAVRLVTVGGLQHGWLTLRGGKGFL-----FTVADLQAGVVR 482
+ + D DD+ AVRL V GL+HG L + G FTVA+L AG V
Sbjct: 459 GPAGSGPQNLVISDEDDLEAVRLEVVAGLRHGHLVILGASSGSSAPKSFTVAELAAGQVV 518
Query: 483 YHHDDSD-STKDFVVFRIFDG--HHSIRHKFPINVLPKDDSPPFLITNVVIELEEGQTIL 539
Y HDD D S D +V R+ DG H ++ FPI ++P DD PP L N + L EG+T+
Sbjct: 519 YQHDDRDGSLSDNLVLRMVDGGGRHQVQFLFPITLVPVDDQPPVLNANTGLTLAEGETVP 578
Query: 540 IQGSMLRASDVDASDDYIFFNI--------------TKPPQAGE-----IMKKPGPGLIG 580
I L A+D+D+ D + F + T PP + + +K G
Sbjct: 579 ILPLSLSATDMDSDDSLLLFVLESPFLTTGHLLLRQTHPPHEKQELLRGLWRKEG-AFYE 637
Query: 581 YPVHGFLQRDLFNGIIYYRHFGGEI---FEDSFQFVLWDSHEPPNLSVPQVATIHITPVD 637
V + Q+D+ G ++YRH G D F F + D+H+PPN S Q I I PVD
Sbjct: 638 RTVTEWQQQDITEGRLFYRHSGPHSPGPVTDQFTFRVQDNHDPPNQSGLQRFVIRIHPVD 697
Query: 638 DQLPKEAPGVSRHLVVKETEVAYITKKQLHFIDSESYDRELVYTITTPPFFSFSHRHLDA 697
P+ G +VV+E+++ + KK L + D ++ DREL YT+T P + HL A
Sbjct: 698 RLPPELGSGCPLRMVVQESQLTPLRKKWLRYTDLDTDDRELRYTVTQSPTDT-DENHLPA 756
Query: 698 --GKLFMVDSIPKVVKNPTALELRSFTQHAVNYMKVAYMPPMQDIGPHCRDVQFTFSVSN 755
G L + D+ P VV + FTQ +N+ K+AY PP Q++G R QF F V +
Sbjct: 757 PLGTLVLTDN-PSVV-------VTHFTQAQINHHKIAYRPPGQELGVATRVAQFQFQVED 808
Query: 756 QHGGTLHGICFNITILPVDNQVPEAFTNPLKVTEGGQSIISTEHILISDADTKLDNIDLS 815
+ G G F + + PVDNQ PE + E G I+S + ++D DT + +I +
Sbjct: 809 RAGNVAPGT-FTLYLHPVDNQPPEILNTGFTIQEKGHHILSETELHVNDVDTDVAHISFT 867
Query: 816 LRELPLHGRVELNGFPLNSGGTFSWGDLHTLKVRYQHDGTEVLQDDLLLEVTDGTNSAEF 875
L + P HG + ++G L+ GG F D+ +V Y H+G + L D LEV+D +
Sbjct: 868 LTQAPKHGHMRVSGQILHVGGLFHLEDIKQGRVSYAHNGDKSLTDSCSLEVSDRHHVVPI 927
Query: 876 VLHVEVFPVNDEPPVLK---ADLMPVMNCSEGGEVVITSEYIFATDVDSDNLKLMFVIAR 932
L V V PV+DE P+L L ++ E G IT+ I T+ ++D+L L F++
Sbjct: 928 TLRVNVRPVDDEVPILSHPTGTLESYLDVLENGATEITANVIKGTNEETDDLMLTFLLED 987
Query: 933 EPQHGVVRRAGVTVDQFSQRDVISEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVNG 992
P +G + G+ +QF+QRD++ +V Y HT GEIGL+P D+ L +SD + G
Sbjct: 988 PPLYGEILVNGIPAEQFTQRDILEGSVVYTHTSGEIGLLPKADSFNLSLSDMSQEWRIGG 1047
Query: 993 CCYNGPNPSVPLHASFPVYDLNITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATD 1052
G + +T+ PVD+Q P I +G +V EG + +T H+SA D
Sbjct: 1048 NTIQGVT-------------IWVTILPVDSQAPEIFVGEQLIVMEGDKSVITSVHISAED 1094
Query: 1053 PDTAADDLEFVLVSPPQFGYLENILPSVGFEKSNIGISIDSFQWKDMNAFHINYVQSRHL 1112
D+ DD+ +V P GY+ENI P+ G EKS GI+I +F KD+ HINYVQS H
Sbjct: 1095 VDSLNDDILCTIVIQPTSGYVENISPAPGSEKSRAGIAISAFNLKDLRQGHINYVQSVHK 1154
Query: 1113 RIEPTADQFTVYVTDGKHHSLEIPFSIIINPTNDEAPDFVVQNITVCEGQMKELDSSIIS 1172
+EP D+F +DG + S F I+I PTNDE P+ ++ V EG +D+ I++
Sbjct: 1155 GVEPVEDRFVFRCSDGINFSERQFFPIVIIPTNDEQPEMFMREFMVMEGMSLVIDTPILN 1214
Query: 1173 AVDLDIPQDALLFSITQKPRHGLLIDRGFSKDFSENKQPANPHQKHAPVHSFSMELLKTG 1232
A D D+P D L F+ITQ P HG ++++ + V SF+++ +
Sbjct: 1215 AADADVPLDDLTFTITQFPTHGHIMNQLINGT--------------VLVESFTLDQIIES 1260
Query: 1233 MRLTYMHDDSESLADDFTIQLSDGKHKILKTISVEVIPVNDEKPMLSKKAEIAMNMGETR 1292
+ Y HDDSE+ D F I+L+DGKH + KT+ + VIPV+DE P ++ + + +G+T+
Sbjct: 1261 SSIIYEHDDSETQEDSFVIKLTDGKHSVEKTVLIIVIPVDDETPRMTINNGLEIEIGDTK 1320
Query: 1293 IISSAILSAIDEDSPREKIYYVFERLPQNGQLQ-LKIGRDWVPLSPGMKCTQEEVDLNLL 1351
II++ IL A D DS + + Y+ P +G LQ K + ++ GM TQ+EVD NL+
Sbjct: 1321 IINNKILMATDLDSEDKSLVYIIRYGPGHGLLQRRKPTGAFENITLGMNFTQDEVDRNLI 1380
Query: 1352 RYTHTGAMDSQNQDSFTFYLWDGNNRSPALDCQITIKDMEKGDIV---ILTKPLVVSKGD 1408
+Y H G +D F + DG N P +D + + DIV +++K + + +G
Sbjct: 1381 QYVHLG--QEGIRDLIKFDVTDGIN--PLIDRYFYV-SIGSIDIVFPDVISKGVSLKEGG 1435
Query: 1409 RGFLTTTTLLAVDGTDKPEELLYVITSPPRYGQIEYVHYPGVPITNFSQMDVVGQTVCYV 1468
+ LTT L D E L++ IT P G +E PGV IT+F+Q+ + G + Y+
Sbjct: 1436 KVTLTTDLLSTSDLNSPDENLVFTITRAPMRGHLECTDQPGVSITSFTQLQLAGNKIYYI 1495
Query: 1469 HKSKVTVSSDRFRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGLRLAQGAVGLLSPD 1528
H + V D F F +++G F I++ VD PVVT +K L +++ L++P
Sbjct: 1496 HTADDEVKMDSFEFQVTDGRNPVFRTFRISISDVDNKKPVVTIHK-LVVSESENKLITPF 1554
Query: 1529 LLQLTDPDTPAENLTFLLVQLPQHGQLYLWGTGLLQHNFTQQDVDSKNVAYRHSGGDSQT 1588
L + D DTP + L F + Q+P HG L T + FT+QD++ ++Y+H G +S
Sbjct: 1555 ELTVEDRDTPDKLLKFTITQVPIHGHLLFNNTRPVM-VFTKQDLNENLISYKHDGTESSE 1613
Query: 1589 DCFTFMATDGTNQGFIV-NGRVWE--EPVLFTIQVDQLDKTAPRITLLHSPSQVGLLKNG 1645
D F+F TDGT+ F V V+E P + IQV +D + P+I + S + L G
Sbjct: 1614 DSFSFTVTDGTHTDFYVFPDTVFETRRPQVMKIQVLAVDNSVPQIAVNKGASTLRTLATG 1673
Query: 1646 CYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHEKFSQKDLNSKTIL 1705
G ITS++LK D D+ + F + + P+HG+L N G +F+Q D++ I
Sbjct: 1674 HLGFMITSKILKVEDRDSLHISLRFIVTEAPQHGYLLNLDKGNHSITQFTQADIDDMKIC 1733
Query: 1706 YIINPSLEVNSDTVEFQIMDPTGNSATPQILELKWSHIEWSQTEYEVCENVGLLPLEIIR 1765
Y++ SD F + D GN T Q L W+ I + + Y V E+ L + + R
Sbjct: 1734 YVLREGANATSDMFYFAVEDGGGNKLTYQNFRLNWAWISFEKEYYLVNEDSKFLDVVLKR 1793
Query: 1766 RGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQFDPGMSTKMWNIAITYDGLEEDDEVF 1825
RGY +++F+ I +A KDF K +QF+PG + W + I DG E E F
Sbjct: 1794 RGYLGETSFISIGTRDRTAEKDKDFKGKAQKQVQFNPGQTRATWRVRILSDGEHEQSETF 1853
Query: 1826 EVILNSPVNAVLGTKTKAAVKILDSKGGQCHPSYSSNQSKHSTWEKGIWHLLPPGSSSST 1885
+V+L+ PV A L T A V+I+D P+ QSK+S E+ + L P S
Sbjct: 1854 QVVLSEPVLAALEFPTVATVEIVDPGD---EPTVFIPQSKYSV-EEDVGELFIPIRRSGD 1909
Query: 1886 TS 1887
S
Sbjct: 1910 VS 1911
Score = 283 bits (725), Expect = 1e-75
Identities = 341/1429 (23%), Positives = 600/1429 (41%), Gaps = 211/1429 (14%)
Query: 510 FPINVLPKDDSPPFLITNVVIELEEGQTILIQGSMLRASDVDASDDYIFFNITKPPQAGE 569
F + + P D+ PP ++ E+G IL + + L +DVD +I F +T+ P+ G
Sbjct: 818 FTLYLHPVDNQPPEILNTGFTIQEKGHHILSE-TELHVNDVDTDVAHISFTLTQAPKHGH 876
Query: 570 IMKKPGPGLIGYPVHGFLQRDLFNGIIYYRHFGGEIFEDSFQFVLWDSHEPPNLSVPQVA 629
+ G I + F D+ G + Y H G + DS + D H VP
Sbjct: 877 MRVS---GQILHVGGLFHLEDIKQGRVSYAHNGDKSLTDSCSLEVSDRHHV----VPITL 929
Query: 630 TIHITPVDDQLP---KEAPGVSRHLVVKETEVAYITKKQLHFIDSESYDRELVYTITTPP 686
+++ PVDD++P + +L V E IT + + E+ D L + + PP
Sbjct: 930 RVNVRPVDDEVPILSHPTGTLESYLDVLENGATEITANVIKGTNEETDDLMLTFLLEDPP 989
Query: 687 FFSFSHRHLDAGKLFMVDSIPKVVKNPTALELRSFTQHAVNYMKVAYMPPMQDIGPHCRD 746
+ G++ +V+ IP FTQ + V Y +IG +
Sbjct: 990 LY---------GEI-LVNGIPA----------EQFTQRDILEGSVVYTHTSGEIGLLPKA 1029
Query: 747 VQFTFSVSNQH------GGTLHGICFNITILPVDNQVPEAFTNP-LKVTEGGQSIISTEH 799
F S+S+ G T+ G+ +TILPVD+Q PE F L V EG +S+I++ H
Sbjct: 1030 DSFNLSLSDMSQEWRIGGNTIQGVTIWVTILPVDSQAPEIFVGEQLIVMEGDKSVITSVH 1089
Query: 800 ILISDADTKLDNIDLSLRELPLHGRVE----LNGFPLNSGG----TFSWGDL---HTLKV 848
I D D+ D+I ++ P G VE G + G F+ DL H V
Sbjct: 1090 ISAEDVDSLNDDILCTIVIQPTSGYVENISPAPGSEKSRAGIAISAFNLKDLRQGHINYV 1149
Query: 849 RYQHDGTEVLQDDLLLEVTDGTNSAEFVLH-VEVFPVNDEPPVLKADLMPVMNCSEGGEV 907
+ H G E ++D + +DG N +E + + P NDE P + VM EG +
Sbjct: 1150 QSVHKGVEPVEDRFVFRCSDGINFSERQFFPIVIIPTNDEQPEMFMREFMVM---EGMSL 1206
Query: 908 VITSEYIFATDVDSDNLKLMFVIAREPQHGVVRR----AGVTVDQFSQRDVI-SEAVTYK 962
VI + + A D D L F I + P HG + V V+ F+ +I S ++ Y+
Sbjct: 1207 VIDTPILNAADADVPLDDLTFTITQFPTHGHIMNQLINGTVLVESFTLDQIIESSSIIYE 1266
Query: 963 HTGGEIGLMPCFDTITLVVSDGEAGPFVNGCCYNGPNPSVPLHASFPVYDLNITVYPVDN 1022
H E D+ + ++DG+ H+ + I V PVD+
Sbjct: 1267 HDDSETQE----DSFVIKLTDGK-------------------HSVEKT--VLIIVIPVDD 1301
Query: 1023 QPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSVGF 1082
+ P + I ++ G + + L ATD D+ L +++ P G L+ P+ F
Sbjct: 1302 ETPRMTINNGLEIEIGDTKIINNKILMATDLDSEDKSLVYIIRYGPGHGLLQRRKPTGAF 1361
Query: 1083 EKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSIIIN 1142
E +G++ F +++ I YV HL E D VTDG + ++ F + I
Sbjct: 1362 ENITLGMN---FTQDEVDRNLIQYV---HLGQEGIRDLIKFDVTDGINPLIDRYFYVSIG 1415
Query: 1143 PTNDEAPDFVVQNITVCEGQMKELDSSIISAVDLDIPQDALLFSITQKPRHGLLIDRGFS 1202
+ PD + + +++ EG L + ++S DL+ P + L+F+IT+ P G L
Sbjct: 1416 SIDIVFPDVISKGVSLKEGGKVTLTTDLLSTSDLNSPDENLVFTITRAPMRGHL------ 1469
Query: 1203 KDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHD-DSESLADDFTIQLSDGKHKIL 1261
Q + SF+ +L G ++ Y+H D E D F Q++DG++ +
Sbjct: 1470 ---------ECTDQPGVSITSFT-QLQLAGNKIYYIHTADDEVKMDSFEFQVTDGRNPVF 1519
Query: 1262 KTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQN 1321
+T + + V+++KP+++ ++ ++ E ++I+ L+ D D+P + + + ++P +
Sbjct: 1520 RTFRISISDVDNKKPVVTIH-KLVVSESENKLITPFELTVEDRDTPDKLLKFTITQVPIH 1578
Query: 1322 GQLQLKIGRDWVPLSPGMKCTQEEVDLNLLRYTHTGAMDSQNQDSFTFYLWDGNN----- 1376
G L R P M T+++++ NL+ Y H G S+ DSF+F + DG +
Sbjct: 1579 GHLLFNNTR------PVMVFTKQDLNENLISYKHDGTESSE--DSFSFTVTDGTHTDFYV 1630
Query: 1377 ---------RSPALDCQITIKDMEKGDIVI---LTKPLVVSKGDRGFLTTTTLLAVDGTD 1424
R + Q+ D I + + ++ G GF+ T+ +L V+ D
Sbjct: 1631 FPDTVFETRRPQVMKIQVLAVDNSVPQIAVNKGASTLRTLATGHLGFMITSKILKVEDRD 1690
Query: 1425 KPE-ELLYVITSPPRYGQIEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFI 1483
L +++T P++G + + IT F+Q D+ +CYV + +SD F F
Sbjct: 1691 SLHISLRFIVTEAPQHGYLLNLDKGNHSITQFTQADIDDMKICYVLREGANATSDMFYFA 1750
Query: 1484 ISNGLRTEHGVFEITLETVDRALPVVTRNKGLRLAQGAVGLLSPDLLQLTDPDTPAENLT 1543
+ +G G ++T + ++ K L E+
Sbjct: 1751 VEDG-----GGNKLTYQNFRLNWAWISFEKEYYLVN--------------------EDSK 1785
Query: 1544 FLLVQLPQHGQLYLWGTGLL----QHNFTQQDVDSKNVAYRH---SGGDSQTDCFTFMAT 1596
FL V L + G YL T + + ++D D K A + + G ++ + +
Sbjct: 1786 FLDVVLKRRG--YLGETSFISIGTRDRTAEKDKDFKGKAQKQVQFNPGQTRATWRVRILS 1843
Query: 1597 DGTNQGFIVNGRVWEEPVLFTIQ---------VDQLDKTAPRITLLHSPSQVGLLKNGCY 1647
DG ++ V EPVL ++ VD D+ P + + S V +
Sbjct: 1844 DGEHEQSETFQVVLSEPVLAALEFPTVATVEIVDPGDE--PTVFIPQSKYSV---EEDVG 1898
Query: 1648 GIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTG--EFIHE--------KFSQK 1697
++I ++ S +++ ++ QG G + + ++I +F +
Sbjct: 1899 ELFIP---IRRSGDVSQELMVVCYTQQGTATGTVPTSVLSYSDYISRPEDHTSVVRFDKD 1955
Query: 1698 DLNSKTILYIINPSLEVNSDTVEFQIMDPTGNSATPQILELKWSHIE---------WSQT 1748
+ + II+ SL +T + P G + + + + +
Sbjct: 1956 EREKLCRIVIIDDSLYEEEETFHVLLSMPMGGRIGSEFPGAQVTIVPDKDDEPIFYFGDV 2015
Query: 1749 EYEVCENVGLLPLEIIRRGYSMD-SAFVGI---KVNQVSAAVGKDFTVIPSKLIQFDPGM 1804
EY V E+ G + +++ R G + S+ V + K + SA G D+ I S+ + F PG+
Sbjct: 2016 EYSVDESAGYVEVQVWRTGTDLSKSSSVTVRSRKTDPPSADAGTDYVGI-SRNLDFAPGV 2074
Query: 1805 STKMWNIAITYDGLE---EDDEVFEVILNSPVNAVLGTKTKAAVKILDS 1850
+ + + I D + E E FE++L P+NA LG +KA V I DS
Sbjct: 2075 NMQPVRVVILDDLGQPALEGIEKFELVLRMPMNAALGEPSKATVSINDS 2123
Score = 42.0 bits (97), Expect = 0.007
Identities = 28/124 (22%), Positives = 58/124 (46%), Gaps = 1/124 (0%)
Query: 1738 LKWSHIEWSQTEYEVCENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKL 1797
+K+ ++S TE + ++ + +IR+G + + V + SA G+D+ + S+
Sbjct: 2251 IKFGETKFSVTEPKEPGESVVIRIPVIRQGDTSKVSIVRVHTKDGSATSGEDYHPV-SEE 2309
Query: 1798 IQFDPGMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTKTKAAVKILDSKGGQCHP 1857
I+F G + + I +T+DG+ E E F V L N + + A+ ++
Sbjct: 2310 IEFKEGETQHVVEIEVTFDGVREMREAFTVHLKPDENMIAEMQLTKAIVYIEEMSSMADV 2369
Query: 1858 SYSS 1861
++ S
Sbjct: 2370 TFPS 2373
>gi|169167211 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
sapiens]
Length = 2139
Score = 852 bits (2200), Expect = 0.0
Identities = 608/1897 (32%), Positives = 913/1897 (48%), Gaps = 145/1897 (7%)
Query: 23 PTFISINRGVRVMKGHSAFLSGDDLKFAIPKEKDACKVEVVMNEPITQRVGKLTPQVFDC 82
P+ + N G+RV G S +L D L+ + + + EV + + + + G L+P+ F C
Sbjct: 60 PSVLIANPGLRVPLGRSLWL--DPLRDLVIGVQPGDRCEVTVLDALPRLKGALSPRRFPC 117
Query: 83 HFLPNEVKYVHNGCPILDEDTVKLRLYRFTERDTFIETFILWVYLLEPDCNIIHMSNNVL 142
F P +V+Y H G V L+L T + F L V L+ ++ N L
Sbjct: 118 TFGPRQVQYTHFGSHSPGRARVLLQLRYDAPTHTLVLPFTLAVDLVFSQLELV-TRNRPL 176
Query: 143 EVPEFNGLSQAIDKNLLRFDYDRMASLECTVSLDTARTRLPAHGQMVLGEPRPEEPRGDQ 202
V + S+AID+ +L F ASL+ + T R RL P P E D
Sbjct: 177 VVEKLRSWSRAIDRRVLDF-----ASLKSGATA-TRRCRLT---------PLPHE---DG 218
Query: 203 PHSFFPESQLRAKLKCPGGSCTPGLKKIGSLKVSCEEFLLMGLRYQHLDPPSPNIDYISI 262
P + P G V CE FL G+RYQH SPN DY+ +
Sbjct: 219 PLPKYGRLVDAVGAPLPRGK-----------GVDCEAFLRAGVRYQHTATSSPNRDYVPM 267
Query: 263 QLDLT-----DTRSKIVYKSESAWLPVYIRAGIPNQIPKAAFMAVFILEVDQFILTSLTT 317
++L D S V E L V IR G N P+ +FMA ++EVD +LT+LT
Sbjct: 268 MVELLGPEGQDAGSAGVLVREHFQLLVRIRGGAENTPPRPSFMATMMMEVDPLVLTALTP 327
Query: 318 SVLDCEEDETPKPLLVFNITKAPL--------QGYVTHLLDHTR-PISSFTWKDLSDMQI 368
L E+ E+ LVFNI AP QGYV D P+S FT ++L +++I
Sbjct: 328 DALAAEDVESDPGDLVFNILNAPTHPPGHPGQQGYVVSTDDPLGLPVSFFTQQELRELKI 387
Query: 369 AYQPP-NSSHSERRHDEVELEVYDFFFERSAPMTVHISIRTADTNAPRVSWNTGLSLLEG 427
AYQPP +SH ER ++ELEV D S P +++++ +T P S N GL L EG
Sbjct: 388 AYQPPAENSHGERLF-QLELEVVDGDGAASDPFAFMVTVKSMNTLVPVASHNRGLVLFEG 446
Query: 428 QSRAIT-WEQFQVVDNDDIGAVRLVTVGGLQHGWLTLRGGKGFL--FTVADLQAGVVRYH 484
QSR ++ + D D++ V++ V GL+HG L + G FT ADL AG V Y
Sbjct: 447 QSRPLSSTHSIPISDKDNLEEVKMAAVRGLRHGQLVVFGAPAGCKYFTPADLAAGRVVYQ 506
Query: 485 HDDSDSTKDFVVFRIFDGHHSIRHKFPINVLPKDDSPPFLITNVVIELEEGQTILIQGSM 544
HD S++ D ++FR+ DGHH + FP+ +LP DD PP + TN + L EGQ + I +
Sbjct: 507 HDGSNTYSDNIIFRMEDGHHQVDFLFPLTILPVDDEPPMVNTNTGLSLTEGQVVQISPFV 566
Query: 545 LRASDVDASDDYIFFNITKPPQAGEIMKK-----PGP----------------------- 576
L A+D+D+ D I F + P G + PG
Sbjct: 567 LSATDIDSEDSTIHFVLENQPLKGNEEEPQWELAPGSSHSGHYLGDLLLQQAELPLSTED 626
Query: 577 ---------GLIGYPVHGFLQRDLFNGIIYYRHFGGEIFED---SFQFVLWDSHEPPNLS 624
GL V +LQRD+ G ++YRH G + F + D H+PPNLS
Sbjct: 627 EDWHYMEKEGLYEKVVTEWLQRDIMEGRLFYRHLGPHSPQSVMVQLAFHVQDDHDPPNLS 686
Query: 625 VPQVATIHITPVDDQLPKEAPGVSRHLVVKETEVAYITKKQLHFIDSESYDRELVYTITT 684
+ TI + PVD P+ PG + + V+E ++ + K L +ID +S D+ L YT+ T
Sbjct: 687 KQHIFTIKVQPVDILSPQLYPGTTLEMTVQEYQLTHFQKNFLRYIDQDSDDQNLWYTLLT 746
Query: 685 PPFFSFSHRHLDAGKLFMVDSIPKVVKNPTALELRSFTQHAVNYMKVAYMPPMQDIGPHC 744
P + + + AG++ + DS ++ + FTQ VN KVAY PP Q +G
Sbjct: 747 LPTDTDGNHQVRAGEIVLTDSPDTLIMH--------FTQAQVNQHKVAYQPP-QKLGIAP 797
Query: 745 RDVQFTFSVSNQHGGTLHGICFNITILPVDNQVPEAFTNPLKVTEGGQSIISTEHILISD 804
R VQFT+ V + G ++ G F + + PVDNQ PE + EGG +S+ + ++D
Sbjct: 798 RVVQFTYQVEDAAGNSVPGT-FTLFLQPVDNQPPEVTNRGFAILEGGSFNLSSNELHVTD 856
Query: 805 ADTKLDNIDLSLRELPLHGRVELNGFPLNSGGTFSWGDLHTLKVRYQHDGTEVLQDDLL- 863
DT +D I L P HG ++ + G +F D+ V YQH + D
Sbjct: 857 PDTDIDQIVFILVRGPQHGHLQYFKRCMVPGESFMQADVINGSVSYQHGRDQTTTSDTFH 916
Query: 864 LEVTDGTNSAEFVLHVEVFP--VNDEPPVL--KADLMPV-MNCSEGGEVVITSEYIFATD 918
LEV+DG + + + V P N P + + L+ V ++ E IT I
Sbjct: 917 LEVSDGVHHIPITIPISVHPNVANRSPRISLRSSSLLDVSIDVLENKATEITMGVIHGKR 976
Query: 919 VDSDNLKLMFVIAREPQHGVVRRAGVTVDQFSQRDVISEAVTYKHTGGEIGLMPCFDTIT 978
D +L L F++ P+ G + G+ ++F+Q D+I+ V Y HT GE+G D +
Sbjct: 977 KDVGDLMLSFIVKDSPKLGTILVNGLPTERFTQEDLINGRVAYAHTAGEVGFQKQHDAFS 1036
Query: 979 LVVSDGEAGPFVNGCCYNGPNPSVPLHASFPVYDLNITVYPVDNQPPSIAIGPVFVVDEG 1038
L++S ++ +V G ++ + +TV PVDN P + +G F+V EG
Sbjct: 1037 LILSK-DSYQWVVG------------NSIIEKVQVQVTVLPVDNVGPKVLVGESFIVYEG 1083
Query: 1039 CSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSVGFEKSNIGISIDSFQWKD 1098
+LT+ HL D DT D+L + S P GYLE I + G + S G I +F +D
Sbjct: 1084 EKNSLTLQHLHVEDVDTHQDELLCTVTSQPASGYLEKIASAPGSKMSQSGSPISAFSLRD 1143
Query: 1099 MNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSIIINPTNDEAPDFVVQNITV 1158
+ HINYVQS H +EP DQFT Y +DG + S + F III PTNDE P V
Sbjct: 1144 IQVRHINYVQSIHKGVEPQEDQFTFYCSDGINFSPNVFFPIIILPTNDEQPKLFAHEFKV 1203
Query: 1159 CEGQMKELDSSIISAVDLDIPQDALLFSITQKPRHGLLIDRGFSKDFSENKQPANPHQKH 1218
EG +D+ +++ D D+P + L F +T PRHG +I +Q A Q
Sbjct: 1204 LEGMSLVIDTQLLNGADADLPPNELHFQLTALPRHGRII-----------QQLATGSQ-- 1250
Query: 1219 APVHSFSMELLKTGMRLTYMHDDSESLADDFTIQLSDGKHKILKTISVEVIPVNDEKPML 1278
P+HSF+++ ++ + Y HDDSE+ D F + LSDGKH + + + V V+DE P L
Sbjct: 1251 -PIHSFTLKEIQEASTIVYEHDDSETKEDSFEVWLSDGKHTTHRKVPIVVTLVDDETPHL 1309
Query: 1279 SKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQNGQLQ-LKIGRDWV--PL 1335
+ + + G + II++ IL A D DS + + +V PQ G LQ L+ R V L
Sbjct: 1310 TVNNGLKVEKGHSEIITNRILKATDLDSDDKSLSFVLHSGPQQGLLQRLRKPRGEVRNNL 1369
Query: 1336 SPGMKCTQEEVDLNLLRYTHTGAMDSQNQDSFTFYLWDGNNRSPALDCQITIKDMEKGDI 1395
+ GM TQ+E++ L+ Y HTG D F + DG N +TI +++
Sbjct: 1370 TLGMNFTQDEINRGLICYIHTG--QEGIVDIIKFDVTDGVNTLTDHYFYVTIGNLDSVFP 1427
Query: 1396 VILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYGQIEYVHYPGVPITNF 1455
+++K + + +G R L T LL + +E + IT P G +E Y G PI +F
Sbjct: 1428 EVISKRITLIEGARVTL-TNNLLTNSDINSSDEHHFSITRAPSLGHLESSDYAGEPIASF 1486
Query: 1456 SQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGL 1515
+Q+ + + YVH S D F F + L F I + VD P++T ++ L
Sbjct: 1487 TQLQLASNKISYVHTSNDEKKMDSFEFQVIGELYPVFRTFRIFITDVDNKKPILTIHR-L 1545
Query: 1516 RLAQGAVGLLSPDLLQLTDPDTPAENLTFLLVQLPQHGQLYLWGTGLLQHNFTQQDVDSK 1575
L + L++ L + D DTP + + F + Q+P HG++ G+ + FT+QD++
Sbjct: 1546 TLQKEDSQLITLLELTVEDSDTPDDLILFTITQVPMHGKILYNGSRPVT-TFTKQDLNKN 1604
Query: 1576 NVAYRHSGGDSQTDCFTFMATDGTNQGFIV---NGRVWEEPVLFTIQVDQLDKTAPRITL 1632
++Y+H G ++ D F+ TDGT+ F V +P + +Q+ LD P+IT
Sbjct: 1605 LISYKHDGSETTEDSFSLTVTDGTHTDFYVLPDTALATHKPQVMRVQIRSLDNRLPQITT 1664
Query: 1633 LHSPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHE 1692
+ L G G ITS+ LKA D D+ + +K+ +GP+HG + T G
Sbjct: 1665 NRGAPALKRLHTGHMGFLITSKSLKAEDQDSPHRLLKYKVTRGPEHGFIIKTGLGNQSTR 1724
Query: 1693 KFSQKDLNSKTILYIINPSLEVNSDTVEFQIMDPTGNSATPQILELKWSHIEWSQTEYEV 1752
F+Q D++ I Y++N + D F + D GN T Q L W+ I + Y V
Sbjct: 1725 VFTQADIDEMKISYVLNEGSNASKDIFYFSVEDNGGNKLTNQPFHLNWAWICLEKEYYIV 1784
Query: 1753 CENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQFDPGMSTKMWNIA 1812
E+ L + + RRGY +++F+ I +A KDF +K IQF+PG +T W +
Sbjct: 1785 DEDSTFLEVTLTRRGYLGETSFISIGTKDETAKKDKDFKWKTNKQIQFNPGQTTATWRVR 1844
Query: 1813 ITYDGLEEDDEVFEVILNSPVNAVLGTKTKAAVKILD 1849
I D E E F++IL+ P+ AVL A V+I+D
Sbjct: 1845 IIPDNEYETSETFQIILSEPLMAVLEFPEMATVEIVD 1881
Score = 215 bits (548), Expect = 3e-55
Identities = 352/1512 (23%), Positives = 596/1512 (39%), Gaps = 237/1512 (15%)
Query: 475 DLQAGVVRYHHDDSDSTKDFVV---FRIFDGHH----SIRHKFPINVLPKDDSPPFLITN 527
D+ G + Y H S + +V F + D H S +H F I V P D P L
Sbjct: 649 DIMEGRLFYRHLGPHSPQSVMVQLAFHVQDDHDPPNLSKQHIFTIKVQPVDILSPQLYPG 708
Query: 528 VVIEL--EEGQTILIQGSMLRASDVDASDDYIFFNITKPP---------QAGEIMKKPGP 576
+E+ +E Q Q + LR D D+ D +++ + P +AGEI+ P
Sbjct: 709 TTLEMTVQEYQLTHFQKNFLRYIDQDSDDQNLWYTLLTLPTDTDGNHQVRAGEIVLTDSP 768
Query: 577 GLIGYPVHGFLQRDLFNGIIYYRH-----FGGEIFEDSFQFVLWDSHEPPNLSVPQVATI 631
+ + F Q + + Y+ + + ++Q + SVP T+
Sbjct: 769 DTL---IMHFTQAQVNQHKVAYQPPQKLGIAPRVVQFTYQV-----EDAAGNSVPGTFTL 820
Query: 632 HITPVDDQLPKEAPGVSRHLVVKETEVAYITKKQLHFIDSESYDRELVYTITTPPFFSFS 691
+ PVD+Q P+ +R + E ++ +LH D ++ ++V+ + P
Sbjct: 821 FLQPVDNQPPEVT---NRGFAILEGGSFNLSSNELHVTDPDTDIDQIVFILVRGP----Q 873
Query: 692 HRHLDAGKLFMVDSIPKVVKNPTALELRSFTQHAVNYMKVAYMPPMQDIGPHCRD---VQ 748
H HL K MV SF Q V V+Y H RD
Sbjct: 874 HGHLQYFKRCMVPG-------------ESFMQADVINGSVSYQ--------HGRDQTTTS 912
Query: 749 FTFSVSNQHGGTLHGICFNITILP-VDNQVPEAFTNPLKVTEGGQSII---STEHILISD 804
TF + G I I++ P V N+ P + + ++ +TE +
Sbjct: 913 DTFHLEVSDGVHHIPITIPISVHPNVANRSPRISLRSSSLLDVSIDVLENKATEITMGVI 972
Query: 805 ADTKLDNIDLSL----RELPLHGRVELNGFPLNSGGTFSWGDLHTLKVRYQHDGTEV--- 857
+ D DL L ++ P G + +NG P F+ DL +V Y H EV
Sbjct: 973 HGKRKDVGDLMLSFIVKDSPKLGTILVNGLPTER---FTQEDLINGRVAYAHTAGEVGFQ 1029
Query: 858 ---------LQDDLLLEVTDGTNSAEFVLHVEVFPV-NDEPPVLKADLMPVMNCSEGGEV 907
L D V + + + V V PV N P VL + V EG +
Sbjct: 1030 KQHDAFSLILSKDSYQWVVGNSIIEKVQVQVTVLPVDNVGPKVLVGESFIVY---EGEKN 1086
Query: 908 VITSEYIFATDVDSDNLKLMFVIAREPQHGVVRR-----------AGVTVDQFSQRDVIS 956
+T +++ DVD+ +L+ + +P G + + +G + FS RD+
Sbjct: 1087 SLTLQHLHVEDVDTHQDELLCTVTSQPASGYLEKIASAPGSKMSQSGSPISAFSLRDIQV 1146
Query: 957 EAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVNGCCYNGPNPSVPLHASFPVYDLNIT 1016
+ Y + + G+ P D T SDG +N PN P I
Sbjct: 1147 RHINYVQSIHK-GVEPQEDQFTFYCSDG-----INF----SPNVFFP-----------II 1185
Query: 1017 VYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENI 1076
+ P +++ P + F V EG S + L+ D D ++L F L + P+ G +
Sbjct: 1186 ILPTNDEQPKL-FAHEFKVLEGMSLVIDTQLLNGADADLPPNELHFQLTALPRHGRIIQQ 1244
Query: 1077 LPSVGFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHS-LEI 1135
L + G + I SF K++ + + H E D F V+++DGKH + ++
Sbjct: 1245 L-ATGSQP------IHSFTLKEIQ--EASTIVYEHDDSETKEDSFEVWLSDGKHTTHRKV 1295
Query: 1136 PFSIIINPTNDEAPDFVVQN-ITVCEGQMKELDSSIISAVDLDIPQDALLFSITQKPRHG 1194
P I++ +DE P V N + V +G + + + I+ A DLD +L F + P+ G
Sbjct: 1296 P--IVVTLVDDETPHLTVNNGLKVEKGHSEIITNRILKATDLDSDDKSLSFVLHSGPQQG 1353
Query: 1195 LLIDRGFSKDFSENKQPANPHQKHAPVH-SFSMELLKTGMRLTYMHDDSESLADDFTIQL 1253
LL ++P + + + +F+ + + G+ + Y+H E + D +
Sbjct: 1354 LL---------QRLRKPRGEVRNNLTLGMNFTQDEINRGL-ICYIHTGQEGIVDIIKFDV 1403
Query: 1254 SDGKHKILKTISVEVIPVNDE--KPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKI 1311
+DG + + I D ++SK+ I + G +++ +L+ D +S E
Sbjct: 1404 TDGVNTLTDHYFYVTIGNLDSVFPEVISKR--ITLIEGARVTLTNNLLTNSDINSSDEH- 1460
Query: 1312 YYVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNLLRYTHTGAMDSQNQDSFTFYL 1371
++ R P G L+ D+ P TQ ++ N + Y HT + D + DSF F +
Sbjct: 1461 HFSITRAPSLGHLE---SSDYAG-EPIASFTQLQLASNKISYVHT-SNDEKKMDSFEFQV 1515
Query: 1372 WDGNNRSPALDCQITIKDMEKGDIVILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEEL-L 1430
G +I I D++ ++ L + K D +T L V+ +D P++L L
Sbjct: 1516 I-GELYPVFRTFRIFITDVDNKKPILTIHRLTLQKEDSQLITLLEL-TVEDSDTPDDLIL 1573
Query: 1431 YVITSPPRYGQIEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRT 1490
+ IT P +G+I Y P+T F++ D+ + Y H T + D F +++G T
Sbjct: 1574 FTITQVPMHGKILY--NGSRPVTTFTKQDLNKNLISYKHDGSET-TEDSFSLTVTDGTHT 1630
Query: 1491 EH-------------GVFEITLETVDRALPVVTRNKGL----RLAQGAVG-LLSPDLLQL 1532
+ V + + ++D LP +T N+G RL G +G L++ L+
Sbjct: 1631 DFYVLPDTALATHKPQVMRVQIRSLDNRLPQITTNRGAPALKRLHTGHMGFLITSKSLKA 1690
Query: 1533 TDPDTPAENLTFLLVQLPQHGQLYLWGTGLLQHN-FTQQDVDSKNVAY-RHSGGDSQTDC 1590
D D+P L + + + P+HG + G G FTQ D+D ++Y + G ++ D
Sbjct: 1691 EDQDSPHRLLKYKVTRGPEHGFIIKTGLGNQSTRVFTQADIDEMKISYVLNEGSNASKDI 1750
Query: 1591 FTFMATDG-----TNQGFIVNGR-VWEEPVLFTIQVDQLDKTAPRITLLHSPSQVGLLKN 1644
F F D TNQ F +N + E + + D T L +V L +
Sbjct: 1751 FYFSVEDNGGNKLTNQPFHLNWAWICLEKEYYIVDEDS--------TFL----EVTLTRR 1798
Query: 1645 GCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHEKFSQKDLNSKTI 1704
G G TS + + +T FK + TT + + +
Sbjct: 1799 GYLGE--TSFISIGTKDETAKKDKDFKWKTNKQIQFNPGQTTATWRVRIIPDNEYETSET 1856
Query: 1705 LYII--NPSLEVNS--DTVEFQIMDPTGNSATPQILELKWSHIEWSQTEYEVCENVGLLP 1760
II P + V + +I+DP G+ +T I E EY++ E++G L
Sbjct: 1857 FQIILSEPLMAVLEFPEMATVEIVDP-GDESTVYIPE----------AEYKIEEDIGELL 1905
Query: 1761 LEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPS----------KLIQFDPGMSTKMWN 1810
+ + R G + V Q SA TV+ S ++ FD + K
Sbjct: 1906 IPVRRSGDASQELIVICSTRQGSATGTISSTVLFSDYISRPEDHTSILHFDKNETQKTCQ 1965
Query: 1811 IAITYDGLEEDDEVFEVILNSPVNAVLGTK---TKAAV-------KILDSKGGQCHPSYS 1860
+ I D L E++E F V L PV LG + TK + +L + H + S
Sbjct: 1966 VLIIDDSLYEEEESFSVSLRLPVGGQLGARFPTTKVTILADRYDEPVLHFGDAEYHVNES 2025
Query: 1861 SNQSKHSTWEKG 1872
+ + W +G
Sbjct: 2026 ARYVEVCVWRRG 2037
Score = 208 bits (529), Expect = 5e-53
Identities = 315/1437 (21%), Positives = 567/1437 (39%), Gaps = 212/1437 (14%)
Query: 504 HSIRHKFPINVLPKDDSPPFLITNVVIELEEGQTILIQGSMLRASDVDASDDYIFFNITK 563
+S+ F + + P D+ PP +TN + EG + + + L +D D D I F + +
Sbjct: 812 NSVPGTFTLFLQPVDNQPPE-VTNRGFAILEGGSFNLSSNELHVTDPDTDIDQIVFILVR 870
Query: 564 PPQAGEIMKKPGPGLIGYPVHGFLQRDLFNGIIYYRHFGGEIF-EDSFQFVLWDSHEPPN 622
PQ G + + P F+Q D+ NG + Y+H + D+F + D
Sbjct: 871 GPQHGHLQYFKRCMV---PGESFMQADVINGSVSYQHGRDQTTTSDTFHLEVSDGVHHIP 927
Query: 623 LSVPQVATIHITP-VDDQLPKEAPGVSRHLVVK----ETEVAYITKKQLHFIDSESYDRE 677
+++P I + P V ++ P+ + S L V E + IT +H + D
Sbjct: 928 ITIP----ISVHPNVANRSPRISLRSSSLLDVSIDVLENKATEITMGVIHGKRKDVGDLM 983
Query: 678 LVYTITTPPFFSFSHRHLDAGKLFMVDSIPKVVKNPTALELRSFTQHAVNYMKVAYMPPM 737
L + + P +V+ +P FTQ + +VAY
Sbjct: 984 LSFIVKDSPKLG----------TILVNGLPT----------ERFTQEDLINGRVAYAHTA 1023
Query: 738 QDIGPHCRDVQFTFSVSNQH------GGTLHGICFNITILPVDNQVPEAFTNP-LKVTEG 790
++G + F+ +S + + +T+LPVDN P+ V EG
Sbjct: 1024 GEVGFQKQHDAFSLILSKDSYQWVVGNSIIEKVQVQVTVLPVDNVGPKVLVGESFIVYEG 1083
Query: 791 GQSIISTEHILISDADTKLDNIDLSLRELPLHGRVE----LNGFPLNSGGT----FSWGD 842
++ ++ +H+ + D DT D + ++ P G +E G ++ G+ FS D
Sbjct: 1084 EKNSLTLQHLHVEDVDTHQDELLCTVTSQPASGYLEKIASAPGSKMSQSGSPISAFSLRD 1143
Query: 843 LHTLKVRYQ---HDGTEVLQDDLLLEVTDGTN-SAEFVLHVEVFPVNDEPPVLKADLMPV 898
+ + Y H G E +D +DG N S + + P NDE P L A V
Sbjct: 1144 IQVRHINYVQSIHKGVEPQEDQFTFYCSDGINFSPNVFFPIIILPTNDEQPKLFAHEFKV 1203
Query: 899 MNCSEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHGVVRRAGVTVDQ----FSQRDV 954
+ EG +VI ++ + D D +L F + P+HG + + T Q F+ +++
Sbjct: 1204 L---EGMSLVIDTQLLNGADADLPPNELHFQLTALPRHGRIIQQLATGSQPIHSFTLKEI 1260
Query: 955 I-SEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVNGCCYNGPNPSVPLHASFPVYDL 1013
+ + Y+H E D+ + +SDG+ H P
Sbjct: 1261 QEASTIVYEHDDSETKE----DSFEVWLSDGKH----------------TTHRKVP---- 1296
Query: 1014 NITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYL 1073
I V VD++ P + + V++G S +T L ATD D+ L FVL S PQ G L
Sbjct: 1297 -IVVTLVDDETPHLTVNNGLKVEKGHSEIITNRILKATDLDSDDKSLSFVLHSGPQQGLL 1355
Query: 1074 ENILPSVGFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSL 1133
+ + G ++N+ + ++ F ++N I Y+ H E D VTDG +
Sbjct: 1356 QRLRKPRGEVRNNLTLGMN-FTQDEINRGLICYI---HTGQEGIVDIIKFDVTDGVNTLT 1411
Query: 1134 EIPFSIIINPTNDEAPDFVVQNITVCEGQMKELDSSIISAVDLDIPQDALLFSITQKPRH 1193
+ F + I + P+ + + IT+ EG L +++++ D++ D FSIT+ P
Sbjct: 1412 DHYFYVTIGNLDSVFPEVISKRITLIEGARVTLTNNLLTNSDIN-SSDEHHFSITRAPSL 1470
Query: 1194 GLLIDRGFSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMH-DDSESLADDFTIQ 1252
G L ++ + P+ SF+ +L +++Y+H + E D F Q
Sbjct: 1471 GHLESSDYAGE---------------PIASFT-QLQLASNKISYVHTSNDEKKMDSFEFQ 1514
Query: 1253 LSDGKHKILKTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIY 1312
+ + + +T + + V+++KP+L+ + + ++++I+ L+ D D+P + I
Sbjct: 1515 VIGELYPVFRTFRIFITDVDNKKPILTIH-RLTLQKEDSQLITLLELTVEDSDTPDDLIL 1573
Query: 1313 YVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNLLRYTHTGAMDSQNQDSFTFYLW 1372
+ ++P +G++ R P T+++++ NL+ Y H G+ +DSF+ +
Sbjct: 1574 FTITQVPMHGKILYNGSR------PVTTFTKQDLNKNLISYKHDGS--ETTEDSFSLTVT 1625
Query: 1373 DGNN--------------RSPALDCQITIKDMEKGDIVILTKPLVVSK---GDRGFLTTT 1415
DG + + + QI D I + + G GFL T+
Sbjct: 1626 DGTHTDFYVLPDTALATHKPQVMRVQIRSLDNRLPQITTNRGAPALKRLHTGHMGFLITS 1685
Query: 1416 TLLAVDGTDKPEELL-YVITSPPRYGQIEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVT 1474
L + D P LL Y +T P +G I F+Q D+ + Y
Sbjct: 1686 KSLKAEDQDSPHRLLKYKVTRGPEHGFIIKTGLGNQSTRVFTQADIDEMKISY------- 1738
Query: 1475 VSSDRFRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGLRLAQGAVGLLSPDLLQLTD 1534
+++ G +F ++E N G +L L + +
Sbjct: 1739 --------VLNEGSNASKDIFYFSVED----------NGGNKLTNQPFHLNWAWICLEKE 1780
Query: 1535 PDTPAENLTFLLVQLPQHGQLYLWGTGLLQHNFTQQDVDSKNVAYRHSGGDSQTDCFTFM 1594
E+ TFL V L + G YL T + T+ + K+ ++ ++ F
Sbjct: 1781 YYIVDEDSTFLEVTLTRRG--YLGETSFISIG-TKDETAKKDKDFKWK--TNKQIQFNPG 1835
Query: 1595 ATDGTNQGFIVNGRVWEEPVLFTIQVDQLDKTAPRITLLHSPSQ--VGLLKNGCYG-IYI 1651
T T + I+ +E F I + + P + +L P V ++ G +YI
Sbjct: 1836 QTTATWRVRIIPDNEYETSETFQIILSE-----PLMAVLEFPEMATVEIVDPGDESTVYI 1890
Query: 1652 TSRVLKASDP------------DTEDDQIIF-KILQGPKHGHLENTTT-GEFIHEK---- 1693
K + D + I+ QG G + +T ++I
Sbjct: 1891 PEAEYKIEEDIGELLIPVRRSGDASQELIVICSTRQGSATGTISSTVLFSDYISRPEDHT 1950
Query: 1694 ----FSQKDLNSKTILYIINPSLEVNSDTVEFQIMDPTGNSATPQ-------ILELKWSH 1742
F + + + II+ SL ++ + P G + IL ++
Sbjct: 1951 SILHFDKNETQKTCQVLIIDDSLYEEEESFSVSLRLPVGGQLGARFPTTKVTILADRYDE 2010
Query: 1743 --IEWSQTEYEVCENVGLLPLEIIRRGYSMDS----AFVGIKVNQVSAAVGKDFTVIPSK 1796
+ + EY V E+ + + + RRG + A K Q SA G D+ I S+
Sbjct: 2011 PVLHFGDAEYHVNESARYVEVCVWRRGTDLSQPSSIAVRSRKSEQESAEAGTDYVGI-SR 2069
Query: 1797 LIQFDPGMSTKMWNIAITYDGLE---EDDEVFEVILNSPVNAVLGTKTKAAVKILDS 1850
+ F PG+ + + + I D + E E FE++L P+ AVLG K + I D+
Sbjct: 2070 NLDFAPGVRMQTFQVTILDDLGQPTLEGPEKFELLLQMPMGAVLGEPNKTTIFIEDT 2126
>gi|169166904 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
sapiens]
Length = 2139
Score = 852 bits (2200), Expect = 0.0
Identities = 608/1897 (32%), Positives = 913/1897 (48%), Gaps = 145/1897 (7%)
Query: 23 PTFISINRGVRVMKGHSAFLSGDDLKFAIPKEKDACKVEVVMNEPITQRVGKLTPQVFDC 82
P+ + N G+RV G S +L D L+ + + + EV + + + + G L+P+ F C
Sbjct: 60 PSVLIANPGLRVPLGRSLWL--DPLRDLVIGVQPGDRCEVTVLDALPRLKGALSPRRFPC 117
Query: 83 HFLPNEVKYVHNGCPILDEDTVKLRLYRFTERDTFIETFILWVYLLEPDCNIIHMSNNVL 142
F P +V+Y H G V L+L T + F L V L+ ++ N L
Sbjct: 118 TFGPRQVQYTHFGSHSPGRARVLLQLRYDAPTHTLVLPFTLAVDLVFSQLELV-TRNRPL 176
Query: 143 EVPEFNGLSQAIDKNLLRFDYDRMASLECTVSLDTARTRLPAHGQMVLGEPRPEEPRGDQ 202
V + S+AID+ +L F ASL+ + T R RL P P E D
Sbjct: 177 VVEKLRSWSRAIDRRVLDF-----ASLKSGATA-TRRCRLT---------PLPHE---DG 218
Query: 203 PHSFFPESQLRAKLKCPGGSCTPGLKKIGSLKVSCEEFLLMGLRYQHLDPPSPNIDYISI 262
P + P G V CE FL G+RYQH SPN DY+ +
Sbjct: 219 PLPKYGRLVDAVGAPLPRGK-----------GVDCEAFLRAGVRYQHTATSSPNRDYVPM 267
Query: 263 QLDLT-----DTRSKIVYKSESAWLPVYIRAGIPNQIPKAAFMAVFILEVDQFILTSLTT 317
++L D S V E L V IR G N P+ +FMA ++EVD +LT+LT
Sbjct: 268 MVELLGPEGQDAGSAGVLVREHFQLLVRIRGGAENTPPRPSFMATMMMEVDPLVLTALTP 327
Query: 318 SVLDCEEDETPKPLLVFNITKAPL--------QGYVTHLLDHTR-PISSFTWKDLSDMQI 368
L E+ E+ LVFNI AP QGYV D P+S FT ++L +++I
Sbjct: 328 DALAAEDVESDPGDLVFNILNAPTHPPGHPGQQGYVVSTDDPLGLPVSFFTQQELRELKI 387
Query: 369 AYQPP-NSSHSERRHDEVELEVYDFFFERSAPMTVHISIRTADTNAPRVSWNTGLSLLEG 427
AYQPP +SH ER ++ELEV D S P +++++ +T P S N GL L EG
Sbjct: 388 AYQPPAENSHGERLF-QLELEVVDGDGAASDPFAFMVTVKSMNTLVPVASHNRGLVLFEG 446
Query: 428 QSRAIT-WEQFQVVDNDDIGAVRLVTVGGLQHGWLTLRGGKGFL--FTVADLQAGVVRYH 484
QSR ++ + D D++ V++ V GL+HG L + G FT ADL AG V Y
Sbjct: 447 QSRPLSSTHSIPISDKDNLEEVKMAAVRGLRHGQLVVFGAPAGCKYFTPADLAAGRVVYQ 506
Query: 485 HDDSDSTKDFVVFRIFDGHHSIRHKFPINVLPKDDSPPFLITNVVIELEEGQTILIQGSM 544
HD S++ D ++FR+ DGHH + FP+ +LP DD PP + TN + L EGQ + I +
Sbjct: 507 HDGSNTYSDNIIFRMEDGHHQVDFLFPLTILPVDDEPPMVNTNTGLSLTEGQVVQISPFV 566
Query: 545 LRASDVDASDDYIFFNITKPPQAGEIMKK-----PGP----------------------- 576
L A+D+D+ D I F + P G + PG
Sbjct: 567 LSATDIDSEDSTIHFVLENQPLKGNEEEPQWELAPGSSHSGHYLGDLLLQQAELPLSTED 626
Query: 577 ---------GLIGYPVHGFLQRDLFNGIIYYRHFGGEIFED---SFQFVLWDSHEPPNLS 624
GL V +LQRD+ G ++YRH G + F + D H+PPNLS
Sbjct: 627 EDWHYMEKEGLYEKVVTEWLQRDIMEGRLFYRHLGPHSPQSVMVQLAFHVQDDHDPPNLS 686
Query: 625 VPQVATIHITPVDDQLPKEAPGVSRHLVVKETEVAYITKKQLHFIDSESYDRELVYTITT 684
+ TI + PVD P+ PG + + V+E ++ + K L +ID +S D+ L YT+ T
Sbjct: 687 KQHIFTIKVQPVDILSPQLYPGTTLEMTVQEYQLTHFQKNFLRYIDQDSDDQNLWYTLLT 746
Query: 685 PPFFSFSHRHLDAGKLFMVDSIPKVVKNPTALELRSFTQHAVNYMKVAYMPPMQDIGPHC 744
P + + + AG++ + DS ++ + FTQ VN KVAY PP Q +G
Sbjct: 747 LPTDTDGNHQVRAGEIVLTDSPDTLIMH--------FTQAQVNQHKVAYQPP-QKLGIAP 797
Query: 745 RDVQFTFSVSNQHGGTLHGICFNITILPVDNQVPEAFTNPLKVTEGGQSIISTEHILISD 804
R VQFT+ V + G ++ G F + + PVDNQ PE + EGG +S+ + ++D
Sbjct: 798 RVVQFTYQVEDAAGNSVPGT-FTLFLQPVDNQPPEVTNRGFAILEGGSFNLSSNELHVTD 856
Query: 805 ADTKLDNIDLSLRELPLHGRVELNGFPLNSGGTFSWGDLHTLKVRYQHDGTEVLQDDLL- 863
DT +D I L P HG ++ + G +F D+ V YQH + D
Sbjct: 857 PDTDIDQIVFILVRGPQHGHLQYFKRCMVPGESFMQADVINGSVSYQHGRDQTTTSDTFH 916
Query: 864 LEVTDGTNSAEFVLHVEVFP--VNDEPPVL--KADLMPV-MNCSEGGEVVITSEYIFATD 918
LEV+DG + + + V P N P + + L+ V ++ E IT I
Sbjct: 917 LEVSDGVHHIPITIPISVHPNVANRSPRISLRSSSLLDVSIDVLENKATEITMGVIHGKR 976
Query: 919 VDSDNLKLMFVIAREPQHGVVRRAGVTVDQFSQRDVISEAVTYKHTGGEIGLMPCFDTIT 978
D +L L F++ P+ G + G+ ++F+Q D+I+ V Y HT GE+G D +
Sbjct: 977 KDVGDLMLSFIVKDSPKLGTILVNGLPTERFTQEDLINGRVAYAHTAGEVGFQKQHDAFS 1036
Query: 979 LVVSDGEAGPFVNGCCYNGPNPSVPLHASFPVYDLNITVYPVDNQPPSIAIGPVFVVDEG 1038
L++S ++ +V G ++ + +TV PVDN P + +G F+V EG
Sbjct: 1037 LILSK-DSYQWVVG------------NSIIEKVQVQVTVLPVDNVGPKVLVGESFIVYEG 1083
Query: 1039 CSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSVGFEKSNIGISIDSFQWKD 1098
+LT+ HL D DT D+L + S P GYLE I + G + S G I +F +D
Sbjct: 1084 EKNSLTLQHLHVEDVDTHQDELLCTVTSQPASGYLEKIASAPGSKMSQSGSPISAFSLRD 1143
Query: 1099 MNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSIIINPTNDEAPDFVVQNITV 1158
+ HINYVQS H +EP DQFT Y +DG + S + F III PTNDE P V
Sbjct: 1144 IQVRHINYVQSIHKGVEPQEDQFTFYCSDGINFSPNVFFPIIILPTNDEQPKLFAHEFKV 1203
Query: 1159 CEGQMKELDSSIISAVDLDIPQDALLFSITQKPRHGLLIDRGFSKDFSENKQPANPHQKH 1218
EG +D+ +++ D D+P + L F +T PRHG +I +Q A Q
Sbjct: 1204 LEGMSLVIDTQLLNGADADLPPNELHFQLTALPRHGRII-----------QQLATGSQ-- 1250
Query: 1219 APVHSFSMELLKTGMRLTYMHDDSESLADDFTIQLSDGKHKILKTISVEVIPVNDEKPML 1278
P+HSF+++ ++ + Y HDDSE+ D F + LSDGKH + + + V V+DE P L
Sbjct: 1251 -PIHSFTLKEIQEASTIVYEHDDSETKEDSFEVWLSDGKHTTHRKVPIVVTLVDDETPHL 1309
Query: 1279 SKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQNGQLQ-LKIGRDWV--PL 1335
+ + + G + II++ IL A D DS + + +V PQ G LQ L+ R V L
Sbjct: 1310 TVNNGLKVEKGHSEIITNRILKATDLDSDDKSLSFVLHSGPQQGLLQRLRKPRGEVRNNL 1369
Query: 1336 SPGMKCTQEEVDLNLLRYTHTGAMDSQNQDSFTFYLWDGNNRSPALDCQITIKDMEKGDI 1395
+ GM TQ+E++ L+ Y HTG D F + DG N +TI +++
Sbjct: 1370 TLGMNFTQDEINRGLICYIHTG--QEGIVDIIKFDVTDGVNTLTDHYFYVTIGNLDSVFP 1427
Query: 1396 VILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYGQIEYVHYPGVPITNF 1455
+++K + + +G R L T LL + +E + IT P G +E Y G PI +F
Sbjct: 1428 EVISKRITLIEGARVTL-TNNLLTNSDINSSDEHHFSITRAPSLGHLESSDYAGEPIASF 1486
Query: 1456 SQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGL 1515
+Q+ + + YVH S D F F + L F I + VD P++T ++ L
Sbjct: 1487 TQLQLASNKISYVHTSNDEKKMDSFEFQVIGELYPVFRTFRIFITDVDNKKPILTIHR-L 1545
Query: 1516 RLAQGAVGLLSPDLLQLTDPDTPAENLTFLLVQLPQHGQLYLWGTGLLQHNFTQQDVDSK 1575
L + L++ L + D DTP + + F + Q+P HG++ G+ + FT+QD++
Sbjct: 1546 TLQKEDSQLITLLELTVEDSDTPDDLILFTITQVPMHGKILYNGSRPVT-TFTKQDLNKN 1604
Query: 1576 NVAYRHSGGDSQTDCFTFMATDGTNQGFIV---NGRVWEEPVLFTIQVDQLDKTAPRITL 1632
++Y+H G ++ D F+ TDGT+ F V +P + +Q+ LD P+IT
Sbjct: 1605 LISYKHDGSETTEDSFSLTVTDGTHTDFYVLPDTALATHKPQVMRVQIRSLDNRLPQITT 1664
Query: 1633 LHSPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHE 1692
+ L G G ITS+ LKA D D+ + +K+ +GP+HG + T G
Sbjct: 1665 NRGAPALKRLHTGHMGFLITSKSLKAEDQDSPHRLLKYKVTRGPEHGFIIKTGLGNQSTR 1724
Query: 1693 KFSQKDLNSKTILYIINPSLEVNSDTVEFQIMDPTGNSATPQILELKWSHIEWSQTEYEV 1752
F+Q D++ I Y++N + D F + D GN T Q L W+ I + Y V
Sbjct: 1725 VFTQADIDEMKISYVLNEGSNASKDIFYFSVEDNGGNKLTNQPFHLNWAWICLEKEYYIV 1784
Query: 1753 CENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQFDPGMSTKMWNIA 1812
E+ L + + RRGY +++F+ I +A KDF +K IQF+PG +T W +
Sbjct: 1785 DEDSTFLEVTLTRRGYLGETSFISIGTKDETAKKDKDFKWKTNKQIQFNPGQTTATWRVR 1844
Query: 1813 ITYDGLEEDDEVFEVILNSPVNAVLGTKTKAAVKILD 1849
I D E E F++IL+ P+ AVL A V+I+D
Sbjct: 1845 IIPDNEYETSETFQIILSEPLMAVLEFPEMATVEIVD 1881
Score = 215 bits (548), Expect = 3e-55
Identities = 352/1512 (23%), Positives = 596/1512 (39%), Gaps = 237/1512 (15%)
Query: 475 DLQAGVVRYHHDDSDSTKDFVV---FRIFDGHH----SIRHKFPINVLPKDDSPPFLITN 527
D+ G + Y H S + +V F + D H S +H F I V P D P L
Sbjct: 649 DIMEGRLFYRHLGPHSPQSVMVQLAFHVQDDHDPPNLSKQHIFTIKVQPVDILSPQLYPG 708
Query: 528 VVIEL--EEGQTILIQGSMLRASDVDASDDYIFFNITKPP---------QAGEIMKKPGP 576
+E+ +E Q Q + LR D D+ D +++ + P +AGEI+ P
Sbjct: 709 TTLEMTVQEYQLTHFQKNFLRYIDQDSDDQNLWYTLLTLPTDTDGNHQVRAGEIVLTDSP 768
Query: 577 GLIGYPVHGFLQRDLFNGIIYYRH-----FGGEIFEDSFQFVLWDSHEPPNLSVPQVATI 631
+ + F Q + + Y+ + + ++Q + SVP T+
Sbjct: 769 DTL---IMHFTQAQVNQHKVAYQPPQKLGIAPRVVQFTYQV-----EDAAGNSVPGTFTL 820
Query: 632 HITPVDDQLPKEAPGVSRHLVVKETEVAYITKKQLHFIDSESYDRELVYTITTPPFFSFS 691
+ PVD+Q P+ +R + E ++ +LH D ++ ++V+ + P
Sbjct: 821 FLQPVDNQPPEVT---NRGFAILEGGSFNLSSNELHVTDPDTDIDQIVFILVRGP----Q 873
Query: 692 HRHLDAGKLFMVDSIPKVVKNPTALELRSFTQHAVNYMKVAYMPPMQDIGPHCRD---VQ 748
H HL K MV SF Q V V+Y H RD
Sbjct: 874 HGHLQYFKRCMVPG-------------ESFMQADVINGSVSYQ--------HGRDQTTTS 912
Query: 749 FTFSVSNQHGGTLHGICFNITILP-VDNQVPEAFTNPLKVTEGGQSII---STEHILISD 804
TF + G I I++ P V N+ P + + ++ +TE +
Sbjct: 913 DTFHLEVSDGVHHIPITIPISVHPNVANRSPRISLRSSSLLDVSIDVLENKATEITMGVI 972
Query: 805 ADTKLDNIDLSL----RELPLHGRVELNGFPLNSGGTFSWGDLHTLKVRYQHDGTEV--- 857
+ D DL L ++ P G + +NG P F+ DL +V Y H EV
Sbjct: 973 HGKRKDVGDLMLSFIVKDSPKLGTILVNGLPTER---FTQEDLINGRVAYAHTAGEVGFQ 1029
Query: 858 ---------LQDDLLLEVTDGTNSAEFVLHVEVFPV-NDEPPVLKADLMPVMNCSEGGEV 907
L D V + + + V V PV N P VL + V EG +
Sbjct: 1030 KQHDAFSLILSKDSYQWVVGNSIIEKVQVQVTVLPVDNVGPKVLVGESFIVY---EGEKN 1086
Query: 908 VITSEYIFATDVDSDNLKLMFVIAREPQHGVVRR-----------AGVTVDQFSQRDVIS 956
+T +++ DVD+ +L+ + +P G + + +G + FS RD+
Sbjct: 1087 SLTLQHLHVEDVDTHQDELLCTVTSQPASGYLEKIASAPGSKMSQSGSPISAFSLRDIQV 1146
Query: 957 EAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVNGCCYNGPNPSVPLHASFPVYDLNIT 1016
+ Y + + G+ P D T SDG +N PN P I
Sbjct: 1147 RHINYVQSIHK-GVEPQEDQFTFYCSDG-----INF----SPNVFFP-----------II 1185
Query: 1017 VYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENI 1076
+ P +++ P + F V EG S + L+ D D ++L F L + P+ G +
Sbjct: 1186 ILPTNDEQPKL-FAHEFKVLEGMSLVIDTQLLNGADADLPPNELHFQLTALPRHGRIIQQ 1244
Query: 1077 LPSVGFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHS-LEI 1135
L + G + I SF K++ + + H E D F V+++DGKH + ++
Sbjct: 1245 L-ATGSQP------IHSFTLKEIQ--EASTIVYEHDDSETKEDSFEVWLSDGKHTTHRKV 1295
Query: 1136 PFSIIINPTNDEAPDFVVQN-ITVCEGQMKELDSSIISAVDLDIPQDALLFSITQKPRHG 1194
P I++ +DE P V N + V +G + + + I+ A DLD +L F + P+ G
Sbjct: 1296 P--IVVTLVDDETPHLTVNNGLKVEKGHSEIITNRILKATDLDSDDKSLSFVLHSGPQQG 1353
Query: 1195 LLIDRGFSKDFSENKQPANPHQKHAPVH-SFSMELLKTGMRLTYMHDDSESLADDFTIQL 1253
LL ++P + + + +F+ + + G+ + Y+H E + D +
Sbjct: 1354 LL---------QRLRKPRGEVRNNLTLGMNFTQDEINRGL-ICYIHTGQEGIVDIIKFDV 1403
Query: 1254 SDGKHKILKTISVEVIPVNDE--KPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKI 1311
+DG + + I D ++SK+ I + G +++ +L+ D +S E
Sbjct: 1404 TDGVNTLTDHYFYVTIGNLDSVFPEVISKR--ITLIEGARVTLTNNLLTNSDINSSDEH- 1460
Query: 1312 YYVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNLLRYTHTGAMDSQNQDSFTFYL 1371
++ R P G L+ D+ P TQ ++ N + Y HT + D + DSF F +
Sbjct: 1461 HFSITRAPSLGHLE---SSDYAG-EPIASFTQLQLASNKISYVHT-SNDEKKMDSFEFQV 1515
Query: 1372 WDGNNRSPALDCQITIKDMEKGDIVILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEEL-L 1430
G +I I D++ ++ L + K D +T L V+ +D P++L L
Sbjct: 1516 I-GELYPVFRTFRIFITDVDNKKPILTIHRLTLQKEDSQLITLLEL-TVEDSDTPDDLIL 1573
Query: 1431 YVITSPPRYGQIEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRT 1490
+ IT P +G+I Y P+T F++ D+ + Y H T + D F +++G T
Sbjct: 1574 FTITQVPMHGKILY--NGSRPVTTFTKQDLNKNLISYKHDGSET-TEDSFSLTVTDGTHT 1630
Query: 1491 EH-------------GVFEITLETVDRALPVVTRNKGL----RLAQGAVG-LLSPDLLQL 1532
+ V + + ++D LP +T N+G RL G +G L++ L+
Sbjct: 1631 DFYVLPDTALATHKPQVMRVQIRSLDNRLPQITTNRGAPALKRLHTGHMGFLITSKSLKA 1690
Query: 1533 TDPDTPAENLTFLLVQLPQHGQLYLWGTGLLQHN-FTQQDVDSKNVAY-RHSGGDSQTDC 1590
D D+P L + + + P+HG + G G FTQ D+D ++Y + G ++ D
Sbjct: 1691 EDQDSPHRLLKYKVTRGPEHGFIIKTGLGNQSTRVFTQADIDEMKISYVLNEGSNASKDI 1750
Query: 1591 FTFMATDG-----TNQGFIVNGR-VWEEPVLFTIQVDQLDKTAPRITLLHSPSQVGLLKN 1644
F F D TNQ F +N + E + + D T L +V L +
Sbjct: 1751 FYFSVEDNGGNKLTNQPFHLNWAWICLEKEYYIVDEDS--------TFL----EVTLTRR 1798
Query: 1645 GCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHEKFSQKDLNSKTI 1704
G G TS + + +T FK + TT + + +
Sbjct: 1799 GYLGE--TSFISIGTKDETAKKDKDFKWKTNKQIQFNPGQTTATWRVRIIPDNEYETSET 1856
Query: 1705 LYII--NPSLEVNS--DTVEFQIMDPTGNSATPQILELKWSHIEWSQTEYEVCENVGLLP 1760
II P + V + +I+DP G+ +T I E EY++ E++G L
Sbjct: 1857 FQIILSEPLMAVLEFPEMATVEIVDP-GDESTVYIPE----------AEYKIEEDIGELL 1905
Query: 1761 LEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPS----------KLIQFDPGMSTKMWN 1810
+ + R G + V Q SA TV+ S ++ FD + K
Sbjct: 1906 IPVRRSGDASQELIVICSTRQGSATGTISSTVLFSDYISRPEDHTSILHFDKNETQKTCQ 1965
Query: 1811 IAITYDGLEEDDEVFEVILNSPVNAVLGTK---TKAAV-------KILDSKGGQCHPSYS 1860
+ I D L E++E F V L PV LG + TK + +L + H + S
Sbjct: 1966 VLIIDDSLYEEEESFSVSLRLPVGGQLGARFPTTKVTILADRYDEPVLHFGDAEYHVNES 2025
Query: 1861 SNQSKHSTWEKG 1872
+ + W +G
Sbjct: 2026 ARYVEVCVWRRG 2037
Score = 208 bits (529), Expect = 5e-53
Identities = 315/1437 (21%), Positives = 567/1437 (39%), Gaps = 212/1437 (14%)
Query: 504 HSIRHKFPINVLPKDDSPPFLITNVVIELEEGQTILIQGSMLRASDVDASDDYIFFNITK 563
+S+ F + + P D+ PP +TN + EG + + + L +D D D I F + +
Sbjct: 812 NSVPGTFTLFLQPVDNQPPE-VTNRGFAILEGGSFNLSSNELHVTDPDTDIDQIVFILVR 870
Query: 564 PPQAGEIMKKPGPGLIGYPVHGFLQRDLFNGIIYYRHFGGEIF-EDSFQFVLWDSHEPPN 622
PQ G + + P F+Q D+ NG + Y+H + D+F + D
Sbjct: 871 GPQHGHLQYFKRCMV---PGESFMQADVINGSVSYQHGRDQTTTSDTFHLEVSDGVHHIP 927
Query: 623 LSVPQVATIHITP-VDDQLPKEAPGVSRHLVVK----ETEVAYITKKQLHFIDSESYDRE 677
+++P I + P V ++ P+ + S L V E + IT +H + D
Sbjct: 928 ITIP----ISVHPNVANRSPRISLRSSSLLDVSIDVLENKATEITMGVIHGKRKDVGDLM 983
Query: 678 LVYTITTPPFFSFSHRHLDAGKLFMVDSIPKVVKNPTALELRSFTQHAVNYMKVAYMPPM 737
L + + P +V+ +P FTQ + +VAY
Sbjct: 984 LSFIVKDSPKLG----------TILVNGLPT----------ERFTQEDLINGRVAYAHTA 1023
Query: 738 QDIGPHCRDVQFTFSVSNQH------GGTLHGICFNITILPVDNQVPEAFTNP-LKVTEG 790
++G + F+ +S + + +T+LPVDN P+ V EG
Sbjct: 1024 GEVGFQKQHDAFSLILSKDSYQWVVGNSIIEKVQVQVTVLPVDNVGPKVLVGESFIVYEG 1083
Query: 791 GQSIISTEHILISDADTKLDNIDLSLRELPLHGRVE----LNGFPLNSGGT----FSWGD 842
++ ++ +H+ + D DT D + ++ P G +E G ++ G+ FS D
Sbjct: 1084 EKNSLTLQHLHVEDVDTHQDELLCTVTSQPASGYLEKIASAPGSKMSQSGSPISAFSLRD 1143
Query: 843 LHTLKVRYQ---HDGTEVLQDDLLLEVTDGTN-SAEFVLHVEVFPVNDEPPVLKADLMPV 898
+ + Y H G E +D +DG N S + + P NDE P L A V
Sbjct: 1144 IQVRHINYVQSIHKGVEPQEDQFTFYCSDGINFSPNVFFPIIILPTNDEQPKLFAHEFKV 1203
Query: 899 MNCSEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHGVVRRAGVTVDQ----FSQRDV 954
+ EG +VI ++ + D D +L F + P+HG + + T Q F+ +++
Sbjct: 1204 L---EGMSLVIDTQLLNGADADLPPNELHFQLTALPRHGRIIQQLATGSQPIHSFTLKEI 1260
Query: 955 I-SEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVNGCCYNGPNPSVPLHASFPVYDL 1013
+ + Y+H E D+ + +SDG+ H P
Sbjct: 1261 QEASTIVYEHDDSETKE----DSFEVWLSDGKH----------------TTHRKVP---- 1296
Query: 1014 NITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYL 1073
I V VD++ P + + V++G S +T L ATD D+ L FVL S PQ G L
Sbjct: 1297 -IVVTLVDDETPHLTVNNGLKVEKGHSEIITNRILKATDLDSDDKSLSFVLHSGPQQGLL 1355
Query: 1074 ENILPSVGFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSL 1133
+ + G ++N+ + ++ F ++N I Y+ H E D VTDG +
Sbjct: 1356 QRLRKPRGEVRNNLTLGMN-FTQDEINRGLICYI---HTGQEGIVDIIKFDVTDGVNTLT 1411
Query: 1134 EIPFSIIINPTNDEAPDFVVQNITVCEGQMKELDSSIISAVDLDIPQDALLFSITQKPRH 1193
+ F + I + P+ + + IT+ EG L +++++ D++ D FSIT+ P
Sbjct: 1412 DHYFYVTIGNLDSVFPEVISKRITLIEGARVTLTNNLLTNSDIN-SSDEHHFSITRAPSL 1470
Query: 1194 GLLIDRGFSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMH-DDSESLADDFTIQ 1252
G L ++ + P+ SF+ +L +++Y+H + E D F Q
Sbjct: 1471 GHLESSDYAGE---------------PIASFT-QLQLASNKISYVHTSNDEKKMDSFEFQ 1514
Query: 1253 LSDGKHKILKTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIY 1312
+ + + +T + + V+++KP+L+ + + ++++I+ L+ D D+P + I
Sbjct: 1515 VIGELYPVFRTFRIFITDVDNKKPILTIH-RLTLQKEDSQLITLLELTVEDSDTPDDLIL 1573
Query: 1313 YVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNLLRYTHTGAMDSQNQDSFTFYLW 1372
+ ++P +G++ R P T+++++ NL+ Y H G+ +DSF+ +
Sbjct: 1574 FTITQVPMHGKILYNGSR------PVTTFTKQDLNKNLISYKHDGS--ETTEDSFSLTVT 1625
Query: 1373 DGNN--------------RSPALDCQITIKDMEKGDIVILTKPLVVSK---GDRGFLTTT 1415
DG + + + QI D I + + G GFL T+
Sbjct: 1626 DGTHTDFYVLPDTALATHKPQVMRVQIRSLDNRLPQITTNRGAPALKRLHTGHMGFLITS 1685
Query: 1416 TLLAVDGTDKPEELL-YVITSPPRYGQIEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVT 1474
L + D P LL Y +T P +G I F+Q D+ + Y
Sbjct: 1686 KSLKAEDQDSPHRLLKYKVTRGPEHGFIIKTGLGNQSTRVFTQADIDEMKISY------- 1738
Query: 1475 VSSDRFRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGLRLAQGAVGLLSPDLLQLTD 1534
+++ G +F ++E N G +L L + +
Sbjct: 1739 --------VLNEGSNASKDIFYFSVED----------NGGNKLTNQPFHLNWAWICLEKE 1780
Query: 1535 PDTPAENLTFLLVQLPQHGQLYLWGTGLLQHNFTQQDVDSKNVAYRHSGGDSQTDCFTFM 1594
E+ TFL V L + G YL T + T+ + K+ ++ ++ F
Sbjct: 1781 YYIVDEDSTFLEVTLTRRG--YLGETSFISIG-TKDETAKKDKDFKWK--TNKQIQFNPG 1835
Query: 1595 ATDGTNQGFIVNGRVWEEPVLFTIQVDQLDKTAPRITLLHSPSQ--VGLLKNGCYG-IYI 1651
T T + I+ +E F I + + P + +L P V ++ G +YI
Sbjct: 1836 QTTATWRVRIIPDNEYETSETFQIILSE-----PLMAVLEFPEMATVEIVDPGDESTVYI 1890
Query: 1652 TSRVLKASDP------------DTEDDQIIF-KILQGPKHGHLENTTT-GEFIHEK---- 1693
K + D + I+ QG G + +T ++I
Sbjct: 1891 PEAEYKIEEDIGELLIPVRRSGDASQELIVICSTRQGSATGTISSTVLFSDYISRPEDHT 1950
Query: 1694 ----FSQKDLNSKTILYIINPSLEVNSDTVEFQIMDPTGNSATPQ-------ILELKWSH 1742
F + + + II+ SL ++ + P G + IL ++
Sbjct: 1951 SILHFDKNETQKTCQVLIIDDSLYEEEESFSVSLRLPVGGQLGARFPTTKVTILADRYDE 2010
Query: 1743 --IEWSQTEYEVCENVGLLPLEIIRRGYSMDS----AFVGIKVNQVSAAVGKDFTVIPSK 1796
+ + EY V E+ + + + RRG + A K Q SA G D+ I S+
Sbjct: 2011 PVLHFGDAEYHVNESARYVEVCVWRRGTDLSQPSSIAVRSRKSEQESAEAGTDYVGI-SR 2069
Query: 1797 LIQFDPGMSTKMWNIAITYDGLE---EDDEVFEVILNSPVNAVLGTKTKAAVKILDS 1850
+ F PG+ + + + I D + E E FE++L P+ AVLG K + I D+
Sbjct: 2070 NLDFAPGVRMQTFQVTILDDLGQPTLEGPEKFELLLQMPMGAVLGEPNKTTIFIEDT 2126
>gi|169166334 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
sapiens]
Length = 2139
Score = 851 bits (2199), Expect = 0.0
Identities = 608/1897 (32%), Positives = 913/1897 (48%), Gaps = 145/1897 (7%)
Query: 23 PTFISINRGVRVMKGHSAFLSGDDLKFAIPKEKDACKVEVVMNEPITQRVGKLTPQVFDC 82
P+ + N G+RV G S +L D L+ + + + EV + + + + G L+P+ F C
Sbjct: 60 PSVLIANPGLRVPLGRSLWL--DPLRDLVIGVQPGDRCEVTVLDALPRLKGALSPRRFPC 117
Query: 83 HFLPNEVKYVHNGCPILDEDTVKLRLYRFTERDTFIETFILWVYLLEPDCNIIHMSNNVL 142
F P +V+Y H G V L+L T + F L V L+ ++ N L
Sbjct: 118 TFGPRQVQYTHFGSHSPGRARVLLQLRYDAPTHTLVLPFTLAVDLVFSQLELV-TRNRPL 176
Query: 143 EVPEFNGLSQAIDKNLLRFDYDRMASLECTVSLDTARTRLPAHGQMVLGEPRPEEPRGDQ 202
V + S+AID+ +L F ASL+ + T R RL P P E D
Sbjct: 177 VVEKLRSWSRAIDRRVLDF-----ASLKSGATA-TRRCRLT---------PLPHE---DG 218
Query: 203 PHSFFPESQLRAKLKCPGGSCTPGLKKIGSLKVSCEEFLLMGLRYQHLDPPSPNIDYISI 262
P + P G V CE FL G+RYQH SPN DY+ +
Sbjct: 219 PLPKYGRLVDAVGAPLPRGK-----------GVDCEAFLRAGVRYQHTATSSPNRDYVPM 267
Query: 263 QLDLT-----DTRSKIVYKSESAWLPVYIRAGIPNQIPKAAFMAVFILEVDQFILTSLTT 317
++L D S V E L V IR G N P+ +FMA ++EVD +LT+LT
Sbjct: 268 MVELLGPEGQDAGSAGVLVREHFQLLVRIRGGAENTPPRPSFMATMMMEVDPLVLTALTP 327
Query: 318 SVLDCEEDETPKPLLVFNITKAPL--------QGYVTHLLDHTR-PISSFTWKDLSDMQI 368
L E+ E+ LVFNI AP QGYV D P+S FT ++L +++I
Sbjct: 328 DALAAEDVESDPGDLVFNILNAPTHPPGHPGQQGYVVSTDDPLGLPVSFFTQQELRELKI 387
Query: 369 AYQPP-NSSHSERRHDEVELEVYDFFFERSAPMTVHISIRTADTNAPRVSWNTGLSLLEG 427
AYQPP +SH ER ++ELEV D S P +++++ +T P S N GL L EG
Sbjct: 388 AYQPPAENSHGERLF-QLELEVVDGDGAASDPFAFMVTVKSMNTLVPVASHNRGLVLFEG 446
Query: 428 QSRAIT-WEQFQVVDNDDIGAVRLVTVGGLQHGWLTLRGGKGFL--FTVADLQAGVVRYH 484
QSR ++ + D D++ V++ V GL+HG L + G FT ADL AG V Y
Sbjct: 447 QSRPLSSTHSIPISDKDNLEEVKMAAVRGLRHGQLVVFGAPAGCKYFTPADLAAGRVVYQ 506
Query: 485 HDDSDSTKDFVVFRIFDGHHSIRHKFPINVLPKDDSPPFLITNVVIELEEGQTILIQGSM 544
HD S++ D ++FR+ DGHH + FP+ +LP DD PP + TN + L EGQ + I +
Sbjct: 507 HDGSNTYSDNIIFRMEDGHHQVDFLFPLTILPVDDEPPMVNTNTGLSLTEGQVVQISPFV 566
Query: 545 LRASDVDASDDYIFFNITKPPQAGEIMKK-----PGP----------------------- 576
L A+D+D+ D I F + P G + PG
Sbjct: 567 LSATDIDSEDSTIHFVLENQPLKGNEEEPQWELAPGSSHSGHYLGDLLLQQAELPLSTED 626
Query: 577 ---------GLIGYPVHGFLQRDLFNGIIYYRHFGGEIFED---SFQFVLWDSHEPPNLS 624
GL V +LQRD+ G ++YRH G + F + D H+PPNLS
Sbjct: 627 EDWHYMEKEGLYEKVVTEWLQRDIMEGRLFYRHLGPHSPQSVMVQLAFHVQDDHDPPNLS 686
Query: 625 VPQVATIHITPVDDQLPKEAPGVSRHLVVKETEVAYITKKQLHFIDSESYDRELVYTITT 684
+ TI + PVD P+ PG + + V+E ++ + K L +ID +S D+ L YT+ T
Sbjct: 687 KQHIFTIKVQPVDILSPQLYPGTTLEMTVQEYQLTHFQKNFLRYIDQDSDDQNLWYTLLT 746
Query: 685 PPFFSFSHRHLDAGKLFMVDSIPKVVKNPTALELRSFTQHAVNYMKVAYMPPMQDIGPHC 744
P + + + AG++ + DS ++ + FTQ VN KVAY PP Q +G
Sbjct: 747 LPTDTDGNHQVRAGEIVLTDSPDTLIMH--------FTQAQVNQHKVAYQPP-QKLGIAP 797
Query: 745 RDVQFTFSVSNQHGGTLHGICFNITILPVDNQVPEAFTNPLKVTEGGQSIISTEHILISD 804
R VQFT+ V + G ++ G F + + PVDNQ PE + EGG +S+ + ++D
Sbjct: 798 RVVQFTYQVEDAAGNSVPGT-FTLFLQPVDNQPPEVTNRGFAILEGGSFNLSSNELHVTD 856
Query: 805 ADTKLDNIDLSLRELPLHGRVELNGFPLNSGGTFSWGDLHTLKVRYQHDGTEVLQDDLL- 863
DT +D I L P HG ++ + G +F D+ V YQH + D
Sbjct: 857 PDTDIDQIVFILVRGPQHGHLQYFKRCMVPGESFMQADVINGSVSYQHGRDQTTTSDTFH 916
Query: 864 LEVTDGTNSAEFVLHVEVFP--VNDEPPVL--KADLMPV-MNCSEGGEVVITSEYIFATD 918
LEV+DG + + + V P N P + + L+ V ++ E IT I
Sbjct: 917 LEVSDGVHHIPITIPISVHPNVANRSPRISLRSSSLLDVSIDVLENKATEITMGVIHGKR 976
Query: 919 VDSDNLKLMFVIAREPQHGVVRRAGVTVDQFSQRDVISEAVTYKHTGGEIGLMPCFDTIT 978
D +L L F++ P+ G + G+ ++F+Q D+I+ V Y HT GE+G D +
Sbjct: 977 KDVGDLMLSFIVKDSPKLGTILVNGLPTERFTQEDLINGRVAYAHTAGEVGFQKQHDAFS 1036
Query: 979 LVVSDGEAGPFVNGCCYNGPNPSVPLHASFPVYDLNITVYPVDNQPPSIAIGPVFVVDEG 1038
L++S ++ +V G ++ + +TV PVDN P + +G F+V EG
Sbjct: 1037 LILSK-DSYQWVVG------------NSIIEKVQVQVTVLPVDNVGPKVFVGESFIVYEG 1083
Query: 1039 CSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSVGFEKSNIGISIDSFQWKD 1098
+LT+ HL D DT D+L + S P GYLE I + G + S G I +F +D
Sbjct: 1084 EKNSLTLQHLHVEDVDTHQDELLCTVTSQPASGYLEKIASAPGSKMSQSGSPISAFSLRD 1143
Query: 1099 MNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSIIINPTNDEAPDFVVQNITV 1158
+ HINYVQS H +EP DQFT Y +DG + S + F III PTNDE P V
Sbjct: 1144 IQVRHINYVQSIHKGVEPQEDQFTFYCSDGINFSPNVFFPIIILPTNDEQPKLFAHEFKV 1203
Query: 1159 CEGQMKELDSSIISAVDLDIPQDALLFSITQKPRHGLLIDRGFSKDFSENKQPANPHQKH 1218
EG +D+ +++ D D+P + L F +T PRHG +I +Q A Q
Sbjct: 1204 LEGMSLVIDTQLLNGADADLPPNELHFQLTALPRHGRII-----------QQLATGSQ-- 1250
Query: 1219 APVHSFSMELLKTGMRLTYMHDDSESLADDFTIQLSDGKHKILKTISVEVIPVNDEKPML 1278
P+HSF+++ ++ + Y HDDSE+ D F + LSDGKH + + + V V+DE P L
Sbjct: 1251 -PIHSFTLKEIQEASTIVYEHDDSETKEDSFEVWLSDGKHTTHRKVPIVVTLVDDETPHL 1309
Query: 1279 SKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFERLPQNGQLQ-LKIGRDWV--PL 1335
+ + + G + II++ IL A D DS + + +V PQ G LQ L+ R V L
Sbjct: 1310 TVNNGLKVEKGHSEIITNRILKATDLDSDDKSLSFVLHSGPQQGLLQRLRKPRGEVRNNL 1369
Query: 1336 SPGMKCTQEEVDLNLLRYTHTGAMDSQNQDSFTFYLWDGNNRSPALDCQITIKDMEKGDI 1395
+ GM TQ+E++ L+ Y HTG D F + DG N +TI +++
Sbjct: 1370 TLGMNFTQDEINRGLICYIHTG--QEGIVDIIKFDVTDGVNTLTDHYFYVTIGNLDSVFP 1427
Query: 1396 VILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYGQIEYVHYPGVPITNF 1455
+++K + + +G R L T LL + +E + IT P G +E Y G PI +F
Sbjct: 1428 EVISKRITLIEGARVTL-TNNLLTNSDINSSDEHHFSITRAPSLGHLESSDYAGEPIASF 1486
Query: 1456 SQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGL 1515
+Q+ + + YVH S D F F + L F I + VD P++T ++ L
Sbjct: 1487 TQLQLASNKISYVHTSNDEKKMDSFEFQVIGELYPVFRTFRIFITDVDNKKPILTIHR-L 1545
Query: 1516 RLAQGAVGLLSPDLLQLTDPDTPAENLTFLLVQLPQHGQLYLWGTGLLQHNFTQQDVDSK 1575
L + L++ L + D DTP + + F + Q+P HG++ G+ + FT+QD++
Sbjct: 1546 TLQKEDSQLITLLELTVEDSDTPDDLILFTITQVPMHGKILYNGSRPVT-TFTKQDLNKN 1604
Query: 1576 NVAYRHSGGDSQTDCFTFMATDGTNQGFIV---NGRVWEEPVLFTIQVDQLDKTAPRITL 1632
++Y+H G ++ D F+ TDGT+ F V +P + +Q+ LD P+IT
Sbjct: 1605 LISYKHDGSETTEDSFSLTVTDGTHTDFYVLPDTALATHKPQVMRVQIRSLDNRLPQITT 1664
Query: 1633 LHSPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHE 1692
+ L G G ITS+ LKA D D+ + +K+ +GP+HG + T G
Sbjct: 1665 NRGAPALKRLHTGHMGFLITSKSLKAEDQDSPHRLLKYKVTRGPEHGFIIKTGLGNQSTR 1724
Query: 1693 KFSQKDLNSKTILYIINPSLEVNSDTVEFQIMDPTGNSATPQILELKWSHIEWSQTEYEV 1752
F+Q D++ I Y++N + D F + D GN T Q L W+ I + Y V
Sbjct: 1725 VFTQADIDEMKISYVLNEGSNASKDIFYFSVEDNGGNKLTNQPFHLNWAWICLEKEYYIV 1784
Query: 1753 CENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQFDPGMSTKMWNIA 1812
E+ L + + RRGY +++F+ I +A KDF +K IQF+PG +T W +
Sbjct: 1785 DEDSTFLEVTLTRRGYLGETSFISIGTKDETAKKDKDFKWKTNKQIQFNPGQTTATWRVR 1844
Query: 1813 ITYDGLEEDDEVFEVILNSPVNAVLGTKTKAAVKILD 1849
I D E E F++IL+ P+ AVL A V+I+D
Sbjct: 1845 IIPDNEYETSETFQIILSEPLMAVLEFPEMATVEIVD 1881
Score = 214 bits (544), Expect = 1e-54
Identities = 349/1511 (23%), Positives = 595/1511 (39%), Gaps = 235/1511 (15%)
Query: 475 DLQAGVVRYHHDDSDSTKDFVV---FRIFDGHH----SIRHKFPINVLPKDDSPPFLITN 527
D+ G + Y H S + +V F + D H S +H F I V P D P L
Sbjct: 649 DIMEGRLFYRHLGPHSPQSVMVQLAFHVQDDHDPPNLSKQHIFTIKVQPVDILSPQLYPG 708
Query: 528 VVIEL--EEGQTILIQGSMLRASDVDASDDYIFFNITKPP---------QAGEIMKKPGP 576
+E+ +E Q Q + LR D D+ D +++ + P +AGEI+ P
Sbjct: 709 TTLEMTVQEYQLTHFQKNFLRYIDQDSDDQNLWYTLLTLPTDTDGNHQVRAGEIVLTDSP 768
Query: 577 GLIGYPVHGFLQRDLFNGIIYYRH-----FGGEIFEDSFQFVLWDSHEPPNLSVPQVATI 631
+ + F Q + + Y+ + + ++Q + SVP T+
Sbjct: 769 DTL---IMHFTQAQVNQHKVAYQPPQKLGIAPRVVQFTYQV-----EDAAGNSVPGTFTL 820
Query: 632 HITPVDDQLPKEAPGVSRHLVVKETEVAYITKKQLHFIDSESYDRELVYTITTPPFFSFS 691
+ PVD+Q P+ +R + E ++ +LH D ++ ++V+ + P
Sbjct: 821 FLQPVDNQPPEVT---NRGFAILEGGSFNLSSNELHVTDPDTDIDQIVFILVRGP----Q 873
Query: 692 HRHLDAGKLFMVDSIPKVVKNPTALELRSFTQHAVNYMKVAYMPPMQDIGPHCRD---VQ 748
H HL K MV SF Q V V+Y H RD
Sbjct: 874 HGHLQYFKRCMVPG-------------ESFMQADVINGSVSYQ--------HGRDQTTTS 912
Query: 749 FTFSVSNQHGGTLHGICFNITILP-VDNQVPEAFTNPLKVTEGGQSII---STEHILISD 804
TF + G I I++ P V N+ P + + ++ +TE +
Sbjct: 913 DTFHLEVSDGVHHIPITIPISVHPNVANRSPRISLRSSSLLDVSIDVLENKATEITMGVI 972
Query: 805 ADTKLDNIDLSL----RELPLHGRVELNGFPLNSGGTFSWGDLHTLKVRYQHDGTEV--- 857
+ D DL L ++ P G + +NG P F+ DL +V Y H EV
Sbjct: 973 HGKRKDVGDLMLSFIVKDSPKLGTILVNGLPTER---FTQEDLINGRVAYAHTAGEVGFQ 1029
Query: 858 ---------LQDDLLLEVTDGTNSAEFVLHVEVFPVNDEPPVLKADLMPVMNCSEGGEVV 908
L D V + + + V V PV++ P K + EG +
Sbjct: 1030 KQHDAFSLILSKDSYQWVVGNSIIEKVQVQVTVLPVDNVGP--KVFVGESFIVYEGEKNS 1087
Query: 909 ITSEYIFATDVDSDNLKLMFVIAREPQHGVVRR-----------AGVTVDQFSQRDVISE 957
+T +++ DVD+ +L+ + +P G + + +G + FS RD+
Sbjct: 1088 LTLQHLHVEDVDTHQDELLCTVTSQPASGYLEKIASAPGSKMSQSGSPISAFSLRDIQVR 1147
Query: 958 AVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVNGCCYNGPNPSVPLHASFPVYDLNITV 1017
+ Y + + G+ P D T SDG +N PN P I +
Sbjct: 1148 HINYVQSIHK-GVEPQEDQFTFYCSDG-----INF----SPNVFFP-----------III 1186
Query: 1018 YPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENIL 1077
P +++ P + F V EG S + L+ D D ++L F L + P+ G + L
Sbjct: 1187 LPTNDEQPKL-FAHEFKVLEGMSLVIDTQLLNGADADLPPNELHFQLTALPRHGRIIQQL 1245
Query: 1078 PSVGFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHS-LEIP 1136
+ G + I SF K++ + + H E D F V+++DGKH + ++P
Sbjct: 1246 -ATGSQP------IHSFTLKEIQ--EASTIVYEHDDSETKEDSFEVWLSDGKHTTHRKVP 1296
Query: 1137 FSIIINPTNDEAPDFVVQN-ITVCEGQMKELDSSIISAVDLDIPQDALLFSITQKPRHGL 1195
I++ +DE P V N + V +G + + + I+ A DLD +L F + P+ GL
Sbjct: 1297 --IVVTLVDDETPHLTVNNGLKVEKGHSEIITNRILKATDLDSDDKSLSFVLHSGPQQGL 1354
Query: 1196 LIDRGFSKDFSENKQPANPHQKHAPVH-SFSMELLKTGMRLTYMHDDSESLADDFTIQLS 1254
L ++P + + + +F+ + + G+ + Y+H E + D ++
Sbjct: 1355 L---------QRLRKPRGEVRNNLTLGMNFTQDEINRGL-ICYIHTGQEGIVDIIKFDVT 1404
Query: 1255 DGKHKILKTISVEVIPVNDE--KPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIY 1312
DG + + I D ++SK+ I + G +++ +L+ D +S E +
Sbjct: 1405 DGVNTLTDHYFYVTIGNLDSVFPEVISKR--ITLIEGARVTLTNNLLTNSDINSSDEH-H 1461
Query: 1313 YVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNLLRYTHTGAMDSQNQDSFTFYLW 1372
+ R P G L+ D+ P TQ ++ N + Y HT + D + DSF F +
Sbjct: 1462 FSITRAPSLGHLE---SSDYAG-EPIASFTQLQLASNKISYVHT-SNDEKKMDSFEFQVI 1516
Query: 1373 DGNNRSPALDCQITIKDMEKGDIVILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEEL-LY 1431
G +I I D++ ++ L + K D +T L V+ +D P++L L+
Sbjct: 1517 -GELYPVFRTFRIFITDVDNKKPILTIHRLTLQKEDSQLITLLEL-TVEDSDTPDDLILF 1574
Query: 1432 VITSPPRYGQIEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRTE 1491
IT P +G+I Y P+T F++ D+ + Y H T + D F +++G T+
Sbjct: 1575 TITQVPMHGKILY--NGSRPVTTFTKQDLNKNLISYKHDGSET-TEDSFSLTVTDGTHTD 1631
Query: 1492 H-------------GVFEITLETVDRALPVVTRNKGL----RLAQGAVG-LLSPDLLQLT 1533
V + + ++D LP +T N+G RL G +G L++ L+
Sbjct: 1632 FYVLPDTALATHKPQVMRVQIRSLDNRLPQITTNRGAPALKRLHTGHMGFLITSKSLKAE 1691
Query: 1534 DPDTPAENLTFLLVQLPQHGQLYLWGTGLLQHN-FTQQDVDSKNVAY-RHSGGDSQTDCF 1591
D D+P L + + + P+HG + G G FTQ D+D ++Y + G ++ D F
Sbjct: 1692 DQDSPHRLLKYKVTRGPEHGFIIKTGLGNQSTRVFTQADIDEMKISYVLNEGSNASKDIF 1751
Query: 1592 TFMATDG-----TNQGFIVNGR-VWEEPVLFTIQVDQLDKTAPRITLLHSPSQVGLLKNG 1645
F D TNQ F +N + E + + D T L +V L + G
Sbjct: 1752 YFSVEDNGGNKLTNQPFHLNWAWICLEKEYYIVDEDS--------TFL----EVTLTRRG 1799
Query: 1646 CYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHEKFSQKDLNSKTIL 1705
G TS + + +T FK + TT + + +
Sbjct: 1800 YLGE--TSFISIGTKDETAKKDKDFKWKTNKQIQFNPGQTTATWRVRIIPDNEYETSETF 1857
Query: 1706 YII--NPSLEVNS--DTVEFQIMDPTGNSATPQILELKWSHIEWSQTEYEVCENVGLLPL 1761
II P + V + +I+DP G+ +T I E EY++ E++G L +
Sbjct: 1858 QIILSEPLMAVLEFPEMATVEIVDP-GDESTVYIPE----------AEYKIEEDIGELLI 1906
Query: 1762 EIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPS----------KLIQFDPGMSTKMWNI 1811
+ R G + V Q SA TV+ S ++ FD + K +
Sbjct: 1907 PVRRSGDASQELIVICSTRQGSATGTISSTVLFSDYISRPEDHTSILHFDKNETQKTCQV 1966
Query: 1812 AITYDGLEEDDEVFEVILNSPVNAVLGTK---TKAAV-------KILDSKGGQCHPSYSS 1861
I D L E++E F V L PV LG + TK + +L + H + S+
Sbjct: 1967 LIIDDSLYEEEESFSVSLRLPVGGQLGARFPTTKVTILADRYDEPVLHFGDAEYHVNESA 2026
Query: 1862 NQSKHSTWEKG 1872
+ W +G
Sbjct: 2027 RYVEVCVWRRG 2037
Score = 210 bits (535), Expect = 1e-53
Identities = 316/1437 (21%), Positives = 568/1437 (39%), Gaps = 212/1437 (14%)
Query: 504 HSIRHKFPINVLPKDDSPPFLITNVVIELEEGQTILIQGSMLRASDVDASDDYIFFNITK 563
+S+ F + + P D+ PP +TN + EG + + + L +D D D I F + +
Sbjct: 812 NSVPGTFTLFLQPVDNQPPE-VTNRGFAILEGGSFNLSSNELHVTDPDTDIDQIVFILVR 870
Query: 564 PPQAGEIMKKPGPGLIGYPVHGFLQRDLFNGIIYYRHFGGEIF-EDSFQFVLWDSHEPPN 622
PQ G + + P F+Q D+ NG + Y+H + D+F + D
Sbjct: 871 GPQHGHLQYFKRCMV---PGESFMQADVINGSVSYQHGRDQTTTSDTFHLEVSDGVHHIP 927
Query: 623 LSVPQVATIHITP-VDDQLPKEAPGVSRHLVVK----ETEVAYITKKQLHFIDSESYDRE 677
+++P I + P V ++ P+ + S L V E + IT +H + D
Sbjct: 928 ITIP----ISVHPNVANRSPRISLRSSSLLDVSIDVLENKATEITMGVIHGKRKDVGDLM 983
Query: 678 LVYTITTPPFFSFSHRHLDAGKLFMVDSIPKVVKNPTALELRSFTQHAVNYMKVAYMPPM 737
L + + P +V+ +P FTQ + +VAY
Sbjct: 984 LSFIVKDSPKLG----------TILVNGLPT----------ERFTQEDLINGRVAYAHTA 1023
Query: 738 QDIGPHCRDVQFTFSVSNQH------GGTLHGICFNITILPVDNQVPEAFTNP-LKVTEG 790
++G + F+ +S + + +T+LPVDN P+ F V EG
Sbjct: 1024 GEVGFQKQHDAFSLILSKDSYQWVVGNSIIEKVQVQVTVLPVDNVGPKVFVGESFIVYEG 1083
Query: 791 GQSIISTEHILISDADTKLDNIDLSLRELPLHGRVE----LNGFPLNSGGT----FSWGD 842
++ ++ +H+ + D DT D + ++ P G +E G ++ G+ FS D
Sbjct: 1084 EKNSLTLQHLHVEDVDTHQDELLCTVTSQPASGYLEKIASAPGSKMSQSGSPISAFSLRD 1143
Query: 843 LHTLKVRYQ---HDGTEVLQDDLLLEVTDGTN-SAEFVLHVEVFPVNDEPPVLKADLMPV 898
+ + Y H G E +D +DG N S + + P NDE P L A V
Sbjct: 1144 IQVRHINYVQSIHKGVEPQEDQFTFYCSDGINFSPNVFFPIIILPTNDEQPKLFAHEFKV 1203
Query: 899 MNCSEGGEVVITSEYIFATDVDSDNLKLMFVIAREPQHGVVRRAGVTVDQ----FSQRDV 954
+ EG +VI ++ + D D +L F + P+HG + + T Q F+ +++
Sbjct: 1204 L---EGMSLVIDTQLLNGADADLPPNELHFQLTALPRHGRIIQQLATGSQPIHSFTLKEI 1260
Query: 955 I-SEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVNGCCYNGPNPSVPLHASFPVYDL 1013
+ + Y+H E D+ + +SDG+ H P
Sbjct: 1261 QEASTIVYEHDDSETKE----DSFEVWLSDGKH----------------TTHRKVP---- 1296
Query: 1014 NITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYL 1073
I V VD++ P + + V++G S +T L ATD D+ L FVL S PQ G L
Sbjct: 1297 -IVVTLVDDETPHLTVNNGLKVEKGHSEIITNRILKATDLDSDDKSLSFVLHSGPQQGLL 1355
Query: 1074 ENILPSVGFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSL 1133
+ + G ++N+ + ++ F ++N I Y+ H E D VTDG +
Sbjct: 1356 QRLRKPRGEVRNNLTLGMN-FTQDEINRGLICYI---HTGQEGIVDIIKFDVTDGVNTLT 1411
Query: 1134 EIPFSIIINPTNDEAPDFVVQNITVCEGQMKELDSSIISAVDLDIPQDALLFSITQKPRH 1193
+ F + I + P+ + + IT+ EG L +++++ D++ D FSIT+ P
Sbjct: 1412 DHYFYVTIGNLDSVFPEVISKRITLIEGARVTLTNNLLTNSDIN-SSDEHHFSITRAPSL 1470
Query: 1194 GLLIDRGFSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMH-DDSESLADDFTIQ 1252
G L ++ + P+ SF+ +L +++Y+H + E D F Q
Sbjct: 1471 GHLESSDYAGE---------------PIASFT-QLQLASNKISYVHTSNDEKKMDSFEFQ 1514
Query: 1253 LSDGKHKILKTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIY 1312
+ + + +T + + V+++KP+L+ + + ++++I+ L+ D D+P + I
Sbjct: 1515 VIGELYPVFRTFRIFITDVDNKKPILTIH-RLTLQKEDSQLITLLELTVEDSDTPDDLIL 1573
Query: 1313 YVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNLLRYTHTGAMDSQNQDSFTFYLW 1372
+ ++P +G++ R P T+++++ NL+ Y H G+ +DSF+ +
Sbjct: 1574 FTITQVPMHGKILYNGSR------PVTTFTKQDLNKNLISYKHDGS--ETTEDSFSLTVT 1625
Query: 1373 DGNN--------------RSPALDCQITIKDMEKGDIVILTKPLVVSK---GDRGFLTTT 1415
DG + + + QI D I + + G GFL T+
Sbjct: 1626 DGTHTDFYVLPDTALATHKPQVMRVQIRSLDNRLPQITTNRGAPALKRLHTGHMGFLITS 1685
Query: 1416 TLLAVDGTDKPEELL-YVITSPPRYGQIEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVT 1474
L + D P LL Y +T P +G I F+Q D+ + Y
Sbjct: 1686 KSLKAEDQDSPHRLLKYKVTRGPEHGFIIKTGLGNQSTRVFTQADIDEMKISY------- 1738
Query: 1475 VSSDRFRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGLRLAQGAVGLLSPDLLQLTD 1534
+++ G +F ++E N G +L L + +
Sbjct: 1739 --------VLNEGSNASKDIFYFSVED----------NGGNKLTNQPFHLNWAWICLEKE 1780
Query: 1535 PDTPAENLTFLLVQLPQHGQLYLWGTGLLQHNFTQQDVDSKNVAYRHSGGDSQTDCFTFM 1594
E+ TFL V L + G YL T + T+ + K+ ++ ++ F
Sbjct: 1781 YYIVDEDSTFLEVTLTRRG--YLGETSFISIG-TKDETAKKDKDFKWK--TNKQIQFNPG 1835
Query: 1595 ATDGTNQGFIVNGRVWEEPVLFTIQVDQLDKTAPRITLLHSPSQ--VGLLKNGCYG-IYI 1651
T T + I+ +E F I + + P + +L P V ++ G +YI
Sbjct: 1836 QTTATWRVRIIPDNEYETSETFQIILSE-----PLMAVLEFPEMATVEIVDPGDESTVYI 1890
Query: 1652 TSRVLKASDP------------DTEDDQIIF-KILQGPKHGHLENTTT-GEFIHEK---- 1693
K + D + I+ QG G + +T ++I
Sbjct: 1891 PEAEYKIEEDIGELLIPVRRSGDASQELIVICSTRQGSATGTISSTVLFSDYISRPEDHT 1950
Query: 1694 ----FSQKDLNSKTILYIINPSLEVNSDTVEFQIMDPTGNSATPQ-------ILELKWSH 1742
F + + + II+ SL ++ + P G + IL ++
Sbjct: 1951 SILHFDKNETQKTCQVLIIDDSLYEEEESFSVSLRLPVGGQLGARFPTTKVTILADRYDE 2010
Query: 1743 --IEWSQTEYEVCENVGLLPLEIIRRGYSMDS----AFVGIKVNQVSAAVGKDFTVIPSK 1796
+ + EY V E+ + + + RRG + A K Q SA G D+ I S+
Sbjct: 2011 PVLHFGDAEYHVNESARYVEVCVWRRGTDLSQPSSIAVRSRKSEQESAEAGTDYVGI-SR 2069
Query: 1797 LIQFDPGMSTKMWNIAITYDGLE---EDDEVFEVILNSPVNAVLGTKTKAAVKILDS 1850
+ F PG+ + + + I D + E E FE++L P+ AVLG K + I D+
Sbjct: 2070 NLDFAPGVRMQTFQVTILDDLGQPTLEGPEKFELLLQMPMGAVLGEPNKTTIFIEDT 2126
>gi|108773804 Fraser syndrome 1 [Homo sapiens]
Length = 4011
Score = 525 bits (1352), Expect = e-148
Identities = 452/1608 (28%), Positives = 730/1608 (45%), Gaps = 128/1608 (7%)
Query: 315 LTTSVLDCEEDETPKPLLVFNITKAPLQGYVTHLLDHTRPIS-----SFTWKDLSDMQIA 369
L S+L+ ++ E L+F++ P G + L + + + F+WKD+++ ++
Sbjct: 1120 LDFSLLNVQDQEGRVEDLLFHVVSTPTNGQLV-LSRNGKEVQLDKAGRFSWKDVNEKKVR 1178
Query: 370 YQPPNSSHSERRHDEVELEVYD--FFFERSAPMTVHISIRTADTNAPRVSWNTGLSLLEG 427
+ S + R + L++ D FF E I+I+ T AP V N L + G
Sbjct: 1179 FV---HSKEKLRKGYLFLKISDQQFFSEPQL-----INIQAFSTQAPYVLRNEVLHISRG 1230
Query: 428 QSRAITWEQFQVVDNDDIGAVRLVTVGGLQHGWL--TLRGGKG--FLFTVADLQAGVVRY 483
+ IT + + D+D+ V + + HG L TL+ + F + +L G++ Y
Sbjct: 1231 ERATITTQMLDIRDDDNPQDVVIEIIDPPLHGQLLQTLQSPATPIYQFQLDELSRGLLHY 1290
Query: 484 HHDDSDSTKDFVVFRIFDGHHSIRHKFPINVLPKDDSPPFLITNVVIELEEGQTILIQGS 543
HD SDST D V + DGH F + +P++D L+ N ++ + EG + I
Sbjct: 1291 AHDGSDSTSDVAVLQANDGHSFHNILFQVKTVPQNDRGLQLVANSMVWVPEGGMLQITNR 1350
Query: 544 MLRASDVDASDDYIFFNITKP-PQAGEI-----MKKPGP---------GLIGYPVHGFLQ 588
+L+A AS + I + IT+ PQ GE+ M P G P F Q
Sbjct: 1351 ILQAEAPGASAEEIIYKITQDYPQFGEVVLLVNMPADSPADEGQHLPDGRTATPTSTFTQ 1410
Query: 589 RDLFNGIIYYRHFGGEIFEDSFQFVLWDSHEPPNLSVPQVATIHITPVDDQLPKEAPGVS 648
+D+ GI++YRH G DSF+F + + + I I P + PK + S
Sbjct: 1411 QDINEGIVWYRHSGAPAQSDSFRFEVSSASNAQTRLESHMFNIAILPQTPEAPKVSLEAS 1470
Query: 649 RHLVVKETEVAYITKKQLHFIDSESYDRELVYTITTPPFFSFSHRHLDAGKLFMVDSIPK 708
H+ +E + I L FI+SE ++VY IT P H + G + D
Sbjct: 1471 LHMTAREDGLTVIQPHSLSFINSEKPSGKIVYNITLP-------LHPNQGIIEHRD---- 1519
Query: 709 VVKNPTALELRSFTQHAVNYMKVAYMPPMQDIGPHCRD------------VQFTFSVSN- 755
+P + +R FTQ +N KV Y PP PH ++ V+F F+VS+
Sbjct: 1520 ---HPHS-PIRYFTQEDINQGKVMYRPP--PAAPHLQELMAFSFAGLPESVKFHFTVSDG 1573
Query: 756 QHGGTLHGICFNITILPVDNQVP--EAFTNPLKVTEGGQSIISTEHILISDADTKLDNID 813
+H T + I +LP D Q+P + L V+ GG + + + +++ DA+T +
Sbjct: 1574 EH--TSPEMVLTIHLLPSDQQLPVFQVTAPRLAVSPGGSTSVGLQ-VVVRDAETAPKELF 1630
Query: 814 LSLRELPLHGRVELNGF----PLNSGGTFSWGDLHTLKVRYQHDGTEVLQDDLLLEVTDG 869
LR P HG + + P+ +G TF++ D+ ++Y HDG+ +D + + VTDG
Sbjct: 1631 FELRRPPQHGVLLKHTAEFRRPMATGDTFTYEDVEKNALQYIHDGSSTREDSMEISVTDG 1690
Query: 870 TNSAEFVLHVEVFPVNDEPPVLKADLMPVMNCSEGGEVVITSEYIFATDVDSDNLKLMFV 929
+ VEV D P L A + + +IT ++ D S + ++
Sbjct: 1691 LTVTMLEVRVEVSLSEDRGPRLAAGSSLSITVASKSTAIITRSHLAYVDDSSPDPEIWIQ 1750
Query: 930 IAREPQHGVVRR-AGVTVDQFSQRDVISEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGP 988
+ P +G + R +G V++ S+ +S +I F+T +V+D
Sbjct: 1751 LNYLPSYGTLLRISGSEVEELSE---VSNFTMEDINNKKIRYSAVFETDGHLVTDS---- 1803
Query: 989 FVNGCCYNGPNPSVPLHASFPVYDLNITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHL 1048
Y + H ++ + IT P +N PP IA + VDEG L+ +H
Sbjct: 1804 -----FYFSVSDMDHNHLDNQIFTIMIT--PAENPPPVIAFADLITVDEGGRAPLSFHHF 1856
Query: 1049 SATDPDTAAD-DLEFVLVSPPQFGYLENILPSVGFEKSNIGISIDSFQWKDMNAFHINYV 1107
ATD D D L + P++G +EN F SF +D+ +I Y
Sbjct: 1857 FATDDDDNLQRDAIIKLSALPKYGCIENTGTGDRFGPETASDLEASFPIQDVLENYIYYF 1916
Query: 1108 QSRHLRIEPTADQFTVYVTDGKHHSLEIPFSIIINPTNDEAPDFVVQNITVCEGQMKELD 1167
QS H IEPT D F+ YV+DG S +I I NDE P +Q + V +
Sbjct: 1917 QSVHESIEPTHDIFSFYVSDGTSRSEIHSINITIERKNDEPPRMTLQPLRVQLSSGVVIS 1976
Query: 1168 SSIISAVDLDIPQDALLFSITQKPRHGLLIDRGFSKDFSENKQPANPHQKHAPVHSFSME 1227
+S +S DLD P + L+F +T+KP HG ++ R + + EN + +F+ +
Sbjct: 1977 NSSLSLQDLDTPDNELIFVLTKKPDHGHVLWRQTASEPLENGRVL------VQGSTFTYQ 2030
Query: 1228 LLKTGMRLTYMHDDSESLADDFTIQLSDGKHKILKTISVEVIPVNDEKPMLSKKAEIAMN 1287
+ G+ + Y+ + D+F L+DG H + + + P L+ + ++
Sbjct: 2031 DILAGL-VGYVPSVPGMVVDEFQFSLTDGLHVDTGRMKIYTELPASDTPHLAINQGLQLS 2089
Query: 1288 MGETRIISSAILSAIDEDSPREKIYYVFERLPQNGQLQLKIGRDWVPLS---PGMKCTQE 1344
G I+ L D DS ++ Y+ + P G+LQ+ + +S P TQ
Sbjct: 2090 AGSVARITEQHLKVTDIDSDDHQVMYIMKEDPGAGRLQMMKHGNLEQISIKGPIRSFTQA 2149
Query: 1345 EVDLNLLRYTHTGAMDSQNQDSFTFYLWDGN-NRSPALDCQITIKDMEKGDIVILTKPLV 1403
++ Y+H G + +F F + DG NR I+I + + ++ K LV
Sbjct: 2150 DISQGQPEYSH-GTGEPGGSFAFKFDVVDGEGNRLIDKSFSISILEDKSPPVITTNKGLV 2208
Query: 1404 VSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYGQIEYVHYPGVPITNFSQMDVVGQ 1463
+ + +TT L A D P EL+Y IT P+ G +E+ PG+ I++F+Q D+ +
Sbjct: 2209 LDENSVKKITTLQLSATDQDSGPTELIYRITRQPQLGHLEHAASPGIQISSFTQADLTSR 2268
Query: 1464 TVCYVHKSKVTVSSDRFRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGLRLAQGAVG 1523
V YVH S+ SD F F +S+G+ F ITL VD +LPVV +N G+R+ +G
Sbjct: 2269 NVQYVHSSEAEKHSDAFSFTLSDGVSEVTQTFHITLHPVDDSLPVV-QNLGMRVQEGMRK 2327
Query: 1524 LLSPDLLQLTDPDTPAENLTFLLVQLPQHGQLYLWGTGL---LQHNFTQQDVDSKNVAYR 1580
++ L+ D DT AE++TF +VQ P+HG + G L FT +D+ V+Y
Sbjct: 2328 TITEFELKAVDADTEAESVTFTIVQPPRHGTIERTSNGQHFHLTSTFTMKDIYQNRVSYS 2387
Query: 1581 HSGGDSQTDCFTFMATDGTNQGFIV--NGR--VWEEPVLFTIQVDQLDKTAPRITLLHSP 1636
H G +S D FTF +DGTN FI+ G+ + P F + + +D PRI
Sbjct: 2388 HDGSNSLKDRFTFTVSDGTNPFFIIEEGGKEIMTAAPQPFRVDILPVDDGTPRIV----- 2442
Query: 1637 SQVGL----LKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHE 1692
+ +GL +G IT + L DPDTED Q++++I GPKHG +EN
Sbjct: 2443 TNLGLQWLEYMDGKATNLITKKELLTMDPDTEDAQLVYEITTGPKHGFVENKLQPGRAAA 2502
Query: 1693 KFSQKDLNSKTILYIIN-PSLEVNSDTVEFQIMDPTGNSATPQILELKWSHIEWSQTEYE 1751
F+Q+D+N I Y+++ + D+ +F + D N + + ++WS I + T Y
Sbjct: 2503 TFTQEDVNLGLIRYVLHKEKIREMMDSFQFLVKDSKPNVVSDNVFHIQWSLISFKYTSYN 2562
Query: 1752 VCENVGLLPLEIIRRGYSMDSAFVGIKVNQ--------VSAAVGKDFTVIPSKLIQFDPG 1803
V E G + + + R G A V + Q VS+ G+ V + +QFD
Sbjct: 2563 VSEKAGSVSVTVQRTGNLNQYAIVLCRTEQGTASSSSRVSSQPGQQDYVEYAGQVQFDER 2622
Query: 1804 MSTKMWNIAITYDGLEEDDEVFEVILNSPVNAVLGTKTKAAVKILDSK 1851
TK I I D + E+ E F V L+ P A+LG T+A V I D++
Sbjct: 2623 EDTKSCTIVINDDDVFENVESFTVELSMPAYALLGEFTQAKVIINDTE 2670
Score = 133 bits (334), Expect = 2e-30
Identities = 190/772 (24%), Positives = 315/772 (40%), Gaps = 108/772 (13%)
Query: 1025 PSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSVGFEK 1084
PS+ + ++ G L + L+ D + +DL F +VS P G L +L G E
Sbjct: 1102 PSLHVNGSLILPIGSIKPLDFSLLNVQDQEGRVEDLLFHVVSTPTNGQL--VLSRNGKE- 1158
Query: 1085 SNIGISIDS---FQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLEIPFSIII 1141
+ +D F WKD+N + +V S+ + + ++D + S P I I
Sbjct: 1159 ----VQLDKAGRFSWKDVNEKKVRFVHSKE---KLRKGYLFLKISDQQFFS--EPQLINI 1209
Query: 1142 NPTNDEAPDFVVQN--ITVCEGQMKELDSSIISAVDLDIPQDALLFSITQKPRHGLLIDR 1199
+ +AP +V++N + + G+ + + ++ D D PQD ++ I P HG L+
Sbjct: 1210 QAFSTQAP-YVLRNEVLHISRGERATITTQMLDIRDDDNPQDVVI-EIIDPPLHGQLL-- 1265
Query: 1200 GFSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFTIQLSDGK-- 1257
+ PA P++ F ++ L G+ L Y HD S+S +D +Q +DG
Sbjct: 1266 ------QTLQSPA------TPIYQFQLDELSRGL-LHYAHDGSDSTSDVAVLQANDGHSF 1312
Query: 1258 HKILKTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSA-IDEDSPREKIYYVFE 1316
H IL V+ +P ND L + + + G I++ IL A S E IY + +
Sbjct: 1313 HNIL--FQVKTVPQNDRGLQLVANSMVWVPEGGMLQITNRILQAEAPGASAEEIIYKITQ 1370
Query: 1317 RLPQNGQLQLKIGR-------------DWVPLSPGMKCTQEEVDLNLLRYTHTGAMDSQN 1363
PQ G++ L + D +P TQ++++ ++ Y H+GA
Sbjct: 1371 DYPQFGEVVLLVNMPADSPADEGQHLPDGRTATPTSTFTQQDINEGIVWYRHSGA--PAQ 1428
Query: 1364 QDSFTFYLWDGNNRSPALDCQI----TIKDMEKGDIVILTKPLVVSKGDRGF-LTTTTLL 1418
DSF F + +N L+ + + + V L L ++ + G + L
Sbjct: 1429 SDSFRFEVSSASNAQTRLESHMFNIAILPQTPEAPKVSLEASLHMTAREDGLTVIQPHSL 1488
Query: 1419 AVDGTDKPE-ELLYVITSP--PRYGQIEYVHYPGVPITNFSQMDVVGQTVCY------VH 1469
+ ++KP +++Y IT P P G IE+ +P PI F+Q D+ V Y H
Sbjct: 1489 SFINSEKPSGKIVYNITLPLHPNQGIIEHRDHPHSPIRYFTQEDINQGKVMYRPPPAAPH 1548
Query: 1470 KSKVTV-------SSDRFRFIISNGLRTE-HGVFEITLETVDRALPVVTRNKGLRLAQGA 1521
++ S +F F +S+G T V I L D+ LPV + RLA
Sbjct: 1549 LQELMAFSFAGLPESVKFHFTVSDGEHTSPEMVLTIHLLPSDQQLPVF-QVTAPRLAVSP 1607
Query: 1522 VGLLSPDL-LQLTDPDTPAENLTFLLVQLPQHGQLYL--------WGTGLLQHNFTQQDV 1572
G S L + + D +T + L F L + PQHG L TG FT +DV
Sbjct: 1608 GGSTSVGLQVVVRDAETAPKELFFELRRPPQHGVLLKHTAEFRRPMATG---DTFTYEDV 1664
Query: 1573 DSKNVAYRHSGGDSQTDCFTFMATDGTNQGFIVNGRVWEEPVLFTIQVDQLDKTAPRITL 1632
+ + Y H G ++ D TDG + ++V + PR+
Sbjct: 1665 EKNALQYIHDGSSTREDSMEISVTDGLTVTMLE----------VRVEVSLSEDRGPRLAA 1714
Query: 1633 LHSPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIH- 1691
S S K+ IT L D + D +I ++ P +G L + E
Sbjct: 1715 GSSLSITVASKSTA---IITRSHLAYVDDSSPDPEIWIQLNYLPSYGTLLRISGSEVEEL 1771
Query: 1692 ---EKFSQKDLNSKTILY--IINPSLEVNSDTVEFQIMDPTGNSATPQILEL 1738
F+ +D+N+K I Y + + +D+ F + D N QI +
Sbjct: 1772 SEVSNFTMEDINNKKIRYSAVFETDGHLVTDSFYFSVSDMDHNHLDNQIFTI 1823
Score = 111 bits (277), Expect = 9e-24
Identities = 97/339 (28%), Positives = 153/339 (45%), Gaps = 34/339 (10%)
Query: 305 LEVDQFILTSLTTSVLDCEEDETPKPLLVFNITKAPLQGYVTHLLDHTRPISSFTWKDLS 364
L +D+ + +TT L + ++ L++ IT+ P G++ H ISSFT DL+
Sbjct: 2207 LVLDENSVKKITTLQLSATDQDSGPTELIYRITRQPQLGHLEHAASPGIQISSFTQADLT 2266
Query: 365 DMQIAYQPPNSSHSERRHDEVELEVYDFFFERSAPMTVHISIRTADTNAPRVSWNTGLSL 424
+ Y +SS +E+ D + D E T HI++ D + P V N G+ +
Sbjct: 2267 SRNVQY--VHSSEAEKHSDAFSFTLSDGVSE--VTQTFHITLHPVDDSLPVVQ-NLGMRV 2321
Query: 425 LEGQSRAITWEQFQVVDND-DIGAVRLVTVGGLQHGWL-TLRGGKGF----LFTVADLQA 478
EG + IT + + VD D + +V V +HG + G+ F FT+ D+
Sbjct: 2322 QEGMRKTITEFELKAVDADTEAESVTFTIVQPPRHGTIERTSNGQHFHLTSTFTMKDIYQ 2381
Query: 479 GVVRYHHDDSDSTKDFVVFRIFDGHH--------------SIRHKFPINVLPKDDSPPFL 524
V Y HD S+S KD F + DG + + F +++LP DD P +
Sbjct: 2382 NRVSYSHDGSNSLKDRFTFTVSDGTNPFFIIEEGGKEIMTAAPQPFRVDILPVDDGTPRI 2441
Query: 525 ITNVVIE----LEEGQTILIQGSMLRASDVDASDDYIFFNITKPPQAGEIMKKPGPGLIG 580
+TN+ ++ ++ T LI L D D D + + IT P+ G + K PG
Sbjct: 2442 VTNLGLQWLEYMDGKATNLITKKELLTMDPDTEDAQLVYEITTGPKHGFVENKLQPGRAA 2501
Query: 581 YPVHGFLQRDLFNGIIYYRHFGGEIFE--DSFQFVLWDS 617
F Q D+ G+I Y +I E DSFQF++ DS
Sbjct: 2502 AT---FTQEDVNLGLIRYVLHKEKIREMMDSFQFLVKDS 2537
Score = 49.3 bits (116), Expect = 4e-05
Identities = 37/116 (31%), Positives = 59/116 (50%), Gaps = 8/116 (6%)
Query: 1743 IEWSQTEYEVCENVG-----LLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKL 1797
IE+ + Y+V E G +L +++IRRG ++ V SA G D+ S++
Sbjct: 3041 IEFEEAAYQVREPAGPDAIAILNIKVIRRGDQNRTSKVRCSTRDGSAQSGVDYYP-KSRV 3099
Query: 1798 IQFDPGMSTKMWNIAITYDGLEEDDEVFEVIL--NSPVNAVLGTKTKAAVKILDSK 1851
++F PG+ + + I + E E F ++L + PV AVLG T A V ILD +
Sbjct: 3100 LKFSPGVDHIFFKVEILSNEDREWHESFSLVLGPDDPVEAVLGDVTTATVTILDQE 3155
>gi|47419930 chondroitin sulfate proteoglycan 4 [Homo sapiens]
Length = 2322
Score = 192 bits (489), Expect = 2e-48
Identities = 329/1385 (23%), Positives = 555/1385 (40%), Gaps = 188/1385 (13%)
Query: 395 ERSAPMTVHISIRTADTNAPRVSWNTGLSLLEGQSRAITWEQFQVVDN---DDIGAVRLV 451
+ S P T+ + A A ++ +TGL L +G + I V N D+ + V
Sbjct: 647 QASPPATLKV---VAIRPAIQIHRSTGLRLAQGSAMPILPANLSVETNAVGQDVSVLFRV 703
Query: 452 TVGGLQHGWLTLRGGKGF---------LFTVADLQAGVVRYHHDDSD----STKDFVVFR 498
T G LQ G L +G G F D++ G VRY D T + +
Sbjct: 704 T-GALQFGELQKQGAGGVEGAEWWATQAFHQRDVEQGRVRYLSTDPQHHAYDTVENLALE 762
Query: 499 IFDGHHSIRH-KFPINVLPKDDSPPFLITNVVIELEEGQTILIQGSMLRASDVDA----- 552
+ G + + FP+ + T ++ LE T Q L + ++A
Sbjct: 763 VQVGQEILSNLSFPVTIQRA--------TVWMLRLEPLHTQNTQQETLTTAHLEATLEEA 814
Query: 553 --SDDYIFFNITKPPQAGEIMKKPGPGLIGYPVHGFLQRDLFNGIIYYRHFG--GEIFED 608
S + + + P+ G + + G GF Q D+ G + Y E ED
Sbjct: 815 GPSPPTFHYEVVQAPRKGNLQLQ---GTRLSDGQGFTQDDIQAGRVTYGATARASEAVED 871
Query: 609 SFQFVLWDSHEPPNLSVPQVATIHITPVDDQLPKEAPGVSRHL-VVKETEVAYITKKQLH 667
+F+F + PP S IHI D AP ++ L VV E ++ L
Sbjct: 872 TFRFRVT---APPYFSPLYTFPIHIGGDPD-----APVLTNVLLVVPEGGEGVLSADHLF 923
Query: 668 F--IDSESYDRELVYTITTPPFFSFSHRHLDAGKLFMVDSIPKVVKNPTALELRSFTQHA 725
++S SY +Y + P RH G+L + K + SFT
Sbjct: 924 VKSLNSASY----LYEVMERP------RH---GRLAWRGTQDKTTM------VTSFTNED 964
Query: 726 VNYMKVAYMPPMQDIGPHCRDVQFTFSVSNQHGGTL-----HGICFNITILPVDNQVP-E 779
+ ++ Y + D+ F + + G + G+ F + I PV++ P +
Sbjct: 965 LLRGRLVYQHDDSETTED--DIPFVATRQGESSGDMAWEEVRGV-FRVAIQPVNDHAPVQ 1021
Query: 780 AFTNPLKVTEGGQSIISTEHILISDADTKLDNIDLSL-RELPLHGRVELNGFPLNSGGTF 838
+ V GG+ +++T+ + SDAD+ + L L R+ L G + P F
Sbjct: 1022 TISRIFHVARGGRRLLTTDDVAFSDADSGFADAQLVLTRKDLLFGSIVAVDEPTRPIYRF 1081
Query: 839 SWGDLHTLKVRYQHDGTEVLQDDLLLEVTDGTNSAEFVLHVEVFPVNDEPPVLKADLMPV 898
+ DL +V + H G + + + L+V+DG + A +L V+ P L+
Sbjct: 1082 TQEDLRKRRVLFVHSGAD--RGWIQLQVSDGQHQATALLEVQA-----SEPYLRVANGSS 1134
Query: 899 MNCSEGGEVVITSEYIFAT---DVDSDNLKLMFVIAREPQHGVVRRAGVTVDQFSQRDVI 955
+ +GG+ I + + D+ S + ++ + + P+ G + RAG FSQ+D++
Sbjct: 1135 LVVPQGGQGTIDTAVLHLDTNLDIRSGD-EVHYHVTAGPRWGQLVRAGQPATAFSQQDLL 1193
Query: 956 SEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVNGCCYNGPNPSVPLHASFPVYDLNI 1015
AV Y H G L P DT+ V EAGP + V + P+ L +
Sbjct: 1194 DGAVLYSHNG---SLSP-RDTMAFSV---EAGP-----VHTDATLQVTIALEGPLAPLKL 1241
Query: 1016 TVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGYLEN 1075
+ V +G + + + L A D+ F + SPP GYL
Sbjct: 1242 VRH------------KKIYVFQGEAAEIRRDQLEAAQEAVPPADIVFSVKSPPSAGYL-- 1287
Query: 1076 ILPSVGFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHSLE- 1134
++ S G ++ S+D Q A V H R E +D F++ V G LE
Sbjct: 1288 VMVSRG-ALADEPPSLDPVQSFSQEAVDTGRVLYLHSRPEAWSDAFSLDVASGLGAPLEG 1346
Query: 1135 IPFSIIINPTNDEAPDFVVQNITVCEGQMKELDSSIISAVDLDIPQ-DALLFSITQKPRH 1193
+ + + P A QN +V EG L ++ P L + + P+H
Sbjct: 1347 VLVELEVLPA---AIPLEAQNFSVPEGGSLTLAPPLLRVSGPYFPTLLGLSLQVLEPPQH 1403
Query: 1194 GLLIDRGFSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFTI-- 1251
G L ++ P + + +FS +++ + + Y+HD SE+L D F +
Sbjct: 1404 GAL------------QKEDGPQAR--TLSAFSWRMVEEQL-IRYVHDGSETLTDSFVLMA 1448
Query: 1252 ---QLSDGKHKILKTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPR 1308
++ H + T++ V+PVND+ P+L+ + M G T I + L + D DS
Sbjct: 1449 NASEMDRQSHPVAFTVT--VLPVNDQPPILTTNTGLQMWEGATAPIPAEALRSTDGDSGS 1506
Query: 1309 EKIYYVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNLLRYTHTGAMDSQNQDSFT 1368
E + Y E+ P NG++ L+ P + TQ ++D L+ ++H G +D F
Sbjct: 1507 EDLVYTIEQ-PSNGRVVLR----GAPGTEVRSFTQAQLDGGLVLFSHRGTLDG----GFR 1557
Query: 1369 FYLWDGNNRSPALDCQITIKDMEKGDIVIL--TKPLVVSKGDRGFLTTTTLLAVD--GTD 1424
F L DG + SP ++T +K ++ L ++ L V G L++ TL A GTD
Sbjct: 1558 FRLSDGEHTSPGHFFRVT---AQKQVLLSLKGSQTLTVCPGSVQPLSSQTLRASSSAGTD 1614
Query: 1425 KPEELLYVITSPPRYGQIEYVHY--PGVPITNFSQMDVVGQTVCYVHK---SKVTVSSDR 1479
P+ LLY + P+ G++ + G + NF+Q +V + Y H+ + D
Sbjct: 1615 -PQLLLYRVVRGPQLGRLFHAQQDSTGEALVNFTQAEVYAGNILYEHEMPPEPFWEAHDT 1673
Query: 1480 FRFIISNGLRTEHGVFEITLETVDRALPV----VTRNKGLRLAQG-----AVGLLSPD-- 1528
+S+ + + + A P + +NKGL + +G V L
Sbjct: 1674 LELQLSSPPARDVAATLAVAVSFEAACPQRPSHLWKNKGLWVPEGQRARITVAALDASNL 1733
Query: 1529 LLQLTDPDTPAENLTFLLVQLPQHGQLYLWGTGLL--QHNFTQQDVDSKNVAYRHSGGDS 1586
L + P ++ F + Q P GQL + L Q +F Q + + + Y H GG +
Sbjct: 1734 LASVPSPQRSEHDVLFQVTQFPSRGQLLVSEEPLHAGQPHFLQSQLAAGQLVYAHGGGGT 1793
Query: 1587 QTDCFTFMATDGTNQGFIVNGRVWEEPVLFTIQVDQLDKTAPRITLLHSPSQVGLLKNGC 1646
Q D F F A G V G E F I V +++ P+ + V L
Sbjct: 1794 QQDGFHFRAHLQGPAGASVAGPQTSE--AFAITVRDVNERPPQ-----PQASVPLRLTRG 1846
Query: 1647 YGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHEKFSQKDLNSKTILY 1706
I+ L DPD+ +I +++ + P +G L G +F+Q D++S + +
Sbjct: 1847 SRAPISRAQLSVVDPDSAPGEIEYEVQRAPHNGFLSLVGGGLGPVTRFTQADVDSGRLAF 1906
Query: 1707 IINPS 1711
+ N S
Sbjct: 1907 VANGS 1911
Score = 176 bits (446), Expect = 2e-43
Identities = 303/1286 (23%), Positives = 510/1286 (39%), Gaps = 180/1286 (13%)
Query: 350 DHTRPISSFTWKDLSDMQIAYQPPNSSHSERRHDEVELEVYDFFFERSAPMT-------V 402
D T ++SFT +DL ++ YQ +S +E D++ V E S M
Sbjct: 952 DKTTMVTSFTNEDLLRGRLVYQHDDSETTE---DDIPF-VATRQGESSGDMAWEEVRGVF 1007
Query: 403 HISIRTADTNAPRVSWNTGLSLLEGQSRAITWEQ--FQVVDNDDIGAVRLVTVGGLQHGW 460
++I+ + +AP + + + G R +T + F D+ A ++T L G
Sbjct: 1008 RVAIQPVNDHAPVQTISRIFHVARGGRRLLTTDDVAFSDADSGFADAQLVLTRKDLLFGS 1067
Query: 461 LTLRGGKG---FLFTVADLQAGVVRYHHDDSDSTKDFVVFRIFDGHHSIRHKFPINVLPK 517
+ + FT DL+ V + H +D + ++ ++ DG H +
Sbjct: 1068 IVAVDEPTRPIYRFTQEDLRKRRVLFVHSGAD--RGWIQLQVSDGQHQATALLEVQA--- 1122
Query: 518 DDSPPFLIT---NVVIELEEGQTILIQGSMLRASDVDA-SDDYIFFNITKPPQAGEIMKK 573
S P+L + ++ + GQ + + +++D S D + +++T P+ G++++
Sbjct: 1123 --SEPYLRVANGSSLVVPQGGQGTIDTAVLHLDTNLDIRSGDEVHYHVTAGPRWGQLVRA 1180
Query: 574 PGPGLIGYPVHGFLQRDLFNGIIYYRHFGGEIFEDSFQFVLWDSHEPPNLSVPQVATIHI 633
G P F Q+DL +G + Y H G D+ F + V AT+ +
Sbjct: 1181 ------GQPATAFSQQDLLDGAVLYSHNGSLSPRDTMAFSVEAG------PVHTDATLQV 1228
Query: 634 TPVDDQLPKEAPGVSRH--LVVKETEVAYITKKQLHFIDSESYDRELVYTITTPPFFSFS 691
T + + P + RH + V + E A I + QL ++V+++ +PP
Sbjct: 1229 T-IALEGPLAPLKLVRHKKIYVFQGEAAEIRRDQLEAAQEAVPPADIVFSVKSPP----- 1282
Query: 692 HRHLDAGKLFMVDSIPKVVKNPTALELRSFTQHAVNYMKVAYMPPMQDIGPHCRDVQFTF 751
AG L MV + P+ ++SF+Q AV+ +V Y+ P F+
Sbjct: 1283 ----SAGYLVMVSRGALADEPPSLDPVQSFSQEAVDTGRVLYLHSR----PEAWSDAFSL 1334
Query: 752 SVSNQHGGTLHGICFNITILPVDNQVPEAFTNPLKVTEGGQSIISTEHILISDAD-TKLD 810
V++ G L G+ + +LP +P N V EGG ++ + +S L
Sbjct: 1335 DVASGLGAPLEGVLVELEVLPA--AIPLEAQN-FSVPEGGSLTLAPPLLRVSGPYFPTLL 1391
Query: 811 NIDLSLRELPLHGRVELNGFP-LNSGGTFSWGDLHTLKVRYQHDGTEVLQDDLLLEVTDG 869
+ L + E P HG ++ P + FSW + +RY HDG+E L D +L
Sbjct: 1392 GLSLQVLEPPQHGALQKEDGPQARTLSAFSWRMVEEQLIRYVHDGSETLTDSFVLMANAS 1451
Query: 870 T---NSAEFVLHVEVFPVNDEPPVLKADLMPVMNCSEGGEVVITSEYIFATDVDSDNLKL 926
S V V PVND+PP+L + + EG I +E + +TD DS + L
Sbjct: 1452 EMDRQSHPVAFTVTVLPVNDQPPILTTNTG--LQMWEGATAPIPAEALRSTDGDSGSEDL 1509
Query: 927 MFVIAREPQHGVVRRA--GVTVDQFSQRDVISEAVTYKHTGGEIGLMPCFDTITLVVSDG 984
++ I + VV R G V F+Q + V + H G G +SDG
Sbjct: 1510 VYTIEQPSNGRVVLRGAPGTEVRSFTQAQLDGGLVLFSHRGTLDG------GFRFRLSDG 1563
Query: 985 EAGPFVNGCCYNGPNPSVPLHASFPVY-----DLNITVYPVDNQPPSIAIGPVFVVDEGC 1039
E + P + A V +TV P QP S
Sbjct: 1564 E---------HTSPGHFFRVTAQKQVLLSLKGSQTLTVCPGSVQPLS------------- 1601
Query: 1040 STALTVNHLSATDPDTAADDLEFVLVSPPQFGYLENILPSVGFEKSNIGISIDSFQWKDM 1099
S L + + TDP L + +V PQ G L + ++ + G ++ +F ++
Sbjct: 1602 SQTLRASSSAGTDPQL----LLYRVVRGPQLGRLFHA------QQDSTGEALVNFTQAEV 1651
Query: 1100 NAFHINYVQSRHLRIEP---TADQFTVYVTDGKHHSLEIPFSIIIN--PTNDEAPDFVVQ 1154
A +I Y + EP D + ++ + ++ ++ + P + +
Sbjct: 1652 YAGNILY--EHEMPPEPFWEAHDTLELQLSSPPARDVAATLAVAVSFEAACPQRPSHLWK 1709
Query: 1155 N--ITVCEGQMKELDSSIISAVDL--DIP-----QDALLFSITQKPRHGLLIDRGFSKDF 1205
N + V EGQ + + + A +L +P + +LF +TQ P G L+
Sbjct: 1710 NKGLWVPEGQRARITVAALDASNLLASVPSPQRSEHDVLFQVTQFPSRGQLL-------- 1761
Query: 1206 SENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFTIQL--------SDGK 1257
+++P + Q H F L G +L Y H + D F + S
Sbjct: 1762 -VSEEPLHAGQPH-----FLQSQLAAG-QLVYAHGGGGTQQDGFHFRAHLQGPAGASVAG 1814
Query: 1258 HKILKTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPREKIYYVFER 1317
+ + ++ V VN+ P + + G IS A LS +D DS +I Y +R
Sbjct: 1815 PQTSEAFAITVRDVNERPPQPQASVPLRLTRGSRAPISRAQLSVVDPDSAPGEIEYEVQR 1874
Query: 1318 LPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNLLRYTHTGAMDSQNQDSFTFYLWDGNNR 1377
P NG L L G L P + TQ +VD L + G S F + DG
Sbjct: 1875 APHNGFLSLVGG----GLGPVTRFTQADVDSGRLAFVANG---SSVAGIFQLSMSDG--A 1925
Query: 1378 SPALDCQITIKDMEKGDIVILTKPLVVSKG-DRGFLTTTTLLAVDGTDKPEELLYVITSP 1436
SP L + + + V L PL V + R L+ L V ++P E Y +
Sbjct: 1926 SPPLPMSLAVDILPSAIEVQLRAPLEVPQALGRSSLSQQQLRVVSDREEP-EAAYRLIQG 1984
Query: 1437 PRYGQIEYVHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFI-ISNGLRTEHGVF 1495
P+YG ++ G P + FSQ + V + + + S D FR + ++ G+ V
Sbjct: 1985 PQYG---HLLVGGRPTSAFSQFQIDQGEVVFAF-TNFSSSHDHFRVLALARGVNAS-AVV 2039
Query: 1496 EITLETVDRALPVVTRNKGLRLAQGAVGLLSPDLLQLTDPDTPAENL-TFLLVQLPQHGQ 1554
+T+ RAL V G QGA L P +L + ++ F L++ P+HG+
Sbjct: 2040 NVTV----RALLHVW--AGGPWPQGATLRLDPTVLDAGELANRTGSVPRFRLLEGPRHGR 2093
Query: 1555 LYLW-------GTGLLQHNFTQQDVD 1573
+ G L FTQQD++
Sbjct: 2094 VVRVPRARTEPGGSQLVEQFTQQDLE 2119
Score = 148 bits (374), Expect = 5e-35
Identities = 302/1338 (22%), Positives = 531/1338 (39%), Gaps = 197/1338 (14%)
Query: 455 GLQHGWLTLR--GGKGF-LFTVADLQAGVVRYHHDDSDSTKDFVVFRIFDG--------- 502
G +HG L L G + +FT+ D+ R+ HD S+ T D +V +
Sbjct: 475 GARHGELELDIPGAQARKMFTLLDVVNRKARFIHDGSEDTSDQLVLEVSVTARVPMPSCL 534
Query: 503 HHSIRHKFPINVLPKDDSPPFLITN--VVIELEEGQTILIQGSMLRASDVDASDDYIFFN 560
+ PI V P +D P + + +++ LE Q L + +A D D++ + + F
Sbjct: 535 RRGQTYLLPIQVNPVNDPPHIIFPHGSLMVILEHTQKPL-GPEVFQAYDPDSACEGLTFQ 593
Query: 561 ITKPPQAGEIMKKPGPGLIGYPVHGFLQRDLFNGIIYYRHFGGEIFEDSFQFVLWDSHEP 620
+ + ++ PG P F R+L G + Y H GG + +F+ P
Sbjct: 594 VLGTSSGLPVERRDQPG---EPATEFSCRELEAGSLVYVHRGGPAQDLTFRVSDGLQASP 650
Query: 621 PNLSVPQVATIHITPVDDQLPKEAPGVSRH----LVVKETEVAYITKKQLHF-IDSESYD 675
P AT+ + + P + H L + + I L ++ D
Sbjct: 651 P-------ATLKVVAI-------RPAIQIHRSTGLRLAQGSAMPILPANLSVETNAVGQD 696
Query: 676 RELVYTITTPPFFSFSHRHLDAGKLFMVDSIPKVVKNPTALELRSFTQHAVNYMKVAYMP 735
+++ +T F + G V+ ++F Q V +V Y+
Sbjct: 697 VSVLFRVTGALQFGELQKQGAGG-----------VEGAEWWATQAFHQRDVEQGRVRYLS 745
Query: 736 PMQDIGPHCRDVQFTFSVSNQHGGT-LHGICFNITILPVDNQVPEAFTNPLKVTEGGQSI 794
D H D ++ Q G L + F +TI V PL Q
Sbjct: 746 T--DPQHHAYDTVENLALEVQVGQEILSNLSFPVTIQRAT--VWMLRLEPLHTQNTQQET 801
Query: 795 ISTEHI--LISDADTKLDNIDLSLRELPLHGRVELNGFPLNSGGTFSWGDLHTLKVRYQH 852
++T H+ + +A + + P G ++L G L+ G F+ D+ +V Y
Sbjct: 802 LTTAHLEATLEEAGPSPPTFHYEVVQAPRKGNLQLQGTRLSDGQGFTQDDIQAGRVTYGA 861
Query: 853 DG--TEVLQDDLLLEVTDGTNSAEFVLHVEVFPVN----DEPPVLKADLMPVMNCSEGGE 906
+E ++D VT + + + FP++ + PVL L+ V EGGE
Sbjct: 862 TARASEAVEDTFRFRVT----APPYFSPLYTFPIHIGGDPDAPVLTNVLLVV---PEGGE 914
Query: 907 VVITSEYIFATDVDSDNLKLMFVIAREPQHGVVRRAGVT-----VDQFSQRDVISEAVTY 961
V++++++F ++S + ++ + P+HG + G V F+ D++ + Y
Sbjct: 915 GVLSADHLFVKSLNSASY--LYEVMERPRHGRLAWRGTQDKTTMVTSFTNEDLLRGRLVY 972
Query: 962 KHTGGEIGLMPCFDTITLVVS-DGEAGPFVNGCCYNGPNPSVPLHASFPVYDLNITVYPV 1020
+H E D I V + GE+ +G + F + + PV
Sbjct: 973 QHDDSET----TEDDIPFVATRQGES---------SGDMAWEEVRGVF-----RVAIQPV 1014
Query: 1021 DNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQ-FGYLENILPS 1079
++ P I +F V G LT + ++ +D D+ D + VL FG + +
Sbjct: 1015 NDHAPVQTISRIFHVARGGRRLLTTDDVAFSDADSGFADAQLVLTRKDLLFGSIVAVDEP 1074
Query: 1080 VGFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHS---LEI- 1135
I F +D+ + +V S R + V+DG+H + LE+
Sbjct: 1075 TR--------PIYRFTQEDLRKRRVLFVHSGADR-----GWIQLQVSDGQHQATALLEVQ 1121
Query: 1136 ---PFSIIINPTNDEAPDFVVQNITVCEGQMKELDSSIISA-VDLDIPQ-DALLFSITQK 1190
P+ + N ++ + V +G +D++++ +LDI D + + +T
Sbjct: 1122 ASEPYLRVANGSS----------LVVPQGGQGTIDTAVLHLDTNLDIRSGDEVHYHVTAG 1171
Query: 1191 PRHGLLIDRGFSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFT 1250
PR G L+ G QPA +FS + L G L Y H+ S S D
Sbjct: 1172 PRWGQLVRAG---------QPAT---------AFSQQDLLDGAVL-YSHNGSLSPRDTMA 1212
Query: 1251 IQLSDGKHKILKTISVEVIPVNDEKPM-LSKKAEIAMNMGETRIISSAILSAIDEDSPRE 1309
+ G T+ V + P+ L + +I + GE I L A E P
Sbjct: 1213 FSVEAGPVHTDATLQVTIALEGPLAPLKLVRHKKIYVFQGEAAEIRRDQLEAAQEAVPPA 1272
Query: 1310 KIYYVFERLPQNGQLQL----KIGRDWVPLSPGMKCTQEEVDLNLLRYTHTGAMDSQNQD 1365
I + + P G L + + + L P +QE VD + Y H+ D
Sbjct: 1273 DIVFSVKSPPSAGYLVMVSRGALADEPPSLDPVQSFSQEAVDTGRVLYLHS--RPEAWSD 1330
Query: 1366 SFTFYLWDGNNRSPALDCQITIKDMEKGDIVILTKPLVVSKGDRGFLTTTT-LLAVDGTD 1424
+F+ + G L+ + ++ I + + V +G G LT LL V G
Sbjct: 1331 AFSLDVASG--LGAPLEGVLVELEVLPAAIPLEAQNFSVPEG--GSLTLAPPLLRVSGPY 1386
Query: 1425 KPE--ELLYVITSPPRYGQIEYVHYPGV-PITNFSQMDVVGQTVCYVHKSKVTVSSDRFR 1481
P L + PP++G ++ P ++ FS V Q + YVH T++
Sbjct: 1387 FPTLLGLSLQVLEPPQHGALQKEDGPQARTLSAFSWRMVEEQLIRYVHDGSETLTDSFVL 1446
Query: 1482 FIISNGL-RTEHGV-FEITLETVDRALPVVTRNKGLRLAQGAVGLLSPDLLQLTDPDTPA 1539
++ + R H V F +T+ V+ P++T N GL++ +GA + + L+ TD D+ +
Sbjct: 1447 MANASEMDRQSHPVAFTVTVLPVNDQPPILTTNTGLQMWEGATAPIPAEALRSTDGDSGS 1506
Query: 1540 ENLTFLLVQLPQHGQLYLWGT-GLLQHNFTQQDVDSKNVAYRHSGGDSQTDCFTFMATDG 1598
E+L + + Q P +G++ L G G +FTQ +D V + H G + F F +DG
Sbjct: 1507 EDLVYTIEQ-PSNGRVVLRGAPGTEVRSFTQAQLDGGLVLFSHRG--TLDGGFRFRLSDG 1563
Query: 1599 --TNQGFIVNGRVWEEPVLFTIQVDQLDKTAPRITLLHSPSQVGLLKNGCYGIYITSRVL 1656
T+ G ++ VL +++ Q TL P V L +S+ L
Sbjct: 1564 EHTSPGHFFRVTA-QKQVLLSLKGSQ--------TLTVCPGSVQPL---------SSQTL 1605
Query: 1657 KASDPDTEDDQ-IIFKILQGPKHG---HLENTTTGEFIHEKFSQKDLNSKTILY----II 1708
+AS D Q +++++++GP+ G H + +TGE + F+Q ++ + ILY
Sbjct: 1606 RASSSAGTDPQLLLYRVVRGPQLGRLFHAQQDSTGEAL-VNFTQAEVYAGNILYEHEMPP 1664
Query: 1709 NPSLEVNSDTVEFQIMDP 1726
P E + DT+E Q+ P
Sbjct: 1665 EPFWEAH-DTLELQLSSP 1681
Score = 134 bits (338), Expect = 7e-31
Identities = 312/1307 (23%), Positives = 488/1307 (37%), Gaps = 227/1307 (17%)
Query: 454 GGLQHGWLTLRGGKGFLFTVADLQAGVVRYHHDD--SDSTKDFVVFRIF-DGHHSIRHKF 510
G LQ L G+GF T D+QAG V Y S++ +D FR+ + S + F
Sbjct: 832 GNLQLQGTRLSDGQGF--TQDDIQAGRVTYGATARASEAVEDTFRFRVTAPPYFSPLYTF 889
Query: 511 PINVLPKDDSPPFLITNVVIELEEGQTILIQGSMLRASDVDASDDYIFFNITKPPQAGEI 570
PI++ D+P ++TNV++ + EG ++ L ++++ Y++ E+
Sbjct: 890 PIHIGGDPDAP--VLTNVLLVVPEGGEGVLSADHLFVKSLNSAS-YLY----------EV 936
Query: 571 MKKPGPGLIGYP--------VHGFLQRDLFNGIIYYRHFGGEIFEDSFQFVLWDSHEPPN 622
M++P G + + V F DL G + Y+H E ED FV E
Sbjct: 937 MERPRHGRLAWRGTQDKTTMVTSFTNEDLLRGRLVYQHDDSETTEDDIPFVATRQGESSG 996
Query: 623 ----LSVPQVATIHITPVDDQLPKEAPGVSRHLVVKETEVAYITKKQLHFIDSES--YDR 676
V V + I PV+D P + +SR V +T + F D++S D
Sbjct: 997 DMAWEEVRGVFRVAIQPVNDHAPVQT--ISRIFHVARGGRRLLTTDDVAFSDADSGFADA 1054
Query: 677 ELVYTITTPPFFSFSHRHLDAGKLFMVDSIPKVVKNPTALELRSFTQHAVNYMKVAYMPP 736
+LV T + L G + VD PT R FTQ + +V ++
Sbjct: 1055 QLVLT----------RKDLLFGSIVAVDE-------PTRPIYR-FTQEDLRKRRVLFVHS 1096
Query: 737 MQDIGPHCRDVQFTFSVSNQHGGTLHGICFNITILPVDNQVPE---AFTNPLKVTEGGQS 793
D G +Q S QH T +L V P A + L V +GGQ
Sbjct: 1097 GADRGW----IQLQVS-DGQHQAT--------ALLEVQASEPYLRVANGSSLVVPQGGQG 1143
Query: 794 IISTEHILISDADTKLD-----NIDLSLRELPLHGRVELNGFPLNSGGTFSWGDLHTLKV 848
I T + DT LD + + P G++ G P + FS DL V
Sbjct: 1144 TIDTA---VLHLDTNLDIRSGDEVHYHVTAGPRWGQLVRAGQPATA---FSQQDLLDGAV 1197
Query: 849 RYQHDGTEVLQDDLLLEVTDGTNSAEFVLHVEVFPVNDEPPVLKADLMPVMNCSEGGEVV 908
Y H+G+ +D + V G + L V + P LK + +G
Sbjct: 1198 LYSHNGSLSPRDTMAFSVEAGPVHTDATLQVTIALEGPLAP-LKLVRHKKIYVFQGEAAE 1256
Query: 909 ITSEYIFATDVDSDNLKLMFVIAREPQHG---VVRRAGVT--------VDQFSQRDVISE 957
I + + A ++F + P G +V R + V FSQ V +
Sbjct: 1257 IRRDQLEAAQEAVPPADIVFSVKSPPSAGYLVMVSRGALADEPPSLDPVQSFSQEAVDTG 1316
Query: 958 AVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVNGCCYNGPNPSVPLHASFPVYDLNITV 1017
V Y H+ E D +L V+ G P L ++
Sbjct: 1317 RVLYLHSRPEAWS----DAFSLDVASGLGAP---------------LEGVLVELEVLPAA 1357
Query: 1018 YPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPD-TAADDLEFVLVSPPQFGYLENI 1076
P++ Q F V EG S L L + P L ++ PPQ G L+
Sbjct: 1358 IPLEAQN--------FSVPEGGSLTLAPPLLRVSGPYFPTLLGLSLQVLEPPQHGALQK- 1408
Query: 1077 LPSVGFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGK--HHSLE 1134
E ++ +F W+ + I YV H E D F + + S
Sbjct: 1409 ------EDGPQARTLSAFSWRMVEEQLIRYV---HDGSETLTDSFVLMANASEMDRQSHP 1459
Query: 1135 IPFSIIINPTNDEAPDFVVQN-ITVCEGQMKELDSSIISAVDLDIPQDALLFSITQKPRH 1193
+ F++ + P ND+ P + + EG + + + + D D + L+++I Q P +
Sbjct: 1460 VAFTVTVLPVNDQPPILTTNTGLQMWEGATAPIPAEALRSTDGDSGSEDLVYTIEQ-PSN 1518
Query: 1194 GLLIDRGFSKDFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDFTIQL 1253
G ++ RG V SF+ L G+ L + H + L F +L
Sbjct: 1519 GRVVLRG---------------APGTEVRSFTQAQLDGGLVL-FSHRGT--LDGGFRFRL 1560
Query: 1254 SDGKHKILKTISVEVIPVNDEKP-MLSKKAEIAMNM--GETRIISSAILSAIDE--DSPR 1308
SDG+H T V +K +LS K + + G + +SS L A P+
Sbjct: 1561 SDGEH----TSPGHFFRVTAQKQVLLSLKGSQTLTVCPGSVQPLSSQTLRASSSAGTDPQ 1616
Query: 1309 EKIYYVFERLPQNGQL----QLKIGRDWVPLSPGMKCTQEEVDLNLLRYTHTGAMDS--Q 1362
+Y V R PQ G+L Q G V TQ EV + Y H + +
Sbjct: 1617 LLLYRVV-RGPQLGRLFHAQQDSTGEALVNF------TQAEVYAGNILYEHEMPPEPFWE 1669
Query: 1363 NQDSFTFYLWDGNNRSPALDCQITIKDMEKGDIVILTKP--------LVVSKGDRGFLTT 1414
D+ L + PA D T+ + +P L V +G R +T
Sbjct: 1670 AHDTLELQL----SSPPARDVAATLAVAVSFEAACPQRPSHLWKNKGLWVPEGQRARITV 1725
Query: 1415 TTLLA------VDGTDKPE-ELLYVITSPPRYGQIEYVHYP---GVPITNFSQMDVVGQT 1464
L A V + E ++L+ +T P GQ+ P G P +F Q +
Sbjct: 1726 AALDASNLLASVPSPQRSEHDVLFQVTQFPSRGQLLVSEEPLHAGQP--HFLQSQLAAGQ 1783
Query: 1465 VCYVHKSKVTVSSDRFRFIIS---------NGLRTEHGVFEITLETVDRALPVVTRNKGL 1515
+ Y H T D F F G +T F IT+ V+ P + L
Sbjct: 1784 LVYAHGGGGT-QQDGFHFRAHLQGPAGASVAGPQTSEA-FAITVRDVNERPPQPQASVPL 1841
Query: 1516 RLAQGAVGLLSPDLLQLTDPDTPAENLTFLLVQLPQHGQLYLWGTGLLQ-HNFTQQDVDS 1574
RL +G+ +S L + DPD+ + + + + P +G L L G GL FTQ DVDS
Sbjct: 1842 RLTRGSRAPISRAQLSVVDPDSAPGEIEYEVQRAPHNGFLSLVGGGLGPVTRFTQADVDS 1901
Query: 1575 KNVAYRHSGGDSQTDCFTFMATDGTNQGFIVNGRVWEEPVLFTIQVDQLDKTAPRITLLH 1634
+A+ + G S F +DG + ++ V P +Q+ AP L
Sbjct: 1902 GRLAFV-ANGSSVAGIFQLSMSDGASPPLPMSLAVDILPSAIEVQL-----RAP----LE 1951
Query: 1635 SPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQIIFKILQGPKHGHL 1681
P +G + + S D E+ + ++++QGP++GHL
Sbjct: 1952 VPQALGRSSLSQQQLRVVS--------DREEPEAAYRLIQGPQYGHL 1990
Score = 97.8 bits (242), Expect = 1e-19
Identities = 323/1497 (21%), Positives = 534/1497 (35%), Gaps = 226/1497 (15%)
Query: 314 SLTTSVLDC--EEDETPKPLLVFNITKAPLQGYVTHLLDHTRPISSFTWKDLSDMQIAYQ 371
+LTT+ L+ EE P + + +AP +G + FT D+ ++ Y
Sbjct: 801 TLTTAHLEATLEEAGPSPPTFHYEVVQAPRKGNLQLQGTRLSDGQGFTQDDIQAGRVTYG 860
Query: 372 PPNSSHSERRHDEVELEVY-DFFFERSAPMTVHISIRTADTNAPRVSWNTGLSLLEGQSR 430
+ SE D V +F +HI D +AP V N L + EG
Sbjct: 861 A-TARASEAVEDTFRFRVTAPPYFSPLYTFPIHIG---GDPDAP-VLTNVLLVVPEGGEG 915
Query: 431 AITWEQFQVVDNDDIGAVRLVTVGGLQHGWLTLRGGKGFL-----FTVADLQAGVVRYHH 485
++ + V + + V + +HG L RG + FT DL G + Y H
Sbjct: 916 VLSADHLFVKSLNSASYLYEV-MERPRHGRLAWRGTQDKTTMVTSFTNEDLLRGRLVYQH 974
Query: 486 DDSDSTKD---FVVFRIFDGH-----HSIRHKFPINVLPKDDSPPFLITNVVIELEEGQT 537
DDS++T+D FV R + +R F + + P +D P + + + G
Sbjct: 975 DDSETTEDDIPFVATRQGESSGDMAWEEVRGVFRVAIQPVNDHAPVQTISRIFHVARGGR 1034
Query: 538 ILIQGSMLRASDVDAS-DDYIFFNITKPPQAGEIMKKPGPGLIGYPVHGFLQRDLFNGII 596
L+ + SD D+ D K G I+ P P++ F Q DL +
Sbjct: 1035 RLLTTDDVAFSDADSGFADAQLVLTRKDLLFGSIVAVDEP---TRPIYRFTQEDLRKRRV 1091
Query: 597 YYRHFGGEIFEDSFQFVLWDSHEPPNLSVPQVATIHITPVDDQLPKEAPGVSRHLVVKET 656
+ H G + Q + D Q + + + A G S LVV +
Sbjct: 1092 LFVHSGAD--RGWIQLQVSDGQH-------QATALLEVQASEPYLRVANGSS--LVVPQG 1140
Query: 657 EVAYITKKQLHF---IDSESYDRELVYTITTPPFFSFSHRHLDAGKLFMVDSIPKVVKNP 713
I LH +D S D H H+ AG + + + +
Sbjct: 1141 GQGTIDTAVLHLDTNLDIRSGDE--------------VHYHVTAGPRW--GQLVRAGQPA 1184
Query: 714 TALELRSFTQHAVNYMKVAYMPPMQDIGPHCRDVQFTFSVSNQHGGTLHGICFNITILPV 773
TA + AV Y + P RD T + S + G +TI
Sbjct: 1185 TAFSQQDLLDGAVLYSHNGSLSP--------RD---TMAFSVEAGPVHTDATLQVTIALE 1233
Query: 774 DNQVPEAFTNPLK--VTEGGQSIISTEHILISDADTKLDNIDLSLRELPLHG------RV 825
P K V +G + I + + + +I S++ P G R
Sbjct: 1234 GPLAPLKLVRHKKIYVFQGEAAEIRRDQLEAAQEAVPPADIVFSVKSPPSAGYLVMVSRG 1293
Query: 826 ELNGFP--LNSGGTFSWGDLHTLKVRYQHDGTEVLQDDLLLEVTDGTNS--AEFVLHVEV 881
L P L+ +FS + T +V Y H E D L+V G + ++ +EV
Sbjct: 1294 ALADEPPSLDPVQSFSQEAVDTGRVLYLHSRPEAWSDAFSLDVASGLGAPLEGVLVELEV 1353
Query: 882 FPVNDEPPVLKADLMPVMNCS--EGGEVVITSEYIFATDVDSDN-LKLMFVIAREPQHGV 938
P A + N S EGG + + + + L L + PQHG
Sbjct: 1354 LPA--------AIPLEAQNFSVPEGGSLTLAPPLLRVSGPYFPTLLGLSLQVLEPPQHGA 1405
Query: 939 VRR----AGVTVDQFSQRDVISEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVNGCC 994
+++ T+ FS R V + + Y H G E D+ L+ + E
Sbjct: 1406 LQKEDGPQARTLSAFSWRMVEEQLIRYVHDGSE----TLTDSFVLMANASEMD------- 1454
Query: 995 YNGPNPSVPLHASFPVYDLNITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPD 1054
S PV +TV PV++QPP + + EG + + L +TD D
Sbjct: 1455 ----------RQSHPV-AFTVTVLPVNDQPPILTTNTGLQMWEGATAPIPAEALRSTDGD 1503
Query: 1055 TAADDLEFVLVSPPQFGYLENILPSVGFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRI 1114
+ ++DL + + P + P G + SF ++ + + L
Sbjct: 1504 SGSEDLVYTIEQPSNGRVVLRGAP---------GTEVRSFTQAQLDGGLVLFSHRGTL-- 1552
Query: 1115 EPTADQFTVYVTDGKHHS------LEIPFSIIINPTNDEAPDFVVQNITVCEGQMKELDS 1168
F ++DG+H S + ++++ Q +TVC G ++ L S
Sbjct: 1553 ---DGGFRFRLSDGEHTSPGHFFRVTAQKQVLLSLKGS-------QTLTVCPGSVQPLSS 1602
Query: 1169 SIISA-VDLDIPQDALLFSITQKPRHGLLIDRGFSKDFSENKQPANPHQKHAPVHSFSME 1227
+ A LL+ + + P+ G L ++ S + N Q + E
Sbjct: 1603 QTLRASSSAGTDPQLLLYRVVRGPQLGRLF---HAQQDSTGEALVNFTQAEVYAGNILYE 1659
Query: 1228 LLKTGMRLTYMHDDSESLADDFTIQLSDGKHK-ILKTISVEVI--PVNDEKPM-LSKKAE 1283
HD E +QLS + + T++V V ++P L K
Sbjct: 1660 HEMPPEPFWEAHDTLE-------LQLSSPPARDVAATLAVAVSFEAACPQRPSHLWKNKG 1712
Query: 1284 IAMNMGETRIISSAILSA----IDEDSPREK---IYYVFERLPQNGQLQLKIGRDWVPLS 1336
+ + G+ I+ A L A SP+ + + + P GQL + PL
Sbjct: 1713 LWVPEGQRARITVAALDASNLLASVPSPQRSEHDVLFQVTQFPSRGQLLV----SEEPLH 1768
Query: 1337 PGM-KCTQEEVDLNLLRYTHTGAMDSQNQDSFTFYLWD-------GNNRSPALDCQITIK 1388
G Q ++ L Y H G Q+ F +L G S A IT++
Sbjct: 1769 AGQPHFLQSQLAAGQLVYAHGGGGTQQDGFHFRAHLQGPAGASVAGPQTSEAF--AITVR 1826
Query: 1389 DM-EKGDIVILTKPLVVSKGDRGFLTTTTLLAVDGTDKPEELLYVITSPPRYGQIEYVHY 1447
D+ E+ + PL +++G R ++ L VD P E+ Y + P G + V
Sbjct: 1827 DVNERPPQPQASVPLRLTRGSRAPISRAQLSVVDPDSAPGEIEYEVQRAPHNGFLSLVGG 1886
Query: 1448 PGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFIISNGLRTEHGVFEITLETVDRALP 1507
P+T F+Q DV + +V F+ +S+G + + ++ + A+
Sbjct: 1887 GLGPVTRFTQADVDSGRLAFVANGSSVAGI--FQLSMSDGASPPLPM-SLAVDILPSAIE 1943
Query: 1508 VVTRNK-GLRLAQGAVGLLSPDLLQLTDPDTPAENLTFLLVQLPQHGQLYLWGTGLLQHN 1566
V R + A G L L ++D + P + L+Q PQ+G L + G
Sbjct: 1944 VQLRAPLEVPQALGRSSLSQQQLRVVSDREEP--EAAYRLIQGPQYGHLLVGGRP--TSA 1999
Query: 1567 FTQQDVDSKNVAYRHSGGDSQTDCFTFMA-TDGTNQGFIVNGRVWEEPVLFTIQVDQLDK 1625
F+Q +D V + + S D F +A G N +VN V
Sbjct: 2000 FSQFQIDQGEVVFAFTNFSSSHDHFRVLALARGVNASAVVNVTV---------------- 2043
Query: 1626 TAPRITLLHSPSQVGLLKNGCYGIYITSRVLKASDPDTEDDQI-IFKILQGPKHGHL--- 1681
LLH + G G + + VL A + + F++L+GP+HG +
Sbjct: 2044 ----RALLHVWAG-GPWPQGA-TLRLDPTVLDAGELANRTGSVPRFRLLEGPRHGRVVRV 2097
Query: 1682 ---ENTTTGEFIHEKFSQKDLNSKTILYIINPSLEVNSDTVEFQIMDPTGNSATPQI 1735
G + E+F+Q+DL + LEV E + P G+S T ++
Sbjct: 2098 PRARTEPGGSQLVEQFTQQDLEDGRL------GLEVGRP--EGRAPGPAGDSLTLEL 2146
Score = 89.0 bits (219), Expect = 5e-17
Identities = 194/867 (22%), Positives = 333/867 (38%), Gaps = 111/867 (12%)
Query: 902 SEGGEVVITSEYIFAT----DVDSDNLKLMFVIAREPQHGVVRR---AGVTVDQFSQRDV 954
+EGG + ++ T + + +++F + R +HG + F+ DV
Sbjct: 440 AEGGTAWLEWRHVQPTLDLMEAELRKSQVLFSVTRGARHGELELDIPGAQARKMFTLLDV 499
Query: 955 ISEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVNGCCYNGPNPSVPLHASFPVYDLN 1014
++ + H G E D + L VS P + C G Y L
Sbjct: 500 VNRKARFIHDGSE----DTSDQLVLEVSVTARVPMPS-CLRRGQT-----------YLLP 543
Query: 1015 ITVYPVDNQPPSIAI--GPVFVVDEGCSTALTVNHLSATDPDTAADDLEFVLVSPPQFGY 1072
I V PV N PP I G + V+ E L A DPD+A + L F ++
Sbjct: 544 IQVNPV-NDPPHIIFPHGSLMVILEHTQKPLGPEVFQAYDPDSACEGLTFQVLGTSSGLP 602
Query: 1073 LENILPSVGFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTVYVTDGKHHS 1132
+E + G F +++ A + YV R P D T V+DG S
Sbjct: 603 VER--------RDQPGEPATEFSCRELEAGSLVYVH----RGGPAQD-LTFRVSDGLQAS 649
Query: 1133 LEIPFSII-INPTNDEAPDFVVQNITVCEGQMKELDSSIISAVDLDIPQD-ALLFSITQK 1190
++ I P + + +G + + +S + QD ++LF +T
Sbjct: 650 PPATLKVVAIRPAIQIHRS---TGLRLAQGSAMPILPANLSVETNAVGQDVSVLFRVTGA 706
Query: 1191 PRHGLLIDRGFSK-DFSENKQPANPHQKHAPVHSFSMELLKTGMRLTYMHDDSESLADDF 1249
+ G L +G + +E HQ+ V + L T + + +D E+LA
Sbjct: 707 LQFGELQKQGAGGVEGAEWWATQAFHQRD--VEQGRVRYLSTDPQ-HHAYDTVENLA--- 760
Query: 1250 TIQLSDGKHKILKTISVEVIPVNDEKPMLSKKAEIAMNMGETRIISSAILSAIDEDSPRE 1309
+++ G+ +IL +S V ML + N + + ++ + + ++E P
Sbjct: 761 -LEVQVGQ-EILSNLSFPVTIQRATVWMLRLEPLHTQNTQQETLTTAHLEATLEEAGPSP 818
Query: 1310 KIY-YVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNLLRYTHTGAMDSQNQDSFT 1368
+ Y + P+ G LQL+ R LS G TQ+++ + Y T +D+F
Sbjct: 819 PTFHYEVVQAPRKGNLQLQGTR----LSDGQGFTQDDIQAGRVTYGATARASEAVEDTFR 874
Query: 1369 FYLWDGNNRSPALDCQITIKDMEKGDIVILTKPL-VVSKGDRGFLTTTTLLAVDGTDKPE 1427
F + SP I I D +LT L VV +G G L+ L
Sbjct: 875 FRVTAPPYFSPLYTFPIHIGG--DPDAPVLTNVLLVVPEGGEGVLSADHLFVKSLNSA-- 930
Query: 1428 ELLYVITSPPRYGQIEY--VHYPGVPITNFSQMDVVGQTVCYVHKSKVTVSSDRFRFIIS 1485
LY + PR+G++ + +T+F+ D++ + Y H T D F+ +
Sbjct: 931 SYLYEVMERPRHGRLAWRGTQDKTTMVTSFTNEDLLRGRLVYQHDDSETTEDD-IPFVAT 989
Query: 1486 NGLRTE--------HGVFEITLETVDRALPVVTRNKGLRLAQGAVGLLSPDLLQLTDPDT 1537
+ GVF + ++ V+ PV T ++ +A+G LL+ D + +D D+
Sbjct: 990 RQGESSGDMAWEEVRGVFRVAIQPVNDHAPVQTISRIFHVARGGRRLLTTDDVAFSDADS 1049
Query: 1538 PAENLTFLLVQLPQHGQLYLWGTGLLQ-------HNFTQQDVDSKNVAYRHSGGDSQTDC 1590
F QL + L+G+ + + FTQ+D+ + V + HSG D
Sbjct: 1050 -----GFADAQLVLTRKDLLFGSIVAVDEPTRPIYRFTQEDLRKRRVLFVHSGAD--RGW 1102
Query: 1591 FTFMATDGTNQGFIVNGRVWEEPVLFTIQVDQLDKTAPRITLLHSPSQVGLLKNGCYGIY 1650
+DG +Q L +Q + P + + + S V + G G
Sbjct: 1103 IQLQVSDGQHQA----------TALLEVQASE-----PYLRVANGSSLV--VPQGGQGTI 1145
Query: 1651 ITSRVLKASDPDTED-DQIIFKILQGPKHGHLENTTTGEFIHEKFSQKDLNSKTILYIIN 1709
T+ + ++ D D++ + + GP+ G L FSQ+DL +LY N
Sbjct: 1146 DTAVLHLDTNLDIRSGDEVHYHVTAGPRWGQLVRAGQPA---TAFSQQDLLDGAVLYSHN 1202
Query: 1710 PSLEVNSDTVEFQI-MDPTGNSATPQI 1735
SL DT+ F + P AT Q+
Sbjct: 1203 GSLSPR-DTMAFSVEAGPVHTDATLQV 1228
Score = 79.7 bits (195), Expect = 3e-14
Identities = 213/1014 (21%), Positives = 384/1014 (37%), Gaps = 153/1014 (15%)
Query: 783 NPLKVTEGGQSIISTEHIL----ISDADTKLDNIDLSLRELPLHGRVELNGFPLNSGGTF 838
+PL V EGG + + H+ + +A+ + + S+ HG +EL+ + F
Sbjct: 435 SPLVVAEGGTAWLEWRHVQPTLDLMEAELRKSQVLFSVTRGARHGELELDIPGAQARKMF 494
Query: 839 SWGDLHTLKVRYQHDGTEVLQDDLLLEVTDGT---------NSAEFVLHVEVFPVNDEPP 889
+ D+ K R+ HDG+E D L+LEV+ ++L ++V PVND P
Sbjct: 495 TLLDVVNRKARFIHDGSEDTSDQLVLEVSVTARVPMPSCLRRGQTYLLPIQVNPVNDPPH 554
Query: 890 VL--KADLMPVMNCSEGGEVVITSEYIFATDVDSDNLKLMF-VIAREPQHGVVRR--AGV 944
++ LM ++ E + + E A D DS L F V+ V RR G
Sbjct: 555 IIFPHGSLMVIL---EHTQKPLGPEVFQAYDPDSACEGLTFQVLGTSSGLPVERRDQPGE 611
Query: 945 TVDQFSQRDVISEAVTYKHTGGEIGLMPCFDTITLVVSDGEAGPFVNGCCYNGPNPSVPL 1004
+FS R++ + ++ Y H GG P D +T VSDG L
Sbjct: 612 PATEFSCRELEAGSLVYVHRGG-----PAQD-LTFRVSDG-------------------L 646
Query: 1005 HASFPVYDLNITVYPVDNQPPSIAIGPVFVVDEGCSTALTVNHLSATDPDTAAD-DLEFV 1063
AS P + + P S + + +G + + +LS D + F
Sbjct: 647 QASPPATLKVVAIRPAIQIHRSTGLR----LAQGSAMPILPANLSVETNAVGQDVSVLFR 702
Query: 1064 LVSPPQFGYLENILPSVGFEKSNIGISIDSFQWKDMNAFHINYVQSRHLRIEPTADQFTV 1123
+ QFG L +K G ++ +W AFH V+ +R T Q
Sbjct: 703 VTGALQFGEL---------QKQGAG-GVEGAEWWATQAFHQRDVEQGRVRYLSTDPQHHA 752
Query: 1124 YVT-DGKHHSLEIPFSIIIN---PTNDEAPDFVVQNITVCEGQMKELDSSIISAVDLDIP 1179
Y T + +++ I+ N P + + + Q + ++ + ++ +
Sbjct: 753 YDTVENLALEVQVGQEILSNLSFPVTIQRATVWMLRLEPLHTQNTQQETLTTAHLEATLE 812
Query: 1180 Q-----DALLFSITQKPRHGLLIDRGFSKDFSENKQPANPHQKHAPVHSFSMELLKTGMR 1234
+ + + Q PR G L +G + + F+ + ++ G R
Sbjct: 813 EAGPSPPTFHYEVVQAPRKGNLQLQG---------------TRLSDGQGFTQDDIQAG-R 856
Query: 1235 LTY--MHDDSESLADDFTIQLSDGKH-KILKTISVEVIPVNDEKPMLSKKAEIAMNMGET 1291
+TY SE++ D F +++ + L T + I + + P+L+ + GE
Sbjct: 857 VTYGATARASEAVEDTFRFRVTAPPYFSPLYTFPIH-IGGDPDAPVLTNVLLVVPEGGEG 915
Query: 1292 RIISSAILSAIDEDSPREKIYYVFERLPQNGQLQLKIGRDWVPLSPGMKCTQEEVDLNLL 1351
+ SA + + +Y V ER P++G+L + +D + T E++ L
Sbjct: 916 --VLSADHLFVKSLNSASYLYEVMER-PRHGRLAWRGTQDKTTMVTSF--TNEDLLRGRL 970
Query: 1352 RYTHTGAMDSQNQDSFTFYLWDGNNRSPALD-----CQITIKDM-EKGDIVILTKPLVVS 1405
Y H + +++ F ++ A + ++ I+ + + + +++ V+
Sbjct: 971 VYQHDDSETTEDDIPFVATRQGESSGDMAWEEVRGVFRVAIQPVNDHAPVQTISRIFHVA 1030
Query: 1406 KGDRGFLTTTTLLAVDGTDKPEELLYVITSPP-RYGQIEYVHYPGVPITNFSQMDVVGQT 1464
+G R LTT + D + V+T +G I V P PI F+Q D+ +
Sbjct: 1031 RGGRRLLTTDDVAFSDADSGFADAQLVLTRKDLLFGSIVAVDEPTRPIYRFTQEDLRKRR 1090
Query: 1465 VCYVHKSKVTVSSDR--FRFIISNGLRTEHGVFEITLETVDRALPVVTRNKGLRLAQGAV 1522
V +VH +DR + +S+G + E+ V L + QG
Sbjct: 1091 VLFVHS-----GADRGWIQLQVSDGQHQATALLEV---QASEPYLRVANGSSLVVPQGGQ 1142
Query: 1523 GLLSPDLLQL-TDPD-TPAENLTFLLVQLPQHGQLYLWGTGLLQHNFTQQDVDSKNVAYR 1580
G + +L L T+ D + + + + P+ GQL G F+QQD+ V Y
Sbjct: 1143 GTIDTAVLHLDTNLDIRSGDEVHYHVTAGPRWGQLVRAGQPATA--FSQQDLLDGAVLYS 1200
Query: 1581 HSGGDSQTDCFTFMATDGTNQGFIVNGRVWEEPVLFTIQVDQLDKTAPRITLLHSP-SQV 1639
H+G S D F G PV D T L P + +
Sbjct: 1201 HNGSLSPRDTMAFSVEAG--------------PV-------HTDATLQVTIALEGPLAPL 1239
Query: 1640 GLLKNGCYGIY------ITSRVLKASDPDTEDDQIIFKILQGPKHGHLENTTTGEFIHE- 1692
L+++ ++ I L+A+ I+F + P G+L + G E
Sbjct: 1240 KLVRHKKIYVFQGEAAEIRRDQLEAAQEAVPPADIVFSVKSPPSAGYLVMVSRGALADEP 1299
Query: 1693 -------KFSQKDLNSKTILYIINPSLEVNSDTVEFQIMDPTGNSATPQILELK 1739
FSQ+ +++ +LY ++ E SD + G ++EL+
Sbjct: 1300 PSLDPVQSFSQEAVDTGRVLY-LHSRPEAWSDAFSLDVASGLGAPLEGVLVELE 1352
>gi|4505245 mannose receptor C type 1 precursor [Homo sapiens]
Length = 1456
Score = 65.1 bits (157), Expect = 7e-10
Identities = 41/141 (29%), Positives = 70/141 (49%), Gaps = 9/141 (6%)
Query: 2043 PQTKDVEDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWL 2102
P DV CP+ W ++G+C+ + ++K A CR++ G+L ++ + + + ++
Sbjct: 353 PSESDVPTH-CPSQWWPYAGHCYKIHRDEKKIQRDALTTCRKEG-GDLTSIHTIEELDFI 410
Query: 2103 WDIGGRK---SFWIGLNDQVHAGHWEWIGGEPVAFTNGRRG-PSQRSKLGKSCVLVQ-RQ 2157
G + WIGLND ++EW G PV FT RG PS + + CV+++ +
Sbjct: 411 ISQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKD 470
Query: 2158 GKWQTKDCRRAKPHNYVCSRK 2178
G W + C P Y+C K
Sbjct: 471 GYWADRGCE--WPLGYICKMK 489
Score = 47.8 bits (112), Expect = 1e-04
Identities = 32/101 (31%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
Query: 2039 KAWSPQTKDVEDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQH 2098
++ P+ +VE K C GW +H YC+ +I T+ A Q C + L T+ R
Sbjct: 491 RSQGPEIVEVE-KGCRKGWKKHHFYCY-MIGHTLSTFAEANQTCNNEN-AYLTTIEDRYE 547
Query: 2099 MRWLWDIGG---RKSFWIGLNDQVHAGHWEWIGGEPVAFTN 2136
+L G K FW GL+D G ++W E V FT+
Sbjct: 548 QAFLTSFVGLRPEKYFWTGLSDIQTKGTFQWTIEEEVRFTH 588
Score = 47.0 bits (110), Expect = 2e-04
Identities = 38/141 (26%), Positives = 61/141 (43%), Gaps = 18/141 (12%)
Query: 2053 CPAGWHQHSGYCHIL---ITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGRK 2109
C GW+ +S C + + E++ W A +AC + GNLV++ + + +L
Sbjct: 945 CKEGWNFYSNKCFKIFGFMEEERKNWQEARKACIG-FGGNLVSIQNEKEQAFLTYHMKDS 1003
Query: 2110 SF--WIGLNDQVHAGHWEWIGGEPVAFTNGRRG--PSQRSKLG---KSCVLV-----QRQ 2157
+F W GLND + W G V +TN +G +RS L CV++
Sbjct: 1004 TFSAWTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGGASNEA 1063
Query: 2158 GKWQTKDCRRAKPHNYVCSRK 2178
GKW C + Y+C +
Sbjct: 1064 GKWMDDTCDSKR--GYICQTR 1082
Score = 47.0 bits (110), Expect = 2e-04
Identities = 37/134 (27%), Positives = 52/134 (38%), Gaps = 15/134 (11%)
Query: 2053 CP----AGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLW----D 2104
CP W G+C+ + + W A+ C +LV++ S +L
Sbjct: 1230 CPESDHTAWIPFHGHCYYIESSYTRNWGQASLECLRMG-SSLVSIESAAESSFLSYRVEP 1288
Query: 2105 IGGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCV-LVQRQGKWQTK 2163
+ + +FWIGL V G W WI PV+F N G + CV L G W
Sbjct: 1289 LKSKTNFWIGLFRNVE-GTWLWINNSPVSFVNWNTGDPSGER--NDCVALHASSGFWSNI 1345
Query: 2164 DCRRAKPHNYVCSR 2177
C K Y+C R
Sbjct: 1346 HCSSYK--GYICKR 1357
Score = 45.8 bits (107), Expect = 5e-04
Identities = 28/108 (25%), Positives = 49/108 (45%), Gaps = 8/108 (7%)
Query: 2074 TWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGR--KSFWIGLNDQVHAGHWEWIGGEP 2131
TW+ A ++C++Q L+++ +L + WIGLN W+W P
Sbjct: 239 TWHQARKSCQQQN-AELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWSDRSP 297
Query: 2132 VAFTNGRRGPSQRSKLGKSCVLVQ--RQGKWQTKDCRRAKPHNYVCSR 2177
+ N G S ++ GKSCV + + KW+ +C + Y+C +
Sbjct: 298 FRYLNWLPG-SPSAEPGKSCVSLNPGKNAKWENLEC--VQKLGYICKK 342
Score = 40.0 bits (92), Expect = 0.025
Identities = 30/143 (20%), Positives = 56/143 (39%), Gaps = 11/143 (7%)
Query: 2043 PQTKDVEDKSCPAGWHQHS--GYCHILITE---QKGTWNAAAQACREQYLGNLVTVFSRQ 2097
P+ + CP W S C L + +K TW + CR G+L ++ +++
Sbjct: 636 PKPTTTPEPKCPEDWGASSRTSLCFKLYAKGKHEKKTWFESRDFCRALG-GDLASINNKE 694
Query: 2098 HMRWLWDI-----GGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCV 2152
+ +W + K FW+GL + + W G PV++ N G + + C
Sbjct: 695 EQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCG 754
Query: 2153 LVQRQGKWQTKDCRRAKPHNYVC 2175
++ D +N++C
Sbjct: 755 ELKGDPTMSWNDINCEHLNNWIC 777
Score = 39.3 bits (90), Expect = 0.043
Identities = 26/112 (23%), Positives = 45/112 (40%), Gaps = 8/112 (7%)
Query: 2068 ITEQKGTWNAAAQACR--EQYLGNLVTVFSRQHMRWLWDIGGRKSFWIGLNDQVHAGHWE 2125
+ QK W+ A C+ + +++ +S WL + WI LN + +
Sbjct: 1109 LMRQKFQWHEAETYCKLHNSLIASILDPYSNA-FAWLQMETSNERVWIALNSNLTDNQYT 1167
Query: 2126 WIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKWQTKDCRRAKPHNYVCSR 2177
W V +TN + KL +CV + G W+T C + ++C R
Sbjct: 1168 WTDKWRVRYTNWA---ADEPKLKSACVYLDLDGYWKTAHCNES--FYFLCKR 1214
Score = 38.9 bits (89), Expect = 0.056
Identities = 29/127 (22%), Positives = 58/127 (45%), Gaps = 10/127 (7%)
Query: 2056 GWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGR----KSF 2111
GW + Y + +++K T + A C+ + G+LV++ S ++LW R ++
Sbjct: 803 GWVIYKDYQYYF-SKEKETMDNARAFCKRNF-GDLVSIQSESEKKFLWKYVNRNDAQSAY 860
Query: 2112 WIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCV-LVQRQGKWQTKDCRRAKP 2170
+IGL + + W+ G V + + G + ++CV + G W +C P
Sbjct: 861 FIGLLISLDK-KFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGFWNDINC--GYP 917
Query: 2171 HNYVCSR 2177
+ ++C R
Sbjct: 918 NAFICQR 924
>gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]
Length = 2317
Score = 64.3 bits (155), Expect = 1e-09
Identities = 41/145 (28%), Positives = 70/145 (48%), Gaps = 13/145 (8%)
Query: 2038 WKAWSPQTKDVEDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQ--YLGNLVTVFS 2095
WK S T + + C GW+++ G+C+ +++ TW A + CREQ +L ++VT
Sbjct: 2154 WKRESESTA-ADQEVCEEGWNKYQGHCYRHFPDRE-TWVDAERRCREQQSHLSSIVTPEE 2211
Query: 2096 RQHMRWLWDIGGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGR-RGPSQRSKLGKSCVLV 2154
++ + + + WIGLND+ G + W G P+ F N R P G+ CV++
Sbjct: 2212 QEFV----NNNAQDYQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVM 2267
Query: 2155 --QRQGKWQTKDCRRAKPHNYVCSR 2177
+G+W C P + C +
Sbjct: 2268 IWHEKGEWNDVPCNYHLP--FTCKK 2290
>gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]
Length = 2416
Score = 63.2 bits (152), Expect = 3e-09
Identities = 37/136 (27%), Positives = 68/136 (50%), Gaps = 12/136 (8%)
Query: 2047 DVEDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQ--YLGNLVTVFSRQHMRWLWD 2104
+++ + C GW+++ G+C+ +++ TW A + CREQ +L ++VT ++ + +
Sbjct: 2200 NIDQEVCEEGWNKYQGHCYRHFPDRE-TWVDAERRCREQQSHLSSIVTPEEQEFV----N 2254
Query: 2105 IGGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGR-RGPSQRSKLGKSCVLV--QRQGKWQ 2161
+ WIGLND+ G + W G P+ F N R P G+ CV++ +G+W
Sbjct: 2255 NNAQDYQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWN 2314
Query: 2162 TKDCRRAKPHNYVCSR 2177
C P + C +
Sbjct: 2315 DVPCNYHLP--FTCKK 2328
>gi|57546917 mannose receptor, C type 1-like 1 [Homo sapiens]
Length = 1456
Score = 62.0 bits (149), Expect = 6e-09
Identities = 40/141 (28%), Positives = 68/141 (48%), Gaps = 9/141 (6%)
Query: 2043 PQTKDVEDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWL 2102
P DV CP+ W ++G+C+ + ++K A CR++ +L ++ + + ++
Sbjct: 353 PSESDVPTH-CPSQWWPYAGHCYKIHRDEKKIQRDALTTCRKEG-SDLASIHTIEEFDFI 410
Query: 2103 WDIGGRK---SFWIGLNDQVHAGHWEWIGGEPVAFTNGRRG-PSQRSKLGKSCVLVQ-RQ 2157
G + WIGLND ++EW G PV FT RG PS + + CV+++ +
Sbjct: 411 ISQLGYEPNDELWIGLNDIKIQMYFEWSDGTPVTFTKWLRGEPSHENNRQEDCVVMKGKD 470
Query: 2158 GKWQTKDCRRAKPHNYVCSRK 2178
G W + C P Y+C K
Sbjct: 471 GYWADRGCE--WPLGYICKMK 489
Score = 47.8 bits (112), Expect = 1e-04
Identities = 32/101 (31%), Positives = 47/101 (46%), Gaps = 6/101 (5%)
Query: 2039 KAWSPQTKDVEDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQH 2098
++ P+ +VE K C GW +H YC+ +I T+ A Q C + L T+ R
Sbjct: 491 RSQGPEIVEVE-KGCRKGWKKHHFYCY-MIGHTLSTFAEANQTCNNEN-AYLTTIEDRYE 547
Query: 2099 MRWLWDIGG---RKSFWIGLNDQVHAGHWEWIGGEPVAFTN 2136
+L G K FW GL+D G ++W E V FT+
Sbjct: 548 QAFLTSFVGLRPEKYFWTGLSDIQTKGTFQWTIEEEVRFTH 588
Score = 47.0 bits (110), Expect = 2e-04
Identities = 38/141 (26%), Positives = 61/141 (43%), Gaps = 18/141 (12%)
Query: 2053 CPAGWHQHSGYCHIL---ITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGRK 2109
C GW+ +S C + + E++ W A +AC + GNLV++ + + +L
Sbjct: 945 CKEGWNFYSNKCFKIFGFMEEERKNWQEARKACIG-FGGNLVSIQNEKEQAFLTYHMKDS 1003
Query: 2110 SF--WIGLNDQVHAGHWEWIGGEPVAFTNGRRG--PSQRSKLG---KSCVLV-----QRQ 2157
+F W GLND + W G V +TN +G +RS L CV++
Sbjct: 1004 TFSAWTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPGGRRSSLSYEDADCVVIIGGASNEA 1063
Query: 2158 GKWQTKDCRRAKPHNYVCSRK 2178
GKW C + Y+C +
Sbjct: 1064 GKWMDDTCDSKR--GYICQTR 1082
Score = 47.0 bits (110), Expect = 2e-04
Identities = 37/134 (27%), Positives = 52/134 (38%), Gaps = 15/134 (11%)
Query: 2053 CP----AGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLW----D 2104
CP W G+C+ + + W A+ C +LV++ S +L
Sbjct: 1230 CPESDHTAWIPFHGHCYYIESSYTRNWGQASLECLRMG-SSLVSIESAAESSFLSYRVEP 1288
Query: 2105 IGGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCV-LVQRQGKWQTK 2163
+ + +FWIGL V G W WI PV+F N G + CV L G W
Sbjct: 1289 LKSKTNFWIGLFRNVE-GTWLWINNSPVSFVNWNTGDPSGER--NDCVALHASSGFWSNI 1345
Query: 2164 DCRRAKPHNYVCSR 2177
C K Y+C R
Sbjct: 1346 HCSSYK--GYICKR 1357
Score = 45.8 bits (107), Expect = 5e-04
Identities = 28/108 (25%), Positives = 49/108 (45%), Gaps = 8/108 (7%)
Query: 2074 TWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGR--KSFWIGLNDQVHAGHWEWIGGEP 2131
TW+ A ++C++Q L+++ +L + WIGLN W+W P
Sbjct: 239 TWHQARKSCQQQN-AELLSITEIHEQTYLTGLTSSLTSGLWIGLNSLSFNSGWQWSDRSP 297
Query: 2132 VAFTNGRRGPSQRSKLGKSCVLVQ--RQGKWQTKDCRRAKPHNYVCSR 2177
+ N G S ++ GKSCV + + KW+ +C + Y+C +
Sbjct: 298 FRYLNWLPG-SPSAEPGKSCVSLNPGKNAKWENLEC--VQKLGYICKK 342
Score = 40.0 bits (92), Expect = 0.025
Identities = 30/143 (20%), Positives = 56/143 (39%), Gaps = 11/143 (7%)
Query: 2043 PQTKDVEDKSCPAGWHQHS--GYCHILITE---QKGTWNAAAQACREQYLGNLVTVFSRQ 2097
P+ + CP W S C L + +K TW + CR G+L ++ +++
Sbjct: 636 PKPTTTPEPKCPEDWGASSRTSLCFKLYAKGKHEKKTWFESRDFCRALG-GDLASINNKE 694
Query: 2098 HMRWLWDI-----GGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCV 2152
+ +W + K FW+GL + + W G PV++ N G + + C
Sbjct: 695 EQQTIWRLITASGSYHKLFWLGLTYGSPSEGFTWSDGSPVSYENWAYGEPNNYQNVEYCG 754
Query: 2153 LVQRQGKWQTKDCRRAKPHNYVC 2175
++ D +N++C
Sbjct: 755 ELKGDPTMSWNDINCEHLNNWIC 777
Score = 39.3 bits (90), Expect = 0.043
Identities = 26/112 (23%), Positives = 45/112 (40%), Gaps = 8/112 (7%)
Query: 2068 ITEQKGTWNAAAQACR--EQYLGNLVTVFSRQHMRWLWDIGGRKSFWIGLNDQVHAGHWE 2125
+ QK W+ A C+ + +++ +S WL + WI LN + +
Sbjct: 1109 LMRQKFQWHEAETYCKLHNSLIASILDPYSNA-FAWLQMETSNERVWIALNSNLTDNQYT 1167
Query: 2126 WIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKWQTKDCRRAKPHNYVCSR 2177
W V +TN + KL +CV + G W+T C + ++C R
Sbjct: 1168 WTDKWRVRYTNWA---ADEPKLKSACVYLDLDGYWKTAHCNES--FYFLCKR 1214
Score = 38.9 bits (89), Expect = 0.056
Identities = 29/127 (22%), Positives = 58/127 (45%), Gaps = 10/127 (7%)
Query: 2056 GWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGR----KSF 2111
GW + Y + +++K T + A C+ + G+LV++ S ++LW R ++
Sbjct: 803 GWVIYKDYQYYF-SKEKETMDNARAFCKRNF-GDLVSIQSESEKKFLWKYVNRNDAQSAY 860
Query: 2112 WIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCV-LVQRQGKWQTKDCRRAKP 2170
+IGL + + W+ G V + + G + ++CV + G W +C P
Sbjct: 861 FIGLLISLDK-KFAWMDGSKVDYVSWATGEPNFANEDENCVTMYSNSGFWNDINC--GYP 917
Query: 2171 HNYVCSR 2177
+ ++C R
Sbjct: 918 NAFICQR 924
>gi|118600983 chondroitin sulfate proteoglycan 3 [Homo sapiens]
Length = 1321
Score = 61.2 bits (147), Expect = 1e-08
Identities = 39/135 (28%), Positives = 63/135 (46%), Gaps = 10/135 (7%)
Query: 2046 KDVEDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDI 2105
KD E C GWH+ G+C+ ++ W A + CR + G+L +V S + ++
Sbjct: 1083 KDTE--GCDRGWHKFQGHCYRYFAHRRA-WEDAEKDCRRRS-GHLTSVHSPEEHSFINSF 1138
Query: 2106 GGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRG-PSQRSKLGKSCVLV--QRQGKWQT 2162
G ++ WIGLND++ ++W + F N R P G+ CV++ G+W
Sbjct: 1139 G-HENTWIGLNDRIVERDFQWTDNTGLQFENWRENQPDNFFAGGEDCVVMVAHESGRWND 1197
Query: 2163 KDCRRAKPHNYVCSR 2177
C P YVC +
Sbjct: 1198 VPCNYNLP--YVCKK 1210
>gi|187607300 versican isoform 2 [Homo sapiens]
Length = 655
Score = 60.1 bits (144), Expect = 2e-08
Identities = 33/120 (27%), Positives = 58/120 (48%), Gaps = 6/120 (5%)
Query: 2049 EDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGR 2108
+ ++C GWH+ G C+ ++ TW+AA + CR Q +L ++ S + ++ +G
Sbjct: 424 DTETCDYGWHKFQGQCYKYFAHRR-TWDAAERECRLQG-AHLTSILSHEEQMFVNRVGHD 481
Query: 2109 KSFWIGLNDQVHAGHWEWIGGEPVAFTNGR-RGPSQRSKLGKSCVLV--QRQGKWQTKDC 2165
WIGLND++ + W G + + N R P G+ CV++ G+W C
Sbjct: 482 YQ-WIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPC 540
>gi|21361116 versican isoform 1 [Homo sapiens]
Length = 3396
Score = 60.1 bits (144), Expect = 2e-08
Identities = 33/120 (27%), Positives = 58/120 (48%), Gaps = 6/120 (5%)
Query: 2049 EDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGR 2108
+ ++C GWH+ G C+ ++ TW+AA + CR Q +L ++ S + ++ +G
Sbjct: 3165 DTETCDYGWHKFQGQCYKYFAHRR-TWDAAERECRLQG-AHLTSILSHEEQMFVNRVGHD 3222
Query: 2109 KSFWIGLNDQVHAGHWEWIGGEPVAFTNGR-RGPSQRSKLGKSCVLV--QRQGKWQTKDC 2165
WIGLND++ + W G + + N R P G+ CV++ G+W C
Sbjct: 3223 YQ-WIGLNDKMFEHDFRWTDGSTLQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPC 3281
>gi|144446030 lymphocyte antigen 75 [Homo sapiens]
Length = 1722
Score = 58.5 bits (140), Expect = 7e-08
Identities = 41/135 (30%), Positives = 63/135 (46%), Gaps = 8/135 (5%)
Query: 2050 DKSCPAGWHQHS--GYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGG 2107
+ C W ++ G C+ T+ +W A +C+ Q +L+++ S + +L + G
Sbjct: 213 ENGCEDNWEKNEQFGSCYQFNTQTALSWKEAYVSCQNQG-ADLLSINSAAELTYLKEKEG 271
Query: 2108 -RKSFWIGLNDQVHAGHWEWIGGEPVAFTN-GRRGPSQRSKLGKSCVLVQRQ-GKWQTKD 2164
K FWIGLN A WEW +P+ F N PS + G SC + + G WQ+
Sbjct: 272 IAKIFWIGLNQLYSARGWEWSDHKPLNFLNWDPDRPSAPTIGGSSCARMDAESGLWQSFS 331
Query: 2165 CRRAKPHNYVCSRKL 2179
C P YVC + L
Sbjct: 332 CEAQLP--YVCRKPL 344
Score = 48.1 bits (113), Expect = 9e-05
Identities = 40/170 (23%), Positives = 73/170 (42%), Gaps = 19/170 (11%)
Query: 2024 EEGIQKLYQCNG-IAWKAWSPQTKDVE--------DKSCPAGWHQHSGYCHILITEQKGT 2074
E G+ + + C + + P VE D C AGW ++G+C++L+ E +
Sbjct: 323 ESGLWQSFSCEAQLPYVCRKPLNNTVELTDVWTYSDTRCDAGWLPNNGFCYLLVNE-SNS 381
Query: 2075 WNAAAQACREQYLGNLVTVFSRQHMR----WLWDIGGRKSFWIGLNDQVHAGHWEWIGGE 2130
W+ A C+ + +L+++ S + L + ++ WIGL + ++W G
Sbjct: 382 WDKAHAKCK-AFSSDLISIHSLADVEVVVTKLHNEDIKEEVWIGLKNINIPTLFQWSDGT 440
Query: 2131 PVAFTN-GRRGPSQRSKLGKSCV-LVQRQGKWQTKDCRRAKPHNYVCSRK 2178
V T P+ +CV + G+W+ + C + YVC RK
Sbjct: 441 EVTLTYWDENEPNVPYNKTPNCVSYLGELGQWKVQSCE--EKLKYVCKRK 488
Score = 45.1 bits (105), Expect = 8e-04
Identities = 38/131 (29%), Positives = 56/131 (42%), Gaps = 21/131 (16%)
Query: 2050 DKSCPA--GWHQHSGYCHILITEQK--GTWNAAAQACR--EQYLGNLVTVFSRQHMRWLW 2103
DK CP GW +H C+ + ++ GT R ++YL +L+ + +
Sbjct: 498 DKMCPPDEGWKRHGETCYKIYEDEVPFGTNCNLTITSRFEQEYLNDLMKKYDKSL----- 552
Query: 2104 DIGGRKSFWIGLNDQVHAGHWEW--IGGEPVAFTNGRRGPSQRSKLGKSCVLV---QRQG 2158
RK FW GL D G + W +GG A T + + G CV + + G
Sbjct: 553 ----RKYFWTGLRDVDSCGEYNWATVGGRRRAVTFSNWNFLEPASPG-GCVAMSTGKSVG 607
Query: 2159 KWQTKDCRRAK 2169
KW+ KDCR K
Sbjct: 608 KWEVKDCRSFK 618
Score = 39.3 bits (90), Expect = 0.043
Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 17/109 (15%)
Query: 2068 ITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGRKSF--WIGLNDQVHAGH-- 2123
+ ++K TW A C Q G+L +V ++ +L DI R F W+GL+ H G
Sbjct: 1408 VIQKKVTWYEALNMC-SQSGGHLASVHNQNGQLFLEDIVKRDGFPLWVGLSS--HDGSES 1464
Query: 2124 -WEWIGGEPVAFT--NGRRGPSQRSKLGKSCVLVQRQGKWQTKDCRRAK 2169
+EW G + G+ P +CVL+ +G W+ + C K
Sbjct: 1465 SFEWSDGSTFDYIPWKGQTSPG-------NCVLLDPKGTWKHEKCNSVK 1506
Score = 35.8 bits (81), Expect = 0.47
Identities = 25/99 (25%), Positives = 44/99 (44%), Gaps = 7/99 (7%)
Query: 2074 TWNAAAQACREQYLGNLVTVFSRQHMRWL--WDIGGRKSFWIGLNDQVHAGHWEWIGGEP 2131
TW++A + C + + LV++ +L + S WIGL Q ++ W G+
Sbjct: 1123 TWHSAKRECLKSNM-QLVSITDPYQQAFLSVQALLHNSSLWIGLFSQDDELNFGWSDGKR 1181
Query: 2132 VAFTNGRRGPSQRSKLGKSCVLVQRQGKWQTKDCRRAKP 2170
+ F+ Q + CV++ G W+T DC +P
Sbjct: 1182 LHFSRWAETNGQL----EDCVVLDTDGFWKTVDCNDNQP 1216
Score = 34.3 bits (77), Expect = 1.4
Identities = 23/125 (18%), Positives = 51/125 (40%), Gaps = 15/125 (12%)
Query: 2053 CPAG------WHQHSGYCHILITEQKGTWNAAAQAC-REQYLGNLVTVFSRQHMRWLWDI 2105
CPA W Q+ G+C+ + +++ A + C + + +V++ +++ +
Sbjct: 1529 CPAAKENGSRWIQYKGHCY-KSDQALHSFSEAKKLCSKHDHSATIVSIKDEDENKFVSRL 1587
Query: 2106 GGRKS-----FWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKW 2160
+ W+GL+ W W+ G V F +S +G+ +L+ W
Sbjct: 1588 MRENNNITMRVWLGLSQHSVDQSWSWLDGSEVTFVKWEN--KSKSGVGRCSMLIASNETW 1645
Query: 2161 QTKDC 2165
+ +C
Sbjct: 1646 KKVEC 1650
Score = 32.0 bits (71), Expect = 6.8
Identities = 25/85 (29%), Positives = 30/85 (35%), Gaps = 16/85 (18%)
Query: 2050 DKSCPAGWHQHSGYC------HILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLW 2103
D CP GW H +K W A + C Q LG ++ FS
Sbjct: 640 DDPCPEGWQSFPASLSCYKVFHAERIVRKRNWEEAERFC--QALGAHLSSFSH------- 690
Query: 2104 DIGGRKSFWIGLNDQVHAGHWEWIG 2128
+ K F L DQ HW WIG
Sbjct: 691 -VDEIKEFLHFLTDQFSGQHWLWIG 714
>gi|18641360 collectin sub-family member 12 [Homo sapiens]
Length = 742
Score = 57.8 bits (138), Expect = 1e-07
Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 9/134 (6%)
Query: 2049 EDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLW-DIGG 2107
ED CP W + C+ E K + A C ++ +LV + +R+ +W+ + G
Sbjct: 603 EDNGCPPHWKNFTDKCYYFSVE-KEIFEDAKLFCEDKS-SHLVFINTREEQQWIKKQMVG 660
Query: 2108 RKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQR----SKLGKSCVLVQRQGKWQTK 2163
R+S WIGL D W+W+ G + N + G G+ C + G+W
Sbjct: 661 RESHWIGLTDSERENEWKWLDGTSPDYKNWKAGQPDNWGHGHGPGEDCAGLIYAGQWNDF 720
Query: 2164 DCRRAKPHNYVCSR 2177
C +N++C +
Sbjct: 721 QCEDV--NNFICEK 732
>gi|20149533 Fc fragment of IgE, low affinity II, receptor for (CD23A)
[Homo sapiens]
Length = 321
Score = 56.6 bits (135), Expect = 3e-07
Identities = 40/129 (31%), Positives = 60/129 (46%), Gaps = 9/129 (6%)
Query: 2052 SCPAGWHQHSGYCHILITEQKGT--WNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGRK 2109
+CP W C+ KGT W A AC + G LV++ S + +L
Sbjct: 162 TCPEKWINFQRKCYYF---GKGTKQWVHARYACDDME-GQLVSIHSPEEQDFLTKHASHT 217
Query: 2110 SFWIGLNDQVHAGHWEWIGGEPVAFTNGRRG-PSQRSKLGKSCVLVQRQGKWQTKDCRRA 2168
WIGL + G + W+ G V ++N G P+ RS+ G+ CV+++ G+W C R
Sbjct: 218 GSWIGLRNLDLKGEFIWVDGSHVDYSNWAPGEPTSRSQ-GEDCVMMRGSGRWNDAFCDR- 275
Query: 2169 KPHNYVCSR 2177
K +VC R
Sbjct: 276 KLGAWVCDR 284
>gi|10835248 regenerating islet-derived 1 beta precursor [Homo
sapiens]
Length = 166
Score = 55.8 bits (133), Expect = 4e-07
Identities = 37/134 (27%), Positives = 56/134 (41%), Gaps = 10/134 (7%)
Query: 2052 SCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGRKS- 2110
SCP G + + YC+ E TW A C+ GNLV+V ++ ++ + S
Sbjct: 35 SCPEGTNAYRSYCYYF-NEDPETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESST 93
Query: 2111 ----FWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQG--KWQTKD 2164
WIGL+D W W G V++ + G + G L G KW+ +
Sbjct: 94 DDSNVWIGLHDPKKNRRWHWSSGSLVSYKSWDTGSPSSANAGYCASLTSCSGFKKWKDES 153
Query: 2165 CRRAKPHNYVCSRK 2178
C K ++VC K
Sbjct: 154 CE--KKFSFVCKFK 165
>gi|110624774 mannose receptor, C type 2 [Homo sapiens]
Length = 1479
Score = 55.5 bits (132), Expect = 6e-07
Identities = 46/184 (25%), Positives = 75/184 (40%), Gaps = 16/184 (8%)
Query: 2008 SFPKNCTLELKGLFHFEEGIQKLYQCNGIAWKAWSPQT-KD-------VEDKSCPAGWH- 2058
S K CT+ K + G + +G W A + KD ++ C W
Sbjct: 182 SHGKPCTIPFKYDNQWFHGCTSTGREDGHLWCATTQDYGKDERWGFCPIKSNDCETFWDK 241
Query: 2059 -QHSGYCHILITEQKGTWNAAAQACREQY--LGNLVTVFSRQHMRWLWDIGGRKSFWIGL 2115
Q + C+ + +W A +C +Q L ++ + + ++ L G + WIGL
Sbjct: 242 DQLTDSCYQFNFQSTLSWREAWASCEQQGADLLSITEIHEQTYINGLLT-GYSSTLWIGL 300
Query: 2116 NDQVHAGHWEWIGGEPVAFTNGRRG-PSQRSKLGKSCVLVQRQGKWQTKDCRRAKPHNYV 2174
ND +G W+W P+ + N P S+ + + G WQ +DC A P YV
Sbjct: 301 NDLDTSGGWQWSDNSPLKYLNWESDQPDNPSEENCGVIRTESSGGWQNRDCSIALP--YV 358
Query: 2175 CSRK 2178
C +K
Sbjct: 359 CKKK 362
Score = 52.8 bits (125), Expect = 4e-06
Identities = 39/140 (27%), Positives = 64/140 (45%), Gaps = 17/140 (12%)
Query: 2049 EDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWL------ 2102
ED C GW HS C+ L E + T++ A + C + + LVT+ +R ++
Sbjct: 517 EDHGCRKGWTWHSPSCYWL-GEDQVTYSEARRLCTD-HGSQLVTITNRFEQAFVSSLIYN 574
Query: 2103 WDIGGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLV---QRQGK 2159
W+ + FW L D G + W+ G+ V +T+ R S+ G CV + G
Sbjct: 575 WE---GEYFWTALQDLNSTGSFFWLSGDEVMYTHWNRDQPGYSRGG--CVALATGSAMGL 629
Query: 2160 WQTKDCRRAKPHNYVCSRKL 2179
W+ K+C + Y+C + L
Sbjct: 630 WEVKNCTSFRA-RYICRQSL 648
Score = 47.8 bits (112), Expect = 1e-04
Identities = 32/122 (26%), Positives = 58/122 (47%), Gaps = 6/122 (4%)
Query: 2053 CPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGRK--S 2110
C W G+C+ L E++ +W + +AC G+LV++ S + ++ ++
Sbjct: 382 CEPSWQPFQGHCYRLQAEKR-SWQESKKACLRGG-GDLVSIHSMAELEFITKQIKQEVEE 439
Query: 2111 FWIGLNDQVHAGHWEWIGGEPVAFTNGRR-GPSQRSKLGKSCVLV-QRQGKWQTKDCRRA 2168
WIGLND ++EW G V+FT+ P+ + CV + +G+W C ++
Sbjct: 440 LWIGLNDLKLQMNFEWSDGSLVSFTHWHPFEPNNFRDSLEDCVTIWGPEGRWNDSPCNQS 499
Query: 2169 KP 2170
P
Sbjct: 500 LP 501
Score = 37.7 bits (86), Expect = 0.12
Identities = 28/115 (24%), Positives = 46/115 (40%), Gaps = 10/115 (8%)
Query: 2070 EQKGTWNAAAQACREQYLGNLVTVFSRQHMRWL------WDIGGRKSFWIGLNDQVHAGH 2123
E TW A + C + L +V S+ + +L + + +WIGL+ G
Sbjct: 841 EHHSTWAQAQRICT-WFQAELTSVHSQAELDFLSHNLQKFSRAQEQHWWIGLHTSESDGR 899
Query: 2124 WEWIGGEPVAFTNGRRGPSQRSKLGKSCV-LVQRQGKWQTKDCRRAKPHNYVCSR 2177
+ W G + F + G + K CV + + W + C A P Y+C R
Sbjct: 900 FRWTDGSIINFISWAPGKPRPVGKDKKCVYMTASREDWGDQRCLTALP--YICKR 952
Score = 35.8 bits (81), Expect = 0.47
Identities = 17/60 (28%), Positives = 26/60 (43%), Gaps = 3/60 (5%)
Query: 2106 GGRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKWQTKDC 2165
G R WIGL + + + W+ EP+ + + G Q+ C V G W+T C
Sbjct: 1178 GLRTPLWIGLAGEEGSRRYSWVSEEPLNYVGWQDGEPQQP---GGCTYVDVDGAWRTTSC 1234
Score = 34.7 bits (78), Expect = 1.1
Identities = 34/135 (25%), Positives = 54/135 (40%), Gaps = 23/135 (17%)
Query: 2052 SCPAGWHQHSG--YCHILITEQ----KGTWNAAAQACREQYLG-NLVTVFSRQHMRWLW- 2103
SCP GW + YC+ + + + K +W A AC+E LG L+++ S + ++
Sbjct: 668 SCPQGWASDTKLRYCYKVFSSERLQDKKSWVQAQGACQE--LGAQLLSLASYEEEHFVAN 725
Query: 2104 -----------DIGGRKSFWIGLNDQVHAG--HWEWIGGEPVAFTNGRRGPSQRSKLGKS 2150
+I + FWIGLN + G W W G ++ N R +
Sbjct: 726 MLNKIFGESEPEIHEQHWFWIGLNRRDPRGGQSWRWSDGVGFSYHNFDRSRHDDDDIRGC 785
Query: 2151 CVLVQRQGKWQTKDC 2165
VL +W C
Sbjct: 786 AVLDLASLQWVAMQC 800
>gi|33667103 C-type lectin, superfamily member 14 isoform 1 [Homo
sapiens]
Length = 316
Score = 52.4 bits (124), Expect = 5e-06
Identities = 38/138 (27%), Positives = 61/138 (44%), Gaps = 13/138 (9%)
Query: 2049 EDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGR 2108
E CP W +H C+ + +W A + C+ + +LV + SR+ ++ G
Sbjct: 177 EGTCCPVNWVEHQDSCY-WFSHSGMSWAEAEKYCQLKN-AHLVVINSREEQNFVQKYLGS 234
Query: 2109 KSFWIGLNDQVHAGHWEWIGGEPVA--FTNGRRGPS---QRSKL--GKSCVLVQRQGKWQ 2161
W+GL+D G W+W+ G A F N + G Q L G+ C G+W
Sbjct: 235 AYTWMGLSDP--EGAWKWVDGTDYATGFQNWKPGQPDDWQGHGLGGGEDCAHFHPDGRWN 292
Query: 2162 TKDCRRAKPHNYVCSRKL 2179
C+R P+++VC L
Sbjct: 293 DDVCQR--PYHWVCEAGL 308
>gi|53832016 C-type lectin, superfamily member 14 isoform 2 [Homo
sapiens]
Length = 292
Score = 52.4 bits (124), Expect = 5e-06
Identities = 38/138 (27%), Positives = 61/138 (44%), Gaps = 13/138 (9%)
Query: 2049 EDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGR 2108
E CP W +H C+ + +W A + C+ + +LV + SR+ ++ G
Sbjct: 153 EGTCCPVNWVEHQDSCY-WFSHSGMSWAEAEKYCQLKN-AHLVVINSREEQNFVQKYLGS 210
Query: 2109 KSFWIGLNDQVHAGHWEWIGGEPVA--FTNGRRGPS---QRSKL--GKSCVLVQRQGKWQ 2161
W+GL+D G W+W+ G A F N + G Q L G+ C G+W
Sbjct: 211 AYTWMGLSDP--EGAWKWVDGTDYATGFQNWKPGQPDDWQGHGLGGGEDCAHFHPDGRWN 268
Query: 2162 TKDCRRAKPHNYVCSRKL 2179
C+R P+++VC L
Sbjct: 269 DDVCQR--PYHWVCEAGL 284
>gi|113722120 G protein-coupled receptor 98 precursor [Homo sapiens]
Length = 6306
Score = 52.0 bits (123), Expect = 6e-06
Identities = 40/125 (32%), Positives = 59/125 (47%), Gaps = 4/125 (3%)
Query: 1743 IEWSQTEYEVCENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQFDP 1802
IEW Q+ +EV E G L L R + + + + A VG D+ P ++ F
Sbjct: 2962 IEWQQSRFEVNETHGSLTLVAQRSREPLGHVSLFVYAQNLEAQVGLDYIFTP-MILHFAD 3020
Query: 1803 GMSTKMWNIAITYDGLEEDDEVFEVILNSPVNAV-LGTKTKAAVKILDSKGGQCHPSYSS 1861
G K NI I D + E DE F++IL +P + LG T A + +L + G S+
Sbjct: 3021 GERYKNVNIMILDDDIPEGDEKFQLILTNPSPGLELGKNTIALIIVLANDDGPGVLSF-- 3078
Query: 1862 NQSKH 1866
N S+H
Sbjct: 3079 NNSEH 3083
Score = 35.0 bits (79), Expect = 0.80
Identities = 27/104 (25%), Positives = 45/104 (43%), Gaps = 1/104 (0%)
Query: 1748 TEYEVCENVGLLPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQFDPGMSTK 1807
T +EV E+VGL+ + ++R + SA+ G ++ + F G +
Sbjct: 4407 TAFEVEEDVGLIMIPVVRLHGTYGYVTADFISQSSSASPGGVDYILHGSTVTFQHGQNLS 4466
Query: 1808 MWNIAITYDGLEEDDEVFEVILNSPV-NAVLGTKTKAAVKILDS 1850
NI+I D E +E E++L AVLG + + I S
Sbjct: 4467 FINISIIDDNESEFEEPIEILLTGATGGAVLGRHLVSRIIIAKS 4510
Score = 34.7 bits (78), Expect = 1.1
Identities = 22/93 (23%), Positives = 44/93 (47%), Gaps = 1/93 (1%)
Query: 1759 LPLEIIRRGYSMDSAFVGIKVNQVSAAVGKDFTVIPSKLIQFDPGMSTKMWNIAITYDGL 1818
+PL +IR + V +V +D + + I F PG +T ++N+ + D +
Sbjct: 167 MPLTLIREKGTYGMVMVTFEVEGGPNPPDEDLSPVKGN-ITFPPGRATVIYNLTVLDDEV 225
Query: 1819 EEDDEVFEVILNSPVNAVLGTKTKAAVKILDSK 1851
E+DE+F + L S ++ +++I+ K
Sbjct: 226 PENDEIFLIQLKSVEGGAEINTSRNSIEIIIKK 258
>gi|29725633 regenerating islet-derived 1 alpha precursor [Homo
sapiens]
Length = 166
Score = 52.0 bits (123), Expect = 6e-06
Identities = 36/132 (27%), Positives = 54/132 (40%), Gaps = 6/132 (4%)
Query: 2052 SCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDI---GGR 2108
SCP G + + YC+ E + TW A C+ GNLV+V ++ ++ + G
Sbjct: 35 SCPEGTNAYRSYCYYF-NEDRETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGT 93
Query: 2109 KSF--WIGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKWQTKDCR 2166
F WIGL+D W W G V++ + G G L G + KD
Sbjct: 94 DDFNVWIGLHDPKKNRRWHWSSGSLVSYKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVP 153
Query: 2167 RAKPHNYVCSRK 2178
++VC K
Sbjct: 154 CEDKFSFVCKFK 165
>gi|4502251 asialoglycoprotein receptor 1 [Homo sapiens]
Length = 291
Score = 52.0 bits (123), Expect = 6e-06
Identities = 40/140 (28%), Positives = 59/140 (42%), Gaps = 17/140 (12%)
Query: 2049 EDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGR 2108
E CP W +H C+ K W A CR + +LV V S + +++ G
Sbjct: 150 ERTCCPVNWVEHERSCYWFSRSGKA-WADADNYCRLED-AHLVVVTSWEEQKFVQHHIGP 207
Query: 2109 KSFWIGLNDQVHAGHWEWIGGE--PVAFTNGRRGPSQRSKL-------GKSCVLVQRQGK 2159
+ W+GL+DQ G W+W+ G F N R P Q G+ C G+
Sbjct: 208 VNTWMGLHDQ--NGPWKWVDGTDYETGFKNWR--PEQPDDWYGHGLGGGEDCAHFTDDGR 263
Query: 2160 WQTKDCRRAKPHNYVCSRKL 2179
W C+R P+ +VC +L
Sbjct: 264 WNDDVCQR--PYRWVCETEL 281
>gi|38348296 C-type lectin domain family 4, member G [Homo sapiens]
Length = 293
Score = 51.6 bits (122), Expect = 8e-06
Identities = 31/129 (24%), Positives = 56/129 (43%), Gaps = 6/129 (4%)
Query: 2053 CPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGRKSFW 2112
CP W G C+ + K TW AA C + +LV V +L + +W
Sbjct: 165 CPTSWLSFEGSCYFF-SVPKTTWAAAQDHCADAS-AHLVIVGGLDEQGFLTRNTRGRGYW 222
Query: 2113 IGLNDQVHAGH---WEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQGKWQTKDCRRAK 2169
+GL H G ++W+ G ++F++ +G + ++CV++ G W C K
Sbjct: 223 LGLRAVRHLGKVQGYQWVDGVSLSFSHWNQGEPNDAWGRENCVMMLHTGLWNDAPCDSEK 282
Query: 2170 PHNYVCSRK 2178
++C ++
Sbjct: 283 -DGWICEKR 290
>gi|38372935 brevican isoform 1 [Homo sapiens]
Length = 911
Score = 51.2 bits (121), Expect = 1e-05
Identities = 34/122 (27%), Positives = 58/122 (47%), Gaps = 6/122 (4%)
Query: 2047 DVEDKSCPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIG 2106
DV + C GW G C+ + ++ +W A CR Y +L ++ + + ++ +
Sbjct: 682 DVGLRFCNPGWDAFQGACYKHFSTRR-SWEEAETQCR-MYGAHLASISTPEEQDFI-NNR 738
Query: 2107 GRKSFWIGLNDQVHAGHWEWIGGEPVAFTNGRRG-PSQRSKLGKSCVLV--QRQGKWQTK 2163
R+ WIGLND+ G + W G P+ + N G P G++CV++ QG+W
Sbjct: 739 YREYQWIGLNDRTIEGDFLWSDGVPLLYENWNPGQPDSYFLSGENCVVMVWHDQGQWSDV 798
Query: 2164 DC 2165
C
Sbjct: 799 PC 800
>gi|21070995 pancreatitis-associated protein precursor [Homo sapiens]
Length = 175
Score = 50.8 bits (120), Expect = 1e-05
Identities = 40/136 (29%), Positives = 61/136 (44%), Gaps = 17/136 (12%)
Query: 2053 CPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRW----LWDIGGR 2108
CP G + +C+ L K +W A AC+++ GNLV+V S + + IG
Sbjct: 40 CPKGSKAYGSHCYALFLSPK-SWTDADLACQKRPSGNLVSVLSGAEGSFVSSLVKSIGNS 98
Query: 2109 KSF-WIGLND-----QVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQG---K 2159
S+ WIGL+D + + WEW + + + R PS S G C + R +
Sbjct: 99 YSYVWIGLHDPTQGTEPNGEGWEWSSSDVMNYFAWERNPSTISSPG-HCASLSRSTAFLR 157
Query: 2160 WQTKDCRRAKPHNYVC 2175
W+ +C P YVC
Sbjct: 158 WKDYNCNVRLP--YVC 171
>gi|21070993 pancreatitis-associated protein precursor [Homo sapiens]
Length = 175
Score = 50.8 bits (120), Expect = 1e-05
Identities = 40/136 (29%), Positives = 61/136 (44%), Gaps = 17/136 (12%)
Query: 2053 CPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRW----LWDIGGR 2108
CP G + +C+ L K +W A AC+++ GNLV+V S + + IG
Sbjct: 40 CPKGSKAYGSHCYALFLSPK-SWTDADLACQKRPSGNLVSVLSGAEGSFVSSLVKSIGNS 98
Query: 2109 KSF-WIGLND-----QVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQG---K 2159
S+ WIGL+D + + WEW + + + R PS S G C + R +
Sbjct: 99 YSYVWIGLHDPTQGTEPNGEGWEWSSSDVMNYFAWERNPSTISSPG-HCASLSRSTAFLR 157
Query: 2160 WQTKDCRRAKPHNYVC 2175
W+ +C P YVC
Sbjct: 158 WKDYNCNVRLP--YVC 171
>gi|4505605 pancreatitis-associated protein precursor [Homo sapiens]
Length = 175
Score = 50.8 bits (120), Expect = 1e-05
Identities = 40/136 (29%), Positives = 61/136 (44%), Gaps = 17/136 (12%)
Query: 2053 CPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRW----LWDIGGR 2108
CP G + +C+ L K +W A AC+++ GNLV+V S + + IG
Sbjct: 40 CPKGSKAYGSHCYALFLSPK-SWTDADLACQKRPSGNLVSVLSGAEGSFVSSLVKSIGNS 98
Query: 2109 KSF-WIGLND-----QVHAGHWEWIGGEPVAFTNGRRGPSQRSKLGKSCVLVQRQG---K 2159
S+ WIGL+D + + WEW + + + R PS S G C + R +
Sbjct: 99 YSYVWIGLHDPTQGTEPNGEGWEWSSSDVMNYFAWERNPSTISSPG-HCASLSRSTAFLR 157
Query: 2160 WQTKDCRRAKPHNYVC 2175
W+ +C P YVC
Sbjct: 158 WKDYNCNVRLP--YVC 171
>gi|18426877 asialoglycoprotein receptor 2 isoform c [Homo sapiens]
Length = 292
Score = 48.5 bits (114), Expect = 7e-05
Identities = 35/133 (26%), Positives = 57/133 (42%), Gaps = 13/133 (9%)
Query: 2053 CPAGWHQHSGYCHILITEQKGTWNAAAQACREQYLGNLVTVFSRQHMRWLWDIGGRKSFW 2112
CP W +H G C+ K W A + C+ + +LV + S + +++ + W
Sbjct: 158 CPVNWVEHQGSCYWFSHSGK-AWAEAEKYCQLEN-AHLVVINSWEEQKFIVQHTNPFNTW 215
Query: 2113 IGLNDQVHAGHWEWIGGEPVAFTNGRRGPSQRS-----KLGKS--CVLVQRQGKWQTKDC 2165
IGL D G W+W+ G +Q +LG S CV VQ G+W C
Sbjct: 216 IGLTDS--DGSWKWVDGTDYRHNYKNWAVTQPDNWHGHELGGSEDCVEVQPDGRWNDDFC 273
Query: 2166 RRAKPHNYVCSRK 2178
+ + +VC ++
Sbjct: 274 LQV--YRWVCEKR 284
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,836,378
Number of Sequences: 37866
Number of extensions: 4243537
Number of successful extensions: 9652
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 118
Number of HSP's that attempted gapping in prelim test: 8553
Number of HSP's gapped (non-prelim): 427
length of query: 2179
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2061
effective length of database: 13,779,330
effective search space: 28399199130
effective search space used: 28399199130
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.