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Search of human proteins with 24432058
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24432058 aminopeptidase O [Homo sapiens]
(720 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24432058 aminopeptidase O [Homo sapiens] 1472 0.0
gi|40316915 arginyl aminopeptidase [Homo sapiens] 100 6e-21
gi|54020718 arginyl aminopeptidase (aminopeptidase B)-like 1 [Ho... 69 1e-11
gi|4505029 leukotriene A4 hydrolase [Homo sapiens] 49 2e-05
gi|148727333 adenylate kinase 7 [Homo sapiens] 38 0.029
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 34 0.42
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 34 0.42
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 34 0.42
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 34 0.42
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 34 0.42
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 34 0.42
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 34 0.42
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 34 0.42
gi|148529025 pleckstrin homology domain containing, family G (wi... 34 0.42
gi|4507347 TBP-associated factor 2 [Homo sapiens] 34 0.54
gi|148746195 trichohyalin [Homo sapiens] 33 0.92
gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ... 32 1.6
gi|29570800 cadherin-like 26 isoform a [Homo sapiens] 32 1.6
gi|194239713 laeverin [Homo sapiens] 32 2.7
gi|197209826 chromosome 2 open reading frame 21 isoform 1 [Homo ... 31 3.5
gi|70980531 GGA binding partner [Homo sapiens] 30 7.8
>gi|24432058 aminopeptidase O [Homo sapiens]
Length = 720
Score = 1472 bits (3812), Expect = 0.0
Identities = 720/720 (100%), Positives = 720/720 (100%)
Query: 1 MDIQLDPARDDLPLMANTSHILVKHYVLDLDVDFESQVIEGTIVLFLEDGNRFKKQNSSI 60
MDIQLDPARDDLPLMANTSHILVKHYVLDLDVDFESQVIEGTIVLFLEDGNRFKKQNSSI
Sbjct: 1 MDIQLDPARDDLPLMANTSHILVKHYVLDLDVDFESQVIEGTIVLFLEDGNRFKKQNSSI 60
Query: 61 EEACQSESNKACKFGMPEPCHIPVTNARTFSSEMEYNDFAICSKGEKDTSDKDGNHDNQE 120
EEACQSESNKACKFGMPEPCHIPVTNARTFSSEMEYNDFAICSKGEKDTSDKDGNHDNQE
Sbjct: 61 EEACQSESNKACKFGMPEPCHIPVTNARTFSSEMEYNDFAICSKGEKDTSDKDGNHDNQE 120
Query: 121 HASGISSSKYCCDTGNHGSEDFLLVLDCCDLSVLKVEEVDVAAVPGLEKFTRSPELTVVS 180
HASGISSSKYCCDTGNHGSEDFLLVLDCCDLSVLKVEEVDVAAVPGLEKFTRSPELTVVS
Sbjct: 121 HASGISSSKYCCDTGNHGSEDFLLVLDCCDLSVLKVEEVDVAAVPGLEKFTRSPELTVVS 180
Query: 181 EEFRNQIVRELVTLPANRWREQLDYYARCSQAPGCGELLFDTDTWSLQIRKTGAQTATDF 240
EEFRNQIVRELVTLPANRWREQLDYYARCSQAPGCGELLFDTDTWSLQIRKTGAQTATDF
Sbjct: 181 EEFRNQIVRELVTLPANRWREQLDYYARCSQAPGCGELLFDTDTWSLQIRKTGAQTATDF 240
Query: 241 PHAIRIWYKTKPEGRSVTWTSDQSGRPCVYTVGSPINNRALFPCQEPPVAMSTWQATVRA 300
PHAIRIWYKTKPEGRSVTWTSDQSGRPCVYTVGSPINNRALFPCQEPPVAMSTWQATVRA
Sbjct: 241 PHAIRIWYKTKPEGRSVTWTSDQSGRPCVYTVGSPINNRALFPCQEPPVAMSTWQATVRA 300
Query: 301 AASFVVLMSGENSAKPTQLWEECSSWYYYVTMPMPASTFTIAVGCWTEMKMETWSSNDLA 360
AASFVVLMSGENSAKPTQLWEECSSWYYYVTMPMPASTFTIAVGCWTEMKMETWSSNDLA
Sbjct: 301 AASFVVLMSGENSAKPTQLWEECSSWYYYVTMPMPASTFTIAVGCWTEMKMETWSSNDLA 360
Query: 361 TERPFSPSEANFRHVGVCSHMEYPCRFQNASATTQEIIPHRVFAPVCLTGACQETLLRLI 420
TERPFSPSEANFRHVGVCSHMEYPCRFQNASATTQEIIPHRVFAPVCLTGACQETLLRLI
Sbjct: 361 TERPFSPSEANFRHVGVCSHMEYPCRFQNASATTQEIIPHRVFAPVCLTGACQETLLRLI 420
Query: 421 PPCLSAAHSVLGAHPFSRLDVLIVPANFPSLGMARPSKDKTGHTSDSGASVIKHGLNPEK 480
PPCLSAAHSVLGAHPFSRLDVLIVPANFPSLGMARPSKDKTGHTSDSGASVIKHGLNPEK
Sbjct: 421 PPCLSAAHSVLGAHPFSRLDVLIVPANFPSLGMARPSKDKTGHTSDSGASVIKHGLNPEK 480
Query: 481 IFMQVHYLKGYFLLRFLAKRLGDETYFSFLRKFVHTFHGQLILSQDFLQMLLENIPEEKR 540
IFMQVHYLKGYFLLRFLAKRLGDETYFSFLRKFVHTFHGQLILSQDFLQMLLENIPEEKR
Sbjct: 481 IFMQVHYLKGYFLLRFLAKRLGDETYFSFLRKFVHTFHGQLILSQDFLQMLLENIPEEKR 540
Query: 541 LELSVENIYQDWLESSGIPKPLQRERRAGAECGLARQVRAEVTKWIGVNRRPRKRKRREK 600
LELSVENIYQDWLESSGIPKPLQRERRAGAECGLARQVRAEVTKWIGVNRRPRKRKRREK
Sbjct: 541 LELSVENIYQDWLESSGIPKPLQRERRAGAECGLARQVRAEVTKWIGVNRRPRKRKRREK 600
Query: 601 EEVFEKLLPDQLVLLLEHLLEQKTLSPRTLQSLQRTYHLQDQDAEVRHRWCELIVKHKFT 660
EEVFEKLLPDQLVLLLEHLLEQKTLSPRTLQSLQRTYHLQDQDAEVRHRWCELIVKHKFT
Sbjct: 601 EEVFEKLLPDQLVLLLEHLLEQKTLSPRTLQSLQRTYHLQDQDAEVRHRWCELIVKHKFT 660
Query: 661 KAYKSVERFLQEDQAMGVYLYGELMVSEDARQQQLARRCFERTKEQMDRSSAQVVAEMLF 720
KAYKSVERFLQEDQAMGVYLYGELMVSEDARQQQLARRCFERTKEQMDRSSAQVVAEMLF
Sbjct: 661 KAYKSVERFLQEDQAMGVYLYGELMVSEDARQQQLARRCFERTKEQMDRSSAQVVAEMLF 720
>gi|40316915 arginyl aminopeptidase [Homo sapiens]
Length = 650
Score = 100 bits (248), Expect = 6e-21
Identities = 121/534 (22%), Positives = 209/534 (39%), Gaps = 101/534 (18%)
Query: 253 EGRSVTWTSDQSG----RPCVYTVGSPINNRALFPCQEPPVAMSTWQATVRAAASFVVLM 308
EG V W + + +P VYT G + NRA FPC + P + A + F +M
Sbjct: 146 EGPGVCWLAPEQTAGKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVM 205
Query: 309 SGENSAKPTQLWEECSSWYYYVTMPMPASTFTIAVGCWTEMKMETWSSNDLATERPFSPS 368
S WE+ ++ M P ++ IA+ + E + + E P
Sbjct: 206 SAST-------WEKRGPNKFFFQMCQPIPSYLIALAIGDLVSAEVGPRSRVWAE-PCLID 257
Query: 369 EANFRHVGVCSHMEYPCRFQNASATTQEIIPHRVFA--------PVCLTGACQETLLRLI 420
A + GV + AT +++ V+ P G + L +
Sbjct: 258 AAKEEYNGV---------IEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFV 308
Query: 421 PPCLSA-------------AHSVLG------------------AHPFSRLDVLIVPANFP 449
PCL A +HS G + R+ ++ A +
Sbjct: 309 TPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYT 368
Query: 450 SLGMA------RPSKDKTGHTSDSGASVIK--HGLNPEKIFMQVHYLKGYFLLRFLAKRL 501
L A R D TG + +K G++P+ + + Y KG+ + +LA +
Sbjct: 369 CLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLV 428
Query: 502 GDETYF-SFLRKFVHTFHGQLILSQDFLQMLLENIPE--EKRLELSVENIYQDWLESSGI 558
GD+ F SFL+ +VH F + IL+ DFL LE PE +KR+++ + WL + G
Sbjct: 429 GDQDQFDSFLKAYVHEFKFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGW 488
Query: 559 P---------KPLQRERRAGAECGLARQVRAEVTKWIGVNRRPRKRKRREKEEVFEKLLP 609
P L + A+ A ++ + + + ++ P K
Sbjct: 489 PPYLPDLSPGDSLMKPAEELAQLWAAEELDMKAIEAVAIS--PWKTY------------- 533
Query: 610 DQLVLLLEHLLEQKTLSPRTLQSLQRTYH--LQDQDAEVRHRWCELIVKHKFTKAYKSVE 667
QLV L+ +L++ L P ++ L TY ++AE+R RW ++++K+ + + V+
Sbjct: 534 -QLVYFLDKILQKSPLPPGNVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVK 592
Query: 668 RFL--QEDQAMGVYLYGELMVSEDARQQQLARRCFERTKEQMDRSSAQVVAEML 719
FL Q Q + LY +M + Q LA+ F T Q+ + V +++
Sbjct: 593 EFLHNQGKQKYTLPLYHAMMGGSEV-AQTLAKETFASTASQLHSNVVNYVQQIV 645
>gi|54020718 arginyl aminopeptidase (aminopeptidase B)-like 1 [Homo
sapiens]
Length = 494
Score = 69.3 bits (168), Expect = 1e-11
Identities = 64/257 (24%), Positives = 110/257 (42%), Gaps = 19/257 (7%)
Query: 472 IKHGLNPEKIFMQVHYLKGYFLLRFLAKRLGDETYFS-FLRKFVHTFHGQLILSQDFLQM 530
++ G+NP + Y KGY + +L++ GD F FLR +V + +++QD L
Sbjct: 196 LEPGVNPSHLMNLFTYEKGYCFVYYLSQLCGDPQRFDDFLRAYVEKYKFTSVVAQDLLDS 255
Query: 531 LLENIPE--EKRLELSVENIYQDWLESSGIPKPLQRERRAGAECGLARQVRAEVTKWIGV 588
L PE E+ ++ ++ WL ++G P E L R V A W
Sbjct: 256 FLSFFPELKEQSVDCRAGLEFERWLNATGPPLA---EPDLSQGSSLTRPVEALFQLWTA- 311
Query: 589 NRRPRKRKRREKEEV-FEKLLPDQLVLLLEHLLEQKTLSPRTLQSLQRTYH--LQDQDAE 645
P + + K Q L L+ LL+ L + SL + Y L +AE
Sbjct: 312 --EPLDQAAASASAIDISKWRTFQTALFLDRLLDGSPLPQEVVMSLSKCYSSLLDSMNAE 369
Query: 646 VRHRWCELIVKHKFTKAYKSVERFLQEDQAMGVY---LYGELMVSEDARQQQLARRCFER 702
+R RW +++V++ + V RFL E Q +Y LY +L + A F +
Sbjct: 370 IRIRWLQIVVRNDYYPDLHRVRRFL-ESQMSRMYTIPLYEDLCT---GALKSFALEVFYQ 425
Query: 703 TKEQMDRSSAQVVAEML 719
T+ ++ + + + ++L
Sbjct: 426 TQGRLHPNLRRAIQQIL 442
Score = 38.9 bits (89), Expect = 0.017
Identities = 23/83 (27%), Positives = 37/83 (44%), Gaps = 6/83 (7%)
Query: 380 HMEYPCRFQNASATTQEIIP------HRVFAPVCLTGACQETLLRLIPPCLSAAHSVLGA 433
HME+P + ++ P RV+A CL L + LSAA + G
Sbjct: 18 HMEHPVPAYLVALVAGDLKPADIGPRSRVWAEPCLLPTATSKLSGAVEQWLSAAERLYGP 77
Query: 434 HPFSRLDVLIVPANFPSLGMARP 456
+ + R D++ +P +FP + M P
Sbjct: 78 YMWGRYDIVFLPPSFPIVAMENP 100
>gi|4505029 leukotriene A4 hydrolase [Homo sapiens]
Length = 611
Score = 48.5 bits (114), Expect = 2e-05
Identities = 56/248 (22%), Positives = 102/248 (41%), Gaps = 16/248 (6%)
Query: 476 LNPEKIFMQVHYLKGYFLLRFLAKRLGD-ETYFSFLRKFVHTFHGQLILSQDFLQMLLEN 534
++P+ + V Y KG+ LL +L + LG E + FL+ +V F + I + D+ L
Sbjct: 373 IDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSY 432
Query: 535 IPEEKRLELSVENIYQDWLESSGIPKPLQRERRAGAECGLARQVRAEVTKWIGVNRRPRK 594
++ + V+ + WL S G+P P+ + + L A +WI
Sbjct: 433 FKDKVDVLNQVD--WNAWLYSPGLP-PI----KPNYDMTLTNACIALSQRWITAKEDDLN 485
Query: 595 RKRREKEEVFEKLLPDQLVLLLEHLLEQKTLSPRTLQSLQRTYHLQD-QDAEVRHRWCEL 653
+ L QL L L++ L ++ +Q Y+ ++E+R RW L
Sbjct: 486 SFNATD---LKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWLRL 542
Query: 654 IVKHKFTKAYKSVERFLQEDQAMGVY--LYGELMVSEDARQQQLARRCFERTKEQMDRSS 711
++ K+ A + E M L+ +L + + Q A R ++ K M +
Sbjct: 543 CIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQ--AVRTYQEHKASMHPVT 600
Query: 712 AQVVAEML 719
A +V + L
Sbjct: 601 AMLVGKDL 608
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/135 (22%), Positives = 58/135 (42%), Gaps = 9/135 (6%)
Query: 244 IRIWYKTKPEGRSVTWTSDQ--SGR--PCVYTVGSPINNRALFPCQEPPVAMSTWQATVR 299
I I ++T P+ ++ W + + SG+ P +++ I+ RA+ PCQ+ P T+ A V
Sbjct: 103 IEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVS 162
Query: 300 AAASFVVLMSGENSAKPTQLWEECSSWYYYV-TMPMPASTFTIAVGCWTEMKME----TW 354
V LMS + + Y ++ +P+P + VG ++ W
Sbjct: 163 VPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVW 222
Query: 355 SSNDLATERPFSPSE 369
S + + + SE
Sbjct: 223 SEKEQVEKSAYEFSE 237
>gi|148727333 adenylate kinase 7 [Homo sapiens]
Length = 723
Score = 38.1 bits (87), Expect = 0.029
Identities = 46/177 (25%), Positives = 80/177 (45%), Gaps = 20/177 (11%)
Query: 478 PEKIFMQVHYLKGYFLLRFLAKR---LGDETYFSFLRKF-VHTFH---GQLILSQDFL-- 528
PE I HY + FL R + DET F++ + +H H G+L +Q+ L
Sbjct: 539 PESIVAGTHYSQDRFLRALSNYRDINIDDETVFNYFDELEIHPIHIDVGKLEDAQNRLAI 598
Query: 529 QMLLENIPEEKRLELSVENIYQDWLESSGIPKPLQRE--RRAGAECGLARQVRAEVTKWI 586
+ L++ I E + L+ E ++ E + L RE A E A ++ ++ +W
Sbjct: 599 KQLIKEIGEPRNYGLTDEEKAEE--ERKAAEERLAREAAEEAEREHQEAVEMAEKIARWE 656
Query: 587 GVNRRPRKRKRREKEEVFEKLLPDQLVLLLEHLLEQKTLSPRTLQSLQRTYHLQDQD 643
N+R + KR E+E LL Q + L +L+ + P +Q L +++ +D
Sbjct: 657 EWNKRLEEVKREERE-----LLEAQSIPLRNYLMTY--VMPTLIQGLNECCNVRPED 706
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 34.3 bits (77), Expect = 0.42
Identities = 53/224 (23%), Positives = 92/224 (41%), Gaps = 32/224 (14%)
Query: 526 DFLQMLLENIPEE-KRLELSVENIYQDWLESS-GIPKPLQRERRAGAECGL-ARQVRAEV 582
+ LQ E E+ +RL+ E + Q E + G + L+ ER+ E A +++ V
Sbjct: 2330 ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV 2389
Query: 583 TKWIGVNRRPRK---RKRREKEEVFEKLLPDQL-----VLLLEHLLEQKTLSPRTLQSLQ 634
+ R + R R++ EE+ EKL +L V L++ L Q+ S + L+
Sbjct: 2390 AEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLR 2449
Query: 635 RTYHLQDQDAEVRHRWCELIVKHKFTKAYKSVERFLQEDQAMGVYLYGE----------- 683
+++ E + +L+ E+ LQE QA+ E
Sbjct: 2450 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI 2509
Query: 684 ---------LMVSEDARQQQLARRCFERTKEQMDRSSAQVVAEM 718
L E A+ QQL R +R ++QM++ ++VA M
Sbjct: 2510 EQEKAKLEQLFQDEVAKAQQL-REEQQRQQQQMEQERQRLVASM 2552
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 34.3 bits (77), Expect = 0.42
Identities = 53/224 (23%), Positives = 92/224 (41%), Gaps = 32/224 (14%)
Query: 526 DFLQMLLENIPEE-KRLELSVENIYQDWLESS-GIPKPLQRERRAGAECGL-ARQVRAEV 582
+ LQ E E+ +RL+ E + Q E + G + L+ ER+ E A +++ V
Sbjct: 2334 ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV 2393
Query: 583 TKWIGVNRRPRK---RKRREKEEVFEKLLPDQL-----VLLLEHLLEQKTLSPRTLQSLQ 634
+ R + R R++ EE+ EKL +L V L++ L Q+ S + L+
Sbjct: 2394 AEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLR 2453
Query: 635 RTYHLQDQDAEVRHRWCELIVKHKFTKAYKSVERFLQEDQAMGVYLYGE----------- 683
+++ E + +L+ E+ LQE QA+ E
Sbjct: 2454 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI 2513
Query: 684 ---------LMVSEDARQQQLARRCFERTKEQMDRSSAQVVAEM 718
L E A+ QQL R +R ++QM++ ++VA M
Sbjct: 2514 EQEKAKLEQLFQDEVAKAQQL-REEQQRQQQQMEQERQRLVASM 2556
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 34.3 bits (77), Expect = 0.42
Identities = 53/224 (23%), Positives = 92/224 (41%), Gaps = 32/224 (14%)
Query: 526 DFLQMLLENIPEE-KRLELSVENIYQDWLESS-GIPKPLQRERRAGAECGL-ARQVRAEV 582
+ LQ E E+ +RL+ E + Q E + G + L+ ER+ E A +++ V
Sbjct: 2330 ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV 2389
Query: 583 TKWIGVNRRPRK---RKRREKEEVFEKLLPDQL-----VLLLEHLLEQKTLSPRTLQSLQ 634
+ R + R R++ EE+ EKL +L V L++ L Q+ S + L+
Sbjct: 2390 AEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLR 2449
Query: 635 RTYHLQDQDAEVRHRWCELIVKHKFTKAYKSVERFLQEDQAMGVYLYGE----------- 683
+++ E + +L+ E+ LQE QA+ E
Sbjct: 2450 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI 2509
Query: 684 ---------LMVSEDARQQQLARRCFERTKEQMDRSSAQVVAEM 718
L E A+ QQL R +R ++QM++ ++VA M
Sbjct: 2510 EQEKAKLEQLFQDEVAKAQQL-REEQQRQQQQMEQERQRLVASM 2552
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 34.3 bits (77), Expect = 0.42
Identities = 53/224 (23%), Positives = 92/224 (41%), Gaps = 32/224 (14%)
Query: 526 DFLQMLLENIPEE-KRLELSVENIYQDWLESS-GIPKPLQRERRAGAECGL-ARQVRAEV 582
+ LQ E E+ +RL+ E + Q E + G + L+ ER+ E A +++ V
Sbjct: 2298 ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV 2357
Query: 583 TKWIGVNRRPRK---RKRREKEEVFEKLLPDQL-----VLLLEHLLEQKTLSPRTLQSLQ 634
+ R + R R++ EE+ EKL +L V L++ L Q+ S + L+
Sbjct: 2358 AEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLR 2417
Query: 635 RTYHLQDQDAEVRHRWCELIVKHKFTKAYKSVERFLQEDQAMGVYLYGE----------- 683
+++ E + +L+ E+ LQE QA+ E
Sbjct: 2418 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI 2477
Query: 684 ---------LMVSEDARQQQLARRCFERTKEQMDRSSAQVVAEM 718
L E A+ QQL R +R ++QM++ ++VA M
Sbjct: 2478 EQEKAKLEQLFQDEVAKAQQL-REEQQRQQQQMEQERQRLVASM 2520
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 34.3 bits (77), Expect = 0.42
Identities = 53/224 (23%), Positives = 92/224 (41%), Gaps = 32/224 (14%)
Query: 526 DFLQMLLENIPEE-KRLELSVENIYQDWLESS-GIPKPLQRERRAGAECGL-ARQVRAEV 582
+ LQ E E+ +RL+ E + Q E + G + L+ ER+ E A +++ V
Sbjct: 2467 ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV 2526
Query: 583 TKWIGVNRRPRK---RKRREKEEVFEKLLPDQL-----VLLLEHLLEQKTLSPRTLQSLQ 634
+ R + R R++ EE+ EKL +L V L++ L Q+ S + L+
Sbjct: 2527 AEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLR 2586
Query: 635 RTYHLQDQDAEVRHRWCELIVKHKFTKAYKSVERFLQEDQAMGVYLYGE----------- 683
+++ E + +L+ E+ LQE QA+ E
Sbjct: 2587 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI 2646
Query: 684 ---------LMVSEDARQQQLARRCFERTKEQMDRSSAQVVAEM 718
L E A+ QQL R +R ++QM++ ++VA M
Sbjct: 2647 EQEKAKLEQLFQDEVAKAQQL-REEQQRQQQQMEQERQRLVASM 2689
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 34.3 bits (77), Expect = 0.42
Identities = 53/224 (23%), Positives = 92/224 (41%), Gaps = 32/224 (14%)
Query: 526 DFLQMLLENIPEE-KRLELSVENIYQDWLESS-GIPKPLQRERRAGAECGL-ARQVRAEV 582
+ LQ E E+ +RL+ E + Q E + G + L+ ER+ E A +++ V
Sbjct: 2308 ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV 2367
Query: 583 TKWIGVNRRPRK---RKRREKEEVFEKLLPDQL-----VLLLEHLLEQKTLSPRTLQSLQ 634
+ R + R R++ EE+ EKL +L V L++ L Q+ S + L+
Sbjct: 2368 AEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLR 2427
Query: 635 RTYHLQDQDAEVRHRWCELIVKHKFTKAYKSVERFLQEDQAMGVYLYGE----------- 683
+++ E + +L+ E+ LQE QA+ E
Sbjct: 2428 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI 2487
Query: 684 ---------LMVSEDARQQQLARRCFERTKEQMDRSSAQVVAEM 718
L E A+ QQL R +R ++QM++ ++VA M
Sbjct: 2488 EQEKAKLEQLFQDEVAKAQQL-REEQQRQQQQMEQERQRLVASM 2530
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 34.3 bits (77), Expect = 0.42
Identities = 53/224 (23%), Positives = 92/224 (41%), Gaps = 32/224 (14%)
Query: 526 DFLQMLLENIPEE-KRLELSVENIYQDWLESS-GIPKPLQRERRAGAECGL-ARQVRAEV 582
+ LQ E E+ +RL+ E + Q E + G + L+ ER+ E A +++ V
Sbjct: 2316 ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV 2375
Query: 583 TKWIGVNRRPRK---RKRREKEEVFEKLLPDQL-----VLLLEHLLEQKTLSPRTLQSLQ 634
+ R + R R++ EE+ EKL +L V L++ L Q+ S + L+
Sbjct: 2376 AEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLR 2435
Query: 635 RTYHLQDQDAEVRHRWCELIVKHKFTKAYKSVERFLQEDQAMGVYLYGE----------- 683
+++ E + +L+ E+ LQE QA+ E
Sbjct: 2436 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI 2495
Query: 684 ---------LMVSEDARQQQLARRCFERTKEQMDRSSAQVVAEM 718
L E A+ QQL R +R ++QM++ ++VA M
Sbjct: 2496 EQEKAKLEQLFQDEVAKAQQL-REEQQRQQQQMEQERQRLVASM 2538
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 34.3 bits (77), Expect = 0.42
Identities = 53/224 (23%), Positives = 92/224 (41%), Gaps = 32/224 (14%)
Query: 526 DFLQMLLENIPEE-KRLELSVENIYQDWLESS-GIPKPLQRERRAGAECGL-ARQVRAEV 582
+ LQ E E+ +RL+ E + Q E + G + L+ ER+ E A +++ V
Sbjct: 2357 ELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRV 2416
Query: 583 TKWIGVNRRPRK---RKRREKEEVFEKLLPDQL-----VLLLEHLLEQKTLSPRTLQSLQ 634
+ R + R R++ EE+ EKL +L V L++ L Q+ S + L+
Sbjct: 2417 AEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLR 2476
Query: 635 RTYHLQDQDAEVRHRWCELIVKHKFTKAYKSVERFLQEDQAMGVYLYGE----------- 683
+++ E + +L+ E+ LQE QA+ E
Sbjct: 2477 EAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFI 2536
Query: 684 ---------LMVSEDARQQQLARRCFERTKEQMDRSSAQVVAEM 718
L E A+ QQL R +R ++QM++ ++VA M
Sbjct: 2537 EQEKAKLEQLFQDEVAKAQQL-REEQQRQQQQMEQERQRLVASM 2579
>gi|148529025 pleckstrin homology domain containing, family G (with
RhoGef domain) member 4B [Homo sapiens]
Length = 1271
Score = 34.3 bits (77), Expect = 0.42
Identities = 19/51 (37%), Positives = 29/51 (56%)
Query: 628 RTLQSLQRTYHLQDQDAEVRHRWCELIVKHKFTKAYKSVERFLQEDQAMGV 678
R + Q TY LQ AEV+ W ++I + + +A KS E +QE +MG+
Sbjct: 1073 RRRRKSQDTYILQASSAEVKSAWTDVIGRILWRQALKSRELRIQEMASMGI 1123
>gi|4507347 TBP-associated factor 2 [Homo sapiens]
Length = 1199
Score = 33.9 bits (76), Expect = 0.54
Identities = 18/76 (23%), Positives = 36/76 (47%)
Query: 269 VYTVGSPINNRALFPCQEPPVAMSTWQATVRAAASFVVLMSGENSAKPTQLWEECSSWYY 328
V++ G + R FPC + + TW+ A+ V + +G+ +++Y
Sbjct: 177 VFSCGYQNSTRFWFPCVDSYSELCTWKLEFTVDAAMVAVSNGDLVETVYTHDMRKKTFHY 236
Query: 329 YVTMPMPASTFTIAVG 344
+T+P AS ++A+G
Sbjct: 237 MLTIPTAASNISLAIG 252
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 33.1 bits (74), Expect = 0.92
Identities = 41/185 (22%), Positives = 83/185 (44%), Gaps = 17/185 (9%)
Query: 537 EEKRLELSVENIYQDWLESSGIPKPLQRERRAGAECGLARQVRAEVTKWIGVNRRPRKRK 596
E++R E + Q+ E + + ++ RR E + + + + + P KR+
Sbjct: 925 EQERQYREEEQLQQE--EEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRR 982
Query: 597 RREKEEVFEKLLPDQLVLLLEHLLEQKTLSPRTLQSLQRTY----HLQDQDAEVRHRWCE 652
R+E+E+ + + ++L E LL ++ R Q +R Y LQ ++ ++ E
Sbjct: 983 RQEREKKYRE--EEELQQEEEQLLREER-EKRRRQEWERQYRKKDELQQEEEQLLREERE 1039
Query: 653 LIVKHKFTKAYKSVERFLQEDQAMGVYLYGELMVSEDARQQQLARRCFERTKEQMDRSSA 712
+ + Y+ E QE++ L GE E R+Q+L R+ R +E++ +
Sbjct: 1040 KRRLQERERQYREEEELQQEEE----QLLGE--ERETRRRQELERQ--YRKEEELQQEEE 1091
Query: 713 QVVAE 717
Q++ E
Sbjct: 1092 QLLRE 1096
Score = 31.2 bits (69), Expect = 3.5
Identities = 38/165 (23%), Positives = 68/165 (41%), Gaps = 21/165 (12%)
Query: 563 QRERRAGAECGLARQVRAEVTKWIGVNRRPRKRKRREKEEVFEKLLPDQLVLLLEHLLEQ 622
QRER+ AE RQ R + + R+R+RRE+E+ + L ++ L +Q
Sbjct: 793 QRERQLRAE---ERQQREQRFLPEEEEKEQRRRQRREREKELQ-FLEEEEQLQRRERAQQ 848
Query: 623 KTLSPRTLQSLQRTYHLQDQDAEVRHRW----------CELIVKHKFTKAYKSVERFLQE 672
LQ Q Q+Q + + RW L K + + ++ LQE
Sbjct: 849 LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE 908
Query: 673 DQAMGVYLYGELMVSEDARQQQLARRCFERTKEQMDRSSAQVVAE 717
++ EL E ++++ + R +EQ+ + Q++ E
Sbjct: 909 EEE-------ELQREEREKRRRQEQERQYREEEQLQQEEEQLLRE 946
Score = 30.8 bits (68), Expect = 4.6
Identities = 35/156 (22%), Positives = 65/156 (41%), Gaps = 27/156 (17%)
Query: 562 LQRERRAGAECGLARQVRAEVTKWIGVNRRPRKRKRREKEEVFEKLLPDQLVLLLEHLLE 621
L+RE++ E L R+ E + R +R +RE+EE L+
Sbjct: 413 LRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEE-------------RRDWLK 459
Query: 622 QKTLSPRTLQSLQRTYHLQDQDAEVRHRWCELIVKHKFTKAYKSVERFLQEDQAMGVYLY 681
++ + R Q ++ +DQ+ E R RW +L + + + + ++ +E
Sbjct: 460 REEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRRE--------- 510
Query: 682 GELMVSEDARQQQLARRCFERTKEQMDRSSAQVVAE 717
E+ R+Q+L R+ E +Q RS Q+ E
Sbjct: 511 -----QEERREQRLKRQEEEERLQQRLRSEQQLRRE 541
Score = 30.8 bits (68), Expect = 4.6
Identities = 33/150 (22%), Positives = 65/150 (43%), Gaps = 15/150 (10%)
Query: 563 QRERRAGAECGLARQVRAEVTKWIGVNRRPRKRKRREKEEVFEKLLPDQLVLLLEHLLEQ 622
QR+R E L R+ + E + ++ ++ R E+EE + D+ E LL++
Sbjct: 1288 QRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQE 1347
Query: 623 KTLSPRTLQSLQRTYHLQDQDAEVRHRWCELIVKHKFTKAYKSVERFLQEDQAMGVYLYG 682
+ P Q R + ++ E+RH+ + + + E+ L+ + +L
Sbjct: 1348 REEQPLRRQERDRKF----REEELRHQ--------EQGRKFLEEEQRLRRQERERKFLKE 1395
Query: 683 ELMVSEDARQQQLAR---RCFERTKEQMDR 709
E + R+QQL + R F ++Q+ R
Sbjct: 1396 EQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425
>gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
sapiens]
Length = 482
Score = 32.3 bits (72), Expect = 1.6
Identities = 20/85 (23%), Positives = 43/85 (50%), Gaps = 9/85 (10%)
Query: 533 ENIPEEKRLELSVENIYQDWL---ESSGIPKPLQRERRAGAECGLARQVRAEVTKWIGVN 589
+ + EEK LE + ++++WL + + +++E+ A+ Q R +W
Sbjct: 56 QQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQ 115
Query: 590 RRPR------KRKRREKEEVFEKLL 608
R+ R +++++EKEE +K+L
Sbjct: 116 RKEREEEEQKRQEKKEKEEALQKML 140
>gi|29570800 cadherin-like 26 isoform a [Homo sapiens]
Length = 832
Score = 32.3 bits (72), Expect = 1.6
Identities = 24/91 (26%), Positives = 42/91 (46%), Gaps = 6/91 (6%)
Query: 3 IQLDPARDDLPLMANTSHILVKHYVLDLDVDFESQVIEGTIVLFLEDGN---RFKKQNSS 59
I ++P + P + N+ ++++ H V D F Q GT++LFL D N + S
Sbjct: 449 ITVEPIDRESPHVNNSFYVIIIHAV---DDGFPPQTATGTLMLFLSDINDNVPTLRPRSR 505
Query: 60 IEEACQSESNKACKFGMPEPCHIPVTNARTF 90
E C+S ++ +P P ++ TF
Sbjct: 506 YMEVCESAVHEPLHIEAEDPDLEPFSDPFTF 536
>gi|194239713 laeverin [Homo sapiens]
Length = 990
Score = 31.6 bits (70), Expect = 2.7
Identities = 20/83 (24%), Positives = 37/83 (44%), Gaps = 2/83 (2%)
Query: 479 EKIFMQVHYLKGYFLLRFLAKRLGDETYFSFLRKFVHTFHGQLILSQDFLQMLLENIPEE 538
+++F Y KG + R L+ L + + S L+ ++ TF D + I ++
Sbjct: 495 QELFDIFTYSKGASMARMLSCFLNEHLFVSALKSYLKTFSYSNAEQDDLWRHFQMAIDDQ 554
Query: 539 KRLEL--SVENIYQDWLESSGIP 559
+ L +++NI W SG P
Sbjct: 555 STVILPATIKNIMDSWTHQSGFP 577
>gi|197209826 chromosome 2 open reading frame 21 isoform 1 [Homo
sapiens]
Length = 3258
Score = 31.2 bits (69), Expect = 3.5
Identities = 21/64 (32%), Positives = 29/64 (45%)
Query: 499 KRLGDETYFSFLRKFVHTFHGQLILSQDFLQMLLENIPEEKRLELSVENIYQDWLESSGI 558
+++G + FL V T +L + F+Q L P E ELS D LE I
Sbjct: 2826 RKVGGLALWDFLDFIVRTRIPIFVLLRPFIQCKLLAQPAENHEELSARQHIADQLERRFI 2885
Query: 559 PKPL 562
P+PL
Sbjct: 2886 PRPL 2889
>gi|70980531 GGA binding partner [Homo sapiens]
Length = 441
Score = 30.0 bits (66), Expect = 7.8
Identities = 23/119 (19%), Positives = 56/119 (47%), Gaps = 7/119 (5%)
Query: 595 RKRREKEEVFEKLLPDQLVLLLEHL-----LEQKTLSPRTLQSLQRTY-HLQDQDAEVRH 648
++ +E++E+ EK L ++ E L LE++ + L+ ++ +L+ AE R
Sbjct: 279 QQSQEQKEILEKCLEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERE 338
Query: 649 RWCELIVKHKFTKAYKSVERFLQEDQAMGVYLYGELMVSEDARQQQLARRCFERTKEQM 707
W K + K + +++ +QE + + ++ E R ++ +RT++++
Sbjct: 339 LWKTEHAKDQ-EKVSQEIQKAIQEQRKISQETVKAAIIEEQKRSEKAVEEAVKRTRDEL 396
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.133 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,696,365
Number of Sequences: 37866
Number of extensions: 1337762
Number of successful extensions: 3311
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 3280
Number of HSP's gapped (non-prelim): 58
length of query: 720
length of database: 18,247,518
effective HSP length: 110
effective length of query: 610
effective length of database: 14,082,258
effective search space: 8590177380
effective search space used: 8590177380
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.